@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1009: (2016-04-27 )
MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMRVTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQISLDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVSAKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEGMQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVTFAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDGSIWDAIAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQIAVAEVTRLRQGWGAWPVCAARAGAR
Atome Classification :
(20 SA)
.........10........20........30........-40........50........60........70..---------------......80........90........100.......110....------...120....--------...130.......140.......150.......160....----...170.......180.-......190.......200.......210.......220..------.....230.......240.......250.......260.......270.....----------------..280.......290.......300.......310..-----.....320.......330.......340..-----.....350.......360----------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
R
L
V
V
G
A
L
L
L
V
L
A
FAG
G
Y
A
V
A
A
C
K
T
V
T
L
T
VDG
T
A
M
R
V
T
-
T
M
K
S
R
V
I
D
I
V
EENGFSVDDRDDLYPAAG
V
Q
V
HDA---------------
D
T
I
V
L
RRSR
P
L
Q
I
S
LDGHD
A
K
Q
VW
T
T
A
S
T
V
D
E
A
L
A
Q
L
AMTDTA------PAAASRASRV--------PLSGMA
L
P
V
V
S
A
K
T
V
Q
LNDG
G
L
V
R
T
V
HLPAP
N
V
A
G
L
L
S
AA----GVPLLQSDHVVPAATAP-IVEG
M
Q
I
Q
V
T
R
N
R
I
K
K
V
T
E
RLPLPPNARRVEDPEMN
M
S
R
E
V
------
V
EDPGVPGTQ
D
V
T
F
A
V
A
E
VNGVETGR
L
P
V
A
N
V
V
VTPA
H
E
A
V
V
R
VGTKPGTEVP----------------PVID
G
S
I
W
D
A
I
A
GCEAGG
N
W
A
I
NTGNGYYG
G
V
Q
FDQ
G
-----
T
W
EANGG
L
R
YAPRADLA
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
QGWGAW
P
V
C
AARAGAR----------------------------------------------------------
50
Fugue
97.52
100%
-64
- C5 -
5E27
-
RPFB_MYCTU
A:
[137-362]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
K
T
V
Q
L
N
D
G
G
L
V
R
T
V
H
L
P
A
P
N
V
A
G
L
L
S
A
A
----
G
V
P
L
L
Q
S
D
H
V
V
P
A
A
T
A
P
-
I
V
E
G
M
Q
I
Q
V
T
R
N
R
I
K
K
V
T
E
R
L
P
L
P
P
N
A
R
R
V
E
D
P
E
M
N
M
S
R
E
V
------
V
E
D
P
G
V
P
G
T
Q
D
V
T
F
A
V
A
E
V
N
G
V
E
T
G
R
L
P
V
A
N
V
V
V
T
P
A
H
E
A
V
V
R
V
G
T
K
P
G
T
E
V
P
----------------
P
V
I
D
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
29
HHSearch
97.21
100%
-64
- C5 -
5E27
-
RPFB_MYCTU
A:
[137-362]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
K
T
V
Q
L
N
D
G
G
L
V
R
T
V
H
L
P
A
P
N
V
A
G
L
L
S
A
A
----
G
V
P
L
L
Q
S
D
H
V
V
P
A
A
T
A
P
-
I
V
E
G
M
Q
I
Q
V
T
R
N
R
I
K
K
V
T
E
R
L
P
L
P
P
N
A
R
R
V
E
D
P
E
M
N
M
S
R
E
V
------
V
E
D
P
G
V
P
G
T
Q
D
V
T
F
A
V
A
E
V
N
G
V
E
T
G
R
L
P
V
A
N
V
V
V
T
P
A
H
E
A
V
V
R
V
G
T
K
P
G
T
E
V
P
----------------
P
V
I
D
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
1
PsiBlast_PDB
97.21
100%
-64
- C5 -
5E27
-
RPFB_MYCTU
A:
[137-362]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
K
T
V
Q
L
N
D
G
G
L
V
R
T
V
H
L
P
A
P
N
V
A
G
L
L
S
A
A
----
G
V
P
L
L
Q
S
D
H
V
V
P
A
A
T
A
P
-
I
V
E
G
M
Q
I
Q
V
T
R
N
R
I
K
K
V
T
E
R
L
P
L
P
P
N
A
R
R
V
E
D
P
E
M
N
M
S
R
E
V
------
V
E
D
P
G
V
P
G
T
Q
D
V
T
F
A
V
A
E
V
N
G
V
E
T
G
R
L
P
V
A
N
V
V
V
T
P
A
H
E
A
V
V
R
V
G
T
K
P
G
T
E
V
P
----------------
P
V
I
D
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
52
Fugue
79.93
97%
-35
- C5 -
3EO5
-
RPFB_MYCTU
A:
[192-362]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
N
R
I
K
K
V
T
E
R
L
P
L
P
P
N
A
R
R
V
E
D
P
E
M
N
M
S
R
E
V
------
V
E
D
P
G
V
P
G
T
Q
D
V
T
F
A
V
A
E
V
N
G
V
E
T
G
R
L
P
V
A
N
V
V
V
T
P
A
H
E
A
V
V
R
V
G
T
K
P
G
T
E
V
P
----------------
P
--
V
I
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
51
Fugue
65.27
100%
-55
- C5 -
1XSF
-
A:
[1-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
V
V
T
P
A
H
E
A
V
V
R
V
G
T
K
P
G
T
E
V
P
----------------
P
V
I
D
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
2
PsiBlast_PDB
65.27
100%
-55
- C5 -
1XSF
-
A:
[1-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
V
V
T
P
A
H
E
A
V
V
R
V
G
T
K
P
G
T
E
V
P
----------------
P
V
I
D
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
24
PsiBlast_CBE
61.39
100%
-44
- C5 -
4KPM
2
RPFB_MYCTU
B:
[1-80]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
25
PsiBlast_CBE
61.14
100%
-40
- C5 -
4KL7
1
RPFB_MYCTU
B:
[1-80]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
22
PsiBlast_CBE
60.80
100%
-36
- C5 -
4EMN
4
RPFB_MYCTU
B:
[2-81]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
5
PsiBlast_PDB
60.37
100%
-43
- C5 -
4KPM
3
RPFB_MYCTU
A:
[1-80]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
3
PsiBlast_PDB
59.99
100%
-37
- C5 -
4EMN
4
RPFB_MYCTU
A:
[1-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
31
HHSearch
58.77
100%
-37
- C5 -
4EMN
4
RPFB_MYCTU
A:
[2-81]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
4
PsiBlast_PDB
58.53
100%
-41
- C5 -
4KL7
1
RPFB_MYCTU
A:
[1-80]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
23
PsiBlast_CBE
58.37
100%
-36
- C5 -
4KPM
1
RPFB_MYCTU
C:
[1-80]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
21
PsiBlast_CBE
58.24
100%
-37
- C5 -
4EMN
2
RPFB_MYCTU
C:
[1-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
-----
T
W
E
A
N
G
G
L
R
Y
A
P
R
A
D
L
A
T
R
E
E
Q
I
A
V
A
E
V
T
R
-----
L
R
Q
G
W
G
A
W
P
V
C
A
A
R
A
G
A
R
----------------------------------------------------------
56
Fugue
57.68
18%
-39
- C3 -
1ZR6
7
?
A:
[3-481]
---
E
A
E
F
N
S
I
N
A
C
L
A
A
A
D
V
E
F
H
E
E
D
S
E
G
W
D
M
D
G
T
A
F
N
L
R
V
D
Y
D
P
A
A
I
A
I
P
R
-
S
T
E
D
I
A
A
A
V
Q
C
G
L
D
A
G
V
Q
I
S
A
K
G
GGHSYGSYGFGGED
G
H
L
M
L
E
L
D
R
M
Y
R
V
S
V
D
D
N
N
V
A
T
I
Q
G
G
A
R
L
G
Y
T
A
L
E
L
L
D
Q
G
N
R
A
L
S
H
G
TC
P
A
V
G
V
G
G
H
V
L
G
G
G
Y
G
FAT
H
T
H
G
L
T
L
D
W
L
I
G
A
T
V
V
L
A
D
A
S
---
I
V
H
V
S
E
T
E
N
A
D
L
F
W
A
L
R
G
GG
G
G
F
A
I
V
S
E
F
E
F
N
T
F
E
A
P
E
I
I
T
T
Y
Q
V
T
T
T
W
N
R
K
Q
H
V
A
G
L
K
A
L
Q
D
W
A
Q
N
T
M
P
R
E
L
S
M
R
L
E
I
N
AN
A
L
N
W
E
G
N
F
F
G
N
A
K
D
L
K
K
I
L
Q
P
I
M
K
K
A
G
G
K
S
T
I
S
K
L
V
E
T
D
W
Y
G
Q
I
N
T
Y
L
Y
G
A
D
L
N
I
T
YN
Y
D
V
H
E
Y
F
Y
A
N
S
L
T
A
P
R
L
S
D
E
A
I
Q
A
F
V
D
Y
K
F
D
-
N
S
S
V
R
P
G
R
G
W
W
I
Q
W
D
F
H
G
G
KNSAL
A
A
V
S
N
D
E
T
A
Y
A
H
R
D
Q
L
W
L
W
Q
F
Y
D
S
I
Y
D
Y
E
N
NTSPY
P
E
S
G
F
E
F
M
Q
G
F
V
A
T
I
E
D
T
LPEDR
K
G
K
Y
FNYADTTLT
K
E
E
A
Q
K
L
Y
WRGN
L
E
K
L
Q
A
I
K
A
K
Y
DPEDVFGNVVSVEPIAY
27
PsiBlast_CBE
52.38
57%
-23
- C5 -
4OW1
1
RPFC_MYCTU
T:
[6-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
A
V
A
Q
C
E
S
G
G
N
W
A
A
N
T
G
N
G
K
Y
G
G
L
Q
F
K
P
A
-----
T
W
A
A
F
G
G
V
G
N
-
P
A
A
--
A
S
R
E
Q
Q
I
A
V
A
N
R
V
L
-----
A
E
Q
G
L
D
A
W
P
T
C
G
A
A
S
G
------------------------------------------------------------
7
PsiBlast_PDB
51.77
57%
-19
- C5 -
4OW1
1
RPFC_MYCTU
A:
[6-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
A
V
A
Q
C
E
S
G
G
N
W
A
A
N
T
G
N
G
K
Y
G
G
L
Q
F
K
P
A
-----
T
W
A
A
F
G
G
V
G
N
-
P
A
A
--
A
S
R
E
Q
Q
I
A
V
A
N
R
V
L
-----
A
E
Q
G
L
D
A
W
P
T
C
G
A
A
S
G
------------------------------------------------------------
26
PsiBlast_CBE
51.35
57%
-19
- C5 -
4OW1
1
RPFC_MYCTU
W:
[6-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
A
V
A
Q
C
E
S
G
G
N
W
A
A
N
T
G
N
G
K
Y
G
G
L
Q
F
K
P
A
-----
T
W
A
A
F
G
G
V
G
N
-
P
A
A
--
A
S
R
E
Q
Q
I
A
V
A
N
R
V
L
-----
A
E
Q
G
L
D
A
W
P
T
C
G
A
A
S
G
------------------------------------------------------------
32
HHSearch
49.95
55%
-19
- C5 -
4OW1
1
RPFC_MYCTU
A:
[4-79]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
W
D
A
V
A
Q
C
E
S
G
G
N
W
A
A
N
T
G
N
G
K
Y
G
G
L
Q
F
K
P
A
-----
T
W
A
A
F
G
G
V
G
N
---
P
A
A
A
S
R
E
Q
Q
I
A
V
A
N
R
V
L
-----
A
E
Q
G
L
D
A
W
P
T
C
G
A
A
S
G
L
-----------------------------------------------------------