@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Rv1077: (2016-04-28 )
MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR

Atome Classification :

(59 SA) ------------------------------------.........10........20.---...---.-------.--..---30........40........50........60..--.-.--..-.-.70........80........90........100.......110.......------------120--.......----..130.......140.......150.......160.......170.......180.......190.......-200.-.....-.210-.------....---.------.------.------220.......230.......240.......250.......260.......270.......280--.-.---.-...-..290.......300..-.....310.......320-.......330.......340-.-......350.......360.......370.......380.......390.......400.......410.......420.......430........440---..-----..----.--...------.450.......460..
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) ------------------------------------MRIAQHISELIGGTPLVRLNSV---VPD---G-------A--GT---VAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKP--G-G--TI-V-EPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTA------------V----PPHDPAS----YYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLKEVSGG-RVRI-VGADP-EGS--V------YSGG---A------G------R------PYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVA---E-E---A-GPD-ALIVVLLPDGGRGYMSK-IFNDAWMSSYGFLRSRLD-GSTEQSTVGDVLRRKSGALP-A-LVHTHPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALR-DWDALMVVE-----EG-----KP----V--GVI------TRYDLLGFLSEGAGRR
101 HHSearch 91.9439% -73 - C2 -4COO CBS_HUMAN A:[98-560] --------------------------------------ILPDILKKIGDTPMVRINKI---GKK---F-------GLKCE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCP--GCRI-IGVDP-EGS--I------LAEPEELNQTE---Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKEEDLTEKK--PWWWHLR-VQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDEA-----GVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILE-MDHFALVVHE----Q------MV----F--GVV------TAIDLLNFVAAQER--
102 HHSearch 90.4536% -69 - C2 -3PC3 ? A:[51-513] ---------------------------------------TPNILEVIGCTPLVKLNNI---PAS---DGI-----E--CE---MYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP--G-Y--TI-I-EPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTE------------A----AYDSPEG----LIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVP--SCQI-VGVDP-YGS--I------LARP---AELNKTDV------Q------FYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA---R-K---L-KKG-QRCVVILPDGIRNYMTK-FVSDNWMEARNFKEPVNE-HG---HWWWSLA-IAELELPAP-PVILKSDATVGEAIALMKKHRVDQLPVVDQDD----GSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLE-VDPSVLILGKNPAGKV-----EL----K--ALA------TKLDVTTFIAAGK---
122 Fugue 89.4635% -64 - C2 -3PC3 ? A:[12-515] YERPADFIDPGKPSKCKWHLGTAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNI---PAS---DGI-----E--CE---MYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP--G-Y--TI-I-EPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTE------------A----AYDSPEG----LIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPS--CQI-VGVDP-YGS--I------LARP---A------E------LNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA---R-K---L-KKG-QRCVVILPDGIRNYMTK-FVSDNWMEARNFKEPVNE-HGHWWW---SLAIAELELPA-P-PVILKSDATVGEAIALMKKHRVDQLPVVDQDD----GSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLE-VDPSVLILG-----KNPAGKVEL----K--ALA------TKLDVTTFIAAGKQK-
2 PsiBlast_PDB 89.3939% -70 - C2 -4COO CBS_HUMAN A:[97-556] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-DLTEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE-----Q------------MVFGVV------TAIDLLNFVA------
3 PsiBlast_PDB 89.2739% -72 - C2 -4L0D CBS_HUMAN A:[75-534] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-D-TEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE-----Q------------MVFGVV------TAIDLLNFVA------
24 PsiBlast_CBE 88.9239% -71 - C2 -4L0D CBS_HUMAN B:[75-534] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-DLTEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE-----Q------------MVFGVV------TAIDLLNFVA------
26 PsiBlast_CBE 88.8139% -71 - C2 -4L3V CBS_HUMAN A:[74-543] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-DLTEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE--------------RQMVF--GVV------TAIDLLNFVA------
23 PsiBlast_CBE 88.6939% -71 - C2 -4COO CBS_HUMAN B:[97-556] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLK----------KPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE-----Q-------Q----MVFGVV------TAIDLLNFVA------
4 PsiBlast_PDB 88.6839% -71 - C2 -4L28 CBS_HUMAN A:[74-543] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-D-TEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFNQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE--------------QMV-F--GVV------TAIDLLNFVA------
5 PsiBlast_PDB 88.5839% -72 - C2 -4L3V CBS_HUMAN B:[74-543] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-DLTEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE--------------RQMVF--GVV------TAIDLLNFVA------
21 PsiBlast_CBE 88.2239% -72 - C2 -4PCU CBS_HUMAN B:[75-534] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPSS----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-D------WWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE-----QQ-----RQ----MVFGVV------TAIDLLNFVA------
25 PsiBlast_CBE 88.1639% -70 - C2 -4L3V CBS_HUMAN C:[74-543] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-DLTEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFDQAPVVDE-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE--------------RQMVF--GVV------TAIDLLNFVA------
22 PsiBlast_CBE 87.3639% -70 - C2 -4L27 CBS_HUMAN D:[74-533] -------------------------------------KILPDILKKIGDTPMVRINKI---GKK---FGL-----K--CE---LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP--G-D--TI-I-EPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN------------A----RFDSPES----HVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPG--CRI-IGVDP-EGS--ILAEPEELNQT---E------Q------T------TYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAA---Q-E---L-QEG-QRCVVILPDSVRNYMTK-FLSDRWMLQKGFLKE--E-D-TEKKPWWWHLRVQELGLS-A-PLTVLPTITCGHTIEILREKGFNQAPVV-E-----AGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHE-----Q------------MVFGVV------TAIDLLNFVA------
10 PsiBlast_PDB 86.0735% -62 - C2 -3PC3 ? A:[49-515] -------------------------------------QITPNILEVIGCTPLVKLNNIP--ASD---G-------I--ECE--MYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP--G-Y--TI-I-EPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTE------------A----AYDSPEG----LIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKE-QVP-SCQI-VGVDP-YGS--I------LARP---A------ELNKTDVQ------FYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA---R-K---L-KKG-QRCVVILPDGIRNYMTK-FVSDNWMEARNF----KE-PVNEHGHWWWSLAIAELELP-APPVILKSDATVGEAIALMKKHRVDQLPVVDQD----DGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVL--EVDPSVLIL-----GK-----NP----A--GKVELKALATKLDVTTFIAAGKQK-
9 PsiBlast_PDB 85.4935% -66 - C2 -3PC2 ? A:[49-513] -------------------------------------QITPNILEVIGCTPLVKLNNIP--ASD---G-------I--ECE--MYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP--G-Y--TI-I-EPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTE------------A----AYDSPEG----LIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKE-QVP-SCQI-VGVDP-YGS--I------LARP---A------ELNKTDVQ------FYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA---R-K---L-KKG-QRCVVILPDGIRNYMTK-FVSDNWMEARNF----KE-PVNEHGHWWWSLAIAELELP-APPVILKSDATVGEAIALMKKHRVDQLPVVDQD----DGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVL--EVDPSVLIL-----GK-----NP----A--GKVELKALATKLDVTTFIAAGK---
11 PsiBlast_PDB 85.4635% -63 - C2 -3PC4 ? A:[49-515] -------------------------------------QITPNILEVIGCTPLVKLNNIP--ASD---G-------I--ECE--MYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP--G-Y--TI-I-EPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTE------------A----AYDSPEG----LIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKE-QVP-SCQI-VGVDP-YGS--I------LARP---A------ELNKTDVQ------FYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA---R-K---L-KKG-QRCVVILPDGIRNYMTK-FVSDNWMEARNF----KE-PVNEHGHWWWSLAIAELELP-APPVILKSDATVGEAIALMKKHRVDQLPVVDQD----DGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVL--EVDPSVLIL-----GK-----NP----A--GKVELKALATKLDVTTFIAAGKQK-