@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1092c: (2016-04-28 )
MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
Atome Classification :
(45 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......-------210-----.-------........220.......230.......240.......250.......260.......270.......280.......290.......300.......310
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSRLSEPSPY
V
E
F
D
R
R
Q
W
R
A
LRMSTPLAL
T
E
E
E
L
V
G
L
RGLGEQI
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
LGEPQQNPDRPV
P
F
I
I
GVAGSVAVGK
S
T
T
A
R
V
L
Q
A
L
L
A
RWDHHPR
V
D
L
V
TTD
G
F
LYPN
A
E
L
Q
R
R
N
L
M
HRKGF
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
VKSGSDY
A
C
A
P
V
Y
S
HLHYDIIP
G
A
E
Q
V
VRHP
D
I
L
I
L
EGLNVLQTG-------P-------
T
-------
L
M
V
S
DLFD
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
RTTAFADPESH
F
H
H
Y
AAFSDS
Q
A
V
V
A
A
R
E
I
W
R
TINR
P
N
L
V
E
N
ILPTRP
R
A
T
L
V
L
RKDADHS
I
N
R
L
RLRKL
16
PsiBlast_PDB
99.18
100%
-129
- C3 -
3AVO
10
COAA_MYCTU
A:
[16-322]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
32
PsiBlast_CBE
98.62
100%
-129
- C3 -
4BFT
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
15
PsiBlast_PDB
98.58
100%
-129
- C3 -
3AVP
15
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
17
PsiBlast_PDB
98.55
100%
-126
- C3 -
3AVQ
11
COAA_MYCTU
A:
[16-322]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
9
PsiBlast_PDB
98.53
100%
-125
- C3 -
3AEZ
16
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
3
PsiBlast_PDB
98.39
100%
-128
- C3 -
2ZS9
13
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
1
PsiBlast_PDB
98.39
100%
-128
- C3 -
2ZS7
14
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
14
PsiBlast_PDB
98.38
100%
-127
- C3 -
3AF4
14
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
6
PsiBlast_PDB
98.34
100%
-130
- C3 -
2ZSD
13
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
27
PsiBlast_CBE
98.08
100%
-126
- C3 -
4BFW
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
31
PsiBlast_CBE
98.04
100%
-129
- C3 -
4BFU
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
36
PsiBlast_CBE
98.01
99%
-128
- C3 -
2GES
1
COAA_MYCTU
A:
[5-312]
----
S
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
5
PsiBlast_PDB
98.00
100%
-128
- C3 -
2ZSB
7
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
10
PsiBlast_PDB
97.97
100%
-126
- C3 -
3AF0
11
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
28
PsiBlast_CBE
97.77
100%
-128
- C3 -
4BFW
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
35
PsiBlast_CBE
97.71
99%
-130
- C3 -
2GET
3
COAA_MYCTU
A:
[5-312]
----
S
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
13
PsiBlast_PDB
97.70
100%
-128
- C3 -
3AF3
11
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
34
PsiBlast_CBE
97.65
99%
-129
- C3 -
2GEU
1
COAA_MYCTU
A:
[5-312]
----
S
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
---
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
4
PsiBlast_PDB
97.58
100%
-127
- C3 -
2ZSA
18
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
26
PsiBlast_CBE
97.57
100%
-128
- C3 -
4BFX
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
12
PsiBlast_PDB
97.56
100%
-126
- C3 -
3AF2
12
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
25
PsiBlast_CBE
97.54
100%
-130
- C3 -
4BFX
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
20
PsiBlast_PDB
97.40
100%
-130
- C3 -
4BFU
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
11
PsiBlast_PDB
97.38
100%
-126
- C3 -
3AF1
17
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
8
PsiBlast_PDB
97.37
100%
-128
- C3 -
2ZSF
12
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
29
PsiBlast_CBE
97.27
100%
-127
- C3 -
4BFV
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
69
HHSearch
97.18
100%
-131
- C3 -
4BFZ
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
22
PsiBlast_CBE
97.18
100%
-131
- C3 -
4BFZ
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
33
PsiBlast_CBE
97.12
99%
-127
- C3 -
2GEV
8
COAA_MYCTU
A:
[5-312]
----
S
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
30
PsiBlast_CBE
97.00
100%
-129
- C3 -
4BFV
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
21
PsiBlast_CBE
96.88
100%
-129
- C3 -
4BFZ
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
18
PsiBlast_PDB
96.78
100%
-129
- C3 -
4BFS
1
COAA_MYCTU
A:
[12-318]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
-----
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
23
PsiBlast_CBE
96.76
100%
-131
- C3 -
4BFY
2
COAA_MYCTU
B:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
19
PsiBlast_PDB
96.72
100%
-129
- C3 -
4BFT
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
24
PsiBlast_CBE
96.66
100%
-129
- C3 -
4BFY
2
COAA_MYCTU
A:
[13-318]
------
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
2
PsiBlast_PDB
96.53
100%
-128
- C3 -
2ZS8
6
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
7
PsiBlast_PDB
96.47
100%
-124
- C3 -
2ZSE
16
COAA_MYCTU
A:
[6-312]
-----
E
P
S
P
Y
V
E
F
D
R
R
Q
W
R
A
L
R
M
S
T
P
L
A
L
T
E
E
E
L
V
G
L
R
G
L
G
E
Q
I
D
L
L
E
V
E
E
V
Y
L
P
L
A
R
L
I
H
L
Q
V
A
A
R
Q
R
L
F
A
A
T
A
E
F
L
G
E
P
Q
Q
N
P
D
R
P
V
P
F
I
I
G
V
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
A
R
W
D
H
H
P
R
V
D
L
V
T
T
D
G
F
L
Y
P
N
A
E
L
Q
R
R
N
L
M
H
R
K
G
F
P
E
S
Y
N
R
R
A
L
M
R
F
V
T
S
V
K
S
G
S
D
Y
A
C
A
P
V
Y
S
H
L
H
Y
D
I
I
P
G
A
E
Q
V
V
R
H
P
D
I
L
I
L
E
G
L
N
V
L
Q
T
G
-------
P
-------
T
-------
L
M
V
S
D
L
F
D
F
S
L
Y
V
D
A
R
I
E
D
I
E
Q
W
Y
V
S
R
F
L
A
M
R
T
T
A
F
A
D
P
E
S
H
F
H
H
Y
A
A
F
S
D
S
Q
A
V
V
A
A
R
E
I
W
R
T
I
N
R
P
N
L
V
E
N
I
L
P
T
R
P
R
A
T
L
V
L
R
K
D
A
D
H
S
I
N
R
L
R
L
R
K
L
70
HHSearch
84.23
54%
-121
* C3 *
4NE2
3
COAA_KLEP3
A:
[26-334]
-----
L
M
T
P
Y
L
Q
F
N
R
H
Q
W
A
A
L
R
-----
T
L
T
E
D
E
I
T
R
L
K
G
I
N
E
D
L
S
L
E
E
V
A
E
I
Y
L
P
L
S
R
L
L
N
F
Y
I
S
S
N
L
R
R
Q
A
V
L
E
Q
F
L
G
T
N
----
G
Q
R
I
P
Y
I
I
S
I
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
S
R
W
P
E
H
R
H
V
E
L
I
T
T
D
G
F
L
H
P
N
S
V
L
K
E
R
G
L
M
K
K
K
G
F
P
Q
S
Y
D
M
H
R
L
V
K
F
V
S
D
L
K
S
G
V
P
Q
A
T
A
P
V
Y
S
H
L
I
Y
D
V
I
P
D
G
D
K
T
V
A
Q
P
D
I
L
I
L
E
G
L
N
V
L
Q
S
G
MDYPHDP
H
-------
H
-------
V
F
V
S
D
F
V
D
F
S
I
Y
V
D
A
P
E
E
L
L
K
S
W
Y
I
N
R
F
L
K
F
R
E
G
A
F
T
D
P
D
S
Y
F
H
N
Y
A
K
L
S
K
E
E
A
V
D
I
A
T
S
L
W
N
E
I
N
L
M
N
L
K
E
N
I
L
P
T
R
E
R
A
S
L
I
M
T
K
S
A
N
H
S
V
N
Q
V
R
L
R
K
-
55
PsiBlast_CBE
84.05
51%
-121
- C3 -
3TQC
1
COAA_COXBU
B:
[13-321]
------
I
T
P
Y
L
Q
F
N
R
Q
Q
W
G
N
F
----
P
L
T
L
T
E
S
D
L
D
K
L
Q
G
Q
I
E
I
V
S
L
K
E
V
T
E
I
Y
L
P
L
S
R
L
L
S
F
Y
V
T
A
R
Q
T
L
Q
Q
A
T
Y
Q
F
L
G
K
P
E
P
K
----
V
P
Y
I
I
G
I
A
G
S
V
A
V
G
K
S
T
T
S
R
V
L
K
A
L
L
S
R
W
P
D
H
P
N
V
E
V
I
T
T
D
G
F
L
Y
S
N
A
K
L
E
K
Q
G
L
M
K
R
K
G
F
P
E
S
Y
D
M
P
S
L
L
R
V
L
N
A
I
K
S
G
Q
R
N
V
R
I
P
V
Y
S
H
H
Y
Y
D
I
V
R
G
Q
Y
E
I
V
D
Q
P
D
I
V
I
L
E
G
L
N
I
L
Q
T
G
-------
V
RKTLQ
Q
L
Q
-------
V
F
V
S
D
F
F
D
F
S
L
F
V
D
A
Q
A
Q
V
I
Q
K
W
Y
I
D
R
V
L
S
F
W
R
T
T
F
K
D
P
H
S
Y
F
H
Y
L
T
Q
M
S
E
T
E
V
A
A
F
A
K
H
V
W
N
E
I
N
K
V
N
L
M
E
N
I
L
P
Y
K
N
R
A
Q
L
I
L
E
K
A
A
D
H
S
I
Q
K
V
Y
L
R
K
I
71
HHSearch
84.01
53%
-120
- C3 -
3TQC
1
COAA_COXBU
A:
[13-320]
------
I
T
P
Y
L
Q
F
N
R
Q
Q
W
G
N
------
L
T
L
T
E
S
D
L
D
K
L
Q
G
Q
I
E
I
V
S
L
K
E
V
T
E
I
Y
L
P
L
S
R
L
L
S
F
Y
V
T
A
R
Q
T
L
Q
Q
A
T
Y
Q
F
L
G
K
P
----
E
P
K
V
P
Y
I
I
G
I
A
G
S
V
A
V
G
K
S
T
T
S
R
V
L
K
A
L
L
S
R
W
P
D
H
P
N
V
E
V
I
T
T
D
G
F
L
Y
S
N
A
K
L
E
K
Q
G
L
M
K
R
K
G
F
P
E
S
Y
D
M
P
S
L
L
R
V
L
N
A
I
K
S
G
Q
R
N
V
R
I
P
V
Y
S
H
H
Y
Y
D
I
V
R
G
Q
Y
E
I
V
D
Q
P
D
I
V
I
L
E
G
L
N
I
L
Q
T
G
-------
V
RKTLQQ
L
Q
-------
V
F
V
S
D
F
F
D
F
S
L
F
V
D
A
Q
A
Q
V
I
Q
K
W
Y
I
D
R
V
L
S
F
W
R
T
T
F
K
D
P
H
S
Y
F
H
Y
L
T
Q
M
S
E
T
E
V
A
A
F
A
K
H
V
W
N
E
I
N
K
V
N
L
M
E
N
I
L
P
Y
K
N
R
A
Q
L
I
L
E
K
A
A
D
H
S
I
Q
K
V
Y
L
R
K
-
56
PsiBlast_CBE
83.80
51%
-121
- C3 -
3TQC
1
COAA_COXBU
A:
[13-321]
------
I
T
P
Y
L
Q
F
N
R
Q
Q
W
G
N
------
L
T
L
T
E
S
D
L
D
K
L
Q
G
Q
I
E
I
V
S
L
K
E
V
T
E
I
Y
L
P
L
S
R
L
L
S
F
Y
V
T
A
R
Q
T
L
Q
Q
A
T
Y
Q
F
L
G
K
P
E
P
K
----
V
P
Y
I
I
G
I
A
G
S
V
A
V
G
K
S
T
T
S
R
V
L
K
A
L
L
S
R
W
P
D
H
P
N
V
E
V
I
T
T
D
G
F
L
Y
S
N
A
K
L
E
K
Q
G
L
M
K
R
K
G
F
P
E
S
Y
D
M
P
S
L
L
R
V
L
N
A
I
K
S
G
Q
R
N
V
R
I
P
V
Y
S
H
H
Y
Y
D
I
V
R
G
Q
Y
E
I
V
D
Q
P
D
I
V
I
L
E
G
L
N
I
L
Q
T
G
-------
V
RKTLQQ
L
Q
-------
V
F
V
S
D
F
F
D
F
S
L
F
V
D
A
Q
A
Q
V
I
Q
K
W
Y
I
D
R
V
L
S
F
W
R
T
T
F
K
D
P
H
S
Y
F
H
Y
L
T
Q
M
S
E
T
E
V
A
A
F
A
K
H
V
W
N
E
I
N
K
V
N
L
M
E
N
I
L
P
Y
K
N
R
A
Q
L
I
L
E
K
A
A
D
H
S
I
Q
K
V
Y
L
R
K
I
38
PsiBlast_CBE
83.24
53%
-122
- C3 -
4NE2
3
COAA_KLEP3
A:
[28-334]
-------
T
P
Y
L
Q
F
N
R
H
Q
W
A
A
L
R
-----
T
L
T
E
D
E
I
T
R
L
K
G
I
N
E
D
L
S
L
E
E
V
A
E
I
Y
L
P
L
S
R
L
L
N
F
Y
I
S
S
N
L
R
R
Q
A
V
L
E
Q
F
L
G
T
N
G
Q
R
----
I
P
Y
I
I
S
I
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
S
R
W
P
E
H
R
H
V
E
L
I
T
T
D
G
F
L
H
P
N
S
V
L
K
E
R
G
L
M
K
K
K
G
F
P
Q
S
Y
D
M
H
R
L
V
K
F
V
S
D
L
K
S
G
V
P
Q
A
T
A
P
V
Y
S
H
L
I
Y
D
V
I
P
D
G
D
K
T
V
A
Q
P
D
I
L
I
L
E
G
L
N
V
L
Q
S
G
-------
M
-------
D
YPHDPHH
V
F
V
S
D
F
V
D
F
S
I
Y
V
D
A
P
E
E
L
L
K
S
W
Y
I
N
R
F
L
K
F
R
E
G
A
F
T
D
P
D
S
Y
F
H
N
Y
A
K
L
S
K
E
E
A
V
D
I
A
T
S
L
W
N
E
I
N
L
M
N
L
K
E
N
I
L
P
T
R
E
R
A
S
L
I
M
T
K
S
A
N
H
S
V
N
Q
V
R
L
R
K
-
58
PsiBlast_CBE
82.44
52%
-120
- C3 -
1SQ5
2
COAA_ECOLI
B:
[2-308]
-------
T
P
Y
L
Q
F
D
R
N
Q
W
A
A
L
R
------
L
S
E
D
E
I
A
R
L
K
G
I
N
E
D
L
S
L
E
E
V
A
E
I
Y
L
P
L
S
R
L
L
N
F
Y
I
S
S
N
L
R
R
Q
A
V
L
E
Q
F
L
G
T
N
G
Q
R
----
I
P
Y
I
I
S
I
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
S
R
W
P
E
H
R
R
V
E
L
I
T
T
D
G
F
L
H
P
N
Q
V
L
K
E
R
G
L
M
K
K
K
G
F
P
E
S
Y
D
M
H
R
L
V
K
F
V
S
D
L
K
S
G
V
P
N
V
T
A
P
V
Y
S
H
L
I
Y
D
V
I
P
D
G
D
K
T
V
V
Q
P
D
I
L
I
L
E
G
L
N
V
L
Q
S
G
-------
M
-------
D
YPHDPHH
V
F
V
S
D
F
V
D
F
S
I
Y
V
D
A
P
E
D
L
L
Q
T
W
Y
I
N
R
F
L
K
F
R
E
G
A
F
T
D
P
D
S
Y
F
H
N
Y
A
K
L
T
K
E
E
A
I
K
T
A
M
T
L
W
K
E
I
N
W
L
N
L
K
Q
N
I
L
P
T
R
E
R
A
S
L
I
L
T
K
S
A
N
H
A
V
E
E
V
R
L
R
K
-
37
PsiBlast_CBE
82.42
53%
-118
- C3 -
4NE2
3
COAA_KLEP3
B:
[28-334]
-------
T
P
Y
L
Q
F
N
R
H
Q
W
A
A
L
R
-------
T
E
D
E
I
T
R
L
K
G
I
N
E
D
L
S
L
E
E
V
A
E
I
Y
L
P
L
S
R
L
L
N
F
Y
I
S
S
N
L
R
R
Q
A
V
L
E
Q
F
L
G
T
N
G
Q
R
----
I
P
Y
I
I
S
I
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
S
R
W
P
E
H
R
H
V
E
L
I
T
T
D
G
F
L
H
P
N
S
V
L
K
E
R
G
L
M
K
K
K
G
F
P
Q
S
Y
D
M
H
R
L
V
K
F
V
S
D
L
K
S
G
V
P
Q
A
T
A
P
V
Y
S
H
L
I
Y
D
V
I
P
D
G
D
K
T
V
A
Q
P
D
I
L
I
L
E
G
L
N
V
L
Q
S
G
-------
M
-------
D
YPHDPHH
V
F
V
S
D
F
V
D
F
S
I
Y
V
D
A
P
E
E
L
L
K
S
W
Y
I
N
R
F
L
K
F
R
E
G
A
F
T
D
P
D
S
Y
F
H
N
Y
A
K
L
S
K
E
E
A
V
D
I
A
T
S
L
W
N
E
I
N
L
M
N
L
K
E
N
I
L
P
T
R
E
R
A
S
L
I
M
T
K
S
A
N
H
S
V
N
Q
V
R
L
R
K
-
57
PsiBlast_CBE
81.26
52%
-121
- C3 -
1SQ5
2
COAA_ECOLI
D:
[2-308]
-------
T
P
Y
L
Q
F
D
R
N
Q
W
A
A
L
R
D
---
M
T
L
S
E
D
E
I
A
R
L
K
G
I
N
E
D
L
S
L
E
E
V
A
E
I
Y
L
P
L
S
R
L
L
N
F
Y
I
S
S
N
L
R
R
Q
A
V
L
E
Q
F
L
G
T
N
G
Q
R
----
I
P
Y
I
I
S
I
A
G
S
V
A
V
G
K
S
T
T
A
R
V
L
Q
A
L
L
S
R
W
P
E
H
R
R
V
E
L
I
T
T
D
G
F
L
H
P
N
Q
V
L
K
E
R
G
L
M
K
K
K
G
F
P
E
S
Y
D
M
H
R
L
V
K
F
V
S
D
L
K
S
G
V
P
N
V
T
A
P
V
Y
S
H
L
I
Y
D
V
I
P
D
G
D
K
T
V
V
-
P
D
I
L
I
L
E
G
L
N
V
L
Q
S
G
-------
M
-------
D
YPHDPHH
V
F
V
S
D
F
V
D
F
S
I
Y
V
D
A
P
E
D
L
L
Q
T
W
Y
I
N
R
F
L
K
F
R
E
G
A
F
T
D
P
D
S
Y
F
H
N
Y
A
K
L
T
K
E
E
A
I
K
T
A
M
T
L
W
K
E
I
N
W
L
N
L
K
Q
N
I
L
P
T
R
E
R
A
S
L
I
L
T
K
S
A
N
H
A
V
E
E
V
R
L
R
K
-