@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1098c: (2016-04-28 )
MAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAMAKAEQLDSDRL
Atome Classification :
(30 SA)
.........10........20........30........40...--.....50........60........70........80........90........100.......110.......120------.-.--.-----....130.......140.......150.....-..160.......170.......180.......190.......200.......210.......220.......230.......240.......250.....-..260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAVDADSA
N
Y
R
I
EHDTMGEVR
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
NFPISGR--GL
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
VNSDLGLLAPEKA
D
A
I
I
A
A
A
A
E
IADGQHDDQFP
I
D
V
F
QTGSGTSSNM
N
T
N
E
V
I
A
S
I
A
AK------G-
G
--
V
-----
T
LHPNDDVNMSQSSNDTFPTA
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
KA
L
D
W
H
T
V
V
KSGR
T
H
L
M
D
AVPVTLG
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
LAIGGTAVGTGLNAPD
D
F
G
V
R
V
V
A
V
L
V
A
QT
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
ARDGLVEASGA
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
WMGSGPLT
G
L
A
E
I
QLPDLQPGSSIMPGKVNPV
L
P
E
A
V
T
Q
V
A
A
Q
V
IGND
A
A
I
A
WGGANG
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
GLTA
N
V
E
H
L
R
R
L
A
ESSP
S
I
V
TP
L
N
S
AI
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
DRGLIGDRL
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
QLDSDRL
29
PsiBlast_CBE
98.68
99%
-90
- C3 -
4APB
4
FUMC_MYCTU
B:
[9-468]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
C
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
Q
------
27
PsiBlast_CBE
97.77
99%
-90
- C3 -
4APB
4
FUMC_MYCTU
D:
[9-470]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
C
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
Q
L
D
----
4
PsiBlast_PDB
97.50
99%
-89
- C3 -
4APB
4
FUMC_MYCTU
A:
[9-468]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
C
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
Q
------
28
PsiBlast_CBE
97.49
99%
-89
- C3 -
4APB
3
FUMC_MYCTU
C:
[9-468]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
C
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
Q
------
2
PsiBlast_PDB
97.19
100%
-89
- C3 -
4ADL
2
FUMC_MYCTU
A:
[31-489]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
-------
26
PsiBlast_CBE
97.04
100%
-90
- C3 -
4ADL
2
FUMC_MYCTU
B:
[31-488]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
--------
3
PsiBlast_PDB
96.69
100%
-91
- C3 -
4ADM
3
FUMC_MYCTU
A:
[31-489]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
---------
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
-------
73
HHSearch
96.66
100%
-92
- C3 -
4ADM
3
FUMC_MYCTU
A:
[31-489]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
-
S
E
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
---------
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
-------
22
PsiBlast_CBE
96.59
100%
-90
- C3 -
4ADM
2
FUMC_MYCTU
C:
[32-487]
---------
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
---------
21
PsiBlast_CBE
96.43
100%
-91
- C3 -
4ADM
2
FUMC_MYCTU
D:
[32-487]
---------
Y
R
I
E
H
-----
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
---------
25
PsiBlast_CBE
96.37
100%
-88
- C3 -
4ADL
1
FUMC_MYCTU
C:
[31-489]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
-------
24
PsiBlast_CBE
96.25
100%
-88
- C3 -
4ADL
1
FUMC_MYCTU
D:
[31-489]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
E
-------
23
PsiBlast_CBE
95.81
100%
-90
- C3 -
4ADM
3
FUMC_MYCTU
B:
[31-488]
--------
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
---------
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
R
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
--------
1
PsiBlast_PDB
95.56
100%
-89
- C3 -
3NO9
-
FUMC_MYCTU
A:
[7-466]
------
S
A
N
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
S
D
L
G
L
L
A
P
E
K
A
D
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
K
------
G
-
G
--
V
-----
T
L
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
A
-
H
L
I
P
A
L
Q
Q
L
H
D
A
L
A
A
K
A
L
D
W
H
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
C
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
D
D
F
G
V
R
V
V
A
V
L
V
A
Q
T
G
L
S
E
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
------
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
K
L
L
T
N
V
S
R
L
F
A
Q
R
C
I
A
G
L
T
A
N
V
E
H
L
R
R
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
-
L
S
I
E
D
L
D
R
R
L
D
V
L
A
M
A
K
A
--------
30
PsiBlast_CBE
94.97
85%
-91
- C3 -
3RRP
4
?
B:
[11-469]
---------
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
E
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
K
D
L
G
L
L
A
A
E
K
A
D
A
I
I
A
A
A
Q
E
I
A
D
G
K
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
A
N
E
V
I
A
S
I
A
A
Q
------
A
-
T
P
P
V
-----
V
V
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
L
A
A
T
E
A
A
V
R
-
D
L
I
P
A
L
E
Y
L
Q
Q
A
L
A
T
K
A
K
A
W
K
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
G
G
Y
A
R
Q
I
E
A
G
I
E
R
V
K
A
T
L
P
R
L
G
E
L
P
I
G
G
T
A
V
G
T
G
L
N
A
P
D
G
F
G
A
K
V
V
E
V
L
K
Q
S
T
G
L
S
E
-
L
K
T
A
S
D
S
F
E
A
Q
A
A
R
D
G
L
V
E
G
S
G
A
L
K
T
I
A
A
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
G
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
T
V
G
G
L
S
G
A
F
E
L
N
V
Y
I
P
V
M
A
R
N
L
L
E
S
F
T
L
L
A
N
V
S
R
L
F
V
D
K
C
V
D
G
L
V
A
N
E
D
H
L
R
T
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
E
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
K
L
S
I
E
E
L
D
K
R
L
D
V
L
A
M
A
K
V
--------
7
PsiBlast_PDB
94.32
85%
-91
- C3 -
3RRP
3
?
A:
[11-470]
---------
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
A
E
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
K
D
L
G
L
L
A
A
E
K
A
D
A
I
I
A
A
A
Q
E
I
A
D
G
K
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
A
N
E
V
I
A
S
I
A
A
Q
------
A
-
T
P
P
V
-----
V
V
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
L
A
A
T
E
A
A
V
R
-
D
L
I
P
A
L
E
Y
L
Q
Q
A
L
A
T
K
A
K
A
W
K
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
G
G
Y
A
R
Q
I
E
A
G
I
E
R
V
K
A
T
L
P
R
L
G
E
L
P
I
G
G
T
A
V
G
T
G
L
N
A
P
D
G
F
G
A
K
V
V
E
V
L
K
Q
S
T
G
L
S
E
-
L
K
T
A
S
D
S
F
E
A
Q
A
A
R
D
G
L
V
E
G
S
G
A
L
K
T
I
A
A
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
G
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
I
T
V
G
G
L
S
G
A
F
E
L
N
V
Y
I
P
V
M
A
R
N
L
L
E
S
F
T
L
L
A
N
V
S
R
L
F
V
D
K
C
V
D
G
L
V
A
N
E
D
H
L
R
T
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
E
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
K
L
S
I
E
E
L
D
K
R
L
D
V
L
A
M
A
K
V
K
-------
6
PsiBlast_PDB
93.52
87%
-87
- C3 -
3RD8
-
?
A:
[8-465]
---------
Y
R
I
E
H
D
T
M
G
E
V
R
V
P
K
D
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
F
R
--
G
L
E
R
T
Q
I
R
A
L
G
L
L
K
A
A
C
A
Q
V
N
K
D
L
G
L
L
D
P
E
K
A
D
A
I
I
A
A
A
G
E
I
A
E
G
K
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
A
A
------
N
-
G
--
V
-----
T
V
H
P
N
D
H
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
R
-
H
L
I
P
A
L
E
V
L
H
A
S
L
A
A
K
A
K
Q
W
R
T
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
G
G
Y
A
R
Q
I
E
A
G
I
E
R
V
K
A
T
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
E
G
F
G
A
K
V
V
E
V
L
V
N
E
T
G
L
A
E
-
L
R
T
A
V
D
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
Q
P
G
S
S
I
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
C
Q
V
V
G
N
D
A
A
I
A
F
G
G
A
S
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
L
L
E
S
F
T
L
L
S
N
V
S
R
L
F
A
E
R
C
I
D
G
L
V
A
N
E
E
R
L
R
E
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
K
V
A
K
Q
A
L
A
E
K
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
--
L
S
L
E
E
L
D
R
R
L
D
V
L
A
M
A
R
V
K
-------
5
PsiBlast_PDB
93.08
92%
-91
- C3 -
3QBP
-
?
A:
[26-472]
--------------------
R
V
P
A
K
A
L
W
R
A
Q
T
Q
R
A
V
E
N
F
P
I
S
G
R
--
G
L
E
R
A
Q
I
R
A
L
G
L
L
K
G
A
C
A
Q
V
N
M
D
L
G
L
L
A
P
E
K
A
E
A
I
I
A
A
A
A
E
I
A
D
G
Q
H
D
D
Q
F
P
I
D
V
F
Q
T
G
S
G
T
S
S
N
M
N
T
N
E
V
I
A
S
I
A
G
A
------
N
-
G
--
V
-----
A
V
H
P
N
D
D
V
N
M
S
Q
S
S
N
D
T
F
P
T
A
T
H
I
A
A
T
E
A
A
V
S
-
H
L
I
P
A
L
E
I
L
Q
D
A
L
A
T
K
A
L
E
W
Q
S
V
V
K
S
G
R
T
H
L
M
D
A
V
P
V
T
L
G
Q
E
F
S
G
Y
A
R
Q
I
E
A
G
I
E
R
V
R
A
T
L
P
R
L
G
E
L
A
I
G
G
T
A
V
G
T
G
L
N
A
P
E
G
F
G
V
K
V
V
S
V
L
V
S
Q
T
G
L
P
Q
-
L
R
T
A
A
N
S
F
E
A
Q
A
A
R
D
G
L
V
E
A
S
G
A
L
R
T
I
A
V
S
L
T
K
I
A
N
D
I
R
W
M
G
S
G
P
L
T
G
L
A
E
I
Q
L
P
D
L
------
M
P
G
K
V
N
P
V
L
P
E
A
V
T
Q
V
A
A
Q
V
I
G
N
D
A
A
V
A
W
G
G
A
N
G
A
F
E
L
N
V
Y
I
P
M
M
A
R
N
I
L
E
S
F
T
L
L
T
N
V
S
K
L
F
A
Q
R
C
I
A
G
L
T
A
N
A
E
H
L
R
E
L
A
E
S
S
P
S
I
V
T
P
L
N
S
A
I
G
Y
E
E
A
A
A
V
A
K
Q
A
L
K
E
R
K
T
I
R
Q
T
V
I
D
R
G
L
I
G
D
K
L
S
L
E
E
L
D
R
R
L
D
V
L
A
M
A
K
V
E
-------
74
HHSearch
84.12
52%
-82
- C3 -
3E04
3
FUMH_HUMAN
A:
[29-489]
--------
S
F
R
I
E
Y
D
T
F
G
E
L
K
V
P
N
D
K
Y
Y
G
A
Q
T
V
R
S
T
M
N
F
K
I
G
G
V
TE
R
M
P
T
P
V
I
K
A
F
G
I
L
K
R
A
A
A
E
V
N
Q
D
Y
G
L
D
P
-
K
I
A
N
A
I
M
K
A
A
D
E
V
A
E
G
K
L
N
D
H
F
P
L
V
V
W
Q
T
G
S
G
T
Q
T
N
M
N
V
N
E
V
I
S
N
R
A
I
E
M
L
GGEL
G
S
K
--
I
-----
P
V
H
P
N
D
H
V
N
K
S
Q
S
S
N
D
T
F
P
T
A
M
H
I
A
A
A
-
I
E
V
H
E
V
L
L
P
G
L
Q
K
L
H
D
A
L
D
A
K
S
K
E
F
A
Q
I
I
K
I
G
R
T
H
T
Q
D
A
V
P
L
T
L
G
Q
E
F
S
G
Y
V
Q
Q
V
K
Y
A
M
T
R
I
K
A
A
M
P
R
I
Y
E
L
A
A
G
G
T
A
V
G
T
G
L
N
T
R
I
G
F
A
E
K
V
A
A
K
V
A
A
L
T
G
L
-
P
-
F
V
T
A
P
N
K
F
E
A
L
A
A
H
D
A
L
V
E
L
S
G
A
M
N
T
T
A
C
S
L
M
K
I
A
N
D
I
R
F
L
G
S
G
P
R
S
G
L
G
E
L
I
L
P
E
N
E
P
G
-----
G
K
V
N
P
T
Q
C
E
A
M
T
M
V
A
A
Q
V
M
G
N
H
V
A
V
T
V
G
G
S
N
G
H
F
E
L
N
V
F
K
P
M
M
I
K
N
V
L
H
S
A
R
L
L
G
D
A
S
V
S
F
T
E
N
C
V
V
G
I
Q
A
N
T
E
R
I
N
K
L
M
N
E
S
L
M
L
V
T
A
L
N
P
H
I
G
Y
D
K
A
A
K
I
A
K
T
A
H
K
N
G
S
T
L
K
E
T
A
I
E
L
G
----
Y
L
T
A
E
Q
F
D
E
W
V
K
P
K
D
M
L
G
P
--------
9
PsiBlast_PDB
83.69
53%
-79
- C3 -
3TV2
2
?
A:
[1-443]
----------
R
M
E
R
D
T
F
G
E
I
A
V
P
A
A
R
L
W
G
A
Q
T
Q
R
S
L
Q
N
F
K
I
S
T
E
--
K
Q
S
P
E
L
I
H
A
L
A
L
I
K
R
A
A
A
A
V
N
L
E
L
G
V
L
A
Q
D
K
A
N
A
I
V
A
A
A
D
E
I
I
A
G
R
H
A
D
E
F
P
L
A
V
W
Q
T
G
S
G
T
Q
T
N
M
N
L
N
E
V
I
A
N
R
A
S
E
L
L
----
G
-
G
--
E
RGESR
A
V
H
P
N
D
D
V
N
R
G
Q
S
S
N
D
V
F
P
T
A
M
H
I
A
A
A
R
A
I
V
D
-
H
L
L
P
A
L
R
T
L
R
A
T
L
D
A
K
A
A
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
F
S
G
Y
V
A
Q
L
D
Q
G
I
R
H
V
E
A
A
L
P
H
L
Y
E
L
A
Q
G
G
T
A
V
G
T
G
L
N
A
H
P
K
F
A
A
G
V
A
A
E
I
G
R
L
T
G
L
P
--
F
V
S
A
P
N
K
F
E
V
M
A
A
A
D
A
L
V
F
A
H
G
A
L
K
T
V
A
A
S
L
M
K
I
A
N
D
I
R
W
L
A
S
G
P
R
C
G
L
G
E
L
S
I
P
E
N
E
P
G
S
S
I
M
P
G
K
V
N
P
T
Q
S
E
A
V
T
M
L
C
C
Q
V
F
G
N
D
V
A
V
N
F
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
I
A
H
N
V
L
Q
S
V
R
L
L
A
D
G
A
Q
G
F
N
D
H
C
A
V
G
I
E
P
N
R
A
R
I
D
A
L
L
N
E
S
L
M
L
V
T
A
L
N
P
H
I
G
Y
D
K
A
A
Q
I
A
K
K
A
H
K
E
G
T
T
L
K
A
A
A
L
A
L
G
Y
V
T
D
---------------------------
14
PsiBlast_PDB
79.93
51%
-71
- C3 -
1FUO
2
FUMC_ECOLI
A:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
G
S
S
I
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
13
PsiBlast_PDB
79.67
51%
-69
- C3 -
1FUQ
2
FUMC_ECOLI
A:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
G
S
S
I
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
10
PsiBlast_PDB
79.63
51%
-68
- C3 -
1KQ7
2
FUMC_ECOLI
A:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
Q
P
G
S
S
I
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
18
PsiBlast_PDB
79.56
51%
-69
- C3 -
2FUS
1
FUMC_ECOLI
A:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
N
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
G
S
S
I
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
35
PsiBlast_CBE
79.06
51%
-70
- C3 -
1FUP
2
FUMC_ECOLI
B:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
----
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
34
PsiBlast_CBE
79.02
51%
-69
- C3 -
1FUQ
2
FUMC_ECOLI
B:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
----
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
12
PsiBlast_PDB
78.99
51%
-70
- C3 -
1FUP
2
FUMC_ECOLI
A:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
G
S
S
I
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
38
PsiBlast_CBE
78.84
51%
-71
- C3 -
2FUS
1
FUMC_ECOLI
B:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
R
G
MER
K
V
N
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
----
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
36
PsiBlast_CBE
78.63
51%
-71
- C3 -
1FUO
2
FUMC_ECOLI
B:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
E
P
----
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------
33
PsiBlast_CBE
78.24
51%
-70
- C3 -
1KQ7
1
FUMC_ECOLI
B:
[5-431]
----------
R
S
E
K
D
S
M
G
A
I
D
V
P
A
D
K
L
W
G
A
Q
T
Q
R
S
L
E
H
F
R
I
S
T
E
--
K
M
P
T
S
L
I
H
A
L
A
L
T
K
R
A
A
A
K
V
N
E
D
L
G
L
L
S
E
E
K
A
S
A
I
R
Q
A
A
D
E
V
L
A
G
Q
H
D
D
E
F
P
L
A
I
W
Q
T
G
S
G
T
Q
S
N
M
N
M
N
E
V
L
A
N
R
A
S
E
L
L
----
G
-
G
--
V
RGMER
K
V
H
P
N
D
D
V
N
K
S
Q
S
S
N
D
V
F
P
T
A
M
H
V
A
A
L
L
A
L
R
K
-
Q
L
I
P
Q
L
K
T
L
T
Q
T
L
N
E
K
S
R
A
F
A
D
I
V
K
I
G
R
T
H
L
Q
D
A
T
P
L
T
L
G
Q
E
I
S
G
W
V
A
M
L
E
H
N
L
K
H
I
E
Y
S
L
P
H
V
A
E
L
A
L
G
G
T
A
V
G
T
G
L
N
T
H
P
E
Y
A
R
R
V
A
D
E
L
A
V
I
T
-
C
A
P
-
F
V
T
A
P
N
K
F
E
A
L
A
T
C
D
A
L
V
Q
A
H
G
A
L
K
G
L
A
A
S
L
M
K
I
A
N
D
V
R
W
L
A
S
G
P
R
C
G
I
G
E
I
S
I
P
E
N
Q
P
----
M
P
G
K
V
N
P
T
Q
C
E
A
L
T
M
L
C
C
Q
V
M
G
N
D
V
A
I
N
M
G
G
A
S
G
N
F
E
L
N
V
F
R
P
M
V
I
H
N
F
L
Q
S
V
R
L
L
A
D
G
M
E
S
F
N
K
H
C
A
V
G
I
E
P
N
R
E
R
I
N
Q
L
L
N
E
S
L
M
L
V
T
A
L
N
T
H
I
G
Y
D
K
A
A
E
I
A
K
K
A
H
K
E
-------------------------------------------