@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Rv1537: (2016-05-02 )
MESRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARAYGARSAMPMHQARRLIGVTAVVLPPRGVVYGIASRRVFDTVRGLVPVVEQLSFDEAFAEPPQLAGAVAEDVETFCERLRRRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVRHAEEQALLSGLPVRRLWGIGPVAEEKLHRLGIETIGQLAALSDAEAANILGATIGPALHRLARGIDDRPVVERAEAKQISAESTFAVDLTTMEQLHEAIDSIAEHAHQRLLRDGRGARTITVKLKKSDMSTLTRSATMPYPTTDAGALFTVARRLLPDPLQIGPIRLLGVGFSGLSDIRQESLFADSDLTQETAAAHYVETPGAVVPAAHDATMWRVGDDVAHPELGHGWVQGAGHGVVTVRFETRGSGPGSARTFPVDTGDISNASPLDSLDWPDYIGQLSVEGSAGASAPTVDDVGDR

Atome Classification :

(32 SA) -----------------------------------------------------------------.........10........20........30....-.-.--------------------------------..----40........50........60........70....-------.-...80........90........100.......110.....----.-------------------.120-------------.----------------------------------------------------...------...------..130.......140.......150.......160......--.170.......-180.......190.-......200.......210.......220.......230.......240.......250....--...260.......270.......280-.----.--.......290....---------.------..300-.......--.-----.310.---......320...---....---330----........340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) -----------------------------------------------------------------MESRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGG-L-G--------------------------------GR----GVVAGASYEARAYGARSAMPMHQARRLIGVTAVVLP-------P-RGVVYGIASRRVFDTVRGLVPVVEQLSFDEAFAEPPQLAGA----V-------------------AE---------------D----------------------------------------------------VET------FCE------RLRRRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVR--HAEEQALLSGL-PVRRLWGIGPVAEE-KLHRLGIETIGQLAALSDAEAANILGATIGPALHRLARGIDDRPVVERAEAKQISAESTFAVD--LTTMEQLHEAIDSIAEHAHQRLLR---D----G--RGARTITVKLKKSD---------M------STL---TRSATMP--Y-----PTTDA---GALFTVARRLLP---DPLQ---IG-----PIRLLGVGFSGLSDIRQESLFADSDLTQETAAAHYVETPGAVVPAAHDATMWRVGDDVAHPELGHGWVQGAGHGVVTVRFETRGSGPGSARTFPVDTGDISNASPLDSLDWPDYIGQLSVEGSAGASAPTVDDVGDR
65 Fugue 93.6127%-100 - C2 -2OH2 POLK_HUMAN A:[15-499] KEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGS-------------------------------------M----SMLSTSNYHARRFGVRAAMPGFIAKRLCP-QLIIVP-------P-NFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEE----RQNWPEDKRRYFIKNSVVF-GT---------------S----------------------------------------------------AQE------VVK------EIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDL-PIRKVSGIGKVTEK-MLKALGIITCTELYQQ-RALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTF-SE--INKAEEQYSLCQELCSELAQDLQK---E----R--LKGRTVTIKLKNVN---------F------EVK---TRASTVS--S-----VVSTA---EEIFAIAKELLK---TEID---ADFPHPLRLRLMGVRISSFP----------------------------------------------------------------------------------------------------------------------------
66 Fugue 92.4627% -95 - C2 -2W7O POLK_HUMAN A:[15-501] KEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGS-------------------------------------M----SMLSTSNYHARRFGVRAAMPGFIAKRLCP-QLIIVP-------P-NFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEE----RQNWPEDKRRYFIKQNSVVFGT---------------S----------------------------------------------------AQE------VVK------EIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDL-PIRKVSGIGKVTEK-MLKALGIITCTELYQ-QRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTF-SE--INKAEEQYSLCQELCSELAQDLQK---E----R--LKGRTVTIKLKNVN---------F------EVK---TRASTVS--S-----VVSTA---EEIFAIAKELLK---TEID---ADFPHPLRLRLMGVRISSFPNE--------------------------------------------------------------------------------------------------------------------------
39 HHSearch 89.7129% -96 - C2 -3GQC - REV1_HUMAN A:[416-827] -------------------------------------------------------------------QSCIMHVDMDCFFVSVGIRNRPDLKGKPVAVTS-N-RGTGRAPLRPGANPQLEWQYYQNKILKGIDSVLSR----AEIASCSYEARQLGIKNGMFFGHAKQLCP-NLQAVP-------Y-DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILA-----E-------------------TKL--------------T----------------------------------------------------PDE------FAN------AVRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLK--PEEVDDFIRGQ-LVTNLPGVGHSMES-KLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR--FTQPKEAEAFLLSLSEEIQRRLEA---T----G--MKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI---ARTVTLD--Q-----ATDNA---KIIGKAMLNMFH---TMKLN--IS-----DMRGVGIHVNQLVPT--------------------------------------------------------------------------------------------------------------------------
49 HHSearch 88.5328% -90 - C2 -4ECQ POLH_HUMAN A:[8-434] ------------------------------------------------------------------QDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQ-Y-KSW------------------------------KG----GGIIAVSYEARAFGVTRSMWADDAKKLCP-DLLLAQVRESRGKA-NLTKYREASVEVMEIMSRFA-VIERASIDEAYVDLTSAVQERLQKL-------------------QG---------------QPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAV------IVE------EMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVS--HGSVPQLFSQM-PIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTK---DRNDND--RVATQLVVSIRVQG---------D------KRLSSLRRCCALTRYD-----AHKMS---HDAFTVIKNCNTSGIQTEW---SP-----PLTMLFLCATKFSA---------------------------------------------------------------------------------------------------------------------------
42 HHSearch 87.7731% -96 - C2 -4Q45 DPO4_ECOLI F:[2-342] -------------------------------------------------------------------SRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGG-SRE--------------------------------RR----GVISTANYPARKFGVRSAMPTGMALALCP-HLTLLP-------G-RFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVH-----C-------------------HG---------------S----------------------------------------------------ATL------IAQ------EIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVIT--PAEVPAFLQTL-PLAKIPGVGKVSAA-KLEAMGLRTCGDVQACDLVMLLKRFGK-FGRILWERSQGIDERDVNSERLRKSVGVERTMAED--IHHWSECEAIIERLYPELERRLAK---V----KPDLLIARQGVKLKFDD---------F------QQT---TQ--EHV--W-----PRLNK---ADLIATARKTWD---ERRG---GR-----GVRLVGLHVTLLDP---------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 83.7232% -88 - C2 -4IRK DPO4_ECOLI A:[2-319] -------------------------------------------------------------------SRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSR-E--------------------------------RR----GVISTANYPARKFGVRSAMPTGMALALCP-HLTLLP-------G-RFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLD-----------V-------------------TD---------------S----------------------------------------------------VHCHGSATLIAQ------EIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVIT--PAEVPAFLQTL-PLAKIPGVGKVSAA-KLEAMGLRTCGDVQACDLVMLLKRFG-KFGRILWERSQGIDERDVNSERLRKSVGVERTMAED--IHHWSECEAIIERLYPELERRLAKVKPD----L--LIARQ-GVKLKFDD---------F------QQT---TQEHV----W-----PRLNK---ADLIATARK-------------------------------------------------------------------------------------------------------------------------------------------------------------
41 HHSearch 83.3628%-100 - C2 -4TQR DPO4_SULSO A:[2-341] ---------------------------------------------------------------------IVLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-SGRFE----------------------------DS----GAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVR-----D-------------------YR---------------E----------------------------------------------------AYN------LGL------EIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRT-RVRKSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKLDK---R----I----PKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISK----ETAYSESVKLLQ---KILEED-ER-----KIRRIGVRFSKFI----------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 83.3428% -93 - C2 -4G3I DPO4_SULSO A:[1-341] -------------------------------------------------------------------SMIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRRIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 83.3128% -94 - C2 -2UVU DPO4_SULSO A:[9-346] ----------------------------------------------------------------------VLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRAIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
46 HHSearch 83.2925% -99 - C2 -3OSN POLI_HUMAN A:[26-414] ------------------------------------------------------------------SSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQ-------------------------------------K----YLVVTCNYEARKLGVKKLMNVRDAKEKCP-QLVLVN-------GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEK----RLQQLQSDELSAVTVSGHV-YNNQSINLLDVLHIRLLV----------------------------------------------------GSQ------IAA------EMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLL--PESCQHLIHSLNHIKEIPGIGYKTAK-CLEALGINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKK---CSSEVEAKNKIEELLASLLNRVCQ---D----G--RKPHTVRLIIRRYSSEKH-----Y------GRE---SRQCPIP--SHVIQK----YDVMTPMVDILMKLFR---NMVNVKMPF-----HLTLLSVCFCNLK----------------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 83.1828% -93 - C2 -3T5H DPO4_SULSO A:[3-340] ----------------------------------------------------------------------VLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRRIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 82.9928% -94 - C2 -2ASJ DPO4_SULSO A:[11-348] ----------------------------------------------------------------------VLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRRIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
34 PsiBlast_CBE 82.9232% -87 - C2 -4IRD DPO4_ECOLI F:[2-319] -------------------------------------------------------------------SRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSR-E--------------------------------RR----GVISTANYPARKFGVRSAMPTGMALALCP-HLTLLP-------G-RFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLD-----------V-------------------TD---------------S----------------------------------------------------VHCHGSATLIAQ------EIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVIT--PAEVPAFLQTL-PLAKIPGVGKVSAA-KLEAMGLRTCGDVQACDLVMLLKRFG-KFGRILWERSQGIDERDVNSERLRKSVGVERTMAED--IHHWSECEAIIERLYPELERRLAKVKPD----L--LIARQ-GVKLKFDD---------F------QQT---TQEHV----W-----PRLNK---ADLIATARK-------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 82.8631% -90 - C2 -4R8U DPO4_ECOLI A:[1-318] -------------------------------------------------------------------SRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSR-E--------------------------------RR----GVISTANYPARKFGVRSAMPTGMALKLCP-HLTLLP-------G-RFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLD-----------V-------------------TD---------------S----------------------------------------------------VHCHGSATLIAQ------EIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVIT--PAEVPAFLQTL-PLAKIPGVGKVSAA-KLEAMGLRTCGDVQKCDLVMLLKRFG-KFGRILWERSQGIDERDVNSERLRKSVGVERTMAED--IHHWSECEAIIERLYPELERRLAKVKPD----L--LIARQ-GVKLKFDD---------F------QQT---TQEHV----W-----PRLNK---ADLIATARK-------------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 82.8628% -96 - C2 -4FBU DPO4_SULSO A:[3-340] ----------------------------------------------------------------------VLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRRIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 82.8428% -92 - C2 -3T5L DPO4_SULSO A:[3-340] ----------------------------------------------------------------------VLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRRIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 82.8028% -96 - C2 -2ASL DPO4_SULSO A:[11-348] ----------------------------------------------------------------------VLFVDFDYFYAQVEEVLNPSLKGKPVVVCV-F-S--------------------------------GRFEDSGAVATANYEARKFGVKAGIPIVEAKKILP-NAVYLP-------M-RKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLD-----------I-------------------SD---------------K----------------------------------------------------VRD------YREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVID--DEEVKRLIREL-DIADVPGIGNITAE-KLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVR-KSIGRIVTMKRN--SRNLEEIKPYLFRAIEESYYKL-----D----K--RIPKAIHVVAVTED---------L------DIV---SRGRTFP--H-----GISKE---TA-YSESVKLLQ---KILE---EDER---KIRRIGVRFSKF-----------------------------------------------------------------------------------------------------------------------------
32 PsiBlast_CBE 82.6332% -91 - C2 -4IRK DPO4_ECOLI B:[2-319] -------------------------------------------------------------------SRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSR-E--------------------------------RR----GVISTANYPARKFGVRSAMPTGMALALCP-HLTLLP-------G-RFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLD-----------V-------------------TD---------------S----------------------------------------------------VHCHGSATLIAQ------EIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVIT--PAEVPAFLQTL-PLAKIPGVGKVSAA-KLEAMGLRTCGDVQACDLVMLLKRFG-KFGRILWERSQGIDERDVNSERLRKSVGVERTMAED--IHHWSECEAIIERLYPELERRLAKVKPD----L--LIARQ-GVKLKFDD---------F------QQT---TQEHV----W-----PRLNK---ADLIATARK-------------------------------------------------------------------------------------------------------------------------------------------------------------