@TOME V2.3
(Nov 2016)

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3D Common Core:

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Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Rv1582c: (2016-05-03 )
MADIPYGTDYPDAPWIDRDGHVLIDDGGKPTQVHRGQARIAYRLAERYQDKLLHVAGIGWHSWDGRRWAADDRGEAKRAVLAELRQALSDSLNDKELRADVRKCESASGVAGVLDLAAALVPFAATVADLDSDPHLLNVANGTLDLHTLKLRPHAPADRITKICRGAYQSDTESPLWQAFLTRVLPDEGVRGFVQRLAGVGLLGTVREHVLAILIGVGANGKSVFDKAIRYALGDYACTAEPDLFMHRENAHPTGEMDLRGVRWVAVSESEKDRRLAESTIKRLTGGDTIRARKMRQDFVEFTPSHTPLLITNHLPRVPGDDTAIWRRIRVVPFEVVIPADEQDRELDARLQLEADSILSWAVAGWSDYQRIGLSQPDAVLAATSNYREDSDTIKRFIDDECVTSSPVLKATTTHLFEAWQRWRVQEGVPEISRKAFGQSLDTHGYPVTDKARDGRWRAGIAVRGADDFDD

Atome Classification :

(20 SA) -------------------------------------------------------.......------..10...------------.....20........-------30........40........----50......--..60..-----......70..-------.....----.80...---.....90...-------.....100.-----------......110-----....-------------...120.......130.------------------.--.....140......-------.-------150----.......160.......170.....-----..180-------...----------..-...190....-..--------------.-200...-------....210-----.......220..-----......230-------..-..-------..--.240-----.--.-----.....-.------250-..-..---.....260.......-270.-----...-----------..-.280--------...-...-.-290........300--..-......310.-......320----.---------------.------------------------......-330...--------------.-...--.340...----....350----....-------....360-....---...370.....--.------..380..-....-----.390....-----...------400-------...------------....-------.----.410---.........420.-----....--------.----.-430..-.....-440.----......-450---...----------.....460..--------.....470-
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) -------------------------------------------------------MADIPYG------TDYPDAP------------WIDRDGHVLIDDGGK-------PTQVHRGQARIAYRLAERYQ----DKLLHVAG--IGWHSW-----DGRRWAADDR-------GEAKR----AVLAEL---RQALSDSLND-------KELRADVRK-----------CESASGVAG-----VLDL-------------AAALVPFAATVADLDSD------------------P--HLLNVANGTLDLHT-------L-------KLR----PHAPADRITKICRGAYQSDTESPLW-----QAFL--------TRV----------LP-DEGVRGFVQR-LA--------------G-VGLLGT-------VREHVLA-----ILIGVGANG-KS-----VFDKAIRYA-------LG-DY-------AC--TAE------P--D-----LFMHR-E------N---AH-PT---GEMDLRGVRWVAVSE-SEKD-----RRL-----------AE-STIK--------RLT-GGD-T-I-RARKMRQDFVE---FT-PSHTPLLITN-HLPRVPGD-----D---------------T------------------------AIWRRI-R-VVPF--------------E-VVI--PADEQDR----ELDARL-----QLEA-------DSILSWA-VAGW---SDYQR-IGLSQ--P------DAVLAAT-SNYR-----EDSDTIKR-----FID------D---------ECV------------TSSP-------V----LK-----ATTTHLFEAWQRW-----RVQE--------G----V-PEISR-KAFGQ-SLDT----HGYPVT-DK----ARD----------GRWRAGIAVR--------GADDFDD--
25 Fugue 77.9420% -11 - C3 -4US3 ? A:[10-450] -----------------------------------------------------------------------GREQ------------WASRLGFILAAMGSA-------VG--LGNIWRFSYVTGENGG----AAFLLVYL--GFIALI------------------------GIP----IVLAEFTIGRRAQSDAVGS-------FEKLAP-GK-----------PWKVAGLMG-----VAAG-------------FLILSFYGVIAGWILF----------------------YLFNYITGQL--------------------------WSAPAEGFGGFFEGFIANPTLPLFW-----QALF--------MIA----------TI-WIVAIGVKKG-IE--------------R-SNKILM-------PLLGVLL-----IALAIYSLT-LG-----GAKEGLAFL-------FSPDW-------SA--LKD------P--G-----VYLAAIS------Q---AF-FT---LSLGM-GALITYGSY-VSKD-----SRL-----------PG-AAVSVA------GLD-TAF-A-I-IAGIMIFPAVFALGLS-PSGGPGLVFV-VLPDIFDS------------------------------------------------IRLG-P-IVGI--------------A-FFI--LLGAAAL----SSAVSL------LEV-------PVAYFMR-KFDW---SRKQAAITLGV--I------ITLLGIP-SSLS-----FGVLGEVT-----IIP------G---------LNI------------FDSV-------D----FI-----ASSVFLPLGGMII-----ALFI--------G----W-GWKTS-DALAE-SDLT----DSVWGK-LW----ILS----------LRFIAPIAIL--------IVFLSAF--
31 Fugue 75.7217% -16 - C3 -2J7U A:[8-618] MDVIGERIKRIKEEHNSTWHYDDENPYKTWAYHGSYEVSSMINGVVKLLTKPWDVVPMVTQM------AMTDTTP------------FGQQRVFKEKVDTRT-------P-RPLPGTRKVMEITAEWLW----RTLGRNKR--PRLCTR-----EEFTKKVRTN-------DSAKA----AVEDEE---FWKLVDRERE-------LHKLGKCGS-----------CVS--RAIW-----YMWL-------------GARYLEFEAL--GFLNE------------------D--HWFSRENSYSGVEG-------E-------GLH----KLGYILRDISKIPGGAMYADDTAGW-----DTRI--------TEDDLHNEEKIIQQM-DPEHRQLANA-IF--------------K-LTYQNK-------VVKVQRPTPTGTVMDIISRKD-QR-----GSGQVGTYG-------LN-TF-------T---NME------A--Q-----LVRQM-E------G---EG-VL---TKADLENPHLLEKKI-TQWL-----ETK-----------GV-ERLK--------RMAISGD-D-C-VVKPIDDRFAN----------ALLALN-DMGKVRKDIPQWQP---------------S------------------------KGWHDW-Q-QVPFCSHHFHELIMKDGRK-LVV--PCRPQD-----ELIGRA-----RISQ-------GA--------GW---SLRET-ACLGK--A------YAQMWSLMYFHR-----RDLRLASN-----AIC------SAVPVHWVPTSRT------------TWSI-------H----AHHQW--MTTEDMLTVWNRV-----WIEENPWMEDKTP----V-TTWENVPYLGK-REDQ----WCGSLI-GL----TSR----------ATWAQNIPTAIQQVRSLIGNEEFLDYM
27 Fugue 70.9914% -37 - C3 -2O1U ? A:[34-661] ----------------------------MMKLIINSLYKNKEIFLRELISNASDALDKIRLI------SLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTVGFYSAFLVADKVI----VTSKHNNDTQHIWESD-----SNEFSVIADP-------RGNTLGRGTTITLVL---KEEASDYLEL-------DTIKNLVKKYSQFINFPIYVWSSKVWDWE-----LMNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDD------------------PMAYIHFTAEGEVTFKS-------I-------LFV----PTSAPRYIKLYVRRVFITDDFHDMM-----PKYLNFVKGVVDSDD----------LP-LNVSRETLQQHKL--------------L-KVIRKK-------LVRKTLD-----MIKKIADEK-YNDTFWKEFGTNIKLG-------VI-ED-------HS--NRT------RLAK-----LLRFQ-S------S---HH-PS---DITSLDQYVERMKEK-QDKI-----YFM-----------AG-SSRK--------EAE-SSP-F-V-ERLLKKGYEVI---YL-TEPVDEYCIQ-ALPEFDG--------------------------------------------------KRF-Q-NVAK--------------EGVKF--DESEKTK----ESREAI-----EKEF-------EPLLNWM-KDKALK-DKIEK-AVVSQRLT------ESPCALV-ASQY-----GWSGNMER-----IMK------A---------QAYQTGKDISTNYYASQKK-------T----FEINPRHPLIKDMLRRVKED-----EDDK--------T----V-SDLAV-VLFET-ATLR----SGYLLP-DT----KAY----------GDRIERMLRL--------SLNI-----
26 Fugue 64.3112% -18 - C3 -1DPG G6PD_LEUME A:[1-485] -------------------------------------------------------V---------------------------------SEIKTLVTFFGGT-------GDLAKRKLYPSVFNLYKKGYL---QKHFAIVG--TARQAL-----NDDEFKQLVRDCIKDFTD--DQ----AQAEAF---IEHFSYRAHDVTDAASYAVLKEAIEE-----------AADKFDIDGNR---IFYM-------------SVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGT--SYDTAAELQNDLENAFDDNQLF-------RID----HYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQ--------VTL----------SE-VLGVEERAGY-YD--------------T-AGALLDM------IQNHTMQ-----IVGWLAMEKPES-----FTDKDIRAA-------KN-AA-------FN--ALK------I----------YDE-A------E---VN-KY---FVRAQYGAGDSA-----DFK-----PYL-----------EE-LDVP--------ADS-KNN-T-F-IAGELQFDLPR---W---EGVPFYVRS-G-KRLAAK-----Q---------------T------------------------RVDIVF-K-AGTF--------------N-FGS--EQEAQEA----VLSIII-----DPKG-------AIELKLN-AKSV---EDAFN-TRTID--L------GWTVSDE-DKKN------TPEPYER-----MIH------D---------TMN------------GDGS-------N----F---------ADWNGVSIAW-----KFVD--------A----I-SAVYT-ADKAPLETYK----SGSMGP-EA----SDK----------LLAANGDAWV--------FKG------
24 Fugue 58.5310% -25 - C3 -3KHK ? A:[7-530] ---------------------------------------------------------------------QQFLND------------LDNQLWRAADKLRSN-------LDAANYKHVVLGLIFLKYVS----DAFEERQQ--ELTELF-----QKDDDDNIYY-------LPRED----YDSDEA---YQQAIAEELE-------IGDYYTEKN-----------VFWVPKTAR-----WNKL-------------RDVITLPTSVSWLIDNA------------------F--DDIEKANPKLKGIL-------N-------RIS----QYQLDADKLIGLINEFSKDILGHVY-----EYFL--------GQF----------AL-AEGKQG------------------------GQYYT-------PKSIVTL-----IVEMLEPYK-GR-----VYD--PAMG-------SG-GF-------FV--SSD------K--F-----IEKHA-N------V---KH-YN---ASEQKKQISVYGQES-NPTT-----WKL-----------AA-MNMVIRGIDFNFGKK-NAD-S-F-LDDQHPDLRAD---FV-MTNPPFNMKDWWHEKLADD-----P---------------RWTINTNKRILTPPTGNANFAWMLHMLYHLA-P-TGSM--------------A-LLL--ANGSMSSNTNNEGEIRK-----TLVE-------QDLVE-C-MVAL---PGQLF-TNTQI--P------ACIWFLT-KDKN-----AKNGKRDRRGQVLFIDARKLGYM---------KDR------------VLRD-------F----KD-----EDIQKLADTFHNW-----QQEW--------SEENNQ-AGFCF-SADLA-LIRK----NDFVLT-PG----RYV----------G--------------------------
4 HHSearch 57.8012% -43 - C2 -1U0J REP68_AAV2S A:[23-256] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQASY------------------I--SFNAASNSRSQIKA-------ALDNAGKIMSL----TKTAPDYLVGQQPV--EDISSNRIY-----KILE--------LNG----------YD-PQYAASVFLG-WA--------------T-K----K-------FGKRNTI-----WLFGPATTG-KT-----NIAEAIAHT-------VP-FY-------GC--VNW------T-------------------------NE-NF---PFNDCVDKMVIWWEE--GKM-----TAK-----------VV-ESAK--------AIL-GGS-K-V-RV------SAQ---ID-PTPVIVTSNT-NMCAVIDG-----NSTTFEHQ--------Q------------------------PLQDRM-F-KFEL--------------T-RRL--DHD---------FGKVT-----KQEV-------KDFFRWA-KDHV---VE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 Fugue 55.1119% -23 - C3 -4N7R - GLUBP_ARATH C:[55-306] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STHK------------------P--FPAEVSRSIMELSS-------V-------GTL----STLTHDGWPLGVGVRFAVDKDGTPV-----LCLN--------RSV----------SP-DKRSALHVQ--LE--------------Q-CGL-----------RTPQCT-----IQGSIGRPG-DD-----TVLKRLSAT-------WR-EK-------FGEEVKE------D--S-----LYVVA-V------D---RV-LQ---MEDFMEDGIWVASSD-YKNASPDPLRDI-----------AE-DIVN--------QIN-ANN-M-E-DIFRFCNVYVDLD-FV-VSETKMIWMD-RL----GF-----D---------------L------------------------RVWSPR-G-VYDV--------------R-IPF--PMEVTD-----EKGAKS-----SFNG-------MSQLAWE-VEKSYCPADFNK-VKLLK--Q------VV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 HHSearch 54.7917% -40 - C2 -5C3C ? A:[47-197] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIPM-----MLKGPTGCG-KS-----RFVEHMAWK-------LN-RP-------LI--TIACNEDMTA--S-----DLVGR-----------------DGPLTVAARIGAICYLDE-IVEA-----RQD-----------TI-VVIH--------PLT-DHRRV-L-PLEK-KGELVE---AH-PDFQIVISYN-P-----DL-----K---------------Q------------------------STKQRF-G-ALDF--------------D-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 Fugue 53.4316% 3 - C1 -4YCZ - ? B:[314-1176] ------------------------------------------------SEYRYAALAKDAYQQMGTAPVTEPPQV------------ILGTEDLLSRLYDEKM------DDTLATAAAQLAALWREHVDETPFEKANYLAN--LALQIHHPLPQTLFRWLNEYHMY-----GSQVD----DILRHR---PSPACHSLFW-------QAVFIALKV-----------GDAARLLDQAGWGHVYAY-------------VNVQRAVDETIAVLESC------------------P--TLFRVRARGLLEHL-------R-------RFAEGWEIYENLNIVFDIVLGQQGAILEAA-------QDWL--------EAT----------VG-LANSESYLDR-LARAFHTAVESDFVEIGMACVFED-------NIKGVIG-----LLRGWSLPI-AA-----AVAEIASLGKWLEVDGIK-DS-------TL--VQY------A--Q-----ALADY-E------G---LS-SV---QDRDGWELSISVLGRMPERSEEMV-RDL-----------VE-HLVQ--------QLH-VDS-N-A-TVDRLWFLLNE---LGMIEFAEDTTET-YGDILARD-----SHRYGEAMWYYALAHRP------------------------NKVREVMN-LLTS--------------Y-SLIQPPANDLDD----YLYKLLNDRKNTLEQCASQDMEAAELLGKMLSGY---ASLRQ-FYDIR--PHATPLSRRKQAAT-ALISVIASSDDEDFLLA-----LLG------E---------ALV------------FVSD-------P----TL-----DQIDVLLKAIEDLQAVGSRVYN--------A----C-DEFLQ-LVLAS-APGG----SSLVAS-QL----QRSLSGTGGEDIMRRLRLGLAKD--------LAGLWLAEA
5 HHSearch 51.7413% -43 - C2 -1TUE - VE1_HPV18 A:[444-622] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDW-----RPIV--------QFL----------RYQQIEFITFLGA-LK--------------S-FLK-G--------TPKKNCL-----VFCGPANTG-KS-----YFGMSFIHF-------IQ-GA-------VI--SFV------N--S-------T---------------S-HF---WLEPLTDTKVAMLDD-ATTT-----CWT-----------YFDTYMR--------NAL-DGN-P-I-SID----PLIQ---LK-CPP-ILLTTN-IHPAKDNR-----W---------------P------------------------YLESRI-T-VFEF--------------P-NAF--PFDKNGN----PVYEIN-----DKNW-------KCFFER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14 HHSearch 50.0912% -46 - C2 -3M6A LON1_BACSU A:[88-252] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVKERILE-YL--------------A-VQKLTK-------SLKGPIL-----CLAGPPGVG-KT-----SLAKSIAKS-------LG-RK-------FV--RIS------L--G-------------------GRIIQ-GM---KKAG-KLNPVFLLDE-IDKM-----S-----------------AML--------EVL-DPE-Q-NSSFSDHYIEETF---DL-SKVLFIATAN-NLATI--------P---------------G------------------------PLRDRM-E-IINI--------------A-G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9 HHSearch 49.3214% -42 - C2 -3NBX RAVA_ECOLI X:[41-183] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GESV-----FLLGPPGIA-KS-----LIARRLKFA-------FQ-NARAFEYLMTR--FST------P--E-----EVFGP-L------S-----ERL---TSGYLPEAEIVFLDE-IWKA-----GPA-----------IL-NTLL--------TAI-NER-Q-F-RN---GAHVEK---IP-MRL-LVAASN-ELPEADSS-----L---------------E------------------------ALYDRM-LIRLWL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 HHSearch 47.9714% -34 - C2 -3PVS RARA_ECOLI A:[51-176] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSM-----ILWGPPGTG-KT-----TLAEVIARY-------AN-AD-------VE--RIS------A--VTSGVKEIRE--A------I---ER-AR---QNRNAGRRTILFVDE-VHRF-----------------------AFL--------PHI-ED-----------------------GTITFIGATT-ENPSFE-L-----N---------------S------------------------ALLSRA-R-VYLL--------------K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13 HHSearch 46.1219% -6 - C2 -1KA8 - PRIM_BPP4 A:[1-92] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DADPTFD-----FIG------Y---------LET-------------LPQTSGMYMGNASIIPR-----NYRKYLYHAYLAY-----MEAN--------G----YRNVLSL-KMFGL-GLPVMLKEYGLNYEKRH----TKQ----------GI-QTNLTLK--------EE-------
6 HHSearch 43.647% -6 - C2 -1DP7 P:[2-76] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQ-----WLL------D---------NYE-------------TAE-------G----VS-----LPRSTLYNHYLLH-----SQEQ--------K----L-EPVNA-ASFGK-LIRS----VFMGLRTRRLGTRGNS----------KYHYYGLRIK--------A--------
7 HHSearch 43.2312% -22 - C2 -1SVM LT_SV40 A:[167-299] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKKRYW-----LFKGPIDSG-KT-----TLAAALLEL-------CG-GK-------AL--NVN------L--P-----L--D-------------RL-NF---ELGVAIDQFLVVFED-VKGT-----GGESRDLPSGQGINNL-DNLR--------DYL-DGS-VKV-NLEKKHLNKRT---Q--IFPPGIVTMN-E-YSV--------P---------------K------------------------TLQARFVK-QIDF--------------R-P-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16 HHSearch 40.9111% 11 - C2 -4CR2 - PRS6B_YEAST K:[176-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-LDMQKQEIRE-AV--------------E-LPLVQADLYEQIGIDPPRGV-----LLYGPPGTG-KT-----MLVKAVANS-------TK-AA-------FI--RVN------G--S-----EFVHK-YLGEGPRMV--RD-VF---RLARENAPSIIFIDE-VDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 HHSearch 40.8710% -11 - C2 -4GDF - LT_SV40 A:[287-419] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKKRYW-----LFKGPIDSG-KT-----TLAAALLEL-------CG-GK-------AL--NVN------L--P-------LD-------------RL-NF---ELGVAIDQFLVVFED-VKGT-----GGESRDLPSGQGINNL-DNLR--------DYL-DGS-VKV-NLEKKHLNKRT---QI--FPPGIVTMN-E-Y---SV-----P---------------K------------------------TLQARFVK-QIDF--------------R-P-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 38.4635% -9 - C2 -4EMD - ? A:[211-281] --------------------------------------------------------------------------------------------------------------------------RLAE--A----DELLGALA--AG---------DARRLAP--------------------LLGNE---LQAAAVSLN--------PELRRTLRA-----------GESAGALAG-----IVSG-------------SGPTCAFLCTSAD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 37.3235% -9 - C2 -4DXL - ? A:[211-281] --------------------------------------------------------------------------------------------------------------------------RLAE--A----DELLGALA--AG---------DARRLAP--------------------LLGNE---LQAAAVSLN--------PELRRTLRA-----------GESAGALAG-----IVSG-------------SGPTCAFLCTSAD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------