@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Rv2129c: (2016-05-07 )
MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS

Atome Classification :

(27 SA) -----.........10........20........30........40--------------.---------------.------------.......50-.---..--.-------------.....60-........70........80........90....---....-100.......110.......120...-....--130.-----........140.-..----....150.......160.......170.--......180.......190....--------------...------200.......210.......220.......230.......240.......250.......260.......270.......280.......290.-
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) -----MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSK---------------S---------------E------------LAVMGAEL--G---GD--D-------------RLLTVVA-DVRDLPAMQAAAETAVERFGGIDVVVANAGIASY---GSVL-KVDPQAFRRVLDVNLLGNFHTVRATL-PALI--D--R-----RGYVLIVSSLAA-FA----APPGMAPYNMSKAGNEHFANALRLEVAH--LGVSVGSAHMSWIDTALVRDTKA--------------DLP------AFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS-
110 HHSearch 79.4828%-102 - C1 -2CFC HCDR_XANP2 A:[2-232] ----------SRVAIVTGASSGNGLAIATRFLARGDRVAALDLSA---------------E---------------T------------LEETARTH--WHAYAD--K--------------VLRVRA-DVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLH-TTPVEQFDKVMAVNVRGIFLGCRAVL-PHML--LQ-G-----AGVIVNIASVAS-LV----AFPGRSAYTTSKGAVLQLTKSVAVDYAG--SGIRCNAVCPGMIETPMTQWRLD--------------QPE------LRDQVLAR--IPQKEIGTAAQVADAVMFLAGED--------------------------------------------------------------
116 HHSearch 79.0726%-107 - C1 -3D3W DCXR_HUMAN A:[4-226] -------FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQ---------------A---------------D------------LDSLVREC-------P--G--------------IEPVCV-DLGDWEATERALG----SVGPVDLLVNNAAVALL---QPFL-EVTKEAFDRSFEVNLRAVIQVSQIVA-RGLI--ARGV-----PGAIVNVSSQCS-QR----AVTNHSVYCSTKGALDMLTKVMALELGP--HKIRVNAVNPTVVMTSMGQATWS--------------DPH------KAKTMLNR--IPLGKFAEVEHVVNAILFLLSDR--------------------------------------------------------------
119 Fugue 78.7624% -99 - C1 -1XSE DHI1_CAVPO A:[22-295] NEKFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSK---------------E---------------A------------LQKVVARC--L---ELGAA-------------SAHYIAG-SMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNR---LTFF-HGEIDNVRKSMEVNFHSFVVLSVAAM-PMLM--Q--S-----QGSIAVVSSVAG-KI----TYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSITLCILGLIDTETAIKATS--------------GIY------------------LGPASPKEECALEIIKGTALRQDEMYY-----------------VGSRWVPYLLGNPGRKIMEFLSAAEYNWDNVLSNEKLYG
10 PsiBlast_PDB 78.6927% -97 - C1 -5EJ2 ? A:[37-292] ----------GKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLA---------------E------------TADLVKDL-------D--R-------------RIVTAQV-DVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTD---GRKLHKIRDNVWQDMIDINLTGVWHTVKAGV-PHVL--SGGR-----GGSIVLTSSVGG-RK----AYPNTGHYIAAKHGVIGLMRAFAVELGP--HMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFA------PISQMMHTLPVPWVDASDISN-AVLFLASDESR--------------------------------------------------------------
21 PsiBlast_CBE 78.2136% -91 - C1 -3PGX Y4146_MYCPA D:[12-229] -------SLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICA---------------PV--------------S------------ASVTYAPA--S---PE--DLDETARLVEDQGRKALTRVL-DVRDDAALRELVADGMEQFGRLDVVVANAGVLSW---GRVW-ELTDEQWDTVIGVNLTGTWRTLRATV-PAMI--EAGN-----GGSIVVVSSSAG-LK----ATPGNGHYSASKHGLTALTNTLAIELGE--YGIRVNSIHPYSVETPMIEPE-------------------------AMMEIFARHP-------------------------------------------------------------------------------------
102 HHSearch 76.6928%-103 - C1 -4RGB ? A:[21-275] ------GSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICE---------------D---------------IDIVPYKLGTYEELEETARLV--EKT-GQ--E--------------MLFRKA-DVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLT---NPDE-RDASEALRLGLDIMLIGVWNTFQVAI-PHMK--ERGQ-----GGNLIATSSMIA-LLDLTDGRGGTDAYLTSKLAITGLVRSYALMLAA--DRIRVNGVAPTNCSTPMITENPA--------------LFKVIEENPHLVNAMSTA-LPDFPMIEPRDVSNAILFLISDA--------------------------------------------------------------
1 PsiBlast_PDB 76.4136% -91 - C1 -3PGX Y4146_MYCPA A:[12-229] -------SLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICA---------------PV--------------S------------ASVTYAPA--S---PE--DLDETARLVEDQGRKALTRVL-DVRDDAALRELVADGMEQFGRLDVVVANAGVLSW---GRVW-ELTDEQWDTVIGVNLTGTWRTLRATV-PAMI--EAGN-----GGSIVVVSSSAG-LK----ATPGNGHYSASKHGLTALTNTLAIELGE--YGIRVNSIHPYSVETPMIEPE-------------------------AMMEIFARHP-------------------------------------------------------------------------------------
28 PsiBlast_CBE 76.1232%-106 - C1 -3UVE ? C:[9-218] --------VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICK---------------PIRAGVVDTAIPASTPE------------DLAETADLVKG---HN--R-------------RIVTAEV-DVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNG---GDTLDKTSEEDWTEMIDINLAGVWKTVKAGV-PHMIAGG--R-----GGSIILTSSVGG-LK----AYPHTGHYVAAKHGVVGLMRAFGVELGQ--HMIRVNSVHPTHVKTPMLHN-------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 75.8436% -92 - C1 -3PGX Y4146_MYCPA C:[12-229] -------SLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICA---------------PV--------------S------------ASVTYAPA--S---PE--DLDETARLVEDQGRKALTRVL-DVRDDAALRELVADGMEQFGRLDVVVANAGVLSW---GRVW-ELTDEQWDTVIGVNLTGTWRTLRATV-PAMI--EAGN-----GGSIVVVSSSAG-LK----ATPGNGHYSASKHGLTALTNTLAIELGE--YGIRVNSIHPYSVETPMIEPE-------------------------AMMEIFARHP-------------------------------------------------------------------------------------
8 PsiBlast_PDB 75.2633%-100 - C1 -3TJR ? A:[26-245] -----LSGFDGRAAVVTGGASGIGLATATEFARRGARLVLSDVDQ---------------PAL-------------E------------QAVNGLRG--Q---GF--D--------------AHGVVC-DVRHLDEMVRLADEAFRLLGGVDVVFSNAGIVVA---GPLA-QMNHDDWRWVIDIDLWGSIHAVEAFL-PRLL--E--QGT---GGHIAFTASFAG-LV----PNAGLGTYGVAKYGVVGLAETLAREVKP--NGIGVSVLCPMVVETKLVSNSE-----------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 75.0036% -92 - C1 -3PGX Y4146_MYCPA B:[12-229] -------SLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICA---------------PV--------------S------------ASVTYAPA--S---PE--DLDETARLVEDQGRKALTRVL-DVRDDAALRELVADGMEQFGRLDVVVANAGVLSW---GRVW-ELTDEQWDTVIGVNLTGTWRTLRATV-PAMI--EAGN-----GGSIVVVSSSAG-LK----ATPGNGHYSASKHGLTALTNTLAIELGE--YGIRVNSIHPYSVETPMIEPE-------------------------AMMEIFARHP-------------------------------------------------------------------------------------
27 PsiBlast_CBE 74.6932%-105 - C1 -3UVE ? D:[9-218] --------VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICK---------------PIRAGVVDTAIPASTPE------------DLAETADLVKG---HN--R-------------RIVTAEV-DVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNG---GDTLDKTSEEDWTEMIDINLAGVWKTVKAGV-PHMIAGG--R-----GGSIILTSSVGG-LK----AYPHTGHYVAAKHGVVGLMRAFGVELGQ--HMIRVNSVHPTHVKTPMLHN-------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 74.6532%-106 - C1 -3UVE ? A:[9-218] --------VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICK---------------PIRAGVVDTAIPASTPE------------DLAETADLVKG---HN--R-------------RIVTAEV-DVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNG---GDTLDKTSEEDWTEMIDINLAGVWKTVKAGV-PHMIAGG--R-----GGSIILTSSVGG-LK----AYPHTGHYVAAKHGVVGLMRAFGVELGQ--HMIRVNSVHPTHVKTPMLHN-------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 74.6237%-103 - C1 -2JAP ? D:[3-192] ------SALQGKVALITGASSGIGEATARALAAEGAAVAIAARRV---------------E---------------K------------LRALGDEL--T---AA--G-------------AKVHVLELDVADRQGVDAAVASTVEALGGLDILVNNAGIMLL---GPVE-DADTTDWTRMIDTNLLGLMYMTRAAL-PHLL--R--S-----KGTVVQMSSIAG-RV----NVRNAAVYQATKFGVNAFSETLRQEVTE--RGVRVVVIEPGTTDTEL----------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 74.4137%-103 - C1 -2JAP ? A:[3-192] ------SALQGKVALITGASSGIGEATARALAAEGAAVAIAARRV---------------E---------------K------------LRALGDEL--T---AA--G-------------AKVHVLELDVADRQGVDAAVASTVEALGGLDILVNNAGIMLL---GPVE-DADTTDWTRMIDTNLLGLMYMTRAAL-PHLL--R--S-----KGTVVQMSSIAG-RV----NVRNAAVYQATKFGVNAFSETLRQEVTE--RGVRVVVIEPGTTDTEL----------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 74.3437%-101 - C1 -2JAP ? B:[3-192] ------SALQGKVALITGASSGIGEATARALAAEGAAVAIAARRV---------------E---------------K------------LRALGDEL--T---AA--G-------------AKVHVLELDVADRQGVDAAVASTVEALGGLDILVNNAGIMLL---GPVE-DADTTDWTRMIDTNLLGLMYMTRAAL-PHLL--R--S-----KGTVVQMSSIAG-RV----NVRNAAVYQATKFGVNAFSETLRQEVTE--RGVRVVVIEPGTTDTEL----------------------------------------------------------------------------------------------------------------------------
112 HHSearch 74.3229%-107 - C1 -3N74 - ? A:[1-235] ------MSLEGKVALITGAGSGFGEGMAKRFAKGGAKVVIVDRDK---------------A---------------G------------AERVAGEI--G----D--A--------------ALAVAA-DISKEADVDAAVEAALSKFGKVDILVNNAGIGHKP--QNAE-LVEPEEFDRIVGVNVRGVYLMTSKLI-PHFK--E--NGAKGQECVILNVASTGA-GR----PRPNLAWYNATKGWVVSVTKALAIELAP--AKIRVVALNPV---------------------------------------------IPMGRLLKPDDLAEAAAFLCSPQ--------------------------------------------------------------
29 PsiBlast_CBE 74.2332%-105 - C1 -3UVE ? B:[9-218] --------VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICK---------------PIRAGVVDTAIPASTPE------------DLAETADLVKG---HN--R-------------RIVTAEV-DVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNG---GDTLDKTSEEDWTEMIDINLAGVWKTVKAGV-PHMIAGG--R-----GGSIILTSSVGG-LK----AYPHTGHYVAAKHGVVGLMRAFGVELGQ--HMIRVNSVHPTHVKTPMLHN-------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 73.9537%-101 - C1 -2JAP ? C:[3-192] ------SALQGKVALITGASSGIGEATARALAAEGAAVAIAARRV---------------E---------------K------------LRALGDEL--T---AA--G-------------AKVHVLELDVADRQGVDAAVASTVEALGGLDILVNNAGIMLL---GPVE-DADTTDWTRMIDTNLLGLMYMTRAAL-PHLL--R--S-----KGTVVQMSSIAG-RV----NVRNAAVYQATKFGVNAFSETLRQEVTE--RGVRVVVIEPGTTDTEL----------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 73.4337%-101 - C1 -2JAH ? A:[3-192] ------SALQGKVALITGASSGIGEATARALAAEGAAVAIAARRV---------------E---------------K------------LRALGDEL--T---AA--G-------------AKVHVLELDVADRQGVDAAVASTVEALGGLDILVNNAGIMLL---GPVE-DADTTDWTRMIDTNLLGLMYMTRAAL-PHLL--R--S-----KGTVVQMSSIAG-RV----NVRNAAVYQATKFGVNAFSETLRQEVTE--RGVRVVVIEPGTTDTEL----------------------------------------------------------------------------------------------------------------------------
65 PsiBlast_CBE 71.0133%-101 - C1 -3PK0 ? C:[5-186] -----MFDLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRST---------------A---------------D------------IDACVADL--DQL-GS--G-------------KVIGVQT-DVSDRAQCDALAGRAVEEFGGIDVVCANAGVFPD---APLA-TMTPEQLNGIFAVNVNGTFYAVQACL-DALIA-S--G-----SGRVVLTSSITGPIT----GYPGWSHYGATKAAQLGFMRTAAIELAP--HKITV----------------------------------------------------------------------------------------------------------------------------------------
64 PsiBlast_CBE 70.0333% -99 - C1 -3PK0 ? D:[5-186] -----MFDLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRST---------------A---------------D------------IDACVADL--DQL-GS--G-------------KVIGVQT-DVSDRAQCDALAGRAVEEFGGIDVVCANAGVFPD---APLA-TMTPEQLNGIFAVNVNGTFYAVQACL-DALIA-S--G-----SGRVVLTSSITGPIT----GYPGWSHYGATKAAQLGFMRTAAIELAP--HKITV----------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 68.7036% -98 - C1 -3RIH ? C:[36-217] -----MFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSP---------------R---------------E------------LSSVTAEL--GEL-GA--G-------------NVIGVRL-DVSDPGSCADAARTVVDAFGALDVVCANAGIFPE---ARLD-TMTPEQLSEVLDVNVKGTVYTVQACLAPLTA--S--G-----RGRVILTSSITGPVT----GYPGWSHYGASKAAQLGFMRTAAIELAP--RGVTV----------------------------------------------------------------------------------------------------------------------------------------
66 PsiBlast_CBE 68.3133% -98 - C1 -3PK0 ? B:[5-186] -----MFDLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRST---------------A---------------D------------IDACVADL--DQL-GS--G-------------KVIGVQT-DVSDRAQCDALAGRAVEEFGGIDVVCANAGVFPD---APLA-TMTPEQLNGIFAVNVNGTFYAVQACL-DALIA-S--G-----SGRVVLTSSITGPIT----GYPGWSHYGATKAAQLGFMRTAAIELAP--HKITV----------------------------------------------------------------------------------------------------------------------------------------
67 PsiBlast_CBE 67.3533%-100 - C1 -3PK0 ? A:[5-186] -----MFDLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRST---------------A---------------D------------IDACVADL--DQL-GS--G-------------KVIGVQT-DVSDRAQCDALAGRAVEEFGGIDVVCANAGVFPD---APLA-TMTPEQLNGIFAVNVNGTFYAVQACL-DALIA-S--G-----SGRVVLTSSITGPIT----GYPGWSHYGATKAAQLGFMRTAAIELAP--HKITV----------------------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 66.4536% -89 - C1 -3RIH ? A:[36-217] -----MFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSP---------------R---------------E------------LSSVTAEL--GEL-GA--G-------------NVIGVRL-DVSDPGSCADAARTVVDAFGALDVVCANAGIFPE---ARLD-TMTPEQLSEVLDVNVKGTVYTVQACLAPLTA--S--G-----RGRVILTSSITGPVT----GYPGWSHYGASKAAQLGFMRTAAIELAP--RGVTV----------------------------------------------------------------------------------------------------------------------------------------
41 PsiBlast_CBE 65.5136% -88 - C1 -3RIH ? B:[36-217] -----MFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSP---------------R---------------E------------LSSVTAEL--GEL-GA--G-------------NVIGVRL-DVSDPGSCADAARTVVDAFGALDVVCANAGIFPE---ARLD-TMTPEQLSEVLDVNVKGTVYTVQACLAPLTA--S--G-----RGRVILTSSITGPVT----GYPGWSHYGASKAAQLGFMRTAAIELAP--RGVTV----------------------------------------------------------------------------------------------------------------------------------------