@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2214c: (2016-05-08 )
MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI
Atome Classification :
(34 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350....-...360...-.--...370.....----.-.----380.......390.......-400-.......410--.....-..---.420-...-----.....430.......440.......450---.---........460...---....470.-......480.......490.......500.......510.-......520..-....-.530--.......540..-----.....550.....-----------..560.......570..-.....580.......590
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MP
A
T
Q
Q
M
S
R
L
VDSPD
G
V
R
I
A
V
Y
HEGNPDG
P
T
V
V
L
V
HGFPDSH
V
L
W
D
G
V
V
P
L
L
A
E
R
F
R
I
V
R
YDNRGVGRSSVPK
P
I
S
A
Y
T
M
A
H
FA
D
D
F
D
A
V
I
GELSPGE
P
V
H
V
L
AHDWGSV
G
V
W
E
Y
L
RRPGASDRV
A
S
F
TSVSGP
S
Q
D
H
L
V
N
Y
V
Y
GGLRRPWR
P
R
T
F
L
R
A
I
S
Q
T
L
R
L
S
Y
M
A
L
FS
V
P
V
V
A
P
L
L
L
R
V
A
L
S
S
A
A
V
R
R
NMVGDI
P
V
D
Q
IH
H
S
E
T
L
A
R
D
A
AHSVKT
Y
P
A
N
Y
F
R
S
F
SSSRRGRA
I
P
I
V
DV
P
V
Q
L
I
VNSQDPYVRPYGY
D
Q
T
A
R
W
V
P
R
L
W
R
R
DIKAGHFSPMS
H
P
Q
V
M
A
A
A
V
H
D
F
A
D
LADGK
Q
P
S
R
A
L
L
R
A
QVGRPRGYFG
D
T
L
V
S
V
TGAGSGI
G
R
E
T
A
L
A
F
A
REG
A
E
I
V
I
SDI-DE
A
T
V
K
D
T
A
-
A
--
E
I
A
ARGGIAY
P
----
Y
-
V
----
L
DVS
D
A
E
A
V
E
A
F
A
E
R
V
S
AEH-GV
P
-
D
I
V
VNNAGI---GQAGR-FL---DT
P
--
A
E
Q
-----
F
D
R
V
L
A
V
N
L
G
G
V
V
N
G
C
R
A
F
G
Q
R
L
V
ER-----G---TGG
H
I
V
N
V
S
S
M
A
A
Y
---
A
P
L
Q
S
L
S
A
-
Y
C
T
S
K
A
A
T
Y
M
F
S
D
C
L
R
A
E
LDAAGV
G
L
T
T
ICPGVIDT
N
I
V
A
-TTGFHAPGT
D
E
-EKID-GRRG--Q
I
D
K
M
F
A
L
RSY
G
-----
P
D
K
V
A
D
A
I
V
S
A
V
K-----------KKKPIRPVAP
E
A
Y
A
L
Y
G
-
I
S
R
V
L
P
Q
A
L
R
STARLRVI
109
Fugue
82.80
26%
-60
- C1 -
3LLS
8
?
A:
[50-475]
-------------
P
Q
P
E
T
L
R
R
Y
R
A
G
E
P
P
L
T
G
S
L
L
I
G
G
---
A
G
R
V
V
E
P
L
R
A
A
L
E
K
D
Y
D
L
V
G
N
D
S
F
G
G
L
V
F
D
A
T
G
I
T
E
P
A
G
L
K
G
L
H
E
F
F
T
P
V
L
R
N
L
G
R
C
G
R
V
V
V
V
G
G
T
----------------------------------------------------------------------------------------------------
P
E
A
A
A
S
T
N
E
R
I
A
Q
R
A
L
E
G
F
T
R
S
L
G
K
E
L
R
R
G
A
------
T
T
A
L
V
Y
L
S
P
D
A
K
P
A
A
T
G
L
E
S
T
M
R
F
L
---------
L
S
A
K
S
A
Y
V
D
G
Q
V
F
S
V
G
A
D
D
S
T
P
P
A
D
W
E
K
P
---------------
L
D
G
K
V
A
I
V
T
G
A
A
R
G
I
G
A
T
I
A
E
V
F
A
R
D
G
A
H
V
V
A
I
D
V
-
E
S
A
--
A
E
N
L
-
A
--
E
T
A
S
K
V
G
-
G
T
A
----
L
-
W
----
L
D
V
T
A
D
D
A
V
D
K
I
S
E
H
L
R
D
H
H
G
G
K
A
-
D
I
L
V
N
N
A
G
I
---
T
R
D
K
L
-
L
A
---
N
M
D
--
D
A
R
-----
W
D
A
V
L
A
V
N
L
----
L
A
P
L
R
L
T
E
G
L
V
G
N
-----
G
SIG
E
G
G
R
V
I
G
L
S
S
I
A
G
I
---
A
G
N
R
G
Q
T
N
-
Y
A
T
T
K
A
G
M
I
G
I
T
Q
A
L
A
P
G
L
A
A
K
G
I
T
I
N
A
V
A
P
G
F
I
E
R
R
----------------------------------
L
N
S
L
L
-----
Q
G
G
Q
P
V
D
V
A
E
A
I
A
-----------
Y
F
A
S
-----
P
A
S
N
A
V
T
G
N
V
I
R
V
C
G
Q
A
M
I
G
A
------
23
PsiBlast_CBE
73.40
33%
-50
- C2 -
4YAG
1
?
B:
[6-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
A
F
I
T
G
G
A
S
G
I
G
F
G
I
A
Q
R
L
L
A
N
G
A
R
L
V
L
A
D
I
-
R
Q
D
H
L
D
E
A
R
-
Q
FF
E
E
R
Q
Q
G
R
N
V
H
T
----
I
-
R
----
L
D
V
S
D
R
A
Q
M
A
E
A
A
R
E
C
E
A
V
M
-
G
G
P
-
D
I
L
I
N
N
A
G
I
---
D
P
S
G
P
-
F
K
---
D
A
T
--
Y
Q
D
-----
W
D
Y
G
L
A
I
N
L
M
G
P
I
N
G
I
M
A
F
T
P
G
M
R
A
R
-----
G
---
R
G
G
H
I
V
N
T
A
S
L
A
G
L
---
T
P
M
P
S
F
M
A
I
Y
A
T
A
K
A
A
V
I
T
L
T
E
T
I
R
D
S
M
A
E
D
N
I
G
V
T
V
L
M
P
G
P
I
K
S
R
I
-------
H
E
S
G
Q
N
R
P
E
R
F
R
-
A
G
S
G
LA
E
T
E
Q
Q
L
A
K
R
V
V
A
DNWME
P
T
E
V
G
D
M
I
V
D
A
I
V
-----------
H
N
K
---------------------------------
1
PsiBlast_PDB
73.38
34%
-63
- C2 -
3R1I
1
?
A:
[37-253]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
G
A
S
T
G
I
G
K
K
V
A
L
A
Y
A
E
A
G
A
Q
V
A
V
A
A
R
-
H
S
D
A
L
Q
V
V
A
-
D
--
E
I
A
G
V
G
G
K
A
L
P
----
I
-
R
----
C
D
V
T
Q
P
D
Q
V
R
G
M
L
D
Q
M
T
G
E
L
-
G
G
I
-
D
I
A
V
C
N
A
G
I
---
V
S
V
Q
A
-
M
L
---
D
M
P
--
L
E
E
-----
F
Q
R
I
Q
D
T
N
V
T
G
V
F
L
T
A
Q
A
A
A
R
A
M
V
D
Q
-----
G
---
L
G
G
T
I
I
T
T
A
S
M
S
G
H
I
I
N
I
P
-
Q
Q
V
S
H
-
Y
C
T
S
K
A
A
V
V
H
L
T
K
A
M
A
V
E
L
A
P
H
Q
I
R
V
N
S
V
S
P
G
Y
I
R
T
E
L
V
E
P
L
A
D
Y
H
A
--
L
W
E
-
P
K
I
P
L
G
R
M
G
--
R
P
E
E
L
T
G
L
Y
L
Y
------------------------------------------------------------------
10
PsiBlast_PDB
73.31
28%
-64
- C2 -
3IOY
-
?
A:
[11-275]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
G
A
N
G
V
G
I
G
L
V
R
Q
L
L
N
Q
G
C
K
V
A
I
A
D
I
-
R
Q
D
S
I
D
K
A
L
-
A
--
T
L
E
A
E
G
--
S
G
P
----
E
-
V
M
G
V
Q
L
D
V
A
S
R
E
G
F
K
M
A
A
D
E
V
E
A
R
F
-
G
P
V
-
S
I
L
C
N
N
A
G
V
---
N
L
F
Q
P
-
I
E
---
E
S
S
--
Y
D
D
-----
W
D
W
L
L
G
V
N
L
H
G
V
V
N
G
V
T
T
F
V
P
R
M
V
E
R
V
K
A
GE
Q
---
K
G
G
H
V
V
N
T
A
S
M
A
A
F
---
L
A
A
G
S
P
G
I
-
Y
N
T
T
K
F
A
V
R
G
L
S
E
S
L
H
Y
S
L
L
K
Y
E
I
G
V
S
V
L
C
P
G
L
V
K
----------------------------------
A
G
V
H
E
F
G
ME---
P
D
V
I
G
A
R
V
I
E
A
M
K
A
NRLHIFSHPD
H
K
E
E
L
R
E
V
F
D
E
I
I
A
E
Y
--------------------
3
PsiBlast_PDB
73.25
33%
-50
- C2 -
4YAI
2
?
A:
[6-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
A
F
I
T
G
G
A
S
G
I
G
F
G
I
A
Q
R
L
L
A
N
G
A
R
L
V
L
A
D
I
-
R
Q
D
H
L
D
E
A
R
-
Q
F
F
E
E
R
Q
Q
G
R
N
V
H
T
----
I
-
R
----
L
D
V
S
D
R
A
Q
M
A
E
A
A
R
E
C
E
A
V
M
-
G
G
P
-
D
I
L
I
N
N
A
G
I
---
D
P
S
G
P
-
F
K
---
D
A
T
--
Y
Q
D
-----
W
D
Y
G
L
A
I
N
L
M
G
P
I
N
G
I
M
A
F
T
P
G
M
R
A
R
-----
G
---
R
G
G
H
I
V
N
T
A
S
L
A
G
L
---
T
P
M
P
S
F
M
A
I
Y
A
T
A
K
A
A
V
I
T
L
T
E
T
I
R
D
S
M
A
E
D
N
I
G
V
T
V
L
M
P
G
P
I
K
S
R
I
-------
H
E
S
G
Q
N
R
P
E
R
F
R
-
A
G
S
G
L
A
E
T
E
Q
Q
L
A
K
R
V
V
A
DNWME
P
T
E
V
G
D
M
I
V
D
A
I
V
-----------
H
N
K
---------------------------------
2
PsiBlast_PDB
72.97
33%
-51
- C2 -
4YAG
1
?
A:
[6-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
A
F
I
T
G
G
A
S
G
I
G
F
G
I
A
Q
R
L
L
A
N
G
A
R
L
V
L
A
D
I
-
R
Q
D
H
L
D
E
A
R
-
Q
F
F
E
E
R
Q
Q
G
R
N
V
H
T
----
I
-
R
----
L
D
V
S
D
R
A
Q
M
A
E
A
A
R
E
C
E
A
V
M
-
G
G
P
-
D
I
L
I
N
N
A
G
I
---
D
P
S
G
P
-
F
K
---
D
A
T
--
Y
Q
D
-----
W
D
Y
G
L
A
I
N
L
M
G
P
I
N
G
I
M
A
F
T
P
G
M
R
A
R
-----
G
---
R
G
G
H
I
V
N
T
A
S
L
A
G
L
---
T
P
M
P
S
F
M
A
I
Y
A
T
A
K
A
A
V
I
T
L
T
E
T
I
R
D
S
M
A
E
D
N
I
G
V
T
V
L
M
P
G
P
I
K
S
R
I
-------
H
E
S
G
Q
N
R
P
E
R
F
R
-
A
G
S
G
L
A
E
T
E
Q
Q
L
A
K
R
V
V
A
DNWME
P
T
E
V
G
D
M
I
V
D
A
I
V
-----------
H
N
K
---------------------------------
22
PsiBlast_CBE
72.71
33%
-51
- C2 -
4YAI
2
?
B:
[6-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
A
F
I
T
G
G
A
S
G
I
G
F
G
I
A
Q
R
L
L
A
N
G
A
R
L
V
L
A
D
I
-
R
Q
D
H
L
D
E
A
R
-
Q
FF
E
E
R
Q
Q
G
R
N
V
H
T
----
I
-
R
----
L
D
V
S
D
R
A
Q
M
A
E
A
A
R
E
C
E
A
V
M
-
G
G
P
-
D
I
L
I
N
N
A
G
I
---
D
P
S
G
P
-
F
K
---
D
A
T
--
Y
Q
D
-----
W
D
Y
G
L
A
I
N
L
M
G
P
I
N
G
I
M
A
F
T
P
G
M
R
A
R
-----
G
---
R
G
G
H
I
V
N
T
A
S
L
A
G
L
---
T
P
M
P
S
F
M
A
I
Y
A
T
A
K
A
A
V
I
T
L
T
E
T
I
R
D
S
M
A
E
D
N
I
G
V
T
V
L
M
P
G
P
I
K
S
R
I
-------
H
E
S
G
Q
N
R
P
E
R
F
R
-
A
G
S
G
LA
E
T
E
Q
Q
L
A
K
R
V
V
A
DNWME
P
T
E
V
G
D
M
I
V
D
A
I
V
-----------
H
N
K
---------------------------------
34
PsiBlast_CBE
71.00
34%
-73
- C2 -
4NBU
2
?
D:
[13-197]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
A
A
G
K
E
A
------
V
E
A
N
P
G
V
V
F
I
----
R
-
V
-----
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
-
G
K
I
-
D
I
L
I
N
N
A
G
I
---
T
R
D
S
M
-
L
S
---
K
M
T
--
V
D
Q
-----
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
M
A
E
Q
-----
G
---
K
-
G
K
I
I
N
T
S
S
V
T
G
T
---
Y
G
N
V
G
Q
T
N
-
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
V
A
-----------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
70.61
35%
-69
- C2 -
2CFC
2
HCDR_XANP2
A:
[7-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
L
D
L
-
S
A
E
T
L
E
E
T
A
R
T
--
H
W
H
A
Y
A
D
K
V
L
R
----
V
-
R
----
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
-
G
A
I
-
D
V
L
V
N
N
A
G
I
TGN
S
E
A
G
V
-
L
H
---
T
T
P
--
V
E
Q
-----
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
-----
G
----
A
G
V
I
V
N
I
A
S
V
A
S
L
---
V
A
F
P
G
R
S
A
-
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
69.97
34%
-69
- C2 -
4NBU
2
?
B:
[13-197]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
A
A
G
K
E
A
------
V
E
A
N
P
G
V
V
F
I
----
R
-
V
-----
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
-
G
K
I
-
D
I
L
I
N
N
A
G
I
---
T
R
D
S
M
-
L
S
---
K
M
T
--
V
D
Q
-----
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
M
A
E
Q
-----
G
---
K
-
G
K
I
I
N
T
S
S
V
T
G
T
---
Y
G
N
V
G
Q
T
N
-
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
V
A
-----------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
69.48
35%
-66
- C2 -
2CFC
2
HCDR_XANP2
D:
[7-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
L
D
L
-
S
A
E
T
L
E
E
T
A
R
T
--
H
W
H
A
Y
A
D
K
V
L
R
----
V
-
R
----
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
-
G
A
I
-
D
V
L
V
N
N
A
G
I
TGN
S
E
A
G
V
-
L
H
---
T
T
P
--
V
E
Q
-----
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
-----
G
----
A
G
V
I
V
N
I
A
S
V
A
S
L
---
V
A
F
P
G
R
S
A
-
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
69.47
35%
-67
- C2 -
2CFC
2
HCDR_XANP2
B:
[7-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
L
D
L
-
S
A
E
T
L
E
E
T
A
R
T
--
H
W
H
A
Y
A
D
K
V
L
R
----
V
-
R
----
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
-
G
A
I
-
D
V
L
V
N
N
A
G
I
TGN
S
E
A
G
V
-
L
H
---
T
T
P
--
V
E
Q
-----
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
-----
G
----
A
G
V
I
V
N
I
A
S
V
A
S
L
---
V
A
F
P
G
R
S
A
-
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
69.33
34%
-71
- C2 -
4NBU
1
?
C:
[13-197]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
A
A
G
K
E
A
------
V
E
A
N
P
G
V
V
F
I
----
R
-
V
-----
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
-
G
K
I
-
D
I
L
I
N
N
A
G
I
---
T
R
D
S
M
-
L
S
---
K
M
T
--
V
D
Q
-----
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
M
A
E
Q
-----
G
---
K
-
G
K
I
I
N
T
S
S
V
T
G
T
---
Y
G
N
V
G
Q
T
N
-
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
V
A
-----------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
68.69
35%
-66
- C2 -
2CFC
2
HCDR_XANP2
C:
[7-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
L
D
L
-
S
A
E
T
L
E
E
T
A
R
T
--
H
W
H
A
Y
A
D
K
V
L
R
----
V
-
R
----
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
-
G
A
I
-
D
V
L
V
N
N
A
G
I
TGN
S
E
A
G
V
-
L
H
---
T
T
P
--
V
E
Q
-----
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
-----
G
----
A
G
V
I
V
N
I
A
S
V
A
S
L
---
V
A
F
P
G
R
S
A
-
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
68.31
32%
-65
- C2 -
4URF
8
?
A:
[10-230]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
S
D
I
-
S
D
E
W
G
R
E
T
L
-
A
--
L
I
E
G
K
G
G
K
A
V
F
----
Q
-
H
----
A
D
T
A
H
P
E
D
H
D
E
L
I
A
A
A
K
R
A
F
-
G
R
L
-
D
I
A
C
N
N
A
G
I
-----
S
G
E
-
F
T
PTA
E
T
T
--
D
A
Q
-----
W
Q
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
R
A
Q
I
R
A
M
L
E
T
-----
G
----
G
G
A
I
V
N
I
S
S
I
A
G
Q
---
I
G
I
E
G
I
T
P
-
Y
T
A
A
K
H
G
V
V
G
L
T
K
T
V
A
W
E
Y
G
S
K
G
I
R
I
N
S
V
G
P
A
F
I
N
T
T
L
V
Q
-----
N
V
P
-------
L
E
-
T
R
R
---
Q
L
E
Q
M
H
A
L
R
R
L
G
-----
E
T
E
E
V
A
N
L
V
A
W
L
S
-----------
S
D
K
---------------------------------
9
PsiBlast_PDB
68.30
33%
-63
- C2 -
3TJR
1
?
A:
[36-244]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
G
A
S
G
I
G
L
A
T
A
T
E
F
A
R
R
G
A
R
L
V
L
S
D
V
-
D
Q
P
A
L
E
Q
A
V
-
N
--
G
L
R
G
Q
G
F
D
A
H
G
----
V
-
V
----
C
D
V
R
H
L
D
E
M
V
R
L
A
D
E
A
F
R
L
L
-
G
G
V
-
D
V
V
F
S
N
A
G
I
---
V
V
A
G
P
-
L
A
---
Q
M
N
--
H
D
D
-----
W
R
W
V
I
D
I
D
L
W
G
S
I
H
A
V
E
A
F
L
P
R
L
L
E
Q
-----
G
---
T
G
G
H
I
A
F
T
A
S
F
A
G
L
---
V
P
N
A
G
L
G
T
-
Y
G
V
A
K
Y
G
V
V
G
L
A
E
T
L
A
R
E
V
K
P
N
G
I
G
V
S
V
L
C
P
M
V
V
E
T
K
L
V
S
-
N
S
--------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
68.18
34%
-68
- C2 -
3ENN
-
?
A:
[11-195]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
T
G
G
L
G
E
A
I
A
R
A
L
H
A
Q
G
A
I
V
G
L
H
G
T
-
R
E
E
K
L
K
E
L
A
-
A
--
E
L
G
E
R
---
I
F
V
----
F
-
P
----
A
N
L
S
D
R
E
A
V
K
A
L
G
Q
K
A
E
E
E
M
-
G
G
V
-
D
I
L
V
N
N
A
G
I
---
T
R
D
G
L
-
F
V
---
R
M
S
--
D
E
D
-----
W
D
A
V
L
T
V
N
L
T
S
V
F
N
L
T
R
E
L
T
H
P
M
M
R
R
---------
R
N
G
R
I
I
N
I
T
S
I
V
G
V
---
T
G
N
P
G
Q
A
N
-
Y
C
A
S
K
A
G
L
I
G
F
S
K
S
L
A
Q
E
I
A
S
R
N
V
T
V
N
C
I
A
P
G
F
I
E
S
---------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
68.04
34%
-72
- C2 -
3EMK
-
?
A:
[11-192]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
T
G
G
L
G
E
A
I
A
R
A
L
H
A
Q
G
A
I
V
G
L
H
G
T
-
R
E
E
K
L
K
E
L
A
-
A
--
E
L
G
E
R
---
I
F
V
----
F
-
P
----
A
N
L
S
D
R
E
A
V
K
A
L
G
Q
K
A
E
E
E
M
-
G
G
V
-
D
I
L
V
N
N
A
G
I
---
T
R
D
G
L
-
F
V
---
R
M
S
--
D
E
D
-----
W
D
A
V
L
T
V
N
L
T
S
V
F
N
L
T
R
E
L
T
H
P
M
M
R
R
---------
R
N
G
R
I
I
N
I
T
S
I
V
G
V
---
T
G
N
P
G
Q
A
N
-
Y
C
A
S
K
A
G
L
I
G
F
S
K
S
L
A
Q
E
I
A
S
R
N
V
T
V
N
C
I
A
P
G
F
I
E
S
---------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
67.89
37%
-78
- C2 -
3UF0
1
?
B:
[36-213]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
G
S
G
I
G
R
A
I
A
H
G
Y
A
R
A
G
A
H
V
L
A
W
G
R
-
T
D
G
-
V
K
E
V
A
-
D
--
E
I
A
D
G
G
G
S
A
E
A
----
V
-
V
----
A
D
L
A
D
L
E
G
A
A
N
V
A
E
E
L
A
A
T
R
-
R
V
--
D
V
L
V
N
N
A
G
I
---------
I
A
---
R
A
P
--
A
E
E
VSLGR
W
R
E
V
L
T
V
N
L
D
A
A
W
V
L
S
R
S
F
G
T
A
M
L
A
H
-----
G
---
S
G
-
R
I
V
T
I
A
S
M
L
S
F
---
Q
G
G
R
N
V
A
A
-
Y
A
A
S
K
H
A
V
V
G
L
T
R
A
L
A
S
E
W
A
G
R
G
V
G
V
N
A
L
A
P
G
Y
V
V
T
---------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
67.84
34%
-70
- C2 -
4NBU
1
?
A:
[13-197]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
A
A
G
K
E
A
------
V
E
A
N
P
G
V
V
F
I
----
R
-
V
-----
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
-
G
K
I
-
D
I
L
I
N
N
A
G
I
---
T
R
D
S
M
-
L
S
---
K
M
T
--
V
D
Q
-----
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
M
A
E
Q
-----
G
---
K
-
G
K
I
I
N
T
S
S
V
T
G
T
---
Y
G
N
V
G
Q
T
N
-
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
V
A
-----------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
67.78
32%
-63
- C2 -
4URF
5
?
B:
[10-230]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
S
D
I
-
S
D
E
W
G
R
E
T
L
-
A
--
L
I
E
G
K
G
G
K
A
V
F
----
Q
-
H
----
A
D
T
A
H
P
E
D
H
D
E
L
I
A
A
A
K
R
A
F
-
G
R
L
-
D
I
A
C
N
N
A
G
I
-----
S
G
E
-
F
T
PTA
E
T
T
--
D
A
Q
-----
W
Q
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
R
A
Q
I
R
A
M
L
E
T
-----
G
----
G
G
A
I
V
N
I
S
S
I
A
G
Q
---
I
G
I
E
G
I
T
P
-
Y
T
A
A
K
H
G
V
V
G
L
T
K
T
V
A
W
E
Y
G
S
K
G
I
R
I
N
S
V
G
P
A
F
I
N
T
T
L
V
Q
-----
N
V
P
-------
L
E
-
T
R
R
---
Q
L
E
Q
M
H
A
L
R
R
L
G
-----
E
T
E
E
V
A
N
L
V
A
W
L
S
-----------
S
D
K
---------------------------------
26
PsiBlast_CBE
67.65
32%
-63
- C2 -
4URE
5
?
B:
[10-230]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
S
D
I
-
S
D
E
W
G
R
E
T
L
-
A
--
L
I
E
G
K
G
G
K
A
V
F
----
Q
-
H
----
A
D
T
A
H
P
E
D
H
D
E
L
I
A
A
A
K
R
A
F
-
G
R
L
-
D
I
A
C
N
N
A
G
I
-----
S
G
E
-
F
T
PTA
E
T
T
--
D
A
Q
-----
W
Q
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
R
A
Q
I
R
A
M
L
E
T
-----
G
----
G
G
A
I
V
N
I
S
S
I
A
G
Q
---
I
G
I
E
G
I
T
P
-
Y
T
A
A
K
H
G
V
V
G
L
T
K
T
V
A
W
E
Y
G
S
K
G
I
R
I
N
S
V
G
P
A
F
I
N
T
T
L
V
Q
-----
N
V
P
-------
L
E
-
T
R
R
---
Q
L
E
Q
M
H
A
L
R
R
L
G
-----
E
T
E
E
V
A
N
L
V
A
W
L
S
-----------
S
D
K
---------------------------------
79
PsiBlast_CBE
66.94
33%
-66
- C2 -
2PD6
1
DHB8_HUMAN
B:
[9-200]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
L
V
T
G
A
G
S
G
I
G
R
A
V
S
V
R
L
A
G
E
G
A
T
V
A
A
C
D
L
-
D
R
A
A
A
Q
E
T
V
-
R
--
L
L
G
--------N
H
A
A
F
-
Q
----
A
D
V
S
E
A
R
A
A
R
C
L
L
E
Q
V
Q
A
C
F
-
S
R
P
P
S
V
V
V
S
C
A
G
I
---
T
Q
D
E
F
-
L
L
---
H
M
S
--
E
D
D
-----
W
D
K
V
I
A
V
N
L
K
G
T
F
L
V
T
Q
A
A
A
Q
A
L
V
S
N
-----
G
---
C
R
G
S
I
I
N
I
S
S
I
V
G
K
---
V
G
N
V
G
Q
T
N
-
Y
A
A
S
K
A
G
V
I
G
L
T
Q
T
A
A
R
E
L
G
R
H
G
I
R
C
N
S
V
L
P
G
F
I
A
T
---------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
66.77
36%
-62
- C2 -
3WYE
1
BUDC_CORGT (first)
B:
[7-204]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
A
T
A
K
A
V
A
-
S
--
E
I
N
Q
A
G
G
H
A
V
A
----
V
-
K
----
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
-
G
G
F
-
D
V
I
V
N
N
A
G
I
---
A
Q
I
K
P
-
L
L
---
E
V
T
--
E
E
D
-----
L
K
Q
I
Y
S
V
N
V
F
S
V
F
F
G
I
Q
A
A
V
E
A
F
K
K
E
-----
G
---
H
G
G
K
I
I
N
A
A
S
I
A
A
I
---
Q
G
F
P
I
L
S
A
-
Y
S
T
T
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
I
V
G
T
G
M
-------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
66.19
36%
-63
- C2 -
3WYE
1
BUDC_CORGT (first)
A:
[7-189]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
A
T
A
K
A
V
A
-
S
--
E
I
N
Q
A
G
G
H
A
V
A
----
V
-
K
----
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
-
G
G
F
-
D
V
I
V
N
N
A
G
I
---
A
Q
I
K
P
-
L
L
---
E
V
T
--
E
E
D
-----
L
K
Q
I
Y
S
V
N
V
F
S
V
F
F
G
I
Q
A
A
V
E
A
F
K
K
E
-----
G
---
H
G
G
K
I
I
N
A
A
S
I
A
A
I
---
Q
G
F
P
I
L
S
A
-
Y
S
T
T
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
I
V
G
T
G
M
-------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
65.87
33%
-64
- C2 -
2PD6
1
DHB8_HUMAN
D:
[9-200]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
L
V
T
G
A
G
S
G
I
G
R
A
V
S
V
R
L
A
G
E
G
A
T
V
A
A
C
D
L
-
D
R
A
A
A
Q
E
T
V
-
R
--
L
L
---------N
H
A
A
F
-
Q
----
A
D
V
S
E
A
R
A
A
R
C
L
L
E
Q
V
Q
A
C
F
-
S
R
P
P
S
V
V
V
S
C
A
G
I
---
T
Q
D
E
F
-
L
L
---
H
M
S
--
E
D
D
-----
W
D
K
V
I
A
V
N
L
K
G
T
F
L
V
T
Q
A
A
A
Q
A
L
V
S
N
-----
G
---
C
R
G
S
I
I
N
I
S
S
I
V
G
K
---
V
G
N
V
G
Q
T
N
-
Y
A
A
S
K
A
G
V
I
G
L
T
Q
T
A
A
R
E
L
G
R
H
G
I
R
C
N
S
V
L
P
G
F
I
A
T
---------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
65.02
33%
-68
- C2 -
5HA5
8
?
A:
[6-204]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
L
V
L
V
T
G
A
G
R
G
L
G
A
A
I
S
S
G
A
A
E
Q
G
A
R
V
I
L
V
D
I
-
D
G
T
A
A
K
A
Q
A
-
D
--
A
L
T
A
K
G
F
V
A
E
G
----
H
-
A
----
L
D
V
T
D
R
D
A
V
A
A
L
A
D
D
I
L
S
R
F
-
G
G
L
-
D
V
L
V
N
N
A
G
V
-----
A
G
R
A
A
F
---
D
Q
P
E
A
V
E
V
-----
W
D
R
V
I
G
V
N
L
E
G
A
F
N
V
S
H
A
L
V
P
A
L
--
K
-----
A
---
A
K
G
N
V
V
H
L
C
S
V
A
G
F
---
V
S
G
G
S
T
A
G
-
Y
V
V
S
K
G
A
I
R
S
L
T
Q
V
M
A
R
D
L
A
P
H
G
I
R
V
N
A
V
A
P
G
I
M
M
S
E
M
A
V
-
A
Q
L
N
R
P
G
G
T
D
------------------------------------------------------------------------------------------
80
PsiBlast_CBE
64.99
33%
-64
- C2 -
2PD6
1
DHB8_HUMAN
A:
[9-210]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
L
V
T
G
A
G
S
G
I
G
R
A
V
S
V
R
L
A
G
E
G
A
T
V
A
A
C
D
L
-
D
R
A
A
A
Q
E
T
V
-
R
--
L
L
---------N
H
A
A
F
-
Q
----
A
D
V
S
E
A
R
A
A
R
C
L
L
E
Q
V
Q
A
C
F
-
S
R
P
P
S
V
V
V
S
C
A
G
I
---
T
Q
D
E
F
-
L
L
---
H
M
S
--
E
D
D
-----
W
D
K
V
I
A
V
N
L
K
G
T
F
L
V
T
Q
A
A
A
Q
A
L
V
S
N
-----
G
---
C
R
G
S
I
I
N
I
S
S
I
V
G
K
---
V
G
N
V
G
Q
T
N
-
Y
A
A
S
K
A
G
V
I
G
L
T
Q
T
A
A
R
E
L
G
R
H
G
I
R
C
N
S
V
L
P
G
F
I
A
T
---------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
64.44
34%
-72
- C2 -
2ZTV
2
?
B:
[9-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
S
T
S
G
I
G
L
G
I
A
T
A
L
A
A
Q
G
A
D
I
V
L
N
G
F
G
D
A
A
E
I
E
K
V
R
-
A
--
G
L
A
A
Q
H
G
V
K
V
L
----
Y
D
G
----
A
D
L
S
K
G
E
A
V
R
G
L
V
D
N
A
V
R
Q
M
-
G
R
I
-
D
I
L
V
N
N
A
G
I
---
Q
H
T
A
L
-
I
E
---
D
F
P
--
T
E
K
-----
W
D
A
I
L
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
H
M
K
K
Q
-----
G
---
F
-
G
R
I
I
N
I
A
S
A
H
G
L
---
V
A
S
A
N
K
S
A
-
Y
V
A
A
K
H
G
V
V
G
F
T
K
V
T
A
L
E
T
A
G
Q
G
I
T
A
N
A
I
C
P
G
W
V
R
T
P
L
V
------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
64.37
33%
-64
- C2 -
2PD6
1
DHB8_HUMAN
C:
[9-200]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
L
V
T
G
A
G
S
G
I
G
R
A
V
S
V
R
L
A
G
E
G
A
T
V
A
A
C
D
L
-
D
R
A
A
A
Q
E
T
V
-
R
--
L
L
---------N
H
A
A
F
-
Q
----
A
D
V
S
E
A
R
A
A
R
C
L
L
E
Q
V
Q
A
C
F
-
S
R
P
P
S
V
V
V
S
C
A
G
I
---
T
Q
D
E
F
-
L
L
---
H
M
S
--
E
D
D
-----
W
D
K
V
I
A
V
N
L
K
G
T
F
L
V
T
Q
A
A
A
Q
A
L
V
S
N
-----
G
---
C
R
G
S
I
I
N
I
S
S
I
V
G
K
---
V
G
N
V
G
Q
T
N
-
Y
A
A
S
K
A
G
V
I
G
L
T
Q
T
A
A
R
E
L
G
R
H
G
I
R
C
N
S
V
L
P
G
F
I
A
T
---------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
63.92
33%
-67
- C2 -
3O03
3
?
A:
[39-230]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
A
S
Y
G
I
G
F
A
I
A
S
A
Y
A
K
A
G
A
T
I
V
F
N
D
I
-
N
Q
E
L
V
D
R
G
M
-
A
--
A
Y
K
A
A
G
I
N
A
H
G
----
Y
-
V
----
C
D
V
T
D
E
D
G
I
Q
A
M
V
A
Q
I
E
S
E
V
-
G
I
I
-
D
I
L
V
N
N
A
G
I
---
I
R
R
V
P
-
M
I
---
E
M
T
--
A
A
Q
-----
F
R
Q
V
I
D
I
D
L
N
A
P
F
I
V
S
K
A
V
I
P
S
M
I
K
K
-----
G
---
H
-
G
K
I
I
N
I
C
S
M
M
S
E
---
L
G
R
E
T
V
S
A
-
Y
A
A
A
K
G
G
L
K
M
L
T
K
N
I
A
S
E
Y
G
E
A
N
I
Q
C
N
G
I
G
P
G
Y
I
A
T
---------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
62.18
34%
-65
- C2 -
2ZTU
2
?
C:
[9-204]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
S
T
S
G
I
G
L
G
I
A
T
A
L
A
A
Q
G
A
D
I
V
L
N
G
F
G
D
A
A
E
I
E
K
V
R
-
A
--
G
L
A
A
Q
H
G
V
K
V
L
----
Y
D
G
----
A
D
L
S
K
G
E
A
V
R
G
L
V
D
N
A
V
R
Q
M
-
G
R
I
-
D
I
L
V
N
N
A
G
I
---
Q
H
T
A
L
-
I
E
---
D
F
P
--
T
E
K
-----
W
D
A
I
L
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
H
M
K
K
Q
-----
G
---
F
-
G
R
I
I
N
I
A
S
A
H
G
L
---
V
A
S
A
N
K
S
A
-
Y
V
A
A
K
H
G
V
V
G
F
T
K
V
T
A
L
E
T
A
G
Q
G
I
T
A
N
A
I
C
P
G
-------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
61.94
34%
-67
- C2 -
2ZTU
1
?
D:
[9-205]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
S
T
S
G
I
G
L
G
I
A
T
A
L
A
A
Q
G
A
D
I
V
L
N
G
F
G
D
A
A
E
I
E
K
V
R
-
A
--
G
L
A
A
Q
H
G
V
K
V
L
----
Y
D
G
----
A
D
L
S
K
G
E
A
V
R
G
L
V
D
N
A
V
R
Q
M
-
G
R
I
-
D
I
L
V
N
N
A
G
I
---
Q
H
T
A
L
-
I
E
---
D
F
P
--
T
E
K
-----
W
D
A
I
L
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
H
M
K
K
Q
-----
G
---
F
-
G
R
I
I
N
I
A
S
A
H
G
L
---
V
A
S
A
N
K
S
A
-
Y
V
A
A
K
H
G
V
V
G
F
T
K
V
T
A
L
E
T
A
G
Q
G
I
T
A
N
A
I
C
P
G
-------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
61.93
34%
-64
- C2 -
2ZTU
1
?
A:
[9-211]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
S
T
S
G
I
G
L
G
I
A
T
A
L
A
A
Q
G
A
D
I
V
L
N
G
F
G
D
A
A
E
I
E
K
V
R
-
A
--
G
L
A
A
Q
H
G
V
K
V
L
----
Y
D
G
----
A
D
L
S
K
G
E
A
V
R
G
L
V
D
N
A
V
R
Q
M
-
G
R
I
-
D
I
L
V
N
N
A
G
I
---
Q
H
T
A
L
-
I
E
---
D
F
P
--
T
E
K
-----
W
D
A
I
L
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
H
M
K
K
Q
-----
G
---
F
-
G
R
I
I
N
I
A
S
A
H
G
L
---
V
A
S
A
N
K
S
A
-
Y
V
A
A
K
H
G
V
V
G
F
T
K
V
T
A
L
E
T
A
G
Q
G
I
T
A
N
A
I
C
P
G
-------------------------------------------------------------------------------------------------------------