@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2302: (2016-05-09 )
MHAKVGDYLVVKGTTTERHDQHAEIIEVRSADGSPPYVVRWLVNGHETTVYPGSDAVVVTATEHAEAEKRAAARAGHAAT
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10...-----..--...--------20......--..30-------------....-....40.......-.50.---------.......60........70........80----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHAKVG
D
Y
L
V
V
KGT-----TT--ERH--------DQH
A
E
I
I
E
--
V
RSA-------------DGSP-
P
Y
V
V
R
W
L
VNGH
E
T
-
T
V
YP---------GS
D
A
V
V
V
T
AT
E
H
A
E
A
E
K
R
A
A
ARAGHAAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
90.57
100%
-53
- C3 -
2A7Y
-
Y2302_MYCTU
A:
[1-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
A
K
V
G
D
Y
L
V
V
K
G
T
-----
T
T
--
E
R
H
--------
D
Q
H
A
E
I
I
E
--
V
R
S
A
-------------
D
G
S
P
-
P
Y
V
V
R
W
L
V
N
G
H
E
T
-
T
V
Y
P
---------
G
S
D
A
V
V
V
T
A
T
E
H
A
E
A
E
K
R
A
A
A
R
A
G
H
A
A
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
90.57
100%
-53
- C3 -
2A7Y
-
Y2302_MYCTU
A:
[1-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
A
K
V
G
D
Y
L
V
V
K
G
T
-----
T
T
--
E
R
H
--------
D
Q
H
A
E
I
I
E
--
V
R
S
A
-------------
D
G
S
P
-
P
Y
V
V
R
W
L
V
N
G
H
E
T
-
T
V
Y
P
---------
G
S
D
A
V
V
V
T
A
T
E
H
A
E
A
E
K
R
A
A
A
R
A
G
H
A
A
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
90.57
100%
-53
- C3 -
2A7Y
-
Y2302_MYCTU
A:
[1-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
A
K
V
G
D
Y
L
V
V
K
G
T
-----
T
T
--
E
R
H
--------
D
Q
H
A
E
I
I
E
--
V
R
S
A
-------------
D
G
S
P
-
P
Y
V
V
R
W
L
V
N
G
H
E
T
-
T
V
Y
P
---------
G
S
D
A
V
V
V
T
A
T
E
H
A
E
A
E
K
R
A
A
A
R
A
G
H
A
A
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
57.80
18%
-79
- C3 -
4P5N
9
?
A:
[12-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
N
V
G
D
T
V
Y
T
P
--------
Y
--
R
G
G
--------
K
H
E
G
Q
V
A
D
--
I
V
T
T
K
E
E
A
A
E
K
G-----
V
K
N
P
-
P
K
V
L
F
T
D
Q
N
N
K
D
V
-
A
H
N
P
---------
G
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
57.11
28%
-82
- C1 -
4V36
1
?
A:
[55-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
V
G
Q
R
L
V
V
L
G
D
-----
P
S
--
G
R
E
--------
D
S
F
P
L
V
I
K
E
F
L
H
A
A
-------------
D
Q
K
G
-
Y
L
V
I
F
Y
Q
I
E
R
E
D
M
-
A
L
Y
H
DFG
Y
R
F
F
K
L
G
E
E
A
I
V
D
L
D
T
F
T
I
S
G
K
K
R
A
G
L
R
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
49.95
21%
-69
- C2 -
3BK2
7
RNJ_THET2
A:
[14-562]
Q
D
H
V
E
I
I
P
LGGMGEIGK
N
I
T
V
F
R
F
RD
E
I
F
V
L
D
G
G
L
A
F
P
E
EGMPGVD
L
L
I
P
R
V
D
Y
L
I
E
H
R
HKIK
A
W
V
L
THGHEDHIGG
L
P
F
L
L
P
M
I
FGKESPV
P
I
Y
G
A
R
L
T
L
G
L
L
R
G
K
L
E
E
F
GLRPGA
F
N
L
K
E
I
S
PD
D
R
I
Q
V
G
RY
F
T
L
D
L
F
R
M
T
H
SIPD
N
S
G
V
VIRTPI
G
T
I
V
H
TGDFKLDPTPIDGKVSHL
A
K
V
A
Q
A
G
A
E
GVL
L
L
I
A
D
ATNAERPGYTPS
E
M
E
I
A
K
E
L
D
R
V
I
G
R
AP
G
R
V
F
V
T
T
F
ASH
I
H
R
I
Q
S
V
I
W
A
A
E
K
Y
G
R
K
V
A
M
E
G
R
S
M
L
K
F
S
R
I
A
L
E
L
G
Y
L
K
V
K
D
R
L
Y
T
LE
E
V
--
K
D
L
--------
P
D
H
Q
V
L
I
L
--
A
T
G
S
-------------
Q
G
Q
P
M
S
V
L
H
R
L
A
F
E
G
H
A
K
M
A
I
K
P
---------
G
-
D
T
V
I
L
S
S
S
P
I
P
G
N
E
E
A
V
N
R
V
I
N
R
L
Y
A
L
GAY
V
L
Y
P
PTYKVHASGHAS
Q
E
E
L
K
L
I
L
N
L
T
TPR
F
F
L
P
W
HGE
V
R
H
Q
M
N
F
K
W
L
A
E
S
MSRPPEKTLIGENG
A
V
Y
R
L
T
RE
T
F
E
K
VGE
V
P
H
G
V
L
Y
V
D
GLGVGDIT
E
E
I
L
A
D
R
R
H
M
A
E
E
G
L
V
V
I
T
A
L
A
G
ED
P
V
V
E
V
V
S
R
GFV
K
A
G
E
R
L
L
G
E
V
R
R
M
A
L
E
A
L
K
N
G
V
R
E
KKP
L
E
R
I
R
D
D
I
Y
Y
P
V
K
K
F
L
K
K
A
TGRD
P
M
I
L
P
V
V
I
E
G
11
HHSearch
49.53
18%
-57
- C3 -
4HCZ
1
PHF1_HUMAN
A:
[4-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
E
G
Q
D
V
L
A
R
W
T
---------
D
G
L
--------
L
Y
L
G
T
I
K
K
--
V
D
S
A
-------------
R
E
---
V
C
L
V
Q
F
E
D
D
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
48.62
19%
-64
- C3 -
4PLI
-
MRG2_ARATH
A:
[11-47]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
E
G
E
R
V
L
A
K
H
S
----------
D
C
--------
F
Y
E
A
K
V
L
K
--
V
E
F
K
-------------
D
N
E
W
-
K
Y
F
V
H
Y
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
48.14
22%
-61
* C3 *
3S6W
2
A:
[2-46]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
K
P
G
D
E
C
F
A
L
Y
W
------
E
--
D
N
K
--------
F
Y
R
A
E
V
E
A
--
L
--
S
---------------
G
M
-
T
A
V
V
K
F
I
D
Y
G
N
Y
E
-
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
47.35
17%
-76
- C3 -
2XK0
-
A:
[22-62]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
L
Q
E
D
V
F
I
K
C
N
---------
D
G
R
--------
F
Y
L
G
T
I
I
D
--
Q
----------------
T
-
S
D
-
Q
Y
L
I
R
F
D
D
-
Q
S
E
Q
-
W
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
45.53
21%
-86
- C3 -
2E5Q
-
PHF19_HUMAN
A:
[8-46]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
G
Q
Y
V
L
C
R
W
T
---------
D
G
L
--------
Y
Y
L
G
K
I
K
R
--
V
S
S
S
-------------
K
--
Q
-
S
C
L
V
T
F
E
D
N
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
45.46
18%
-79
- C3 -
2M0O
1
PHF1_HUMAN
A:
[27-65]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
E
G
Q
D
V
L
A
R
W
T
---------
D
G
L
--------
L
Y
L
G
T
I
K
K
--
V
D
S
A
-------------
R
E
---
V
C
L
V
Q
F
E
D
D
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
43.21
24%
-35
- C3 -
4QQG
-
KAT5_HUMAN
A:
[7-49]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
E
G
C
R
L
P
V
L
R
R
-----
N
Q
DN
E
D
E
--------
W
P
L
A
E
I
L
S
--
V
K
D
I
-------------
S
G
R
K
-
L
F
Y
V
H
Y
I
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
42.77
15%
-75
- C3 -
3VYG
1
SCNA_THITI
A:
[36-97]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
N
V
G
D
R
V
R
I
K
D
L
-----
P
D
--
L
F
Y
TRTMTYTR
G
A
T
G
T
I
V
R
--
L
V
Y
E
S
P
A
A
E
D
E
A
F
GNEE
N
V
E
W
-
F
Y
S
I
V
F
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
42.48
16%
-67
- C3 -
2RO0
-
ESA1_YEAST
A:
[21-58]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
I
K
C
Q
C
W
V
Q
K
----------
N
D
E
--------
E
R
L
A
E
I
L
S
--
I
N
T
R
-------------
K
A
P
P
-
K
F
Y
V
H
Y
V
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
42.22
18%
-69
- C3 -
2E5P
-
PHF1_HUMAN
A:
[10-48]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
E
G
Q
D
V
L
A
R
W
T
---------
D
G
L
--------
L
Y
L
G
T
I
K
K
--
V
D
S
A
-------------
R
E
---
V
C
L
V
Q
F
E
D
D
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
40.68
33%
-74
- C4 -
2PET
-
BCAM_HUMAN
A:
[125-163]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
T
-----
L
S
--
V
M
E
--------
D
S
A
Q
E
I
A
T
--
C
N
S
R
-------------
N
G
N
P
-
A
P
K
I
T
W
Y
R
N
G
Q
R
L
-
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
38.99
17%
-53
- C3 -
2LDM
-
PHF20_HUMAN
A:
[87-342]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
I
N
E
Q
V
L
A
S
W
S
---------
D
S
R
--------
F
Y
P
A
K
V
T
A
--
V
N
K
----------------
D
G
-
T
Y
T
V
K
F
Y
D
-
G
V
V
Q
-
T
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
38.87
16%
-84
- C3 -
2RNZ
-
ESA1_YEAST
A:
[21-58]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
I
K
C
Q
C
W
V
Q
K
----------
N
D
E
--------
E
R
L
A
E
I
L
S
--
I
N
T
R
-------------
K
A
P
P
-
K
F
Y
V
H
Y
V
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
38.63
33%
-72
- C4 -
2PF6
-
BCAM_HUMAN
A:
[125-163]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
T
-----
L
S
--
V
M
E
--------
D
S
A
Q
E
I
A
T
--
C
N
S
R
-------------
N
G
N
P
-
A
P
K
I
T
W
Y
R
N
G
Q
R
L
-
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------