@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2335: (2016-05-09 )
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI
Atome Classification :
(27 SA)
------------------------------------------------------------------------.........10........20........30........40........50........60........70........80........90........100.......110--------.--------......120.......130.......140.......150.......160.......170........180.......190.......200.......210.......220.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------MLTAMRG
D
I
R
A
ARERDPAAP
T
A
L
E
V
I
F
CYPG
V
H
A
V
W
G
H
R
L
A
H
W
L
W
Q
R
G
A
R
L
L
A
R
A
A
A
E
F
T
R
I
L
TGVDIHPG
A
V
I
G
A
R
V
F
I
DHAT
G
V
V
IGETAEVGD
D
V
T
I
Y
H
G
V
T
LGGSGMV--------G--------GKRHPTVG
D
R
V
I
IGAG
A
K
V
L
G
P
I
K
IGEDSRIGA
N
A
V
V
V
KPVPP
S
A
V
V
V
GV
P
G
Q
VIGQS-QPSPGGPFDWR
L
P
D
L
V
G
A
S
L
D
S
L
L
T
R
V
A
R
L
E
ALGGGPQAAGVIRPPEAGIWHGEDFSI
110
Fugue
93.12
43%
-123
- C2 -
1SSQ
2
CYSE_HAEIN
A:
[1-241]
MN
L
D
V
W
Q
H
I
R
Q
E
A
K
E
L
A
E
N
E
PML
A
S
F
F
H
S
T
ILKHQN
L
G
G
A
L
S
Y
L
L
A
N
K
L
ANPIMP
A
I
S
L
R
E
I
I
E
E
A
Y
Q
S
NP
S
I
I
D
C
A
A
C
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
--------
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
S
-------------------------------------------------------------
40
PsiBlast_CBE
82.54
47%
-129
- C2 -
4H7O
5
?
C:
[84-248]
-------------------------------------------------------------------------------
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
--------
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
G
V
P
A
R
I
V
G
R
P
-
Q
---------------------------------------------------------
45
PsiBlast_CBE
82.29
44%
-132
- C2 -
3GVD
12
?
L:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
120
HHSearch
82.23
46%
-122
- C2 -
4H7O
3
?
A:
[79-249]
--------------------------------------------------------------------------
E
A
A
A
C
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
--------
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
G
V
P
A
R
I
V
G
R
P
-
Q
S
--------------------------------------------------------
13
PsiBlast_PDB
82.20
46%
-127
- C2 -
3P47
2
?
A:
[104-268]
---------------------------------------------------------------------------
T
L
K
T
D
L
I
A
A
Y
A
G
D
P
A
A
P
G
L
S
L
I
I
R
C
Y
P
G
F
Q
A
V
I
V
Y
R
I
A
H
V
L
Y
E
C
G
E
R
Y
Y
C
R
E
M
M
E
S
V
H
S
Y
T
S
I
D
I
H
P
G
A
S
I
K
G
H
F
F
I
D
H
G
V
G
V
V
I
G
E
T
A
I
I
G
E
W
C
R
I
Y
Q
S
V
T
L
G
A
M
H
F
Q
EEGGVIKR
G
--------
T
K
R
H
P
T
V
G
D
Y
V
T
I
G
T
G
A
K
V
L
G
N
I
I
V
G
S
H
V
R
I
G
A
N
C
W
I
D
R
D
V
D
S
N
Q
T
V
----------------------------------------------------------------------
28
PsiBlast_CBE
82.11
45%
-127
- C2 -
4HZD
1
?
B:
[91-260]
----------------------------------------------------------------------------
L
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
--------
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
G
V
P
A
R
I
I
G
E
T
G
C
T
--------------------------------------------------------
55
PsiBlast_CBE
81.64
44%
-123
- C2 -
3GVD
5
?
B:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
46
PsiBlast_CBE
81.59
44%
-128
- C2 -
3GVD
12
?
K:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
25
PsiBlast_CBE
81.28
47%
-132
- C2 -
4N6B
1
?
B:
[88-255]
------------------------------------------------------------------------
L
R
S
A
A
V
A
D
L
R
A
A
R
E
R
D
P
A
C
V
S
Y
S
H
C
L
L
N
Y
K
G
F
L
A
C
Q
A
H
R
V
A
H
L
L
W
R
Q
S
R
R
P
L
A
L
A
L
H
S
R
I
A
N
V
F
A
V
D
I
H
P
A
A
R
I
G
K
G
I
L
F
D
H
A
T
G
V
V
V
G
E
T
A
V
I
G
N
N
V
S
I
L
H
H
V
T
L
G
G
T
--------------------
G
D
R
H
P
K
I
G
D
G
V
L
I
G
A
G
A
T
I
L
G
N
I
K
I
G
E
G
A
K
V
G
A
G
S
V
V
L
I
D
V
P
P
R
T
T
A
V
G
N
P
A
R
L
V
--------------------------------------------------------------
118
HHSearch
81.19
45%
-123
- C2 -
4HZD
2
?
A:
[88-260]
-------------------------------------------------------------------------
S
H
V
L
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
--------
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
G
V
P
A
R
I
I
G
E
T
-
G
C
T
-------------------------------------------------------
122
HHSearch
81.09
43%
-120
- C2 -
1SSQ
2
CYSE_HAEIN
A:
[74-241]
-------------------------------------------------------------------------
I
D
C
A
A
C
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
--------
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
S
-------------------------------------------------------------
54
PsiBlast_CBE
81.04
44%
-130
- C2 -
3GVD
6
?
C:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
44
PsiBlast_CBE
80.80
44%
-125
- C2 -
1SSQ
2
CYSE_HAEIN
D:
[80-244]
-------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
--------
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
S
Q
D
-
K
---------------------------------------------------------
51
PsiBlast_CBE
80.77
44%
-124
- C2 -
3GVD
5
?
F:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
12
PsiBlast_PDB
80.75
44%
-128
- C2 -
3GVD
5
?
A:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
121
HHSearch
80.73
44%
-129
- C2 -
3Q1X
2
?
A:
[99-267]
------------------------------------------------------------------------
I
K
R
T
L
K
T
D
L
I
A
A
Y
A
G
D
P
A
A
P
G
L
S
L
I
I
R
C
Y
P
G
F
Q
A
V
I
V
Y
R
I
A
H
V
L
Y
E
C
G
E
R
Y
Y
C
R
E
M
M
E
S
V
H
S
Y
T
S
I
D
I
H
P
G
A
S
I
K
G
H
F
F
I
D
H
G
V
G
V
V
I
G
E
T
A
I
I
G
E
W
C
R
I
Y
Q
S
V
T
L
G
A
M
H
F
Q
--------
E
EGGVIKRG
T
K
R
H
P
T
V
G
D
Y
V
T
I
G
T
G
A
K
V
L
G
N
I
I
V
G
S
H
V
R
I
G
A
N
C
W
I
D
R
D
V
D
S
N
Q
T
V
Y
---------------------------------------------------------------------
41
PsiBlast_CBE
80.66
47%
-123
- C2 -
4H7O
4
?
B:
[84-248]
-------------------------------------------------------------------------------
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
--------
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
G
V
P
A
R
I
V
G
R
P
-
Q
---------------------------------------------------------
53
PsiBlast_CBE
80.64
44%
-126
- C2 -
3GVD
4
?
D:
[80-249]
------------------------------------------------------------------------
M
I
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
--------
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
G
V
P
A
R
I
V
G
K
------------------------------------------------------------
4
PsiBlast_PDB
80.53
45%
-125
- C2 -
4HZD
2
?
A:
[91-260]
----------------------------------------------------------------------------
L
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
--------
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
G
V
P
A
R
I
I
G
E
T
G
C
T
--------------------------------------------------------
27
PsiBlast_CBE
80.49
47%
-130
- C2 -
4N69
2
?
B:
[88-255]
------------------------------------------------------------------------
L
R
S
A
A
V
A
D
L
R
A
A
R
E
R
D
P
A
C
V
S
Y
S
H
C
L
L
N
Y
K
G
F
L
A
C
Q
A
H
R
V
A
H
L
L
W
R
Q
S
R
R
P
L
A
L
A
L
H
S
R
I
A
N
V
F
A
V
D
I
H
P
A
A
R
I
G
K
G
I
L
F
D
H
A
T
G
V
V
V
G
E
T
A
V
I
G
N
N
V
S
I
L
H
H
V
T
L
G
G
T
G
K
V
--------
G
--------
G
D
R
H
P
K
I
G
D
G
V
L
I
G
A
G
A
T
I
L
G
N
I
K
I
G
E
G
A
K
V
G
A
G
S
V
V
L
I
D
V
P
P
R
T
T
A
V
G
N
P
A
R
L
V
--------------------------------------------------------------
14
PsiBlast_PDB
80.38
46%
-127
- C2 -
3Q1X
2
?
A:
[102-266]
---------------------------------------------------------------------------
T
L
K
T
D
L
I
A
A
Y
A
G
D
P
A
A
P
G
L
S
L
I
I
R
C
Y
P
G
F
Q
A
V
I
V
Y
R
I
A
H
V
L
Y
E
C
G
E
R
Y
Y
C
R
E
M
M
E
S
V
H
S
Y
T
S
I
D
I
H
P
G
A
S
I
K
G
H
F
F
I
D
H
G
V
G
V
V
I
G
E
T
A
I
I
G
E
W
C
R
I
Y
Q
S
V
T
L
G
A
M
H
F
Q
EEGGVIKR
G
--------
T
K
R
H
P
T
V
G
D
Y
V
T
I
G
T
G
A
K
V
L
G
N
I
I
V
G
S
H
V
R
I
G
A
N
C
W
I
D
R
D
V
D
S
N
Q
T
V
----------------------------------------------------------------------
6
PsiBlast_PDB
80.25
47%
-123
* C2 *
4H7O
3
?
A:
[84-248]
-------------------------------------------------------------------------------
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
--------
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
G
V
P
A
R
I
V
G
R
P
-
Q
---------------------------------------------------------
43
PsiBlast_CBE
79.82
44%
-134
- C2 -
1SST
2
CYSE_HAEIN
B:
[80-240]
-------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
---------------------
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
--------------------------------------------------------------
42
PsiBlast_CBE
79.48
44%
-133
- C2 -
1SST
2
CYSE_HAEIN
C:
[80-240]
-------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
--------------------
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
--------------------------------------------------------------
8
PsiBlast_PDB
79.46
44%
-121
- C2 -
1SSQ
2
CYSE_HAEIN
A:
[80-241]
-------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
--------
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
S
-------------------------------------------------------------
9
PsiBlast_PDB
79.01
46%
-126
- C2 -
1T3D
1
CYSE_ECOLI
A:
[100-261]
-------------------------------------------------------------------------------
D
I
Q
A
V
R
T
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
N
Q
G
R
R
A
L
A
I
F
L
Q
N
Q
V
S
V
T
F
Q
V
D
I
H
P
A
A
K
I
G
R
G
I
M
L
D
H
A
T
G
I
V
V
G
E
T
A
V
I
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
S
--------
G
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
P
V
P
P
H
T
T
A
A
G
V
P
A
R
I
V
G
-------------------------------------------------------------
7
PsiBlast_PDB
78.46
44%
-137
- C2 -
1SST
2
CYSE_HAEIN
A:
[80-240]
-------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
-----------------------
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
G
V
P
A
R
I
V
--------------------------------------------------------------