@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2376c: (2016-05-10 )
MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAPLPLDPASAPDVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTEARIADHKLKKAAEHGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPVTQNVTFVNQGGWMLSRASAMELLQAAGN
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------.........--10........20........30....-....40......-----..50........60..--......70........80........90........100....-...110---......--.---120.......130-.-...--..---..140--...--.....--.--150.......160......---------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
M
V
K
S
I
A
A
--
G
L
T
A
A
A
A
I
G
A
A
A
A
G
V
T
S
IMAGG
P
V
V
Y
-
Q
MQP
V
V
FGAPLP-----LDPASAPDVP
T
A
A
Q
L
T
--
S
L
L
N
S
LADPNVSFANKGSLVEGGIGGT
E
A
R
I
A
D
H
K
L
K
K
A
AEHG-DL
P
L
S
F
---
S
VTNIQ--P---AAAGS
A
T
A
D
V
S
V--S-GPK--LS---SPV----TQ
N
--
V
T
F
VN--Q--G
G
W
M
L
S
R
A
S
A
M
E
L
L
Q
AAGN---------------------------------------------------------------------------------------------
28
Fugue
68.34
20%
-36
* C4 *
4NZR
1
Y281_MYCGE
M:
[26-416]
NDGSYQSEIDLSGGANFREKFRNFANELSEAITNSPKGLDRPVPKTEISGLIKTGDNFITPSFKAGYYDHVASDGSLLSYYQSTEYFNNRVLMPILQTTNGTLMANNRGYDDVFRQVPSFSGWSNTKATTVSTSNNLTYDKWTYFAAKGSPLYDSYP
N
H
F
F
E
D
V
K
T
--
L
A
I
D
A
K
D
I
S
A
L
---
K
T
T
I
D
S
E
K
P
T
Y
L
-
I
I
R
----
G
L
S
G
N
-----
G
S
Q
L
N
E
L
Q
L
P
E
S
V
K
K
V
--
S
L
Y
G
D
Y
T
G
V
N
V
A
K
Q
I
F
A
N
V
V
E
L
E
F
Y
S
T
S
K
-----------------
A
N
S
F
---
G
F
N
P
L
V
--
L
---
G
S
K
T
N
V
I
Y
D
L
F
A
--
S
-
K
P
---
F
T
---
H
I
D
----
L
T
Q
--
V
T
L
Q
N
--
S
--
D
N
---
S
A
I
D
A
N
K
L
K
Q
A
V
G
D
IYNYRRFERQFQGYFAGGYIDKYLVKNVNTNKDSDDDLVYRSLKELNLHLEEAYREGDNTYYRVNENYYPGASIYENERASRDSEFQNEILKR
7
HHSearch
67.04
21%
-51
- C2 -
2RSX
-
YOEB_BACSU
A:
[58-154]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
G
T
K
A
K
A
V
--
N
Y
L
T
P
I
F
T
K
T
A
I
E
K
--------
G
F
K
D
Y
H
F
T
V
S
K
G
K
L
A
V
P
I
G
D
G
-
D
N
L
L
N
W
KK
S
T
A
K
L
I
S
--
K
---
K
G
-
S
--
T
I
T
Y
E
F
--
T
-
V
P
T
LD
G
S
---
P
S
A
----
K
R
K
--
V
T
F
V
K
--
E
N-
K
K
W
K
V
N
Q
---------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
63.25
27%
13
- C3 -
1UB2
-
KATG_SYNE7
A:
[422-526]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
D
V
P
-
Q
-
E
D
L
I
W
Q
D
P
I
P
AGNRN
Y
D
V
Q
A
V
K
D
R
I
A
A
S
G
L
S
I
S
E
L
V
S
T
A
W
D
S
A
R
T
Y
R
N
S
D
K
--
R
G
G
A
N
G
A
R
I
R
L
A
P
Q
K
D
W
E
G
N
E
P
D
-
R
L
P
K
V
L
---
A
V
L
E
G
I
--
S
---
A
A
T
G
A
T
V
A
D
V
I
V
----------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
62.55
16%
-24
- C3 -
4XU6
5
?
A:
[1-189]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
L
R
I
S
E
A
V
--
V
L
F
L
L
G
A
V
A
A
L
I
G
D
H
S
H
V
V
T
G
T
T
V
Y
H
T
D
A
V
P
F
V
W
S
S
P
F
W
-----
F
P
I
L
V
G
A
A
T
A
S
L
A
E
L
R
--
L
H
L
P
A
P
R
D
G
V
T
--
A
C
Q
A
L
G
G
V
A
A
V
V
G
T
Y
V
T
T
A
L
V
H
A
F
P
V
V
P
V
T
-
A
L
V
A
A
A
---
A
A
I
T
W
C
--
V
LGD
G
P
G
A
A
A
G
V
V
I
A
V
--
I
-
G
P
A
--
V
E
---
I
A
L
----
V
Q
L
GV
F
A
Y
H
P
--
D
--
S
D
G
L
F
G
V
A
P
F
L
A
P
L
Y
F
A
F
G
V
V
A
A
L
L
G
E
L
A
V
A
R
RPQL----------------------------------------------------------------------------
33
Fugue
62.04
16%
-58
- C4 -
2JTD
-
A:
[1-122]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
E
M
K
R
L
L
A
LS
Q
E
H
K
F
P
T
V
P
T
K
S
E
L
A
V
E
I
L
E
K
G
Q
V
R
F
-
W
M
Q
-------------------
A
E
K
L
S
S
N
A
K
V
S
--
Y
I
F
N
E
----------------------
K
E
I
F
E
G
P
K
Y
K
M
H
I
D
R
N
-
T
G
I
I
E
M
---
F
M
E
K
L
Q
--
D
---
E
D
E
G
T
Y
T
F
Q
I
Q
D
--
G
------------
K
A
----
T
G
H
--
S
T
L
V
L
--
I
--
G
D
V
Y
K
K
L
Q
K
E
A
E
F
---------------------------------------------------------------------------------------------------
12
HHSearch
59.01
15%
-89
- C2 -
3B7C
6
?
A:
[68-118]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
F
---
T
I
K
E
I
K
--
M
---
L
S
N
Y
A
A
M
V
V
G
R
W
D
L
K
-
R
L
K
--
D
-----
T
P
----
T
G
V
F
T
L
L
V
E
K
--
I
D-
D
R
W
V
I
T
M
D
--------------------------------------------------------------------------------------------------------
5
HHSearch
51.42
17%
-68
- C2 -
3DUK
4
?
A:
[73-120]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
S
---
R
I
T
N
I
D
--
I
---
V
G
-
T
V
A
H
A
R
V
E
A
--
E
N
W
T
N
--
F
K
-----
F
----
S
D
L
--
F
L
L
L
K
--
L
D-
G
K
W
T
I
V
N
K
V
-------------------------------------------------------------------------------------------------------
8
HHSearch
49.43
13%
-65
- C2 -
3BLZ
-
?
A:
[74-121]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
A
---
A
I
A
R
I
D
--
I
---
V
G
T
-
A
A
S
A
R
I
D
T
--
D
D
I
S
G
--
F
-----
R
F
----
T
D
F
--
F
N
L
L
K
--
V
E-
G
K
W
T
V
V
S
K
I
-------------------------------------------------------------------------------------------------------
32
Fugue
48.83
23%
-11
- C2 -
1QUB
-
APOH_HUMAN
A:
[244-319]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
C
K
V
P
V
K
K
A
T
V
V
Y
Q
G
----
E
R
V
K
I
Q
E
K
F
K
N
G
M
L
H
G
-
D
-
K
V
S
F
---
F
C
K
N
----
K
---
E
K
K
C
S
Y
T
E
D
A
Q
C
--
I
-
D
G
T
--
I
E
---
V
P
K
CFKE
H
T
D
--
A
S
D
V
K
--
P
--
C
---------------------------------------------------------------------------------------------------------------
11
HHSearch
47.64
20%
-32
- C2 -
2RCD
-
?
A:
[72-123]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
R
---
A
L
R
N
T
V
I
T
T
---
Y
G
H
D
M
A
V
A
S
T
E
F
--
T
-
R
T
G
--
S
T
---
K
I
G
----
R
Q
M
--
Q
T
W
V
K
--
M
P-
E
G
W
R
I
V
A
A
H
-------------------------------------------------------------------------------------------------------
3
HHSearch
46.38
16%
-59
- C2 -
3K7C
2
?
A:
[68-112]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
I
---
Q
I
E
E
K
T
--
I
---
N
K
-
D
S
A
K
I
R
V
L
V
--
L
-
F
N
N
--
D
N
----
N
Q
----
S
S
N
--
V
F
L
A
K
--
K
D-
R
K
W
L
V
L
----------------------------------------------------------------------------------------------------------
6
HHSearch
46.19
20%
-32
- C2 -
4HZ9
-
?
B:
[82-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
V
D
Y
F
L
K
V
Q
D
Y
D
S
R
D
W
L
A
H
I
---
Q
V
Q
R
A
L
--
M
---
L
G
-
D
V
A
V
V
P
V
S
F
--
G
-
S
----
Q
D
----
P
V
----
H
V
L
--
V
F
L
K
R
--
V
D-
A
T
W
K
I
I
K
---------------------------------------------------------------------------------------------------------
4
HHSearch
43.80
11%
-61
- C2 -
3FKA
5
?
A:
[70-116]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
F
W
---
A
I
S
S
V
S
--
V
---
Q
G
D
-
I
A
M
L
H
V
E
N
--
D
-
W
A
G
--
M
-----
R
F
----
D
D
F
--
L
T
V
L
L
--
H
E-
G
S
W
R
I
V
S
K
V
-------------------------------------------------------------------------------------------------------
18
HHSearch
37.85
19%
4
- C3 -
4XA1
-
MARE1_HUMAN (first)
A:
[6-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
H
E
--
D
I
L
N
K
L
L
D
P
E
L
A
Q
S
E
R
T
E
A
L
Q
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
37.78
26%
-61
- C2 -
3KZT
4
?
A:
[104-138]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Y
E
V
N
Y
--
T
-
S
A
K
--
G
S
QY
E
R
A
V
----
S
I
P
--
V
R
V
V
N
--
V
D-
G
Q
Y
L
I
D
D
---------------------------------------------------------------------------------------------------------
9
HHSearch
37.57
15%
-3
- C2 -
2OWP
1
?
A:
[77-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
T
--
T
---
F
G
T
D
F
A
T
V
S
T
E
F
--
T
-
S
D
A
--
T
P
---
L
L
G
----
R
Q
M
--
Q
T
W
A
R
L-
S
PA
D
G
W
K
I
V
A
A
H
V
S
L
----------------------------------------------------------------------------------------------------
13
HHSearch
36.27
15%
-11
- C2 -
4FCZ
-
?
B:
[115-164]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
I
---
T
V
D
P
A
K
--
A
---
D
D
G
K
R
A
S
V
G
M
K
V
--
T
-
G
N
N
--
G
A
----------
V
Y
P
--
V
Q
Y
T
L
EN
I
G-
G
E
W
K
V
R
N
V
I
V
------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
29.64
42%
26
- C1 -
2V73
1
?
A:
[127-154]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
V
K
T
V
S
D
P
N
I
K
F
L
N
A
I
N
L
N
S
G
F
I
G
K
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
28.01
13%
32
* C3 *
2KI0
-
?
A:
[1-36]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
G
Q
V
R
T
I
W
V
G
G
T
P
E
E
L
K
K
L
K
E
E
A
K
K
A
N
I
-
R
V
T
F
W
G
---
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
21.85
13%
-11
- C2 -
4OVM
-
?
A:
[122-137]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
L
G
K
--
R
D-
G
A
W
L
V
E
A
Y
H
-------------------------------------------------------------------------------------------------------