@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2432c: (2016-05-10 )
MTVRAEHCRGAGGCDECPSVMPEHPTALFHDVAAIALAQPGAEPGAMMGFPCRPALLPHLSRAVMRCVRTRSASTSLGVSVIAGQLPAAGSRHRLGAPCRHVRWWLASDGHWGMVSYIPTALNVSMGGIVGWRCVP
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20.-----.-......30.....----.---..40........50--..---..-----.....60........70........80........90........100.......110....--...120.....-..-130....-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTV
R
A
E
HCRGAG
G
C
D
E
C
P
SVMP-----E-H
P
T
A
L
F
H
D
V
A
A
I
A
----L---AQPGAEPGAMMGF---PC---
R
P
-----
A
L
L
P
H
L
S
R
A
V
M
R
C
V
R
TRSASTSL
G
V
S
VIAGQLPAAGSRHRLGAPCR
H
V
R
W
W
LASDGHW
G
M
V
S
--YI
P
T
A
L
N
V
SMG-
G
I
-
V
G
W
R
CVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
69.83
23%
-79
* C11 *
5A1F
14
KDM5B_HUMAN
A:
[1-458]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S
M
F
L
P
P
P
---------
E
C
P
V
F
E
P
S
WEEF
A
-
D
P
F
A
F
I
H
K
I
R
P
I
A
E
Q
T
G
I
---
C
K
V
R
P
P
P
D
W
Q
P
P
F
---
A
C
D
VD
K
L
-----
H
F
T
P
R
I
Q
R
L
N
E
L
E
A
Q
T
R
V
R
D
Y
T
L
---
R
T
F
G
E
M
A
D
A
F
K
S
D
Y
F
N
M
P
V
H
M
V
P
T
E
L
V
E
K
E
F
W
R
L
V
S
--
T
I
E
E
D
V
T
V
E
Y
G
-
A
D
-
I
A
S
K
E
F
G
SG
F
P
V
R
DS
P
E
E
E
E
Y
L
D
SGWNLNNMPVMEQSVLAHITADICGMK
L
P
W
L
Y
V
G
M
CFSSF
C
W
H
I
E
DHW
S
Y
S
I
N
Y
L
HW
G
E
P
K
T
W
Y
G
V
P
GYA
A
E
Q
L
E
N
V
M
K
K
L
APELFVSQPDLL
H
Q
L
V
T
I
M
N
P
N
T
L
M
T
H
EV
P
V
Y
R
T
N
Q
C
AG
E
F
V
I
T
F
P
R
A
Y
H
S
G
F
N
Q
G
F
N
F
A
E
A
V
N
F
C
T
VDW
L
P
L
G
R
Q
C
V
E
H
Y
R
L
L
HRYCVFS
H
D
E
M
I
C
K
M
A
S
K
ADVLD
V
V
V
A
S
T
V
Q
K
D
M
A
I
M
I
E
D
E
K
A
L
R
E
T
V
R
K
L
GVI
D
S
E
R
M
DFELLPDDERQCVKCKTTCFM
S
A
I
S
C
SCKPG
L
L
V
C
LHHVKELCSCPPYKYKLRYRYT
L
D
D
L
Y
P
M
M
N
A
L
K
L
R
A
E
33
Fugue
66.38
15%
-94
- C8 -
1Q77
-
Y178_AQUAE
A:
[1-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNAM
K
V
L
L
V
L
T
D
A
Y
----
S
D
C
E
K
A
I
T
Y
A
V
-----
N
-
F
S
E
K
L
G
A
E
L
D
I
L
A
----
V
L
E
D
V
Y
N
L
E
R
A
N
V
T
F
G
L
---
P
F
---
P
P
-----
E
I
K
E
E
S
K
K
R
I
E
R
R
L
R
E
V
W
E
K
L
T
-------
G
S
T
E
I
P
G
V
E
Y
R
I
G
P
L
S
E
E
V
K
K
F
V
E
G
K
G
Y
E
L
V
V
W
A
C
Y
P
S
A
Y
L
C
K
V
I
D
-
G
L
N
L
A
S
L
I
V
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
58.58
19%
-105
* C10 *
1ZLD
2
?
A:
[19-118]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
I
G
Q
V
D
I
D
S
V
I
----
L
---
G
R
P
G
A
----
I
G
S
W
---
E
L
---
N
N
-----
F
I
T
I
G
L
N
R
V
N
A
D
T
V
R
V
N
I
R
N
T
G
R
T
N
R
L
I
I
T
Q
W
D
N
T
V
T
R
G
D
V
Y
E
L
F
----------
G
D
Y
A
L
I
Q
G
-
R
G
S
F
C
L
N
I
R
S
D
T
G
R
-
E
N
W
R
M
Q
L
EN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
57.70
17%
-73
- C6 -
4KRT
10
?
A:
[7-353]
H
H
H
H
H
M
Q
SRNNN
N
L
K
G
I
D
V
S
NWKGNIN
F
E
S
V
K
N
D
GVE
V
V
Y
I
K
A
T
EGNYFKDKY
A
K
Q
N
Y
E
G
A
K
E
Q
G
L
S
V
G
F
Y
H
FFRANKG
A
K
D
Q
A
N
F
F
I
D
Y
L
N
E
I
GAVNYDCKLALDIETTEGVG
V
R
D
L
T
S
M
C
I
E
F
L
E
E
V
K
R
L
T
G
K
E
V
V
V
Y
T
Y
T
S
F
A
N
N
NLDSRLGNYPVW
I
A
H
Y
GVNTPGANNIWSSWVGF
Q
Y
S
E
N
G
S
V
A
G
V
N
G
----
G
C
D
M
N
-----
E
-
F
T
E
E
I
F
I
D
S
S
----------------------
N
F
---
N
L
---
D
N
-----
A
T
T
K
N
V
S
T
K
L
N
--
I
R
A
K
G
T
T
N
S
K
----
I
I
G
S
I
P
A
G
E
T
F
K
I
K
W
V
D
E
D
Y
L
G
W
Y
Y
V
E
Y
N
--
G
V
V
G
--
Y
V
N
A
D
Y
V
E
K
L
Q
-
M
A
-
T
T
Y
N
V
S
T
F
L
N
V
R
EEGSLNSRIV
D
K
I
N
SG
D
I
F
R
IDWVDSDFIGWYRITTKNG
K
V
G
F
V
N
AEFVKKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
53.04
18%
-75
- C11 -
2MN4
-
?
A:
[1-94]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
P
E
Q
R
--------
E
F
L
P
E
I
L
A
-----
E
-
I
I
A
N
L
D
P
T
K
I
L
E
E
----
L
---
L
R
R
G
-------------------------
L
L
T
P
A
E
L
Q
E
V
L
D
L
K
T
P
E
E
Q
A
K
K
L
I
D
F
I
L
-
K
L
S
P
A
D
V
Q
A
R
I
N
V
L
R
A
H
--------
G
Y
Q
A
L
A
D
--
K
L
N
K
Y
L
T
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
49.24
12%
-74
- C7 -
1F16
-
BAX_HUMAN
A:
[1-192]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
G
S
G
E
Q
P
R
G
G
G
P
T
S
--
S
E
Q
I
M
-----
K
-
T
G
A
L
L
L
Q
G
F
I
Q
D
R
----
A
---
G
R
M
G
G
E
A
P
E
L
A
--LDP
V
P
---
Q
D
-----
A
S
T
K
K
L
S
E
C
L
K
R
I
G
D
E
L
D
S
--
N
M
E
L
Q
R
M
I
A
A
V
D
T
--
D
S
P
R
E
V
F
F
R
V
A
A
D
M
F
S
D
G
N
F
N
W
G
R
V
V
--
A
L
F
Y
F
A
S
K
L
V
L
-
K
A
-
L
C
T
K
V
P
E
L
I
R
T
I
M
G
W
T
L
D
F
L
R
E
RLL
G
W
I
Q
D
Q
GGW
D
G
L
L
S
Y
F
GTPTW
Q
T
V
T
I
F
V
A
G
V
L
T
A
S
L
T
I
WKKMG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
48.09
8%
-96
- C10 -
3C19
2
?
A:
[2-178]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SL
G
L
D
Y
E
PS
H
L
M
F
L
V
T
V
L
D
D
R
D
G
E
V
L
G
D
A
I
Q
-----
K
L
I
E
R
E
E
V
L
A
C
H
A
V
P
----
C
---
V
T
K
K
N
R
P
G
H
V
L
V
V
---
L
V
---
D
G
GED
P
D
R
V
A
E
D
V
A
R
D
I
M
V
L
T
G
S
T
G
V
D
R
F
D
A
D
G
V
Y
S
V
P
S
R
F
E
D
V
R
V
V
Y
G
E
R
E
W
R
V
S
V
K
I
A
E
T
E
E
G
E
V
V
T
--
V
K
A
E
F
D
E
C
R
E
I
-
G
E
-
E
T
G
I
P
P
R
E
V
K
A
M
V
E
A
A
A
R
V
GGWVDLKER
E
I
K
V
Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.18
29%
-68
* C12 *
2NN6
-
EXOS9_HUMAN
A:
[76-160]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
F
N
L
E
L
S
Q
----
M
---
A
A
P
A
F
E
P
G
R
------------
Q
S
-----
D
L
L
V
K
L
N
R
L
M
E
R
C
L
R
N
S
K
C
I
D
T
E
S
L
C
V
V
A
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
41.00
29%
-41
- C13 -
1XLQ
1
PUTX_PSEPU
A:
[38-54]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
G
G
S
A
S
C
A
T
C
H
V
Y
V
N
-----
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
40.59
31%
-49
- C13 -
3HUI
1
?
A:
[59-74]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
C
G
G
A
C
A
C
A
T
C
H
V
Y
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
40.06
24%
5
- C13 -
1B9R
1
TERPB_PSESP
A:
[38-54]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
C
G
G
S
C
V
C
A
T
C
R
I
E
I
E
-----
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
39.83
25%
14
- C5 -
2MJD
1
A:
[40-55]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
G
G
S
C
A
C
S
T
C
H
V
I
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
39.62
31%
-35
- C13 -
1UWM
1
FER6_RHOCA
A:
[38-53]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
G
G
A
C
A
C
S
T
C
H
A
Y
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
38.69
24%
-41
- C13 -
1I7H
1
FER_ECOLI
A:
[41-57]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
E
K
S
C
A
C
T
T
C
H
C
I
V
R
-----
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
38.21
24%
-43
- C13 -
3AH7
2
?
A:
[41-57]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
G
G
V
K
A
C
T
T
C
H
C
I
V
R
-----
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
37.72
25%
-36
- C13 -
4LTU
1
?
A:
[39-54]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
C
G
G
N
A
V
C
A
T
C
H
V
Y
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
37.61
24%
11
- C13 -
1L5P
1
FER_TRIVA
A:
[37-53]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
C
Q
G
N
K
A
C
G
K
C
I
C
K
H
V
-----
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
37.40
25%
-31
- C13 -
2WLB
1
ETP1_SCHPO
A:
[40-55]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
E
G
S
V
A
C
S
T
C
H
V
I
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
36.64
20%
-18
- C13 -
2Y5C
1
ADXL_HUMAN
A:
[42-56]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
E
A
S
L
A
C
S
T
C
H
V
Y
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
35.22
24%
1
- C13 -
3LXF
1
?
A:
[38-54]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
G
G
C
C
S
C
A
T
C
H
V
L
V
A
-----
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------