@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2445c: (2016-05-10 )
MTERTLVLIKPDGIERQLIGEIISRIERKGLTIAALQLRTVSAELASQHYAEHEGKPFFGSLLEFITSGPVVAAIVEGTRAIAAVRQLAGGTDPVQAAAPGTIRGDFALETQFNLVHGSDSAESAQREIALWFPGA
Atome Classification :
(99 SA)
-.........10........20........30........40.........50........60........70........80........90.......---.100.......110---.......120.......130....--------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MT
E
R
T
L
V
L
IKPDG
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
RKG
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
HEGK
P
F
F
G
S
L
L
E
F
ITSG
P
V
V
A
A
I
VEG
T
R
A
I
A
A
V
R
Q
LAGGTDPVQAA---APGTIRG
D
F
A
L
E
T
Q
---
F
N
L
V
HGSDS
A
E
S
AQ
R
E
I
A
L
WFPGA--------------
113
HHSearch
96.97
99%
-118
- C7 -
4ANE
1
NDK_MYCTU
A:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
4
PsiBlast_PDB
96.96
99%
-118
- C7 -
4ANE
1
NDK_MYCTU
A:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
1
PsiBlast_PDB
96.56
100%
-124
- C7 -
1K44
-
NDK_MYCTU
A:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
R
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
3
PsiBlast_PDB
95.27
99%
-124
- C7 -
4AND
-
NDK_MYCTU
A:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
R
A
I
A
A
V
R
Q
L
A
G
G
T
N
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
22
PsiBlast_CBE
93.80
99%
-121
- C7 -
4ANE
1
NDK_MYCTU
D:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
----
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
2
PsiBlast_PDB
92.43
99%
-123
- C7 -
4ANC
-
NDK_MYCTU
A:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
R
A
I
A
A
V
R
Q
L
A
G
G
T
N
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
21
PsiBlast_CBE
90.37
99%
-119
- C7 -
4ANE
1
NDK_MYCTU
F:
[2-136]
--
T
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
--------
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
---
A
P
G
T
I
R
G
D
F
A
L
E
T
Q
---
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------------
5
PsiBlast_PDB
85.01
59%
-119
- C7 -
3VVT
-
?
A:
[2-131]
---
E
R
T
F
V
M
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
S
R
F
E
R
K
G
L
K
I
V
A
M
K
M
M
R
-
I
S
R
E
M
A
E
K
H
Y
A
E
H
R
E
K
P
F
F
S
A
L
V
D
Y
I
T
S
G
P
V
V
A
M
V
L
E
G
K
N
A
V
E
V
V
R
K
M
V
G
A
T
N
P
-
K
E
A
---
A
P
G
T
I
R
G
D
F
G
L
D
V
G
---
K
N
V
I
H
A
S
D
S
P
E
S
A
E
R
E
I
S
L
F
F
-----------------
39
PsiBlast_CBE
84.90
55%
-116
- C7 -
3Q8U
2
NDK_STAAC
F:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
41
PsiBlast_CBE
84.73
55%
-115
- C7 -
3Q8U
2
NDK_STAAC
D:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
26
PsiBlast_CBE
84.70
56%
-116
- C7 -
2DXF
1
NDK_PYRHO
B:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
46
PsiBlast_CBE
84.48
55%
-114
- C7 -
3Q86
1
NDK_STAAC
B:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
28
PsiBlast_CBE
84.46
56%
-117
- C7 -
2DXD
2
NDK_PYRHO
B:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
25
PsiBlast_CBE
84.39
56%
-116
- C7 -
2DY9
2
NDK_PYRHO
B:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
8
PsiBlast_PDB
84.37
59%
-116
- C7 -
1WKK
1
NDK_THET8
A:
[2-131]
---
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
---
L
P
G
T
I
R
G
D
F
A
T
T
I
D
---
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
-----------------
15
PsiBlast_PDB
84.34
56%
-113
- C7 -
2DYA
3
NDK_PYRHO
A:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
24
PsiBlast_CBE
84.32
56%
-117
- C7 -
2DYA
4
NDK_PYRHO
B:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
10
PsiBlast_PDB
84.28
56%
-120
- C7 -
2CWK
-
NDK_PYRHO
A:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
31
PsiBlast_CBE
84.26
55%
-119
- C7 -
3Q8Y
1
NDK_STAAC
F:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
16
PsiBlast_PDB
84.21
55%
-115
- C7 -
3Q83
-
NDK_STAAC
A:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
9
PsiBlast_PDB
84.13
59%
-119
- C7 -
1WKL
2
NDK_THET8
A:
[2-131]
---
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
---
L
P
G
T
I
R
G
D
F
A
T
T
I
D
---
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
-----------------
13
PsiBlast_PDB
83.91
56%
-119
- C7 -
2DXF
2
NDK_PYRHO
A:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
30
PsiBlast_CBE
83.89
55%
-116
- C7 -
3Q8Y
2
NDK_STAAC
G:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
11
PsiBlast_PDB
83.79
56%
-118
- C7 -
2DXD
2
NDK_PYRHO
A:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
19
PsiBlast_PDB
83.55
55%
-116
- C7 -
3Q8U
2
NDK_STAAC
A:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
40
PsiBlast_CBE
83.52
55%
-114
- C7 -
3Q8U
2
NDK_STAAC
E:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
12
PsiBlast_PDB
83.47
56%
-116
- C7 -
2DXE
2
NDK_PYRHO
A:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
37
PsiBlast_CBE
83.40
55%
-121
- C7 -
3Q8V
2
NDK_STAAC
D:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
35
PsiBlast_CBE
83.26
55%
-118
- C7 -
3Q8Y
2
NDK_STAAC
B:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
42
PsiBlast_CBE
83.17
55%
-115
- C7 -
3Q8U
1
NDK_STAAC
C:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
45
PsiBlast_CBE
83.13
55%
-119
- C7 -
3Q89
2
NDK_STAAC
B:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
14
PsiBlast_PDB
83.13
56%
-115
- C7 -
2DY9
3
NDK_PYRHO
A:
[7-140]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
---
A
P
G
T
I
R
G
D
F
G
L
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
-----------------
33
PsiBlast_CBE
83.11
55%
-114
- C7 -
3Q8Y
3
NDK_STAAC
D:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
38
PsiBlast_CBE
82.94
55%
-118
- C7 -
3Q8V
2
NDK_STAAC
B:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
44
PsiBlast_CBE
82.89
55%
-117
- C7 -
3Q89
2
NDK_STAAC
E:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
36
PsiBlast_CBE
82.62
55%
-115
- C7 -
3Q8Y
2
NDK_STAAC
A:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
29
PsiBlast_CBE
82.57
55%
-118
- C7 -
3Q8Y
3
NDK_STAAC
H:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
20
PsiBlast_PDB
82.41
55%
-114
- C7 -
3Q8V
2
NDK_STAAC
A:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
43
PsiBlast_CBE
82.37
55%
-115
- C7 -
3Q8U
2
NDK_STAAC
B:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
17
PsiBlast_PDB
82.23
55%
-111
- C7 -
3Q86
2
NDK_STAAC
A:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
23
PsiBlast_CBE
81.46
59%
-120
- C7 -
1WKL
2
NDK_THET8
B:
[2-131]
---
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
---
L
P
G
T
I
R
G
D
F
A
T
T
I
D
---
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
-----------------
32
PsiBlast_CBE
81.42
55%
-116
- C7 -
3Q8Y
2
NDK_STAAC
E:
[2-131]
---
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
---
S
P
G
S
I
R
G
D
L
G
L
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
-----------------
117
HHSearch
81.41
51%
-105
- C7 -
1NHK
1
NDK_MYXXA
R:
[2-134]
--
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
---
A
E
G
T
I
R
K
D
F
A
T
S
I
D
---
K
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
---------------
75
PsiBlast_CBE
80.15
53%
-110
- C7 -
1ZS6
1
NDK3_HUMAN
D:
[22-151]
---
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
-
A
---
P
P
G
T
I
R
G
D
F
C
I
E
V
G
---
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
-----------------
77
PsiBlast_CBE
79.61
53%
-117
- C7 -
1ZS6
1
NDK3_HUMAN
A:
[22-151]
---
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
-
A
---
P
P
G
T
I
R
G
D
F
C
I
E
V
G
---
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
-----------------
60
PsiBlast_CBE
79.33
54%
-118
- C7 -
1HIY
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
102
Fugue
79.32
51%
-112
- C7 -
1NDP
1
NDKC_DICDI
A:
[6-155]
V
N
K
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
----
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
ELLT
E
V
K
P
NPNLYE
56
PsiBlast_CBE
79.08
54%
-114
- C7 -
1KDN
2
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
128
HHSearch
79.00
47%
-111
- C7 -
4FKX
1
?
A:
[11-143]
--
S
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
N
L
V
G
E
I
I
K
R
F
E
N
K
G
Y
K
L
V
G
L
K
L
L
Q
-
P
T
E
E
Q
A
K
Q
H
Y
I
D
L
A
S
K
P
F
Y
S
G
L
V
S
Y
F
S
S
G
P
I
V
G
M
V
W
E
G
L
G
V
V
K
G
G
R
V
L
L
G
A
T
N
P
A
D
-
S
---
L
P
G
T
I
R
G
D
F
A
V
D
V
G
---
R
N
V
C
H
G
S
D
S
V
E
S
A
K
R
E
I
A
F
W
F
K
A
---------------
89
PsiBlast_CBE
78.96
53%
-121
- C7 -
3FKB
5
NDKC_DICDI
D:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
54
PsiBlast_CBE
78.95
54%
-114
- C7 -
1NDP
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
76
PsiBlast_CBE
78.89
53%
-112
- C7 -
1ZS6
1
NDK3_HUMAN
B:
[22-151]
---
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
-
A
---
P
P
G
T
I
R
G
D
F
C
I
E
V
G
---
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
-----------------
96
PsiBlast_CBE
78.79
53%
-117
- C7 -
1F3F
1
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
47
PsiBlast_CBE
78.68
54%
-113
- C7 -
2BEF
2
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
58
PsiBlast_CBE
78.52
54%
-113
- C7 -
1KDN
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
124
HHSearch
78.28
47%
-109
- C7 -
3EVO
1
NDK_MIMIV
A:
[6-138]
--
L
Q
R
T
L
V
L
I
K
P
D
A
F
E
R
S
L
V
A
E
I
M
G
R
I
E
K
K
N
F
K
I
V
S
M
K
F
W
S
K
A
P
R
N
L
I
E
Q
H
Y
K
E
H
S
E
Q
S
Y
F
N
D
N
C
D
F
M
V
S
G
P
I
I
S
I
V
Y
E
G
T
D
A
I
S
K
I
R
R
L
Q
G
N
T
N
P
L
A
-
S
---
A
P
G
T
I
R
G
D
L
A
N
D
I
R
---
E
N
L
I
H
A
S
D
S
E
D
S
A
V
D
E
I
S
I
W
F
P
----------------
99
PsiBlast_CBE
78.00
53%
-113
- C7 -
1B4S
3
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
67
PsiBlast_CBE
77.91
54%
-116
- C7 -
1BUX
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
55
PsiBlast_CBE
77.88
54%
-118
- C7 -
1NDC
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
53
PsiBlast_CBE
77.67
54%
-116
- C7 -
1NDP
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
93
PsiBlast_CBE
77.65
53%
-117
- C7 -
1MN9
2
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
57
PsiBlast_CBE
77.64
54%
-115
- C7 -
1KDN
2
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
61
PsiBlast_CBE
77.57
54%
-113
- C7 -
1HIY
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
88
PsiBlast_CBE
77.45
53%
-117
- C7 -
3FKB
2
NDKC_DICDI
E:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
92
PsiBlast_CBE
77.41
53%
-116
- C7 -
3FKB
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
66
PsiBlast_CBE
77.31
54%
-117
- C7 -
1BUX
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
87
PsiBlast_CBE
77.30
53%
-116
- C7 -
3FKB
2
NDKC_DICDI
F:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
90
PsiBlast_CBE
77.29
53%
-120
- C7 -
3FKB
2
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
59
PsiBlast_CBE
77.24
54%
-117
- C7 -
1HIY
1
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
80
PsiBlast_CBE
77.21
53%
-114
- C7 -
1LWX
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
A
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
94
PsiBlast_CBE
77.19
53%
-116
- C7 -
1MN9
2
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
49
PsiBlast_CBE
77.17
54%
-109
- C7 -
2BEF
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
95
PsiBlast_CBE
77.16
53%
-117
- C7 -
1MN9
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
85
PsiBlast_CBE
77.11
53%
-118
- C7 -
4CP5
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
71
PsiBlast_CBE
77.05
54%
-113
- C7 -
1B99
1
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
91
PsiBlast_CBE
76.92
53%
-118
- C7 -
3FKB
2
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
63
PsiBlast_CBE
76.73
54%
-112
- C7 -
1F6T
2
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
101
PsiBlast_CBE
76.55
53%
-114
- C7 -
1B4S
3
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
82
PsiBlast_CBE
76.55
53%
-116
- C7 -
4CP5
1
NDKC_DICDI
E:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
65
PsiBlast_CBE
76.52
54%
-114
- C7 -
1BUX
1
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
52
PsiBlast_CBE
76.41
54%
-119
- C7 -
1S5Z
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
81
PsiBlast_CBE
76.34
53%
-116
- C7 -
4CP5
1
NDKC_DICDI
F:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
97
PsiBlast_CBE
76.27
53%
-113
- C7 -
1F3F
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
98
PsiBlast_CBE
76.18
53%
-112
- C7 -
1F3F
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
79
PsiBlast_CBE
76.18
53%
-115
- C7 -
1LWX
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
A
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
72
PsiBlast_CBE
76.14
54%
-113
- C7 -
1B99
1
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
68
PsiBlast_CBE
76.12
54%
-110
- C7 -
1B99
1
NDKC_DICDI
F:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
64
PsiBlast_CBE
76.05
54%
-113
- C7 -
1F6T
2
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
83
PsiBlast_CBE
75.93
53%
-117
- C7 -
4CP5
1
NDKC_DICDI
D:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
84
PsiBlast_CBE
75.80
53%
-115
- C7 -
4CP5
1
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
73
PsiBlast_CBE
75.71
54%
-111
- C7 -
1B99
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
48
PsiBlast_CBE
75.71
54%
-117
- C7 -
2BEF
2
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
78
PsiBlast_CBE
75.69
53%
-111
- C7 -
1LWX
2
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
A
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
69
PsiBlast_CBE
75.53
54%
-113
- C7 -
1B99
1
NDKC_DICDI
E:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
86
PsiBlast_CBE
75.52
53%
-115
- C7 -
4CP5
1
NDKC_DICDI
A:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
70
PsiBlast_CBE
75.45
54%
-114
- C7 -
1B99
1
NDKC_DICDI
D:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
62
PsiBlast_CBE
75.26
54%
-113
- C7 -
1F6T
2
NDKC_DICDI
C:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
100
PsiBlast_CBE
74.82
53%
-110
- C7 -
1B4S
3
NDKC_DICDI
B:
[9-138]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
-
A
S
---
A
P
G
S
I
R
G
D
F
G
V
D
V
G
---
R
N
I
I
G
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
-----------------
114
HHSearch
73.68
45%
-100
- C7 -
3ZTP
2
NDK_AQUAE
A:
[2-138]
-
A
V
E
R
T
L
I
I
V
K
P
D
A
M
E
K
G
A
L
G
K
I
L
D
R
F
I
Q
E
G
F
Q
I
K
A
L
K
M
F
R
-
F
T
P
E
K
A
G
E
F
Y
Y
V
H
R
E
R
P
F
F
Q
E
L
V
E
F
M
S
S
G
P
V
V
A
A
V
L
E
G
E
D
A
I
K
R
V
R
E
I
I
G
P
T
D
S
E
E
-
A
R
K
V
A
P
N
S
I
R
A
Q
F
G
T
D
K
G
---
K
N
A
I
H
A
S
D
S
P
E
S
A
Q
Y
E
I
C
F
I
F
S
G
---------------