@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2481c: (2016-05-11 )
MALRRRHEPDGWPFSQRSEKPNAVRHAVRCSAVSAAASTANGTPVNWVSGRVTRAMGVHRQTRGGVASVHADSLRGAVLVHGQLRNSIPISANVPASGANTKSSIAH
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10------------------......-...20.-...--....30........40-.......-..50...-.....60........70-----------........-80.......----.90........100.....------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRRRHEPD-------------------GWPFSQ-RSEK
P
N
-
A
V
R
--
H
A
V
R
C
S
A
VSAAASTA--NGTPVNW-VSG
R
V
T
R
-
A
MGVHRQTRG
G
V
A
S
VHA-----------DSLR
G
A
V
L
-
V
H
GQLRNSI----PISANVPASGANTKSSIAH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
78.66
20%
-34
- C12 -
4IUW
16
?
A:
[4-633]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPRIQDD
L
Y
L
A
V
N
G
E
W
Q
A
K
T
P
I
P
P
D
-------------------
K
S
V
V
S
A
-
D
S
N
L
T
D
-
D
I
R
--
Q
K
L
V
A
D
L
-
S
T
M
T
K
T
A
--
K
T
L
P
L
Q
Y
-
A
A
R
L
F
A
K
-
A
N
D
Q
T
R
R
Q
Q
L
G
I
E
P
V
R
D
R
I
S
F
L
M
A
LTT
L
D
Q
F
R
S
A
M
P
-
K
L
V
A
D
Q
Y
V
L
----
P
I
S
P
Y
V
D
A
D
M
H
D
A
E
H
N
I
L
N
L
G
G
P
D
T
ILPD
A
A
M
Y
N
Q
ED
A
E
N
A
A
D
L
A
A
W
S
Q
M
A
A
A
M
L
A
A
V
GFS
Q
T
D
Q
T
A
Y
V
E
A
A
K
R
F
D
R
R
L
A
D
Y
VPA
N
V
D
L
A
VDSTYD
N
P
L
S
W
Q
A
F
E
D
A
AGYLG
I
P
Q
A
F
A
T
Y
MPQTPA
K
V
N
A
VVPAYLPH
L
S
K
L
L
TPDN
Y
S
E
W
H
A
W
M
V
I
N
E
L
L
T
C
A
T
Y
L
S
D
D
L
R
Q
L
A
G
Q
Y
D
R
F
L
A
GQPEASS
W
T
K
H
A
F
G
I
A
N
E
YF
D
D
V
I
G
Q
Y
Y
G
Q
T
YFG
A
D
A
K
A
D
V
T
A
M
V
K
Q
I
L
A
Q
Y
R
V
Q
L
E
N
NTWLS
P
A
T
K
Q
K
A
M
R
K
L
A
T
M
Q
V
K
M
GYPARLFSLYDH
L
S
V
D
VDDD
L
L
T
A
I
L
K
L
S
A
Q
T
Q
A
F
W
F
K
Q
L
GQTVDRNQWNMPGHLV
N
A
S
Y
D
PLKN
D
I
T
F
P
AGILQPPYYSLKWT
R
A
E
N
L
G
G
T
G
A
T
I
G
H
E
I
S
H
S
F
D
N
N
G
A
L
Y
DEYGNLHNWWT
P
A
D
K
Q
A
F
D
Q
L
V
K
A
M
A
A
Q
F
DGRDYEG
V
K
V
N
GTLT
V
S
E
N
M
A
D
N
A
G
M
D
V
A
L
A
L
L
GDQPD
V
K
D
L
Q
A
F
F
I
T
Y
A
R
S
W
A
T
K
M
R
P
E
R
A
K
T
V
L
R
QDVHAP
A
T
L
R
V
N
V
P
V
Q
N
F
P
A
W
Y
Q
A
F
NVQPQDGMYRQPQK
R
L
T
I
WHQ
23
Fugue
78.59
22%
-72
- C6 -
4RNZ
9
?
A:
[1-369]
M
E
R
L
V
W
D
KLT
L
L
G
F
L
E
K
N
HIPQ
K
L
Y
Y
N
LS
S
Q
D
K
E
L
S
A
E
IQSN
V
T
Y
Y
T
L
R
D
ANNTLI
Q
A
L
I
P
ISQD
L
Q
I
H
I
Y
K
K
GE
D
Y
F
L
D
F
I
P
I
I
F
T
R
K
E
K
T
L
L
L
S
L
QTS
P
Y
Q
D
I
I
K
A
TND
P
L
L
A
N
Q
L
M
N
A
Y
K
KS
V
P
F
K
R
LVKN
D
K
I
A
I
V
Y
T
R
D
Y
R
VGQAF
G
Q
P
T
I
K
M
A
M
V
S
S
RS
N
Q
Y
Y
L
F
S
H
SNG
H
Y
Y
D
SKAQEVAGFL
L
E
T
P
V
K
Y
T
R
I
-------------------
S
S
P
F
S
Y
G
R
F
H
R
P
H
Y
G
V
D
--
Y
A
A
K
-------------
H
G
S
L
I
H
S
-
A
S
D
G
R
V
G
-
F
M
G
V
K
A
G
Y
-
G
K
V
V
E
I
H
L
-----------
N
E
L
R
L
V
Y
A
-
H
M
S
A
F
A
N
G
L
----
K
K
G
S
F
V
K
-----
K
G
Q
I
I
G
R
V
G
STG
P
H
L
H
F
G
V
Y
K
NSRPINPLGYIRT
A
K
S
K
L
H
G
K
Q
R
E
V
F
L
E
K
A
Q
R
S
K
Q
K
L
E
E
L
L
K
T
H
SFEKNSFYLLEGFLEHHHH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
73.31
17%
-23
- C9 -
3HA4
-
?
A:
[17-143]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E
E
L
E
A
Q
R
Q
R
H
N
D
P
R
-------------------
R
P
P
W
P
L
-
L
H
Q
R
V
V
-
L
L
R
E
G
K
G
A
P
E
D
I
A
L
M
W
E
Q
T
K
--
H
Y
Y
P
A
D
W
L
I
P
L
E
L
T
Q
-
V
L
K
Y
S
S
G
K
Y
L
Q
T
Y
V
A
D
P
-----------
D
E
M
R
K
E
V
L
-
M
--
Q
L
L
N
V
K
----
Y
G
R
V
S
D
P
N
G
G
R
V
N
K
D
V
E
E
I
I
S
M
A
V
D
D
L
E
N
MDLNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
71.04
21%
-24
* C11 *
4YDD
9
?
B:
[5-333]
-------------------------------------------MKAPRRQL
T
Y
V
T
D
LNKCIGCQ
T
C
T
V
A
C
K
K
L
WTTGPGQDFMYW
R
N
V
E
T
A
PGLGYPRNWQTKGGGYKNG
E
L
Q
K
G
K
I
P
P
MIDYGIPFEFD
Y
A
G
R
L
FEG
K
P
G
R
VRPSPTPRSAPNWDEDQ
G
A
G
E
Y
PN
N
S
F
F
Y
L
P
R
M
CNHCTKP
A
C
L
E
A
CPN
E
A
I
Y
K
R
-
E
Q
D
-------------------
G
-----------
I
-
V
V
I
--
H
Q
D
K
C
K
G
A
Q
A
C
V
Q
S
C
PY
A
K
P
Y
F
N
P
-
L
T
N
K
A
N
K
-
C
I
G
C
F
P
R
I
E
Q
G
V
A
P
A
C
V
-----------
A
Q
C
V
G
R
A
M
-
H
V
G
F
V
D
D
------------------
V
N
S
S
V
Y
K
L
I
KQYKV
A
L
P
L
HPEFGTEPN
V
F
Y
VPPV
L
G
P
R
IEMANGEPSTDPKIP
L
A
Q
L
E
G
L
FGKQ
V
R
D
V
L
A
I
L
Q
S
E
R
E
K
K
M
K
GLAS
D
L
M
D
V
L
I
GRRSTDMMISPLT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
70.88
14%
-37
- C12 -
2KL8
-
?
A:
[1-85]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
M
D
I
R
F
R
G
D
-----------------------------
D
L
E
-
A
F
E
--
K
A
L
K
--
E
M
I
R
Q
A
R
K
F
--
A
G
T
V
T
Y
T
-
L
D
G
N
------
D
L
E
I
R
I
T
G
V
P
E
Q
V
R
K
-----------
E
L
A
K
E
A
E
R
-
L
A
K
E
F
N
I
T
V
----
T
Y
T
I
R
L
E
H
H
H
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
68.57
23%
-81
- C11 -
2JX5
-
?
A:
[1-69]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
V
I
V
R
L
Q
D
--
Q
T
L
P
F
E
L
-
P
A
G
A
R
A
S
-
Q
L
S
N
L
L
S
S
S
G
M
A
F
S
L
H
T
--------------
Q
G
R
V
L
S
E
A
A
E
L
N
D
K
M
----
V
I
D
A
F
V
P
A
D
G
A
G
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
62.99
32%
-34
- C8 -
5HMC
3
?
A:
[71-128]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
T
V
V
G
V
S
N
S
T
D
--
F
F
A
P
A
T
V
-
A
D
G
R
L
T
S
T
A
L
P
V
H
R
G
A
T
Q
Q
V
W
S
V
E
T
-----------
V
D
A
A
G
R
L
V
-
A
R
G
Q
V
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.50
32%
-36
- C8 -
5HMB
2
?
A:
[71-128]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
T
V
V
G
V
S
N
S
T
D
--
F
F
A
P
A
T
V
-
A
D
G
R
L
T
S
T
A
L
P
V
H
R
G
A
T
Q
Q
V
W
S
V
E
T
-----------
V
D
A
A
G
R
L
V
-
A
R
G
Q
V
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
61.62
18%
-32
* C8 *
2LW3
-
MMPS4_MYCTU
A:
[51-140]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
L
T
Y
E
I
F
-------------------
G
----------
P
P
-
G
T
V
--
A
D
I
S
Y
F
D
V
N
S
E
P
Q
R
V
--
D
G
A
V
L
P
W
-
S
L
H
I
T
T
N
-
D
A
A
V
M
G
N
I
---
V
A
Q
G
N
S
-----------
D
S
I
G
C
R
I
T
-
V
D
G
K
V
R
A
E
R
----
V
S
N
E
V
N
A
Y
T
Y
C
L
V
K
S
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
59.00
13%
-21
* C9 *
2GQB
-
?
A:
[1-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
I
F
G
K
I
M
S
A
I
F
GDSAAASPGG
A
Q
A
P
A
T
T
G
A
A
G
T
A
-
P
T
A
P
Q
P
-
T
A
A
--
P
S
I
D
V
A
P
I
L
D
K
A
V
K
A
--
K
G
E
K
L
E
W
-
R
T
S
I
V
D
L
-
M
K
A
L
D
I
D
S
S
L
S
A
R
K
E
L
A
-----------
K
E
L
G
Y
S
G
D
-
M
N
D
S
A
S
M
N
I
W
L
H
K
Q
V
M
S
K
L
V
A
N
G
G
K
L
P
P
E
I
K
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
52.04
36%
6
- C11 -
2J9U
1
VPS36_YEAST
B:
[15-61]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
T
W
V
C
P
-
I
C
M
V
S
N
E
T
Q
G
E
------------------------
F
-
T
K
D
T
L
P
T
P
I
----
C
I
N
C
G
V
P
A
D
Y
E
L
T
K
S
S
I
N
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
51.80
18%
5
* C12 *
3STQ
-
?
A:
[-12-73]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
M
N
L
K
P
Q
-
T
L
M
--
V
A
I
Q
C
V
A
A
R
T
R
E
L
D
A
--
Q
-------------------
L
Q
N
D
D
P
Q
N
A
A
E
L
E
-----------
Q
L
L
V
G
Y
D
L
-
A
A
D
D
L
K
N
A
Y
----
E
Q
A
L
G
Q
Y
-
S
G
L
P
P
Y
D
R
L
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
50.91
24%
-26
- C7 -
3CM1
-
SSGB_THEFY
A:
[31-81]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
-
S
V
D
D
P
Y
-
A
I
R
--
A
A
F
H
V
G
-----------
D
D
E
P
V
E
W
-
I
F
A
R
E
L
L
-
T
V
G
I
I
R
E
T
G
E
G
D
V
R
I
W
P
-----------
S
Q
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.44
37%
-21
* C10 *
2K1M
-
MYPC3_HUMAN
A:
[2-44]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
G
-------------------
K
K
P
V
S
A
-
F
S
K
K
P
R
-
S
V
E
--
V
A
A
G
S
P
A
V
F
E
A
E
T
E
R
--
A
G
V
K
V
R
W
-
Q
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
37.14
17%
9
* C7 *
2CVB
-
?
A:
[142-182]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
K
V
Q
-
S
H
D
L
E
A
-
A
I
E
--
A
L
L
R
G
E
E
P
P
L
K
E
A
P
A
--
I
G
C
T
I
K
W
-
R
P
G
N
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
34.29
58%
140
- C5 -
1YW5
-
?
A:
[2-13]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
T
S
--
T
G
L
P
P
N
W
-
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
33.68
36%
74
- C10 -
1SZI
-
PLIN3_MOUSE
A:
[413-426]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
--
Q
N
T
P
A
M
W
-
L
V
G
P
F
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
7.09
57%
305
- C3 -
1NRZ
-
PTRB_KLEPN
A:
[12-18]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
I
H
G
Q
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
6.43
43%
291
- C2 -
1BLE
-
PTFB_BACSU
A:
[13-19]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-
I
H
G
Q
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
3.73
57%
260
- C4 -
1VSQ
1
?
C:
[15-21]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
I
H
G
Q
V
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------