@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2518c: (2016-05-11 )
MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90....-....100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MPKVGIAAQA
G
R
T
R
V
R
R
A
W
L
T
A
L
M
M
T
A
V
M
I
G
A
VACGSGRGPA
P
I
K
V
I
ADKGT
P
F
A
D
L
L
V
P
K
LTASVTDG
A
V
G
V
T
VDA
P
V
S
V
T
AAD
G
V
L
A
A
V
T
M
VN-DNGRPVAGRLSPDGLRWS
T
T
E
QLGYNR
R
Y
T
L
NATALGLGGA
A
T
R
Q
L
T
F
QTSSPA
H
L
T
M
P
Y
VMPGDG
E
V
V
GVGE
P
V
A
I
R
FDENIADRGAA
E
K
A
I
K
I
TTNPPV
E
G
A
F
Y
W
LNN
R
E
V
R
WR
P
E
HFWKPG
T
A
V
D
V
A
V
N
T
YGVDLGEGMFGEDN
V
Q
T
H
F
T
IG
D
E
V
I
A
TADDN
T
K
I
L
T
V
R
VN
G
E
V
V
K
SMPTSMGKDSTPTAN
G
I
Y
I
VGSR
Y
K
H
I
I
MDSSTYGVPVNSPNGYRTDV
D
W
A
T
Q
I
S
Y
S
G
V
F
V
HSAPWSVGAQGHTNTSHG
C
L
NVSPSN
A
Q
W
F
Y
D
HVKRG
D
I
V
E
V
V
N
T
VGGTLPGIDGLGDWNI
P
W
D
QWRAGNAKA
5
PsiBlast_PDB
98.54
100%
-95
- C5 -
4QTF
2
LDT2_MYCTU
A:
[1-349]
----------------------------------------------------------
V
P
K
L
T
A
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
-
D
N
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
N
A
T
A
L
G
L
G
G
A
A
T
R
Q
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
2
PsiBlast_PDB
98.18
100%
-93
- C5 -
4QR7
2
LDT2_MYCTU
A:
[3-351]
----------------------------------------------------------
V
P
K
L
T
A
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
-
D
N
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
N
A
T
A
L
G
L
G
G
A
A
T
R
Q
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
1
PsiBlast_PDB
97.28
100%
-91
- C5 -
3VYN
-
LDT2_MYCTU
A:
[60-406]
-----------------------------------------------------------
P
K
L
T
A
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
-
D
N
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
N
A
T
A
L
G
L
G
G
A
A
T
R
Q
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
--
4
PsiBlast_PDB
95.80
100%
-96
- C5 -
4QRB
1
LDT2_MYCTU
A:
[1-351]
--------------------------------------------------------
L
L
V
P
K
L
T
A
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
-
D
N
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
N
A
T
A
L
G
L
G
G
A
A
T
R
Q
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
------------
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
32
HHSearch
95.20
100%
-98
- C5 -
4QRB
1
LDT2_MYCTU
A:
[5-351]
------------------------------------------------------------
K
L
T
A
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
D
N
-
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
N
A
T
A
L
G
L
G
G
A
A
T
R
Q
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
------------
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
21
PsiBlast_CBE
94.42
100%
-90
- C5 -
4QRA
1
LDT2_MYCTU
B:
[9-352]
----------------------------------------------------------------
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
-
D
N
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
--------------
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
3
PsiBlast_PDB
94.10
100%
-92
- C5 -
4QRA
1
LDT2_MYCTU
A:
[8-352]
---------------------------------------------------------------
A
S
V
T
D
G
A
V
G
V
T
V
D
A
P
V
S
V
T
A
A
D
G
V
L
A
A
V
T
M
V
N
-
D
N
G
R
P
V
A
G
R
L
S
P
D
G
L
R
W
S
T
T
E
Q
L
G
Y
N
R
R
Y
T
L
-----------
T
R
Q
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
26
PsiBlast_CBE
85.73
100%
-90
- C5 -
4GSU
1
LDT2_MYCTU
B:
[12-279]
---------------------------------------------------------------------------------------------------------------------------------------------
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
16
PsiBlast_PDB
84.91
99%
-90
- C5 -
4HUC
9
LDT2_MYCTU
A:
[2-262]
----------------------------------------------------------------------------------------------------------------------------------------------------
M
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
33
HHSearch
84.59
100%
-87
- C5 -
3VYP
2
LDT2_MYCTU
A:
[2-269]
---------------------------------------------------------------------------------------------------------------------------------------------
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
14
PsiBlast_PDB
84.59
100%
-87
- C5 -
3VYP
2
LDT2_MYCTU
A:
[2-269]
---------------------------------------------------------------------------------------------------------------------------------------------
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
27
PsiBlast_CBE
84.21
100%
-88
- C5 -
3VYP
3
LDT2_MYCTU
B:
[3-266]
----------------------------------------------------------------------------------------------------------------------------------------------
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
---
13
PsiBlast_PDB
84.17
100%
-82
- C5 -
4GSU
2
LDT2_MYCTU
A:
[12-279]
---------------------------------------------------------------------------------------------------------------------------------------------
L
T
F
Q
T
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
23
PsiBlast_CBE
84.11
100%
-87
- C5 -
3TUR
6
LDT2_MYCTO
B:
[1-286]
--------------------------------------------------------------------------------------------------------------------------
R
R
Y
T
L
N
A
T
A
L
G
-----------------
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
25
PsiBlast_CBE
83.86
99%
-87
- C5 -
3U1P
1
LDT2_MYCTO
B:
[29-286]
------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
24
PsiBlast_CBE
83.86
99%
-87
- C5 -
3VAE
1
LDT2_MYCTO
B:
[29-286]
------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
22
PsiBlast_CBE
83.82
100%
-87
- C5 -
3U1Q
6
LDT2_MYCTO
B:
[29-286]
------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
7
PsiBlast_PDB
83.75
100%
-88
- C5 -
3U1Q
4
LDT2_MYCTO
A:
[4-286]
-----------------------------------------------------------------------------------------------------------------------------
T
L
N
---------------------
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
52
Fugue
83.61
100%
-88
- C5 -
3TUR
6
LDT2_MYCTO
A:
[29-286]
------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
12
PsiBlast_PDB
83.57
100%
-89
- C5 -
4GSR
3
LDT2_MYCTU
A:
[17-279]
--------------------------------------------------------------------------------------------------------------------------------------------------
S
S
P
A
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
A
6
PsiBlast_PDB
83.57
100%
-88
- C5 -
3TUR
6
LDT2_MYCTO
A:
[29-286]
------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
T
M
P
Y
V
M
P
G
D
G
E
V
V
G
V
G
E
P
V
A
I
R
F
D
E
N
I
A
D
R
G
A
A
E
K
A
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
N
N
R
E
V
R
W
R
P
E
H
F
W
K
P
G
T
A
V
D
V
A
V
N
T
Y
G
V
D
L
G
E
G
M
F
G
E
D
N
V
Q
T
H
F
T
I
G
D
E
V
I
A
T
A
D
D
N
T
K
I
L
T
V
R
V
N
G
E
V
V
K
S
M
P
T
S
M
G
K
D
S
T
P
T
A
N
G
I
Y
I
V
G
S
R
Y
K
H
I
I
M
D
S
S
T
Y
G
V
P
V
N
S
P
N
G
Y
R
T
D
V
D
W
A
T
Q
I
S
Y
S
G
V
F
V
H
S
A
P
W
S
V
G
A
Q
G
H
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
W
F
Y
D
H
V
K
R
G
D
I
V
E
V
V
N
T
V
G
G
T
L
P
G
I
D
G
L
G
D
W
N
I
P
W
D
Q
W
R
A
G
N
A
K
-
29
PsiBlast_CBE
60.52
43%
-81
- C5 -
4JMX
1
LDT1_MYCTU
A:
[35-219]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
R
A
V
E
R
S
I
R
I
S
T
P
H
N
T
T
G
H
F
E
W
V
A
S
N
V
V
R
W
V
P
H
R
Y
W
P
P
H
T
R
V
S
V
G
V
Q
----
E
L
T
E
G
----------
F
E
T
G
D
A
L
I
G
V
A
S
I
S
A
H
T
F
T
V
S
R
N
G
E
V
L
R
T
M
P
A
S
L
G
K
P
S
R
P
T
P
I
G
S
F
H
A
M
S
K
E
R
T
V
V
M
D
S
R
T
I
G
I
P
L
N
S
S
D
G
Y
L
L
T
A
H
Y
A
V
R
V
T
W
S
G
V
Y
V
H
S
A
P
W
S
V
N
S
Q
G
Y
A
N
V
S
H
G
C
I
N
L
S
P
D
N
A
A
W
Y
F
D
A
V
T
V
G
D
P
I
E
V
V
------------------------------