@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2671: (2016-05-12 )
MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT
Atome Classification :
(20 SA)
.........10........20--........30..----.-.....40........50-.-..-.....60.-.......70........80.......-------.90...-.....100.......----110.......120.....-..-130..---.--.---...140.......-----150--..--...-...----160-----..----.....170.......180.-..-....190.......200........210.......220.-..-.-..--.230----.......240........250......-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MPDSGQLGAA
D
T
P
L
R
L
L
S
S
V
H
--YLTDGELPQLYD----Y-PDDG
T
W
L
R
A
N
F
ISSLDG-G-AT-VDGTSGAM-AGPG
D
R
F
V
F
N
L
L
R
E
L
A
D
V
I
V
V
G
V
G
T
V
-------
R
I
EGYS-G
V
R
M
G
V
V
Q
R
Q
H
R
QAR----GQSEV
P
Q
L
A
I
V
TRSGRLD-RD-
M
A
V
F
T
---R--T---EMA
P
L
V
L
T
T
TAVA-----
D
D
---
T
R
--
Q
R
L
-
A
G
L
----
A
E
V
-----
I
A----CSGDDPG
T
V
D
E
A
V
L
V
S
Q
L
A
-
A
R
-
G
L
R
R
I
L
TEGG
P
T
L
L
G
T
-
F
V
E
R
D
V
L
D
E
L
C
L
T
I
A
P
Y
V
V
G
G
L
-
A
R
-
R
-IV--TG
P
G
----
Q
V
L
T
R
M
R
C
A
-
H
V
LTDDS
G
Y
L
Y
T
R
Y
VKT-
1
PsiBlast_PDB
98.26
100%
-133
- C1 -
4XRB
2
?
A:
[10-258]
---------
A
D
T
P
L
R
L
L
S
S
V
H
--
Y
L
T
D
G
E
L
P
Q
L
Y
D
----
Y
-
P
D
D
G
T
W
L
R
A
N
F
I
S
S
L
D
G
-
G
-
A
T
-
V
D
G
T
S
G
A
M
-
A
G
P
G
D
R
F
V
F
N
L
L
R
E
L
A
D
V
I
V
V
G
V
G
T
V
-------
R
---
Y
S
-
G
V
R
M
G
V
V
Q
R
Q
H
R
Q
A
R
----
G
Q
S
E
V
P
Q
L
A
I
V
T
R
S
G
R
L
D
-
R
D
-
M
A
V
F
T
---
R
--
T
---
E
M
A
P
L
V
L
T
T
T
A
V
A
-----
D
D
---
T
R
--
Q
R
L
-
A
G
L
----
A
E
V
-----
I
A
----
C
S
G
D
D
P
G
T
V
D
E
A
V
L
V
S
Q
L
A
-
A
R
-
G
L
R
R
I
L
T
E
G
G
P
T
L
L
G
T
-
F
V
E
R
D
V
L
D
E
L
C
L
T
I
A
P
Y
V
V
G
G
L
-
A
R
-
R
-
I
V
--
T
G
P
G
----
Q
V
L
T
R
M
R
C
A
-
H
V
L
T
D
D
S
G
Y
L
Y
T
R
Y
V
K
T
-
5
PsiBlast_PDB
97.69
100%
-123
- C1 -
4XT8
7
?
A:
[13-258]
------------
P
L
R
L
L
S
S
V
H
--
Y
L
T
D
G
E
L
P
Q
L
Y
D
----
Y
-
P
D
D
G
T
W
L
R
A
N
F
I
S
S
L
D
G
-
G
-
A
T
-
V
D
G
T
S
G
A
M
-
A
G
P
G
D
R
F
V
F
N
L
L
R
E
L
A
D
V
I
V
V
G
V
G
T
V
-------
R
I
E
G
Y
S
-
G
V
R
M
G
V
V
Q
R
Q
H
R
Q
A
R
----
G
Q
S
E
V
P
Q
L
A
I
V
T
R
S
G
R
L
D
-
R
D
-
M
A
V
F
T
---
R
--
T
---
E
M
A
P
L
V
L
T
T
T
A
V
A
-----
D
D
---
T
R
--
Q
R
L
-
A
G
L
----
A
E
V
-----
I
A
----
C
S
G
D
D
P
G
T
V
D
E
A
V
L
V
S
Q
L
A
-
A
R
-
G
L
R
R
I
L
T
E
G
G
P
T
L
L
G
T
-
F
V
E
R
D
V
L
D
E
L
C
L
T
I
A
P
Y
V
V
G
G
L
-
A
R
-
R
-
I
V
--
T
G
P
G
----
Q
V
L
T
R
M
R
C
A
-
H
V
L
T
D
D
S
G
Y
L
Y
T
R
Y
V
K
T
-
4
PsiBlast_PDB
96.70
100%
-120
- C1 -
4XT7
4
?
A:
[13-258]
------------
P
L
R
L
L
S
S
V
H
--
Y
L
T
D
G
E
L
P
Q
L
Y
D
----
Y
-
P
D
D
G
T
W
L
R
A
N
F
I
S
S
L
D
G
-
G
-
A
T
-
V
D
G
T
S
G
A
M
-
A
G
P
G
D
R
F
V
F
N
L
L
R
E
L
A
D
V
I
V
V
G
V
G
T
V
-------
R
I
E
G
Y
S
-
G
V
R
M
G
V
V
Q
R
Q
H
R
Q
A
R
----
G
Q
S
E
V
P
Q
L
A
I
V
T
R
S
G
R
L
D
-
R
D
-
M
A
V
F
T
---
R
--
T
---
E
M
A
P
L
V
L
T
T
T
A
V
A
-----
D
D
---
T
R
--
Q
R
L
-
A
G
L
----
A
E
V
-----
I
A
----
C
S
G
D
D
P
G
T
V
D
E
A
V
L
V
S
Q
L
A
-
A
R
-
G
L
R
R
I
L
T
E
G
G
P
T
L
L
G
T
-
F
V
E
R
D
V
L
D
E
L
C
L
T
I
A
P
Y
V
V
G
G
L
-
A
R
-
R
-
I
V
--
T
G
P
G
----
Q
V
L
T
R
M
R
C
A
-
H
V
L
T
D
D
S
G
Y
L
Y
T
R
Y
V
K
T
-
2
PsiBlast_PDB
96.63
100%
-126
- C1 -
4XT4
4
?
A:
[13-258]
------------
P
L
R
L
L
S
S
V
H
--
Y
L
T
D
G
E
L
P
Q
L
Y
D
----
Y
-
P
D
D
G
T
W
L
R
A
N
F
I
S
S
L
D
G
-
G
-
A
T
-
V
D
G
T
S
G
A
M
-
A
G
P
G
D
R
F
V
F
N
L
L
R
E
L
A
D
V
I
V
V
G
V
G
T
V
-------
R
I
E
G
Y
S
-
G
V
R
M
G
V
V
Q
R
Q
H
R
Q
A
R
----
G
Q
S
E
V
P
Q
L
A
I
V
T
R
S
G
R
L
D
-
R
D
-
M
A
V
F
T
---
R
--
T
---
E
M
A
P
L
V
L
T
T
T
A
V
A
-----
D
D
---
T
R
--
Q
R
L
-
A
G
L
----
A
E
V
-----
I
A
----
C
S
G
D
D
P
G
T
V
D
E
A
V
L
V
S
Q
L
A
-
A
R
-
G
L
R
R
I
L
T
E
G
G
P
T
L
L
G
T
-
F
V
E
R
D
V
L
D
E
L
C
L
T
I
A
P
Y
V
V
G
G
L
-
A
R
-
R
-
I
V
--
T
G
P
G
----
Q
V
L
T
R
M
R
C
A
-
H
V
L
T
D
D
S
G
Y
L
Y
T
R
Y
V
K
T
-
3
PsiBlast_PDB
96.55
100%
-121
- C1 -
4XT5
1
?
A:
[13-258]
------------
P
L
R
L
L
S
S
V
H
--
Y
L
T
D
G
E
L
P
Q
L
Y
D
----
Y
-
P
D
D
G
T
W
L
R
A
N
F
I
S
S
L
D
G
-
G
-
A
T
-
V
D
G
T
S
G
A
M
-
A
G
P
G
D
R
F
V
F
N
L
L
R
E
L
A
D
V
I
V
V
G
V
G
T
V
-------
R
I
E
G
Y
S
-
G
V
R
M
G
V
V
Q
R
Q
H
R
Q
A
R
----
G
Q
S
E
V
P
Q
L
A
I
V
T
R
S
G
R
L
D
-
R
D
-
M
A
V
F
T
---
R
--
T
---
E
M
A
P
L
V
L
T
T
T
A
V
A
-----
D
D
---
T
R
--
Q
R
L
-
A
G
L
----
A
E
V
-----
I
A
----
C
S
G
D
D
P
G
T
V
D
E
A
V
L
V
S
Q
L
A
-
A
R
-
G
L
R
R
I
L
T
E
G
G
P
T
L
L
G
T
-
F
V
E
R
D
V
L
D
E
L
C
L
T
I
A
P
Y
V
V
G
G
L
-
A
R
-
R
-
I
V
--
T
G
P
G
----
Q
V
L
T
R
M
R
C
A
-
H
V
L
T
D
D
S
G
Y
L
Y
T
R
Y
V
K
T
-
24
HHSearch
66.99
30%
-106
* C1 *
2P4G
16
?
A:
[31-260]
------------------------------------------
I
N
E
P
E
C
R
A
I
A
I
T
S
I
N
G
-
S
-
A
T
-
L
S
G
V
S
G
P
M
-
G
D
Q
T
D
A
D
L
L
I
Q
L
R
G
W
A
D
A
I
V
V
G
A
E
T
A
-------
R
K
E
N
Y
G
-
P
V
V
L
P
H
G
I
K
N
Q
R
Q
K
L
----
G
R
C
G
L
P
K
L
T
L
L
S
K
S
L
Y
F
D
-
F
S
-
S
E
L
F
S
---
P
--
D
LPS
E
L
S
P
L
V
I
T
Q
Q
P
A
N
NS
E
Q
W
D
Q
---
R
L
--
Q
K
L
I
D
V
G
----
V
E
V
-----
I
V
----
A
P
T
S
---
T
N
P
L
K
I
A
F
D
A
L
H
-
A
R
-
R
L
K
K
I
S
I
E
G
G
P
S
V
Y
R
Q
-
A
L
S
L
G
I
V
D
R
L
H
L
T
I
A
P
N
I
I
C
P
V
-
E
S
-
P
-
L
F
--
G
K
I
S
D
D
--
S
F
T
T
R
L
V
L
E
-
M
L
S
S
S
P
N
G
L
I
F
S
R
Y
K
V
--
11
PsiBlast_PDB
64.08
24%
-121
- C1 -
2AZN
4
RIB7_METJA
A:
[5-178]
----------------------------------------------
Y
I
I
S
N
V
G
M
T
L
D
G
-
K
-
L
A
-
T
I
N
N
D
S
R
I
-
S
C
E
E
D
L
I
R
V
H
K
I
R
A
N
V
D
G
I
M
V
G
I
G
T
V
-------
L
---
K
D
-
D
P
R
L
T
V
----
H
K
I
K
S
----
D
R
N
--
P
V
R
I
V
V
D
S
K
L
R
V
P
-
L
N
-
A
R
V
L
N
---
K
------
D
A
K
T
I
I
A
T
T
E
D
T
N
-----
E
E
---
K
E
--
K
K
I
-
K
I
L
E
D
M
G
V
E
V
-----
V
K
----
C
G
---
R
G
K
V
D
L
K
K
L
M
D
I
L
Y
-
D
K
-
G
I
K
S
I
L
L
E
G
G
G
T
L
N
W
G
-
M
F
K
E
G
L
V
D
E
V
S
V
Y
I
A
P
K
I
F
G
G
-----------------------------------------------
6
PsiBlast_PDB
62.43
28%
-103
- C1 -
2P4G
16
?
A:
[37-258]
------------------------------------------------
R
A
I
A
I
T
S
I
N
G
-
S
-
A
T
-
L
S
G
V
S
G
P
M
-
G
D
Q
T
D
A
D
L
L
I
Q
L
R
G
W
A
D
A
I
V
V
G
A
E
T
A
-------
R
K
E
N
Y
G
-
P
V
V
L
P
H
G
I
K
N
Q
R
Q
K
L
----
G
R
C
G
L
P
K
L
T
L
L
S
K
S
L
Y
F
D
-
F
S
-
S
E
L
F
S
PDL
P
--
S
---
E
L
S
P
L
V
I
T
Q
Q
P
A
N
-----
N
S
---
E
Q
W
D
Q
R
L
-
Q
K
L
----
I
D
V
G
V
E
V
I
V
A
----
P
T
S
T
N
P
----
L
K
I
A
F
D
A
L
H
-
A
R
-
R
L
K
K
I
S
I
E
G
G
P
S
V
Y
R
Q
-
A
L
S
L
G
I
V
D
R
L
H
L
T
I
A
P
N
I
I
C
P
V
-
E
S
-
P
-
L
F
GK
I
S
D
D
----
S
F
T
T
R
L
V
L
E
-
M
L
S
S
S
P
N
G
L
I
F
S
R
Y
----
26
HHSearch
61.82
22%
-100
- C1 -
2AZN
4
RIB7_METJA
A:
[2-217]
-------------------------------------------
K
K
P
Y
I
I
S
N
V
G
M
T
L
D
G
-
K
-
L
A
T
I
N
N
D
-
S
R
I
-
S
C
E
E
D
L
I
R
V
H
K
I
R
A
N
V
D
G
I
M
V
G
I
G
T
V
-------
L
K
D
D
P
R
-
L
T
V
--------
H
K
-
I
----
K
S
D
R
N
P
V
R
I
V
V
D
S
K
L
R
V
P
-
L
N
-
A
R
V
L
N
---
K
------
D
A
K
T
I
I
A
T
T
E
D
T
N
-----
E
E
K
E
K
K
I
--
K
I
L
E
D
M
G
----
V
E
V
-----
V
K
----
C
G
R
G
---
K
V
D
L
K
K
L
M
D
I
L
Y
-
D
K
-
G
I
K
S
I
L
L
E
G
G
G
T
L
N
W
G
-
M
F
K
E
G
L
V
D
E
V
S
V
Y
I
A
P
K
I
F
G
G
K
-
E
A
-
P
T
Y
V
--
D
G
E
G
FKTV
D
E
C
V
K
L
E
L
K
-
N
F
Y
R
L
G
E
G
I
V
-
L
E
F
K
V
--
45
Fugue
61.28
24%
-94
- C1 -
2P4G
16
?
A:
[16-263]
-----------
V
T
T
E
Q
I
V
Y
G
A
-----------
L
P
L
----
T
-
T
I
N
E
P
E
C
R
A
I
A
I
T
S
I
N
G
-
S
-
A
T
-
L
S
G
V
S
G
-
P
M
G
D
Q
T
D
A
D
L
L
I
Q
L
R
G
W
A
D
A
I
V
V
G
A
E
T
A
-------
R
K
E
N
Y
G
-
P
V
V
L
P
H
G
I
K
N
Q
R
Q
K
L
----
G
R
C
G
L
P
K
L
T
L
L
S
K
S
L
Y
F
D
-
F
S
-
S
E
L
F
S
---
P
DL
P
---
S
E
L
S
P
L
V
I
T
Q
Q
P
A
-----
N
N
---
S
E
--
Q
W
D
-
Q
R
L
----
Q
K
L
-----
I
D
V
G
V
E
V
I
V
A
P
T
S
T
N
P
L
K
I
A
F
D
A
L
H
-
A
R
-
R
L
K
K
I
S
I
E
G
G
P
S
V
Y
R
Q
-
A
L
S
L
G
I
V
D
R
L
H
L
T
I
A
P
N
I
I
C
P
V
-
E
S
-
P
-
L
F
--
G
K
I
S
D
D
--
S
F
T
T
R
L
V
L
E
M
L
S
S
S
P
N
G
L
I
F
S
R
Y
K
V
I
R
D
25
HHSearch
58.45
19%
-90
- C1 -
2B3Z
-
RIBD_BACSU
A:
[114-370]
-
P
N
P
L
V
A
G
R
G
I
S
M
M
K
E
A
G
I
E
V
R
E
G
I
L
A
D
Q
A
E
R
L
N
E
K
F
L
H
F
M
R
T
G
L
P
Y
V
T
L
K
A
A
A
S
L
D
G
-
K
-
I
A
T
S
T
G
D
S
K
W
I
-
T
S
E
A
A
R
Q
D
A
Q
Q
Y
R
K
T
H
Q
S
I
L
V
G
V
G
T
V
-------
K
A
D
N
P
S
-
L
T
C
--------
R
L
P
-----
N
V
T
K
Q
P
V
R
V
I
L
D
T
V
L
S
I
P
-
E
D
-
A
K
V
I
C
---
D
--
Q
---
I
A
P
T
W
I
F
T
T
A
R
A
D
-----
E
E
---
K
K
--
K
R
L
S
A
F
G
----
V
N
I
-----
F
T
----
L
E
T
E
---
R
I
Q
I
P
D
V
L
K
I
L
A
-
E
E
-
G
I
M
S
V
Y
V
E
G
G
S
A
V
H
G
S
-
F
V
K
E
G
C
F
Q
E
I
I
F
Y
F
A
P
K
L
I
G
G
T
-
H
A
P
S
-
L
I
--
S
G
E
G
FQSM
K
D
V
P
L
L
Q
F
T
-
D
I
T
Q
I
G
R
D
-
I
K
L
T
A
K
P
--
9
PsiBlast_PDB
58.31
27%
-97
- C1 -
3EX8
-
RIBD_BACSU
A:
[166-342]
-----------------------------------------------------
A
S
L
D
G
-
K
I
A
T
-
S
T
G
D
S
K
W
I
-
T
S
E
A
A
R
Q
D
A
Q
Q
Y
R
K
T
H
Q
S
I
L
V
G
V
G
T
V
-------
K
A
D
N
P
S
L
T
C
R
L
P
N
V
T
K
Q
--------------
P
V
R
V
I
L
D
T
V
L
S
I
P
-
E
D
-
A
K
V
I
C
------
D
---
Q
I
A
P
T
W
I
F
T
T
A
R
A
-----
D
E
E
--
K
K
--
K
R
L
-
S
A
F
----
G
V
N
-----
I
F
----
T
L
E
T
E
R
I
Q
I
P
D
V
L
K
I
--
L
A
-
E
E
-
G
I
M
S
V
Y
V
E
G
G
S
A
V
H
G
S
-
F
V
K
E
G
C
F
Q
E
I
I
F
Y
F
A
P
K
L
I
G
G
T
H
A
P
-
S
-
L
I
--
S
G
E
G
--------------------------------
7
PsiBlast_PDB
58.19
27%
-99
- C1 -
2B3Z
-
RIBD_BACSU
A:
[166-342]
-----------------------------------------------------
A
S
L
D
G
-
K
I
A
T
-
S
T
G
D
S
K
W
I
-
T
S
E
A
A
R
Q
D
A
Q
Q
Y
R
K
T
H
Q
S
I
L
V
G
V
G
T
V
-------
K
A
D
N
P
S
L
T
C
R
L
P
N
V
T
K
Q
--------------
P
V
R
V
I
L
D
T
V
L
S
I
P
-
E
D
-
A
K
V
I
C
------
D
---
Q
I
A
P
T
W
I
F
T
T
A
R
A
-----
D
E
E
--
K
K
--
K
R
L
-
S
A
F
----
G
V
N
-----
I
F
----
T
L
E
T
E
R
I
Q
I
P
D
V
L
K
I
--
L
A
-
E
E
-
G
I
M
S
V
Y
V
E
G
G
S
A
V
H
G
S
-
F
V
K
E
G
C
F
Q
E
I
I
F
Y
F
A
P
K
L
I
G
G
T
H
A
P
-
S
-
L
I
--
S
G
E
G
--------------------------------
29
HHSearch
58.11
20%
-100
- C1 -
3ZPG
6
?
A:
[128-378]
-
P
N
P
L
V
A
G
K
G
V
Q
I
L
K
N
A
G
I
E
V
E
I
G
I
C
E
D
L
A
A
K
L
N
Q
G
F
L
K
A
M
S
T
G
M
P
Y
V
R
L
K
V
A
S
S
L
D
G
-
R
-
T
A
M
A
S
G
E
S
--
I
-
T
G
S
A
A
R
Q
D
V
Q
H
W
R
A
I
S
G
A
V
I
T
G
I
D
T
V
-------
I
A
D
D
C
Q
-
L
N
V
--------
R
S
L
H
NIDI
E
T
V
A
Q
P
K
R
V
I
L
D
R
R
G
R
L
P
-
L
T
-
A
K
I
L
E
---
N
-------
P
E
T
V
M
V
M
G
P
Y
R
---------------
Q
E
L
A
D
L
G
----
V
I
Q
-----
L
E
-----------
I
Q
P
L
K
T
L
L
Q
T
L
S
K
Q
Y
-
Q
I
Y
D
V
L
I
E
A
G
A
T
L
S
S
A
-
F
L
Q
E
G
L
I
D
E
M
I
S
Y
V
A
P
T
L
L
G
Q
S
-
A
R
-
A
-
M
F
--
N
A
D
F
E
Y
M-
A
Q
Q
L
R
F
K
L
L
-
D
V
I
Q
L
D
-
Q
D
I
R
L
R
L
I
P
T
-
10
PsiBlast_PDB
57.95
27%
-102
- C1 -
4G3M
1
RIBD_BACSU
A:
[166-342]
-----------------------------------------------------
A
S
L
D
G
-
K
I
A
T
-
S
T
G
D
S
K
W
I
-
T
S
E
A
A
R
Q
D
A
Q
Q
Y
R
K
T
H
Q
S
I
L
V
G
V
G
T
V
-------
K
A
D
N
P
S
L
T
C
R
L
P
N
V
T
K
Q
--------------
P
V
R
V
I
L
D
T
V
L
S
I
P
-
E
D
-
A
K
V
I
C
------
D
---
Q
I
A
P
T
W
I
F
T
T
A
R
A
-----
D
E
E
--
K
K
--
K
R
L
-
S
A
F
----
G
V
N
-----
I
F
----
T
L
E
T
E
R
I
Q
I
P
D
V
L
K
I
--
L
A
-
E
E
-
G
I
M
S
V
Y
V
E
G
G
S
A
V
H
G
S
-
F
V
K
E
G
C
F
Q
E
I
I
F
Y
F
A
P
K
L
I
G
G
T
H
A
P
-
S
-
L
I
--
S
G
E
G
--------------------------------
30
HHSearch
56.36
20%
-91
- C1 -
2HXV
8
?
A:
[122-356]
-------
G
N
G
V
E
K
F
R
N
H
G
I
E
V
I
E
G
V
L
E
E
E
V
K
K
L
C
E
F
F
I
T
Y
V
T
K
K
R
P
F
V
A
L
K
Y
A
S
T
L
D
G
-
K
-
I
A
D
H
R
G
D
S
K
W
I
-
T
D
K
-
L
R
F
K
V
H
E
M
R
N
I
Y
S
A
V
L
V
G
A
G
T
V
-------
L
K
D
N
P
Q
-
L
T
C
--------
R
L
K
------
E
G
R
N
P
V
R
V
I
L
D
R
K
G
V
L
S
-
G
K
V
F
R
V
F
E
---
E
------
N
A
R
V
I
V
F
T
E
S
E
E
A
-----
E
Y
-----------
P
P
H
----
V
E
K
-----
A
L
-----
S
-----
D
C
S
V
E
S
I
L
R
N
L
Y
-
E
R
-
D
I
D
S
V
L
V
E
G
G
S
K
V
F
S
E
-
F
L
D
H
--
A
D
V
V
F
G
F
Y
S
T
K
I
F
G
K
G
--
L
-
D
-
V
F
--
S
G
Y
L
S
D
V-
S
V
P
P
K
F
K
V
V
-
N
V
E
F
S
-
D
S
E
F
L
V
E
M
R
P
--
8
PsiBlast_PDB
55.80
27%
-98
- C1 -
2D5N
-
RIBD_BACSU
A:
[166-342]
-----------------------------------------------------
A
S
L
D
G
-
K
I
A
T
-
S
T
G
D
S
K
W
I
-
T
S
E
A
A
R
Q
D
A
Q
Q
Y
R
K
T
H
Q
S
I
L
V
G
V
G
T
V
-------
K
A
D
N
P
S
L
T
C
R
L
P
N
V
T
K
Q
--------------
P
V
R
V
I
L
D
T
V
L
S
I
P
-
E
D
-
A
K
V
I
C
------
D
---
Q
I
A
P
T
W
I
F
T
T
A
R
A
-----
D
E
E
--
K
K
--
K
R
L
-
S
A
F
----
G
V
N
-----
I
F
----
T
L
E
T
E
R
I
Q
I
P
D
V
L
K
I
--
L
A
-
E
E
-
G
I
M
S
V
Y
V
E
G
G
S
A
V
H
G
S
-
F
V
K
E
G
C
F
Q
E
I
I
F
Y
F
A
P
K
L
I
G
G
T
H
A
P
-
S
-
L
I
--
S
G
E
G
--------------------------------
17
PsiBlast_PDB
54.53
24%
-112
- C1 -
3ZPC
2
?
A:
[173-348]
----------------------------------------------
Y
V
R
L
K
V
A
S
S
L
D
G
R
T
-
A
M
-
A
S
G
E
S
K
W
I
-
T
G
S
A
A
R
Q
D
V
Q
H
W
R
A
I
S
G
A
V
I
T
G
I
D
T
V
I
A
DDCQL
N
V
R
S
L
H
-
N
I
D
I
E
T
V
A
Q
---------------
P
K
R
V
I
L
D
R
R
G
R
L
P
-
L
T
-
A
K
I
L
E
---
N
--
P
---
E
-------
T
V
M
V
M
-----
G
P
---
Y
R
--
Q
E
L
-
A
D
L
----
G
-
V
-----
I
Q
----
L
E
I
Q
P
L
K
T
-----
L
L
Q
T
L
S
-
K
Q
Y
Q
I
Y
D
V
L
I
E
A
G
A
T
L
S
S
A
-
F
L
Q
E
G
L
I
D
E
M
I
S
Y
V
A
P
T
L
L
G
Q
S
-
A
R
-
A
-
M
F
--
N
A
----------------------------------
18
PsiBlast_PDB
51.67
24%
-111
- C1 -
3ZPG
6
?
A:
[173-348]
----------------------------------------------
Y
V
R
L
K
V
A
S
S
L
D
G
R
T
-
A
M
-
A
S
G
E
S
--
I
-
T
G
S
A
A
R
Q
D
V
Q
H
W
R
A
I
S
G
A
V
I
T
G
I
D
T
V
I
A
DDCQL
N
V
R
S
L
H
-
N
I
D
I
E
T
V
A
Q
---------------
P
K
R
V
I
L
D
R
R
G
R
L
P
-
L
T
-
A
K
I
L
E
---
N
--
P
---
E
-------
T
V
M
V
M
-----
G
P
---
Y
R
--
Q
E
L
-
A
D
L
----
G
-
V
-----
I
Q
----
L
E
I
Q
P
L
K
T
-----
L
L
Q
T
L
S
-
K
Q
Y
Q
I
Y
D
V
L
I
E
A
G
A
T
L
S
S
A
-
F
L
Q
E
G
L
I
D
E
M
I
S
Y
V
A
P
T
L
L
G
Q
S
-
A
R
-
A
-
M
F
--
N
A
----------------------------------
46
Fugue
50.88
16%
-90
- C1 -
4HA7
-
RIB7_YEAST
A:
[8-242]
----------
E
D
L
P
Q
F
L
Q
--
N
--
Y
L
P
N
A
G
Q
T
E
N
T
I
----
V
-
P
----
F
V
T
L
T
Y
A
Q
S
L
D
A
-
R
-
V
S
----------
R
G
P
E
T
K
T
M
T
H
Y
L
R
H
H
H
D
G
I
L
V
G
S
G
T
V
-------
L
A
D
-------------
N
P
G
L
N
C
----
K
W
G
N
S
P
R
P
I
I
I
D
T
K
Q
K
W
R
F
D
G
-
S
K
M
Q
E
---
L
--
F
---
I
K
R
Q
G
K
P
P
I
V
V
V
T
-----
S
E
---
P
I
--
I
K
E
-
Q
H
V
----
D
Y
A
-----
I
C
----
P
I
N
D
T
T
K
L
V
D
W
K
K
L
F
E
I
L
K
-
E
E
F
N
I
R
S
V
M
V
E
G
G
A
N
V
I
N
Q
L
L
L
R
S
D
I
V
N
S
L
I
I
T
I
G
S
T
F
L
G
S
S
-
G
T
-
E
-
V
S
--
P
P
Q
T
-------
V
N
L
K
D
M
-
S
W
W
K
G
I
T
D
V
V
L
C
A
R
L
A
--