@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2744c: (2016-05-13 )
MANPFVKAWKYLMALFSSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQVIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQATAAGDAAKATEYNNAAEAFAAQLVTAEQSVEDLKTLHDQALSAAAQAKKAVERNAMVLQQKIAERTKLLSQLEQAKMQEQVSASLRSMSELAAPGNTPSLDEVRDKIERRYANAIGSAELAESSVQGRMLEVEQAGIQMAGHSRLEQIRASMRGEALPAGGTTATPRPATETSGGAIAEQPYGQ
Atome Classification :
(20 SA)
---------------------------------------.........10........20........30--........40.......--.50.-------......----.60........----------70--....------.----------..-.80...---......-90........---100.......110..-.....120-.......130.......140-.......150-----....--....160.......170.......180....--...190---........---.200-------.......210.----....------..220---.......230.....----------..240.......-----------250.......260.......270
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------MAN
P
F
V
K
A
W
K
Y
L
M
A
L
F
S
S
K
I
DEHAD
P
K
V
Q
I
Q
--
Q
A
I
E
E
A
Q
R
T
H
Q
A
L
T
Q
Q
A
--
A
Q
V
I-------G
N
Q
R
Q
L
----
E
M
R
L
N
R
Q
L
A
D
I
----------
E
K
--
L
Q
V
N
------
V
----------
R
Q
-
A
L
-
T
LA---DQATAA-GDAAKATEYN---
N
A
A
E
A
F
A
A
Q
L
V
T
A
E
Q
-
S
V
E
D
L
K
T
L
-
H
D
Q
A
L
S
A
A
A
Q
A
K
K
A
V
E
R
N
A
M
-
V
L
Q
Q
K
I
A
E
R
------
T
K
L
L
--
S
Q
L
E
Q
A
K
M
Q
E
Q
V
S
A
S
L
R
S
M
S
E
LAAPGNTP
S
L
--
D
E
V
R
-----
D
K
I
E
R
R
Y
A
---
N
AIG-------
S
A
E
L
A
E
S
S
VQG----
R
M
L
E
------
V
E
QAG---IQMA
G
H
S
R
L
E
Q
I
R
A
S
----------MRGEALPAGGTT-----------ATPRPATETSGGAIAEQPYGQ--
38
Fugue
72.95
15%
-20
* C1 *
3AJW
1
FLIJ_SALTY
A:
[6-141]
--------------------------------------------------------------------
Q
H
--
G
A
L
E
T
L
K
D
L
A
E
K
E
V
D
D
A
--
A
R
L
L
-------
G
E
M
R
R
G
----
C
Q
Q
A
E
E
Q
L
K
M
L
----------
I
D
--
Y
Q
N
E
------
Y
----------
R
S
-
N
L
--------
N
M
G
N
G
-
I
A
S
N
R
W
I
N
Y
Q
---
Q
F
I
Q
T
L
E
K
A
I
E
Q
H
R
L
-
Q
L
T
Q
W
T
Q
K
-
V
D
L
A
L
K
S
W
R
E
K
K
Q
R
L
Q
A
W
Q
T
-
L
Q
D
R
Q
T
A
A
A
------
L
L
A
E
--
N
R
M
D
Q
K
K
M
D
E
F
A
------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
72.46
18%
14
- C1 -
1JR7
1
CSID_ECOLI
A:
[1-311]
--------------------------------GQDYSG
F
T
L
T
P
S
A
Q
S
P
R
L
L
E
L
T
F
T
E
Q
T
T
K
Q
F
L
E
Q
V
A
E
W
P
V
Q
A
L
E
Y
K
S
F
L
R
F
R
V
A
K
I
L
--
D
D
L
C
-------
A
N
Q
--
L
----
Q
P
L
L
L
K
T
L
L
N
R
----------
A
E
G
A
L
L
I
N
A
V
GVDD
V
----------
K
Q
-
A
D
-
E
M
V
---
K
L
A
T
A
V
-
A
H
L
I
G
R
S
N
F
D
---
A
M
S
G
Q
Y
Y
A
R
F
V
V
K
N
V
-
Y
L
R
--
Q
P
H
-
R
V
M
E
L
H
N
D
G
T
Y
V
E
--
E
I
T
D
Y
-
V
L
M
M
K
I
D
E
Q
NMQGG
N
S
L
L
L
H
L
D
D
W
E
H
L
D
N
Y
F
R
H
P
L
A
R
R
P
M
R
F
A
A
P
P
S
K
N
V
S
K
--
D
V
F
H
P
V
F
D
V
D
Q
Q
G
R
P
V
M
---
R
Y
I
D
-------
Q
F
V
Q
P
K
D
F
E
E
G
----
V
W
L
S
------
E
L
S
D
A
---
I
E
T
S
K
G
I
L
S
V
P
V
P
V
G
K
F
L
L
I
NNLF
W
L
H
G
R
D
R
F
T
P
H
P
D
-----------
L
R
R
E
L
M
R
Q
R
G
Y
F
A
Y
A
S
N
H
Y
Q
T
H
Q
14
HHSearch
69.72
15%
-16
- C2 -
4WHE
1
PSPA_ECOLI
A:
[3-142]
------------------------------------------
I
F
S
R
F
A
D
I
V
N
A
N
I
N
A
L
L
E
---
D
P
Q
K
L
V
R
--
L
M
I
Q
E
M
E
D
T
L
V
E
V
R
S
T
S
--
A
R
A
L
-------
A
E
K
K
Q
L
----
T
R
R
I
E
Q
A
S
A
R
E
----------
V
E
--
W
Q
E
K
------
A
----------
E
L
-
A
L
-
L
K
E
---
R
E
D
L
A
R
-
A
A
L
I
E
K
Q
K
L
T
---
D
L
I
K
S
L
E
H
E
V
T
L
V
D
D
-
T
L
A
R
M
K
---------------
K
E
I
G
E
L
E
N
-
K
L
S
E
T
R
A
R
Q
------
Q
A
L
M
--
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
64.43
24%
16
- C1 -
4OYD
-
?
B:
[1-117]
--------------------------------------------------------------
A
D
P
K
K
V
L
D
--
K
A
K
D
Q
A
E
N
R
V
R
E
L
K
Q
K
L
--
E
E
L
Y
-------
K
E
A
R
K
L
DLT
Q
E
M
R
R
K
L
E
L
R
Y
I
----------
A
A
--
M
L
M
A
------
I
----------
G
D
-
I
Y
-
N
A
I
---
R
Q
A
K
Q
E
-
A
D
K
L
K
K
--------------
A
G
L
V
N
S
Q
Q
-
L
D
E
L
K
R
R
L
-
E
E
L
K
E
E
A
S
R
K
A
R
D
Y
G
R
E
F
Q
L
-
K
L
E
Y
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
61.12
13%
-1
- C1 -
3M1G
5
?
A:
[29-361]
N
Y
I
D
D
R
I
V
ADVPAGSE
P
I
A
Q
EDG
T
F
H
W
P
V
E
A
GR
Y
R
L
V
A
A
R
A
C
P
W
A
H
R
T
V
I
T
R
R
L
L
G
------
L
E
N
V
I
S
L
G
--
L
T
G
P
T
H
D
I
T
V
P
A
L
V
E
E
S
SK
K
V
V
T
-------
N
D
Y
P
S
I
----
T
I
D
F
N
L
E
W
K
Q
F
HREGAPNLYP
A
E
--
L
R
E
E
M
-----
A
----------
P
V
M
K
R
-
I
F
T
E
VN
N
G
V
Y
R
T
-
G
F
A
G
S
Q
E
A
H
N
---
E
A
Y
K
R
L
W
V
A
L
D
W
L
E
D
-
R
L
S
T
R
R
Y
L
M
G
D
H
I
T
E
A
D
I
R
L
Y
P
T
L
V
R
F
D
A
-
V
Y
H
G
H
F
K
C
G
------
R
N
K
I
--
T
E
M
------
P
N
L
W
G
Y
L
R
D
L
F
Q
T
P
G
F
G
D
T
T
D
F
--
T
E
I
K
-----
Q
H
Y
Y
I
T
H
A
---
E
I
N
P
-------
T
R
I
V
P
V
G
P
D
L
S
----
G
F
A
T
------
P
H
G
-----------------
R
E
K
----------
L
G
G
S
P
F
A
E
G
V
T
L
---------------
P
G
P
I
P
A
G
E
E
V
K
N
P
E
P
F
Q
--
16
HHSearch
57.84
13%
9
- C2 -
5FD9
-
SNF7_YEAST
A:
[19-95]
------------------------------------------------------------------------------------
P
T
K
A
I
--
V
R
L
R
-------
E
H
I
N
L
L
----
S
K
K
Q
S
H
L
R
T
Q
I
----------
T
N
--
Q
E
N
E
------
A
----------
R
I
-
F
L
-
T
K
G
---
N
K
V
M
A
K
-
N
A
L
K
K
K
K
T
I
E
---
Q
L
L
S
K
V
E
G
T
M
E
S
M
E
Q
-
Q
L
F
S
I
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
57.71
10%
-14
- C1 -
4CPC
-
SYCP3_HUMAN
A:
[81-223]
---------------------------------------------------------------
I
N
K
A
L
L
A
--
K
R
K
R
L
E
M
Y
T
K
A
S
L
K
T
S
N
--
Q
K
I
E
-------
H
V
W
K
T
Q
----
Q
D
Q
R
Q
K
L
N
Q
E
Y
----------
S
Q
--
Q
F
L
T
------
L
----------
F
Q
-
Q
W
-
D
L
D
---
M
Q
K
A
E
E
-
Q
E
E
K
I
L
N
M
F
R
---
Q
Q
Q
K
I
L
Q
Q
S
R
I
V
Q
S
Q
-
R
L
K
T
I
K
Q
L
-
Y
E
Q
F
I
K
S
M
E
E
L
E
K
N
H
D
N
L
L
T
-
G
A
Q
N
E
F
K
K
E
------
M
A
M
L
--
Q
K
K
I
M
M
E
T
Q
Q
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
56.78
16%
-17
- C1 -
4LQK
-
A46_VACCW
A:
[4-135]
----------------------------------------------------------------------------------------------------------
S
F
----
K
L
I
L
A
E
Y
I
R
H
R
----------
N
T
--
I
S
G
N
------
I
----------
Y
S
-
A
L
M
T
L
D
---
D
L
A
I
K
Q
Y
G
D
I
D
L
L
F
N
E
K
LKV
D
S
D
S
G
L
F
D
F
V
N
F
V
K
D
M
I
C
C
D
S
R
I
V
-
V
A
L
S
S
L
V
S
K
H
W
E
L
T
N
K
K
Y
R
C
M
A
L
A
E
H
I
S
D
S
---------
I
--
P
I
S
E
L
S
R
L
R
Y
N
L
S
K
Y
L
R
--------
G
H
T
E
S
I
--
E
D
K
F
-----
D
Y
----------------------------------------------------------------------------------------------------------------------------
35
Fugue
56.24
9%
11
- C1 -
3V3T
-
?
A:
[1-306]
------------------------------MKNK
I
V
F
A
P
I
G
Q
G
G
G
N
I
V
D
T
L
L
G
I
C
G
D
Y
N
A
L
F
I
N
T
S
K
K
D
L
--
D
S
L
K
H
A
K
H
T
Y
H
-
I
P
K
E
R
--
K
K
A
V
-------
G
Y
A
Q
T
Y
----
Y
K
Q
I
I
A
Q
I
M
E
K
----------
F
S
-----
S
------
C
----------
D
I
-
V
I
-
F
V
A
---
T
M
A
G
G
A
-
G
S
G
I
T
P
P
I
L
G
---
L
A
K
Q
M
Y
P
N
K
H
F
G
F
V
G
-
V
L
P
-
K
A
T
E
-
D
I
D
E
H
M
N
A
I
A
C
W
N
D
I
M
R
S
T
N
-
E
G
K
D
I
S
I
Y
L
------
L
D
N
N
--
K
R
E
K
E
S
D
I
N
K
E
F
A
T
L
F
N
D
F
M
N
M
S
E
S
H
A
E
G
V
V
D
E
D
E
I
S
-----
K
L
L
T
M
K
K
S
---
N
V
I
L
E
F
D
DKED
I
Q
V
A
L
A
K
S
L
K
E
----
S
I
F
A
EYTTNT
C
E
F
M
G
---
I
S
T
T
R
V
V
D
V
E
A
I
K
S
I
----------
V
G
Y
P
R
R
T
F
K
G
Y
N
S
K
K
N
I
V
V
A
T
GI
E
P
Q
K
T
T
V
Q
M
M
N
E
I
I
E
D
K
M
K
Q
R
--
11
PsiBlast_PDB
55.70
26%
22
- C2 -
2YQC
1
UAP1_CANAX
A:
[43-161]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
P
------
A
K
L
I
--
S
T
V
E
Q
A
I
Q
F
S
Q
----
S
R
N
F
T
Q
L
P
N
E
Q
T
A
S
T
L
--
D
L
S
K
-----
D
I
L
Q
N
W
T
E
L
G
L
K
A
I
G
-------
N
G
E
V
A
V
L
L
M
A
G
GQGT
R
L
G
S
------
S
A
P
K
G
CFN
I
E
L
P
S
Q
K
S
L
F
Q
I
Q
A
E
K
I
--------
L
K
I
E
Q
L
A
Q
Q
Y
L
K
-----------
S
T
K
K
P
------------------
12
PsiBlast_PDB
54.69
26%
22
- C2 -
2YQH
1
UAP1_CANAX
A:
[43-165]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
P
------
A
K
L
I
--
S
T
V
E
Q
A
I
Q
--------
R
N
F
T
Q
L
P
N
E
Q
T
A
S
T
L
--
D
L
S
K
-----
D
I
L
Q
N
W
T
E
L
G
L
K
A
I
G
-------
N
G
E
V
A
V
L
L
M
A
G
GQGT
R
L
G
S
------
S
A
P
K
G
CFN
I
E
L
P
S
Q
K
S
L
F
Q
I
Q
A
E
K
I
--------
L
K
I
E
Q
L
A
Q
Q
Y
L
K
-----------
S
T
K
K
P
------------------
39
Fugue
54.28
12%
14
- C1 -
1V74
-
IMMD_ECOLX
B:
[1-87]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
---
N
K
M
A
M
I
-
D
L
A
K
L
F
L
A
S
K
---
I
T
A
I
E
F
S
E
R
I
C
V
E
R
R
-
R
L
Y
G
V
K
D
L
-
S
P
N
I
L
N
C
G
E
E
L
F
M
A
A
E
R
F
E
--------
P
D
A
------
D
R
A
N
--
Y
E
I
D
D
N
G
L
K
V
E
V
R
S
I
L
E
K
F
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
52.64
26%
27
- C2 -
2YQS
4
UAP1_CANAX
A:
[43-164]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
P
------
A
K
L
I
--
S
T
V
E
Q
A
I
Q
F
S
-------
N
F
T
Q
L
P
N
E
Q
T
A
S
T
L
--
D
L
S
K
-----
D
I
L
Q
N
W
T
E
L
G
L
K
A
I
G
-------
N
G
E
V
A
V
L
L
M
A
G
GQGT
R
L
G
S
------
S
A
P
K
G
CFN
I
E
L
P
S
Q
K
S
L
F
Q
I
Q
A
E
K
I
--------
L
K
I
E
Q
L
A
Q
Q
Y
L
K
-----------
S
T
K
K
P
------------------
5
PsiBlast_PDB
52.04
32%
42
- C2 -
3GLI
2
DPO3X_ECOLI
B:
[235-296]
--------------------------------------------------------------------------------------------------------------------------------------------
S
------
L
----------
R
D
-
A
L
-
S
L
T
---
D
Q
A
I
A
S
-
G
D
G
Q
V
S
T
---------
Q
A
V
S
A
M
L
G
T
L
D
D
-----------
D
Q
A
L
S
L
V
E
A
M
V
E
A
N
G
E
R
V
M
-
A
L
I
N
E
A
A
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
51.94
13%
25
- C2 -
4ABM
-
CHM4B_HUMAN
A:
[25-94]
---------------------------------------------------------------------------------------
A
I
--
Q
R
L
R
-------
D
T
E
E
M
L
----
S
K
K
Q
E
F
L
E
K
K
I
----------
E
Q
--
E
L
T
A
------
A
----------
K
K
-
H
G
--
T
K
---
N
K
R
A
A
L
-
Q
A
L
K
R
K
K
R
Y
E
---
K
Q
L
A
Q
I
D
G
T
L
S
T
I
E
F
-
Q
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
50.74
15%
33
- C2 -
5APP
5
?
A:
[11-95]
--------------------------------------------------------------------
I
L
--
S
K
I
Y
H
I
E
N
E
I
A
R
I
K
K
L
I
--
Q
N
V
D
V
R
S
T
E
N
A
A
R
S
R
A
N
----
E
Q
K
I
A
E
N
K
K
A
I
----------
E
N
--
K
A
D
K
------
A
D
V
E
K
N
R
A
D
I
A
A
N
-
S
R
-
A
I
A
---
T
F
R
S
S
S
-
Q
N
I
A
A
L
T
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
50.66
32%
39
- C2 -
3GLG
2
DPO3X_ECOLI
B:
[235-296]
--------------------------------------------------------------------------------------------------------------------------------------------
S
------
L
----------
R
D
-
A
L
-
S
L
T
---
D
Q
A
I
A
S
-
G
D
G
Q
V
S
T
---------
Q
A
V
S
A
M
L
G
T
L
D
D
-----------
D
Q
A
L
S
L
V
E
A
M
V
E
A
N
G
E
R
V
M
-
A
L
I
N
E
A
A
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.59
32%
50
- C2 -
1XXH
1
DPO3X_ECOLI
B:
[213-274]
--------------------------------------------------------------------------------------------------------------------------------------------
S
------
L
----------
R
D
-
A
L
-
S
L
T
---
D
Q
A
I
A
S
-
G
D
G
Q
V
S
T
---------
Q
A
V
S
A
M
L
G
T
L
D
D
-----------
D
Q
A
L
S
L
V
E
A
M
V
E
A
N
G
E
R
V
M
-
A
L
I
N
E
A
A
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.00
32%
35
- C2 -
1JR3
1
DPO3X_ECOLI
A:
[213-274]
--------------------------------------------------------------------------------------------------------------------------------------------
S
------
L
----------
R
D
-
A
L
-
S
L
T
---
D
Q
A
I
A
S
-
G
D
G
Q
V
S
T
---------
Q
A
V
S
A
M
L
G
T
L
D
D
-----------
D
Q
A
L
S
L
V
E
A
M
V
E
A
N
G
E
R
V
M
-
A
L
I
N
E
A
A
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.55
32%
39
- C2 -
3GLF
2
DPO3X_ECOLI
B:
[235-296]
--------------------------------------------------------------------------------------------------------------------------------------------
S
------
L
----------
R
D
-
A
L
-
S
L
T
---
D
Q
A
I
A
S
-
G
D
G
Q
V
S
T
---------
Q
A
V
S
A
M
L
G
T
L
D
D
-----------
D
Q
A
L
S
L
V
E
A
M
V
E
A
N
G
E
R
V
M
-
A
L
I
N
E
A
A
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------