@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2753c: (2016-05-13 )
MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDGLVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGRSAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLCNAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASVLR
Atome Classification :
(50 SA)
.........10........20........30........40........50........60........70........80........90........100....--...110.......120.......130.......140.......150.......160-.......170.--....---..180.--.--.--..--.--.190-........200.......210.......220.......230.......240.......250........260......-.270...-.....280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTTV
G
F
D
V
A
A
R
L
G
T
L
L
T
A
M
VTPFSGDGSL
D
T
A
T
A
A
R
L
A
N
H
L
V
DQGCD
G
L
V
V
SGTTGESPTTTD
G
E
K
I
E
L
L
R
A
V
L
E
AVGDR
A
R
V
I
AGAGTYDT
A
H
S
I
R
L
A
K
A
C
AAEG--A
H
G
L
L
V
VTPYYSKPPQR
G
L
Q
A
H
F
T
AVADATEL
P
M
L
L
Y
DIPGRSAVPIE
P
D
T
I
R
A
L
A-SHP
N
I
V
GVKDA--KA
D
L
---HSG
A
Q
I
--
M
--A--DT--G--
L
A
Y
--YSGDDALN
L
P
W
L
AMG
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
FGSGDI
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
LG
G
V
T
LSKAG
L
R
L
Q
G
-ID-VGDP-RLPQVAA
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
SVLR
1
PsiBlast_PDB
97.99
99%
-109
- C3 -
1XXX
3
DAPA_MYCTU
A:
[8-303]
----
G
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
21
PsiBlast_CBE
97.60
99%
-107
- C3 -
1XXX
8
DAPA_MYCTU
H:
[8-303]
----
G
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
25
PsiBlast_CBE
97.57
99%
-109
- C3 -
1XXX
2
DAPA_MYCTU
D:
[9-303]
-----
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
24
PsiBlast_CBE
97.49
99%
-109
- C3 -
1XXX
2
DAPA_MYCTU
E:
[9-303]
-----
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
23
PsiBlast_CBE
97.29
99%
-110
- C3 -
1XXX
2
DAPA_MYCTU
F:
[8-303]
----
G
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
27
PsiBlast_CBE
97.14
99%
-108
- C3 -
1XXX
3
DAPA_MYCTU
B:
[9-303]
-----
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
22
PsiBlast_CBE
97.11
99%
-108
- C3 -
1XXX
2
DAPA_MYCTU
G:
[9-303]
-----
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
26
PsiBlast_CBE
96.58
99%
-107
- C3 -
1XXX
2
DAPA_MYCTU
C:
[8-303]
----
G
F
D
V
A
A
R
L
G
T
L
L
T
A
M
V
T
P
F
S
G
D
G
S
L
D
T
A
T
A
A
R
L
A
N
H
L
V
D
Q
G
C
D
G
L
V
V
S
G
T
T
G
E
S
P
T
T
T
D
G
E
K
I
E
L
L
R
A
V
L
E
A
V
G
D
R
A
R
V
I
A
G
A
G
T
Y
D
T
A
H
S
I
R
L
A
K
A
C
A
A
E
G
--
A
H
G
L
L
V
V
T
P
Y
Y
S
K
P
P
Q
R
G
L
Q
A
H
F
T
A
V
A
D
A
T
E
L
P
M
L
L
Y
D
I
P
G
R
S
A
V
P
I
E
P
D
T
I
R
A
L
A
-
S
H
P
N
I
V
G
V
K
D
A
--
K
A
D
L
---
H
S
G
A
Q
I
--
M
--
A
--
D
T
--
G
--
L
A
Y
--
Y
S
G
D
D
A
L
N
L
P
W
L
A
M
G
A
T
G
F
I
S
V
I
A
H
L
A
A
G
Q
L
R
E
L
L
S
A
F
G
S
G
D
I
A
T
A
R
K
I
N
I
A
V
A
P
L
C
N
A
M
-
S
R
L
G
G
V
T
L
S
K
A
G
L
R
L
Q
G
-
I
D
-
V
G
D
P
-
R
L
P
Q
V
A
A
T
P
E
Q
I
D
A
L
A
A
D
M
R
A
A
S
V
L
R
117
HHSearch
83.43
57%
-109
- C3 -
3CPR
-
DAPA_CORGL
A:
[9-303]
---
T
A
K
T
G
V
E
H
F
G
T
V
G
V
A
M
V
T
P
F
T
E
S
G
D
I
D
I
A
A
G
R
E
V
A
A
Y
L
V
D
K
G
L
D
S
L
V
L
A
G
T
T
G
E
S
P
T
T
T
A
A
E
K
L
E
L
L
K
A
V
R
E
E
V
G
D
R
A
K
L
I
A
G
V
G
T
N
N
T
R
T
S
V
E
L
A
E
A
A
A
S
A
G
--
A
D
G
L
L
V
V
T
P
Y
Y
S
K
P
S
Q
E
G
L
L
A
H
F
G
A
I
A
A
A
T
E
V
P
I
C
L
Y
D
I
P
G
R
S
G
I
P
I
E
S
D
T
M
R
R
L
S
-
E
L
P
T
I
L
A
V
-
D
A
--
K
G
D
L
---
V
A
A
T
S
L
--
I
--
K
--
E
T
--
G
--
L
A
W
--
Y
S
G
D
D
P
L
N
L
V
W
L
A
L
G
G
S
G
F
I
S
V
I
G
H
A
A
P
T
A
L
R
E
L
Y
T
S
F
E
E
G
D
L
V
R
A
R
E
I
N
A
K
L
S
P
L
V
A
A
Q
-
G
R
L
G
G
V
S
L
A
K
A
A
L
R
L
Q
G
-
I
N
-
V
G
D
P
-
R
L
P
I
M
A
P
N
E
Q
E
L
E
A
L
R
E
D
M
K
K
A
G
V
--
2
PsiBlast_PDB
83.15
58%
-111
- C3 -
3CPR
-
DAPA_CORGL
A:
[17-304]
-----------
F
G
T
V
G
V
A
M
V
T
P
F
T
E
S
G
D
I
D
I
A
A
G
R
E
V
A
A
Y
L
V
D
K
G
L
D
S
L
V
L
A
G
T
T
G
E
S
P
T
T
T
A
A
E
K
L
E
L
L
K
A
V
R
E
E
V
G
D
R
A
K
L
I
A
G
V
G
T
N
N
T
R
T
S
V
E
L
A
E
A
A
A
S
A
G
--
A
D
G
L
L
V
V
T
P
Y
Y
S
K
P
S
Q
E
G
L
L
A
H
F
G
A
I
A
A
A
T
E
V
P
I
C
L
Y
D
I
P
G
R
S
G
I
P
I
E
S
D
T
M
R
R
L
S
-
E
L
P
T
I
L
A
V
-
D
A
--
K
G
D
L
---
V
A
A
T
S
L
--
I
--
K
--
E
T
--
G
--
L
A
W
--
Y
S
G
D
D
P
L
N
L
V
W
L
A
L
G
G
S
G
F
I
S
V
I
G
H
A
A
P
T
A
L
R
E
L
Y
T
S
F
E
E
G
D
L
V
R
A
R
E
I
N
A
K
L
S
P
L
V
A
A
Q
-
G
R
L
G
G
V
S
L
A
K
A
A
L
R
L
Q
G
-
I
N
-
V
G
D
P
-
R
L
P
I
M
A
P
N
E
Q
E
L
E
A
L
R
E
D
M
K
K
A
G
V
L
-
29
PsiBlast_CBE
73.32
40%
-103
- C3 -
1XKY
3
?
C:
[13-298]
-----------
F
G
T
I
A
T
A
M
V
T
P
F
D
I
N
G
N
I
D
F
A
K
T
T
K
L
V
N
Y
L
I
D
N
G
T
T
A
I
V
V
G
G
T
T
G
E
S
P
T
L
T
S
E
E
K
V
A
L
Y
R
H
V
V
S
V
V
D
K
R
V
P
V
I
A
G
T
G
S
N
N
T
H
A
S
I
D
L
T
K
K
A
T
E
V
G
--
V
D
A
V
M
L
V
A
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
E
S
T
P
L
P
V
M
L
Y
N
V
P
G
R
S
I
V
Q
I
S
V
D
T
V
V
R
L
S
-
E
I
E
N
I
V
A
I
K
D
A
--
G
G
D
V
---
L
T
M
T
E
I
--
I
--
E
--
K
T
--
A
DD
F
A
V
--
Y
S
G
D
D
G
L
T
L
P
A
M
A
V
G
A
K
G
I
V
S
V
A
S
H
V
I
G
N
E
M
Q
E
M
I
A
A
F
Q
A
G
E
F
K
K
A
Q
K
L
H
Q
L
L
V
R
V
T
D
S
L
-
F
M
A
P
S
P
T
P
V
K
T
A
L
Q
M
V
G
-
L
D
-
V
G
S
V
-
R
L
P
L
L
P
L
T
E
E
E
R
V
T
L
Q
S
V
M
Q
S
-----
4
PsiBlast_PDB
73.08
40%
-104
- C3 -
1XL9
-
?
A:
[4-289]
-----------
F
G
T
I
A
T
A
M
V
T
P
F
D
I
N
G
N
I
D
F
A
K
T
T
K
L
V
N
Y
L
I
D
N
G
T
T
A
I
V
V
G
G
T
T
G
E
S
P
T
L
T
S
E
E
K
V
A
L
Y
R
H
V
V
S
V
V
D
K
R
V
P
V
I
A
G
T
G
S
N
N
T
H
A
S
I
D
L
T
K
K
A
T
E
V
G
--
V
D
A
V
M
L
V
A
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
E
S
T
P
L
P
V
M
L
Y
N
V
P
G
R
S
I
V
Q
I
S
V
D
T
V
V
R
L
S
-
E
I
E
N
I
V
A
I
K
D
A
--
G
G
D
V
---
L
T
M
T
E
I
--
I
--
E
--
K
T
--
A
DD
F
A
V
--
Y
S
G
D
D
G
L
T
L
P
A
M
A
V
G
A
K
G
I
V
S
V
A
S
H
V
I
G
N
E
M
Q
E
M
I
A
A
F
Q
A
G
E
F
K
K
A
Q
K
L
H
Q
L
L
V
R
V
T
D
S
L
-
F
M
A
P
S
P
T
P
V
K
T
A
L
Q
M
V
G
-
L
D
-
V
G
S
V
-
R
L
P
L
L
P
L
T
E
E
E
R
V
T
L
Q
S
V
M
Q
S
-----
3
PsiBlast_PDB
72.76
40%
-102
- C3 -
1XKY
2
?
A:
[13-298]
-----------
F
G
T
I
A
T
A
M
V
T
P
F
D
I
N
G
N
I
D
F
A
K
T
T
K
L
V
N
Y
L
I
D
N
G
T
T
A
I
V
V
G
G
T
T
G
E
S
P
T
L
T
S
E
E
K
V
A
L
Y
R
H
V
V
S
V
V
D
K
R
V
P
V
I
A
G
T
G
S
N
N
T
H
A
S
I
D
L
T
K
K
A
T
E
V
G
--
V
D
A
V
M
L
V
A
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
E
S
T
P
L
P
V
M
L
Y
N
V
P
G
R
S
I
V
Q
I
S
V
D
T
V
V
R
L
S
-
E
I
E
N
I
V
A
I
K
D
A
--
G
G
D
V
---
L
T
M
T
E
I
--
I
--
E
--
K
T
--
A
DD
F
A
V
--
Y
S
G
D
D
G
L
T
L
P
A
M
A
V
G
A
K
G
I
V
S
V
A
S
H
V
I
G
N
E
M
Q
E
M
I
A
A
F
Q
A
G
E
F
K
K
A
Q
K
L
H
Q
L
L
V
R
V
T
D
S
L
-
F
M
A
P
S
P
T
P
V
K
T
A
L
Q
M
V
G
-
L
D
-
V
G
S
V
-
R
L
P
L
L
P
L
T
E
E
E
R
V
T
L
Q
S
V
M
Q
S
-----
116
HHSearch
72.31
40%
-101
- C3 -
1XKY
2
?
A:
[10-300]
--------
M
I
D
F
G
T
I
A
T
A
M
V
T
P
F
D
I
N
G
N
I
D
F
A
K
T
T
K
L
V
N
Y
L
I
D
N
G
T
T
A
I
V
V
G
G
T
T
G
E
S
P
T
L
T
S
E
E
K
V
A
L
Y
R
H
V
V
S
V
V
D
K
R
V
P
V
I
A
G
T
G
S
N
N
T
H
A
S
I
D
L
T
K
K
A
T
E
V
G
--
V
D
A
V
M
L
V
A
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
E
S
T
P
L
P
V
M
L
Y
N
V
P
G
R
S
I
V
Q
I
S
V
D
T
V
V
R
L
S
-
E
I
E
N
I
V
A
I
K
D
A
--
G
G
D
V
---
L
T
M
T
E
I
--
I
--
E
--
K
T
AD
D
--
F
A
V
--
Y
S
G
D
D
G
L
T
L
P
A
M
A
V
G
A
K
G
I
V
S
V
A
S
H
V
I
G
N
E
M
Q
E
M
I
A
A
F
Q
A
G
E
F
K
K
A
Q
K
L
H
Q
L
L
V
R
V
T
D
S
L
-
F
M
A
P
S
P
T
P
V
K
T
A
L
Q
M
V
G
-
L
D
-
V
G
S
V
-
R
L
P
L
L
P
L
T
E
E
E
R
V
T
L
Q
S
V
M
Q
S
I
P
---
30
PsiBlast_CBE
72.18
40%
-104
- C3 -
1XKY
3
?
B:
[13-298]
-----------
F
G
T
I
A
T
A
M
V
T
P
F
D
I
N
G
N
I
D
F
A
K
T
T
K
L
V
N
Y
L
I
D
N
G
T
T
A
I
V
V
G
G
T
T
G
E
S
P
T
L
T
S
E
E
K
V
A
L
Y
R
H
V
V
S
V
V
D
K
R
V
P
V
I
A
G
T
G
S
N
N
T
H
A
S
I
D
L
T
K
K
A
T
E
V
G
--
V
D
A
V
M
L
V
A
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
E
S
T
P
L
P
V
M
L
Y
N
V
P
G
R
S
I
V
Q
I
S
V
D
T
V
V
R
L
S
-
E
I
E
N
I
V
A
I
K
D
A
--
G
G
D
V
---
L
T
M
T
E
I
--
I
--
E
--
K
T
--
A
DD
F
A
V
--
Y
S
G
D
D
G
L
T
L
P
A
M
A
V
G
A
K
G
I
V
S
V
A
S
H
V
I
G
N
E
M
Q
E
M
I
A
A
F
Q
A
G
E
F
K
K
A
Q
K
L
H
Q
L
L
V
R
V
T
D
S
L
-
F
M
A
P
S
P
T
P
V
K
T
A
L
Q
M
V
G
-
L
D
-
V
G
S
V
-
R
L
P
L
L
P
L
T
E
E
E
R
V
T
L
Q
S
V
M
Q
S
-----
28
PsiBlast_CBE
72.01
40%
-102
- C3 -
1XKY
2
?
D:
[13-298]
-----------
F
G
T
I
A
T
A
M
V
T
P
F
D
I
N
G
N
I
D
F
A
K
T
T
K
L
V
N
Y
L
I
D
N
G
T
T
A
I
V
V
G
G
T
T
G
E
S
P
T
L
T
S
E
E
K
V
A
L
Y
R
H
V
V
S
V
V
D
K
R
V
P
V
I
A
G
T
G
S
N
N
T
H
A
S
I
D
L
T
K
K
A
T
E
V
G
--
V
D
A
V
M
L
V
A
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
E
S
T
P
L
P
V
M
L
Y
N
V
P
G
R
S
I
V
Q
I
S
V
D
T
V
V
R
L
S
-
E
I
E
N
I
V
A
I
K
D
A
--
G
G
D
V
---
L
T
M
T
E
I
--
I
--
E
--
K
T
--
A
DD
F
A
V
--
Y
S
G
D
D
G
L
T
L
P
A
M
A
V
G
A
K
G
I
V
S
V
A
S
H
V
I
G
N
E
M
Q
E
M
I
A
A
F
Q
A
G
E
F
K
K
A
Q
K
L
H
Q
L
L
V
R
V
T
D
S
L
-
F
M
A
P
S
P
T
P
V
K
T
A
L
Q
M
V
G
-
L
D
-
V
G
S
V
-
R
L
P
L
L
P
L
T
E
E
E
R
V
T
L
Q
S
V
M
Q
S
-----
93
PsiBlast_CBE
70.11
33%
-100
- C3 -
3G0S
4
DAPA_SALTY
A:
[22-316]
-------
S
N
A
M
F
T
G
S
I
V
A
L
V
T
P
M
D
E
K
G
N
V
S
R
S
C
L
K
K
L
I
D
Y
H
V
A
N
G
T
S
A
I
V
S
V
G
T
T
G
E
S
A
T
L
S
H
D
E
H
G
D
V
V
M
M
T
L
E
L
A
D
G
R
I
P
V
I
A
G
T
G
A
N
A
T
A
E
A
I
S
L
T
Q
R
F
N
D
S
G
--
I
V
G
C
L
T
V
T
P
Y
Y
N
R
P
T
Q
E
G
L
F
Q
H
F
K
A
I
A
E
H
T
D
L
P
Q
I
L
Y
N
V
P
S
R
T
G
C
D
M
L
P
E
T
V
G
R
L
A
-
E
I
K
N
I
I
A
I
K
E
A
--
T
G
N
L
T
R
V
H
Q
I
K
E
L
--
V
--
S
--
D
---
D
--
F
I
L
--
L
S
G
D
D
A
S
A
L
D
F
M
Q
L
G
G
H
G
V
I
S
V
T
A
N
V
A
A
R
E
M
A
D
M
C
K
L
A
A
E
G
Q
F
A
E
A
R
A
I
N
Q
R
L
M
P
L
H
N
K
L
-
F
V
E
P
N
P
I
P
V
K
W
A
C
K
A
L
G
-
L
V
-
A
T
D
T
L
R
L
P
M
T
P
I
T
D
H
G
R
D
I
V
K
A
A
L
Q
H
A
G
L
L
-
92
PsiBlast_CBE
69.88
33%
-102
- C3 -
3G0S
4
DAPA_SALTY
B:
[23-316]
--------
N
A
M
F
T
G
S
I
V
A
L
V
T
P
M
D
E
K
G
N
V
S
R
S
C
L
K
K
L
I
D
Y
H
V
A
N
G
T
S
A
I
V
S
V
G
T
T
G
E
S
A
T
L
S
H
D
E
H
G
D
V
V
M
M
T
L
E
L
A
D
G
R
I
P
V
I
A
G
T
G
A
N
A
T
A
E
A
I
S
L
T
Q
R
F
N
D
S
G
--
I
V
G
C
L
T
V
T
P
Y
Y
N
R
P
T
Q
E
G
L
F
Q
H
F
K
A
I
A
E
H
T
D
L
P
Q
I
L
Y
N
V
P
S
R
T
G
C
D
M
L
P
E
T
V
G
R
L
A
-
E
I
K
N
I
I
A
I
K
E
A
--
T
G
N
L
T
R
V
H
Q
I
K
E
L
--
V
--
S
--
D
---
D
--
F
I
L
--
L
S
G
D
D
A
S
A
L
D
F
M
Q
L
G
G
H
G
V
I
S
V
T
A
N
V
A
A
R
E
M
A
D
M
C
K
L
A
A
E
G
Q
F
A
E
A
R
A
I
N
Q
R
L
M
P
L
H
N
K
L
-
F
V
E
P
N
P
I
P
V
K
W
A
C
K
A
L
G
-
L
V
-
A
T
D
T
L
R
L
P
M
T
P
I
T
D
H
G
R
D
I
V
K
A
A
L
Q
H
A
G
L
L
-
137
HHSearch
69.78
35%
-102
- C3 -
2YXG
-
DAPA_METJA
A:
[2-288]
-----------
F
K
G
V
Y
P
A
I
I
T
P
F
K
N
-
K
E
V
D
F
D
G
L
E
E
N
I
N
F
L
I
E
N
G
V
S
G
I
V
A
V
G
T
T
G
E
S
P
T
L
S
H
E
E
H
K
K
V
I
E
K
V
V
D
V
V
N
G
R
V
Q
V
I
A
G
A
G
S
N
C
T
E
E
A
I
E
L
S
V
F
A
E
D
V
G
--
A
D
A
V
L
S
I
T
P
Y
Y
N
K
P
T
Q
E
G
L
R
K
H
F
G
K
V
A
E
S
I
N
L
P
I
V
L
Y
N
V
P
S
R
T
A
V
N
L
E
P
K
T
V
K
L
L
A
E
E
Y
S
N
I
S
A
V
K
E
A
--
N
P
N
L
---
S
Q
V
S
E
L
--
I
--
H
--
D
A
--
K
--
I
T
V
--
L
S
G
N
D
E
L
T
L
P
I
I
A
L
G
G
K
G
V
I
S
V
V
A
N
I
V
P
K
E
F
V
E
M
V
N
Y
A
L
E
G
D
F
E
K
A
R
E
I
H
Y
K
L
F
P
L
M
K
A
M
-
F
I
E
T
N
P
I
P
V
K
T
A
L
N
M
M
G
-
R
P
-
A
G
E
L
-
R
L
P
L
C
E
M
S
E
E
H
K
K
I
L
E
N
V
L
K
D
L
G
L
--
132
HHSearch
68.84
33%
-99
- C3 -
2EHH
1
DAPA_AQUAE
A:
[1-291]
----------
M
F
Q
G
S
I
V
A
L
I
T
P
F
K
E
-
G
E
V
D
Y
E
A
L
G
N
L
I
E
F
H
V
D
N
G
T
D
A
I
L
V
C
G
T
T
G
E
S
P
T
L
T
F
E
E
H
E
K
V
I
E
F
A
V
K
R
A
A
G
R
I
K
V
I
A
G
T
G
G
N
A
T
H
E
A
V
H
L
T
A
H
A
K
E
V
G
--
A
D
G
A
L
V
V
V
P
Y
Y
N
K
P
T
Q
R
G
L
Y
E
H
F
K
T
V
A
Q
E
V
D
I
P
I
I
I
Y
N
I
P
S
R
T
C
V
E
I
S
V
D
T
M
F
K
L
A
S
E
C
E
N
I
V
A
S
K
E
S
--
T
P
N
M
---
D
R
I
S
E
I
--
V
--
K
--
R
L
GE
S
--
F
S
V
--
L
S
G
D
D
S
L
T
L
P
M
M
A
L
G
A
K
G
V
I
S
V
A
N
N
V
M
P
R
E
V
K
E
L
I
R
A
A
L
E
G
D
F
R
R
A
R
E
I
H
Y
Y
L
H
D
L
F
K
V
L
-
F
I
E
T
N
P
I
P
V
K
T
A
C
W
M
L
G
-
M
C
-
E
K
E
F
-
R
L
P
L
T
E
M
S
P
E
N
E
N
K
L
R
E
V
L
K
K
Y
N
L
P
-
73
PsiBlast_CBE
67.26
36%
-98
- C3 -
3S8H
1
DAPA_PSEAE
A:
[6-291]
---------------
M
V
A
L
V
T
P
F
D
A
Q
G
R
L
D
W
D
S
L
A
K
L
V
D
F
H
L
Q
D
G
T
N
A
I
V
A
V
G
T
T
G
E
S
A
T
L
D
V
E
E
H
I
Q
V
V
R
R
V
V
D
Q
V
K
G
R
I
P
V
I
A
G
T
G
A
N
S
T
R
E
A
V
A
L
T
E
A
A
K
S
G
G
--
A
D
A
C
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
M
Y
Q
H
F
R
H
I
A
E
A
V
A
I
P
Q
I
L
Y
N
V
P
G
R
T
S
C
D
M
L
P
E
T
V
E
R
L
S
-
K
V
P
N
I
I
G
I
K
E
A
--
T
G
D
L
---
Q
R
A
K
E
V
--
I
--
E
--
R
V
--
G
--
K
D
F
L
V
Y
S
G
D
D
A
T
A
V
E
L
M
L
L
G
G
K
G
N
I
S
V
T
A
N
V
A
P
R
A
M
S
D
L
C
A
A
A
M
R
G
D
A
A
A
A
R
A
I
N
D
R
L
M
P
L
H
K
A
L
-
F
I
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
-
L
I
-
P
E
G
I
-
R
L
P
L
T
W
L
S
P
H
C
H
D
P
L
R
Q
A
M
R
Q
T
G
V
L
-
81
PsiBlast_CBE
66.16
34%
-97
- C3 -
4ICN
6
?
A:
[12-297]
---------------
I
V
A
L
I
T
P
L
N
S
D
G
T
V
D
Y
T
S
L
E
K
L
V
E
Y
H
I
T
E
G
T
D
A
I
V
A
V
G
T
T
G
E
S
A
T
L
P
I
S
E
H
I
A
V
V
G
Q
T
V
K
F
A
S
G
R
I
P
V
I
G
G
N
G
A
N
A
T
A
E
A
I
E
L
T
K
A
Q
N
K
L
G
--
V
A
A
M
L
G
V
T
P
Y
Y
N
K
P
S
P
K
G
L
I
A
H
Y
T
A
V
A
A
S
T
D
I
P
Q
I
L
Y
N
V
P
G
R
T
A
V
D
M
L
P
E
T
I
A
Q
L
V
-
E
V
P
N
I
I
G
V
K
D
A
--
T
G
D
V
---
A
R
V
K
Q
L
R
D
L
--
C
--
G
N
--
D
--
F
L
L
--
Y
S
G
D
D
A
T
A
R
E
F
L
T
L
G
G
D
G
V
I
S
V
A
N
N
I
V
P
K
L
F
K
L
M
C
D
A
A
L
A
G
D
T
Q
A
A
M
A
A
E
D
Q
I
K
G
L
F
S
A
L
F
C
E
A
N
P
I
P
V
K
W
A
A
H
K
M
G
L
-
I
S
-
Q
G
D
I
-
R
L
P
L
T
E
L
S
T
E
F
H
G
L
L
L
D
A
M
K
N
A
R
I
--
72
PsiBlast_CBE
65.76
36%
-94
- C3 -
3S8H
1
DAPA_PSEAE
B:
[6-291]
---------------
M
V
A
L
V
T
P
F
D
A
Q
G
R
L
D
W
D
S
L
A
K
L
V
D
F
H
L
Q
D
G
T
N
A
I
V
A
V
G
T
T
G
E
S
A
T
L
D
V
E
E
H
I
Q
V
V
R
R
V
V
D
Q
V
K
G
R
I
P
V
I
A
G
T
G
A
N
S
T
R
E
A
V
A
L
T
E
A
A
K
S
G
G
--
A
D
A
C
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
M
Y
Q
H
F
R
H
I
A
E
A
V
A
I
P
Q
I
L
Y
N
V
P
G
R
T
S
C
D
M
L
P
E
T
V
E
R
L
S
-
K
V
P
N
I
I
G
I
K
E
A
--
T
G
D
L
---
Q
R
A
K
E
V
--
I
--
E
--
R
V
--
G
--
K
D
F
LV
Y
S
G
D
D
A
T
A
V
E
L
M
L
L
G
G
K
G
N
I
S
V
T
A
N
V
A
P
R
A
M
S
D
L
C
A
A
A
M
R
G
D
A
A
A
A
R
A
I
N
D
R
L
M
P
L
H
K
A
L
-
F
I
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
-
L
I
-
P
E
G
I
-
R
L
P
L
T
W
L
S
P
H
C
H
D
P
L
R
Q
A
M
R
Q
T
G
V
L
-
80
PsiBlast_CBE
65.70
34%
-97
- C3 -
4ICN
4
?
B:
[12-297]
---------------
I
V
A
L
I
T
P
L
N
S
D
G
T
V
D
Y
T
S
L
E
K
L
V
E
Y
H
I
T
E
G
T
D
A
I
V
A
V
G
T
T
G
E
S
A
T
L
P
I
S
E
H
I
A
V
V
G
Q
T
V
K
F
A
S
G
R
I
P
V
I
G
G
N
G
A
N
A
T
A
E
A
I
E
L
T
K
A
Q
N
K
L
G
--
V
A
A
M
L
G
V
T
P
Y
Y
N
K
P
S
P
K
G
L
I
A
H
Y
T
A
V
A
A
S
T
D
I
P
Q
I
L
Y
N
V
P
G
R
T
A
V
D
M
L
P
E
T
I
A
Q
L
V
-
E
V
P
N
I
I
G
V
K
D
A
--
T
G
D
V
---
A
R
V
K
Q
L
R
D
L
--
C
--
G
N
--
D
--
F
L
L
--
Y
S
G
D
D
A
T
A
R
E
F
L
T
L
G
G
D
G
V
I
S
V
A
N
N
I
V
P
K
L
F
K
L
M
C
D
A
A
L
A
G
D
T
Q
A
A
M
A
A
E
D
Q
I
K
G
L
F
S
A
L
F
C
E
A
N
P
I
P
V
K
W
A
A
H
K
M
G
L
-
I
S
-
Q
G
D
I
-
R
L
P
L
T
E
L
S
T
E
F
H
G
L
L
L
D
A
M
K
N
A
R
I
--
122
HHSearch
65.53
34%
-99
- C3 -
4PFM
5
?
A:
[1-293]
---------
H
M
I
N
G
S
I
V
A
L
I
T
P
L
N
S
D
G
T
V
D
Y
T
S
L
E
K
L
V
E
Y
H
I
T
E
G
T
D
A
I
V
A
V
G
T
T
G
E
S
A
T
L
P
I
S
E
H
I
A
V
V
G
Q
T
V
K
F
A
S
G
R
I
P
V
I
G
G
N
G
A
N
A
T
A
E
A
I
E
L
T
K
A
Q
N
K
L
G
--
V
A
A
M
L
G
V
T
P
Y
Y
N
K
P
S
P
K
G
L
I
A
H
Y
T
A
V
A
A
S
T
D
I
P
Q
I
L
Y
N
V
P
G
R
T
A
V
D
M
L
P
E
T
I
A
Q
L
V
-
E
V
P
N
I
I
G
V
-
D
A
--
T
G
D
V
---
A
R
V
K
Q
L
--
R
--
D
--
L
C
GN
D
--
F
L
L
--
Y
S
G
D
D
A
T
A
R
E
F
L
T
L
G
G
D
G
V
I
S
V
A
N
N
I
V
P
K
L
F
K
L
M
C
D
A
A
L
A
G
D
T
Q
A
A
M
A
A
E
D
Q
I
K
G
L
F
S
A
L
-
F
C
E
A
N
P
I
P
V
K
W
A
A
H
K
M
G
-
L
I
S
Q
G
D
I
-
R
L
P
L
T
E
L
S
T
E
F
H
G
L
L
L
D
A
M
K
N
A
R
I
E
-
44
PsiBlast_CBE
65.41
41%
-107
- C3 -
4I7U
2
DAPA_AGRFC
D:
[20-271]
---------------
I
P
A
L
I
T
P
F
T
D
N
G
A
V
D
E
Q
A
F
A
A
H
V
E
W
Q
I
A
E
G
S
N
G
L
V
P
V
G
T
T
G
E
S
P
T
L
S
H
D
E
H
K
R
V
V
E
L
C
I
E
V
A
A
K
R
V
P
V
I
A
G
A
G
S
N
N
T
D
E
A
I
E
L
A
L
H
A
Q
D
A
G
--
A
D
A
L
L
V
V
T
P
Y
Y
N
K
P
T
Q
K
G
L
F
A
H
F
S
A
V
A
E
A
V
K
L
P
I
V
I
Y
N
I
P
P
R
S
V
V
D
M
S
P
E
T
M
G
A
L
V
K
A
H
K
N
I
V
G
V
K
D
A
TG
K
L
D
R
---
V
S
E
Q
R
I
--
S
--
C
--
G
K
--
D
--
F
I
Q
--
L
S
G
E
D
S
T
A
L
G
F
N
A
H
G
G
V
G
C
I
S
V
S
A
N
V
A
P
R
L
C
S
E
F
Q
A
A
M
L
A
G
D
Y
A
K
A
L
E
Y
Q
D
R
L
M
P
L
H
R
A
I
-
F
M
E
P
G
V
C
G
T
K
Y
A
L
---------------------------------------
129
HHSearch
64.74
35%
-92
- C3 -
3FLU
13
DAPA_NEIMB
A:
[4-296]
-------
P
F
T
M
L
Q
G
S
L
V
A
L
I
T
P
M
N
Q
D
G
S
I
H
Y
E
Q
L
R
D
L
I
D
W
H
I
E
N
G
T
D
G
I
V
A
V
G
T
T
G
E
S
A
T
L
S
V
E
E
H
T
A
V
I
E
A
V
V
K
H
V
A
K
R
V
P
V
I
A
G
T
G
A
N
N
T
V
E
A
I
A
L
S
Q
A
A
E
K
A
G
--
A
D
Y
T
L
S
V
V
P
Y
Y
N
K
P
S
Q
E
G
I
Y
Q
H
F
K
T
I
A
E
A
T
S
I
P
M
I
I
Y
N
V
P
G
R
T
V
V
S
M
T
N
D
T
I
L
R
L
A
-
E
I
P
N
I
V
G
V
K
E
A
--
S
G
N
I
---
G
S
N
I
E
L
--
I
--
N
--
R
A
PE
G
--
F
V
V
--
L
S
G
D
D
H
T
A
L
P
F
M
L
C
G
G
H
G
V
I
T
V
A
A
N
A
A
P
K
L
F
A
D
M
C
R
A
A
L
Q
G
D
I
A
L
A
R
E
L
N
D
R
L
I
P
I
Y
D
T
M
-
F
C
E
P
S
P
A
A
P
K
W
A
V
S
A
L
G
-
R
C
-
E
P
H
V
-
R
L
P
L
V
P
L
T
E
N
G
Q
A
K
V
R
A
A
L
K
A
S
G
Q
--
60
PsiBlast_CBE
64.49
36%
-102
- C3 -
3PUL
8
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
126
HHSearch
64.47
34%
-94
- C3 -
3TAK
3
?
A:
[2-290]
-----------
I
Q
G
S
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
--
D
--
A
L
N
G
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
-
L
I
-
D
T
G
I
-
R
L
P
L
T
P
L
A
E
Q
Y
R
E
P
L
R
N
A
L
K
D
A
G
I
--
124
HHSearch
63.59
33%
-95
- C3 -
3SI9
3
DAPA_BARHE
A:
[21-314]
---------
S
M
L
K
G
A
V
T
A
L
I
T
P
F
D
D
N
G
A
I
D
E
K
A
F
C
N
F
V
E
W
Q
I
T
Q
G
I
N
G
V
S
P
V
G
T
T
G
E
S
P
T
L
T
H
E
E
H
K
R
I
I
E
L
C
V
E
Q
V
A
K
R
V
P
V
V
A
G
A
G
S
N
S
T
S
E
A
V
E
L
A
K
H
A
E
K
A
G
--
A
D
A
V
L
V
V
T
P
Y
Y
N
R
P
N
Q
R
G
L
Y
T
H
F
S
S
I
A
K
A
I
S
I
P
I
I
I
Y
N
I
P
S
R
S
V
I
D
M
A
V
E
T
M
R
D
L
C
R
D
F
K
N
I
I
G
V
K
D
A
--
T
G
K
I
---
E
R
A
S
E
Q
--
R
--
E
--
K
C
GK
D
--
F
V
Q
--
L
S
G
D
D
C
T
A
L
G
F
N
A
H
G
G
V
G
C
I
S
V
S
S
N
V
A
P
K
L
C
A
Q
L
H
A
A
C
L
C
S
D
Y
K
T
A
L
K
L
N
D
L
L
M
P
L
N
R
A
V
-
F
I
E
P
S
P
A
G
I
K
Y
A
A
A
K
L
G
-
L
C
-
G
T
I
V
-
R
S
P
I
V
P
L
S
D
T
T
K
K
I
I
D
E
A
L
Y
H
A
G
L
L
K
31
PsiBlast_CBE
63.52
38%
-99
- C3 -
3VFL
7
?
B:
[11-288]
--------------
I
I
T
A
F
I
T
P
F
H
E
D
G
S
I
N
F
D
A
I
P
A
L
I
E
H
L
L
A
H
H
T
D
G
I
L
L
A
G
T
T
A
E
S
P
T
L
T
H
D
E
E
L
E
L
F
A
A
V
Q
K
V
V
N
G
R
V
P
L
I
A
G
V
G
T
N
D
T
R
D
S
I
E
F
V
K
E
V
A
E
F
G
GF
A
A
G
L
A
I
V
-
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
D
A
S
D
L
P
I
I
I
Y
N
I
P
G
R
V
V
V
E
L
T
P
E
T
M
L
R
L
A
-
D
H
P
N
I
I
G
V
K
E
C
--
T
S
-
L
---
A
N
M
A
Y
L
--
I
--
E
--
H
K
--
P
--
E
E
F
LI
Y
T
G
E
D
G
D
A
F
H
A
M
N
L
G
A
D
G
V
I
S
V
A
S
H
T
N
G
D
E
M
H
E
M
F
T
A
I
A
E
S
D
M
K
K
A
A
A
I
Q
R
K
F
I
P
K
V
N
A
L
-
F
S
Y
P
S
P
A
P
V
K
A
I
L
N
Y
M
G
-
F
E
-
A
G
P
T
-
R
L
P
L
V
P
A
P
E
E
D
V
--------------
17
PsiBlast_PDB
63.39
36%
-100
- C3 -
3RK8
8
?
A:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
D
A
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
62
PsiBlast_CBE
63.04
36%
-101
- C3 -
3PUD
6
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
5
PsiBlast_PDB
62.96
38%
-100
- C3 -
3VFL
7
?
A:
[11-286]
--------------
I
I
T
A
F
I
T
P
F
H
E
D
G
S
I
N
F
D
A
I
P
A
L
I
E
H
L
L
A
H
H
T
D
G
I
L
L
A
G
T
T
A
E
S
P
T
L
T
H
D
E
E
L
E
L
F
A
A
V
Q
K
V
V
N
G
R
V
P
L
I
A
G
V
G
T
N
D
T
R
D
S
I
E
F
V
K
E
V
A
E
F
G
GF
A
A
G
L
A
I
V
-
P
Y
Y
N
K
P
S
Q
E
G
M
Y
Q
H
F
K
A
I
A
D
A
S
D
L
P
I
I
I
Y
N
I
P
G
R
V
V
V
E
L
T
P
E
T
M
L
R
L
A
-
D
H
P
N
I
I
G
V
K
E
C
--
T
S
-
L
---
A
N
M
A
Y
L
--
I
--
E
--
H
K
--
P
--
E
E
F
L
I
Y
T
G
E
D
G
D
A
F
H
A
M
N
L
G
A
D
G
V
I
S
V
A
S
H
T
N
G
D
E
M
H
E
M
F
T
A
I
A
E
S
D
M
K
K
A
A
A
I
Q
R
K
F
I
P
K
V
N
A
L
-
F
S
Y
P
S
P
A
P
V
K
A
I
L
N
Y
M
G
-
F
E
-
A
G
P
T
-
R
L
P
L
V
P
A
P
E
E
D
V
--------------
18
PsiBlast_PDB
62.37
36%
-99
- C3 -
3TAK
3
?
A:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
D
A
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
58
PsiBlast_CBE
62.34
36%
-99
- C3 -
3TAK
5
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
53
PsiBlast_CBE
62.06
36%
-100
- C3 -
3UQN
2
?
A:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
D
A
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
61
PsiBlast_CBE
61.92
36%
-102
- C3 -
3PUE
6
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
59
PsiBlast_CBE
61.77
36%
-97
- C3 -
3RK8
8
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
52
PsiBlast_CBE
61.59
36%
-99
- C3 -
3UQN
2
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
20
PsiBlast_PDB
61.44
36%
-97
- C3 -
3TDF
1
?
A:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
D
A
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
56
PsiBlast_CBE
61.37
36%
-99
- C3 -
3TDF
1
?
B:
[6-269]
---------------
I
V
A
I
V
T
P
M
L
K
D
G
G
V
D
W
K
S
L
E
K
L
V
E
W
H
I
E
Q
G
T
N
S
I
V
A
V
G
T
T
G
E
A
S
T
L
S
M
E
E
H
T
Q
V
I
K
E
I
I
R
V
A
N
K
R
I
P
I
I
A
G
T
G
A
N
S
T
R
E
A
I
E
L
T
K
A
A
K
D
L
G
--
A
D
A
A
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
L
Y
Q
H
Y
K
A
I
A
E
A
V
E
L
P
L
I
L
Y
N
V
P
G
R
T
G
V
D
L
S
N
D
T
A
V
R
L
A
-
E
I
P
N
I
V
G
I
K
D
A
--
T
G
D
V
---
P
R
G
K
A
L
--
I
DA
L
--
N
G
--
K
--
M
A
V
--
Y
S
G
D
D
E
T
A
W
E
L
M
L
L
G
A
D
G
N
I
S
V
T
A
N
I
A
P
K
A
M
S
E
V
C
A
V
A
I
A
K
D
E
Q
Q
A
K
T
L
N
N
K
I
A
N
L
H
N
I
L
-
F
C
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
D
-
T
G
-
I
-
R
L
P
-----------------------
64
PsiBlast_CBE
59.36
39%
-106
- C3 -
3DI1
1
DAPA_STAAC
A:
[11-227]
-----------------
A
L
T
T
P
F
T
N
N
-
K
V
N
I
E
A
L
K
T
H
V
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
R
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
R
I
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
65
PsiBlast_CBE
58.18
39%
-103
- C3 -
3DI0
1
DAPA_STAAC
B:
[11-227]
-----------------
A
L
T
T
P
F
T
N
N
-
K
V
N
I
E
A
L
K
T
H
V
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
R
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
RI
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
66
PsiBlast_CBE
57.33
39%
-106
- C3 -
3DI0
1
DAPA_STAAC
A:
[11-227]
-----------------
A
L
T
T
P
F
T
N
N
-
K
V
N
I
E
A
L
K
T
H
V
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
R
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
R
I
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
63
PsiBlast_CBE
56.66
39%
-101
- C3 -
3DI1
1
DAPA_STAAC
B:
[11-227]
-----------------
A
L
T
T
P
F
T
N
N
-
K
V
N
I
E
A
L
K
T
H
V
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
R
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
R
I
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
68
PsiBlast_CBE
56.46
40%
-102
- C3 -
3DAQ
5
DAPA_STAAR
C:
[10-226]
-----------------
A
L
T
T
P
F
T
N
N
K
V
N
L
E
A
L
K
A
H
V
-
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
L
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
RI
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
67
PsiBlast_CBE
56.07
40%
-101
- C3 -
3DAQ
4
DAPA_STAAR
D:
[10-226]
-----------------
A
L
T
T
P
F
T
N
N
K
V
N
L
E
A
L
K
A
H
V
-
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
L
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
RI
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
69
PsiBlast_CBE
56.04
40%
-100
- C3 -
3DAQ
5
DAPA_STAAR
B:
[10-226]
-----------------
A
L
T
T
P
F
T
N
N
K
V
N
L
E
A
L
K
A
H
V
-
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
L
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
RI
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------
70
PsiBlast_CBE
55.99
40%
-102
- C3 -
3DAQ
4
DAPA_STAAR
A:
[10-226]
-----------------
A
L
T
T
P
F
T
N
N
K
V
N
L
E
A
L
K
A
H
V
-
N
F
L
L
E
N
N
A
Q
A
I
I
V
N
G
T
T
A
E
S
P
T
L
T
T
D
E
K
E
L
I
L
K
T
V
I
D
L
V
D
K
R
V
P
V
I
A
G
T
G
T
N
D
T
E
K
S
I
Q
A
S
I
Q
A
K
A
L
G
--
A
D
A
I
M
L
I
T
P
Y
Y
N
K
T
N
Q
R
G
L
V
K
H
F
E
A
I
A
D
A
V
K
L
P
V
V
L
Y
N
V
P
S
R
T
N
M
T
I
E
P
E
T
V
E
I
L
S
-
Q
H
P
Y
I
V
A
L
K
D
A
--
T
N
D
F
---
E
Y
L
E
E
V
--
K
--
K
R
I
D
T
--
N
S-
F
A
L
--
Y
S
G
N
D
D
N
V
V
E
Y
Y
Q
R
G
G
Q
G
V
I
S
V
I
A
N
V
I
P
K
E
F
Q
A
L
Y
D
A
Q
Q
S
G
------------------------------------------------------------------------