@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2877c: (2016-05-14 )
MNEALIGLAFAAGLVAALNPCGFAMLPAYLLLVVYGQDSAGRTGPLSAVGRAAAATVGMALGFLTVFGIFGALTISAATAVQRYLPYATVLIGLALIALGGWLLLGRGLTALTPRSLGVRWAPTVRLGSMYGYGISYAVASLSCTIGPFLAVTGAGLRGGSVVGSVAIYLAYVAGLTLVVGVLAVAAATASSALADRLRRILPFVNRISGALLVVVGLYVGYYGLYELRLIAGVGANPQDAVIAAAGRLQGALAGWVNQHGAWPWAVLLVVLVVGAFAGTWFRRVRR
Atome Classification :
(20 SA)
-----------------------------.........10.....-----...20---------....-.....30........40........50---.........60.-....------------------------...70........80...-.....90........-100.-.....---.110.....---.----.120..-...--....130.......140.------......150....-------...160.------......170-------------------...-.....180.--.......190.......200-------...------------..-....210-----........220---------......--..--.230..---..-...240....----..------------------------.250.......260------------...--------.....------270..---.....280.....-----------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------MNE
A
L
I
G
L
A
F
A
A
G
L
V
A
-----ALNP----------
C
G
F
A
-
M
L
P
A
Y
L
L
L
V
V
YGQDSAGRTG
P
L
S
A
V
G
----
R
A
A
A
A
T
V
G
M
A
L
G
-
F
L
T
V
------------------------
F
G
I
F
G
A
L
T
I
S
A
A
T
A
V
Q
R
Y-L
P
Y
A
T
V
L
I
G
L
A
L
I
A
L-G
G
W
L
-
L
LGRG---LTALTPRSL---G----
V
R
--
W
A
-
P
T
V
--
R
LG
S
M
YGY
G
I
S
Y
A
V
A
S
LS------CTIG
P
F
L
A
V
TGAG-------LRG
G
S
V
V
------
G
S
V
A
I
Y
L
A
--------------------
Y
V
A
-
G
L
T
L
V
V
G
-
V
--
L
A
V
A
A
A
T
A
S
S
A
L
A
D
R
L
R
R
---------
I
L
P
------------
F
V
-
N
R
IS
G
A
------
L
L
V
V
V
G
L
Y
V
-----------
G
Y
Y
G
L
Y
--
E
L
--
R
L
I
AGV---GA-NP
Q
D
A
V
I
A
A
A
----
G
R
------------------------
L
Q
G
A
L
A
G
W
V
NQHG-------------A
W
P
--------
W
A
V
L
L
------
V
V
L
V
V
---
G
A
F
A
G
T
W
F
R
R
VRR-----------------------------------------------------------
23
Fugue
85.86
22%
-154
* C4 *
3FHC
-
NU214_HUMAN
A:
[9-405]
-I
P
E
R
E
M
KDFQFRA
L
K
K
V
R
IFDSPEELPK
E
R
S
S
L
L
A
V
S
N
K
Y
G
L
V
F
-----
A
G
G
A
----------
S
G
L
Q
-
I
F
P
T
K
N
L
L
I
----
Q
N
K
P
G
D
D
P
N
K
I
V
D
----
K
V
Q
G
L
L
V
P
M
K
F
P
-
I
H
H
L
------------------------
A
L
S
C
D
N
L
T
L
S
A
C
M
M
S
S
----
E
Y
G
S
I
I
A
F
F
D
V
R
T
F
S
N
E
A
Q
-
K
R
P
F
A
---
Y
H
K
L
L
K
D
A
G
---
G
MVI
D
M
K
--
W
N
-
P
T
V
PS
M
V
A
V
C
L
A
D
G
-
S
I
A
V
L
Q
V
T
E
T
V
K
V
C
A
T
L
P
S
T
V
A
V
T
S
V
C
W
S
PKGK
Q
L
A
V
G
K
Q
N
------
G
T
V
V
Q
Y
L
P
TLQEK
K
V
I
P
CPPFYESD
H
P
V
R
V
L
-
D
V
L
W
I
G
T
Y
V
--
F
A
I
V
Y
A
A
A
D
G
T
L
E
T
S
P
D
V
---------
V
M
A
L
L
P
KKEEK
H
P
E
I
F
V
-
N
F
M
E
P
C
------
Y
G
S
C
T
E
R
Q
H
-----------
H
Y
Y
L
S
Y
I
E
E
W
--
D
L
V
L
A
A
---
S
A
-
A
S
T
E
V
S
I
L
A
R
----
Q
S
------------------------
D
Q
I
N
W
E
S
W
L
L
E
D
S
SRA
E
L
P
V
T
DKS
D
D
S
L
P
--------
M
G
V
V
V
D
YTNA
P
V
L
M
L
L
S
TD
G
V
L
C
P
F
Y
M
I
N
--------------------------------------------------------------
28
Fugue
78.93
20%
-133
- C3 -
4MB0
-
?
A:
[9-261]
-----------------------PR
Y
W
S
L
Y
Y
R
E
K
I
I
E
G
M
E
K
G
M
T
A
-----
K
A
G
L
----------
I
A
H
G
-
R
G
E
A
F
D
Y
L
I
-----
G
E
R
T
I
E
P
A
E
R
A
M
----
R
A
A
V
A
K
L
L
L
A
E
N
P
V
V
S
V
------------------------
N
G
N
V
A
A
L
V
P
K
E
T
I
E
L
A
R
A
-
L
N
-
A
K
L
E
I
N
L
F
Y
R
T
E
-
D
R
V
K
-
A
I
A
E
E
---
L
R
K
Y
D
P
E
I
------------------------
E
L
L
G
I
N
P
T
K
R
I
P
G
L
E
------
H
E
R
G
---
K
V
D
E
N
G
-------
I
W
K
A
D
V
V
V
V
P
LED
G
D
R
T
E
A
L
V
--------------------
R
M
G
-
K
F
V
I
T
I
D
-
L
NP
L
S
R
S
A
R
M
A
D
I
T
I
V
D
N
I
V
R
---------
A
Y
P
------------
R
M
-
T
E
L
A
R
E
------
M
K
-------------------
D
Y
S
R
G
--
E
L
--
I
R
I
I
E
E
YD
N
G
K
-
T
L
N
D
V
L
L
H
I
R
----
D
R
------------------------
L
T
K
L
A
E
G
-----------------------------------------------------
G
I
W
R
K
K
Q
L
D
-----------------------------------------------------------
26
Fugue
75.60
18%
-123
- C3 -
3BPT
2
HIBCH_HUMAN
A:
[2-363]
--------------------------TDA
A
E
E
V
L
L
G
K
K
G
C
T
G
V
I
T
LNRPK
F
L
N
A
----------
L
T
L
N
M
I
R
Q
I
Y
P
Q
L
K
K
W
E
Q
D
P
E
T
F
L
I
I
I
K
G
A
G
----
G
K
A
F
C
A
G
G
D
I
R
V
-
I
S
E
A
------------------------
E
K
--
A
K
Q
K
I
A
P
V
F
F
R
E
E
Y
M
L
N
N
A
V
G
S
C
Q
K
P
Y
V
A
L
I
H
G
I
T
M
G
G
G
V
G
---
L
S
V
H
G
Q
F
R
V
A
T
E
K
----
C
L
--
F
A
M
P
E
T
--
A
I
G
L
F
P
D
V
G
G
G
Y
F
L
P
R
L
Q
------
G
K
L
G
Y
F
L
A
L
T
G
F
R
-------
L
K
G
R
D
V
Y
R
A
GI--
A
T
H
F
V
D
S
E
--------------------
K
L
A
M
L
E
E
D
L
L
A
-
L
--
K
S
P
S
K
E
N
I
A
S
V
L
E
N
Y
H
T
E
SKIDRDKSF
I
L
E
------------
E
H
M
D
K
I
N
S
C
F
SANT-
V
E
E
I
I
E
N
L
Q
-----------
Q
D
G
S
S
F
--
A
L
--
E
Q
L
K
V
I
---
N
K
M
S
P
T
S
L
K
I
T
L
R
Q
L
M
E
G
S
SKT
L
Q
E
V
L
T
M
E
Y
R
L
S
Q
A
C
M
R
GH
D
F
H
E
G
V
R
A
V
L
I
D
K
D
Q
-------------
S
P
K
--------
W
K
P
A
D
------
L
K
E
V
T
---
E
E
D
L
N
N
H
F
K
S
L
G
S
SDLKFAENLYFQ-----------------------------------------------
22
Fugue
65.96
20%
-136
- C5 -
4P0G
9
MLTF_PSEAE
A:
[7-435]
APT
A
L
E
R
V
Q
K
E
G
V
L
R
V
I
T
R
NSPA
T
Y
F
Q
D
R
N
G
E
T
G
F
E
Y
E
L
A
K
R
F
A
E
-----
R
L
G
-----------
V
E
L
K
-
I
E
T
A
D
N
L
D
D
L
Y
A
Q
L
S
R
E
G
G
P
A
L
A
A
A
G
L
T
P
G
R
E
D
D
A
S
V
R
Y
S
H
T
-
Y
L
D
V
T
P
Q
I
I
Y
R
N
GQQRPTRPEDLVGKR
I
M
V
L
K
G
S
S
H
A
E
Q
L
A
E
L
K
K
Q
-
Y
P
E
L
K
Y
E
E
S
D
A
V
E
V
V
-
D
L
L
R
-
M
V
D
V
G
DID
L
T
L
V
D
S
N
E
L
---
A
----
M
N
QV
Y
F
-
P
N
V
--
R
V
A
F
D
F
G
E
A
R
G
L
A
W
A
L
P
G
------
G
D
D
D
S
L
M
N
E
V
N
A
F
-------
L
D
Q
A
K
K
E
------
G
L
L
Q
R
L
K
D
--------------------
R
Y
Y
-
G
H
V
D
V
L
G
-----
Y
V
G
A
Y
T
F
A
Q
H
L
Q
Q
R
L
P
R
---------
Y
E
S
------------
H
F
-
K
Q
S
G
K
Q
L
DTD
W
R
L
L
A
A
I
G
Y
Q
E
SLWQPGATSKT
G
V
R
G
L
M
--
M
L
T
N
R
T
A
Q
A
M
---
G
V
-
S
N
R
---
L
D
P
K
----
Q
S
------------------------
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
-------------
E
L
P
ESIKE
P
D
R
S
W
F
A
L
------
A
A
Y
N
I
---
G
G
A
H
L
E
D
A
R
K
M
A
E
K
E
GLNPNK
W
L
D
V
K
K
M
LPRLAQKQWYAKTRYGYAR
G
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
W
V
T
Q
P
Q
30
Fugue
61.12
19%
-137
- C3 -
3RLB
8
?
A:
[17-192]
-----------------------------
N
V
R
L
L
T
E
I
A
F
M
A
A
L
A
F
-----
I
I
S
L
IPNTVYGWII
V
E
I
A
-
C
I
P
I
L
L
L
S
L
R
R
G
------------------
L
T
A
G
L
V
G
G
L
I
W
G
-
I
L
S
M
------------------------
I
----
T
G
H
A
Y
I
L
S
L
S
Q
A
F
-
L
E
Y
L
---
V
A
P
V
S
L
G
I
-
A
G
L
F
-
R
Q
K
T
A
---
P
L
K
L
A
P
V
L
L
---
G
----
T
F
--
V
A
-
V
L
L
--
K
Y
F
F
H
F
I
A
G
I
I
F
-----------------
W
S
Q
Y
A
W
K
G
-------
W
--
G
A
V
A
------
Y
S
L
A
V
N
G
I
--------------------
S
G
I
-
L
T
A
I
A
A
F
-
V
--
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
47.59
31%
-15
* C7 *
3MIU
5
?
B:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
47.08
31%
-20
- C7 -
3MIT
6
?
A:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.49
31%
-18
- C7 -
3MIU
5
?
A:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.17
32%
-50
- C7 -
4PIK
2
?
A:
[29-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
G
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
Y
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
A
G
E
V
A
N
Y
H
G
-------------
A
-----------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.94
32%
-50
- C7 -
4PIF
1
?
A:
[29-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
G
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
Y
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
A
G
E
V
A
N
Y
H
G
-------------
A
-----------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
45.74
32%
-31
- C7 -
2BMY
2
?
A:
[29-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
G
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
Y
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
A
G
E
V
A
N
Y
H
G
-------------
A
-----------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.53
31%
-27
- C7 -
1X1V
7
?
A:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
45.44
31%
-33
- C7 -
3MIV
-
?
A:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
45.14
32%
-27
- C7 -
2BN0
3
?
A:
[29-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
G
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
Y
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
A
G
E
V
A
N
Y
H
G
-------------
A
-----------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
45.11
32%
-31
- C7 -
2BMZ
4
?
A:
[29-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
G
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
Y
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
A
G
E
V
A
N
Y
H
G
-------------
A
-----------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
45.08
31%
-24
- C7 -
3MIT
5
?
B:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
44.93
31%
-17
- C7 -
3MIV
1
?
B:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
43.52
31%
-28
- C7 -
1X1V
5
?
B:
[29-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
K
I
F
S
G
D
------
V
V
D
A
V
D
V
T
F
-----------
T
Y
Y
G
K
T
--
E
T
--
R
H
F
G
G
S
---
G
G
-
T
P
H
E
I
V
L
Q
E
G
----
E
Y
------------------------
L
V
G
M
K
G
E
F
G
N
Y
H
G
-------------------------------------------------------------------------------------------------------------------
25
Fugue
36.89
23%
96
- C5 -
1DTC
-
?
?:
[1-26]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Q
D
I
I
S
T
I
G
D
L
V
K
W
---------
I
I
D
------------
T
V
-
N
K
F
T
K
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
35.95
41%
80
- C5 -
3O8J
-
PRPC_SALTY
A:
[225-255]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
I
A
G
T
---
G
S
-
D
V
Y
S
A
I
I
G
A
I
----
G
A
------------------------
L
R
G
P
K
H
G
G
A
N
E
---------------------------------------------------------------------------------------------------------------------