@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3101c: (2016-05-16 )
MRFGFLLNEVLTGFRRNVTMTIAMILTTAISVGLFGGGMLVVRLADSSRAIYLDRVESQVFLTEDVSANDSSCDTTACKALREKIETRSDVKAVRFLNRQQAYDDAIRKFPQFKDVAGKDSFPASFIVKLENPEQHKDFDTAMKGQPGVLDVLNQKELIDRLFAVLDGLSNAAFAVALVQAIGAILLIANMVQVAAYTRRTEIGIMRLVGASRWYTQLPFLVEAMLAATMGVGIAVAGLMVVRALFLENALNQFYQANLIAKVDYADILFITPWLLLLGVAMSGLTAYLTLRLYVRR
Atome Classification :
(20 SA)
------.........-----------10...------------.....20.-.......30...------.---....----------40.....---...50..--.....--.60........-70-.........80.........90.......---------------.100.......110....-....120.....-..130-.......140..-...-..--150.....-..160.....---..170----.......180----------..---.-......190.......200.......210.-..-...----..220......-.230.......240...---------------....--------250...-..--..260.-.....-----------------.270.......280.......290---------------......----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------M
R
F
G
F
L
L
N
E
-----------
V
L
T
G
F------------RRN
V
T
M
T
I
-
A
M
I
L
T
T
A
I
S
V
G
L------F---GG
G
M
----------
L
V
V
R
LAD---SS
R
A
I
Y
L
--DRVE
S
--
Q
V
F
L
TEDVSAN-D--SSC
D
T
T
A
C
K
A
-
L
R
E
K
I
ETR
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
KF-P
Q
F
KD-VAGKDSFP
A
S
F
I
-
V
KLE
N
-
P
E
QHK
D
F
D
T
AMK-GQP-
G
V
--
L
D
V
L
N
Q
K
E
-
L
I
D
R
L
F
A
V
L
D
---GLS
N
A
----
A
F
A
V
A
L
V
Q
------------
A
I
---
G
-
A
I
L
L
I
A
N
M
V
Q
V
A
A
Y
TRRTEI
G
I
M
R
L
VGA-
S
-
R
W
-
Y
TQ----
L
P
F
L
V
E
A
M
L
A
A
-
T
M
G
V
G
I
A
V
A
G
L
M
V
V
R
A
L
---------------
F
L
E
N
--------
A
L
N
Q
F
Y
-
Q
A--N
L
I
A
KV-DYA
D
I
-----------------
L
F
I
T
P
W
L
L
L
L
G
V
A
M
S
G
L
T
A
Y
L
T
-
L
---------------
R
L
Y
V
RR----------------------------------------
17
Fugue
88.21
100%
-68
- C2 -
4N8N
1
FTSX_MYCTU
A:
[11-112]
--------------------------------------------------------------------------------------------------------
L
--
D
R
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.21
100%
-68
- C2 -
4N8N
1
FTSX_MYCTU
A:
[11-112]
--------------------------------------------------------------------------------------------------------
L
--
D
R
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
88.01
99%
-68
- C2 -
4N8N
1
FTSX_MYCTU
A:
[11-112]
--------------------------------------------------------------------------------------------------------
L
--
D
R
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_CBE
87.95
100%
-61
- C2 -
4N8N
1
FTSX_MYCTU
B:
[10-112]
-------------------------------------------------------------------------------------------------------
Y
L
--
D
R
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.36
100%
-59
- C2 -
4N8O
5
FTSX_MYCTU
A:
[14-112]
-------------------------------------------------------------------------------------------------------------
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_CBE
86.67
100%
-55
- C2 -
4N8O
5
FTSX_MYCTU
B:
[14-112]
-------------------------------------------------------------------------------------------------------------
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_CBE
86.58
100%
-52
- C2 -
4N8N
1
FTSX_MYCTU
D:
[14-112]
-------------------------------------------------------------------------------------------------------------
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_CBE
86.52
100%
-53
- C2 -
4N8N
1
FTSX_MYCTU
C:
[14-112]
-------------------------------------------------------------------------------------------------------------
V
E
S
--
Q
V
F
L
T
E
D
V
S
A
N
-
D
--
S
S
C
D
T
T
A
C
K
A
-
L
R
E
K
I
E
T
R
S
D
V
K
A
V
R
F
L
N
---------------
R
Q
Q
A
Y
D
D
A
I
R
K
F
-
P
Q
F
K
D
-
V
A
G
K
D
S
F
P
A
S
F
I
-
V
K
L
E
N
-
P
E
Q
H
K
D
F
D
T
A
M
K
-
G
Q
P
-
G
V
--
L
D
V
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
72.86
15%
-105
- C2 -
4TXA
2
RC3H1_MOUSE
A:
[6-399]
PQWTDF
L
S
C
P
I
C
T
Q
T
-----------
F
D
E
T
I
------------
R
K
P
I
S
L
G
C
-
G
H
T
V
C
K
M
C
L
N
K
L
HRKACP
F
---
D
Q
T
T
----------
I
N
T
D
I
E
L
---
L
P
V
N
S
A
L
--
L
Q
L
V
G
--
L
C
S
G
V
E
D
T
K
H
Y
-
E
E
A
K
K
C
V
E
E
L
A
L
Y
-
L
K
P
V
L
S
R
P
M
Q
R
K
L
V
T
L
V
H
---------------
C
Q
L
V
E
E
E
G
R
I
R
A
-
M
R
A
A
R
-
S
L
G
E
R
T
V
-
T
E
L
I
-
L
Q
H
Q
N
-
P
Q
Q
L
S
S
N
L
W
A
A
V
-
R
A
R
-
G
C
QF
L
G
P
A
R
Q
E
E
-
A
L
K
L
V
L
L
A
L
E
DG
S
A
L
S
R
K
----
V
L
V
L
F
V
V
Q
R
LEPRFPQAS
K
T
S
I
---
G
-
H
V
V
Q
L
L
Y
R
A
S
C
F
K
V
T
K
R
D
S
-
S
L
M
Q
L
K
E
E
-
F
-
R
T
-
Y
E
A
----
L
R
R
E
H
D
S
Q
I
V
Q
I
A
M
E
A
G
L
R
I
A
P
D
Q
W
S
S
L
L
---------------
Y
G
D
Q
--------
S
-
H
K
S
H
-
M
Q
--
S
I
I
D
K
L
-
Q
T
P
A
S
-----------------
F
A
Q
S
V
Q
E
L
T
I
A
L
Q
R
T
G
D
P
A
N
L
N
R
L
---------------
R
P
H
L
E
L
L
A
N
IDPSPDAPPPT
W
E
Q
L
E
N
G
L
V
A
V
R
T
V
V
H
G
L
V
D
Y
I
Q
NHS
21
Fugue
52.98
18%
-69
- C2 -
3G3L
10
?
A:
[10-305]
-PA
E
A
K
Y
Y
I
A
G
T
I
T
D
-----------
A
T
T
G
Q
E-----------
L
T
T
A
K
V
T
L
G
D
K
S
V
T
S
S
F
N
E
Q
V
------
N
YKA
E
G
Y
A
----------
L
V
V
S
A
D
G
Y
Y
P
V
K
R
Q
V
Y
L
--
N
Q
V
S
D
G
Q
T
S
V
A
T
V
N
V
A
L
V
-
S
--
V
E
A
A
V
I
P
P
V
V
-
P
P
T
D
P
E
T
D
I
N
E
G
E
A
T
K
V
----------------
A
D
K
A
V
E
V
A
K
P
S
E
-
S
T
V
T
D
M
L
A
G
T
T
A
-----------
T
-
P
E
E
K
K
A
L
D
E
T
L
E
M
A
G
G
M
K
V
--
G
E
T
-
T
P
E
V
-
L
A
D
---
G
S
I
L
---
A
I
T
P
V
----
K
F
T
N
P
I
Q
D
------------
A
P
---
A
M
V
P
Y
F
Y
N
E
G
C
E
L
T
G
D
V
K
E
---------------------------------------
V
A
A
P
V
A
V
A
A
D
I
Q
K
A
---------------
F
L
S
N
--------
A
A
K
A
L
N
M
N
A
--
G
F
V
Q
K
I
-
G
Y
T
R
I
-----------------
S
V
L
N
G
Y
S
I
L
-
G
Y
T
I
K
G
Q
L
V
S
K
K
-
L
---------------
T
F
L
I
S
G
K
Y
Y
E
G
I
V
S
Y
Q
K
S
V
M
I
Y
P
N
Y
Y
S-------------------
25
Fugue
49.53
17%
-89
- C1 -
4L8N
3
?
A:
[6-457]
--N
T
S
I
C
R
L
G
F
T
Y
D
I
SQSKNWGNNKP
V
I
K
S
I
I
P
YS
S
A
E
Q
A
GIK
K
Y
D
V
I
E
E
I
-
N
G
V
P
V
T
E
V
S
V
D
E
------
I
---
P
Q
L
L
N
PAGRN
D
V
L
L
T
I
S
N
L
S
S
---
P
S
K
Q
V
L
V
K
K
D
C
K
K
S
--
N
A
I
T
E
D
Q
L
A
S
A
Y
A
M-
Y
S
L
E
T
T
N
E
Q
E
-
F
V
C
P
F
K
T
T
V
T
S
D
G
V
D
F
G
N
FK
T
F
A
F
S
T
IDENN
R
K
L
E
T
V
I
N
E
C
I
E
N
E
-
L
T
K
K
G
-
L
T
V
D
I
A
K
P
D
L
L
I
-
Q
T
F
Y
F
-
F
D
K
N
P
N
Y
L
G
A
N
E
-
K
E
P
-
T
Y
--
R
Y
N
F
S
H
S
K
M
E
K
F
P
F
L
N
Y
A
A
---
A
E
A
E
A
E
Y
L
L
Q
F
G
I
R
I
I
D
------------
Q
K
DIP
G
-
R
V
L
W
E
C
E
A
N
E
L
L
E
D
S
Y
R
L
D
E
Y
A
R
V
H
V
P
L
M
C
M
Q
Y
P
Y
T
K
YG
R
N
V
P
F
K
V
S
K
K
T
Y
N
-
Y
T
G
I
S
Y
D
I
D
K
L
D
Q
V
V
D
V
DRNS
P
A
Y
A
A
GIRPRD
I
I
E
K
IGRHKMDH
S
A
E
E
F
S
-
S
A
Y
K
R
F
I
T
N
T
M
Q
Y
R
D
P
KT
M
F
T
D
ANGFK
Y
C
M
F
W
D
V
F
K
Y
P
Q
I
A
D
A
S
Q
S
S
D
Y
L
P
A
F
S
Y
-
L
YYFAPYINPSGNN
A
C
T
F
N
I
K
R
GK
T
K
L
E
V
I
I
R
P
T
I
R
S
E
V
T
V
E
IK------------------
26
Fugue
36.88
12%
58
- C2 -
1OKS
1
A:
[2-54]
---------------------------------------------------------------------------------------------------------------------------------------------------
A
S
R
S
V
I
R
S
I
I
K
---------------
S
S
R
L
E
E
D
R
K
R
Y
L
M
T
L
L
D
D
-
I
K
G
A
N
D
L
A
K
F
H
Q
M
L
V
K
I
I
M
K
H
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
35.06
16%
62
- C2 -
1Z0P
-
?
A:
[1-77]
--------------------------------------------------------------------------------------------------------
M
--
S
Y
E
K
E
--
F
L
K
D
F
E
D
W
V
K
T
-
Q
--
I
Q
V
N
Q
L
A
M
A
T
-
S
Q
E
V
A
D
E
R
A
K
D
A
F
I
R
Y
E
S
---------------
K
L
D
A
Y
E
F
L
L
G
K
F
-
D
N
Y
K
N
-
G
K
A
F
H
D
I
P
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
33.69
21%
171
- C2 -
2RU9
-
?
A:
[22-45]
-----------------------------------------------------------------------------------------------------------------------------------------
E
A
-
L
K
V
R
L
L
E
T
E
G
V
K
E
V
L
I
A
E
---------------
E
E
H
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
33.36
19%
127
- C2 -
1CW5
-
CBB2_CARML
A:
[1-48]
------------------------------------------------------------------------------------------------------------------------
V
N
Y
G
N
-
G
--
V
S
C
S
K
T
K
C
S
V
N
W
G
Q
A
F
Q
E
R
Y
T
A
G
I
N
S
F
V
S
---------------
G
V
A
S
G
A
G
S
I
G
R
R
-
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
32.25
20%
229
- C2 -
3NE5
-
CUSA_ECOLI
A:
[65-96]
---------------------------------------------------------------------------------------------------------------------------------------
V
T
Y
P
-
L
T
T
T
M
L
S
V
P
G
A
K
T
V
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
32.17
21%
180
- C2 -
4Q2L
3
?
A:
[25-48]
-----------------------------------------------------------------------------------------------------------------------------------------
E
A
-
L
K
V
R
L
L
E
T
E
G
V
K
E
V
L
I
A
E
---------------
E
E
H
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
30.65
7%
125
- C2 -
1A02
2
F:
[3-55]
-----------------------------------------------------------------------------------------------------------------------
R
R
I
R
R
E
-
R
--
N
K
M
A
A
A
K
S
R
N
-
R
R
R
E
L
T
D
T
L
Q
A
E
T
D
Q
L
E
D
---------------
E
K
S
A
L
Q
T
E
I
A
N
L
-
L
K
E
K
E
-
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
29.00
30%
301
* C2 *
2YKA
-
B:
[1-23]
--------------------------------------------------------------------------------------------------------------------------
G
P
L
-
G
--
S
S
C
K
T
S
W
A
D
R
-
V
R
E
A
A
A
Q
R
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
28.40
0%
223
- C2 -
3W9I
-
MEXB_PSEAE
A:
[61-93]
---------------------------------------------------------------------------------------------------------------------------------------
V
V
Q
V
-
I
E
Q
Q
M
N
G
I
D
N
L
R
Y
I
S
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------