@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3262: (2016-05-18 )
MTGPEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLRDGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDRTLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLGVTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTEVAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLFWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPAADLLILK
Atome Classification :
(20 SA)
.........10......-..20........30........40........50........60....-....70..-----------......80........90.---------.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200......-.210........220........230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330...-....-----340.......350.......360.......370.......380.......390.......400...-.--...---410.......420.......430..--.....440......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTGPEHGSA
S
T
I
E
I
L
PV-IGLPEFRPG
D
D
L
S
A
A
V
A
A
AAPWLRDG
D
V
V
V
V
T
S
K
V
V
S
KCE
G
R
LVPAPE-D
P
E
Q
R
D
R
L
-----------
R
R
K
L
I
E
D
E
A
V
R
V
L
A
RKD
R
T
---------
L
ITENRL
G
L
V
Q
A
AAGVDGSNVGRS
E
L
A
L
L
PVDPDA
S
A
A
T
L
R
A
G
L
R
E
RL
G
V
T
V
A
V
V
I
TDTMGRAWRNGQTD
A
A
V
G
A
A
G
L
A
V
L
R
N
YAGVRDPYGN
E
L
V
V
T
E
V
A
V
A
D
E
I
A
A
A
A
D
L
VKGK-LT-ATPV
A
V
V
RGFG-VSDD
G
S
T
A
R
Q
L
LRPGAN
D
L
F
W
LG
T
A
E
A
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
FSTDPV
P
G
D
L
V
E
A
A
V
A
E
A
LTAPAPHHTRP
T
R
F
V
W
L
QT
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
SDLTSDGL
P
A
D
A
I
E
R
R
V-ARG
Q
-----
I
L
YDAP
E
V
V
I
P
M
LVPDGAHSYPDAARTDAE
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
WIG
S
T
I
F
A
A
-
D
--
L
V
R
---DELDLPVDWEPL
G
A
I
A
I
GYADEPSG--LRDPVPAA
D
L
L
I
LK
1
PsiBlast_PDB
94.74
100%
-121
- C5 -
4XOM
1
?
A:
[4-207]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
E
A
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
23
PsiBlast_CBE
94.61
100%
-123
- C5 -
4XOQ
4
?
B:
[4-207]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
E
A
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
26
PsiBlast_CBE
94.43
100%
-117
- C5 -
4XOO
2
?
B:
[7-207]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
25
PsiBlast_CBE
94.20
100%
-116
- C5 -
4XOO
2
?
C:
[8-207]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
---
R
D
P
V
P
A
A
D
L
L
I
L
K
29
PsiBlast_CBE
94.02
100%
-117
- C5 -
4XOM
1
?
B:
[4-207]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
E
A
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
3
PsiBlast_PDB
93.60
100%
-118
- C5 -
4XOQ
3
?
A:
[4-207]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
E
A
L
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
2
PsiBlast_PDB
93.46
100%
-118
- C5 -
4XOO
2
?
A:
[12-207]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
22
PsiBlast_CBE
92.99
100%
-117
- C5 -
4XOQ
3
?
C:
[11-207]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
A
A
D
L
L
I
L
K
28
PsiBlast_CBE
91.18
100%
-119
- C5 -
4XOM
1
?
C:
[13-207]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
----
L
R
D
P
V
P
A
A
D
L
L
I
L
K
21
PsiBlast_CBE
91.10
100%
-114
- C5 -
4XOQ
3
?
D:
[9-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
--
L
R
D
P
V
P
-
A
D
L
L
I
L
K
24
PsiBlast_CBE
89.44
100%
-116
- C5 -
4XOO
2
?
D:
[10-207]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
------------
D
L
L
I
L
K
27
PsiBlast_CBE
89.41
100%
-122
- C5 -
4XOM
1
?
D:
[18-207]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
--------------
L
L
I
L
K
33
HHSearch
88.85
95%
-120
- C5 -
4XOM
1
?
A:
[12-204]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
Q
A
Q
L
L
R
R
S
V
R
R
F
S
T
D
P
V
P
G
D
L
V
E
A
A
V
A
E
A
L
T
A
P
A
P
H
H
T
R
P
T
R
F
V
W
L
Q
T
P
A
I
R
A
R
L
L
D
R
M
K
D
K
W
R
S
D
L
T
S
D
G
L
P
A
D
A
I
E
R
R
V
-
A
R
G
Q
-----
I
L
Y
D
A
P
E
V
V
I
P
M
L
V
P
D
G
A
H
S
Y
P
D
A
A
R
T
D
A
E
H
T
M
F
T
V
A
V
G
A
A
V
Q
A
L
L
V
A
L
A
V
R
G
L
G
S
C
W
I
G
S
T
I
F
A
A
-
D
--
L
V
R
---
D
E
L
D
L
P
V
D
W
E
P
L
G
A
I
A
I
G
Y
A
D
E
P
S
G
---
L
R
D
P
V
P
A
A
D
L
L
--
30
PsiBlast_CBE
59.61
39%
-72
* C6 *
2PHN
8
COFE_ARCFU
B:
[6-231]
-----------
V
E
V
F
P
V
-
E
G
L
P
L
I
K
E
G
D
D
L
A
E
L
I
S
S
R
V
R
F
-
E
D
G
D
V
L
V
V
C
S
T
V
I
S
K
A
E
G
R
I
R
R
L
E
E
F
N
P
S
E
R
A
K
E
-----------
I
A
A
R
I
G
K
P
A
E
F
V
Q
A
V
L
E
E
S
EEVLLDFP
F
L
L
V
K
A
K
F
G
N
V
C
V
N
A
G
I
D
A
S
N
V
E
E
G
S
L
L
L
P
P
L
D
P
D
G
S
A
E
K
L
R
R
R
I
L
E
L
T
G
K
R
V
G
V
I
I
T
D
T
N
G
R
C
F
R
R
G
V
V
G
F
A
I
G
I
S
G
V
K
A
M
K
D
W
I
G
R
K
D
L
Y
G
R
E
L
E
V
T
V
E
C
V
A
D
E
I
A
A
F
A
N
L
L
M
G
E
G
G
D
-
G
I
P
A
V
V
V
R
G
L
N
-
V
A
G
E
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.94
39%
-68
- C6 -
2PHN
12
COFE_ARCFU
A:
[6-231]
-----------
V
E
V
F
P
V
-
E
G
L
P
L
I
K
E
G
D
D
L
A
E
L
I
S
S
R
V
R
F
-
E
D
G
D
V
L
V
V
C
S
T
V
I
S
K
A
E
G
R
I
R
R
L
E
E
F
N
P
S
E
R
A
K
E
-----------
I
A
A
R
I
G
K
P
A
E
F
V
Q
A
V
L
E
E
S
EEVLLDFP
F
L
L
V
K
A
K
F
G
N
V
C
V
N
A
G
I
D
A
S
N
V
E
E
G
S
L
L
L
P
P
L
D
P
D
G
S
A
E
K
L
R
R
R
I
L
E
L
T
G
K
R
V
G
V
I
I
T
D
T
N
G
R
C
F
R
R
G
V
V
G
F
A
I
G
I
S
G
V
K
A
M
K
D
W
I
G
R
K
D
L
Y
G
R
E
L
E
V
T
V
E
C
V
A
D
E
I
A
A
F
A
N
L
L
M
G
E
G
G
D
-
G
I
P
A
V
V
V
R
G
L
N
-
V
A
G
E
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
58.46
36%
-72
- C6 -
2PHN
12
COFE_ARCFU
A:
[5-248]
----------
R
V
E
V
F
P
V
E
G
L
-
P
L
I
K
E
G
D
D
L
A
E
L
I
S
S
R
-
V
R
F
E
D
G
D
V
L
V
V
C
S
T
V
I
S
K
A
E
G
R
I
R
R
L
E
E
-
F
N
P
S
E
R
A
K
E
I
A
A
R
I
GKP
A
E
F
V
Q
A
V
L
E
E
S
E
E
V
L
L
D
F
P
F
L
---------
L
V
K
-
A
K
F
G
N
V
C
V
N
A
G
I
D
A
S
N
V
E
E
G
S
L
L
L
P
P
L
D
P
D
G
S
A
E
K
L
R
R
R
I
L
E
L
T
G
K
R
V
G
V
I
I
T
D
T
N
G
R
C
F
R
R
G
V
V
G
F
A
I
G
I
S
G
V
K
A
M
K
D
W
I
G
R
K
D
L
Y
G
R
E
L
E
V
T
V
E
C
V
A
D
E
I
A
A
F
A
N
L
L
M
G
E
-
G
G
D
G
I
P
A
V
V
V
R
G
L
N
V
A
--
G
E
G
S
M
E
E
I
Y
R
S
E
E
E
D
V
I
R
R
C
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
57.73
21%
-103
- C5 -
3GE5
10
?
A:
[26-193]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
R
L
I
----
E
D
F
F
R
T
R
R
S
V
R
K
F
I
D
R
P
V
E
E
E
K
L
M
A
I
L
E
A
G
R
I
A
P
S
A
H
N
Y
Q
P
W
H
F
L
V
V
R
E
E
E
G
R
K
R
L
A
P
C
S
------------------------
Q
Q
P
-----
W
F
P
G
A
P
I
Y
I
I
T
L
G
D
H
Q
R
A
W
K
R
-------
G
A
G
D
S
V
D
I
D
T
S
I
A
M
T
Y
M
M
L
E
A
H
S
L
G
L
G
C
T
W
V
C
A
--
F
D
Q
-
A
--
L
C
S
---
E
I
F
D
I
P
S
H
M
T
P
V
S
I
L
A
L
G
Y
G
D
P
T
V
P
PR
E
A
F
N
R
K
T
I
E
E
V
V
--
12
PsiBlast_PDB
57.40
25%
-93
- C5 -
4DN2
2
?
A:
[17-183]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
Y
F
-
Q
S
M
E
T
L
E
A
I
R
T
-----
R
R
S
V
R
K
F
S
D
R
P
V
E
P
E
K
L
R
A
V
L
D
A
A
R
L
A
P
S
W
A
N
M
Q
C
W
R
F
V
V
V
E
D
Q
A
T
K
V
Q
I
S
E
L
--
S
Y
V
E
A
Y
F
G
P
K
G
Y
K
S
N
P
A
Q
K
A
L
-
A
-----------
E
A
P
V
V
I
I
A
C
G
E
P
------
P
Q
S
G
E
L
R
G
Q
Q
Y
Y
L
T
-
D
V
G
I
A
A
Q
N
L
M
L
A
A
H
D
L
G
L
G
S
V
F
V
G
--
V
F
D
E
-
Q
--
Q
L
G
---
E
L
L
G
I
P
A
E
L
R
I
V
G
L
F
P
L
G
Y
----------------------
16
PsiBlast_PDB
56.88
23%
-91
- C5 -
3EK3
5
?
A:
[14-188]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
S
V
R
A
Y
D
R
K
Q
I
P
A
D
D
L
N
A
I
L
E
A
G
A
Y
A
P
S
G
M
H
Y
E
T
W
H
F
T
A
V
C
N
T
V
K
L
E
E
L
N
E
R
I
K
----------
G
A
F
A
K
S
D
D
K
H
L
R
E
R
G
H
SETYC
C
Y
Y
H
A
P
T
L
V
I
V
S
N
E
P
K
Q
W
W
A
G
M
D
C
A
--------------
C
A
I
E
N
M
F
L
A
A
T
S
L
G
I
A
S
C
W
I
N
Q
L
G
T
T
C
-
D
D
P
E
V
R
A
Y
L
T
S
L
G
V
P
E
N
H
K
V
Y
G
C
V
A
L
G
Y
K
A
E
G
A
L
--
L
K
E
K
T
V
K
A
G
T
I
T
I
-
36
HHSearch
56.35
22%
-102
- C5 -
3GB5
3
IYD1_MOUSE
A:
[53-250]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
Q
E
F
----
Y
E
L
L
N
K
R
R
S
V
R
F
I
S
S
E
H
V
P
M
E
V
I
E
N
V
I
K
A
A
G
T
A
P
S
G
A
H
T
E
P
W
T
F
V
V
V
K
D
P
D
M
K
H
K
I
R
E
I
I
E
E
E
E
E
I
-------------------
K
E
-----
Y
L
D
T
A
P
V
L
I
L
I
F
K
Q
V
-----------------
Y
N
E
I
S
V
S
I
A
C
G
L
L
L
A
A
L
Q
N
A
G
L
V
T
V
T
T
T
P
--
L
N
C
G
P
--
R
L
R
---
V
L
L
G
R
P
S
H
E
K
L
L
V
L
L
P
V
G
Y
P
S
R
D
A
T
V
-
P
D
L
K
R
K
A
L
D
Q
I
M
--