@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3294c: (2016-05-18 )
MGLPRRPCCDTTGSARYRESVRRYPRIGEDSAAYRRRLCRESAKARNVDRVVKRDAADVSNLQRIADLPRLIRLLAARSASELNLSSLATDAEIPVRTLPPYLDLLETLYLIDRIPAWSTNLSKRVVDRPKVLLLDSGLAARLVNVSPTGAGPHANPNAAGAIIETFVIAELRRQLGWSQQAPRLFHYRDRDGAEVDLILETADGLIAAIEIKSAATLRGRDTRSISRLRDKVGARFAGGVILHTGPQAQPFGDRLAAVPIDILWSPSG
Atome Classification :
(20 SA)
---------.........10........20......--------..30-----........40...--.....50...-----.....60.---.....-.-.70........--80-----........90---..-----.......---100.......110---.......120-----------........130..--------------------.....140-...---.....150.......-------160--..-----.....170--.---.---..--....180...-----------....190.......200.......-210........220-------...-.....230....--------...240.....-..250...--.....-260------........--------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------MGLPRRPCCDTTG
S
A
R
Y
R
E
S
V
R
RYPRI--------GE
D
S
-----
A
A
Y
R
R
R
L
C
R
E
S
A
K--AR
N
V
D
R
V
V
K
R-----DAA
D
V
S
N
L
---
Q
R
I
A
D
-
L
-
P
R
L
I
R
L
L
A
ARS--AS-----EL
N
L
S
SLAT----DA-----EIPVRTL---P
P
Y
L
D
L
L
E
T
L
Y
L
I
---DRIPAWST
N
------------
L
S
K
R
VVDRP
K
V
L
L
--------------------LDSG
L
A
A
--
R
L
V
---NVSPTGAGPHANPNA-------
A
G
A
--
I
I
-----
E
T
F
V
I
A
E
---
L
---
R
---
R
Q--LGWSQQA
P
R
L
-----------
F
H
Y
RDRDG
A
E
V
D
L
I
L
ETAD
G
L
I
A
A
-
I
E
-
I
K
S
A
A
TLRG-R-------DT
R
-
S
I
S
R
L
R
D
K
VGAR--------FAG
G
V
I
L
HTGP-QAQP-FGD--R
L
A
A
V
-
P
I
-------
D
I
L
WSPSG--------------------
43
Fugue
62.05
19%
-32
- C2 -
4FHL
10
YEKI_SCHPO
A:
[2-392]
G
S
M
T
L
S
S
N
Q
Y
Q
L
P
L
N
V
R
P
Y
T
T
T
W
C
S
Q
S
P
S
C
S
N
L
L
A
I
--------
G
H
D
T
G
I
T
I
Y
C
A
S
E
E
S
T
G
L
T
L
Q
E
--
L
F
T
I
Q
T
G
L
P
T
-----
L
H
L
S
F
S
S
S
---
C
S
Y
S
E
-
N
-
S
P
V
Y
S
L
F
L
A
C
V
--
C
Q
-----
D
N
T
V
R
L
I
I
T
KN--
E
T
-----
I
I
T
Q
H
V
L
G
G
K
S
G
H
H
N
F
V
N
D
I
D
I
A
---
D
V
Y
S
A
-----------------
D
N
R
L
A
E
Q
V
I
A
S
V
--------------------
G
D
D
C
T
L
I
I
W
R
L
T
---
D
E
G
P
I
L
A
G
Y
P
L
S
S
P
G
-------
I
S
V
--
Q
F
R
PSNP
N
Q
L
I
V
G
E
---
R
---
N
G
N
I
R
I
--
F
D
W
T
L
N
L
T
E
L
VKNPWL
L
T
L
N
T
L
P
L
V
N
S
S
L
A
N
V
R
W
I
G
S
D
G
S
G
I
L
A
M
-
C
---
K
S
G
A
W
L
R
W
-
N
LFKNLLP
N
V
Q
-
G
I
S
L
F
P
S
L
L
G
A
C
P
H
PRYMD
Y
F
A
T
A
H
S
Q
H
G
L
I
-
Q
L
I
N
T
Y
E
K
--
D
S
N
S
I
-
P
I
QLGMPIV
D
F
C
W
H
Q
D
G
S
H
L
A
I
A
T
EG
S
V
L
L
T
R
L
MGFT
47
Fugue
58.82
12%
-31
- C3 -
4PW8
1
T23O_HUMAN
A:
[26-367]
----I
Y
G
N
Y
L
H
L
E
K
V
L
N
A
Q
E
L
Q
S
E
T
K
G
N
K
I
H
D
E
H
L
F
--------
I
I
T
H
-----
Q
A
Y
E
L
W
F
K
Q
I
L
W
E
--
L
D
S
V
R
E
I
F
Q
N
GHVRD
E
R
N
M
L
K
V
V
---
S
R
M
H
R
-
V
-
S
V
I
L
K
L
L
V
Q
Q
F
--
S
I
L
E
T
MT
A
L
D
F
N
D
F
R
E
----
Y
L
-----
S
P
A
S
G
F
Q
---
S
L
Q
F
R
L
L
E
N
K
I
G
V
LQE
E
N
E
L
L
L
K
S
E
------------
Q
E
K
T
L
L
E
L
V
E
A
W
L
E
R
TPGLEPHGFN
F
W
G
K
L
E
K
N
I
T
R
G
L
E
E
--
E
F
I
---
R
I
Q
A
K
E
E
S
E
E
K
E
E
Q
V
-------
A
E
F
--
Q
K
-----
Q
K
E
V
L
L
S
---
L
F
D
E
K
---
R
H
--
E
H
L
L
S
K
G
E
R
R
-----------
L
S
Y
R
A
L
Q
G
A
L
M
I
Y
F
Y
R
E
E
P
R
F
Q
V
P
-
F
Q
-
L
L
T
S
L
M
D
I
D
-
S
-------
L
M
T
-
K
W
R
Y
N
H
V
C
M
V
H
R
--------
M
L
G
-------
S
-
R
Y
K
V
-
F
V
D
L
F
N
L
S
T
Y
-
L
I
-------
P
R
H
W
I
P
K
M
N-------------------
39
HHSearch
53.83
16%
-120
- C4 -
2O03
1
ZUR_MYCTU
A:
[13-66]
----------------------------------------------------------------------------------------------------
R
-
A
A
I
S
T
L
L
E
T
L
---
D
D
-----
F
R
S
A
Q
E
L
H
D
----
E
L
R
R
R
GE
N
I
G
L
T
T
V
---
Y
R
T
L
Q
S
M
A
S
S
G
L
V
---
D
T
L
H
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
52.83
20%
-136
- C4 -
2LNB
-
ZBP1_HUMAN
A:
[21-66]
----------------------------------------------------------------------------------------------------
E
-
Q
R
I
L
Q
V
L
T
E
A
---
G
S
-----
P
V
K
L
A
Q
L
V
K
----
E
C
-----
Q
A
P
K
R
E
L
---
N
Q
V
L
Y
R
M
K
K
E
L
K
V
---
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
52.11
14%
-41
- C5 -
2OC5
4
ALDEC_PROMM
A:
[21-241]
---------
E
A
L
P
D
F
T
------
S
D
R
Y
K
D
A
Y
S
R
I
N
A
I
--------
V
I
E
G
-----
E
Q
E
A
H
D
N
Y
I
A
I
G
T
--
L
L
--------------
P
D
H
V
E
E
L
---
K
R
L
A
K
M
E
M
R
H
K
K
G
F
T
A
C
G
K
--
N
---------------------------
L
G
V
E
A
D
M
--
D
F
A
R
E
F
F
A
P
L
R
D
N
---
F
Q
T
A
L
G
Q
G
K
-------------------
T
P
T
C
L
L
--------------------
I
Q
A
L
L
I
E
--
A
F
A
---
I
S
A
Y
H
T
Y
I
P
V
S
D
P
F
A
-------
R
K
I
--
T
E
-----
G
--
V
V
K
D
---
E
---
Y
---
T
H
--
L
N
Y
G
E
A
W
--
L
-----------
K
A
N
L
E
S
C
R
E
E
L
L
E
A
N
R
E
N
L
P
L
I
R
R
M
L
D
Q
V
A
G
D
A
A
V
L
Q
M
D
-------
K
E
D
-
L
I
E
D
F
L
I
A
Y
Q
E
S
--------
L
T
E
I
-----------
G
-
F
N
T
--
R
E
I
T
R
M
A
A
-------
A
A
L
-------------------------
48
Fugue
50.90
17%
-29
- C5 -
1Y08
1
?
A:
[33-323]
----T
S
V
W
T
K
G
V
T
P
-
P
A
N
F
T
Q
G
E
D
V
F
H
A
P
Y
V
A
N
Q
G
W
Y
D
I
T
K
TFN
G
K
D
D
LL
S
G
-
A
A
T
A
G
N
M
L
H
W
W
F
D
Q
N
K
D
Q
I
K
R
Y
L
E
E
-----
H
P
E
K
Q
K
I
N
F
NG
E
Q
M
F
D
-
V
-
K
E
A
I
D
T
K
N
H
Q
L
--
D
S
-----
K
L
-
F
E
Y
F
K
E
----
K
A
-----
F
P
Y
L
K
H
L
---
G
V
F
P
D
H
V
I
D
M
F
I
N
---
G
Y
R
L
S
L
T
N
H
------------
G
P
T
P
V
K
E
G
S
K
D
P
----------------------
R
G
G
I
F
D
--
A
V
F
TRG
D
Q
S
K
L
L
T
S
R
H
D
F
K
E
K
-------
N
L
K
--
E
I
-----
S
D
L
I
K
K
E
---
L
---
T
---
E
G
K
A
L
G
L
S
H
T
-
Y
R
I
-----------
N
H
V
I
N
L
W
G
A
D
F
D
-----
S
N
G
N
L
K
A
-
I
Y
-
V
T
D
S
------
D
-------
S
N
A
-
S
I
G
M
K
K
Y
F
V
G
V
N
--------
S
A
G
K
V
A
I
S
A
K
E
I
K
E
D
N
-
I
G
A
--
Q
V
L
G
L
-
F
T
L
S
TG---
Q
D
S
W
N
Q
T
N
--------------------
31
HHSearch
50.13
24%
-111
- C4 -
2PN6
-
?
A:
[6-50]
------------------------------------------------------------------------------------------------------
L
R
I
L
K
I
L
Q
Y
N
A
---------
K
Y
S
L
D
E
I
A
R
----
E
I
-----
R
I
P
K
A
T
L
---
S
Y
R
I
K
K
L
E
K
D
G
V
I
---
K
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
50.01
14%
11
- C5 -
4KE2
-
ANPM_PSEAM
A:
[0-195]
---------
M
N
I
D
--------------------
P
A
A
--------
R
A
A
A
-----
A
A
A
A
S
K
A
A
V
T
A
A
D
--
A
A
A
A
A
A
T
I
A
A
-----
S
A
A
S
V
A
A
A
---
T
A
A
D
D
-
A
-
A
A
S
I
A
T
I
N
A
A
S
--
A
A
-----
A
K
S
I
A
A
A
A
A
----
M
A
-----
A
K
D
T
A
A
A
---
A
A
S
A
A
A
A
A
V
A
S
A
A
---
K
A
L
E
--------------------------------------------------------------------
T
I
N
V
K
A
A
Y
A
A
A
T
-------
T
A
N
--
T
A
-----
A
A
A
A
A
A
T
---
A
---
T
---
T
A
--
A
A
A
A
A
A
K
A
T
I
-----------
D
N
A
A
A
A
K
A
A
A
V
A
T
A
V
S
D
A
A
A
T
A
A
T
-
A
A
-
A
V
A
A
A
T
L
E
A
-
A
-------
A
A
K
-
A
A
A
T
A
V
S
A
A
A
A
A
--------
A
A
A
A
I
A
F
A
A
A
P
------------------------------------------------------
35
HHSearch
48.42
15%
-105
* C4 *
2CYY
-
REG6_PYRHO
A:
[10-56]
------------------------------------------------------------------------------------------------------
K
K
I
I
K
I
L
Q
N
D
G
---------
K
A
P
L
R
E
I
S
K
----
I
T
-----
G
L
A
E
S
T
I
---
H
E
R
I
R
K
L
R
E
S
G
V
I
---
K
K
F
T
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
48.25
24%
-51
- C4 -
2H4R
-
SPB10_CHICK
A:
[271-401]
----------------------------------------------------------------------------------------------------
L
-
E
Q
L
E
R
E
L
T
Y
E
R
--
L
S
-----
E
W
A
D
S
K
M
M
T
E
T
LV
D
L
-----
H
L
P
K
F
S
L
---
E
D
R
I
D
L
R
D
T
L
R
N
M
---
G
M
T
T
A
F
T
T
N
------------
A
D
F
R
G
M
T
D
K
K
D
L
A
--------------------
I
S
K
V
I
H
Q
--
S
F
V
---
A
V
D
E
K
G
----
T
E
A
A
A
--------------------------------------
V
--
L
K
F
K
V
D
H
P
-------------
F
H
F
F
I
R
H
N
K
S
K
T
I
L
F
------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.15
25%
-4
- C4 -
2GBZ
1
ORN_XANCP
A:
[27-175]
--------------------------------------------------------------------------------------------------------------------
S
-----
I
I
E
I
A
T
I
V
T
----
D
A
-----
Q
L
N
V
L
A
E
---
G
P
E
L
A
I
A
H
S
L
E
T
L
---
E
A
M
D
E
W
N
R
N
------------
Q
H
R
R
-------------------------------
S
G
L
W
Q
--
R
V
L
---
D
S
Q
V
T
H
A
Q
A
E
A
Q
T
V
A
F
L
G
E
W
IR
A
G
A
S
P
M
C
-----
G
N
S
I
C
Q
D
R
R
F
L
---
H
---
R
Q
--
M
S
---
R
L
E
R
Y
-----------
F
H
Y
R
N
L
D
V
S
T
I
K
E
L
A
R
R
W
A
P
A
V
A
S
-
G
F
-
A
K
S
S
A
H
T
A
L
-
S
-------
D
V
R
D
S
I
D
E
L
R
-------------------------------------------------------------------------------
36
HHSearch
47.91
13%
-133
- C4 -
2XVC
2
?
A:
[13-58]
------------------------------------------------------------------------------------------------------
R
E
L
L
D
Y
I
V
N
N
---
G
G
-----
F
L
D
I
E
H
F
S
K
----
V
Y
-----
G
V
E
K
Q
E
V
---
V
K
L
L
E
A
L
K
N
K
G
L
I
---
A
V
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
46.08
22%
-80
- C4 -
3KE2
1
?
A:
[20-65]
-------------------------------------------------------------------------------------------------
L
R
-
K
-
L
Y
L
A
H
L
M
D
-----
D
A
-----
R
H
N
L
L
S
L
G
K
----
L
T
-----
G
M
P
R
R
T
L
---
Q
D
A
I
A
S
F
A
D
I
G
I
E
---
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
45.66
15%
-90
- C4 -
3I71
2
EUTK_ECOLI
A:
[6-51]
------------------------------------------------------------------------------------------------------
D
E
L
L
A
L
L
T
S
V
---
R
Q
-----
G
M
T
A
G
E
V
A
A
----
H
F
-----
G
W
P
L
E
K
A
---
R
N
A
L
E
Q
L
F
S
A
G
T
L
---
R
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
44.05
11%
-100
- C4 -
2QVO
-
Y1382_ARCFU
A:
[15-81]
------------------------------------------------------------------------------------------------------
L
E
I
L
M
T
I
Y
Y
E
S
L
G
G
N
-----
D
V
Y
I
Q
Y
I
A
S
----
K
V
-----
N
S
P
H
S
Y
V
---
W
L
I
I
K
K
F
E
E
A
K
M
V
---
E
C
E
L
E
---------------------
G
R
T
K
I
I
R
L
--------------------
T
D
K
G
Q
K
I
--
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
44.04
24%
-45
- C4 -
2DUT
-
SPB10_CHICK
A:
[271-401]
----------------------------------------------------------------------------------------------------
L
-
E
Q
L
E
R
E
L
T
Y
E
R
--
L
S
-----
E
W
A
D
S
K
M
M
T
E
T
LV
D
L
-----
H
L
P
K
F
S
L
---
E
D
R
I
D
L
R
D
T
L
R
N
M
---
G
M
T
T
A
F
T
T
N
------------
A
D
F
R
G
M
T
---
D
L
A
--------------------
I
S
K
V
I
H
Q
--
S
F
V
---
A
V
D
E
K
G
----
T
E
A
A
A
-------
A
T
A
--
V
I
-----
I
S
F
T
T
S
V
-----------
H
V
--
L
K
F
K
V
D
H
P
-------------
F
H
F
F
I
R
H
N
K
S
K
T
I
L
F
------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
43.84
26%
-40
- C4 -
1W7A
-
MUTS_ECOLI
A:
[342-438]
------------------------------------------------------------------------------------------
L
---
R
Q
V
G
D
-
L
-
E
R
I
L
A
R
L
A
L
R
T
--
A
R
-----
P
R
D
L
A
R
M
R
H
-------------
A
F
Q
Q
L
---
P
E
L
R
A
Q
L
E
T
---
V
---
D
S
A
P
V
Q
A
L
R
E
K
M
GEF
A
E
L
R
D
L
L
E
R
A
I
I
D
T
P
P
V
L
V
--------------------
R
D
G
G
V
I
A
--
S
G
Y
---
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
43.71
26%
-45
- C4 -
1OH8
-
MUTS_ECOLI
A:
[342-441]
------------------------------------------------------------------------------------------
L
---
R
Q
V
G
D
-
L
-
E
R
I
L
A
R
L
A
L
R
T
--
A
R
-----
P
R
D
L
A
R
M
R
H
-------------
A
F
Q
Q
L
---
P
E
L
R
A
Q
L
E
T
---
V
---
D
S
A
P
V
Q
A
L
R
E
K
M
GEF
A
E
L
R
D
L
L
E
R
A
I
I
D
T
P
P
V
L
V
--------------------
R
D
G
G
V
I
A
--
S
G
Y
---
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
43.56
26%
-51
- C4 -
1OH5
-
MUTS_ECOLI
A:
[342-441]
------------------------------------------------------------------------------------------
L
---
R
Q
V
G
D
-
L
-
E
R
I
L
A
R
L
A
L
R
T
--
A
R
-----
P
R
D
L
A
R
M
R
H
-------------
A
F
Q
Q
L
---
P
E
L
R
A
Q
L
E
T
---
V
---
D
S
A
P
V
Q
A
L
R
E
K
M
GEF
A
E
L
R
D
L
L
E
R
A
I
I
D
T
P
P
V
L
V
--------------------
R
D
G
G
V
I
A
--
S
G
Y
---
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
43.38
26%
-41
- C4 -
2WTU
-
MUTS_ECOLI
A:
[342-438]
------------------------------------------------------------------------------------------
L
---
R
Q
V
G
D
-
L
-
E
R
I
L
A
R
L
A
L
R
T
--
A
R
-----
P
R
D
L
A
R
M
R
H
-------------
A
F
Q
Q
L
---
P
E
L
R
A
Q
L
E
T
---
V
---
D
S
A
P
V
Q
A
L
R
E
K
M
GEF
A
E
L
R
D
L
L
E
R
A
I
I
D
T
P
P
V
L
V
--------------------
R
D
G
G
V
I
A
--
S
G
Y
---
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------