@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3413c: (2016-05-19 )
MREFGNPLGDRPPLDELARTDLLLDALAEREEVDFADPRDDALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRRRARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFNRSRVSDDQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVGNSWTPLAPVVEPPTPPTPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH
Atome Classification :
(20 SA)
----------------------------------------------------------.........10........20........30........40........50....---....60......----..70........80....----....90........100.-.....----------------..110........120...-.-----...130.----......140-.......150.......160--.........170--.---..----..----------...180.......190.......200.......210---..----...--------------------....220.......230....--.....240.--......250.......260.......270.......------280.......290.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------MREFGNPLGDRP
P
L
D
E
L
A
R
T
D
L
L
L
D
A
L
A
EREEVDFADPR
D
D
A
L
A
A
L
L
G
Q
W
R
D
DLR---WP
P
A
S
A
LVS
Q
D
E
----
A
V
A
A
L
R
A
G
V
A
Q
R
R
R
A
R
R
S
----
L
A
A
V
G
S
V
A
A
A
L
L
V
L
S-GF-
G
A
VVA----------------DARP-
G
D
L
L
Y
G
L
H
A
M
M
FNR-S-----RVSDD
Q
I
----
V
L
SAKA
N
L
A
-
K
V
E
Q
M
I
AQGQW
A
E
A
Q
D
E
L
----
A
E
V
S
S
T
V
Q
A
VT---D---
G
S
----
R
R
----------
Q
D
L
I
N
E
V
N
LLN
T
K
V
ETRDPNATLRPGSPSNPAAP-----GS----VGN--------------------SWTPLAPVVEPPTPP--TPAS--AAEPSMSAG--VSESPMPNSTSTVAASPSTPSSKPEPGSIDPSLEPA------DEATNPAGQPAPETPVSPTH
40
Fugue
72.36
17%
-4
- C3 -
4R1D
-
?
B:
[1-301]
---------------------------------------------------MDKTG
W
I
T
H
C
F
G
R
F
L
I
D
L
P
P
D
A
V
I
N
A
G
Y
Y
L
W
G
-----
D
R
I
E
Y
L
D
D
K
P
T
E
L
A
A
R
V
D
R
L
E
Q
E
W
R
T
QR
H
K
S
K
G
N
M
F
L
R
K
I
D
FGN
E
S
V
G
L
L
S
W
S
S
E
V
A
S
K
T
Y
L
----
L
D
T
Y
V
T
S
K
P
T
W
H
V
Y
R
-
W
K
-
G
K
V
S
V
----------------
D
R
E
Q
-
H
A
V
E
I
S
R
A
L
A
R
N
L
R
-
S
-----
R
A
P
K
E
I
P
S
E
P
G
F
C
I
D
H
A
Y
I
A
-
G
D
S
F
Q
V
E
R
F
G
V
G
V
T
F
P
E
H
----
P
G
A
R
F
E
F
R
S
S
T
---
G
---
A
E
----
L
N
----------
S
L
L
E
R
V
D
G
F
V
Q
N
M
L
S
T
F
A
G
M
E
T
L
R
K
G
K
H
P
V
G
S
L
P
-----
G
E
E
Y
L
V
A
G
S
--------------------
D
K
G
Q
R
G
Y
T
F
M
W
E
V
Q
G
--
K
E
E
S
--
L
T
E
P
N
L
T
A
G
--
L
A
V
L
E
R
S
N
-----------
E
N
G
K
P
P
P
----
P
A
F
K
S
D
------
K
E
A
L
E
L
W
D
T
I
V
D
S
I
R
V
R
P
T
S
35
Fugue
65.82
100%
-52
- C5 -
3VEP
1
RSDA_MYCTU
C:
[12-58]
---------------------------------------------------------------------
P
P
L
D
E
L
A
R
T
D
L
L
L
D
A
L
A
E
R
E
E
V
D
F
A
D
P
R
D
D
A
L
A
A
L
L
G
Q
W
R
D
D
L
R
---
W
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
65.82
100%
-52
- C5 -
3VEP
1
RSDA_MYCTU
C:
[12-58]
---------------------------------------------------------------------
P
P
L
D
E
L
A
R
T
D
L
L
L
D
A
L
A
E
R
E
E
V
D
F
A
D
P
R
D
D
A
L
A
A
L
L
G
Q
W
R
D
D
L
R
---
W
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
65.28
100%
-54
- C5 -
3VEP
1
RSDA_MYCTU
J:
[12-58]
---------------------------------------------------------------------
P
P
L
D
E
L
A
R
T
D
L
L
L
D
A
L
A
E
R
E
E
V
D
F
A
D
P
R
D
D
A
L
A
A
L
L
G
Q
W
R
D
D
L
R
---
W
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
62.01
14%
-27
- C6 -
4D10
-
CSN3_HUMAN
C:
[3-403]
S
A
L
E
Q
F
V
N
S
V
R
Q
L
SAQGQM
T
Q
L
C
E
L
I
N
K
SGELLAKN
L
S
H
L
D
T
V
LGALDVQE
H
S
L
G
V
L
A
V
L
F
V
K
F
S
M
P
S
V
P
D
F
E
T
L
F
S
Q
V
Q
L
F
I
S
T
C
N
G
E
H
I
R
Y
A
---
T
D
T
F
A
G
L
C
H
Q
L
T
N
A
L
V
---
E
R
K
Q
P
L
-----
R
----
G
I
G
I
L
K
Q
A
I
D
K
M
Q
M
N
T
N
Q
----
L
T
S
I
H
A
D
L
C
Q
L
C
L
L
A
K
C
F
-
K
P
A
L
P
Y
L
D
VDM
M
D
I
C
K
E
NGAY
D
A
K
H
-
F
L
C
Y
Y
Y
Y
G
G
M
I
Y
T
G
-
L
-----
K
--
N
F
E
R
----
A
L
Y
F
Y
E
Q
A
I
-
T
T
P
A
M
A
V
S
H
I
M
L
E
S
Y
K
K
Y
----
I
L
V
S
L
I
L
L
G
K
V
---
Q
---
Q
L
----
P
K
YTS
Q
I
V
G
R
F
I
K
P
L
S
N
A
Y
H
E
L
A
Q
V
Y
S
T
N
N
P
S
E
L
R
N
L
V
N
K
H
S
E
T
F
T
R
D
NN
M
G
L
----
V
K
Q
C
L
S
S
L
Y
K
K
N
I
Q
R
L
T
K
T
FLTL
S
L
Q
D
M
A
S
R
V
Q
L
S
G
P
Q
--
E
A
E
K
--
Y
V
L
H
M
I
E
D
G
EI
F
A
S
I
N
Q
K
D
G
M
V
S
F
H
D
N
P
E
K
Y
N
N
P
A
M
L
H
N
I
D
Q
E
M
L
K
C
------
I
E
L
D
E
R
L
K
A
M
D
Q
E
I
T
V
N
P
Q
F
7
PsiBlast_PDB
57.35
26%
-32
- C5 -
3QBM
4
?
A:
[3-121]
------------------------------------------------------------------------------------------------------------------------------------------------
R
K
G
Q
E
T
----
R
E
R
V
V
A
Q
A
A
A
L
F
N
V
S
-
G
Y
A
G
T
A
I
S
----------------
D
I
M
A
-
A
T
---
G
L
E
K
G
G
I
Y
R
-
H
-----
F
E
S
K
E
Q
L
----
A
L
A
A
F
D
Y
A
A
E
K
V
R
E
R
F
A
V
G
-
L
A
G
H
K
H
T
V
----
D
T
I
I
A
F
L
D
V
F
R
---
S
---
Y
A
----
E
R
----------
P
P
L
V
G
G
C
P
I
L
N
T
A
I
E
S
D
D
T
N
P
M
L
R
--------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
57.24
12%
-33
- C2 -
4HTP
1
DNLI4_HUMAN
A:
[7-237]
--------------------------------------------------------------
S
Q
T
V
A
S
H
V
P
F
A
D
L
C
S
---
T
L
E
R
I
Q
K
S
K
G
---
R
A
E
K
I
R
H
F
R
E
F
L
D
S
W
R
K
F
H
D
---
A
L
H
K
N
H
K
D
V
T
D
S
----
F
Y
P
A
M
R
L
I
L
P
Q
L
E
R
E
R
M
A
YGIK
E
T
M
L
A
K
L
Y
I
E
L
L
N
L
P
-
R
D
-
G
K
D
A
L
----------------
K
L
L
N
Y
G
D
F
A
M
I
A
Y
F
V
L
K
P
R
-
C
-----
L
-----------
Q
K
G
S
L
T
I
Q
-
Q
V
N
D
L
L
D
S
I
A
S
N
N
S
A
K
R
K
----
D
L
I
K
K
S
L
L
Q
L
I
---
T
---
Q
S
----
S
A
----------
L
E
Q
K
W
L
I
R
M
I
I
K
D
L
K
------------------------------
L
G
V
--------------------
S
Q
Q
T
I
F
S
V
F
H
N
D
A
A
E
--
L
H
N
V
--
T
-----------------
T
D
L
E
K
V
C
R
Q
L
H
D
P
S
V
G
L
S
D
------------------------------------
9
PsiBlast_PDB
51.62
30%
3
- C10 -
4A2D
1
?
A:
[283-350]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
--
P
V
E
P
T
T
S
Q
T
--
P
S
T
N
P
L
V
E
S
A
L
T
T
L
K
G
T
A
A
P
G
S
-
P
T
P
G
G
V
D
L
A
L
N
M
A
F
G
F
A
GG
N
F
T
I
N
G
A
S
F
T
P
P
T
V
P
V
----
13
PsiBlast_PDB
51.36
30%
3
- C10 -
4A2F
1
?
A:
[283-350]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
--
P
V
E
P
T
T
S
Q
T
--
P
S
T
N
P
L
V
E
S
A
L
T
T
L
K
G
T
A
A
P
G
S
-
P
T
P
G
G
V
D
L
A
L
N
M
A
F
G
F
A
GG
N
F
T
I
N
G
A
S
F
T
P
P
T
V
P
V
----
10
PsiBlast_PDB
51.00
30%
8
- C10 -
4A2E
1
?
A:
[283-350]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
--
P
V
E
P
T
T
S
Q
T
--
P
S
T
N
P
L
V
E
S
A
L
T
T
L
K
G
T
A
A
P
G
S
-
P
T
P
G
G
V
D
L
A
L
N
M
A
F
G
F
A
GG
N
F
T
I
N
G
A
S
F
T
P
P
T
V
P
V
----
11
PsiBlast_PDB
50.63
30%
23
- C10 -
4A2H
2
?
A:
[283-350]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
--
P
V
E
P
T
T
S
Q
T
--
P
S
T
N
P
L
V
E
S
A
L
T
T
L
K
G
T
A
A
P
G
S
-
P
T
P
G
G
V
D
L
A
L
N
M
A
F
G
F
A
GG
N
F
T
I
N
G
A
S
F
T
P
P
T
V
P
V
----
12
PsiBlast_PDB
50.46
30%
6
- C10 -
4A2G
1
?
A:
[283-350]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
--
P
V
E
P
T
T
S
Q
T
--
P
S
T
N
P
L
V
E
S
A
L
T
T
L
K
G
T
A
A
P
G
S
-
P
T
P
G
G
V
D
L
A
L
N
M
A
F
G
F
A
GG
N
F
T
I
N
G
A
S
F
T
P
P
T
V
P
V
----
36
Fugue
49.25
8%
-44
- C5 -
3AQB
-
HEXA_MICLU
A:
[4-138]
-----------------------------------------------------------------------------------------------------------------------------
M
M
R
----
Y
L
H
K
I
E
L
E
L
N
R
L
T
S
R
Y
P
F
----
F
K
K
I
A
F
D
A
E
I
I
K
L
V
D
-
D
L
-
N
-
V
D
E
----------------
N
V
K
C
-
A
I
V
A
I
D
T
S
M
R
M
Q
D
F
I
N
-----
E
D
N
K
D
S
F
----
V
L
S
T
D
V
L
S
A
-
L
F
Y
K
Y
L
S
Q
P
F
Y
Q
H
D
F
L
V
L
----
T
D
C
V
S
R
I
N
E
L
K
---
S
---
I
R
----
A
T
----------
I
T
D
E
I
A
L
H
N
I
N
K
Q
I
H
Y
M
F
I
Q
P
Y
M
---------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
49.10
18%
-1
- C4 -
4K6L
2
?
G:
[1-224]
-----------------------------------------------------------------------
V
D
F
V
Y
R
V
D
S
T
P
P
D
V
I
F
R
D
G
F
S
L
L
G
Y
N
R
N
F
Q
Q
F
I
S
G
R
-----------
S
C
S
G
G
S
S
D
S
R
----
Y
I
A
T
T
S
-----------
S
----
V
N
Q
T
Y
A
I
A
R
A
Y
Y
S
R
S
-
T
F
-
K
G
----------------------------------
N
L
Y
R
-
Y
-----
Q
I
R
A
D
N
N
----
F
Y
S
L
L
P
S
I
T
-
Y
L
E
T
Q
--
G
G
H
F
N
A
Y
E
K
T
M
----
M
R
L
Q
R
--
E
Y
V
S
---
T
---
L
S
----
I
L
----------
P
E
N
I
Q
K
A
V
A
L
V
Y
D
S
A
T
---
G
L
V
K
D
G
V
S
T
M
N
A
S
Y
L
-----
G
L
----
S
T
T
--------------------
S
N
P
G
V
I
P
F
L
P
E
P
Q
T
Y
--
T
Q
Q
R
ID
A
F
G
P
L
I
S
S
C
--
F
S
-------------
I
G
S
V
C
H
S
H
R
G
Q
R
A
D
V
Y
N
M
S
F
Y
------
D
------
A
R
P
V
I
E
L
I
L
S
K
--
38
Fugue
48.92
14%
-42
* C6 *
2E2E
2
NRFG_ECO57
A:
[2-177]
------------------------------------------------------------------------------------------------
K
W
Q
A
V
R
A
E
Y
Q
R
Q
R
D
P
L
H
---
Q
F
A
E
A
Q
L
Q
A
L
Q
D
----
K
I
R
A
N
P
Q
N
S
E
Q
W
A
L
L
G
E
Y
----
Y
L
W
Q
N
D
Y
S
N
S
L
L
A
Y
R
-
Q
A
-
L
Q
L
R
G
----------------
E
--
N
-
A
E
L
Y
A
A
L
A
T
V
L
Y
Y
Q
-
A
SQHMT
A
Q
T
R
A
M
I
----
D
K
A
L
A
L
D
S
N
-
E
I
T
A
L
M
L
L
A
S
D
A
F
M
Q
A
N
Y
----
A
Q
A
I
E
L
W
Q
K
V
M
---
D
---
L
N
SPRI
N
R
----------
T
Q
L
V
E
S
I
N
M
A
K
L
L
Q
R
R
S
D
L
E
H
H
H
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
48.03
20%
12
- C5 -
3ZSU
1
?
A:
[32-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
A
E
R
F
A
-
D
L
E
V
S
V
A
K
G
D
W
Q
E
A
R
N
I
M
R
G
P
L
G
E
M
L
M
D
M
R
A
L
N
---
R
N
LL
A
K
----
D
Q
----------
P
T
P
T
A
L
T
R
A
L
T
D
D
F
L
K
I
D
Q
G
A
D
L
D
--------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
47.85
32%
34
* C9 *
5EBC
1
?
A:
[52-139]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
R
L
V
L
G
N
P
A
N
P
A
T
V
-----
K
S
----
S
E
L
--------------------
S
K
L
P
M
G
Q
T
V
G
I
P
G
A
P
Y
A
T
P
V
S
--
A
G
S
T
S
I
W
T
L
--
C
D
T
V
A
R
A
D
S
T
S
P
V
V
Q
T
A
V
I
A
M
P
L
E
I
D
A
S
I
D
P
-------------------------------
16
PsiBlast_PDB
47.52
32%
29
- C9 -
5EBD
2
?
A:
[52-139]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
R
L
V
L
G
N
P
A
N
P
A
T
V
-----
K
S
----
S
E
L
--------------------
S
K
L
P
M
G
Q
T
V
G
I
P
G
A
P
Y
A
T
P
V
S
--
A
G
S
T
S
I
W
T
L
--
C
D
T
V
A
R
A
D
S
T
S
P
V
V
Q
T
A
V
I
A
M
P
L
E
I
D
A
S
I
D
P
-------------------------------
27
HHSearch
46.98
14%
-11
- C5 -
3LS0
-
?
A:
[50-122]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
R
D
G
M
E
K
R
L
Q
G
L
I
A
D
Q
N
W
V
D
T
Q
T
Y
I
H
G
P
L
G
Q
L
R
R
D
M
L
G
L
A
S
S
L
L
---
P
K
----
D
Q
----------
D
K
A
K
T
L
A
K
E
V
F
G
H
L
E
R
L
D
A
A
A
K
D
R
--------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.96
29%
-3
- C1 -
1YQ2
-
?
A:
[678-757]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
M
P
A
A
P
-----------
L
G
E
--------------------
T
W
L
T
V
E
A
V
L
R
D
A
T
G
W
--
A
P
A
G
--
H
P
L
G
A
V
Q
L
D
--
L
S
A
P
A
V
P
----
T
R
S
P
R
P
A
T
P
L
D
G
A
L
P
V
S
L
G
P
A
T
F
D
A
------
G
T
L
V
S
L
A
G
Q
P
----------