@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3427c: (2016-05-19 )
MSICDPALRNALRTLKLSGMLDTLDARLAQTRNGDLGHLEFLQALREDEIARRESAALTRRLRRAKFEAQATFEDFDFTANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQALVHAVARRGGDVRFAKTSRMLSDLAGGHADRSWGQRIREYTKPLVLILDDFAMREHTAMHADDLYELISDRAITGKPLILTSNRAPNNWYGLFPNPVVAESLLDRLINTSHQILMDGPSYRPRKRPGRTTS
Atome Classification :
(20 SA)
--------------------------------------------------------.........10........20........30........40........50........60........70---........80....-....90----......-..100.......110.......120-.....-.-------.------130------------.------------.------------...------------------------...140...----------------------.----------------------...150.....----..----160..-.....170..---......180..-.-.-...190.--.......200.......210-------.----.---.....220........230.......240.......250--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------MSIC
D
P
A
L
R
N
A
L
R
T
L
K
L
S
G
M
L
D
T
L
D
A
R
L
A
QTRNGDL
G
H
L
E
F
L
Q
A
L
R
E
D
E
I
A
R
R
E
S
A
A
L
T
R
R
L
R
R
A
KFEA
Q
A
---
T
FEDFDFTANPKL
P
-
G
A
M
L
R
D
----
L
A
A
L
R
W-LDAGE
S
V
I
L
HGPVGV
G
K
T
H
V
A
Q
A
L
V
-
H
A
V
A
R-R-------G------G-
D
------------
V
------------
R
------------
F
A
K
------------------------
T
S
R
M
L
S
D
L
A----------------------G----------------------GHA
D
R
S
W
G
Q
R
I
----
R
E
----YTK
P
L
-
V
L
I
L
D
D
F
-
A
M
---
R
E
HTAM
H
A
D
D
L
-
Y
-
E
-
L
I
SD-RA--ITGK
P
L
I
L
TSNRAPNNWYGL-------F----P---
N
P
V
V
A
E
S
-
L
L
D
R
L
INTS
H
Q
I
L
MDGPSYRPRKRPGRTTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
77.92
31%
-34
- C2 -
5BQ5
3
ISTB_GEOSE
A:
[8-187]
-----------------------------------------------------------------------------------------------------------------------------
R
K
---
T
I
D
T
F
D
F
T
A
Q
P
S
V
D
-
E
R
R
I
R
E
----
L
L
T
L
S
F
-
I
D
R
K
E
N
I
L
F
L
G
P
P
G
I
G
K
T
H
L
A
I
S
I
G
M
E
A
I
-
A
-
R
-------
G
------
Y
-
K
------------
T
------------
Y
------------
F
I
T
------------------------
A
H
D
L
V
N
Q
L
R
----------------------
R
----------------------
A
D
Q
E
G
K
L
E
K
K
L
----
R
V
----
F
V
K
P
T
-
V
L
I
I
D
E
-M
G
Y
---
L
K
L
D
P
N
S
A
H
Y
L
-
F
-
Q
-
V
I
A
R
-
R
---
Y
E
H
A
P
I
I
L
T
S
N
K
S
F
G
E
W
G
E
I
-------
V
----
G
---
D
S
V
L
A
T
A
M
L
-
D
R
L
L
H
H
S
I
I
F
N
L
K
G
E
S
Y
R
L
R
E
K
R
L
Q
E
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
76.29
30%
-44
- C2 -
5BQ5
3
ISTB_GEOSE
A:
[8-182]
-----------------------------------------------------------------------------------------------------------------------------
R
K
---
T
I
D
T
F
D
F
T
A
Q
P
S
V
D
-
E
R
R
I
R
E
----
L
L
T
L
S
F
-
I
D
R
K
E
N
I
L
F
L
G
P
P
G
I
G
K
T
H
L
A
I
S
I
G
-
M
E
A
I
A
-
R
-------
G
------
Y
-
K
------------
T
------------
Y
------------
F
I
T
------------------------
A
H
D
L
V
N
Q
L
R
----------------------
R
----------------------
A
D
Q
E
G
K
L
E
K
K
L
----
R
V
----
F
V
K
P
T
-
V
L
I
I
D
E
M
-
G
Y
---
L
K
L
D
P
N
S
A
H
Y
L
-
F
-
Q
-
V
I
A
--
R
R
--
Y
E
H
A
P
I
I
L
T
S
N
K
S
F
G
E
W
G
E
I
-------
V
----
G
---
D
S
V
L
A
T
A
-
M
L
D
R
L
L
H
H
S
I
I
F
N
L
K
G
E
S
Y
R
L
R
E
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
75.86
23%
-111
- C2 -
2W58
2
?
A:
[54-202]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
G
L
Y
L
H
G
S
F
G
V
G
K
T
Y
L
L
A
A
I
A
-
N
E
L
A
K
-
R
-------
N
------
V
-
S
------------
S
------------
L
------------
I
V
Y
------------------------
V
P
E
L
F
R
E
L
K
----------------------
H
----------------------
S
---
Q
T
M
N
E
K
L
----
D
Y
----
I
K
K
V
P
-
V
L
M
L
D
D
L
-
G
A
---
E
---
S
W
V
R
D
D
V
-
F
-
G
P
I
L
Q
Y
-
R
M
--
F
E
N
L
P
T
F
F
T
S
N
F
D
M
Q
Q
L
A
H
H
-------
L
----
T
YSQ-
K
V
K
A
A
R
-
I
M
E
R
I
R
Y
L
A
Y
P
I
E
I
T
G
P
N
R
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
74.59
17%
-80
- C2 -
2QGZ
2
?
A:
[100-300]
------------------------------------------------------------------------------------------------------------
Q
K
Q
A
A
I
S
E
R
I
Q
L
V
S
L
P
K
S
Y
RHI
H
L
S
D
I
D
V
N
N
A
S
R
M
E
A
F
S
A
I
L
D
----
F
V
E
Q
Y
P
-
S
A
E
Q
K
G
L
Y
L
Y
G
D
M
G
I
G
K
S
Y
L
L
A
A
M
A
-
H
E
L
S
E
-
K
-------
K
------
G
V
S
------------
T
------------
T
------------
L
L
H
------------------------
F
P
S
F
A
I
D
V
K
----------------------
N
----------------------
A
I
S
K
E
----
E
I
----
D
A
----
V
K
N
V
P
-
V
L
I
L
D
D
I
-
G
A
---
V
R
-----
D
E
V
L
-
Q
-
V
-
I
L
Q
Y
-
R
M
--
L
E
E
L
P
T
F
F
T
S
N
Y
S
F
A
D
L
E
R
K
-------
W
----
A
---
W
--
Q
A
K
R
-
V
M
E
R
V
R
Y
L
A
R
E
F
H
L
E
G
A
N
R
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.25
22%
-105
- C2 -
4M4W
-
DNAI_BACSU
J:
[129-309]
------------------------------------------------------------------------------------------------------------------------------
A
---
T
F
Q
Q
V
D
I
S
D
P
S
R
L
---
A
M
F
Q
H
VTDF
L
K
S
Y
N
E
-
T
G
K
G
K
G
L
Y
L
Y
G
K
F
G
V
G
K
T
F
M
L
A
A
I
A
-
N
E
L
A
E
-
K
-------
E
------
Y
-
S
------------
S
------------
M
------------
I
V
Y
------------------------
V
P
E
F
V
R
E
L
K
----------------------
N
----------------------
S
---
Q
T
L
E
E
K
L
----
N
M
----
V
K
T
T
P
-
V
L
M
L
D
D
I
-
G
A
---
E
S
---
W
V
R
D
E
V
-
I
G
T
-
V
L
Q
H
-
R
M
--
S
Q
Q
L
P
T
F
F
S
S
N
F
S
P
D
E
L
K
H
H
-------
F
TYSQ-----
E
V
K
A
A
R
-
L
M
E
R
I
L
Y
L
A
A
P
I
R
L
D
G
E
N
R
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
69.72
21%
-68
- C2 -
4F4C
-
PGP1_CAEEL
A:
[363-664]
----------------------------------------------------------------------
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
-
G
T
A
Q
G
A
A
S
G
I
Y
E
V
L
D
R
K
P
V
I
D
S
S
S
K
A
--
G
R
K
D
M
K
I
K
G
D
I
---
T
V
E
N
V
H
F
T
Y
P
S
R
P
D
-
V
P
I
L
R
G
-------
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
-
R
Y
Y
D
V
-
L
K
G
K
I
T
I
D
G
------
V
-
D
------------
V
RDIN
L
E
F
L
R
K
N
V
A
------------
V
V
S
Q
E
P
A
L
F
NCT
I
E
E
N
I
S
L
G
KEGIT--
R
E
E
M
V
A
A
C
K
M
A
NA
E
K
F
I
K
T
L
PNGYNTLVGDR
G
----------------------
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
----
V
R
N
P
K
-
I
L
L
L
D
E
A
--
T
---
S
A
L
D
A
E
S
E
G
I
V
-
Q
-
Q
-
A
L
D
K
-
A
A
--
K
G
R
T
-
T
I
I
I
A
H
R
L
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
68.20
19%
-67
- C2 -
4MRS
6
ATM1_NOVAD
A:
[309-556]
----------------------------------------------------------------------
T
Q
L
F
R
P
L
D
M
L
G
M
V
Y
R
T
I
-
R
Q
G
L
I
D
M
A
E
M
F
R
L
I
D
T
H
I
E
V
A
D
V
P
N
A
P
---
A
L
V
V
N
R
P
S
V
---
T
F
D
N
V
V
F
G
Y
D
R
D
---
R
E
I
L
H
G
----
L
S
-
F
E
--
V
A
A
G
S
R
V
A
I
V
G
P
S
G
A
G
K
S
T
I
A
R
L
L
F
-
R
F
Y
D
P
-
W
E
G
R
I
L
I
D
G
------
Q
-
D
------------
I
AHVT
Q
T
S
L
R
A
A
L
G
------------
I
V
P
Q
D
S
V
L
F
NDT
I
G
Y
N
I
A
YGRDGAS--
R
A
E
V
D
A
A
A
K
----------------------
G
A
AI
A
D
F
I
A
R
LPQGYDTEVGER
G
L
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
L
----
V
K
N
P
P
-
I
L
L
F
D
E
A
--
T
---
S
A
L
D
T
R
T
E
Q
D
I
-
L
-
S
-
T
M
R
A
-
V
A
--
S
H
R
T
-
T
I
S
I
A
H
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
67.90
25%
-101
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[40-169]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
-
N
E
A
K
K
-
R
-------
G
------
Y
-
R
------------
V
------------
I
------------
Y
S
S
------------------------
A
----
D
D
F
A
----------------------
Q
----------------------
A
M
V
E
H
L
K
K
G
T
I
----
N
E
F
R
N
M
Y
K
S
V
D
-
L
L
L
L
D
D
V
-
Q
F
LSG
K
E
R
T
Q
I
---
E
F
-
F
-
H
-
I
F
N
T
-
L
Y
--
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
----
E
---
G
G
I
L
V
E
I
-
E
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
67.71
24%
-97
- C2 -
3R8F
4
DNAA_AQUAE
A:
[40-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
-
N
E
A
K
K
-
R
-------
G
------
Y
-
R
------------
V
------------
I
------------
Y
S
S
------------------------
A
D
D
F
A
Q
A
M
V
---------------------------------------------
E
H
L
K
K
G
T
I
N
E
F
----
R
N
----
M
Y
K
S
V
D
L
L
L
L
D
D
V
-
Q
F
LSG
K
E
R
T
Q
I
---
E
F
-
F
-
H
-
I
F
N
T
-
L
Y
--
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
----
E
---
G
G
I
L
V
E
I
-
E
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
67.01
24%
-100
- C2 -
2HCB
3
DNAA_AQUAE
A:
[39-172]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
-
N
E
A
K
K
-
R
-------
G
------
Y
-
R
------------
V
------------
I
------------
Y
S
S
------------------------
A
D
D
F
A
Q
A
M
V
---------------------------------------------
E
H
L
K
K
G
T
I
N
E
F
----
R
N
----
M
Y
K
S
V
D
L
L
L
L
D
D
V
-
Q
F
LSG
K
E
R
T
Q
I
---
E
F
-
F
-
H
-
I
F
N
T
-
L
Y
--
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
----
E
---
G
G
I
L
V
E
I
-
E
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
66.16
24%
-85
- C2 -
3ECC
3
?
A:
[36-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
G
K
G
L
T
F
V
G
S
P
G
V
G
K
T
H
L
A
V
A
T
L
-
K
A
I
Y
E
-
K
-------
K
------
G
--------------
I
------------
R
G
Y
----------
F
F
D
------------------------
T
K
D
L
I
F
R
L
K
----------------------
H
----------------------
L
M
D
E
G
K
D
T
K
F
L
----
K
T
----
V
L
N
S
P
-
V
L
V
L
D
D
L
-
G
S
---
E
R
L
S
D
W
Q
R
E
L
I
-
S
-
Y
-
I
I
T
Y
-
R
Y
--
N
N
L
K
S
T
I
I
T
T
N
Y
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
65.55
19%
-68
* C2 *
3B60
2
MSBA_SALTY
A:
[292-539]
----------------------------------------------------------------------
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
-
Q
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
S
E
Q
E
K
D
E
G
K
R
-----
V
I
D
R
A
T
G
D
L
---
E
F
R
N
V
T
F
T
Y
P
G
R
E
--
V
P
A
L
R
N
----
I
N
-
L
K
--
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
-
R
F
Y
D
I
-
D
E
G
H
I
L
MD
G
------
H
-
D
------------
L
REYT
L
A
S
L
R
N
Q
V
A
------------
L
V
S
Q
N
V
H
L
F
NDT
V
A
N
N
I
A
YARTEEYS-
R
E
Q
I
E
E
A
A
R
----------------------
M
A
YA
M
D
F
I
N
K
M
DNGLD
T
I
I
G
ENG
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
----
L
R
D
S
P
-
I
L
I
L
D
E
A
--
T
---
S
A
L
D
T
E
S
E
R
A
I
-
Q
-
A
-
A
L
D
E
-
L
Q
--
K
N
R
T
-
S
L
V
I
A
H
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
65.05
16%
-76
- C2 -
4Q9H
-
MDR1A_MOUSE
A:
[982-1230]
--------------------------------------------------------------------------
M
A
V
G
Q
V
S
S
F
A
P
D
Y
-
A
K
A
T
V
S
A
S
H
I
I
R
I
I
E
K
T
P
E
I
D
S
Y
S
T
Q
G
--
L
K
P
N
M
L
E
G
N
V
---
Q
F
S
G
V
V
F
N
Y
P
T
R
P
S
-
I
P
V
L
Q
G
-------
L
S
L
E
V
K
K
G
Q
T
L
A
L
V
G
S
S
G
C
G
K
S
T
V
V
Q
L
L
E
-
R
F
Y
D
P
-
M
A
G
S
V
F
L
D
G
------
K
-
E
------------
I
------------
K
QLN
V
Q
W
L
R
A
Q
LG
I
V
S
Q
E
P
I
L
F
DCS
I
A
E
N
I
A
YGDNS
R
V
V
S
Y
E
E
I
V
R
A
A
K
E
A
NI
H
Q
F
I
D
S
LPDKYNTRVGDK
G
----------------------
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
----
V
R
Q
P
H
-
I
L
L
L
D
E
A
--
T
---
S
A
L
D
T
E
S
E
K
V
V
-
Q
-
E
-
A
L
D
K
-
A
R
--
E
G
R
T
-
C
I
V
I
A
H
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
65.01
20%
-89
- C2 -
2QGZ
1
?
A:
[152-300]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
G
L
Y
L
Y
G
D
M
G
I
G
K
S
Y
L
L
A
A
M
A
-
H
E
L
S
E
K
K
-------
G
------
V
-
S
------------
T
------------
T
------------
L
L
H
------------------------
F
P
S
F
A
I
D
V
K
----------------------
N
----------------------
A
I
S
----
K
E
E
I
----
D
A
----
V
K
N
V
P
-
V
L
I
L
D
D
I
-
G
A
---------
V
R
D
E
V
-
L
-
Q
-
V
I
L
Q
Y
R
M
--
L
E
E
L
P
T
F
F
T
S
N
Y
S
F
A
D
L
E
R
K
-------
W
A---------
W
Q
A
K
R
-
V
M
E
R
V
R
Y
L
A
R
E
F
H
L
E
G
A
N
R
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
64.79
24%
-85
- C2 -
3EC2
2
?
A:
[36-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
G
K
G
L
T
F
V
G
S
P
G
V
G
K
T
H
L
A
V
A
T
L
-
K
A
I
Y
E
-
K
-------
K
------
G
--------------
I
------------
R
G
Y
----------
F
F
D
------------------------
T
K
D
L
I
F
R
L
K
----------------------
H
----------------------
L
M
D
E
G
K
D
T
K
F
L
----
K
T
----
V
L
N
S
P
-
V
L
V
L
D
D
L
-
G
S
---
E
R
L
S
D
W
Q
R
E
L
I
-
S
-
Y
-
I
I
T
Y
-
R
Y
--
N
N
L
K
S
T
I
I
T
T
N
Y
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
64.77
17%
-66
- C2 -
4Q4H
-
Y288_THEMA
B:
[303-550]
---------------------------------------------------------------------
S
R
Q
F
T
R
P
L
N
E
L
S
N
Q
F
N
M
I
-
Q
M
A
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
----
V
E
L
R
E
V
R
G
E
I
---
E
F
K
N
V
W
F
S
Y
D
K
K
---
K
P
V
L
K
D
----
I
T
-
F
H
--
I
K
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
T
I
V
N
L
L
M
-
R
F
Y
D
V
-
D
R
G
Q
I
L
V
D
G
------
I
-
D
IRKIK
R
S
S
L
R
S
S
I
------------
G
------------
I
V
L
QD
T
I
L
F
STT
V
K
E
N
L
K
Y
GNPGAT--
D
E
E
I
K
E
A
A
K
----------------------
L
T
H
S
D
H
F
I
K
H
LPEGYETVLTDNG
E
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
----
L
A
N
P
K
-
I
L
I
L
D
E
A
--
T
---
S
N
V
D
T
K
T
E
K
S
I
-
Q
-
A
-
A
M
W
K
-
L
M
--
E
G
K
T
-
S
I
I
I
A
H
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
64.61
17%
-63
- C2 -
4MYC
-
ATM1_YEAST
A:
[383-633]
----------------------------------------------------------------------
F
Q
L
S
V
P
L
N
F
L
G
S
V
Y
R
D
L
-
K
Q
S
L
I
D
M
E
T
L
F
K
L
R
K
N
E
V
K
I
K
N
A
E
R
P
L
--
M
L
P
E
N
V
P
Y
D
I
---
T
F
E
N
V
T
F
G
Y
H
P
D
---
R
K
I
L
K
N
-------
A
S
F
T
I
P
A
G
W
K
T
A
I
V
G
S
S
G
S
G
K
S
T
I
L
K
L
V
F
-
R
F
Y
D
P
-
E
S
G
R
I
L
I
N
G
------
R
-
D
------------
I
KEYD
I
D
A
L
R
K
V
I
G
------------
V
V
P
Q
D
T
P
L
F
NDT
I
W
E
N
V
K
FGRIDAT--
D
E
E
V
I
T
V
V
E
----------------------
K
A
QL
A
P
L
I
K
K
LPQGFD
T
I
V
G
ER
G
L
M
I
S
G
G
E
K
Q
R
L
A
I
A
R
V
L
----
L
K
N
A
R
-
I
M
F
F
D
E
A
--
T
---
S
A
L
D
T
H
T
E
Q
A
L
-
L
-
R
-
T
I
R
D
-
N
F
TS
G
S
R
T
-
S
V
Y
I
A
H
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
64.58
15%
-70
- C2 -
4Q4H
-
?
A:
[280-528]
----------------------------------------------------------------------
M
Q
I
M
F
S
L
M
M
I
G
N
I
L
N
F
I
-
V
R
A
S
A
S
A
K
R
V
L
E
V
L
N
E
K
P
A
I
E
E
A
D
N
A
L
---
A
L
P
N
V
E
G
S
V
---
S
F
E
N
V
E
F
R
Y
F
E
N
T
--
D
P
V
L
S
G
----
V
N
-
F
S
--
V
K
P
G
S
L
V
A
V
L
G
E
T
G
S
G
K
S
T
L
M
N
L
I
P
-
R
L
I
D
P
-
E
R
------
G
R
V
E
V
DE
L
-
D
VRTVK
L
K
D
L
R
G
H
I
------------
S
------------
A
V
P
Q
E
T
V
L
F
S
GT
I
K
E
N
L
K
W
GREDAT--
D
D
E
I
V
E
A
A
K
----------------------
I
A
QI
H
D
F
I
I
S
LPEGYDSRVERGG
R
N
F
S
G
G
Q
K
Q
R
L
S
I
A
R
A
L
----
V
K
K
P
K
-
V
L
I
L
D
D
C
--
T
---
S
S
V
D
P
I
T
E
K
R
I
-
L
-
D
-
G
L
K
R
-
Y
T
--
K
G
C
T
-
T
F
I
I
T
Q
K
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
63.91
23%
-97
- C2 -
4M4W
-
DNAI_BACSU
J:
[159-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
G
K
G
L
Y
L
Y
G
K
F
G
V
G
K
T
F
M
L
A
A
I
A
-
N
E
L
A
E
-
K
-------
E
------
Y
-
S
------------
S
------------
M
------------
I
V
Y
------------------------
V
P
E
F
V
R
E
L
K
----------------------
N
----------------------
S
---
Q
T
L
E
E
K
L
----
N
M
----
V
K
T
T
P
-
V
L
M
L
D
D
I
-
G
A
---
E
S
---
W
V
R
D
E
V
I
G
-
T
-
V
L
Q
H
-
R
M
--
S
Q
Q
L
P
T
F
F
S
S
N
F
S
P
D
E
L
K
H
H
-------
F
----
T
YSQ-
E
V
K
A
A
R
-
L
M
E
R
I
L
Y
L
A
A
P
I
R
L
D
G
E
N
R
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
63.89
16%
-40
- C2 -
3E1S
-
RECDL_DEIRA
A:
[193-720]
FTLTEVEGIG
F
L
T
A
D
K
L
WDD
P
R
R
L
T
A
A
A
V
Y
A
L
Q
L
A
G
T
QAGHSFLP
R
S
R
A
E
K
G
V
V
H
Y
T
R
V
T
P
G
Q
A
R
L
A
V
E
T
A
V
E
L
G
R
L
S
E
D
D
S
P
L
F
A
A
A
T
G
E
-------
G
R
I
Y
L
P
H
V
L
R
A
E
K
K
L
A
S
L
I
R
T
L
L
A
T
P
P
A
D
---
A
G
N
D
D
W
A
V
P
K
K
A
R
K
-
G
L
S
E
E
Q
----
A
S
V
L
D
Q
-
L
A
G
H
R
L
V
V
L
T
G
G
P
G
T
G
K
S
T
T
T
K
A
V
A
-
D
L
A
E
S
-
L
-------
G
------
L
-
E
------------
V
------------
G
------------
L
C
A
------------------------
P
T
--------------------------------------------------------
G
K
A
A
R
R
L
----
G
E
----
V
T
G
R
T
-
A
S
T
V
H
R
L
-
L
G
---
Y
G
P
Q
G
F
R
H
N
H
L
-
E
-
P
-
A
P
Y
D
-
L
L
--
I
V
D
E
V
S
M
M
----------------------------
G
D
A
L
M
L
S
-
L
L
A
A
V
P
P
G
A
R
V
L
L
V
G
D
T
D
Q
L
P
P
V
D
A
G
L
P
L
L
A
L
A
Q
A
AP
T
I
K
L
TQVY
R
Q
A
A
K
N
P
I
I
Q
A
A
H
G
L
L
H
GEAPAWGDKR
L
N
L
T
E
I
E
PDGG
A
R
R
V
A
L
M
V
R
E
L
GGPGA
V
Q
V
L
T
PMRKGPLG
M
D
H
L
N
Y
H
L
Q
A
L
F
N
P
G
E
GGVRIA
E
G
E
A
R
PG
D
T
V
V
Q
TKNDYNNEIFNG
T
L
G
M
V
LKAEGA
R
L
T
V
D
F
DGNVVELTG
A
E
L
F
N
L
Q
L
G
YALTVHRAQGSEWG
T
V
L
G
V
L
H
EAHMPMLS
R
N
L
V
Y
T
A
L
T
R
ARD
R
F
F
S
A
G
S
A
S
A
W
Q
I
A
A
A
RQ
R
E
A
R
N
T
A
L
L
E
R
I
R
A
H
LEHHH