@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3513c: (2016-05-20 )
MAASLSENLSCHSSNMCRLSGNAATNLERPGEEPPGDRCTRRQAVRPARTLAKKGNIPVGYYKDEKKTAETFRTINGVRYAIPGDYAQVEEDGTVTMLGRGSVSINSGGEKVYPEEVEAALKGHPDVFDALVVGVPDPRYGQQVAAVVQARPGCRPSLAELDSFVRSEIAGYKVPRSLWFVDEVKRSPAGKPDYRWAKEQTEARPADDVHAGHVTSGS
Atome Classification :
(21 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10..-......20........30........40-------........50-....------.-----....-60........70.-.......80........90........100.......110.......120.......130.......140.......150..-----...---..160....-..-.170.-......180.......190.......200.......210......-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASLSENLSCHS-S
N
M
C
R
LSGNAATNLERPGEEPPG
D
R
C
T
R
-------
R
QAV
R
P
A
R
T
--
L
AKK------G-----NIPV-
G
Y
YKD
E
K
K
T
A
E
T
F
-
R
TIN
G
V
R
Y
AIPGDY
A
Q
VEEDG
T
V
T
M
L
GR
G
S
V
S
INSGGEKV
Y
P
E
E
V
E
A
A
LKGH
P
D
V
F
D
A
L
VVGVPDPR
Y
G
Q
Q
V
A
A
V
V
QARPGC-----R
P
S
---
L
A
E
L
D
S
F
V
R
-
S
E
-IAGYK-V
P
R
S
L
W
F
V
D
E
V
KRSPAGKPDYRW
A
K
E
QTEARPADDVHAGHVTSGS-
109
HHSearch
85.07
28%
-59
- C6 -
3C5E
2
ACS2A_HUMAN
A:
[374-562]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
M
G
T
A
A
S
C
Y
D
V
Q
I
I
D
DKG
N
-
V
L
P
P
G
T
E
G
D
--
I
G
I
R
VKP
I
R
P
I
-----
G
I
F
S
-
G
Y
V
D
N
P
D
K
T
A
A
N
I
-----
R
G
D
F
W
L
L
G
D
R
G
I
K
D
E
D
G
Y
F
Q
F
M
G
R
A
D
D
I
I
N
S
S
G
Y
R
I
G
P
S
E
V
E
N
A
L
M
E
H
P
A
V
V
E
T
A
V
I
S
S
P
D
P
V
R
G
E
V
V
K
A
F
V
V
L
A
S
Q
F
LSHD
P
E
Q
L
---
T
K
E
L
Q
Q
H
V
K
-
S
V
-
T
A
P
Y
K
-
Y
P
R
K
I
E
F
V
L
N
L
P
K
T
V
T
G
K
I
Q
R
A
K
L
R
D
K
E
W
K
----------------
124
HHSearch
84.88
34%
-73
* C6 *
1T5H
1
?
X:
[346-502]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
G
E
E
G
E
--
L
I
V
A
AS----
D
-----
S
A
F
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-----
Q
D
G
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
------------------
9
PsiBlast_PDB
82.70
34%
-78
- C6 -
1T5D
1
?
X:
[363-504]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
S
----------------
15
PsiBlast_PDB
82.61
34%
-80
- C6 -
3DLP
-
?
X:
[363-504]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
P
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
S
----------------
11
PsiBlast_PDB
82.35
34%
-76
- C6 -
1T5H
1
?
X:
[363-503]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
-----------------
12
PsiBlast_PDB
81.26
34%
-76
- C6 -
2QVZ
-
?
X:
[363-503]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
-----------------
10
PsiBlast_PDB
81.03
34%
-83
- C6 -
3CW9
3
?
A:
[363-503]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
-----------------
101
HHSearch
80.95
28%
-52
- C6 -
2D1S
3
LUCI_LUCCR
A:
[362-544]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
S
G
K
V
V
P
L
F
K
A
K
V
I
D
LDTK
K
S
L
G
P
N
R
R
G
E
--
V
C
V
K
G-----
P
-----
M
L
M
K
-
G
Y
V
N
N
P
E
A
T
K
E
L
I
----
D
E
E
G
W
L
H
T
G
D
I
G
Y
Y
D
E
E
K
H
F
F
I
V
D
R
L
K
S
L
I
K
Y
K
G
Y
Q
V
P
P
A
E
L
E
S
V
L
L
Q
H
P
S
I
F
D
A
G
V
A
G
V
P
D
P
V
A
G
E
L
P
G
A
V
V
V
L
E
S
G
K
-----
N
M
T
---
E
K
E
V
M
D
Y
V
A
-
S
Q
-
V
S
N
A
K
R
L
R
G
G
V
R
F
V
D
E
V
P
K
G
L
T
G
K
I
D
G
R
A
I
R
E
I
L
K
K
P
---------------
85
Fugue
80.81
24%
-47
- C6 -
1PG4
7
ACSA_SALTY
A:
[5-647]
HKHAIP
A
N
I
A
D
RCLIN
P
E
Q
Y
E
T
K
Y
K
Q
S
I
N
D
P
D
T
F
W
G
E
Q
G
KILDWITPYQK
V
K
N
T
S
FAPG
N
V
S
I
K
W
YED
G
T
L
N
L
A
A
N
C
LDRHLQENGDRTA
I
I
W
E
G
DDTS
Q
S
K
H
I
S
Y
R
E
L
H
R
D
V
C
R
F
A
N
T
L
L
D
L
GIKKG
D
V
V
A
I
YMPMV
P
E
A
A
V
A
M
L
A
C
A
R
I
GA
V
H
S
V
I
F
GGFS
P
E
A
V
A
G
C
I
I
D
S
SSR
L
V
I
T
A
D
E
G
V
R
AG
R
S
I
P
L
K
K
N
V
D
D
A
L
K
NPNVTSVE
H
V
I
V
L
KRTG
S
D
I
D
W
Q
E
GRDLW
W
R
D
L
I
E
K
ASP
E
H
Q
P
E
A
M
N
AEDPL
F
I
L
Y
T
S
G
STG
K
P
K
G
V
L
H
T
T
G
G
Y
L
V
Y
A
A
T
T
F
K
Y
V
F
DYHPG
D
I
Y
W
C
TADVGW
V
T
G
H
S
YLL
Y
G
P
L
A
C
G
A
T
T
L
M
F
EGVPNWPTPA
R
M
C
Q
V
V
D
K
H
QVN
I
L
Y
T
A
P
T
A
I
R
A
L
M
A
E
GDKAIEGTDRSSLR
I
L
G
S
V
G
E
P
I
N
P
E
A
W
E
W
Y
W
K
KIGKEK
C
P
V
V
D
T
W
W
Q
TETGGF
M
I
T
P
L
P
G
A
I
E
L
K
A
G
S
A
T
R
P
F
F
G
V
Q
P
A
L
V
D
N
E
G
H
P
Q
E
G
A
T
E
G
N
-------
L
V
I
T
D
S
W
P
G
--
Q
A
R
------------------
T
L
F
G
D
H
E
R
F
E
Q
T
Y
F
S
T
F
K
N
--
M
Y
F
S
G
D
G
A
R
R
D
E
D
G
Y
Y
W
I
T
G
R
V
D
D
V
L
N
V
S
G
H
R
L
G
T
A
E
I
E
S
A
L
V
A
H
P
K
I
A
E
A
A
V
V
G
I
P
H
A
I
K
G
Q
A
I
Y
A
Y
V
T
L
N
H
G
E
-----
E
P
S
P
E
L
Y
A
E
V
R
N
W
V
R
-
K
E
-
I
G
P
L
A
-
T
P
D
V
L
H
W
T
D
S
L
P
K
T
R
S
G
K
I
M
R
R
I
L
R
K
I
A
A
G
D
A
D
P
G
V
V
E
K
L
L
E
E
K
Q
A
118
HHSearch
80.68
28%
-74
- C6 -
3R44
1
FAC13_MYCTU
A:
[360-514]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
G
E
G
E
--
V
V
I
K
S
-----
D
-----
I
L
L
K
-
E
Y
W
N
R
P
E
A
T
R
D
A
F
-----
D
N
G
W
F
R
T
G
D
I
G
E
I
D
D
E
G
Y
L
Y
I
K
D
R
L
K
D
M
I
I
S
G
G
E
N
V
Y
P
A
E
I
E
S
V
I
I
G
V
P
G
V
S
E
V
A
V
I
G
L
P
D
E
K
W
G
E
I
A
A
A
I
V
V
A
D
Q
N
------
E
V
S
---
E
Q
Q
I
V
E
Y
C
G
-
T
R
-
L
A
R
Y
K
-
L
P
K
K
V
I
F
A
E
A
I
P
R
N
P
T
G
K
I
L
K
T
V
L
R
E
Q
Y
S
A
T
---------------
13
PsiBlast_PDB
80.55
34%
-73
- C6 -
2QW0
-
?
X:
[363-503]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
-----------------
7
PsiBlast_PDB
80.31
34%
-79
- C6 -
2QVX
-
?
X:
[363-502]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
------------------
8
PsiBlast_PDB
80.12
34%
-71
- C6 -
2QVY
-
?
X:
[363-503]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
-----------------
114
HHSearch
79.53
31%
-49
- C6 -
4RLQ
1
?
A:
[342-517]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
G
W
P
V
P
G
Y
Q
I
E
L
R
G
DGG
G
-
P
V
A
D
G
E
P
G
D
--
L
Y
I
H
G
-----
P
-----
S
S
A
T
-
M
Y
W
G
N
R
A
K
S
R
D
T
F
-----
Q
G
G
W
T
K
S
G
D
K
Y
V
R
N
D
D
G
S
Y
T
Y
A
G
R
T
D
D
M
L
K
V
S
G
I
Y
V
S
P
F
E
I
E
A
T
L
V
Q
H
P
G
V
L
E
A
A
V
V
G
V
A
D
E
H
G
L
T
K
P
K
A
Y
V
V
P
R
P
G
Q
-----
T
L
S
---
E
T
E
L
K
T
F
I
K
-
D
R
-
L
A
P
Y
K
-
Y
P
R
S
T
V
F
V
A
E
L
P
K
T
A
T
G
K
I
Q
R
F
K
L
R
E
G
V
------------------
22
PsiBlast_CBE
79.49
34%
-82
- C6 -
3CW9
4
?
B:
[363-503]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
Q
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
R
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
S
-----------------
6
PsiBlast_PDB
79.36
37%
-78
- C6 -
1MD9
2
DHBE_BACSU
A:
[373-519]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
P
G
E
T
G
H
L
L
T
R
------
G
-----
P
Y
T
I
R
G
Y
Y
K
A
E
E
H
N
A
A
S
F
--
T
E
D
G
--
F
Y
R
T
G
D
I
V
R
L
T
R
D
G
Y
I
V
V
E
G
R
A
K
D
Q
I
N
R
G
G
E
K
V
A
A
E
E
V
E
N
H
L
L
A
H
P
A
V
H
D
A
A
M
V
S
M
P
D
Q
F
L
G
E
R
S
C
V
F
I
I
P
R
D
E
A
------
P
K
---
A
A
E
L
K
A
F
L
R
-
E
R
G
L
A
A
Y
K
-
I
P
D
R
V
E
F
V
E
S
F
P
Q
T
G
V
G
K
----------------------------
111
HHSearch
79.32
29%
-64
- C6 -
4FUQ
2
?
A:
[321-500]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
G
P
A
L
P
G
V
S
A
R
V
T
DPETGK
E
L
P
R
G
D
I
G
M
--
I
E
V
K
G
-----
P
-----
N
V
F
K
-
G
Y
W
R
M
P
E
K
T
K
S
E
F
----
R
D
D
G
F
F
I
T
G
D
L
G
K
I
D
E
R
G
Y
V
H
I
L
G
R
G
K
D
L
V
I
T
G
G
F
N
V
Y
P
K
E
I
E
S
E
I
D
A
M
P
G
V
V
E
S
A
V
I
G
V
P
H
A
D
F
G
E
G
V
T
A
V
V
V
R
D
K
G
A
-----
T
I
D
---
E
A
Q
V
L
H
G
L
D
-
G
Q
-
L
A
K
F
K
-
M
P
K
K
V
I
F
V
D
D
L
P
R
N
T
M
G
K
V
Q
K
N
V
L
R
E
T
Y
K
D
----------------
14
PsiBlast_PDB
79.08
34%
-77
- C6 -
3CW8
1
?
X:
[363-502]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
G
Y
L
N
Q
P
E
A
T
A
E
K
L
-
Q
--
D
G
--
W
Y
R
T
S
D
V
A
V
W
T
P
E
G
T
V
R
I
L
G
R
V
D
D
M
I
I
S
G
G
E
N
I
H
P
S
E
I
E
R
V
L
G
T
A
P
G
V
T
E
V
V
V
I
G
L
A
D
Q
-
W
G
Q
S
V
T
A
C
V
V
P
R
L
G
E
-----
T
L
S
---
A
D
A
L
D
T
F
C
R
S
S
E
-
L
A
D
F
K
-
R
P
K
R
Y
F
I
L
D
Q
L
P
K
N
A
L
N
K
V
L
R
R
Q
L
V
Q
Q
V
------------------
117
HHSearch
78.89
32%
-62
- C6 -
1MDB
3
DHBE_BACSU
A:
[373-535]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
P
G
E
T
G
H
--
L
L
T
R
G-----
P
-----
Y
T
I
R
-
G
Y
Y
K
A
E
E
H
N
A
A
S
F
----
T
E
D
G
F
Y
R
T
G
D
I
V
R
L
T
R
D
G
Y
I
V
V
E
G
R
A
K
D
Q
I
N
R
G
G
E
K
V
A
A
E
E
V
E
N
H
L
L
A
H
P
A
V
H
D
A
A
M
V
S
M
P
D
Q
F
L
G
E
R
S
C
V
F
I
I
P
R
D
E
A
------
P
K
---
A
A
E
L
K
A
F
L
R
-
E
R
G
L
A
A
Y
K
-
I
P
D
R
V
E
F
V
E
S
F
P
Q
T
G
V
G
K
V
S
K
K
A
L
R
E
A
I
S
E
K
L
L
A
------------
4
PsiBlast_PDB
78.34
37%
-80
- C6 -
1MDB
3
DHBE_BACSU
A:
[373-519]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
P
G
E
T
G
H
L
L
T
R
------
G
-----
P
Y
T
I
R
G
Y
Y
K
A
E
E
H
N
A
A
S
F
--
T
E
D
G
--
F
Y
R
T
G
D
I
V
R
L
T
R
D
G
Y
I
V
V
E
G
R
A
K
D
Q
I
N
R
G
G
E
K
V
A
A
E
E
V
E
N
H
L
L
A
H
P
A
V
H
D
A
A
M
V
S
M
P
D
Q
F
L
G
E
R
S
C
V
F
I
I
P
R
D
E
A
------
P
K
---
A
A
E
L
K
A
F
L
R
-
E
R
G
L
A
A
Y
K
-
I
P
D
R
V
E
F
V
E
S
F
P
Q
T
G
V
G
K
----------------------------
95
HHSearch
73.90
32%
-64
- C6 -
3ETC
7
?
A:
[392-559]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
S
I
G
K
P
T
P
G
Y
K
I
E
L
M
D
RDG
R
-
L
C
E
V
G
E
E
G
E
--
I
V
I
N
T-----
M
EGKPV
G
L
F
V
-
H
Y
G
K
D
P
E
R
T
E
E
T
W
-----
H
D
G
Y
Y
H
T
G
D
M
A
W
M
D
E
D
G
Y
L
W
F
V
G
R
A
D
D
I
I
K
T
S
G
Y
K
V
G
P
F
E
V
E
S
A
L
I
Q
H
P
A
V
L
E
C
A
I
T
G
V
P
D
P
V
R
G
Q
V
I
K
A
T
I
V
L
T
K
D
Y
T
P
S
--
D
S
L
---
K
N
E
L
Q
D
H
V
K
-
N
V
-
T
A
P
Y
K
-
Y
P
R
I
I
E
F
V
P
E
------------------------------------