@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3833: (2016-05-23 )
MSENSHHRLATTSLTLPPGARIERHRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNPLMRELVIACSQADRTDTDEHHRMLAVLQDQLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAERHDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------.........10........20........30.......---------------.40.....--...50....--....60--........70----...------...--------..80........90---..-----......100.......110.---..-.....120.......130.......140.......150.......160.-.-......170.......180.......190....-...200...-.....-210.-.-.......---220.......230.......240.......250.......260.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------MSENS
H
H
R
L
A
T
T
S
LTLPPGARIERHRHPSH
Q
I
V
YPSA
G
---------------
A
V
S
V
T
THA--
G
T
W
I
TPVN
R
--
A
I
WIPA--GCWHQHKFHG----H
T
Q
------
F
H
G
--------
V
AL
D
P
Q
RYRGGPAT---
P
T
-----
V
L
A
V
N
P
L
M
R
E
L
V
I
A
CSQA-D---RT-D
T
D
E
H
H
R
M
L
A
V
L
Q
DQLPTTSIREPLWVPSP
T
D
R
R
L
R
H
A
C
A
L
I
A
DNLT-Q-
P
-
L
T
L
Q
Q
IGGRIGV
S
Q
R
T
L
S
R
L
F
S
D
ELGMT
F
P
Q
W
R
-
T
Q
L
R
L
-
Q
H
A
-
L
V
L
L
A-E--R-H-
D
V
T
S
V
A
S
---ECGWAT
P
S
A
F
I
D
T
Y
R
Q
A
FGHTPGQAAK
P
M
A
A
T
R
L
T
R
L
R
R
ARDRR
1
PsiBlast_PDB
78.87
33%
-125
- C2 -
3OIO
2
?
A:
[8-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
T
E
A
V
S
L
M
E
A
N
I
E
-
E
-
P
-
L
S
T
D
D
I
A
Y
Y
V
G
V
S
R
R
Q
L
E
R
L
F
K
Q
Y
L
G
T
V
P
S
K
Y
Y
-
L
E
L
R
L
-
N
R
A
-
R
Q
L
L
Q
-
Q
T-
S
-
K
-
S
I
V
Q
I
G
L
---
A
C
G
F
S
S
G
P
H
F
S
S
T
Y
R
N
H
F
N
I
T
P
----------------------
26
HHSearch
75.62
31%
-110
- C2 -
3OIO
2
?
A:
[5-110]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
P
K
L
T
E
A
V
S
L
M
E
A
N
I
E
-
E
-
P
-
L
S
T
D
D
I
A
Y
Y
V
G
V
S
R
R
Q
L
E
R
L
F
K
Q
Y
L
G
T
V
P
S
K
Y
Y
-
L
E
L
R
L
-
N
R
A
-
R
Q
L
L
Q
-
Q
--
T
S
K
-
S
I
V
Q
I
G
L
---
A
C
G
F
S
S
G
P
H
F
S
S
T
Y
R
N
H
F
N
I
T
P
R
E
E
R
A
Q
R
A
--------------
50
Fugue
72.63
16%
-80
- C2 -
4FE7
1
XYLR_ECOLI
A:
[21-409]
MFT
K
R
H
R
I
T
L
L
F
N
ANK
A
Y
D
R
Q
V
V
E
G
V
G
E
Y
L
Q
A
S
QSEWDIFIEEFRWLGD
G
V
I
A
DFDD
K
Q
I
E
Q
A
L
ADVD
V
P
I
V
G
V
G
G
S
Y
HLAESYPP
V
H
Y
I
A
T
D
N
Y
A
L
V
E
S
A
F
L
H
L
K
E
K
G
V
N
R
F
A
F
Y
G
L
P
E
S
S
G
K
R
W
A
T
E
R
E
Y
A
F
R
Q
L
V
A
E
E
K
Y
R
G
V
V
Y
Q
G
LETAPEN
W
Q
H
A
Q
N
R
L
--
A
D
W
L
Q
T
L
P
P
Q
T
G
I
I
A
V
T
--
D
A
R
A
R
H
I
L
Q
V
----
C
E
H
------
L
H
I
PVPEK
L
C
V
I
G
I
D
N
E
E
L
T
R
Y
L
S
R
---
V
A
-----
L
S
S
V
A
Q
G
A
R
Q
M
G
Y
Q
A
A
K
L
-
L
---
H
R
-
L
L
D
K
E
E
M
P
L
Q
R
I
L
V
P
P
V
R
V
I
E
R
R
S
T
D
Y
R
S
L
T
D
P
A
V
I
Q
A
M
H
Y
I
R
N
H
A
C
-
K
-
G
-
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
-
H
A
E
K
L
-
E
K
A
-
R
S
L
L
I
-
S
--
T
-
T
L
S
I
N
E
I
S
Q
---
M
C
G
Y
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
T
T
P
K
E
Y
R
D
V
N
S
E
-------------
28
HHSearch
70.97
25%
-112
- C2 -
2K9S
-
A:
[3-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
V
R
E
A
C
Q
Y
I
S
D
H
L
A
-
D
S
N
-
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
S
W
R
-
E
D
Q
R
I
-
S
Q
A
-
K
L
L
L
S
-
T
--
T
R
M
-
P
I
A
T
V
G
R
---
N
V
G
F
D
D
Q
L
Y
F
S
R
V
F
K
K
C
T
G
A
S
P
S
E
F
R
A
G
----------------
2
PsiBlast_PDB
70.80
27%
-105
- C2 -
2K9S
-
A:
[2-101]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
R
V
R
E
A
C
Q
Y
I
S
D
H
L
A
-
D
-
S
N
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
S
W
R
-
E
D
Q
R
I
-
S
Q
A
-
K
L
L
L
S
T
T
--
R
-
M
-
P
I
A
T
V
G
R
---
N
V
G
F
D
D
Q
L
Y
F
S
R
V
F
K
K
C
T
G
A
S
P
S
E
--------------------
29
HHSearch
70.67
27%
-109
- C2 -
3MN2
2
?
A:
[3-107]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
R
Q
V
E
E
Y
I
E
A
N
W
M
-
R
-
P
-
I
T
I
E
K
L
T
A
L
T
G
I
S
S
R
G
I
F
K
A
F
Q
R
S
R
G
Y
S
P
M
A
F
A
-
K
R
V
R
L
-
Q
H
A
-
H
N
L
L
S
-
D
GA
T
P
T
-
T
V
T
A
A
A
L
---
S
C
G
F
S
N
L
G
H
F
A
R
D
Y
R
D
M
F
G
E
K
P
S
E
T
L
Q
R
A
R
--------------
23
HHSearch
69.88
21%
-107
- C2 -
4FE7
-
XYLR_ECOLI
A:
[303-409]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
P
A
V
I
Q
A
M
H
Y
I
R
N
H
A
C
-
K
-
G
-
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
-
H
A
E
K
L
-
E
K
A
-
R
S
L
L
I
-
S
--
T
T
L
-
S
I
N
E
I
S
Q
---
M
C
G
Y
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
T
T
P
K
E
Y
R
D
V
N
S
E
-------------
3
PsiBlast_PDB
68.63
27%
-114
- C2 -
3MN2
2
?
A:
[4-101]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
Q
V
E
E
Y
I
E
A
N
W
M
-
R
-
P
-
I
T
I
E
K
L
T
A
L
T
G
I
S
S
R
G
I
F
K
A
F
Q
R
S
R
G
Y
S
P
M
A
F
A
-
K
R
V
R
L
-
Q
H
A
-
H
N
L
L
S
-
D
--
G
-
A
-
T
P
T
T
V
T
A
A
A
L
S
C
G
F
S
N
L
G
H
F
A
R
D
Y
R
D
M
F
G
E
K
P
S
E
--------------------
8
PsiBlast_PDB
68.17
21%
-108
- C2 -
4FE7
-
XYLR_ECOLI
A:
[301-402]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
D
P
A
V
I
Q
A
M
H
Y
I
R
N
H
A
C
-
K
-
G
-
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
-
H
A
E
K
L
-
E
K
A
R
S
L
L
I
S
-
T
--
T
-
L
-
S
I
N
E
I
S
Q
---
M
C
G
Y
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
T
T
P
K
E
--------------------
9
PsiBlast_PDB
67.58
28%
-110
- C2 -
3W6V
2
?
A:
[40-133]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
E
V
V
A
W
A
L
E
H
L
H
-
E
-
Q
-
F
D
V
E
T
L
A
A
R
A
Y
M
S
R
R
T
F
D
R
R
F
R
S
L
T
G
S
A
P
L
Q
W
L
I
T
Q
R
V
L
-
Q
A
Q
-
R
L
L
E
T
-
S
--
D
-
Y
-
S
V
D
E
V
A
G
---
R
C
G
F
R
S
P
V
A
L
R
G
H
F
R
R
Q
L
G
S
S
P
----------------------
27
HHSearch
66.93
26%
-102
- C2 -
3W6V
2
?
A:
[37-144]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
P
L
A
E
V
V
A
W
A
L
E
H
L
H
-
E
-
Q
-
F
D
V
E
T
L
A
A
R
A
Y
M
S
R
R
T
F
D
R
R
F
R
S
L
T
G
S
A
P
L
Q
W
L
-
I
T
Q
R
V
-
L
Q
A
-
Q
R
L
L
E
-
T
--
S
D
Y
-
S
V
D
E
V
A
G
---
R
C
G
F
R
S
P
V
A
L
R
G
H
F
R
R
Q
L
G
S
S
P
A
A
Y
R
A
A
Y
R
A
R
R
-----------
22
HHSearch
66.76
8%
-97
- C2 -
3GBG
1
TCPN_VIBC3
A:
[17-273]
------------------------------------------------------------------------------------------------------------------------
F
D
T
Y
I
F
N
N
L
Y
I
N
D
Y
K
M
F
W
I
D
S
G
---------------
I
A
K
L
I
D
K
N
CL
V
S
Y
E
I
N
S
S
S
--
I
I
L
L
K
K
--
N
S
I
Q
R
F
S
L
T
S
LSD
E
N
I
N
------
V
S
V
--------
I
T
I
S
D
S
F
I
R
S
L
K
S
Y
ILG--NKD
L
L
L
W
N
C
E
H
N
D
I
A
V
L
S
E
V
V
N
G
F
R
E--
I
N
Y
S
D
E
F
L
K
V
F
F
S
G
F
F
S
K
V
E
K
K
Y
-
N
--
S
I
F
I
T
D
D
L
D
A
M
E
K
I
S
C
L
V
K
S
D
I
T
-
R
-
N
-
W
R
W
A
D
I
C
G
E
L
R
T
N
R
M
I
L
K
K
E
L
E
-
S
R
G
V
K
F
R
E
L
I
-
N
S
I
R
I
-
S
Y
S
-
I
S
L
M
K
-
T
--
G
E
F
-
K
I
K
Q
I
A
Y
---
Q
S
G
F
A
S
V
S
Y
F
S
T
V
F
K
S
T
M
N
V
A
P
S
E
Y
L
F
M
L
T
G
V
------------
31
HHSearch
66.42
22%
-109
- C2 -
3LSG
1
?
A:
[3-103]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
E
L
I
Q
N
I
I
E
E
S
Y
T
D
S
-
Q
-
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
D
Y
L
-
L
Q
K
R
M
-
E
K
A
-
K
L
L
L
L
-
T
--
T
E
L
-
K
N
Y
E
I
A
E
---
Q
V
G
F
E
D
V
N
Y
F
I
T
K
F
K
K
Y
Y
Q
I
T
P
K
Q
Y
R
E
-----------------
7
PsiBlast_PDB
63.56
21%
-102
- C2 -
4FE4
-
XYLR_ECOLI
A:
[281-382]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
D
P
A
V
I
Q
A
M
H
Y
I
R
N
H
A
C
-
K
-
G
-
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
-
H
A
E
K
L
-
E
K
A
R
S
L
L
I
S
-
T
--
T
-
L
-
S
I
N
E
I
S
Q
---
M
C
G
Y
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
T
T
P
K
E
--------------------
43
Fugue
63.04
8%
-83
- C2 -
3GBG
1
TCPN_VIBC3
A:
[4-273]
-----------------------------------------------------------------------------------------------------------
K
K
S
F
Q
T
N
V
Y
R
M
S
K
F
D
T
Y
I
F
N
N
L
Y
I
N
D
Y
K
M
F
W
I
D
S
G
---------------
I
A
K
L
I
D
K
N
C-
L
V
S
Y
E
I
N
S
S
--
S
I
I
L
L
K
K
N
S
I
Q
R
F
S
L
T
S
L
----
S
D
E
N
I
N
V
S
V
I
T
I
--------
S
D
S
F
I
R
S
L
K
S
Y
I
L
G
---
N
K
-----
D
L
L
L
W
N
C
E
H
N
D
I
A
V
L
S
E
V
-
V
N
GF
R
E
-
I
N
Y
S
D
E
F
L
K
V
F
F
S
G
F
F
S
K
V
E
K
K
Y
N
S
I
F
I
T
D
D
L
D
A
M
E
K
I
S
C
L
V
K
S
D
I
T
-
R
-
N
-
W
R
W
A
D
I
C
G
E
L
R
T
N
R
M
I
L
K
K
E
L
E
-
S
R
G
V
K
F
R
E
L
I
-
N
S
I
R
I
-
S
Y
S
-
I
S
L
M
K
-
T
G-
E
-
F
-
K
I
K
Q
I
A
Y
---
Q
S
G
F
A
S
V
S
Y
F
S
T
V
F
K
S
T
M
N
V
A
P
S
E
Y
L
F
M
L
T
G
V
------------
24
HHSearch
62.66
19%
-107
- C2 -
3OOU
1
?
A:
[4-107]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
I
Q
N
V
L
S
Y
I
T
E
H
F
S
-
E
-
G
-
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
-
N
R
Y
R
V
-
N
Y
A
-
K
E
E
L
L
-
Q
--
T
K
D
-
N
L
T
I
I
A
G
---
K
S
G
Y
T
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
E
T
P
N
R
Y
R
K
I
H
---------------
32
HHSearch
61.23
21%
-96
- C2 -
1D5Y
2
ROB_ECOLI
A:
[3-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
I
R
D
L
L
I
W
L
E
G
H
L
D
-
Q
-
P
-
L
S
L
D
N
V
A
A
K
A
G
Y
S
K
W
H
L
Q
R
M
F
K
D
V
T
G
H
A
I
G
A
Y
I
-
R
A
R
R
L
-
S
K
S
-
A
V
A
L
R
-
L
--
T
A
R
-
P
I
L
D
I
A
L
---
Q
Y
R
F
D
S
Q
Q
T
F
T
R
A
F
K
K
Q
F
A
Q
T
P
A
L
Y
R
R
S
P
E
W
-------------
10
PsiBlast_PDB
60.64
23%
-94
- C2 -
1D5Y
2
ROB_ECOLI
A:
[5-102]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
D
L
L
I
W
L
E
G
H
L
D
-
Q
-
P
-
L
S
L
D
N
V
A
A
K
A
G
Y
S
K
W
H
L
Q
R
M
F
K
D
V
T
G
H
A
I
G
A
Y
I
-
R
A
R
R
L
S
K
S
A
-
V
A
L
R
L
-
T
--
A
-
R
-
P
I
L
D
I
A
L
---
Q
Y
R
F
D
S
Q
Q
T
F
T
R
A
F
K
K
Q
F
A
Q
T
P
----------------------
42
Fugue
60.50
20%
-80
* C2 *
1BL0
2
MARA_ECOLI
A:
[9-124]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
T
I
H
S
I
L
D
W
I
E
D
N
L
E
-
S
-
P
-
L
S
L
E
K
V
S
E
R
S
G
Y
S
K
W
H
L
Q
R
M
F
K
K
E
T
G
H
S
L
G
Q
Y
I
-
R
S
R
K
M
-
T
E
I
-
A
Q
K
L
K
-
E
S-
N
-
E
-
P
I
L
Y
L
A
E
---
R
Y
G
F
E
S
Q
Q
T
L
T
R
T
F
K
N
Y
F
D
V
P
P
H
K
Y
R
M
T
N
M
Q
G
E
S
R
F
L
H
P
L
----
25
HHSearch
59.03
21%
-80
- C2 -
1BL0
2
MARA_ECOLI
A:
[9-118]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
T
I
H
S
I
L
D
W
I
E
D
N
L
E
-
S
-
P
-
L
S
L
E
K
V
S
E
R
S
G
Y
S
K
W
H
L
Q
R
M
F
K
K
E
T
G
H
S
L
G
Q
Y
I
-
R
S
R
K
M
-
T
E
I
-
A
Q
K
L
K
-
E
--
S
N
E
-
P
I
L
Y
L
A
E
---
R
Y
G
F
E
S
Q
Q
T
L
T
R
T
F
K
N
Y
F
D
V
P
P
H
K
Y
R
M
T
N
M
Q
G
E
S
----------