@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3855: (2016-05-23 )
MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Atome Classification :
(35 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTTSAASQASLPRGRRTARPSGDDR
E
L
A
I
L
A
T
A
E
N
L
LEDRPLADI
S
V
D
D
L
AKGAGISR
P
T
F
Y
F
YFPSK
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
AENPADT
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
FGS
H
K
A
V
T
RAGQAARAT
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
DAERDRGAAPRTL
P
A
H
E
L
A
T
A
L
N
L
MNER
T
L
F
A
S
FAGEQPSV
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
YGENR
26
PsiBlast_CBE
94.40
99%
-126
- C2 -
5F0F
2
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
98
HHSearch
94.12
100%
-127
- C2 -
3G1L
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
1
PsiBlast_PDB
93.94
100%
-127
* C2 *
3G1L
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
7
PsiBlast_PDB
93.83
100%
-127
- C2 -
3SFI
1
ETHR_MYCTU
A:
[42-234]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
99
HHSearch
93.62
100%
-125
- C2 -
5EYR
1
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
89
Fugue
93.47
100%
-125
- C2 -
1T56
3
ETHR_MYCTU
A:
[22-214]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
13
PsiBlast_PDB
93.30
100%
-125
- C2 -
1T56
3
ETHR_MYCTU
A:
[22-214]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
4
PsiBlast_PDB
93.30
100%
-130
- C2 -
3O8G
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
28
PsiBlast_CBE
93.24
99%
-121
- C2 -
5F08
1
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
32
PsiBlast_CBE
93.23
99%
-125
- C2 -
5EYR
1
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
31
PsiBlast_CBE
93.15
99%
-125
- C2 -
5EZG
3
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
30
PsiBlast_CBE
93.00
99%
-123
- C2 -
5EZH
3
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
2
PsiBlast_PDB
93.00
100%
-125
- C2 -
3G1O
1
ETHR_MYCTU
A:
[41-234]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
18
PsiBlast_PDB
92.84
100%
-125
- C2 -
4M3F
1
ETHR_MYCTO
A:
[22-214]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
27
PsiBlast_CBE
92.53
99%
-126
- C2 -
5F0C
3
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
25
PsiBlast_CBE
92.49
99%
-124
- C2 -
5F0H
1
?
A:
[26-218]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
19
PsiBlast_PDB
92.35
100%
-124
- C2 -
4M3G
1
ETHR_MYCTU
A:
[22-214]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
--
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
21
PsiBlast_CBE
92.27
100%
-129
- C2 -
3Q0V
1
ETHR_MYCTU
B:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
9
PsiBlast_PDB
92.27
100%
-126
- C2 -
3Q0U
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
8
PsiBlast_PDB
92.24
100%
-121
- C2 -
3Q0W
2
ETHR_MYCTU
A:
[42-234]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
24
PsiBlast_CBE
92.18
99%
-125
- C2 -
5F1J
2
?
A:
[26-219]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
17
PsiBlast_PDB
91.82
100%
-124
- C2 -
4M3E
1
ETHR_MYCTU
A:
[22-214]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
29
PsiBlast_CBE
91.81
99%
-127
- C2 -
5F04
5
?
A:
[28-218]
-----------------------
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
5
PsiBlast_PDB
91.55
100%
-127
- C2 -
3O8H
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
3
PsiBlast_PDB
91.28
100%
-125
- C2 -
3G1M
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
11
PsiBlast_PDB
91.22
100%
-122
- C2 -
3Q3S
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
14
PsiBlast_PDB
91.17
100%
-130
- C2 -
3TP0
1
ETHR_MYCTU
A:
[24-214]
-----------------------
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
---
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
10
PsiBlast_PDB
90.59
100%
-130
- C2 -
3Q0V
1
ETHR_MYCTU
A:
[42-234]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
-----
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
16
PsiBlast_PDB
90.43
100%
-122
- C2 -
4M3D
1
ETHR_MYCTU
A:
[23-214]
----------------------
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
15
PsiBlast_PDB
89.98
100%
-129
- C2 -
4M3B
1
ETHR_MYCTU
A:
[25-214]
------------------------
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
-----
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
23
PsiBlast_CBE
89.83
99%
-131
- C2 -
5F27
2
?
A:
[28-218]
-----------------------
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
----
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
12
PsiBlast_PDB
89.44
100%
-126
- C2 -
4DW6
5
ETHR_MYCTU
A:
[44-234]
-----------------------
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
---
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
20
PsiBlast_PDB
89.22
99%
-126
- C2 -
1U9O
1
ETHR_MYCTU
A:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-
6
PsiBlast_PDB
89.09
100%
-130
- C2 -
3SDG
1
ETHR_MYCTU
A:
[46-234]
-------------------------
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
-----
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
--
22
PsiBlast_CBE
88.79
99%
-120
- C2 -
1U9O
1
ETHR_MYCTU
B:
[42-235]
---------------------
G
D
D
R
E
L
A
I
L
A
T
A
E
N
L
L
E
D
R
P
L
A
D
I
S
V
D
D
L
A
K
G
A
G
I
S
R
P
T
F
Y
F
Y
F
P
S
K
E
A
V
L
L
T
L
L
D
R
V
V
N
Q
A
D
M
A
L
Q
T
L
A
E
N
P
A
D
T
D
R
E
N
M
W
R
T
G
I
N
V
F
F
E
T
F
G
S
H
K
A
V
T
R
A
G
Q
A
A
R
A
T
S
V
E
V
A
E
L
W
S
T
F
M
Q
K
W
I
A
Y
T
A
A
V
I
D
A
E
R
D
R
G
A
A
P
R
T
L
P
A
H
E
L
A
T
A
L
N
L
M
N
E
R
T
L
F
A
S
F
A
G
E
Q
P
S
V
P
E
A
R
V
L
D
T
L
V
H
I
W
V
T
S
I
Y
G
E
N
-