@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3881c: (2016-05-24 )
MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENPSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
Atome Classification :
(20 SA)
.........10...------.....20........30.---..-..--...40.--.......-----------50........60.------.......70........80........90.-----......----------.---100.....------..110..-----.....120.......130.......140..-.-...-.150.......160-.....-------..-..170----.-.-----......180.......190.------------------...-...200.......210.......220.......230..--.....---------240-------.....------------....250.-----......260.....--..270--------.........280.......290----........300.......310........320.......330.......340..--------.....350.......360.......370.......380.......390.......400.......410.......----------420.......430.......440.......450.......460
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTQS
Q
T
V
T
V
D
Q
Q
E
I
------
L
N
R
A
N
EVEAPMADPPTDV---PI-T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
YGE
V
D
E
E
A
A
TAL-----DNDGE
G
----------
T
---
V
Q
AESAGA------VGGDSSA-----ELTDTPRVATAGEP
N
F
M
D
L
K
E
A
A
R
KLETGD-Q-GAS-L
A
H
FADG
W
N
T
F
N
---
L
T
LQG-------D
V
-
K
R
FR-----G-F-----DNWEGD
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
ARREHP
T
Y
E
D
I
V
G
L
E
R
--
L
YAEN---------P---------SARDQ------------I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
YNNK--AAL----------EPVNPPKPPP
A
I
KIDPPPPPQ-----EQGLIPGFLMPPSDGSGVT-PGTGMPAAPMVPPTGSPGGGLP
A
D
T
A
A
Q
L
T
SAGR--------EAAALSG
D
V
A
V
K
A
A
SLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQ----------GQGGAKSKGSQQE
D
E
A
LYTED
R
A
W
T
E
A
V
IGNRRRQDSKESK--
2
PsiBlast_PDB
94.32
100%
-62
- C3 -
3J83
-
ESPB_MYCTU
A:
[11-286]
----------
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
G
E
V
D
E
E
A
A
T
A
L
-----
D
N
D
G
E
G
----------
T
---
V
Q
A
E
S
A
G
A
------
V
G
G
D
S
S
A
-----
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
P
P
A
I
K
I
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
92.03
99%
-76
- C3 -
4XXX
3
ESPB_MYCTU
A:
[2-275]
----
A
M
V
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
G
E
V
D
E
E
A
A
------------------------------------------------------
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
91.50
100%
-76
- C3 -
4XXX
3
ESPB_MYCTU
A:
[4-275]
------
V
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
G
E
V
D
E
E
A
A
------------------------------------------------------
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
91.49
99%
-76
- C3 -
4XXX
3
ESPB_MYCTU
A:
[2-275]
----
A
M
V
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
G
E
V
D
E
E
A
A
------------------------------------------------------
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
90.85
100%
-70
- C3 -
4XY3
-
ESPB_MYCTU
A:
[8-283]
-------
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
--------------------------------------------------------------
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
P
P
A
I
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
90.49
98%
-70
- C3 -
4XY3
-
ESPB_MYCTU
A:
[8-283]
-------
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
--------------------------------------------------------------
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
P
P
A
I
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
90.06
100%
-74
- C3 -
4XXN
2
ESPB_MYCTU
A:
[4-275]
------
V
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
--------------------------------------------------------------
E
L
T
D
T
P
R
V
A
T
A
G
E
P
N
F
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
88.95
100%
-75
- C3 -
4XWP
1
ESPB_MYCTU
A:
[4-275]
------
V
T
V
D
Q
Q
E
I
------
L
N
R
A
N
E
V
E
A
P
M
A
D
P
P
T
D
V
---
P
I
-
T
P
--
C
E
L
T
A
A
--
K
N
A
A
Q
Q
L
-----------
V
L
S
A
D
N
M
R
E
Y
L
A
A
------
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
A
K
A
Y
G
E
V
D
-----------------------------------------------------------
L
T
D
T
P
R
V
A
T
------
M
D
L
K
E
A
A
R
K
L
E
T
G
D
-
Q
-
G
A
S
-
L
A
H
F
A
D
G
W
N
T
F
N
---
L
T
L
Q
G
-------
D
V
-
K
R
F
R
-----
G
-
F
-----
D
N
W
E
G
D
A
A
T
A
C
E
A
S
L
D
Q
Q
R
Q
------------------
W
I
L
-
H
M
A
K
L
S
A
A
M
A
K
Q
A
Q
Y
V
A
Q
L
H
V
W
A
R
R
E
H
P
T
Y
E
D
I
V
G
L
E
R
--
L
Y
A
E
N
---------
P
---------
S
A
R
D
Q
------------
I
L
P
V
Y
A
E
Y
-----
Q
Q
R
S
E
K
V
L
T
E
Y
N
N
K
--
A
A
L
----------
E
P
V
N
P
P
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
62.26
27%
-45
- C3 -
4WJ2
-
?
A:
[12-281]
-------------
L
------
E
R
K
A
H
E
C
E
S
T
R
P
E
G
P
G
D
A
----
T
-
K
P
--
D
E
L
A
T
T
--
A
S
V
Y
S
K
L
-----------
M
A
S
A
A
K
L
K
A
T
F
A
A
------
G
D
R
E
G
E
R
I
A
A
A
I
R
A
A
A
G
A
Y
Q
K
I
E
E
Q
K
A
A
E
L
-----
S
----------------A
E
A
V
V
P
D
M
S
G
-------
I
P
G
P
L
A
I
-----
P
S
M
E
Y
P
S
A
-----
E
--
M
D
W
E
A
A
A
R
I
I
H
S
G
D
T
Q
-
A
L
S
-
M
K
Y
F
R
D
Q
W
R
D
Y
Q
---
S
T
L
E
G
-------
H
G
-
R
H
F
A
-----
N
P
A
-----
E
G
W
A
G
A
A
A
E
T
C
A
E
A
Q
R
R
L
S
T
------------------
W
W
A
-
D
M
G
A
E
C
G
R
L
A
Q
E
A
T
T
F
V
D
A
H
D
K
L
V
A
N
H
P
T
L
E
N
V
R
E
F
E
E
--
T
E
W
A
S
---------
E
---------
W
D
R
Q
N
---------------
A
W
A
M
L
-----
Q
E
Q
S
E
D
A
L
E
A
Y
A
N
G
--
S
Q
I
----------
Q
E
I
R
P
G
K
P
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
48.38
13%
-44
- C3 -
4W4K
-
PPE41_MYCTU
B:
[5-170]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
P
P
E
V
N
S
A
N
I
Y
A
G
P
-
G
-
P
D
S
-
M
L
A
A
A
R
A
W
R
S
L
D
---
V
E
M
T
A
-------
V
Q
-
R
S
F
N
R
T
L
L
S
L
-
M
-----
D
A
W
A
G
P
V
V
M
Q
L
M
E
A
A
K
P
F
V
R
------------------
W
L
T
-
D
L
C
V
Q
L
S
E
V
E
R
Q
I
H
E
I
V
R
A
Y
E
W
A
H
H
D
M
V
P
L
A
Q
I
Y
N
N
R
A
--
E
R
Q
I
L
I
D
N
NALGQF
T
---------
A
Q
I
A
D
------------
L
D
Q
E
Y
D
D
F
-----
W
D
E
D
G
E
V
M
R
D
Y
R
L
R
--
V
S
D
A
L
--------
S
K
L
T
P
W
K
A
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
47.37
14%
-34
- C3 -
4KXR
-
PPE41_MYCTU
B:
[1-174]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
F
E
A
Y
P
P
E
V
N
S
A
N
I
Y
A
G
P
-
G
-
P
D
S
-
M
L
A
A
A
R
A
W
R
S
L
D
---
V
E
M
T
A
-------
V
Q
-
R
S
F
N
-----
R
-
T
L
L
S
L
M
D
A
W
A
G
P
V
V
M
Q
L
M
E
A
A
K
P
F
V
R
------------------
W
L
T
-
D
L
C
V
Q
L
S
E
V
E
R
Q
I
H
E
I
V
R
A
Y
E
W
A
H
H
D
M
V
P
L
A
Q
I
Y
N
N
R
A
--
E
R
Q
I
L
---------
I
D
N
NALGQF
T
A
Q
I
A
D
------------
L
D
Q
E
Y
D
D
F
-----
W
D
E
D
G
E
V
M
R
D
Y
R
L
R
V
S
D
A
L
----------
S
K
L
T
P
W
K
A
P
P
P
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
44.94
11%
-41
- C3 -
2G38
1
PPE41_MYCTU
B:
[5-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
P
P
E
V
N
S
A
N
I
Y
A
G
P
-
G
-
P
D
S
-
M
L
A
A
A
R
A
W
R
S
L
D
---
V
E
M
T
A
-------
V
Q
-
R
S
F
N
R
T
L
LS
L
-
M
-----
D
A
W
A
G
P
V
V
M
Q
L
M
E
A
A
K
P
F
V
R
------------------
W
L
T
-
D
L
C
V
Q
L
S
E
V
E
R
Q
I
H
E
I
V
R
A
Y
E
W
A
H
H
D
M
V
P
L
A
Q
I
Y
N
N
R
A
--
E
R
Q
I
L
I
D
N
NALGQF
T
---------
A
Q
I
A
D
------------
L
D
Q
E
Y
D
D
F
-----
W
D
E
D
G
E
V
M
R
D
Y
R
L
R
--
V
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
36.36
19%
2
- C2 -
4YPL
1
?
C:
[5-542]
L
S
D
L
E
A
L
R
K
K
I
E
E
V
GMPEAV
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
---
P
-------
E
A
T
V
A
--
R
T
Y
L
D
W
L
TEVPWSKADPE
V
L
D
I
N
H
T
R
Q
V
L
D
E
DHYGLK
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
D
V
R
N
K
A
P
I
L
V
L
-----
V
--
G
P
P
----------
G
---
V
G
K
T
S
L
G
R
------
S
I
A
R
S
M
N
-------
R
K
F
H
R
I
S
L
G
G
V
R
D
E
A
E
I
R
G
H
R
R
T
Y
I
G
A
M
-
P
-
G
K
L
-
I
H
A
M
K
Q
V
G
V
I
N
P
---
V
I
L
L
D
-------
Q
I
-
D
K
M
S
-----
S
--------
D
W
R
G
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
NTFTDHYLDVPYDLSKVF
F
I
T
-
T
A
N
T
L
Q
T
I
P
R
P
L
L
D
R
M
E
V
I
E
I
----
P
G
Y
T
N
M
E
K
Q
A
I
A
R
--
Q
Y
L
W
P
---------
K
---------
Q
V
R
E
S
GMEGRIEVTDAA
I
L
R
V
I
S
E
Y
TREAG
V
R
G
L
E
R
E
L
G
K
I
A
R
K
--
G
A
K
FWLEGAWEGL
R
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
AETEP
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
HTQDYGLP
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
-
D
I
A
M
T
G
E
V
-
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
AGIHKIVLPK
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
L
P
E
P
T
M
P
P
VV
7
PsiBlast_PDB
36.19
26%
26
- C3 -
4WJ1
-
?
A:
[12-281]
-------------
L
------
E
R
K
A
H
E
C
E
S
T
R
P
E
G
P
G
D
A
----
T
-
K
P
--
D
E
L
A
T
T
--
A
S
V
Y
S
K
L
-----------
M
A
S
A
A
K
L
K
A
T
F
A
A
------
G
D
R
E
G
E
R
I
A
A
A
I
R
A
A
A
G
A
Y
Q
K
I
E
E
Q
K
A
A
E
L
-----
S
R
Q
M
N
G
----------
S
D--
A
P
P
P
A
A
E
A
------
V
V
P
D
M
S
G
IP
G
P
L
A
I
P
S
M
E
Y
P
S
A
A
A
A
A
D
E
M
D
W
E
A
A
A
R
I
I
H
S
G
D
T
Q
-
A
L
S
-
M
K
Y
F
R
D
Q
W
R
D
Y
Q
---
S
T
L
E
G
-------
H
G
-
R
H
F
A
-----
N
P
A
-----
E
G
W
A
G
A
A
A
E
T
C
A
E
A
Q
R
R
L
S
T
------------------
W
W
A
-
D
M
G
A
E
C
G
R
L
A
Q
E
A
T
T
F
V
D
A
H
D
K
L
V
A
N
H
P
T
L
E
N
V
R
E
F
E
E
--
T
E
W
A
S
---------
E
---------
W
D
R
Q
N
---------------
A
W
A
M
L
-----
Q
E
Q
S
E
D
A
L
E
A
Y
A
N
G
--
S
Q
I
----------
Q
E
I
R
P
G
K
P
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
34.49
25%
25
- C3 -
4WJ1
-
?
A:
[3-286]
----
E
E
L
Q
Y
E
L
P
G
L
------
E
R
K
A
H
E
C
E
S
T
R
P
E
G
-
P
G
D
---
A
T
-
K
P
--
D
E
L
A
T
T
--
A
S
V
Y
S
K
L
-----------
M
A
S
A
A
K
L
K
A
T
F
A
A
------
G
D
R
E
G
E
R
I
A
A
A
I
R
A
A
A
G
A
Y
Q
K
I
E
E
Q
K
A
A
E
L
-----
S
R
Q
M
N
G
----------
S
---
D
A
P
P
P
A
A
E
A
V
V
P
DM
S
G
I
P
G
P
L
-----
A
I
P
S
M
E
Y
P
S
A
A
A
A
A
D
E
M
D
W
E
A
A
A
R
I
I
H
S
G
D
-
T
Q
A
L
S
-
M
K
Y
F
R
D
Q
W
R
D
Y
Q
---
S
T
L
E
G
-------
H
G
R
H
F
A
N
-----
P
-
A
-----
E
G
W
A
G
A
A
A
E
T
C
A
E
A
Q
R
R
L
S
T
------------------
W
W
A
-
D
M
G
A
E
C
G
R
L
A
Q
E
A
T
T
F
V
D
A
H
D
K
L
V
A
N
H
P
T
L
E
N
V
R
E
F
E
E
TE
W
A
S
E
-----------------------
W
D
------------
R
Q
N
A
W
A
M
L
-----
Q
E
Q
S
E
D
A
L
E
A
Y
A
N
G
--
S
Q
I
----------
Q
E
I
R
P
G
K
P
P
S
I
G
G
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
33.12
20%
14
- C3 -
3FAV
3
ESXB_MYCTU
A:
[12-85]
-------------
L
------
A
Q
E
A
G
N
F
E
R
I
S
G
D
L
K
T
Q
I
D
Q
V
E
S
-
T
A
--
G
S
L
Q
G
Q
WR
G
A
A
G
T
A
A
-----------
Q
A
A
V
V
R
F
Q
E
A
A
N
K
------
Q
K
Q
E
L
D
E
I
S
T
N
I
R
Q
A
G
V
Q
Y
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
32.09
14%
14
- C3 -
4WHE
1
PSPA_ECOLI
A:
[3-142]
-------------
I
------
F
S
R
F
A
D
I
V
N
A
N
I
N
A
--------
L
-
L
E
--
D
P
Q
K
L
V
--
R
L
M
I
Q
E
M
-----------
E
D
T
L
V
E
V
R
S
T
S
A
R
------
A
L
A
E
K
K
Q
L
T
R
R
I
E
Q
A
S
A
R
E
V
E
W
Q
E
K
A
E
L
A
L
L
K
ER
E
D
L
A
R
A
A
----------
L
---
I
E
K
Q
K
L
T
D
------
L
I
K
S
L
E
H
-----
E
V
T
L
V
D
D
T
L
A
R
M
K
K
E
I
G
E
L
E
N
K
L
S
E
T
R
A
R
Q
-
Q
-
A
L
M
-
L
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
30.67
10%
9
- C3 -
2G38
1
PPE41_MYCTU
B:
[2-174]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
E
A
Y
P
P
E
V
N
S
A
N
I
Y
A
G
P
-
G
-
P
D
S
-
M
L
A
A
A
R
A
W
R
S
L
D
---
V
E
M
T
A
-------
V
Q
-
R
S
F
N
-----
R
-
T
L
LSLM
D
A
W
A
G
P
V
V
M
Q
L
M
E
A
A
K
P
F
V
R
------------------
W
L
T
-
D
L
C
V
Q
L
S
E
V
E
R
Q
I
H
E
I
V
R
A
Y
E
W
A
H
H
D
M
V
P
L
A
Q
I
Y
N
N
R
A
--
E
R
Q
I
L
---------
I
---------
D
N
N
A
L
------------
G
Q
F
T
A
Q
I
A
-----
D
L
D
Q
E
Y
D
D
F
W
D
E
D
G
--
E
V
M
----------
R
D
Y
R
L
R
V
S
D
A
L
S
K
L
T
P
W
K
A
P
P
-----
P
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
29.97
13%
-4
- C3 -
4WPC
1
RGD1_YEAST
A:
[14-310]
------------------------------
F
S
T
P
E
I
K
K
---
V
L
N
S
D
--
V
A
I
N
A
L
--
L
S
R
L
K
Q
S
-----------
L
L
T
C
E
E
F
M
K
F
I
R
K
------
K
Y
A
F
E
E
E
H
V
Q
E
L
S
K
Q
Y
K
H
F
F
N
I
Q
N
S
S
L
K
K
M
-----
I
H
E
V
L
G
F
D
G
K
M
A
Q
V
K
Q
S
---
Y
I
T
A
L
Q
K
M
------
Y
S
E
I
S
S
L
-----
L
L
T
M
T
K
L
R
K
S
V
K
E
N
S
K
R
L
E
K
D
V
S
D
A
I
H
S
A
E
-
K
-
A
Q
S
R
Y
N
S
L
C
Q
D
W
D
K
L
R
KTK
L
T
L
R
G
S
K
T
T
K
E
Q
E
E
-
E
L
L
R
-----
K
-
I
-----
D
N
A
D
L
E
Y
K
Q
K
V
D
H
S
N
S
L
R
N
T
------------------
F
I
T
K
E
R
P
R
I
V
Q
E
L
K
D
L
I
L
E
I
D
T
A
M
T
I
Q
L
Q
K
Y
T
I
W
T
E
N
L
V
L
N
T
--
G
V
T
I
S
---------
P
---------
L
D
S
T
K
------------
S
M
K
S
F
A
G
------
S
V
S
N
E
R
D
L
Y
S
F
L
N
K
--
Y
N
-----------
Q
L
I
N
K
N
L
I
P
V
S
Y
K
K
H
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
28.54
11%
21
- C3 -
3ZBH
3
?
A:
[9-98]
--------
L
T
P
E
E
L
------
R
G
V
A
R
Q
Y
N
V
E
S
S
N
V
T
E
L
I
---
A
R
L
D
Q
M
S
H
T
L
Q
G
I
WE
G
A
S
S
E
A
F
-----------
I
Q
Q
Y
Q
E
L
R
P
S
F
E
K
------
M
A
V
L
L
N
E
V
G
Q
Q
L
H
N
S
A
T
I
L
E
D
T
D
Q
Q
I
A
S
Q
I
-----
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------