@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3896c: (2016-05-24 )
MSTWHRIGTEGEPLTDPLTTQAIAALSRGHGLFAGGVSGADIDAPQIQQYANAISWVANAVPTAAAYRWRGAARALRRLANTDEALAQIMAAAQIDHAHARTATRALLEAAKTDAMALTDTPLGRREAMARMAARLRAQHRHIARCRSRARLLGLRLRRLRYLRTAAARRPQVTTPGGRAQVLAAIQKALDIQGVHDPAARARWTRGMDLVARRESNYNANAINHWDSNAARGTPSRGVWQFIAPTFAAYHEPGTSTNIHDLVAQACAFINYARGHYGVAADASNLADLIQQADPRRSPRGY
Atome Classification :
(20 SA)
.........10......---..20........30......---..40........50---........60-.........70........80.---.......90......-..100.......110.---......120..-.....130.-......140.......150.......160.......170.......180.......190.......200.......210....---...220...-----------------------------------.-----------------------------------...230...-----......240.....-----..----250--..--.---------------.---...260.......----.270.......280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
T
W
HRIGTEGEPLTD
P
---
L
T
T
Q
A
I
A
A
L
SRGH
G
L
F
AGGV---SGADI
D
A
P
Q
I
Q
Q
Y
A
---
N
A
I
S
W
V
A
NA--VPT
A
A
A
Y
R
W
R
G
A
A
R
A
L
R
R
LA
N
T
---
D
E
A
L
A
Q
I
M
A
A
A
QID
H
-
A
H
A
R
T
A
T
R
A
L
L
E
A
AKT---D
A
M
A
LTDTPL
G
-
R
R
E
A
M
A
R
M
A
-
A
R
L
R
A
Q
H
R
H
I
A
R
C
R
S
R
A
R
L
L
G
L
R
L
R
R
L
R
Y
L
R
T
A
AARRPQVTTPG
G
R
A
Q
V
L
A
A
I
Q
K
A
LDIQGVHD
P
A
A
R
A
R
W
TR
G
M
D
L
V
A
RRES---NYNANAINH-----------------------------------W-----------------------------------DSNA--ARG-----TPSR
G
V
W
Q
F
I
A
P
T
F
-----
A
A
----YHE--PG--T---------------S---T
N
I
H
-
D
L
V
A
Q
A
C
A
----
F
I
NYARGHYGVAA
D
A
S
N
L
A
D
L
I
Q
QADPRRSPRGY
39
Fugue
61.71
17%
-30
- C2 -
2W1N
1
A:
[10-237]
-----------
A
E
V
T
G
S
---
V
S
L
E
A
L
E
E
V
Q
V
G
E
-
N
I
E
V
G
V
---
G
I
D
E
L
V
N
A
E
A
F
A
Y
D
---
F
T
L
N
Y
D
E
N
A
--
F
E
Y
V
E
A
I
S
D
D
G
-------------------
V
F
V
N
A
K
K
I
E
D
-
G
K
V
R
V
L
V
S
S
L
--------------
T
G
E
P
L
P
-
A
K
E
V
L
A
K
V
V
-
L
R
A
E
A
K
T
E
G
---------------
S
N
L
S
V
T
N
S
S
V
G
------
D
G
E
G
L
V
H
E
I
A
G
T
E
K
T
V
N
I
I
E
G
T
S
P
E
I
V
V
N
P
V
R
--
D
F
K
A
S
E
I
N
---
K
K
N
V
T
V
T
W
T
-----------------------------------------------------------------------
E
P
E
T
--
T
E
G
-----
L
E
G
Y
I
L
Y
K
-
D
G
K
K
V
-----
A
E
----
I
G
K
--
D
E
--
T
---------------
S
---
Y
T
F
K
-
K
L
N
-----------
R
H
T
I
Y
N
F
K
I
A
A
K
Y
S
N
G
E
V
S
S
K
E
S
L
T
L
R
T
A
---
16
HHSearch
61.30
18%
-55
- C3 -
1QUS
3
MLTB_ECOLI
A:
[94-223]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
W
N
Q
Y
E
D
A
L
N
R
A
W
Q
V
Y
G
V
P
P
--------
E
I
I
V
G
I
I
G
V
E
T
---
R
W
G
R
V
M
G
K
T
R
I
L
D
A
L
A
T
L
S
F
NYPRR
A
E
Y
F
S
G
E
L
E
T
F
L
L
M
A
R
D
E
Q
D
-----------------------------------
D
P
L
N
L
K
G
S
F
-----
A
G
A
M
G
Y
G
Q
F
M
P
S
S
Y
-----
K
Q
----
Y
A
V
--
D
F
--
S
---------------
G
DGH
I
N
L
W
-
D
P
V
D
A
I
G
S
----
V
A
N
Y
F
K
A
---------------------------
17
HHSearch
60.55
16%
-66
- C3 -
4CFP
3
MLTC_ECOLI
A:
[170-257]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
H
K
Y
L
G
M
V
R
Q
A
S
R
K
Y
G
V
D
E
--------
S
L
I
L
A
I
M
Q
T
Q
S
---
S
F
N
P
Y
A
V
S
R
-------------------------------------------------------------------------------------
S
D
A
L
G
L
M
Q
V
V
Q
H
T
A
-----
G
K
----
D
V
F
R
S
Q
G
--
K
S
G
T
P
S
----------
R
---
S
F
L
F
-
D
P
A
S
N
I
D
T
----
G
T
A
Y
L
A
----------------------------
19
HHSearch
60.48
20%
-64
- C3 -
4HJZ
1
EMTA_ECOLI
A:
[38-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
M
Q
W
M
P
I
S
Q
K
A
G
A
A
W
G
V
D
P
--------
Q
L
I
T
A
I
I
A
I
Q
S
---
G
G
N
P
N
A
V
S
K
-------------------------------------------------------------------------------------
S
N
A
I
G
L
M
Q
L
K
A
S
T
S
G
R
D
V
Y
R
R
----
M
G
W
--
S
G
E
P
T
---------------
T
---
S
E
L
K
-
N
P
E
R
N
I
S
M
----
G
A
A
Y
L
N
I
L
--------------------------
18
HHSearch
59.07
18%
-54
- C3 -
4ANR
1
?
A:
[89-222]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
W
N
K
H
A
E
D
L
A
R
A
E
K
E
Y
G
V
P
A
--------
E
I
I
V
S
I
I
G
V
E
T
---
F
F
G
R
N
T
G
S
Y
-----------------------------------
R
V
M
D
A
L
S
T
L
G
F
DYPPR
A
D
F
F
R
K
E
L
R
E
F
L
L
L
A
R
E
Q
QV
D
P
L
S
L
T
G
S
Y
-----
A
G
A
M
G
L
P
Q
F
M
P
S
S
F
-----
R
A
----
Y
A
V
--
D
F
--
D
---------------
G
DGH
I
N
I
W
S
D
P
T
D
A
I
G
S
----
V
A
S
Y
F
K
Q
---------------------------
21
HHSearch
57.73
16%
-65
- C3 -
4P0G
3
MLTF_PSEAE
A:
[264-339]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
Y
E
S
H
F
K
Q
S
G
K
Q
L
D
T
D
W
--------
R
L
L
A
A
I
G
Y
Q
E
S
---
L
W
Q
P
G
A
T
S
K
-------------------------------------------------------------------------------------
T
G
V
R
G
L
M
M
L
T
N
R
T
A
-----
Q
A
----
M
G
V
--------------------------
S
N
R
L
-
D
P
K
Q
S
I
Q
G
----
G
S
K
Y
F
V
Q
---------------------------
35
Fugue
57.45
12%
-63
- C4 -
1QWG
3
PSLS_METJA
A:
[1-251]
-------
M
K
A
F
E
F
L
Y
E
D
---
F
Q
R
G
L
T
V
V
L
D
K
G
-----------
L
P
P
K
F
V
E
D
Y
L
K
V
C
G
---
D
Y
I
D
F
V
K
F
G
--
W
G
T
S
A
V
I
D
R
D
V
V
K
E
K
I
N
Y
Y
K
D
W
---
G
--
I
K
V
Y
P
G
G
T
L
F
E
Y
-
A
Y
S
K
G
K
F
D
E
F
L
N
E
C
E
K
L
GF
E
A
V
E
I
S
D
G
S
S
D
I
S
L
E
E
R
N
N
A
I
-
K
R
A
K
D
N
G
-------------------
F
M
V
L
T
E
V
G
K
K
M
P
D
K
D
K
Q
L
T
I
D
D
R
I
K
L
I
N
F
D
L
D
A
-
G
A
D
Y
V
I
I
E
G
R
E
S
G
K
G
K
G
L
F
D
K
E
G
---
K
V
K
E
N
E
L
D
V
-----------------------------------
L
-----------------------------------
A
K
N
V
--
D
I
N
K
V
I
F
E
A
P
Q
K
S
Q
Q
V
A
F
I
L
K
F
-----------------
G
--
S
---------------
S
---
V
N
L
A
-
N
I
A
F
D
E
V
I
----
S
L
E
T
L
R
R
G
L
R
G
D
T
F
G
K
V
-----------------
42
Fugue
55.81
19%
-75
* C4 *
3F2E
1
?
A:
[8-90]
----------------------------------------------------
F
T
A
V
A
---
E
Q
V
S
A
V
L
S
Q
Y
G
I
T
G
P
N
R
A
I
Y
Q
G
F
G
L
K
V
A
R
A
L
N
R
LGG
G
P
A
L
V
N
M
I
N
G
L
K
A
Y
Y
-
I
S
A
F
N
A
N
P
T
V
L
D
A
V
------
T
D
I
I
T
G
S
P
T
G
-
Y
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
55.32
15%
-57
* C3 *
1QSA
5
SLT_ECOLI
A:
[449-536]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
L
A
Y
N
D
L
F
K
R
Y
T
S
G
K
E
I
P
Q
--------
S
Y
A
M
A
I
A
R
Q
E
S
---
A
W
N
P
K
V
K
S
P
-------------------------------------------------------------------------------------
V
G
A
S
G
L
M
Q
I
M
P
G
T
A
-----
T
H
T
V
K
M
F
S
I
--
P
G
YS
S
---------------
P
---
G
Q
L
L
-
D
P
E
T
N
I
N
I
----
G
T
S
Y
L
Q
Y
---------------------------
43
Fugue
51.24
19%
-22
- C1 -
2E2E
2
NRFG_ECO57
A:
[2-177]
--
K
W
Q
A
V
R
A
E
Y
Q
R
Q
R
D
P
---
L
H
Q
F
A
E
A
Q
L
Q
A
L
Q
D
K
I
R
A
N
P
---
Q
----
N
S
E
Q
W
A
L
L
G
---
E
Y
Y
L
W
Q
N
D
Y
--
S
N
S
L
L
A
Y
R
-----
Q
A
L
Q
L
R
G
E
N
---
A
E
L
Y
A
A
L
A
T
V
L
Y
Y
Q
A
S
Q
H
M
T
A
Q
T
R
A
M
I
D
K
A
L
A
---
L
-------
D
S
N
-
E
I
T
A
L
M
L
L
A
-
S
D
A
F
M
Q
A
N
Y
A
Q
A
I
E
L
W
Q
K
V
M
D
L
N
S
P
R
I
N
-----------------
R
T
Q
L
V
E
S
I
N
M
A
K
L
L
Q
R
R
S
D
L
E
H
H
H
H
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
49.61
15%
-55
- C3 -
2VB1
12
LYSC_CHICK
A:
[8-97]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
A
M
K
R
H
G
L
D
N
--
Y
R
G
Y
S
L
G
N
W
V
C
A
A
K
F
E
S
---
N
F
N
T
Q
A
T
N
R
-----------------------------------
N
-----------------------------------------
T
D
G
-----
S
T
D
Y
G
I
L
Q
I
N
S
R
W
W
-----
C
N
----
D
G
R
--
T
P
G-
S
---------------
R
---
N
L
C
N
-
I
P
C
S
A
L
L
S
SDI
T
A
S
V
N
C
A
K
K
--------------------------
23
HHSearch
48.24
13%
-34
- C3 -
4M5E
3
?
A:
[221-328]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
P
S
R
A
K
V
M
S
A
A
A
R
K
Y
D
L
T
P
--------
Q
L
I
G
A
I
I
L
A
E
Q
R
D
Q
T
R
D
E
D
A
K
D
Y
-----------------------------------
Q
A
----------------------------------
A
V
S
I
--
K
S
A
-----
N
T
S
I
G
L
G
Q
V
V
V
S
T
A
-----
I
K
----
Y
E
L
--
F
T
--
D
LLG
Q
P
V
R
R
G
LS
R
K
A
V
A
---
T
L
L
A
-
S
D
E
F
N
I
F
A
----
T
A
R
Y
I
R
----------------------------
36
Fugue
47.93
16%
-27
- C3 -
1QU1
-
?
A:
[34-175]
---------------------------------------------
Q
A
A
D
L
K
S
T
Q
A
A
I
---
D
Q
I
N
G
K
L
N
R
--
V
I
E
K
T
N
E
K
F
H
Q
I
E
K
E
F
S
E
V
E
G
R
---
I
Q
D
L
E
K
Y
V
E
D
T
K
I
D
L
-
W
S
Y
N
A
E
L
L
V
A
L
E
N
Q
H
T
-----
I
D
L
T
D
S
E
M
N
-
K
L
F
E
K
T
R
R
Q
L
G
S
F
K
I
Y
H
K
C
D
N
A
C
I
E
S
I
R
N
G
--
T
Y
D
H
D
V
Y
R
D
E
A
L
N
N
R
F
Q
I
K
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
47.43
17%
-31
- C3 -
1LSG
-
LYSC_CHICK
A:
[9-96]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
A
M
K
R
H
G
L
D
N
--
Y
R
G
Y
S
L
G
N
W
V
C
A
A
K
F
E
S
---
N
F
N
T
Q
A
T
N
R
-----------------------------------
N
-----------------------------------------
T
D
G
-----
S
T
D
Y
G
I
L
Q
I
N
S
R
W
W
-----
C
N
----
D
G
R
--
T
P
--
G
---------------
S
R--
N
L
C
N
-
I
P
C
S
A
L
L
S
SDI
T
A
S
V
N
C
A
----------------------------
6
PsiBlast_PDB
46.41
30%
-7
- C3 -
1OBC
1
?
A:
[617-710]
-----
K
M
G
A
E
L
R
P
H
E
D
G
T
L
H
L
W
K
P
A
V
M
S
K
S
K
G
N
G
V
M
V
G
P
F
V
K
E
Q
G
A
D
I
A
R
I
T
I
L
F
A
A
PPE
N
E
M
V
W
T
E
E
G
--
V
Q
G
A
----
W
R
F
L
N
R
I
Y
R
R
V
A
E
D
---
R
E
A
L
L
E
T
S
G
V
F
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
46.31
30%
-10
- C3 -
2V0C
2
?
A:
[617-710]
-----
K
M
G
A
E
L
R
P
H
E
D
G
T
L
H
L
W
K
P
A
V
M
S
K
S
K
G
N
G
V
M
V
G
P
F
V
K
E
Q
G
A
D
I
A
R
I
T
I
L
F
A
A
PPE
N
E
M
V
W
T
E
E
G
--
V
Q
G
A
----
W
R
F
L
N
R
I
Y
R
R
V
A
E
D
---
R
E
A
L
L
E
T
S
G
V
F
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.80
30%
-9
- C3 -
1H3N
2
?
A:
[617-710]
-----
K
M
G
A
E
L
R
P
H
E
D
G
T
L
H
L
W
K
P
A
V
M
S
K
S
K
G
N
G
V
M
V
G
P
F
V
K
E
Q
G
A
D
I
A
R
I
T
I
L
F
A
A
PPE
N
E
M
V
W
T
E
E
G
--
V
Q
G
A
----
W
R
F
L
N
R
I
Y
R
R
V
A
E
D
---
R
E
A
L
L
E
T
S
G
V
F
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
45.78
11%
-48
- C3 -
4G9S
1
?
A:
[45-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
M
N
K
Y
K
E
L
I
T
R
V
G
Q
K
H
G
L
D
P
--------
A
I
I
A
G
I
I
S
R
E
S
---
R
A
G
S
A
L
D
H
G
-----------------------------------
W
-----------------------------------------
G
D
H
-----
G
K
G
F
G
L
M
Q
V
D
K
R
Y
H
-----
K
I
----
V
-----------------------------
G
A
W
-
D
S
E
K
H
I
S
Q
----
G
T
E
I
L
I
E
---------------------------
3
PsiBlast_PDB
45.15
30%
-15
- C3 -
2BTE
3
?
A:
[617-710]
-----
K
M
G
A
E
L
R
P
H
E
D
G
T
L
H
L
W
K
P
A
V
M
S
K
S
K
G
N
G
V
M
V
G
P
F
V
K
E
Q
G
A
D
I
A
R
I
T
I
L
F
A
A
PPE
N
E
M
V
W
T
E
E
G
--
V
Q
G
A
----
W
R
F
L
N
R
I
Y
R
R
V
A
E
D
---
R
E
A
L
L
E
T
S
G
V
F
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.06
30%
-8
- C3 -
1OBH
3
?
A:
[617-710]
-----
K
M
G
A
E
L
R
P
H
E
D
G
T
L
H
L
W
K
P
A
V
M
S
K
S
K
G
N
G
V
M
V
G
P
F
V
K
E
Q
G
A
D
I
A
R
I
T
I
L
F
A
A
PPE
N
E
M
V
W
T
E
E
G
--
V
Q
G
A
----
W
R
F
L
N
R
I
Y
R
R
V
A
E
D
---
R
E
A
L
L
E
T
S
G
V
F
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------