@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0004: (2015-12-17 )
MSENNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNSIDEALAGYCSEISITIHTDESITVRDNGRGIPVDIHKEEGVSAAEVIMTVLHAGGKFDDNTYKVSGGLHGVGVSVVNALSHELRLTIRRHNKVWEQVYHHGVPQFPLREVGETDGSGTEVHFKPSPETFSNIHFSWDILAKRIRELSFLNSGVGILLRDERTGKEELFKYEGGLKAFVEYLNTNKTAVNEVFHFNVQREEDGVGVEVALQWNDSFNENLLCFTNNIPQRDGGTHLAGFRSALTRNLNNYIEAEGLAKKFKIATTGDDAREGLTAIISVKVPDPKFSSQTKDKLVSSEVKTAVEQEMGKYFADFLLENPNEAKAVVGKMIDAARAREAARKAREMTRRKGALDIAGLPGKLADCQEKDPALSELYIVEGDSAGGSAKQGRNRRTQAILPLKGKILNVEKARFDKMLSSQEVGTLITALGCGIGREEYNIDKLRYHNIIIMTDADVDGSHIRTLLLTFFFRQMPELIERGYIYIAQPPLYKVKRGKQEQYIKDDQAMEEYMTQSALEDASLHVNEHAPGLSGAALEKLVNEYRGVIATLKRLSRLYPQELTEHFIYLPTVSVDDLANESAMQGWLEKFQARLTAAEKSGLTYKASLREDRERHLWLPEVELVAHGLSSYVTFNRDFFASNDYRSVSLLGDQLNSLLEDGAYVQKGERKRPISAFKDGLDWLMAEGTKRHSIQRYKGLGEMNPEQLWETTMDPNVRRMLKVTIEDAIAADQIFNTLMGDAVEPRRDFIESNALAVSNLDV
Atome Classification :
(74 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......-150.....---..160.--.--.--.--.....170......-.180.-.......190.......200.......210-..--------..--..--...220.....-..230......-.240.......250.......260..-.....-270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSENNTYDSS
S
I
K
V
L
K
G
L
D
A
V
R
KRP
G
M
Y
IGDTDDGT
G
L
H
H
M
V
F
E
V
V
D
N
S
I
D
E
A
L
A
G
YC
S
E
I
S
I
T
I
HTD
E
S
I
T
VRDNGRGI
P
V
D
I
HKEEGV
S
A
A
E
V
I
M
T
V
L
HAGGKFDDN
T
Y
K
VSGGLH
G
V
G
V
S
V
V
N
A
L
S
H
E
L
R
L
T
I
R
R
H
N
K
V
W
E
Q
V
Y
HH-GVPQF
P
L
R
---EVG--E--T--D--G--SG
T
E
V
H
FKPSPETF-
S
N
I
-
H
-
F
S
W
D
I
L
A
K
R
I
R
E
L
S
F
L
NSG
V
G
I
L
L
RDER---T
G
--------
K
E
--
E
L
--
F
K
YEG
G
L
K
A
F
V
-
E
Y
LNTN
K
T
A
V
N
-
E
V
F
H
F
N
V
QREEDGV
G
V
E
V
A
L
Q
WNDSF-NE
N
L
L
-
C
FTNNIPQRDGG
T
H
L
A
G
F
R
S
A
L
T
R
N
L
N
N
Y
I
E
A
EGLA
K
K
F
K
I
A
TTGD
D
A
R
EG
L
T
A
I
I
S
V
KVPDPKFS
S
Q
T
K
D
K
L
V
S
S
E
V
K
T
A
V
E
Q
E
M
G
K
Y
F
A
D
F
L
LENP
N
E
A
K
A
V
V
G
K
M
I
D
A
A
R
A
R
E
A
A
R
K
A
R
E
M
T
R
RKGALDIAGLPGKLADCQEKDPAL
S
E
L
Y
I
V
EGDSAGGSAKQGRNRR
T
Q
A
I
LPLK
G
K
I
L
N
V
E
K
A
R
F
D
K
M
L
S
S
Q
E
V
G
T
L
I
T
A
L
GCGIGREEYNID
K
L
R
Y
H
N
I
I
I
M
TDADV
D
G
S
H
I
R
T
L
L
L
T
F
F
F
R
Q
M
P
E
L
I
ERG
Y
I
Y
IAQPP
L
Y
K
V
KRG
K
Q
E
QYIK
D
D
Q
A
M
E
E
Y
M
T
Q
S
ALEDA
S
L
H
VNEHAPGL
S
G
A
A
L
E
K
L
V
N
E
Y
R
G
V
I
A
T
L
K
R
L
S
R
L
Y
P
Q
E
L
T
E
H
F
I
Y
LPTV
S
V
D
D
LA
N
E
S
A
M
Q
G
W
L
E
K
F
Q
A
R
L
T
A
AEKSG
L
T
Y
K
A
S
L
R
ED
R
E
RHLWL
P
E
V
E
L
V
A
H
G
L
S
S
Y
V
T
FNRDFFASNDY
R
S
V
S
L
L
G
D
Q
L
N
S
L
L
EDG
A
Y
VQKGERKR
P
I
S
A
F
K
D
G
L
D
W
L
M
AEGTKRH
S
I
Q
R
Y
KGLGEM
N
P
E
Q
L
W
E
TTMDP
N
V
R
R
M
L
K
V
T
I
E
D
A
I
A
A
D
Q
I
F
N
T
L
MGDAV
E
P
R
R
D
F
I
E
SNALAVSNLDV
3
PsiBlast_PDB
90.02
73%
-70
- C3 -
4WUD
4
GYRB_ECOLI
A:
[3-391]
-----
S
Y
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
-----
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
89.55
73%
-79
- C3 -
4ZVI
3
?
A:
[1-377]
-----------------
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
-------------------
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
-
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.54
73%
-68
- C3 -
4WUB
5
GYRB_ECOLI
A:
[3-391]
-----
S
Y
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
-----
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
89.31
73%
-68
- C3 -
4XTJ
5
GYRB_ECOLI
A:
[3-391]
-----
S
Y
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
-----
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
88.93
73%
-67
- C3 -
4WUC
5
GYRB_ECOLI
A:
[3-391]
-----
S
Y
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
-----
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
88.19
73%
-73
- C3 -
4PRV
2
GYRB_ECOLI
A:
[16-392]
-----------
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
-------------
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
137
Fugue
87.53
73%
-69
- C3 -
1EI1
6
GYRB_ECOLI
A:
[1-391]
---
S
N
S
S
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
------E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
D
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
-
P
N
I
-
F
Y
F
S
T
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136
Fugue
87.50
73%
-68
- C3 -
1EI1
6
GYRB_ECOLI
A:
[1-391]
---
S
N
S
S
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
D
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
-
P
N
I
-
F
Y
F
S
T
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.95
73%
-69
- C3 -
1EI1
6
GYRB_ECOLI
B:
[9-391]
-----------
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
D
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
86.70
73%
-70
- C3 -
4PU9
3
GYRB_ECOLI
A:
[16-394]
-----------
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
-----------
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
86.69
73%
-69
- C3 -
1EI1
5
GYRB_ECOLI
A:
[9-391]
-----------
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
D
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
P
N
I
F
Y
F
S
T
--
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
79.01
42%
-68
- C3 -
3ZKB
3
GYRB_MYCTU
A:
[17-428]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
-----PHK
V
----
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
---
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
78.13
42%
-67
- C3 -
3ZKB
4
GYRB_MYCTU
B:
[17-429]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
-----V-------
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
78.01
42%
-62
- C3 -
3ZKD
3
GYRB_MYCTU
H:
[17-426]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
---
V
T
QK
V
-----
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
---
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
116
HHSearch
77.79
47%
-71
- C3 -
1KIJ
3
?
A:
[7-389]
----------
A
I
R
V
L
K
G
L
E
G
V
R
H
R
P
A
M
Y
I
G
G
T
G
V
-
E
G
Y
H
H
L
F
K
E
I
L
D
N
A
V
D
E
A
L
A
G
Y
A
T
E
I
L
V
R
L
N
E
D
G
S
L
T
V
E
D
N
G
R
G
I
P
V
D
L
M
P
E
E
G
K
P
A
V
E
V
I
Y
N
T
L
H
S
G
G
K
F
E
Q
G
A
Y
K
V
S
G
G
L
H
G
V
G
A
S
V
V
N
A
L
S
E
W
T
V
V
E
V
F
R
E
G
K
H
H
R
I
A
F
S
R
-
G
E
V
T
E
P
L
R
---
V
V
G
EA
P
--
R
--
G
--
K
--
T
G
T
R
V
T
F
K
P
D
P
E
I
F
-
G
N
L
-
R
-
F
D
P
S
K
I
R
A
R
L
R
E
V
A
Y
L
V
A
G
L
K
L
V
F
Q
D
R
Q
---
H
G
--------
K
E
--
E
V
--
F
L
D
K
G
G
V
A
S
F
A
-
K
A
L
A
E
G
E
D
L
L
Y
E
K
P
F
L
I
R
G
T
--
H
G
E
V
E
V
E
V
G
F
L
H
T
Q
G
Y
-
N
A
E
I
L
-
T
Y
A
N
M
I
P
T
R
D
G
G
T
H
L
T
A
F
K
S
A
Y
S
R
A
L
N
Q
Y
A
K
K
A
G
L
N
K
E
K
G
P
Q
P
T
G
D
D
L
L
E
G
L
Y
A
V
V
S
V
K
L
P
N
P
Q
F
E
G
Q
T
K
G
K
L
L
N
P
E
A
G
T
A
V
G
Q
V
V
Y
E
R
L
L
E
I
L
E
E
N
P
R
I
A
K
A
V
Y
E
K
A
L
R
A
A
Q
A
R
E
A
A
R
K
A
R
E
L
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
77.78
42%
-67
- C3 -
3ZKD
3
GYRB_MYCTU
F:
[17-426]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
---
V
T
K
V
------
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
------
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
77.74
42%
-64
- C3 -
3ZKB
4
GYRB_MYCTU
C:
[17-430]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
---
V
-A
P
H
K
V
---
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
77.74
42%
-69
- C3 -
3ZKD
3
GYRB_MYCTU
G:
[17-425]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
---
V
-PHK
V
----
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
----
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
77.41
42%
-66
- C3 -
3ZKB
3
GYRB_MYCTU
D:
[17-427]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
---
V
T
QSTAPHK
V
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
77.41
42%
-66
- C3 -
3ZKD
3
GYRB_MYCTU
D:
[17-428]
------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
T
H
A
S
-
G
I
P
T
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
-
L
G
L
K
---
Q
G
A
--
P
--
T
--
K
--
K
--
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
T
T
-
E
-
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
E
R
---
V
-K
V
------
K
S
--
R
T
--
F
H
Y
P
G
G
L
V
D
F
V
-
K
H
I
N
R
T
K
N
A
I
H
-
S
S
I
-
V
D
F
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
---
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
72.57
36%
-67
- C3 -
1S16
4
PARE_ECOLI
B:
[4-383]
-----
T
Y
N
A
D
A
I
E
V
L
T
G
L
E
P
V
R
R
R
P
G
M
Y
T
----
D
T
T
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
I
H
P
E
E
G
V
P
A
V
E
L
I
L
C
R
L
H
A
G
G
K
F
S
N
K
N
Y
Q
F
S
G
G
L
H
G
V
G
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
-
G
E
K
V
Q
D
L
Q
---
V
V
G
--
T
--
C
--
G
KR
N
--
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
S
P
-
R
-
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
E
I
---
N
N
--------
T
E
--
Q
R
--
W
C
Y
Q
D
G
L
N
D
Y
L
A
E
A
V
N
G
L
P
T
L
P
E
-
K
P
F
I
G
N
F
A
G
D
T
E
--
A
V
D
W
A
L
L
W
L
P
E
G
-
G
E
L
L
T
E
S
Y
V
N
L
I
P
T
M
Q
G
G
T
H
V
N
G
L
R
Q
G
L
L
D
A
M
R
E
F
C
E
Y
R
N
I
L
P
R
-
G
V
K
L
S
A
E
D
I
W
D
R
C
A
Y
V
L
S
V
K
M
Q
D
P
Q
F
A
G
Q
T
K
E
R
L
S
S
R
Q
C
A
A
F
V
S
G
V
V
K
D
A
F
I
L
W
L
N
Q
N
V
Q
A
A
E
L
L
A
E
M
A
I
S
S
A
Q
R
R
--
M
R
A
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
72.02
36%
-67
- C3 -
1S16
4
PARE_ECOLI
A:
[4-383]
-----
T
Y
N
A
D
A
I
E
V
L
T
G
L
E
P
V
R
R
R
P
G
M
Y
T
----
D
T
T
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
I
H
P
E
E
G
V
P
A
V
E
L
I
L
C
R
L
H
A
G
G
K
F
S
N
K
N
Y
Q
F
S
G
G
L
H
G
V
G
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
-
G
E
K
V
Q
D
L
Q
---
V
V
G
--
T
--
C
--
G
KR
N
--
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
S
P
-
R
-
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
E
I
---
N
N
--------
T
E
--
Q
R
--
W
C
Y
Q
D
G
L
N
D
Y
L
A
E
A
V
N
G
L
P
T
L
P
E
-
K
P
F
I
G
N
F
A
G
D
T
E
--
A
V
D
W
A
L
L
W
L
P
E
G
-
G
E
L
L
T
E
S
Y
V
N
L
I
P
T
M
Q
G
G
T
H
V
N
G
L
R
Q
G
L
L
D
A
M
R
E
F
C
E
Y
R
N
I
L
P
R
-
G
V
K
L
S
A
E
D
I
W
D
R
C
A
Y
V
L
S
V
K
M
Q
D
P
Q
F
A
G
Q
T
K
E
R
L
S
S
R
Q
C
A
A
F
V
S
G
V
V
K
D
A
F
I
L
W
L
N
Q
N
V
Q
A
A
E
L
L
A
E
M
A
I
S
S
A
Q
R
R
--
M
R
A
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
117
HHSearch
71.24
36%
-67
- C3 -
1S16
4
PARE_ECOLI
A:
[4-383]
-----
T
Y
N
A
D
A
I
E
V
L
T
G
L
E
P
V
R
R
R
P
G
M
Y
T
D
T
T
R
----
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
I
H
P
E
E
G
V
P
A
V
E
L
I
L
C
R
L
H
A
G
G
K
F
S
N
K
N
Y
Q
F
S
G
G
L
H
G
V
G
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
-
G
E
K
V
Q
D
L
Q
---
V
V
G
--
T
CG
K
--
R
--
N
--
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
S
P
-
R
-
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
E
I
---
N
N
--------
T
E
--
Q
R
--
W
C
Y
Q
D
G
L
N
D
Y
L
-
A
E
A
V
N
G
L
P
T
L
P
E
K
P
F
I
G
N
F
A
--
G
D
T
E
A
V
D
W
A
L
L
W
L
P
E
G
G
E
L
L
T
E
-
S
Y
V
N
L
I
P
T
M
Q
G
G
T
H
V
N
G
L
R
Q
G
L
L
D
A
M
R
E
F
C
E
Y
R
N
I
L
P
R
-
G
V
K
L
S
A
E
D
I
W
D
R
C
A
Y
V
L
S
V
K
M
Q
D
P
Q
F
A
G
Q
T
K
E
R
L
S
S
R
Q
C
A
A
F
V
S
G
V
V
K
D
A
F
I
L
W
L
N
Q
N
V
Q
A
A
E
L
L
A
E
M
A
I
S
S
A
Q
R
R
M
R
A
--
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
68.90
35%
-68
- C3 -
4HYM
1
?
A:
[7-377]
---------
K
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
T
N
I
E
N
P
----
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
I
H
P
E
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
N
------
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
-
G
F
K
T
K
D
L
E
IID
N
V
G
--
K
--
K
--
N
-----
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
D
I
-
K
-
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
E
I
---
K
K
--------
E
K
--
L
T
--
W
H
F
E
T
G
L
K
G
Y
L
-
D
H
K
L
E
A
E
T
L
P
A
-
E
P
F
I
I
D
N
F
S
N
G
D
S
Y
-
L
D
A
V
F
C
W
C
E
D
P
-
S
E
S
I
K
N
S
Y
V
N
L
I
P
T
P
Q
D
G
T
H
V
T
G
L
K
N
G
I
Y
D
A
I
K
A
Y
I
E
K
N
S
-----
N
I
K
I
T
A
N
D
S
F
A
Q
L
N
Y
V
I
S
V
K
I
T
N
P
Q
F
A
G
Q
T
K
E
K
L
S
N
K
D
V
T
N
F
V
A
T
A
V
K
D
L
L
T
I
W
L
N
Q
N
P
D
E
A
R
Q
I
V
E
N
I
S
K
V
A
Q
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
67.53
35%
-74
- C3 -
4HXZ
1
?
A:
[8-378]
----------
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
T
N
I
E
N
P
----
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
I
H
P
E
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
----------
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
-
G
F
K
T
K
D
L
E
IID
N
V
G
--
K
--
K
--
N
-----
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
D
I
-
K
-
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
E
I
---
K
K
--------
E
K
--
L
T
--
W
H
F
E
T
G
L
K
G
Y
L
-
D
H
K
L
E
A
E
T
L
P
A
-
E
P
F
I
I
D
N
F
S
N
G
D
S
Y
-
L
D
A
V
F
C
W
C
E
D
P
-
S
E
S
I
K
N
S
Y
V
N
L
I
P
T
P
Q
D
G
T
H
V
T
G
L
K
N
G
I
Y
D
A
I
K
A
Y
I
E
K
N
S
L
S
V
K
-
N
I
K
I
T
A
N
D
S
F
A
Q
L
N
Y
V
I
S
V
K
I
T
N
P
Q
F
A
G
Q
T
K
E
K
L
S
N
K
D
V
T
N
F
V
A
T
A
V
K
D
L
L
T
I
W
L
N
Q
N
P
D
E
A
R
Q
I
V
E
N
I
S
K
V
A
Q
K
R
I
N
A
D
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
67.52
35%
-72
- C3 -
4KQV
7
?
A:
[7-378]
---------
K
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
T
N
I
E
N
P
----
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
I
H
P
E
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
N
----------
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
-
G
F
K
T
K
D
L
E
II
D
N
V
G
--
K
--
K
--
N
-----
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
D
I
-
K
-
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
E
I
---
K
K
--------
E
K
--
L
T
--
W
H
F
E
T
G
L
K
G
Y
L
-
D
H
K
-----
L
P
A
-
E
P
F
I
I
D
N
F
S
N
G
D
S
Y
-
L
D
A
V
F
C
W
C
-----
E
S
I
K
N
S
Y
V
N
L
I
P
T
P
Q
D
G
T
H
V
T
G
L
K
N
G
I
Y
D
A
I
K
A
Y
I
E
K
N
S
L
S
V
K
-
N
I
K
I
T
A
N
D
S
F
A
Q
L
N
Y
V
I
S
V
K
I
T
N
P
Q
F
A
G
Q
T
K
E
K
L
S
N
K
D
V
T
N
F
V
A
T
A
V
K
D
L
L
T
I
W
L
N
Q
N
P
D
E
A
R
Q
I
V
E
N
I
S
K
V
A
Q
K
R
I
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
59.34
74%
-76
- C3 -
4KFG
3
GYRB_ECOLI
A:
[2-206]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
-----
V
S
A
A
E
V
I
M
T
V
L
-----------
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
59.23
74%
-81
- C3 -
1AJ6
1
GYRB_ECOLI
A:
[11-216]
-------------
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
-----
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-------
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
H
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
58.85
74%
-72
- C3 -
3G7E
1
GYRB_ECOLI
A:
[1-202]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
58.34
74%
-80
- C3 -
4HYP
2
GYRB_ECOLI
D:
[2-205]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
-----
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
58.11
74%
-79
- C3 -
4HYP
2
GYRB_ECOLI
C:
[2-205]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
-----
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
57.44
74%
-75
- C3 -
4DUH
1
GYRB_ECOLI
B:
[12-217]
-------------
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
------------
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
57.34
74%
-73
- C3 -
4DUH
1
GYRB_ECOLI
A:
[15-217]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
H
P
E
E
G
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
--------
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
56.66
74%
-82
- C3 -
4HYP
2
GYRB_ECOLI
A:
[2-205]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
-----
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
56.06
74%
-79
- C3 -
4HYP
2
GYRB_ECOLI
B:
[2-205]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
I
-----
V
S
A
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
55.70
74%
-76
- C3 -
4KFG
3
GYRB_ECOLI
B:
[2-205]
----------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
------
G
V
S
A
A
E
V
I
M
T
V
L
-------
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
---
V
T
G
--
E
--
T
--
E
--
K
--
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
E
-
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
K
R
---
D
G
--------
K
E
--
D
H
--
F
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
54.38
56%
-68
- C3 -
4URM
1
?
A:
[25-231]
-----------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
V
L
H
A
G
G
K
-------------
G
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
54.27
48%
-73
- C3 -
4LPB
1
?
A:
[17-225]
------------
Q
V
L
E
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
G
F
G
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
G
R
G
M
P
T
G
M
H
A
-
M
G
I
P
T
V
E
V
I
F
T
I
L
H
A
-----------------
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
---
K
I
G
--
T
--
A
LK
S
--
K
--
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
T
T
-
D
-
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
K
R
---
T
D
--------
E
A
--
I
E
--
F
H
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
53.80
48%
-74
- C3 -
4MB9
2
?
A:
[17-225]
------------
Q
V
L
E
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
G
F
G
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
G
R
G
M
P
T
G
M
H
A
-
M
G
I
P
T
V
E
V
I
F
T
I
L
H
A
G
------------
G
L
H
G
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
---
K
I
G
--
T
--
A
LK
S
--
K
--
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
T
T
-
D
-
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
K
R
---
T
D
--------
E
A
--
I
E
--
F
H
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
53.58
48%
-75
- C3 -
5BOD
1
?
A:
[17-225]
------------
Q
V
L
E
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
G
F
G
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
G
R
G
M
P
T
G
M
H
A
-
M
G
I
P
T
V
E
V
I
F
T
I
L
H
A
G
------------------
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
---
K
I
G
--
T
--
A
LK
S
--
K
--
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
T
T
-
D
-
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
K
R
---
T
D
--------
E
A
--
I
E
--
F
H
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
53.41
56%
-70
- C3 -
4URM
2
?
C:
[25-231]
-----------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
V
L
H
A
G
----------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
53.33
56%
-69
- C3 -
4URM
1
?
B:
[25-231]
-----------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
V
L
H
A
G
G
K
F
G
------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
PsiBlast_CBE
53.28
55%
-74
- C3 -
4HXW
2
?
A:
[1-207]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
-
G
E
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
F
A
K
S
I
Q
V
I
I
E
P
D
D
S
I
T
V
I
D
D
G
R
G
I
P
V
G
I
Q
A
K
T
G
R
P
A
V
E
T
V
F
T
V
L
-------------------
V
G
S
S
V
V
N
A
L
S
T
S
L
D
V
R
V
Y
K
D
G
K
V
Y
Y
Q
E
Y
R
R
-
G
A
V
V
D
D
L
K
---
V
I
E
--
E
--
T
--
D
--
R
--
H
G
T
T
V
H
F
I
P
D
P
E
I
F
-
T
E
T
-
T
V
Y
D
F
D
K
L
A
T
R
V
R
E
L
A
F
L
N
R
G
L
H
I
S
I
E
D
R
R
---
E
G
--------
Q
E
--
D
K
K
E
Y
H
Y
E
G
L
E
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
53.06
48%
-74
- C3 -
4MBC
1
?
A:
[17-225]
------------
Q
V
L
E
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
G
F
G
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
G
R
G
M
P
T
G
M
H
A
-
M
G
I
P
T
V
E
V
I
F
T
I
L
H
A
-----------------
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
---
K
I
G
--
T
--
A
LK
S
--
K
--
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
T
T
-
D
-
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
K
R
---
T
D
--------
E
A
--
I
E
--
F
H
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
52.91
52%
-76
- C3 -
4BAE
2
GYRB_MYCSM
B:
[4-204]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
F
A
T
R
V
D
V
K
I
H
A
D
G
S
V
E
V
R
D
D
G
R
G
I
P
V
E
M
H
A
T
-
G
M
P
T
I
D
V
V
M
T
Q
L
------------------
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
T
V
L
R
D
G
Y
E
W
F
Q
Y
Y
D
R
-
S
V
P
G
-
K
L
K
---
Q
G
G
--
E
--
T
--
K
--
E
--
T
G
T
T
I
R
F
W
A
D
P
E
I
F
-
E
T
T
-
D
-
Y
N
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
E
L
T
D
E
R
---
D
G
--------
K
H
--
R
V
--
F
H
Y
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
52.66
48%
-72
- C3 -
4EM7
1
?
A:
[17-225]
------------
Q
V
L
E
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
G
F
G
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
G
R
G
M
P
T
G
M
H
A
-
M
G
I
P
T
V
E
V
I
F
T
I
L
H
A
-----------------
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
---
K
I
G
--
T
--
A
LK
S
--
K
--
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
T
T
-
D
-
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
K
R
---
T
D
--------
E
A
--
I
E
--
F
H
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
PsiBlast_CBE
52.58
55%
-70
- C3 -
4KSG
2
?
A:
[1-207]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
-
G
E
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
F
A
K
S
I
Q
V
I
I
E
P
D
D
S
I
T
V
I
D
D
G
R
G
I
P
V
G
I
Q
A
K
T
G
R
P
A
V
E
T
V
F
T
V
L
--------------------
G
S
S
V
V
N
A
L
S
T
S
L
D
V
R
V
Y
K
D
G
K
V
Y
Y
Q
E
Y
R
R
-
G
A
V
V
D
D
L
K
---
V
I
E
--
E
--
T
--
D
--
R
--
H
G
T
T
V
H
F
I
P
D
P
E
I
F
-
T
E
T
-
T
V
Y
D
F
D
K
L
A
T
R
V
R
E
L
A
F
L
N
R
G
L
H
I
S
I
E
D
R
R
---
E
G
--------
Q
E
--
D
K
K
E
Y
H
Y
E
G
L
E
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
PsiBlast_CBE
52.47
55%
-70
- C3 -
4K4O
2
?
A:
[1-207]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
-
G
E
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
F
A
K
S
I
Q
V
I
I
E
P
D
D
S
I
T
V
I
D
D
G
R
G
I
P
V
G
I
Q
A
K
T
G
R
P
A
V
E
T
V
F
T
V
L
--------------------
G
S
S
V
V
N
A
L
S
T
S
L
D
V
R
V
Y
K
D
G
K
V
Y
Y
Q
E
Y
R
R
-
G
A
V
V
D
D
L
K
---
V
I
E
--
E
--
T
--
D
--
R
--
H
G
T
T
V
H
F
I
P
D
P
E
I
F
-
T
E
T
-
T
V
Y
D
F
D
K
L
A
T
R
V
R
E
L
A
F
L
N
R
G
L
H
I
S
I
E
D
R
R
---
E
G
--------
Q
E
--
D
K
K
E
Y
H
Y
E
G
L
E
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
52.08
48%
-72
- C3 -
4MOT
1
?
A:
[17-225]
------------
Q
V
L
E
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
G
F
G
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
G
R
G
M
P
T
G
M
H
A
-
M
G
I
P
T
V
E
V
I
F
T
I
L
H
A
-----------------
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
---
K
I
G
--
T
--
A
LK
S
--
K
--
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
T
T
-
D
-
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
K
R
---
T
D
--------
E
A
--
I
E
--
F
H
Y
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
51.91
56%
-59
- C3 -
4URO
1
GYRB_STAAU
B:
[26-231]
------------------
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
V
--------------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
51.67
56%
-65
- C3 -
4URM
1
?
D:
[26-231]
------------------
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
V
L
H
A
G
----------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
51.48
56%
-64
- C3 -
4URO
1
GYRB_STAAU
A:
[26-231]
------------------
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
V
-------------------
G
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
51.04
51%
-73
- C3 -
4URN
1
?
A:
[17-223]
--------------
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
K
-
R
G
L
H
H
L
V
Y
E
I
V
D
N
S
V
D
E
V
L
N
G
Y
G
N
E
I
D
V
T
I
N
K
D
G
S
I
S
I
E
D
N
G
R
G
M
P
T
G
I
H
K
-
S
G
K
P
T
V
E
V
I
F
T
V
L
-------------------
V
G
A
S
V
V
N
A
L
S
E
W
L
E
V
E
I
H
R
D
G
N
I
Y
H
Q
S
F
K
N
G
G
S
P
S
S
G
L
V
---
K
K
G
--
K
--
T
--
K
--
K
--
T
G
T
K
V
T
F
K
P
D
D
T
I
F
K
A
S
T
-
S
-
F
N
F
D
V
L
S
E
R
L
Q
E
S
A
F
L
L
K
N
L
K
I
T
L
N
D
L
R
---
S
G
--------
K
E
R
Q
E
H
--
Y
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
50.79
56%
-61
- C3 -
4URO
1
GYRB_STAAU
C:
[25-230]
-----------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
---------------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
50.39
56%
-68
- C3 -
4URO
2
GYRB_STAAU
D:
[25-230]
-----------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
------
P
A
V
E
V
I
L
T
V
--------------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
125
HHSearch
49.84
45%
-70
* C3 *
3FV5
1
PARE_ECOLI
A:
[1-201]
----------------
G
L
E
P
V
R
R
R
P
G
M
Y
T
D
T
T
----
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
I
H
P
E
E
G
V
P
A
V
E
L
I
L
C
R
L
---------------------
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
-
G
E
K
V
Q
D
L
Q
---
V
V
G
--
T
C
G
K
--
R
--
N
--
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
S
P
-
R
-
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
E
I
---
N
N
--------
T
E
--
Q
R
--
W
C
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
PsiBlast_CBE
49.48
47%
-60
- C3 -
4P8O
1
GYRB_STAAR
B:
[3-186]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
105
PsiBlast_CBE
49.23
47%
-60
- C3 -
4P8O
1
GYRB_STAAR
A:
[3-186]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
49.17
35%
-70
- C3 -
4HY1
1
?
B:
[8-271]
----------
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
T
N
I
E
N
P
----
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
I
H
P
E
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
------------
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
-
G
F
K
T
K
D
L
E
IID
N
V
G
--
K
--
K
--
N
-----
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
D
I
-
K
-
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
E
I
---
K
K
--------
E
K
--
L
T
--
W
H
F
E
T
G
L
K
G
Y
L
-
D
H
K
L
-
A
E
T
L
P
A
-
E
------------------------
P
-
S
E
S
I
K
N
S
Y
V
N
L
I
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106
PsiBlast_CBE
48.71
48%
-60
- C3 -
3G7B
1
GYRB_STAAU
B:
[1-184]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
48.62
51%
-69
- C3 -
4URN
1
?
C:
[19-224]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
D
K
-
R
G
L
H
H
L
V
Y
E
I
V
D
N
S
V
D
E
V
L
N
G
Y
G
N
E
I
D
V
T
I
N
K
D
G
S
I
S
I
E
D
N
G
R
G
M
P
T
G
I
H
K
-
S
G
K
P
T
V
E
V
I
F
T
V
L
--------------------
G
A
S
V
V
N
A
L
S
E
W
L
E
V
E
I
H
R
D
G
N
I
Y
H
Q
S
F
K
N
G
G
S
P
S
S
G
L
V
---
K
K
G
--
K
--
T
--
K
--
K
--
T
G
T
K
V
T
F
K
P
D
D
T
I
F
K
A
S
T
-
S
-
F
N
F
D
V
L
S
E
R
L
Q
E
S
A
F
L
L
K
N
L
K
I
T
L
N
D
L
R
---
S
G
--------
K
E
R
Q
E
H
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
48.53
47%
-56
- C3 -
3TTZ
3
GYRB_STAAU
A:
[2-195]
------
Y
G
A
G
Q
I
Q
V
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
140
Fugue
48.45
72%
-46
- C3 -
1EI1
1
GYRB_ECOLI
A:
[220-391]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
K
A
F
V
-
E
Y
L
N
K
N
K
T
P
I
H
-
P
N
I
-
F
Y
F
S
T
E
K
D
G
I
G
V
E
V
A
L
Q
W
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
48.30
47%
-61
- C3 -
3TTZ
3
GYRB_STAAU
B:
[8-195]
------------
Q
V
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
---
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
PsiBlast_CBE
48.16
47%
-60
- C3 -
3U2D
4
GYRB_STAAU
B:
[8-195]
------------
Q
V
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
--
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
PsiBlast_CBE
48.02
47%
-55
- C3 -
3U2D
3
GYRB_STAAU
A:
[2-195]
------
Y
G
A
G
Q
I
Q
V
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
47.98
47%
-60
- C3 -
3U2K
3
GYRB_STAAU
B:
[8-195]
------------
Q
V
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
---
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
47.48
51%
-66
- C3 -
4URN
2
?
B:
[32-223]
-----------------------------
G
S
T
D
K
-
R
G
L
H
H
L
V
Y
E
I
V
D
N
S
V
D
E
V
L
N
G
Y
G
N
E
I
D
V
T
I
N
K
D
G
S
I
S
I
E
D
N
G
R
G
M
P
T
G
I
H
K
-
S
G
K
P
T
V
E
V
I
F
T
V
L
------------------
G
V
G
A
S
V
V
N
A
L
S
E
W
L
E
V
E
I
H
R
D
G
N
I
Y
H
Q
S
F
K
N
G
G
S
P
S
S
G
L
V
---
K
K
G
--
K
--
T
--
K
--
K
--
T
G
T
K
V
T
F
K
P
D
D
T
I
F
K
A
S
T
-
S
-
F
N
F
D
V
L
S
E
R
L
Q
E
S
A
F
L
L
K
N
L
K
I
T
L
N
D
L
R
---
S
G
--------
K
E
R
Q
E
H
--
Y
H
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
47.43
47%
-54
- C3 -
3U2K
4
GYRB_STAAU
A:
[2-195]
------
Y
G
A
G
Q
I
Q
V
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107
PsiBlast_CBE
47.21
48%
-56
- C3 -
3G7B
1
GYRB_STAAU
A:
[1-184]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108
PsiBlast_CBE
47.06
48%
-67
- C3 -
3G75
1
GYRB_STAAU
B:
[1-184]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
109
PsiBlast_CBE
46.90
48%
-62
- C3 -
3G75
1
GYRB_STAAU
A:
[1-184]
----------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
S
E
-
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
I
Q
E
K
M
G
R
P
A
V
E
V
I
L
T
-----------------------
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
-
G
V
P
Q
F
D
L
K
---
E
V
G
--
T
--
T
--
D
--
K
--
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
-
T
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
E
R
DEE
N
V
--------
R
E
--
D
S
--
Y
H
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
44.43
35%
-62
- C3 -
4KQV
2
?
B:
[8-217]
----------
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
T
N
I
E
N
P
----
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
I
H
P
E
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
--------------
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
-
G
F
K
T
K
D
L
E
II
D
N
V
G
--
K
--
K
--
N
-----
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
D
I
-
K
-
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
E
I
---
K
K
--------
E
K
--
L
T
--
W
H
F
E
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
PsiBlast_CBE
43.44
44%
-60
- C3 -
4B6C
3
GYRB_MYCSM
B:
[30-196]
-------------------------------
T
G
E
-
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
F
A
T
R
V
D
V
K
I
H
A
D
G
S
V
E
V
R
D
D
G
R
G
I
P
V
E
M
H
A
-
T
G
M
P
T
I
D
V
V
M
T
--------------------
Q
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
T
V
L
R
D
G
Y
E
W
F
Q
Y
Y
D
R
-
S
V
P
G
-
K
L
K
---
Q
G
G
--
E
--
T
--
K
--
E
--
T
G
T
T
I
R
F
W
A
D
P
E
I
F
-
E
T
T
-
D
-
Y
N
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
E
L
T
D
E
R
---
D
G
--------
K
H
--
R
V
--
F
H
Y
P
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------