@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0029: (2015-12-18 )
MWTRLLPFLAWLPGLHRGMLGREAWVGLNGAILALPQSMAYALIAGLPAEYGLYAAMLPVAIACLWGSSRYLVSGPTAAISVLLFSSVAPLAPLGSPQYVQAVLLLTFLAGAFQWLLGVLRVGSLVNFVSHSVMLGFTLGAALLIVLGQLPYLLGLAASGEGAAPGNGWRLLARFAEFDGPSLLVGGFSFALSLLVRRLRPRWPALLLGLLGGATLVWALPGTFASVAHVQALSSALPGWSPLVFDSRSILDLLPAAVACGMLGLVTSLSIARALAARQGDAFDANQEVRAQGLSNLLGPWLSASLSAGSFTRSGLNLEAGARSPLAGAFSALWVALLAVLGARLIEHVPLPAMAAGILLIAWGLIDRPALRALYRSGRAECLVAGLTALATLLLPLQNAIYAGVLASLVFYLRRTSTPRVLRQRNDEEEVLRIEGSIFFGACDYLQRLMRQCDRPRLVLDARQVNFIDFAGAVLLQQEARRLHAEGRRLVLRHARPQVREALGRQADEGCRLHYEG
Atome Classification :
(20 SA)
.........10........20........------30........40........50........60.....-...70........80........90-----------......-..100.......110.......120--.........130.......140...---.-...150.......160.......170.......180.......190....-----...200---....---...210......---.220--.......230..-.....240---........250.....---..260--.........270....-...280--.........290.........300....---...310.......320....----...330.......340-.--.......350------.........-------360.......370.......380.......390.-----------..-....400.......410.......420....--...430----.....---...440..-......450--.-.-----------------------------------------.---..-..460.......470......------------.480...-....490.-....--..500.......510--.---.....--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MW
T
R
L
L
P
F
L
A
W
L
P
G
L
H
R
G
MLGR
E
A
W
VGLN------
G
A
I
L
A
L
P
Q
S
M
A
Y
A
L
I
AGL
P
A
E
Y
G
L
Y
A
A
M
L
P
V
A
I
A
C
LW-GSS
R
Y
L
VSG
P
T
A
A
I
S
V
L
L
F
SSVAPL-----------APLG
S
P
-
Q
Y
V
Q
A
V
L
L
L
T
F
L
A
G
A
F
Q
W
L
L
G
V
L
----
R
V
G
S
L
V
N
F
V
S
H
S
V
M
L
G
F
T
L
G
A
A
L
L
I
---
V
-
L
GQ
L
P
Y
L
L
G
LAASGEGAAPG
N
G
W
R
L
L
A
R
F
A
EFDGP
S
L
L
V
G
G
F
S
F
A
L
S
L
L
V
-----
R
RLRPR---
W
P
A
L
---
L
L
G
L
LGG
A
T
L
V
W
---ALP
G
--
T
F
A
S
V
A
H
V
Q
A
L
S
-
S
ALPGWS----
P
L
V
FD
S
R
S
I
L
D
L
L
P
A
A
---
V
A
C
----
G
M
L
G
L
V
T
S
L
S
I
A
R
A
L
A
-ARQG----DAFDA
N
Q
E
V
R
--
A
Q
G
L
S
N
L
L
G
P
W
L
S
ASL---SAGSFTRSGLNLEAGARSP
L
----
A
G
A
F
S
A
L
W
V
A
L
L
A
V
L
--
G
--
A
R
L
I
EHVP--------
L
P
A
M
A
A
G
I
L
-------
L
I
A
W
G
LID
R
P
A
L
R
A
L
Y
R
SG
R
A
E
C
L
V
A
G
L
T
A
L
A
T
L
-----------
L
L
-
P
L
Q
N
A
I
Y
A
G
V
L
A
S
L
V
F
Y
L
RRTS
T
P
R
V
L
R
QRN--
D
E
E
E
V
-----
L
R
IEG---
S
I
F
F
-
G
A
C
-
D
Y
L
Q
R
L
M
R
Q--C-D-----------------------------------------R---P
R
-
L
V
L
DARQ
V
N
F
I
D
F
A
G
A
V
L
L
Q
Q
------------
E
A
R
R
L
H
A-EGR
R
L
V
L
R
-HA
R
P
--
Q
V
R
E
A
L
GRQADEG
C
---
R
---
L
HYEG--
22
Fugue
92.68
23%
-116
- C2 -
5DA0
2
?
A:
[14-484]
-------
Q
R
E
W
F
A
N
-----
P
R
K
D
V
L
A
G
I
V
------
V
A
L
A
L
I
P
E
A
I
A
F
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I
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G
V
D
P
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Y
A
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A
L
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-
G
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M
I
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A
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A
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A
L
L
M
T
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V
------------------
K
D
-
H
G
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Y
L
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A
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V
V
F
G
W
A
----
K
L
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M
V
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F
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N
A
L
A
I
L
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---
F
-
M
A
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L
P
Q
F
V
G
-----------
A
N
W
Q
M
Y
A
M
V
A
A
G
L
A
I
I
Y
L
-------
L
P
L
V
F
-----
K
A
M
-------
P
S
A
---
L
V
A
I
V
V
L
T
V
V
A
V
---
V
T
G
A
--
D
V
K
T
V
G
D
M
G
T
L
P
-
T
A
L
P
H
F
Q
FPQV
P
L
T
F
E
T
L
A
I
I
--
F
P
V
A
---
L
T
L
----
S
L
V
G
L
L
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S
L
L
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A
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T
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----
T
T
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D
K
N
V
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R
--
G
Q
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F
F
G
G
M
A
---
G
C
A
M
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S
M
I
N
V
T
S
G
G
R
G
R
L
----
S
T
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V
A
G
A
F
L
M
V
L
I
L
A
--
L
--
Q
P
L
L
V
Q
I
P
--------
M
A
A
L
V
A
V
M
M
-------
V
V
A
I
S
T
F
D
W
G
S
L
R
F
---
P
K
G
E
T
V
V
M
L
A
T
V
A
V
T
V
F
-----------
T
H
-
D
L
S
L
G
V
L
I
G
V
V
L
S
A
L
F
F
A
R
K
V
S
Q
L
S
Q
V
T
P
V
D
E
V
D
G
T
R
T
-----
Y
R
V
R
G
---
Q
L
F
F
V
S
T
H
-
D
F
L
H
Q
F
D
F
T
--
H
-
P
-----------------------------------------
A
---
R
R
-
V
V
I
D
L
S
D
A
H
F
W
D
G
S
A
V
G
A
L
D
K
------------
V
M
L
K
F
M
R
-
Q
G
T
S
V
E
L
R
-
G
L
N
A
--
A
S
A
T
L
V
E
R
L
-------------------
1
PsiBlast_PDB
89.23
24%
-122
- C2 -
5DA0
2
?
A:
[23-484]
---------------------
K
D
V
L
A
G
I
V
------
V
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
V
D
P
Q
V
G
L
Y
A
S
F
I
I
A
L
I
T
A
F
L
-
G
G
R
P
G
M
I
S
A
A
T
G
A
M
A
L
L
M
------------------
T
G
L
V
K
D
-
H
G
I
Q
Y
L
F
A
A
T
V
L
T
G
V
L
Q
V
V
F
G
W
A
----
K
L
A
R
Y
L
K
F
V
P
R
S
V
M
V
G
F
V
N
A
L
A
I
L
I
---
F
-
M
A
Q
L
P
Q
F
V
-----------
G
A
N
W
Q
M
Y
A
M
V
A
A
-----------
G
L
A
I
I
Y
L
L
-----
P
L
V
F
K
A
---
M
P
S
A
---
L
V
A
I
V
V
L
T
V
V
A
V
---
V
T
G
A
--
D
V
K
T
V
G
D
M
G
T
L
P
-
T
A
L
P
H
F
Q
FPQV
P
L
T
F
E
T
L
A
I
--
I
F
P
V
A
---
L
T
L
----
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
-
E
R
T
D
----
T
T
S
D
K
N
V
E
S
R
--
G
Q
G
V
A
N
I
V
T
G
F
F
G
G
M
A
---
G
C
A
M
I
G
Q
S
M
I
N
V
T
S
G
G
R
G
R
L
S
T
F
V
A
G
A
F
--
L
M
V
L
I
L
A
L
------
Q
P
L
L
V
Q
I
P
--------
M
A
A
L
V
A
V
M
M
-------
V
V
A
I
S
T
F
D
W
G
S
L
R
----
F
P
K
G
E
T
V
V
M
L
A
T
V
A
V
T
V
-----------
F
T
H
D
L
S
L
G
V
L
I
G
V
V
L
S
A
L
F
F
A
R
K
V
S
Q
---
L
S
Q
V
T
--
P
V
D
E
V
DG
T
R
T
Y
R
V
R
G
---
Q
L
F
F
-
V
S
T
H
D
F
L
H
Q
F
D
F
T
--
H
-
P
-----------------------------------------
A
---
R
R
-
V
V
I
D
L
S
D
A
H
F
W
D
G
S
A
V
G
A
L
D
K
V
M
L
K
F
M
R
Q
G
T
S
V
E
L
R
G
L
N
A
-
A
S
A
T
L
V
E
R
L----------------------------------
24
Fugue
69.03
21%
-114
* C1 *
3IF5
-
?
A:
[1-448]
M
R
H
------------------------------------
P
I
P
D
Y
L
A
S
L
V
T
E
L
G
A
V
N
P
G
E
T
A
Q
Y
I
P
V
L
A
------------
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
-----------
H
C
A
G
D
A
-
D
-------------------------------
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
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---
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
---
A
F
N
E
L
S
L
E
A
E
S
H
R
P
D
N
A
-
M
I
N
A
G
A
L
A
V
H
Q
L
L
V
GPEAS
R
K
E
R
L
D
---
R
A
V
E
---
I
M
S
L
L
A
G
R
R
L
S
V
D
W
E
T
Y
E
S
--
E
M
A
V
S
D
R
N
L
S
L
A
-
H
M
L
R
S
Y
G
----
V
L
Q
D
S
A
E
E
I
V
A
G
Y
V
A
Q
---
C
A
V
-----
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
-
T
G
G
I
----
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P
M
T
G
E
R
M
L
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--
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I
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A
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R
V
V
S
V
M
T
S
S
G
M
YDA
A
G
Q
W
L
A
D
V
G
I
P
----
A
K
S
G
V
----
A
G
-------
G
V
L
G
A
L
--
P
--
G
R
-------------------
V
G
I
G
-------
V
F
S
------
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
-----------
H
L
-
M
D
G
D
--------------
S
L
G
G
T
A
V
R
F
V
E
R
E
--
G
D
R
V
F
-----
L
H
L
Q
G
---
V
I
R
F
-
G
G
A
-
E
A
V
L
D
A
L
T
D
LR
T
-
G
-----------------------------------------
I
---
R
T
-
V
V
L
N
L
A
R
V
D
R
I
D
D
V
G
R
R
L
I
A
E
------------
G
V
R
R
L
Q
A
-
D
G
V
R
V
E
V
E
-
D
P
E
R
--
I
L
--------------------------
29
Fugue
65.91
20%
-126
- C1 -
4ZOX
-
SQT1_YEAST
A:
[3-381]
M
S
N
N
S
L
T
Y
F
D
----------------
K
H
T
------
D
S
V
F
A
I
G
H
H
P
N
L
P
L
V
C
T
G
G
G
D
N
----------
L
A
H
L
W
-
T
S
H
----
S
Q
P
P
K
F
A
G
T
L
------------------------
T
-
G
Y
G
E
S
V
I
S
C
S
F
T
S
-----------------------
E
G
G
F
L
V
T
A
D
M
S
G
K
V
L
V
---
H
-
M
G
Q
K
G
--------------
G
A
Q
W
K
L
A
S
Q
M
Q
E
V
E
E
I
V
W
L
K
T
H
P
T
I
A
--------------------
R
T
F
---
A
F
G
A
T
D
G
S
--
V
W
---
C
Y
Q
I
--
N
E
Q
D
G
S
L
E
Q
L
M
S
-
G
F
V
H
Q
----------
Q
D
C
S
M
G
E
F
I
N
T
D
---
K
G
E
----
N
T
L
E
L
V
T
C
S
L
D
S
T
I
V
A
-
W
N
-------
C
F
T
G
Q
Q
L
F
K
I
T
Q
A
E
I
K
G
L
E
A
P
W
I
S
L
S
L
---
A
P
E
T
L
T
K
-------
G
N
S
G
V
V
----
A
C
G
S
N
N
G
L
L
A
V
I
N
C
N
--
N
--
G
G
A
I
L
H
L
S
T
V
I
E
L
K
PE
Q
D
E
L
D
A
S
I
E
-------
S
I
S
W
S
-------------
S
K
F
S
L
M
A
I
G
L
V
C
G
E
I
L
-----------
L
Y
-
D
T
S
A
W
--------------
R
V
R
H
K
F
V
L
E
-----
D
S
V
T
K
-----
L
M
F
D
N
---
D
D
L
F
-
A
S
C
-
I
N
G
K
V
Y
Q
F
N
--
A
-
R
TG---------------------------------------
Q
---
E
K
-
F
V
C
V
G
H
N
M
G
V
L
D
F
---
I
L
L
H
P
------------
V
A
N
T
G
T
E
-
Q
K
R
K
V
I
T
A
-
G
---------------
D
E
G
V
---
S
---
L
V
F
E
V
P
N
4
PsiBlast_PDB
63.72
25%
-88
- C2 -
3QE7
2
URAA_ECOLI
A:
[45-356]
---------------------------------------------------------------------------------------
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
KGK
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
L
L
P
L
-
G
Y
E
V
A
L
G
G
F
I
----
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
-
M
G
A
I
V
A
V
I
G
L
E
L
A
G
--
V
A
A
G
M
A
G
L
L
P
A
E
G
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
-----
S
V
L
F
R
G
---
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
---
A
M
-
G
--
I
V
D
T
T
P
I
I
N
A
H
W
-
F
A
L
P
T
L
Y
----
T
P
R
F
E
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
----
H
V
G
H
L
V
V
T
A
N
I
V
K
K
D
L
-
L
R
D
P
-------
G
L
H
R
S
M
F
--
A
N
G
L
S
T
V
I
S
G
F
F
G
S
T
P
---
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
R
V
Y
S
T
W
----
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
--
G
K
L
A
A
A
I
Q
M
I
P
--------
L
P
V
M
-
G
G
V
S
-------
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
-----------
L
I
-
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
--
F
K
L
I
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
62.54
15%
-113
- C2 -
3QE7
2
URAA_ECOLI
A:
[11-410]
----------------
R
P
P
L
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
A
T
V
L
V
P
V
L
F
H
------
I
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
L
L
P
--------------------
L
G
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
E
L
---
A
-
G
V
A
A
G
M
A
G
L
L
P
A
-
E
G
--------------
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
-----
S
V
L
F
R
G
FLA
I
I
P
I
---
L
I
G
V
L
V
G
Y
A
L
S
F
---
A
M
G
I
--
V
D
--
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
Y
T
---
P
R
F
-
E
W
----
F
A
I
L
T
I
---
L
P
A
----
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
-
N
I
V
K
KDLL
R
D
P
G
L
H
R
S
M
F
--
A
N
G
L
S
T
V
I
S
G
F
F
G
S
T
P
---
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
R
V
Y
S
T
W
----
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
K
L
--
A
A
A
I
Q
M
I
P
--------
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
-
N
--
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
GAKVNIGAAE
L
K
-
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
53.91
12%
-112
- C2 -
1TO6
4
GLXK_NEIMA
A:
[1-371]
-----
M
K
I
V
I
A
P
D
S
F
K
E
S
L
T
A
Q
Q
V
A
E
A
I
K
------
R
G
F
Q
Q
S
I
A
D
---
V
E
C
L
L
C
P
V
G
D
G
G
E
G
T
V
D
A
I
R
H
S
L
D
L
-
E
E
K
C
L
Q
V
T
G
S
F
G
Q
K
E
V
M
R
Y
F
Q
K
E
Q
----------------------
L
A
L
F
E
V
A
D
L
V
G
-----
L
G
K
I
----
P
L
E
K
R
N
P
L
Q
I
Q
T
R
G
I
G
E
L
I
R
H
L
I
S
Q
---
E
-
I
K
E
I
Y
I
G
V
G
------
G
T
A
S
N
D
G
-------------------------------------------------------
G
I
G
I
A
A
---
G
L
G
Y
--
Q
F
Y
D
E
D
G
N
A
L
P
A
-
C
G
Q
S
L
L
N
----
L
A
S
V
S
T
E
N
R
Y
K
I
P
E
D
V
---
H
I
R
----
I
L
A
D
V
V
S
P
L
C
G
H
Q
G
A
T
-
Y
T
F
G
----
K
Q
K
G
L
D
-
S
T
M
--
F
E
V
V
D
Q
A
I
Q
D
F
Y
E
K
V
S
---------------
P
A
T
L
K
L
K
G
----
A
G
A
G
G
G
I
A
G
G
L
C
A
F
A
--
Q
--
A
S
I
V
S
---------------
G
I
D
T
C
-------
L
D
L
I
D
F
D
K
K
V
S
--------
D
V
D
L
V
I
V
G
E
G
R
L
D
R
Q
--------------
S
L
A
G
K
A
P
I
G
V
A
----------------
K
R
T
P
--
V
G
V
P
V
-----
V
A
I
C
G
---
S
L
----------------------------------------------------------------------
V
E
D
L
P
S
L
P
F
E
N
I
Q
A
A
F
S
I
L
E
------------
K
S
E
P
----------
L
E
-
D
S
L
K
--
N
A
S
L
Y
L
E
H
T
A
S
N
I
G
---
H
---
L
L
N
M
P
KI
19
HHSearch
52.55
27%
-57
- C2 -
3AGD
-
?
A:
[325-447]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
V
F
-----
L
H
L
Q
G
---
V
I
R
F
-
G
G
A
-
E
A
V
L
D
A
L
T
D
--
L
-
R
TGWDAAVY
P
R
W
Q
E
A
A
A
D
R
A
A
L
S
A
A
T
GGGA
V
H
E
A
A
A
A
A
ANDG
P
---
I
R
T
V
V
L
N
L
A
R
V
D
R
I
D
D
V
G
R
R
L
I
A
E
------------
G
V
R
R
L
Q
A
-
D
G
V
R
V
E
V
E
-
D
P
E
R
--
I
L
P
L
------------------------
3
PsiBlast_PDB
51.39
26%
-59
- C2 -
4DGH
5
?
A:
[14-97]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
T
L
P
R
---------
E
L
A
V
-----
Y
A
L
E
G
---
P
F
F
F
-
A
A
A
-
E
T
F
E
R
V
M
G
S
--
I
Q
E
-----------------------------------------
T
---
P
Q
I
L
I
L
R
L
K
W
V
P
F
M
D
I
T
G
I
Q
T
L
E
E
------------
M
I
Q
S
F
H
K
-
R
G
I
K
V
L
I
S
-
G
A
N
S
--
R
V
S
Q
K
L
V
K
A
G
I
V
K
L
---
V
---
G
E
Q
N
V
--
2
PsiBlast_PDB
50.39
26%
-54
- C2 -
3MGL
4
?
A:
[14-97]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
T
L
P
R
---------
E
L
A
V
-----
Y
A
L
E
G
---
P
F
F
F
-
A
A
A
-
E
T
F
E
R
V
M
G
S
--
I
Q
E
-----------------------------------------
T
---
P
Q
I
L
I
L
R
L
K
W
V
P
F
M
D
I
T
G
I
Q
T
L
E
E
------------
M
I
Q
S
F
H
K
-
R
G
I
K
V
L
I
S
-
G
A
N
S
--
R
V
S
Q
K
L
V
K
A
G
I
V
K
L
---
V
---
G
E
Q
N
V
--
28
Fugue
49.38
18%
-90
- C2 -
4QCC
-
DGOA_ECOLI
A:
[5-274]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
P
L
I
A
---
I
L
R
G
IT
P
D
E
A
L
A
H
V
G
A
V
I
-
D
A
G
F
D
A
V
----
E
I
P
L
N
S
P
Q
W
E
Q
S
I
P
A
I
---
V
D
A
YGDK
A
L
I
G
A
G
T
V
L
K
P
E
Q
V
D
A
L
A
R
M
G
----
C
Q
L
I
V
T
P
N
I
H
--
S
E
V
I
R
R
A
V
G
Y
G
M
T
V
C
P
---
G
C
A
T
A
T
E
A
F
T
A
L
E
A
G
A
Q
------------
A
L
K
I
F
P
S
S
A
F
--
G
--
P
Q
Y
I
K
A
L
K
---------
A
V
L
P
S
D
I
A
-------
V
F
A
V
G
G
V
T
P
E
N
L
A
Q
W
I
D
A
G
---
C
A
G
A
G
L
G
S
--
D
L
-----------
Y
R
-
A
G
Q
S
V
E
R
T
A
Q
Q
A
A
A
F
V
K
A
Y
R
E
A
Q
K
Q
K
E
Q
R
Q
D
--
Q
K
S
A
Y
-----
A
L
G
A
S
---
L
G
R
Y
-
M
E
N
-
S
L
K
E
Q
E
K
L
G
--
I
-
K
-----------------------------------------
L
---
D
K
-
D
Q
L
I
A
G
V
Q
D
A
F
A
D
K
S
K
L
S
D
Q
E
------------
I
E
Q
T
L
Q
A
-
F
E
A
----------------------------------------
13
HHSearch
48.61
15%
-59
- C2 -
1TH8
1
SP2AA_GEOSE
B:
[9-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
--
Q
D
V
L
I
-----
V
R
L
S
G
---
E
L
D
H
-
H
T
A
-
E
E
L
R
E
Q
V
T
D
--
V
-
L
E
N
R
--------------------------------------
A
---
I
R
H
I
V
L
N
L
G
Q
L
T
F
M
D
S
S
G
L
G
V
I
L
G
------------
R
Y
K
Q
I
K
N
-
V
G
G
Q
M
V
V
C
-
A
V
S
P
--
A
V
K
R
L
F
D
M
S
G
L
F
K
I
---
I
---
R
V
E
A
D
--
10
HHSearch
48.32
18%
-46
- C2 -
1SBO
-
Y1442_THEMA
A:
[10-106]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
--
D
D
K
A
I
-----
V
R
V
Q
G
---
D
I
D
A
-
Y
N
S
-
S
E
L
K
E
Q
L
R
N
--
F
-
I
S
T
T--------------------------------------
S
---
K
K
K
I
V
L
D
L
S
S
V
S
Y
M
D
S
A
G
L
G
T
L
V
V
------------
I
L
K
D
A
K
I
-
N
G
K
E
F
I
L
S
-
S
L
K
E
--
S
I
S
R
I
L
K
L
T
H
L
D
K
I
---
F
---
K
I
T
D
T
--
12
HHSearch
47.87
24%
-61
- C2 -
3NY7
1
?
A:
[14-110]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
--
D
D
V
L
V
-----
L
R
V
I
G
---
P
L
F
F
-
A
A
A
-
E
G
L
F
T
D
L
E
S
--
R
-
L
E----------------------------------------
G
---
K
R
I
V
I
L
K
W
D
A
V
P
V
L
D
A
G
G
L
D
A
F
Q
R
------------
F
V
K
R
L
P
--
E
G
C
E
L
R
V
C
-
N
V
E
F
--
Q
P
L
R
T
M
A
R
A
G
I
Q
P
I
PGR
L
---
A
F
F
P
N
--
18
HHSearch
46.51
15%
-51
- C2 -
3T6O
1
?
A:
[10-111]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
H
E
--
A
Q
V
T
V
-----
I
S
F
P
A
VFQ
R
L
R
E
-
T
E
V
-
E
Q
I
A
S
T
F
L
A
--
A
-
M
QGA--------------------------------------
Q
---
P
R
K
V
L
I
D
L
E
G
V
E
F
F
G
S
S
F
I
E
L
L
V
R
------------
G
W
K
R
I
K
E
D
Q
Q
G
V
F
A
L
C
-
S
V
S
P
--
Y
C
V
E
V
L
Q
V
T
H
I
D
E
V
---
W
---
P
R
Y
S
T
--
15
HHSearch
46.48
12%
-30
- C2 -
2KA5
-
Y1081_THEMA
A:
[18-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
--
D
D
V
V
I
-----
L
M
P
N
K
---
E
L
N
I
-
E
N
A
-
H
L
F
K
K
W
V
F
D
--
E
F
L
NK---------------------------------------
G
---
Y
N
K
I
F
L
V
L
S
D
V
E
S
I
D
S
F
S
L
G
V
I
V
N
------------
I
L
K
S
I
S
S
-
S
G
G
F
F
A
L
V
-
S
P
N
E
--
K
V
E
R
V
L
S
L
T
N
L
D
R
I
---
V
---
K
I
Y
D
T
--
14
HHSearch
46.45
18%
-42
- C2 -
1H4X
1
SP2AA_LYSSH
A:
[9-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
--
R
E
T
V
V
-----
I
R
L
F
G
---
E
L
D
H
-
H
A
V
-
E
Q
I
R
A
K
I
S
T
--
A
-
I
-----------------------------------------
F
Q
GA
V
T
T
I
I
W
N
F
E
R
L
S
F
M
D
S
S
G
V
G
L
V
L
G
------------
R
M
R
E
L
E
A
-
V
A
G
R
T
I
L
L
-
N
P
S
P
--
T
M
R
K
V
F
Q
F
S
G
L
G
P
W
---
M
----
M
D
A
T
--
11
HHSearch
37.79
15%
-17
- C2 -
3OIZ
-
?
A:
[399-478]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
--
G
R
E
R
I
-----
Y
R
V
E
G
---
Q
L
F
Y
-
A
S
V
-
E
D
F
M
A
A
F
D
F
--
R
-
E
-----------------------------------------
A
---
L
D
R
V
V
I
D
V
S
R
A
H
I
W
D
I
S
S
V
Q
A
L
D
M
------------
A
V
L
K
F
R
R
-
E
G
A
E
V
R
I
V
-
G
M
N
E
--
A
S
E
T
M
V
----------------------
16
HHSearch
35.67
17%
5
- C2 -
2KLN
-
?
A:
[12-113]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
--
P
G
L
V
V
-----
Y
R
Y
D
A
---
P
L
C
F
-
A
N
A
-
E
D
F
R
R
R
A
L
T
--
V
-
V
DQDPG------------------------------------
Q
---
V
E
W
F
V
L
N
A
E
S
N
V
E
V
D
L
T
A
L
D
A
L
D
Q
------------
L
R
T
E
L
L
R
-
R
G
I
V
F
A
M
A
-
R
V
K
Q
--
D
L
R
E
S
L
R
A
A
S
L
L
D
K
---
I
GED
H
I
F
M
T
--
21
HHSearch
31.37
12%
66
- C2 -
2PR7
3
?
A:
[5-58]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
V
D
Y
A
G
V
L
D
G
T
D
E
D
Q
R
R
W
R
N
------------
L
L
A
A
A
K
K
-
N
G
V
G
T
V
I
L
-
S
N
D
P
GG
L
G
A
A
P
I
R
E
L
E
T
N
G
V
---
V
---
D
K
V
L
L
--