@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0032: (2015-12-19 )
MGERLMPLSLDLLRVFESAARQLSFTAAAEELGTTQPAVSQQIKRLEKELATPLFQRVHRGIVLTDAGQLLLRHVAAGLETIDAGIAALGARQRHEVLQVATDYAFAAYWLMPRLPRFHQAHPHLDVSLVTSERGLAGQRGDIDVAILFGDGRSKHGEAHRLFREEVFPVCSPRLVEGLQLPLAKAHLARLPMLHLKPAQHARWFDWPALFEALAIDRQPIPAVLSFDNYTLLIQAAIAGQGVAIGWRHLVDGLLEQGLLCRPIGESCLSRYGYYAVLPERKRRQRLVDGFVDWLQAELQAGGA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........---.90---.--....----...100.-.-.....110.......120.......130--....---....---140.....---..150.---......160-....-...170......-.-180.......190-.......200....-...210.....-..-.220.--.-..----...230-...-....-240...-....250........260-.-.......-.-270........280.....-..290.......300..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGERLMP
L
S
L
D
L
L
R
V
F
E
S
A
A
R
Q
L
S
F
T
A
A
A
E
ELGTTQ
P
A
V
S
Q
Q
I
K
R
L
E
K
E
L
A
T
P
L
F
Q
R
V
HR
G
I
V
LT
D
A
G
Q
L
L
L
R
H
V
A
A
G
L
E
-
T
I
D
A
G
I
A
A
---L
G
A
---
R
--
Q
R
H
E
----
V
L
Q
V
A
T
D
-
Y
-
A
F
A
A
Y
W
L
MPRL
P
R
F
H
QAHPH
L
D
V
S
L
V
T---SERG---LAGQ---RG
D
I
D
V
A
I
---
L
F
GDGR---SKH
G
E
A
H
R
L
-
F
R
E
E-VFPVC
S
P
R
L
V
E
G
-L-QL
P
L
A
K
A
H
L
A
RL
P
-
M
L
HLKPAQHARWF
D
-
W
P
A
L
-
F
E
A
L
AI-DR-QPI
P
A
--
V
-LS----FD
N
Y
T
L
-
L
I
Q
-
A
AIA-GQG
V
A
I
-
G
W
R
H
L
-
V
D
G
L
L
EQGLL---C-R
P
I
G
E
S
C
-
L
-
S
R-YG
Y
Y
AVL
P
E
R
K
R
R
Q
R
L
-
V
D
G
F
V
D
W
L
Q
A
E
L
QAGGA
1
PsiBlast_PDB
86.42
25%
-119
- C3 -
3HHG
-
?
A:
[2-293]
------
K
T
N
S
E
E
L
T
V
F
V
Q
V
V
E
S
G
S
F
S
R
A
A
E
Q
L
A
M
A
N
S
A
V
S
R
I
V
K
R
L
E
E
K
L
G
V
N
L
L
N
R
T
T
R
Q
L
S
L
T
E
E
G
A
Q
Y
F
R
R
A
Q
R
I
L
Q
-
E
M
A
A
A
E
T
E
---
M
L
A
-------
V
H
E
I
P
Q
G
V
L
S
V
D
S
A
-
M
-
P
M
V
L
H
L
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
---
S
E
G
Y
---
I
N
L
I
---
E
R
K
V
D
I
A
L
---
R
A
G
E
L
D
---
D
S
G
L
R
A
R
H
L
-
F
D
S
R
-
F
R
V
I
A
S
P
E
Y
L
A
K
-
H
-
G
T
P
Q
S
T
E
E
L
A
----------
G
H
Q
C
L
G
F
T
-
E
P
G
S
-
L
N
T
W
A
V
L
D
A
-
Q
G
N
P
Y
--
K
-
I
S
PHFT
A
S
S
G
E
I
-
L
R
S
-
L
C
L
S
-
G
C
G
I
V
C
-
L
S
D
F
L
-
V
D
N
D
I
A
E
G
K
L
---
I
-
P
L
L
A
E
Q
T
-
S
-
D
K
T
H
P
F
N
A
V
Y
Y
S
D
K
A
V
N
L
R
-
L
R
V
F
L
D
F
L
V
E
E
L
G
----
33
HHSearch
85.45
25%
-113
- C3 -
3HHG
-
?
A:
[2-294]
------
K
T
N
S
E
E
L
T
V
F
V
Q
V
V
E
S
G
S
F
S
R
A
A
E
Q
L
A
M
A
N
S
A
V
S
R
I
V
K
R
L
E
E
K
L
G
V
N
L
L
N
R
T
T
R
Q
L
S
L
T
E
E
G
A
Q
Y
F
R
R
A
Q
R
I
L
Q
-
E
M
A
A
A
E
T
E
---
M
L
A
V
H-
E
--
I
P
Q
G
----
V
L
S
V
D
S
A
-
M
-
P
M
V
L
H
L
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
---
S
E
G
Y
---
I
N
L
I
---
E
R
K
V
D
I
A
L
---
R
A
G
E
L
D
---
D
S
G
L
R
A
R
H
L
-
F
D
S
R
-
F
R
V
I
A
S
P
E
Y
L
A
K
-
H
-
G
T
P
Q
S
T
E
E
L
A
G
H
Q
-
C
L
G
F
T
E
P
--
G
S
L
N
T
-
W
A
-
V
-
L
D
A
Q
G
N
-
P
Y
--
K
I
S
P
--
H
-
F
T
----
A
S
S
G
E
I
-
L
R
S
-
L
C
L
S
-
G
C
G
I
V
C
-
L
S
D
F
L
-
V
D
N
D
I
A
E
G
K
L
---
I
-
P
L
L
A
E
Q
T
S
D
-
K
T
-
H
P
F
N
A
V
Y
Y
S
D
K
A
V
N
L
R
-
L
R
V
F
L
D
F
L
V
E
E
L
G
----
31
HHSearch
78.38
17%
-122
- C3 -
3SZP
-
?
A:
[1-289]
-------
M
K
L
D
D
L
N
L
F
R
L
V
V
E
N
G
S
Y
T
S
T
S
K
K
T
M
I
P
V
A
T
I
T
R
R
I
Q
A
L
E
D
S
L
N
L
R
L
L
N
R
H
A
R
K
L
T
L
T
E
A
G
E
R
F
Y
K
D
C
S
P
L
L
E
-
R
L
A
S
M
T
E
E
---
I
T
D
EC-
R
--
G
A
S
G
----
R
I
R
I
S
A
P
-
S
-
N
L
T
K
R
M
M
M
P
M
F
N
A
F
M
E
K
Y
P
D
I
H
I
E
L
M
M
---
S
N
Q
A
---
D
D
L
D
---
P
T
E
W
D
V
I
F
---
R
V
G
P
Q
R
---
D
S
S
L
I
A
R
K
I
-
G
E
V
K
-
D
I
L
V
A
S
P
Q
Y
L
S
S
-
H
-
P
Q
P
T
H
A
E
E
L
H
Q
H
Q
-
L
L
K
G
Y
P
L
-----
L
K
-
W
Q
L
--
T
N
S
Q
G
E
-
T
V
V
N
S
D
R
G
--
R
-
F
Q
----
A
S
A
L
N
V
-
V
R
S
-
A
C
S
E
-
G
L
G
I
T
L
-
M
P
D
V
M
-
L
R
E
F
L
E
D
G
S
L
---
V
-
Q
V
L
S
D
W
S
-
S
-
N
P
-
R
D
I
Y
M
L
Y
N
H
K
D
H
Q
P
E
K
-
V
R
L
F
I
D
F
V
I
G
Y
H
L
----
27
HHSearch
75.52
20%
-111
- C3 -
3FXQ
7
TSAR_COMTE
A:
[1-296]
------
M
L
K
L
Q
T
L
Q
A
L
I
C
I
E
E
V
G
S
L
R
A
A
A
Q
L
L
H
L
S
Q
P
A
L
S
A
A
I
Q
Q
L
E
D
E
L
K
A
P
L
L
V
R
T
K
R
G
V
S
L
T
S
F
G
Q
A
F
M
K
H
A
R
L
I
V
T
-
E
S
R
R
A
Q
E
E
---
I
G
Q
L
R
-
G
--
R
W
E
G
----
H
I
T
F
A
A
S
-
P
-
A
I
A
L
A
A
L
P
L
A
L
A
S
F
A
R
E
F
P
D
V
T
V
N
V
R
D
---
G
M
Y
P
AV
S
P
Q
L
R
---
D
G
T
L
D
F
A
L
---
T
A
A
H
K
H
DI-
D
T
D
L
E
A
Q
P
L
-
Y
V
S
D
-
V
V
I
V
G
Q
R
Q
H
P
M
A
-
N
-
A
--
T
R
L
A
E
L
Q
E
C
R
-
W
A
F
S
S
A
P
-
R
G
P
G
A
I
-
I
R
N
A
-
F
A
R
Y
G
L
-
P
---
E
P
K
L
--
G
-
L
V
----
C
E
S
F
L
A
-
L
P
G
-
V
V
A
H
-
S
D
L
L
T
T
-
M
P
R
T
L
-
Y
E
R
N
A
F
K
D
Q
L
---
C
-
S
I
P
L
Q
D
A
-
L
-
P
N
-
P
T
I
Y
V
L
R
R
H
D
L
P
V
T
P
A
-
A
A
G
L
I
R
W
I
Q
H
H
A
L
----
28
HHSearch
74.00
19%
-118
- C3 -
2ESN
-
?
A:
[3-303]
--
P
L
L
R
R
L
D
L
N
L
L
L
V
F
D
A
L
Y
R
H
R
N
V
G
T
A
A
S
E
L
A
I
S
A
S
A
F
S
H
A
L
G
R
L
R
Q
G
L
D
D
E
L
F
L
R
Q
G
N
R
M
Q
P
T
Q
R
A
E
H
L
A
A
A
V
A
A
A
L
R
-
A
L
G
E
G
L
E
E
---
W
R
P
FVP
G
--
Q
S
Q
R
----
T
F
V
F
A
A
T
-
D
-
Y
T
A
F
A
L
L
P
P
L
M
N
R
L
Q
H
S
A
P
G
V
R
L
R
L
V
N
---
A
E
R
K
LS
V
E
A
L
A
---
S
G
R
I
D
F
A
L
---
G
Y
D
E
E
H
ERL
P
E
G
I
Q
A
H
D
W
-
F
A
D
R
-
Y
V
V
V
A
R
R
D
H
P
R
L
-
A
-
G
-
A
P
T
L
E
G
Y
L
A
E
R
-
H
A
V
V
T
P
W
-
N
E
D
S
G
V
-
I
D
R
L
-
L
A
R
S
G
L
-
R
----
R
E
V
--
A
-
V
Q
----
L
P
T
V
L
A
-
A
L
F
-
L
A
G
S
-
T
D
F
L
L
T
-
A
P
R
H
A
-
A
R
A
L
A
E
A
A
G
L
---
A
-
L
Y
P
A
P
F
D
-
I
-
P
P
-
Y
V
L
R
L
Y
S
H
V
Q
--
G
R
D
A
-
H
A
W
M
I
G
Q
L
K
G
L
D
-----
52
Fugue
73.07
20%
-111
- C3 -
2ESN
-
?
A:
[3-303]
--
P
L
L
R
R
L
D
L
N
L
L
L
V
F
D
A
L
Y
R
H
R
N
V
G
T
A
A
S
E
L
A
I
S
A
S
A
F
S
H
A
L
G
R
L
R
Q
G
L
D
D
E
L
F
L
R
Q
G
N
R
M
Q
P
T
Q
R
A
E
H
L
A
A
A
V
A
A
A
L
R
-
A
L
G
E
G
L
E
E
WRP
F
V
P
---
G
--
Q
S
Q
R
----
T
F
V
F
A
A
T
-
D
-
Y
T
A
F
A
L
L
P
P
L
M
N
R
L
Q
H
S
A
P
G
V
R
L
R
L
V
N
AER
K
L
S
V
---
E
A
L
A
---
S
G
R
I
D
F
A
L
G
Y
D
E
E
H
E
R
L
---
P
E
G
I
Q
A
H
D
W
-
F
A
D
R
-
Y
V
V
V
A
R
R
D
H
-
P
R
-
L
-
A
G
A
P
T
L
E
G
Y
L
A
E
R
-
H
A
V
V
T
P
W
N
E
D
S
-----
G
V
I
-
D
R
L
L
A
R
-
S
G
-
L
R
R
E
V
--
A
-
V
Q
----
L
P
T
V
L
A
-
A
L
F
-
L
A
G
S
-
T
D
F
L
L
T
-
A
P
R
H
A
-
A
R
A
L
A
E
A
A
G
L
---
A
-
L
Y
P
A
P
F
D
-
I
-
P
P
-
Y
V
L
R
L
Y
S
H
V
Q
G
-------
R
D
A
H
A
W
M
I
G
Q
L
K
G
L
D
-
7
PsiBlast_PDB
67.81
26%
-138
- C3 -
2QSX
1
?
A:
[19-214]
--------------------------------------------------------------------------------------------------------
E
----
L
L
V
V
D
V
T
-
P
-
S
F
A
S
L
W
L
V
P
N
I
N
D
F
H
Q
R
H
P
N
I
R
V
K
I
L
T
---
G
D
G
A
---
V
--------
E
S
D
L
H
V
---
R
C
L
-
P
L
---
S
T
H
Y
E
Y
S
Q
L
-
L
C
E
E
-
T
L
L
L
I
G
N
T
N
L
P
---------
I
S
H
Y
P
F
I
P
--------
Q
T
T
R
-----
P
Q
L
-
W
E
Q
F
K
Q
-
E
N
---
I
T
Y
H-
S
-
V
G
----
F
E
H
F
Y
L
-
A
C
E
-
A
V
R
M
-
E
K
G
L
A
L
-----
L
-
P
D
F
M
A
Q
F
S
I
L
R
GD
I
-
Q
H
I
G
N
L
K
-
L
H
S
G
-
Y
G
Y
Y
V
V
I
P
N
F
R
L
T
S
R
K
-
V
A
L
F
H
D
W
L
K
D
K
L
T
----
20
PsiBlast_PDB
66.47
22%
-134
- C3 -
3HHF
1
?
B:
[8-207]
-------------------------------------------------------------------------------------------------------------
V
L
S
V
D
S
A
-
M
-
P
M
V
L
H
L
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
---
S
E
G
Y
---
I
N
L
I
---
E
R
K
V
D
I
A
L
---
R
A
G
--
D
---
D
S
G
L
R
A
R
H
L
-
F
D
S
R
-
F
R
V
I
A
S
P
E
Y
L
A
K
-
H
-
G
T
P
Q
S
T
E
E
L
A
----------
G
H
Q
C
L
G
F
T
-
E
P
G
S
-
L
N
T
W
A
V
L
D
A
-
Q
G
N
P
Y
--
K
-
I
S
PH
F
T
A
S
S
G
E
I
-
L
R
S
-
L
C
L
S
-
G
C
G
I
V
C
-
L
S
D
F
L
-
V
D
N
D
I
A
E
G
K
L
---
I
-
P
L
L
A
E
Q
T
-
S
-
D
K
T
H
P
F
N
A
V
Y
Y
S
D
K
A
V
N
L
R
-
L
R
V
F
L
D
F
L
V
E
E
L
G
----
53
Fugue
65.26
18%
-99
- C3 -
3FZV
1
?
A:
[4-300]
-------
Y
T
L
R
Q
L
K
Y
F
V
T
T
V
E
C
G
S
V
A
E
A
S
R
K
L
Y
I
A
Q
S
-
I
S
T
A
V
K
G
L
E
E
S
F
V
---------
Q
L
F
L
T
P
A
G
A
R
F
Y
R
K
A
Q
E
L
L
R
M
A
H
E
F
E
Q
N
L
---
A
D
N
---
D
--
V
I
A
G
----
Q
I
D
I
G
C
F
-
E
-
T
V
A
P
L
Y
L
P
G
L
I
A
G
F
R
Q
A
Y
P
G
V
E
I
R
I
R
D
---
G
E
Q
Q
---
E
L
V
Q
G
L
T
S
G
R
F
D
L
A
F
---
L
Y
E
H
D
L
---
D
S
T
I
E
T
E
P
L
M
P
P
Q
R
-
P
H
A
L
L
P
E
G
H
R
F
A
-
G
-
Q
A
Q
V
S
L
R
D
L
C
L
E
P
M
I
L
L
D
V
Q
-------
P
-
S
R
T
Y
-
F
V
S
L
F
E
-
E
L
-
G
L
T
P
N
--
I
-
A
F
----
S
S
P
S
I
E
M
V
R
G
M
V
G
-
Q
-
G
F
G
F
S
L
L
V
T
R
P
H
-
S
E
C
T
Y
D
G
K
K
V
---
V
M
V
D
L
A
E
P
--
V
-
S
T
-
S
G
L
A
A
A
W
L
K
R
A
Q
L
T
K
P
-
A
R
L
F
V
D
Y
C
R
E
Q
L
G
K
---
51
Fugue
64.23
18%
-108
- C3 -
1IZ1
-
?
A:
[1-292]
-------
M
E
F
R
Q
L
K
Y
F
I
A
V
A
E
A
G
N
M
A
A
A
A
K
R
L
H
V
S
Q
P
P
I
T
R
Q
M
Q
A
L
E
A
D
L
G
V
V
L
L
E
R
S
H
R
G
I
E
L
T
A
A
G
H
A
F
L
E
D
A
R
R
I
L
E
-
L
A
G
R
S
G
D
R
---
S
R
A
---
A
--
A
R
G
D
V
G
--
E
L
S
V
A
Y
F
-
G
-
T
P
I
Y
R
S
L
P
L
L
L
R
A
F
L
T
S
T
P
T
A
T
V
S
L
T
H
M
T
K
D
E
Q
V
---
E
G
L
L
---
A
G
T
I
H
V
G
F
---
S
R
F
F
P
R
---
H
P
G
I
E
I
V
N
I
-
A
Q
E
D
-
L
Y
L
A
V
H
R
S
Q
S
G
K
-
F
-
G
K
T
C
K
L
A
D
L
R
A
V
E
-
L
T
L
F
P
R
G
G
R
P
S
--
F
-
A
D
E
V
-
I
G
L
F
K
H
-
A
G
-
I
E
P
R
I
--
A
-
R
V
----
V
E
D
A
T
A
-
A
L
A
-
L
T
M
A
-
G
A
A
S
S
I
-
V
P
A
S
V
-
A
A
-
I
R
W
P
D
I
A
---
F
-
A
R
I
V
G
T
----
R
V
-
K
V
P
I
S
C
I
F
R
K
E
K
Q
P
P
I
-
L
A
R
F
V
E
H
V
R
R
S
A
-----
38
HHSearch
63.77
20%
-95
- C3 -
3ISP
-
Y1985_MYCTU
A:
[5-291]
------
Q
L
D
G
P
Q
L
A
A
L
A
A
V
V
E
L
G
S
F
D
A
A
A
E
R
L
H
V
T
P
S
A
V
S
Q
R
I
K
S
L
E
Q
Q
V
G
Q
V
L
V
V
R
E
-
K
P
C
R
A
T
T
A
G
I
P
L
L
R
L
A
A
Q
T
A
L
-
L
E
S
E
A
L
A
E
---
M
G
-A--
S
--
L
K
R
T
----
R
I
T
I
A
V
N
-
A
-
D
S
M
A
T
W
F
S
A
V
F
D
----
G
L
G
D
V
L
L
D
V
R
I
---
E
D
Q
D
H
S
A
R
L
L
R
---
E
G
V
A
M
G
A
V
---
T
T
E
R
N
P
---
V
P
G
C
R
V
H
P
L
-
G
E
M
R
-
Y
L
P
V
A
S
R
P
F
V
Q
R
-
H
L
S
D
G
F
T
A
A
A
A
A
K
A
P
-
S
L
A
W
N
R
D
-
D
G
L
Q
D
M
L
V
R
K
A
-
F
R
R
A
I
T
-------
R
P
--
T
-
H
F
----
V
P
T
T
E
G
-
F
T
A
-
A
A
R
A
-
G
L
G
W
G
M
-
F
P
E
K
L
-
A
A
S
P
L
A
D
G
S
F
---
V
-
R
V
C
D
-
I
-----
H
-
L
D
V
P
L
Y
W
Q
C
W
K
L
D
S
P
I
-
I
A
R
I
T
D
T
V
R
A
A
A
S
G
L
Y
R
49
Fugue
63.12
23%
-134
- C3 -
2QSX
1
?
A:
[19-215]
--------------------------------------------------------------------------------------------------------
E
----
L
L
V
V
D
V
T
-
P
-
S
F
A
S
L
W
L
V
P
N
I
N
D
F
H
Q
R
H
P
N
I
R
V
K
I
L
T
---
G
D
G
A
---
V
--------
E
S
D
L
H
V
---
R
C
L
P
L
S
---
T
H
Y
E
Y
S
Q
L
L
-
C
E
E
T
-
L
L
L
I
G
N
T
N
L
-------------
P
I
S
H
Y
P
-
F
I
P
Q
T
T
R
P
Q
----
L
-
W
E
Q
F
-
K
Q
E
N
I
T
-
Y
H
-
S
V
--------
G
----
F
E
H
F
Y
L
-
A
C
E
-
A
V
-
R
M
E
K
G
L
A
L
-
L
P
D
-
F
M
A
Q
F
S
I
L
R
G
D
I
---
Q
-
H
I
G
N
L
K
L
-
H
-
S
G
-
Y
G
Y
Y
V
V
I
P
N
F
R
L
T
S
R
K
-
V
A
L
F
H
D
W
L
K
D
K
L
T
----
54
Fugue
63.02
20%
-87
- C3 -
3ISP
-
Y1985_MYCTU
A:
[5-296]
------
Q
L
D
G
P
Q
L
A
A
L
A
A
V
V
E
L
G
S
F
D
A
A
A
E
R
L
H
V
T
P
S
A
V
S
Q
R
I
K
S
L
E
Q
Q
V
G
Q
V
L
V
V
R
-
E
K
P
C
R
A
T
T
A
G
I
P
L
L
R
L
A
A
Q
T
A
L
-
L
E
S
E
A
L
A
E
---
M
G
A
---
S
--
L
K
R
T
----
R
I
T
I
A
V
N
-
A
-
D
S
M
A
T
W
F
S
A
V
F
D
G
L
G
D
V
L
L
D
V
R
I
E
D
Q
D
---
H
S
A
R
---
L
L
R
----
E
G
V
A
M
G
A
V
---
T
T
E
R
N
P
---
V
P
G
C
R
V
H
P
L
-
G
E
M
R
-
Y
L
P
V
A
S
R
P
F
V
Q
R
H
L
-
S
D
G
F
T
A
A
A
A
A
K
A
P
-
S
L
A
W
N
R
D
D
-----
G
-
L
Q
D
M
-
L
V
R
K
A
F
-
R
R
-
A
I
T
R
P
--
T
-
H
F
----
V
P
T
T
E
G
-
F
T
A
-
A
A
R
A
-
G
L
G
W
G
M
-
F
P
E
K
L
-
A
A
S
P
L
A
D
G
S
F
---
V
-
R
V
C
D
I
H
L
-
D
-
V
P
-
L
Y
W
Q
C
W
K
L
D
S
P
I
I
A
R
I
-
T
D
T
V
R
A
A
A
S
G
L
Y
R
G
Q
--
36
HHSearch
61.90
22%
-97
- C3 -
3MZ1
-
?
A:
[85-293]
-----------------------------------------------------------------------------------------------------
L
P
K
G
----
R
L
R
V
E
T
A
-
S
-
A
F
A
N
L
V
I
I
P
A
L
P
E
F
H
K
K
Y
P
D
I
Q
I
D
L
G
V
---
S
D
R
T
----
Y
L
----
A
E
N
V
D
C
A
I
---
R
A
G
T
L
T
---
D
Q
S
L
I
A
R
R
I
-
T
E
M
K
-
F
V
A
C
A
S
R
D
F
L
E
R
-
H
-
P
V
P
Q
H
P
S
D
L
E
K
N
C
-
Y
V
V
G
Y
F
L
-
P
K
--
Q
Q
-
M
P
F
H
-
F
R
R
G
N
E
-
E
I
E
V
S
G
R
Y
--
T
-
M
A
----
A
N
E
S
T
T
-
Y
L
A
-
A
A
R
A
-
G
L
G
V
I
Q
-
A
P
L
F
M
-
V
R
E
D
L
R
N
G
T
M
---
V
-
P
V
L
P
D
W
Q
-
V
-
E
P
-
M
P
I
Y
L
V
Y
P
P
N
R
H
L
S
S
R
-
L
R
V
F
A
D
W
V
V
K
V
M
A
Q
S
Q
N
55
Fugue
60.98
21%
-111
* C3 *
3HHF
1
?
A:
[5-207]
------------------------------------------------------------------------------------------------------
P
Q
G
----
V
L
S
V
D
S
A
M
P
M
V
L
H
L
--
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
---
S
E
G
Y
---
I
N
L
I
---
E
R
K
V
D
I
A
L
---
R
A
G
E
L
D
---
D
S
G
L
R
A
R
H
L
-
F
D
S
R
-
F
R
V
I
A
S
P
E
Y
L
A
K
-
H
-
G
T
P
Q
S
T
E
E
L
A
G
H
Q
-
C
L
G
F
T
E
P
G
S
L
N
T
W
A
-
V
L
D
A
-
Q
G
-----
N
P
-
Y
K
I
S
P
--
H
-
F
T
----
A
S
S
G
E
I
-
L
R
S
-
L
C
L
S
-
G
C
G
I
V
C
-
L
S
D
F
L
-
V
D
N
D
I
A
E
G
K
L
---
I
-
P
L
L
A
E
Q
T
-
S
-
D
K
T
H
P
F
N
A
V
Y
Y
S
D
K
A
V
N
L
R
-
L
R
V
F
L
D
F
L
V
E
E
L
G
----
50
Fugue
59.72
22%
-104
- C3 -
3KOS
9
AMPR_CITFR
A:
[11-210]
-------------------------------------------------------------------------------------------------------
Q
E
----
K
L
K
I
G
V
V
-
G
-
T
F
A
I
G
C
L
F
P
L
L
S
D
F
K
R
S
Y
P
H
I
D
L
H
I
S
T
---
H
N
N
R
---
V
D
P
A
---
A
E
G
L
D
Y
T
I
---
R
Y
G
G
G
A
---
W
H
D
T
D
A
Q
Y
L
-
C
S
A
L
M
S
-
P
L
C
S
P
T
L
A
S
Q
-
I
-
Q
---
T
P
A
D
I
L
K
F
P
-
L
L
R
S
Y
R
R
D
-----
E
-
W
A
L
W
M
Q
T
V
G
E
A
-
P
P
-
S
P
T
H
N
--
V
M
V
-----
F
D
S
S
V
T
M
L
E
A
-
A
Q
A
G
M
G
V
A
I
A
P
----
V
R
M
F
T
H
L
L
S
S
E
R
I
---
V
-
Q
P
F
L
T
Q
--
I
-
D
L
-
G
S
Y
W
I
T
R
L
Q
S
R
P
E
T
P
A
M
R
-
E
F
S
R
W
L
T
G
V
L
H
K
T
--
2
PsiBlast_PDB
59.29
27%
-134
- C3 -
3KOT
5
AMPR_CITFR
A:
[11-173]
-------------------------------------------------------------------------------------------------------
Q
E
----
K
L
K
I
G
V
V
-
G
-
V
F
A
I
G
C
L
F
P
L
L
S
D
F
K
R
S
Y
P
H
I
D
L
H
I
S
T
---
H
N
N
R
---
V
D
P
A
---
A
E
G
L
D
Y
T
I
---
R
Y
G
G
G
A
---
W
H
D
T
D
A
Q
Y
L
-
C
S
A
L
-
M
S
P
L
C
S
P
T
L
A
S
Q
-
I
-
Q
T
P
---
A
D
I
L
K
F
P
-
L
L
-----
R
S
Y
R
R
D
E
-
W
-
A
L
-
W
M
Q
T
V
G
-
E
A
-
P
P
S
P
T
HN
V
-
M
V
----
F
D
S
A
V
T
-
M
L
E
-
A
A
Q
A
-
G
M
G
V
A
I
-
A
P
V
R
M
-
F
T
H
L
L
S
S
E
R
I
---
V
-
Q
P
F
L
T
Q
I
-
D
-
L
G
-
S
F
W
I
T
R
L
Q
S
R
P
E
T
P
A
M
-
R
E
F
S
R
W
L
T
G
V
L
H
-----
4
PsiBlast_PDB
57.64
27%
-134
- C3 -
3KOS
9
AMPR_CITFR
A:
[11-173]
-------------------------------------------------------------------------------------------------------
Q
E
----
K
L
K
I
G
V
V
-
G
-
T
F
A
I
G
C
L
F
P
L
L
S
D
F
K
R
S
Y
P
H
I
D
L
H
I
S
T
---
H
N
N
R
---
V
D
P
A
---
A
E
G
L
D
Y
T
I
---
R
Y
G
G
G
A
---
W
H
D
T
D
A
Q
Y
L
-
C
S
A
L
-
M
S
P
L
C
S
P
T
L
A
S
Q
-
I
-
Q
T
P
---
A
D
I
L
K
F
P
-
L
L
-----
R
S
Y
R
R
D
E
-
W
-
A
L
-
W
M
Q
T
V
G
-
E
A
-
P
P
S
P
T
H
N
V
-
M
V
----
F
D
S
S
V
T
-
M
L
E
-
A
A
Q
A
-
G
M
G
V
A
I
-
A
P
V
R
M
-
F
T
H
L
L
S
S
E
R
I
---
V
-
Q
P
F
L
T
Q
I
-
D
-
L
G
-
S
Y
W
I
T
R
L
Q
S
R
P
E
T
P
A
M
-
R
E
F
S
R
W
L
T
G
V
L
H
K
T
---
30
HHSearch
52.93
18%
-118
- C3 -
1UTH
12
?
A:
[94-310]
----------------------------------------------------------------------------------------
T
---
R
N
S
F--
D
PF
A
S
T
R
----
T
F
N
L
A
M
T
-
D
-
I
G
E
M
Y
F
M
P
P
L
M
E
A
L
A
Q
R
A
P
H
I
Q
I
S
T
L
R
---
P
N
A
G
N
L
K
E
D
M
E
---
S
G
A
V
D
L
A
L
---
G
L
L
P
E
L
---
Q
T
G
F
F
Q
R
R
L
-
F
R
H
R
-
Y
V
C
M
F
R
K
D
H
P
S
A
-
K
-
S
-
P
M
S
L
K
Q
F
S
E
L
E
-
H
V
G
V
V
A
L
N
-
T
G
H
G
E
-
V
D
G
L
-
L
E
R
A
G
I
-
K
----
R
R
M
--
R
-
L
V
----
V
P
H
F
I
A
-
I
G
P
-
I
L
H
S
-
T
D
L
I
A
T
-
V
P
Q
R
F
-
A
V
R
C
E
V
P
F
G
L
---
T
-
T
S
P
H
P
A
K
-
L
-
P
D
-
I
A
I
N
L
F
W
H
A
K
Y
N
R
D
P
G
-
N
M
W
L
R
Q
L
F
V
E
L
F
S
E
A
H
H
46
HHSearch
52.64
17%
-115
- C3 -
2FYI
-
CBL_ECOLI
A:
[90-296]
-----------------------------------------------------------------------------------------------------
D
T
S
G
----
V
L
T
I
A
T
T
-
H
-
T
Q
A
R
Y
S
L
P
E
V
I
K
A
F
R
E
L
F
P
E
V
R
L
E
L
I
Q
---
G
T
P
Q
E
I
A
T
L
L
Q
---
N
G
E
A
D
I
G
I
---
A
S
E
R
L
S
N--
D
P
Q
L
V
A
F
P
W
-
F
R
W
H
-
H
S
L
L
V
P
H
D
H
P
L
T
-
Q
-
I
S
P
L
T
L
E
S
I
A
K
W
P
-
L
I
T
Y
R
Q
G
-
I
T
G
R
S
R
-
I
D
D
A
-
F
A
R
K
G
L
-
L
----
A
D
I
--
V
-
L
S
----
A
Q
D
S
D
V
-
I
K
T
-
Y
V
A
L
-
G
L
G
I
G
L
-
V
A
E
Q
S
-
S
G
E
Q
-
E
E
E
N
L
---
I
-
R
L
D
T
R
H
L
-
F
-
D
A
-
N
T
V
W
L
G
L
K
R
G
Q
L
Q
R
N
Y
-
V
W
R
F
L
E
L
C
N
A
G
L
S
V
E
D
I