@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0063: (2015-12-20 )
MLVGRRAVRVLCYVPPMPRRLRHPLADLRLPRWVPCLALLALSGCSTVSYYGQLASGQFALLRAREPAAAVIADPQRDARLRERLAKAEKARQFASERLGLPDNRSYRLYADIGRPYVVWNVFATPELSLQPVTHCFPIAGCVAYRGYYSEAAARAEAARQRALGDDVYVGGVQAYSTLGWFDDPILSSMLRWDDERLATLIFHELAHQKFYLRDDTAFNESFATFVEQEGTRQWREYRGLPPADGREEKRREQFTALVLASRARLEALYAGPLDDAAKRAGKAAEFQRLRREYAALSQREWGGESPFKAWIDAPFNNAKLLPFGLYDQWVAAFAVLFRQVGGNWPAFYARVRALGQLPLAERQAALQRLAAAAP
Atome Classification :
(20 SA)
----.........10.......----.20........30.......---.40...-.....50........60--...-----.--------.-...70-..-......80-........90..--......100.......110.......120-....-...130....-...140.......150-----...-....160.......170.......----180.....--..190.....--..200........210-----.------.......220.......230.......240.......250.....--..260..--.......270-------..--..-----------.-------...280...-...-.290...-....300-----........310........320........330.......340.-----..---.-..----..350.......360.......370...--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----MLVG
R
R
A
V
R
V
L
C
YVPPM
P
----
R
R
L
RH
P
L
A
DLRLP
R
W
V
P
C
L
A
---
L
L
A
LSG-C
S
T
V
S
Y
Y
G
QLASG
Q
F
A
L
--
L
RA-----R--------E-P
A
A
A
V
-
I
A-DP
Q
R
D
A
R
L
-
R
E
R
L
A
K
A
E
K
A
R
Q
--
F
A
S
E
RLGLPDNR
S
Y
R
L
Y
A
DIGR
P
Y
V
V
W
N
V-FATP-ELSLQPV
T
H
C
-
F
P
I
A
G
C
V
A
Y
R
G
Y
Y
S
E
A
-----
A
A
R
-
A
E
A
A
R
Q
RALGDD
V
Y
VG
G
V
Q
A
Y
STL----GWFD
D
P
I
L
--
S
S
M
LRW
D
D
E
R
--
L
A
T
-
L
I
F
H
E
L
A
H
Q
K
F
------
Y
------LRDDTAF
N
E
S
F
A
T
F
V
E
Q
E
G
T
R
Q
W
R
E
YRGLPPAD
G
R
E
E
K
R
R
E
Q
F
T
A
--
L
V
L
--
A
S
--
R
A
R
L
E
A
L
YA--------GP--L
D
-----------
D
-------
A
A
K
RAG
K
A
A
-
E
F
Q
-
R
L
R
R
E
Y
A
-
A
L
S
Q
RE------WGGES
P
F
K
A
-
W
IDAPFNN
A
K
L
-
L
P
F
G
L
Y
D
Q
W
V
A
A
F
A
V
L
F
R
Q-VG-----GN---
W
-
P
A
----
F
Y
A
R
V
R
A
LGQLP
L
A
E
R
Q
A
A
L
Q
R
L
AAAAP--------
29
HHSearch
75.75
17%
-20
- C4 -
1Z5H
3
TRF3_THEAC
A:
[158-418]
----------------------------------------------------------
M
S
T
Y
L
L
Y
V
G
I
G
K
F
R
Y
--
E
Y
E
-----
K
--------
Y
R
D
I
D
L
I
-
L
A
-
S
--
L
K
D
-----------
I
R
S
K
--
Y
P
L
D
-
M
A
R
K
S
V
E
F
Y
E
N
Y
F
G
I
P
Y
A
L
P
K
M
H
L
-
I
S
V
P
-
E
F
G
A
G
A
M
E
N
W
-----
G
A
I
T
F
R
----------------
E
I
Y
M
-------------------------
D
I
A
E
N
---
S
A
V
--
T
V
K
R
N
--
S
A
N
-
V
I
A
H
E
I
A
H
Q
W
F
------
G
DLVTMK
W
W
N
D
L
W
L
N
E
S
F
A
T
F
M
S
Y
K
T
M
D
T
L
F
P
E
----------
W
S
F
W
G
D
F
F
V
--
S
R
T
--
S
G
--
A
L
R
S
D
S
L
K
N
--------
T
H
--
P
I
EVDVRD-----
P
DEISQIF
D
E
I
S
Y
G
K
G
A
S
I
L
R
-
M
I
E
D
Y
A
G
-
Y
E
E
--
F
------
R
K
G
I
S
K
Y
L
N
D
H
K
F
G
---
N
-----------
A
E
G
S
D
L
W
T
A
I
E
D
V
S
G
-----
K
P
---
V
-
K
R
----
V
M
E
Y
W
I
K
N
P
G
Y
P
V
I
K
L
K
R
N
G
R
K
I
T
M
Y
Q
T
--------
47
Fugue
71.46
15%
-66
- C3 -
3TUZ
3
METN_ECOLI
H:
[23-362]
----
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
----
I
Q
A
L
N
N
-
V
S
L
H
V
P
A
G
-
Q
I
Y
G
---
V
I
G
A
S
G
-
A
-----------
G
K
S
T
L
--
I
R
C
VNLLE
R
--------
P
-
T
E
G
S
V
-
L
V
-
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
I
G
--
M
I
F
Q
H
F
N
L
L
S
S
R
T
--
V
F
G
N
V
A
L
P
L
E
L
D
N
T
---
P
K
-
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
G
D
K
H
D
S
Y
P
S
N
LSGGQ
K
Q
R
-
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
----
P
A
T
T
R
S
I
L
--
E
L
L
K
D
I
N
R
R
L
GL
T
I
L
-
L
I
T
H
E
M
D
V
V
K
R
------
I
------
C
-
D
C
V
A
V
I
S
N
-
G
E
L
I
E
Q
----------------------------------------
D
T
V
S
E
V
F
S
--------
H
P
--
K
T
-----------
P
-------
L
A
Q
K
F
I
Q
S
T
-
L
H
L
-
D
I
P
E
D
Y
Q
-
E
R
L
Q
A
E
------
P
F
T
D
C
--
V
P
-
M
L
R
L
E
F
T
G
Q
S
V
-
D
A
-
P
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
-
I
S
-----
A
Q
---
M
-
D
Y
----
A
G
G
V
K
F
G
I
M
L
T
E
M
H
G
T
Q
Q
D
T
Q
A
A
I
A
W
L
Q
EHHVKVEV
44
Fugue
70.34
18%
-40
- C2 -
3WO4
7
IL18R_HUMAN
B:
[1-301]
----
G
P
E
S
C
T
S
R
P
H
I
T
V
V
E
G
E
P
----
F
Y
L
K
H
------------
C
----------
S
-
C
S
L
A
H
---
E
I
E
T
T
T
K
S
W
--
Y
K
S
-----
S
--------
G
-
S
Q
E
H
V
-
E
L
-
N
P
R
S
S
S
R
I
-
A
L
H
----
D
C
V
L
E
--
F
W
P
--
V
E
L
N
D
T
G
S
Y
F
F
Q
M
K
N
Y
T
Q
K
W
K
L
N
V
-
I
R
R
N
-
K
H
S
------
C
-
F
T
----------------------------
E
R
Q
V
T
S
K
I
V
E
--
V
K
K
F
F
Q
I
T
CEN
S
Y
Y
Q
T
L
V
N
--
S
T
S
L
Y
K
N
C
K
K
--
L
L
L
-
E
N
N
K
N
P
T
I
K
K
N
------
A
------
E
F
E
D
Q
G
Y
Y
-
S
C
V
H
F
L
H
H
---------------
N
G
K
L
F
N
I
T
K
T
F
N
I
--
T
I
V
--
E
D
--
R
S
N
I
V
P
V
L
L
--------
G
P
K-
L
N
-----------
H
-------
V
A
V
E
L
G
K
-------
N
V
R
L
N
C
S
-
A
L
L
N
E
E
D
V
I
Y
W
M
F
G
E
E
N
G
S
D
P
-
N
I
H
E
E
K
E
M
R
I
M
-
T
P
E
G
---
K
W
H
A
S
K
V
L
R
I
E
N
-
I
G
-----
E
S
---
N
-
L
N
----
V
L
Y
N
C
T
V
A
S
T
G
G
T
D
T
K
S
F
I
L
V
R
K
A
D
-----------
46
Fugue
69.52
16%
-43
- C3 -
3ASM
-
?
A:
[2-309]
----------
S
N
Y
V
I
Q
A
D
Q
Q
L
L
----
D
A
L
R
A
H
Y
E
G
A
L
S
D
R
L
P
A
G
A
L
---
F
A
V
K
R
P
-
D
V
V
I
T
A
Y
R
---
S
G
K
V
L
F
A
G
K
A
A
-----
E
--------
Q
-
E
A
A
K
W
-
I
S
-
G
A
S
A
S
N
E
T
-
A
D
H
Q
P
S
A
L
A
A
H
Q
--
L
G
S
-----------------------
L
S
A
-
I
G
S
D
-
E
V
-------------
G
T
G
D
Y
F
G
P
I
V
V
A
-----
A
A
Y
-
V
D
R
P
H
I
A
K
I
A
A
------------
L
----
G
V
K
D
S
K
Q
L
--
N
---
D
E
A
I
K
R
--
I
A
P
-
A
I
M
E
T
V
P
H
A
V
T
------
V
------
L
D
-
N
P
Q
Y
N
R
W
Q
R
S
G
M
P
Q
T
K
M
K
A
L
L
H
N
R
T
L
V
K
L
V
D
A
I
A
P
A
E
---
P
E
--
A
I
I
--
I
D
--
E
F
L
K
R
D
S
Y
F
--------
R
Y
--
L
S
-----------
D
-------
E
D
R
I
I
R
E
R
V
-
H
C
L
P
K
A
E
S
V
H
V
-
S
V
A
A
A
S
------
I
I
A
R
Y
V
F
L
E
-
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
R
A
-
R
G
-------------------
E
E
M
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
R
R
----------
33
HHSearch
58.96
13%
-29
- C4 -
3CIA
1
?
A:
[149-458]
-------
H
A
R
S
W
I
P
I
Q
D
T
P
S
V
R
V
T
Y
T
A
R
I
T
T
D
K
D
L
L
A
V
M
S
A
N
N
E
--RDG
D
Y
F
F
S
M
P
Q
A
I
P
P
Y
L
I
A
I
G
V
G
D
L
E
F
--
K
A
M
-----
S
--------
H
--
Q
T
G
I
-
Y
A
-
E
S
Y
I
L
D
A
A
------------
V
--
A
E
F
D
-
D
T
Q
A
M
I
D
K
A
E
Q
M
Y
G
-
K
Y
R
W
G
R
Y
D
L
-
L
M
L
P
P
S
F
P
F
G
G
M
E
N
P
-----
R
L
S
F
I
T
----------------
P
T
V
V
--------------------------------------
A
G
D
K
S
--
L
V
N
-
L
I
A
H
E
L
A
H
S
W
S
------
G
NLVTNE
S
W
R
D
L
W
L
N
E
G
F
T
S
Y
V
E
N
R
I
M
E
A
V
F
G
T
D
R
A
--
V
M
-------
E
Q
A
L
G
A
Q
D
L
N
--
A
E
--
I
L
E
L
D
A
S
D
T
QLYIDLKG
R
D
--
P
D
DA---------
F
-------
S
G
V
P
Y
V
K
G
Q
L
F
L
M
-
Y
L
E
E
K
F
G
-
R
E
R
--
F
------
D
A
F
V
L
E
Y
F
D
S
H
A
F
Q
---
S
-----------
L
G
T
D
N
F
V
K
Y
L
K
A
N
L
T
DKYPN
I
V
---
S
-
D
N
----
E
I
N
E
W
I
F
K
A
G
L
P
S
Y
A
P
Q
P
T
S
N
A
F
K
V
I
D
K
--------
49
Fugue
57.17
11%
-52
- C3 -
2HLZ
6
KHK_HUMAN
A:
[17-312]
GS
Q
I
L
C
V
G
L
V
V
L
D
V
I
S
L
V
D
K
Y
P
----
K
E
D
S
E
I
R
C
L
----------------------
S
Q
R
W
Q
R
G
G
N
A
S
N
S
C
T
I
--
L
S
L
-----
L
--------
G
-
A
P
C
A
F
M
G
S
M
A
P
G
H
V
A
D
F
-
V
L
D
D
L
R
R
Y
S
V
D
L
RY
T
V
F
Q
T
T
G
S
V
P
I
A
T
V
I
I
N
E
A
S
G
S
R
T
I
L
Y
Y
D
-
R
S
L
P
-
D
V
S
A
T
D
F
E
K
V
D
L
T
Q
F
K
W
I
H
I
E
G
R
N
A
S
E
-----
Q
V
K
M
L
Q
R
I
D
A
H
N
T
---------------------------------
R
Q
P
P
E
Q
--
K
I
R
-
V
S
V
E
V
--------------------
E
K
P
R
E
E
L
F
Q
L
F
G
Y
G
D
-------------------------------
V
V
F
--
V
S
--
K
D
V
A
K
H
L
G
F
--------
Q
S
--
A
E
-----------
E
-------
A
L
R
G
L
Y
G
R
V
-
R
K
G
-
A
V
L
V
C
A
W
-
A
E
E
G
A
D
------
A
L
G
P
D
G
K
L
L
-
H
S
D
A
F
P
P
P
R
V
V
-
D
T
L
G
A
G
D
T
F
N
A
S
V
I
F
S
L
S
Q
---------------------
G
R
S
V
Q
E
A
L
R
F
G
C
Q
V
A
G
K
K
C
G
L
Q
G
F
D
G
I
V
--------
31
HHSearch
57.11
11%
-19
- C4 -
3B34
9
AMPN_ECOLI
A:
[203-468]
----------------------------------------------------------
K
P
C
Y
L
F
A
L
V
A
G
D
F
D
V
--
L
R
D
-----
T
F
T
T
RS
G
R
E
V
-
A
L
E
-
L
-
Y
V
-
D
R
G
N
L
D
------------
R
A
P
--
W
A
M
T
-
S
L
K
N
S
M
K
W
D
E
E
R
F
G
L
E
Y
D
L
D
I
Y
M
I
-
V
A
V
D
-
F
F
N
M
G
A
M
E
N
K
-----
G
L
N
I
F
N
----------------
S
K
Y
V
-------------------------
L
A
R
T
D
T
--
A
T
D
--
K
D
Y
L
D
--
I
E
R
-
V
I
G
H
E
Y
F
H
N
W
T
------
G
NRVTCR
D
W
F
Q
L
S
L
K
E
G
L
T
V
F
R
D
Q
E
F
S
S
D
L
G
S
R
A
V
--
N
R
I
N
N
V
R
T
----------
M
R
--
G
L
--
Q
F
A
E
D
A
S
P
M
--------
A
H
--
P
I
RPDMVIEMNNF
Y
-------
T
L
T
V
Y
E
K
G
A
E
V
I
R
-
M
I
H
T
L
L
G
-
E
E
N
--
F
------
Q
K
G
M
Q
L
Y
F
E
R
H
D
G
S
---
A
-----------
A
T
C
D
D
F
V
Q
A
M
E
D
A
S
N
-----
V
D
---
L
-
S
H
----
F
-
R
R
W
Y
S
Q
S
G
T
P
I
V
T
V
K
D
D
Y
N
P
E
T
E
Q
Y
T
--------
32
HHSearch
56.31
9%
-31
- C4 -
3U9W
5
LKHA4_HUMAN
A:
[195-453]
----------------------------------------------------------
I
P
C
Y
L
I
A
L
V
V
G
A
L
E
S
--
R
Q
I
-----
G
--------
P
-
R
T
-
L
V
-
W
S
-
E
K
E
Q
V
E
K
------------
S
A
--
Y
E
F
S
-
E
T
E
S
M
L
K
I
A
E
D
L
G
G
-
P
Y
V
W
G
Q
Y
D
L
-
L
V
L
P
P
S
F
P
Y
G
G
M
E
N
P
-----
C
L
T
F
V
T
----------------
P
T
-
L
-------------------------
L
A
------------
G
D
K
S
--
L
S
N
-
V
I
A
H
E
I
S
H
S
W
T
------
G
NLVTNK
T
W
D
H
F
W
L
N
E
G
H
T
V
Y
L
E
R
H
I
C
G
R
L
F
G
E
K
F
R
--
H
F
N
A
-
L
G
G
W
G
E
L
Q
N
--
S
V
K
T
F
G
E
--
T
H
P
F
T
K
L
V
V
DLTD----
I
D
PD
V
A
-----------
Y
-------
S
S
V
P
Y
E
K
G
F
A
L
L
F
-
Y
L
E
Q
L
L
G
G
P
E
I
--
F
------
L
G
F
L
K
A
Y
V
E
K
F
S
Y
K
---
S
-----------
I
T
T
D
D
W
K
D
F
L
Y
S
Y
F
K
-----
D
K
---
V
-
D
V
L
N
Q
V
D
W
N
A
W
L
Y
S
P
G
L
P
P
I
K
P
N
Y
D
M
T
L
T
N
A
C
I
A
--------
34
HHSearch
50.28
11%
-28
- C4 -
2XQ0
3
LKHA4_YEAST
A:
[202-462]
----------------------------------------------------------
I
P
A
Y
L
I
G
I
A
S
G
D
L
S
S
--
A
P
I
-----
G
--------
P
-
R
S
T
-
V
-
Y
T
-
E
P
F
R
L
K
D
C
------------
Q
--
W
E
F
E
N
D
V
E
K
F
I
Q
T
A
E
K
I
I
F
-
E
Y
E
W
G
T
Y
D
I
L
V
N
V
D
-
S
Y
P
Y
G
G
M
E
S
P
-----
N
M
T
F
A
T
-----------------
P
T
L
-------------------------
L
A
------------
H
D
R
S
--
N
I
D
-
V
I
A
H
E
L
A
H
S
W
S
------
G
NLVTNC
S
W
N
H
F
W
L
N
E
G
W
T
V
Y
L
E
R
R
I
I
G
A
I
H
G
E
P
T
R
--
H
F
S
A
-
L
I
G
W
S
D
L
Q
N
--
S
I
D
--
S
M
KD
P
E
R
F
S
T
L
V
Q
N
L
N
DN---
T
D
--
P
D
DA---------
F
-------
S
T
V
P
Y
E
K
G
F
N
L
L
F
-
H
L
E
T
I
L
G
-
G
K
A
-
E
F
------
D
P
F
I
R
H
Y
F
K
K
F
A
K
K
---
S
-----------
L
D
T
F
Q
F
L
D
T
L
Y
E
F
Y
P
-----
E
K
K
E
I
L
D
S
V
----
D
W
E
T
W
L
Y
K
P
G
M
P
P
R
P
H
F
I
T
A
L
A
D
N
V
Y
Q
L
--------
1
PsiBlast_PDB
48.63
37%
-6
- C4 -
4FYQ
4
AMPN_HUMAN
A:
[294-357]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
V
T
Y
R
E
N
----
S
L
L
F
D
P
L
S
--
S
S
S
S
--
N
K
E
R
--
V
V
T
-
V
I
A
H
E
L
A
H
Q
W
F
GNLVTI
E
------
W
W
N
D
L
W
L
N
E
G
F
A
S
Y
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
K
D
L
M
V
L
N
D
V
Y
R
V
M
A
V
D
--
A
L
A
--
S
S
--
H
P
L
S
T
P
A
S
E
--------
I
N
--
T
P
-----------
A
-------
Q
I
S
E
L
F
D
A
I
-
S
Y
S
-
K
G
A
S
V
L
R
-
M
L
S
S
F
L
------
S
E
D
V
F
K
Q
G
L
-
A
S
Y
L
H
T
F
A
Y
Q
N
-
T
I
Y
L
N
L
W
D
H
L
Q
E
A
V
N
N
R
S
I
-
Q
L
-----
P
T
---
T
-
V
R
----
D
I
M
N
R
W
T
L
Q
M
G
F
P
V
I
T
V
D
T
S
T
G
T
L
S
Q
E
H
--------
4
PsiBlast_PDB
47.77
37%
-10
- C4 -
4FYT
4
AMPN_HUMAN
A:
[294-357]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
V
T
Y
R
E
N
----
S
L
L
F
D
P
L
S
--
S
S
S
S
--
N
K
E
R
--
V
V
T
-
V
I
A
H
E
L
A
H
Q
W
F
GNLVTI
E
------
W
W
N
D
L
W
L
N
E
G
F
A
S
Y
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
K
D
L
M
V
L
N
D
V
Y
R
V
M
A
V
D
--
A
L
A
--
S
S
--
H
P
L
S
T
P
A
S
E
--------
I
N
--
T
P
-----------
A
-------
Q
I
S
E
L
F
D
A
I
-
S
Y
S
-
K
G
A
S
V
L
R
-
M
L
S
S
F
L
------
S
E
D
V
F
K
Q
G
L
-
A
S
Y
L
H
T
F
A
Y
Q
N
-
T
I
Y
L
N
L
W
D
H
L
Q
E
A
V
N
N
R
S
I
-
Q
L
-----
P
T
---
T
-
V
R
----
D
I
M
N
R
W
T
L
Q
M
G
F
P
V
I
T
V
D
T
S
T
G
T
L
S
Q
E
H
--------
2
PsiBlast_PDB
47.28
37%
-13
- C4 -
4FYR
4
AMPN_HUMAN
A:
[294-357]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
V
T
Y
R
E
N
----
S
L
L
F
D
P
L
S
--
S
S
S
S
--
N
K
E
R
--
V
V
T
-
V
I
A
H
E
L
A
H
Q
W
F
GNLVTI
E
------
W
W
N
D
L
W
L
N
E
G
F
A
S
Y
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
K
D
L
M
V
L
N
D
V
Y
R
V
M
A
V
D
--
A
L
A
--
S
S
--
H
P
L
S
T
P
A
S
E
--------
I
N
--
T
P
-----------
A
-------
Q
I
S
E
L
F
D
A
I
-
S
Y
S
-
K
G
A
S
V
L
R
-
M
L
S
S
F
L
------
S
E
D
V
F
K
Q
G
L
-
A
S
Y
L
H
T
F
A
Y
Q
N
-
T
I
Y
L
N
L
W
D
H
L
Q
E
A
V
N
N
R
S
I
-
Q
L
-----
P
T
---
T
-
V
R
----
D
I
M
N
R
W
T
L
Q
M
G
F
P
V
I
T
V
D
T
S
T
G
T
L
S
Q
E
H
--------
3
PsiBlast_PDB
45.92
37%
-5
- C4 -
4FYS
2
AMPN_HUMAN
A:
[294-357]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
V
T
Y
R
E
N
----
S
L
L
F
D
P
L
S
--
S
S
S
S
--
N
K
E
R
--
V
V
T
-
V
I
A
H
E
L
A
H
Q
W
F
GNLVTI
E
------
W
W
N
D
L
W
L
N
E
G
F
A
S
Y
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
K
D
L
M
V
L
N
D
V
Y
R
V
M
A
V
D
--
A
L
A
--
S
S
--
H
P
L
S
T
P
A
S
E
--------
I
N
--
T
P
-----------
A
-------
Q
I
S
E
L
F
D
A
I
-
S
Y
S
-
K
G
A
S
V
L
R
-
M
L
S
S
F
L
------
S
E
D
V
F
K
Q
G
L
-
A
S
Y
L
H
T
F
A
Y
Q
N
-
T
I
Y
L
N
L
W
D
H
L
Q
E
A
V
N
N
R
S
I
-
Q
L
-----
P
T
---
T
-
V
R
----
D
I
M
N
R
W
T
L
Q
M
G
F
P
V
I
T
V
D
T
S
T
G
T
L
S
Q
E
H
--------
27
PsiBlast_CBE
43.98
33%
-23
- C4 -
4P8Q
2
LCAP_HUMAN
B:
[271-341]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
A
G
A
M
E
N
W
G
L
L
----
T
F
R
E
E
T
L
L
YD
S
N
T
S
S
M
A
D
R
K
--
L
V
T
K
I
I
A
H
E
L
A
H
Q
W
F
GNLVTM
K
------
W
W
N
D
L
W
L
N
E
G
F
A
T
F
M
E
Y
F
S
L
E
K
I
F
K
E
L
S
S
Y
E
D
F
L
D
A
R
F
K
T
M
K
K
D
S
--
L
N
S
--
S
H
--
P
I
S
S
S
V
Q
S
S
--------
E
Q
--
I
E
-----------
E
-------
M
F
D
S
L
S
Y
F
K
-
G
S
S
-
L
L
L
M
L
K
T
-
Y
L
S
E
D
V
------
F
Q
H
A
V
V
L
Y
L
-
H
N
H
S
Y
A
S
I
Q
S
D
-
D
L
W
D
S
F
N
E
V
N
Q
T
L
D
V
K
R
M
M
-
K
T
-----
W
T
---
L
-
Q
K
----
G
F
P
L
V
T
V
Q
K
K
G
K
E
L
F
I
Q
Q
E
R
F
F
L
N
T
S
Y
L
--------
26
PsiBlast_CBE
43.41
33%
-25
- C4 -
4PJ6
2
LCAP_HUMAN
A:
[271-341]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
A
G
A
M
E
N
W
G
L
L
----
T
F
R
E
E
T
L
L
YD
S
N
T
S
S
M
A
D
R
K
--
L
V
T
K
I
I
A
H
E
L
A
H
Q
W
F
GNLVTM
K
------
W
W
N
D
L
W
L
N
E
G
F
A
T
F
M
E
Y
F
S
L
E
K
I
F
K
E
L
S
S
Y
E
D
F
L
D
A
R
F
K
T
M
K
K
D
S
--
L
N
S
--
S
H
--
P
I
S
S
S
V
Q
S
S
--------
E
Q
--
I
E
-----------
E
-------
M
F
D
S
L
S
Y
F
K
-
G
S
S
-
L
L
L
M
L
K
T
-
Y
L
S
E
D
V
------
F
Q
H
A
V
V
L
Y
L
-
H
N
H
S
Y
A
S
I
Q
S
D
-
D
L
W
D
S
F
N
E
V
T
N
Q
T
L
D
V
K
R
M
-
M
K
-----
T
W
---
T
-
L
Q
----
K
G
F
P
L
V
T
V
Q
K
K
G
K
E
L
F
I
Q
Q
E
R
F
F
L
N
M
S
D
--------
15
PsiBlast_PDB
43.29
36%
7
- C4 -
4KX9
2
AMPE_HUMAN
A:
[308-354]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
Q
R
--
V
A
T
-
V
V
A
H
E
L
V
H
Q
W
F
GNI
V
T
M
D
------
W
W
E
D
L
W
L
N
E
G
F
A
S
F
F
E
F
L
G
V
N
H
A
E
T
D
W
Q
M
R
D
Q
M
L
L
E
D
V
L
P
V
Q
E
D
D
--
S
L
M
--
S
S
--
H
P
I
I
V
T
V
T
T
--------
P
D
--
E
I
-----------
T
-------
S
V
F
D
G
I
S
Y
S
-
K
G
S
-
S
I
L
R
M
L
E
-
D
W
I
K
P
E
------
N
F
Q
K
G
C
Q
M
Y
-
L
E
K
Y
Q
F
K
N
A
K
T
-
S
D
F
W
A
A
L
E
E
A
S
R
L
P
V
K
E
V
M
-
D
T
-----
W
T
---
R
-
Q
M
----
G
Y
P
V
L
N
V
N
G
V
K
N
I
T
Q
K
R
F
L
L
D
P
R
A
N
P
S
Q
--------
28
PsiBlast_CBE
43.24
33%
-34
- C4 -
4P8Q
2
LCAP_HUMAN
A:
[271-341]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
A
G
A
M
E
N
W
G
L
L
----
T
F
R
E
E
T
L
L
YD
S
N
T
S
S
M
A
D
R
K
--
L
V
T
K
I
I
A
H
E
L
A
H
Q
W
F
GNLVTM
K
------
W
W
N
D
L
W
L
N
E
G
F
A
T
F
M
E
Y
F
S
L
E
K
I
F
K
E
L
S
S
Y
E
D
F
L
D
A
R
F
K
T
M
K
K
D
S
--
L
N
S
--
S
H
--
P
I
S
S
S
V
Q
S
S
--------
E
Q
--
I
E
-----------
E
-------
M
F
D
S
L
S
Y
F
K
-
G
S
S
-
L
L
L
M
L
K
T
-
Y
L
S
E
D
V
------
F
Q
H
A
V
V
L
Y
L
-
H
N
H
S
Y
A
S
I
Q
S
D
-
D
L
W
D
S
F
N
E
V
N
Q
T
L
D
V
K
R
M
M
-
K
T
-----
W
T
---
L
-
Q
K
----
G
F
P
L
V
T
V
Q
K
K
G
K
E
L
F
I
Q
Q
E
R
F
F
L
N
M
S
D
T
--------
51
Fugue
43.16
11%
79
* C3 *
3SJA
-
GET1_YEAST
C:
[1-61]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
L
S
K
K
Y
L
A
K
V
K
--
E
R
H
--
E
L
--
K
E
F
N
N
S
I
----------
S
A
--
Q
D
-----------
N
-------
Y
A
K
W
T
K
N
N
R
-
K
L
D
-
S
L
D
K
E
I
N
-
N
L
K
D
E
I
------
Q
S
E
N
H
H
--------------------------------------------------------------------------------------------
11
PsiBlast_PDB
43.01
42%
16
- C4 -
4F5C
1
AMPN_PIG
A:
[347-398]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
Q
S
--
S
S
I
S
--
N
K
E
R
--
V
V
T
-
V
I
A
H
E
L
A
H
Q
W
F
GNLVTL
A
------
W
W
N
D
L
W
L
N
E
G
F
A
S
Y
V
E
Y
L
G
A
D
H
A
E
P
T
W
N
L
K
D
L
I
V
P
G
D
V
Y
R
V
M
A
V
D
--
A
L
A
--
S
S
--
H
P
L
T
T
P
A
E
E
--------
V
N
--
T
P
-----------
A
-------
Q
I
S
E
M
F
D
S
I
-
S
Y
S
-
K
G
A
S
V
I
R
-
M
L
S
N
F
L
------
T
E
D
L
F
K
E
G
L
-
A
S
Y
L
H
A
F
A
Y
Q
N
-
T
T
Y
L
D
L
W
E
H
L
Q
K
A
V
D
A
Q
T
S
-
I
R
-----
L
P
---
D
-
T
V
----
R
A
I
M
D
R
W
T
L
Q
M
G
F
P
V
I
T
V
D
T
K
T
G
N
I
S
Q
K
--------
19
PsiBlast_PDB
42.99
36%
2
- C4 -
4KXD
2
AMPE_HUMAN
A:
[308-354]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
Q
R
--
V
A
T
-
V
V
A
H
E
L
V
H
Q
W
F
GNIVTM
D
------
W
W
E
D
L
W
L
N
E
G
F
A
S
F
F
E
F
L
G
V
N
H
A
E
T
D
W
Q
M
R
D
Q
M
L
L
E
D
V
L
P
V
Q
E
D
D
--
S
L
M
--
S
S
--
H
P
I
I
V
T
V
T
T
--------
P
D
--
E
I
-----------
T
-------
S
V
F
D
G
I
S
Y
S
-
K
G
S
-
S
I
L
R
M
L
E
-
D
W
I
K
P
E
------
N
F
Q
K
G
C
Q
M
Y
-
L
E
K
Y
Q
F
K
N
A
K
T
-
S
D
F
W
A
A
L
E
E
A
S
R
L
P
V
K
E
V
M
-
D
T
-----
W
T
---
R
-
Q
M
----
G
Y
P
V
L
N
V
N
G
V
K
N
I
T
Q
K
R
F
L
L
D
P
R
A
N
P
S
Q
--------