@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0079: (2015-12-20 )
MSWNNRVVWSEGMFLRPQHFQQHDRYLETLVDGRCRSLLAGGWGFSELKLDDALLTQGKLAIVSARGVLPDGTPFNIPADDPAPAPLNVEESLRDGIVYLGLPLKRVGTRDTVEEGEALGGARYVSQVQEVRDDNAAFESRAPVALGSQAFRLLTERDGLGEYAAVGVARVREKRADQALSLDEDYLPPVLDIAAAPPLASFAKELLGLLHQRGEALAGRVVASSAGGASEIADFLLLQLVNRAEALTGHLSRVRPLHPQELYRELVALAGEFCTFTASQRRPEEYPVYNHDDLAASFAPVMLALRQALATVIDAKAIAIPIVEKAYGVHVAMLSDRSLIDNASFVLVVRADVPGESLRGHFPQQAKVGSVEHIRDLVNLQLPGIGLLPMPVAPRQIPYHAGSTYFELDRGSAHWKQLTHSGGFAFHIAGQFPGLNLAFWAIRG
Atome Classification :
(20 SA)
----------------------------------------.........10........20..---......-------------30........40........50-----------------..----.-------.....60---.--........70........80........90.....------...100.......110...-----.------------...120..---------...------..130.......140.......150.-....---.----------.160......-.170.......180.....--.--------------------.190.......200.......----210......---.---220.......230......-.240.......250.......260.......270---.......-..280...------....290....-...---300---..---....-..---310-.....---....320...--------------------------.....330--.......340.----..--....------.350.......360---...-....370........--380...---.--....390.......400...-....410---------------....--.....420........430.......440..----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------MSWNN
R
V
V
WSEG
M
F
L
R
P
Q
H
F
Q
Q
H
---
D
R
Y
L
E
T
-------------
L
V
D
G
R
C
R
S
L
L
AGGWGFSELKLD-----------------
D
A
----L-------LTQG
K
L
----
A
--
I
V
S
ARGVLPDGTPFNIPADDPAPAPL
N
V
E
E
S
LRD
G
------
I
V
Y
LGL
P
L
K
RVGTRD
T
V
EE-----G------------EALG
G
A
R
Y
---------
V
S
Q
------
V
Q
E
VRDDNAAFESRAPV
A
L
G
S
Q
A
F
R
L
-
L
T
ER---D----------GL
G
E
Y
A
A
V
G
V
-
A
R
V
R
E
K
RADQALSLDEDYL--P--------------------
P
V
L
DIAAAP
P
L
A
S
F
A
K
E
L
L
G
L
----
L
H
QR
G
E
A
L
A---
G
---
R
V
V
ASSAG
G
A
S
E
I
A
D
F
L
L
L
-
Q
L
V
N
R
A
E
A
L
T
G
H
L
S
RVRPL
H
P
Q
E
L
Y
R
E
L
V
A
L
A
-----
G
E
F
C
TFT-ASQRRPEE------YPVYN
H
D
D
L
A
A
-
S
F
A
---
P
V
----
M
L
---
A
L
R
Q
-
A
L
---
A
---
T
V
IDA---K
A
I
A
I
P
-
I
V
E--------------------------KAY
G
V
H
V
A
--
M
LSDRSLID-N----A
S
--
F
V
L
V
------
V
RADVP
G
E
S
L
RGHF---PQQ-AKVG
S
-
V
E
H
I
R
D
L
V
N--L-QLPG---I--GLLPMPVAPRQIPYHAGS
T
Y
-
F
E
LDR-----------------GS
A
H
--
W
K
Q
L
TH-SG
G
F
A
F
H
I
AGQFPG
L
N
L
A
F
W
A
IRG----------------------
16
Fugue
91.76
18%
-52
- C6 -
4Q6O
8
?
A:
[21-437]
----------------------------------------
M
-----------
I
E
K
A
P
T
N
V
E
D
R
---
D
K
A
P
H
L
-------------
L
L
L
A
G
I
Q
G
D
E
P
G
G
F
N
A
T
N
L
F
L
M
-----------------
H
Y
----
S
-------
V
L
K
G
L
V
----
E
--
V
V
P
V
---------------------
L
N
K
P
S
M
L
R
N
H
------------------------
R
-----
G
------------
L
Y
G
D
M
N
R
K
---------
F
A
A
------
L
D
K
N
D
P
E
Y
P
T
I
Q
E
I
K
S
L
I
A
K
P
S
I
D
A
V
-
L
H
L
H
---
D
----------
G
G
G
Y
Y
R
P
V
Y
V
D
A
M
L
N
P
K
R
W
G
N
C
F
I
I
D
Q
D
E
V
--
K
--------------------
G
----
A
K
F
P
N
L
L
A
F
A
N
N
T
I
E
S
----
I
N
A
H
L
L
H
P
I
E
E
Y
H
---
L
K
N
T
R
T
A
Q
G
D
T
E
M
Q
K
A
L
T
F
-
Y
A
I
N
Q
K
K
S
A
F
A
N
E
A
S
K
E
L
P
L
A
S
R
V
F
Y
H
L
Q
A
I
E
-----
G
L
L
N
Q
L
N
-
I
P
F
K
R
D
F
D
LN
P
N
S
V
H
A
L
I
N
D
K
N
L
W
A
-
K
I
S
---
S
L
PKMP
L
F
---
N
L
R
P
-
K
L
NH
F
P
---
L
P
H
N
T
---
K
I
P
Q
I
P
-
I
E
S
--------------------------
N
A
Y
I
V
G
L
V
--
K
N
K
Q
E
V
F
L
K
-
Y
----
G
N
--
K
L
M
T
RLS
P
F
Y
I
E
F
D
P
S
L
E
E
V
K
M
Q
I
DN
K
D
Q
M
-
V
K
I
G
S
-
V
V
E
V
K
E
S
F
Y
--
I
-
H
A
M
D
N
I
R
A
--
N
V
I
G
F
S
V
S
N
E
N
K
P
N
E
A
G
Y
T
I
K
F
K
D
F
Q
-----------------
K
R
F
S
--
L
D
K
Q
E
R
-
I
Y
R
I
E
F
Y
K
N
N
A
F
S
G
M
I
L
V
K
F
V
-------------------------
22
Fugue
87.36
18%
-44
- C5 -
5C8T
5
?
B:
[2-526]
-------------------------------------AEN
V
T
G
L
F
K
D
C
S
K
I
I
T
G
L
H
P
T
Q
A
P
T
H
LSV
D
I
K
F
K
T
EG
L
C
V
D
I
PGIPKD
M
T
Y
R
R
L
I
S
M
M
G
F
K
M
N
Y
Q
V
N
G
Y
P
-----------------
N
M
----
F
-------
I
T
R
E
E
A
----
I
R
H
V
R
A
W
I
G
F
D
V
E
G
C
H
A
T
R
D
A
V
G
T
---
N
L
P
L
Q
L
G
F
S
T
G
------
V
N
L
V
A
V
P
T
G
Y
V
D
T
E
N
N
T
E
F
-----
T
R
V
N
A
K
P
P
PGDQF
K
H
L
I
P
L
M
Y
KGLP
W
N
V
V
R
I
K
I
------
V
Q
M
L
S
D
T
L
K
G
L
S
D
R
V
V
F
V
L
W
A
H
G
F
E
L
-
T
S
M
K
---
Y
F
V
K
I
G
P
E
RTC
C
L
C
D
K
R
A
T
C
F
-
S
T
S
S
D
T
Y
A
C
W
N
H
S
V
G
F
D
Y
V
Y
N
P
--------------------
F
M
I
D
V
Q
Q
W
G
F
T
G
N
L
Q
S
N
H
D
Q
H
----
C
Q
V
H
G
N
A
H
V
----------------
A
S
C
D
A
I
M
T
R
C
-
L
A
V
H
E
C
F
V
K
R
V
D
W
S
V
E
Y
P
I
I
G
D
E
L
R
V
N
S
A
C
R
K
-----
V
Q
H
M
V
V
K
-
S
A
L
L
A
D
K
-------
F
P
V
L
H
--
D
I
G
N
-
P
K
A
---
I
K
----
C
V
---
P
Q
A
E
-
V
E
---
W
---
K
F
Y
D
A
---
Q
----
P
-
C
S
D
--------------------------
K
A
Y
K
I
E
E
L
--
F
Y
S
Y
A
T
H
H
D
-
K
----
F
T
D
G
V
C
L
F
------
W
N
C
N
V
D
------
R
Y
---
P
A
N
-
A
I
V
C
R
-
F
D
-
T
R
V
L
S
N
--
L
-
N
L
P
G
---
C
DG
G
S
L
Y
V
N
K
H
A
F
H
T
P
A
F
D
K
S
A
F
-
T
N
L
K
Q
L
P
F
F
Y
Y
S
DSPCEY
V
P
L
K
S
A
T
C
--
I
T
R
C
N
L
-
G
G
A
V
C
R
H
H
A
N
E
Y
R
Q
Y
L
D
A
Y
N
M
M
I
S
A
G
F
S
L
W
I
YKQFD
T
Y
N
L
W
N
T
F
TR
15
Fugue
79.33
20%
-55
* C10 *
4CI2
2
CRBN_CHICK
B:
[71-451]
----------------------------------------
M
I
N
F
D
T
S
L
P
T
S
H
M
Y
L
G
S
D
M
E
E
F
H
---
G
R
T
L
H
D
---------------
D
D
S
C
Q
V
I
P
V
-------
L
P
H
V
-----------------
M
V
----
M
-------
L
I
P
G
------------------
Q
T
L
P
L
Q
L
F
H
P
Q
E
V
S
M
V
R
N
L
I
Q
K
D
R
-
T
------
F
A
V
L
A
Y
S
N
V
R
--------
E
-----
R
------------
E
A
H
F
G
T
T
A
---------
E
I
Y
------
A
Y
R
E
E
Q
E
Y
G
-
I
E
T
V
K
V
K
A
I
G
R
Q
R
F
K
V
-
L
E
I
R
T
Q
S
D
----------
G
I
-
Q
Q
A
K
V
Q
I
--------------
L
P
E
R
V
L
--
P
--------------------
S
T
M
---
S
A
V
Q
L
Q
S
L
S
R
R
H
I
R
A
----
F
R
Q
W
W
Q
K
Y
Q
---
K
---
R
K
-------------
F
H
C
A
-
S
L
T
S
W
P
P
W
L
Y
S
L
Y
D
------
A
E
T
L
M
E
R
V
K
R
Q
L
-----
H
E
W
------
D
E
N
L
K
D
E
------
S
L
P
T
N
P
I
D
F
S
Y
-
R
V
A
A
C
L
P
I
----
D
D
---
A
L
R
I
-
Q
L
---
L
K
IG
S
A
I
Q
R
---
L
R
C
E
L
D
-
I
M
N
--------------------------
K
C
T
S
L
C
C
K
--
Q
C
Q
D
T
---------------
E
I
T
------
T
K
N
E
I
F
S
L
S
L
C
G
-----
P
M
A
-
A
Y
V
N
P
-
H
G
Y
I
H
E
T
L
T
--
V
Y
K
A
C
N
---
L
--
N
L
S
G
R
P
S
T
E
H
S
W
F
P
G
Y
A
W
T
I
-
A
Q
C
R
I
-----------------
C
G
N
H
M
G
W
K
F
T
A
T
-
K
K
D
M
S
---
P
Q
K
F
W
G
L
T
R
S
A
L
L
P
R
-----------------------
18
Fugue
77.96
19%
-35
- C10 -
4ZOX
-
SQT1_YEAST
A:
[3-381]
----------------------------------------
M
S
N
N
S
-----------
L
T
Y
F
D
K
H
---
T
D
S
V
F
A
-------------
I
G
H
H
P
N
L
P
L
V
C
T
G
G
G
D
N
L
A
H
L
W
-----------------
T
S
HSQP
P
-------
K
F
A
G
T
L
T
GYG
E
--
S
V
I
S
C
S
F
T
S
E
G
-
G
F
L
V
T
A
D
-------------
M
S
G
------
K
V
L
V
H
M
G
Q
K
G
G
A
Q
W
K
L
A
S
Q
-----
M
------------
Q
E
V
E
E
I
V
W
---------
L
K
T
-------
H
P
T
I
A
R
T
F
A
F
G
A
T
D
----
G
S
V
W
C
Y
Q
-
I
N
E
Q
---
D
----------
G
S
L
E
Q
L
M
S
G
F
---
V
H
Q
Q
D
C
S
M
G
E
F
I
N
T
D
K
G
--
E
--------------------
N
T
L
E
L
V
T
C
S
L
D
S
T
-----
I
V
A
----
W
N
C
F
T
G
Q
Q
L
---
F
---
K
I
T
Q
A
E
I
K
G
L
E
--
A
P
W
I
S
L
-
S
L
A
P
--
E
T
L
T
K
G
N
S
G
V
V
A
C
G
S
N
---
N
G
L
L
A
V
I
N
CNNG
G
A
I
L
H
L
S
T
V
I
E
L
K
P
E
Q
------------
D
E
L
D
A
-
S
I
E
---
S
I
----
S
W
---
S
S
K
F
S
L
M
---
A
---
I
G
L
V
C
---
G
E
I
L
L
Y
-
D
T
S
--------------------------
A
W
R
V
R
H
K
F
--
V
L
E
D
------
S
----
V
T
--
K
L
M
F
------
D
N
D
D
L
F
A
S
C
I
N
G
K
V
---
Y
Q
F
N
A
R
T
G
Q
-
E
K
F
V
C
V
G
H
N
--
M
-
G
V
L
D
---
F
--
I
L
L
H
-
P
V
A
----------------
N
T
-----------------
G
T
E
Q
--
K
R
K
V
I
T
-
A
G
D
---------
E
G
V
S
L
V
F
E
V
P
N
-----------------------
19
Fugue
77.00
16%
-36
* C8 *
1QUV
-
?
A:
[1-556]
SMS
Y
T
W
T
GALITPCAAEESKLPIN
A
L
S
N
S
L
LRHHNM
V
Y
A
T
T
S
R
S
A
G
L
R
Q
K
K
V
T
F
D
R
L
Q
V
L
D
D
H
---
Y
R
D
V
L
K
-------------
E
M
K
A
K
A
S
T
V
K
A
K
L
L
S
V
E
E
A
C
K
L
TPPHSAKSKFGYG
A
K
D
V
R
N
----
L
-------
S
S
K
A
V
N
----
H
--
I
H
S
V
W
K
D
L
L
E
D
T
V
T
P
I
D
T
T
I
M
A
K
N
E
V
F
C
V
Q
P
E
K
G
G
R
K
P
A
R
L
I
V
F
P
D
L
G
V
-
R
V
C
E
K
M
A
L
Y
D
V
V
S
T
L
P
------------
Q
V
V
M
G
S
S
Y
---------
G
F
Q
YS
P
G
Q
R
V
E
F
L
V
N
T
W
K
S
K
K
N
P
M
G
F
S
Y
D
T
R
C
F
D
S
T
V
T
E
N
---
D
----------
I
R
V
E
E
S
I
Y
Q
C
-
C
D
L
A
P
E
A
R
Q
A
I
K
S
L
T
E
R
L
Y
--
I
G
G
P
L
T
N
SKGQNCGYRRCRAS
G
V
L
T
T
S
C
G
N
T
L
T
C
Y
L
K
A
S
A
A
C
R
AAK
L
Q
D
C
T
M
L
V
N
---
G
D
D
L
V
V
I
C
E
S
A
G
T
Q
E
D
A
A
S
L
R
V
F
T
E
A
M
T
R
Y
S
A
P
P
G
D
-----
P
P
Q
P
E
Y
D
L
E
L
I
T
S
C
S
-----
S
N
V
S
V
A
H
-
D
A
S
G
K
R
V
Y
------
Y
L
T
R
D
P
T
T
P
L
A
-
R
A
A
---
W
E
----
T
A
R
HT
P
V
N
S
-
W
L
---
G
---
N
I
I
M
Y
APT
L
W
A
R
M
I
-
L
M
T
--------------------------
H
F
F
S
I
L
L
A
Q
E
Q
L
E
K
A
L
D
C
Q
I
Y
----
G
A
--
C
Y
S
I
------
E
P
L
D
L
P
Q
I
I
E
R
L
H
G
---
L
S
A
-
F
S
L
H
S
Y
S
P
G
E
I
N
R
V
A
--
S
-
C
L
R
K
---
L
--
G
V
P
P
L
R
V
W
R
H
R
A
R
S
V
R
A
R
L
L
-
S
Q
G
G
R
-----------------
A
A
T
C
--
G
K
Y
L
F
N
-
W
A
V
K
T
K
L
K
L
T
P
I
P
A
A
S
L
S
G
W
F
V
A
G
YS--------------------
23
Fugue
66.17
17%
-17
- C8 -
4WMY
5
ITLN1_HUMAN
A:
[24-306]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
S
S
S
P
S
L
P
R
S
C
K
E
I
K
D
E
C
P
S
A
F
D
G
------
L
Y
F
L
R
T
E
N
G
V
--
I
Y
Q
T
F
C
D
-----
M
------------
T
S
G
G
G
G
-----------
W
T
L
------
V
A
S
V
H
E
N
D
M
R
G
K
C
T
V
G
D
R
W
S
S
Q
Q
G
S
K
-
A
V
Y
P
---
E
----------
G
D
G
N
W
A
N
-----
Y
N
T
F
G
S
A
E
A
A
T
S
--
D
D
Y
K
--
N
--------------------
P
G
Y
Y
D
I
Q
A
K
D
L
G
I
W
H
V
P
N
K
S
P
----
M
Q
H
W
R
N
S
-----
S
---
L
L
R
Y
R
T
D
T
G
F
L
Q
T
L
G
H
N
L
F
-
G
I
Y
Q
K
Y
P
V
K
Y
G
E
G
K
C
W
T
D
N
G
P
V
I
P
V
--------------
V
Y
D
F
G
-
D
A
Q
K
T
A
S
Y
------
Y
S
P
Y
G
Q
R
E
F
T
A
-
G
F
V
---
Q
F
----
R
V
---
F
N
N
E
-
R
A
---
A
---
N
A
L
C
A
---
G
M
R
V
T
G
C
N
T
E
HHC
I
G
G
G
GYFPEASPQQCGDFSGFDW
S
G
Y
G
T
H
V
G
--
Y
S
S
S
R
E
I
T
E
------
A
A
--
V
L
L
F
------
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
62.11
13%
-11
- C7 -
3IYM
-
?
A:
[39-434]
----------------------------------------
A
S
A
S
K
A
A
A
F
A
Q
G
G
S
S
D
P
V
--
P
M
P
---
G
K
Y
P
V
V
-------------
F
S
T
G
A
G
E
P
T
R
D
Q
E
F
A
L
P
V
H
K
A
F
-----------------
P
L
----
F
GSVSDKY
R
R
N
P
R
Y
----
A
--
E
F
R
A
H
S
E
F
T
D
G
---
V
F
G
T
H
L
A
V
S
S
L
L
R
L
A
Q
Q
L
V
H
A
------
H
V
N
M
G
L
P
L
G
D
F
A
P
L
A
S
S
D
------------------------------------
V
R
I
------
P
S
A
L
A
S
V
V
N
Q
F
G
E
F
S
S
P
S
I
G
T
---
R
F
-
L
L
R
D
---
F
----------
E
H
A
V
S
R
V
V
F
L
-
A
D
Q
L
W
T
N
G
N
S
H
H
I
F
A
R
S
W
L
--
P
--------------------
M
S
N
N
D
G
N
F
K
T
I
V
--
A
S
R
L
L
E
F
----
I
S
A
G
D
L
S
I
L
---
P
---
T
V
L
E
D
A
V
L
S
G
E
V
P
E
A
W
E
Q
V
-
K
D
L
L
G
D
A
P
G
V
G
------
Q
V
D
R
R
D
R
F
D
F
L
F
K
S
Y
-----
A
D
V
G
Q
F
T
-
T
A
F
T
T
Q
A
A
------
S
D
V
L
T
E
L
G
L
P
W
N
S
P
S
---
A
G
----
H
L
---
N
W
Q
Y
-
S
T
---
K
---
Q
R
F
T
F
---
L
A
D
T
W
A
-
K
L
S
--------------------------
A
A
Y
S
Q
F
F
E
--
L
S
S
G
L
A
T
R
Q
-
S
----
A
T
--------------------
G
S
H
A
Q
M
---
V
D
L
-
T
S
V
E
G
-
V
T
V
L
K
A
A
L
A
--
L
-
S
A
P
E
---
F
--
S
L
--
A
A
C
F
P
P
S
C
I
F
V
G
------
G
L
T
R
-----------------
R
V
V
V
--
T
T
S
L
S
V
-
S
Q
R
A
T
E
F
C
Q
M
D
W
R
---------------------------------
3
PsiBlast_PDB
50.78
24%
-26
* C11 *
3HHE
3
RPIA_BARHE
A:
[125-225]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
K
I
V
A
-
S
A
S
---
R
A
----
M
F
---
V
I
A
D
-
E
T
---
K
---
M
V
K
T
L
---
G
A
F
A
L
P
-
I
E
V
--------------------------
N
P
F
G
I
H
A
T
--
R
I
A
I
E
K
A
A
D
-
N
L
G
L
S
G
E
--
I
T
L
R
------
M
N
G
D
D
P
F
K
T
D
G
G
H
F
---
I
F
D
-
A
F
W
G
R
-
I
L
Q
P
K
L
L
S
E
A
L
L
-
A
I
P
G
---
V
--
V
E
H
G
L
F
L
G
L
A
S
R
A
I
V
A
M
A
D
S
-
Q
I
K
V
L
-----------------
E
P
F
D
--
F
----------------------------------------------------
1
PsiBlast_PDB
44.93
35%
45
* C12 *
1H45
2
TRFL_HUMAN
A:
[179-233]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
K
C
A
F
S
S
Q
E
P
Y
F
S
Y
S
G
A
F
K
C
-
L
--
R
---
D
----------
G
A
G
D
V
A
F
I
G
E
-
S
T
V
F
E
D
L
S
D
E
A
E
R
D
E
Y
E
L
L
--
C
--------------------
P
D
N
T
R
K
P
V
D
K
F
K
D
C
H
L
A
R
V
P
S
----
H
A
V
V
A
R
S
V
N
---
G
---
K
E
D
A
I
W
N
L
L
R
Q
A
Q
E
K
F
G
K
D
-
K
S
P
K
F
Q
L
F
G
S
P
S
G
Q
K
D
L
L
F
K
D
S
A
I
G
F
S
R
V
P
P
R
-----
I
D
S
G
L
Y
L
-
G
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
37.67
21%
226
- C9 -
3J40
-
?
N:
[24-62]
----------------------------------------------------------------------------------------------
D
Q
Y
P
W
G
L
-
R
I
T
L
D
-----------------
N
E
----
S
-------
L
Q
R
--
L
----
G
--
L
N
A
-
K
S
L
P
A
V
G
D
S
V
S
V
M
A
M
A
N
V
C
S
V
S
T
R
T
T
D
H
G
E
D
------
N
Y
V
E
L
Q
I
T
D
I
G
L
A
P
Q
K
R
D
D
-----
A
------------
K
E
L
K
D
A
F
Y
---------
P
D
G
------
E
D
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.64
28%
86
* C13 *
1WA9
-
PER_DROME
A:
[280-346]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
-
R
----
A
T
--
F
A
S
Q
------
I
T
T
G
I
----------------
A
K
S
T
F
-
C
V
M
L
R
R
Y
R
G
--
L
-
K
S
G
G
---
F
--
G
V
I
G
R
P
V
S
Y
E
--
P
F
R
L
G
L
T
F
-
R
E
-------------------------------------------------------------------------------
12
HHSearch
34.61
10%
117
* C9 *
3D12
1
EFNB3_MOUSE
B:
[88-129]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
Q
E
Y
S
P
N
L
W
G
H
E
F
R
S
H
H
D
Y
-
Y
I
I
A
T
-----------------
S
D
G
T
--
R
E
G
L
E
S
L
Q
G
G
V
C
L
T
R
G
M
K
V
L
L
R
V
G
Q
----------------------------
4
PsiBlast_PDB
32.01
39%
10
- C11 -
4ZDN
-
?
A:
[207-239]
----------------------------------------------------
L
Y
L
H
P
S
S
Y
V
E
L
---
C
R
S
R
M
L
-------------
A
T
D
G
H
C
R
S
F
G
A
G
G
D
G
F
L
P
G
E
G
V
-----------------
G
A
----
V
-------
L
L
K
P
L
S
----
A
--
A
E
A
D
G
D
P
I
H
A
V
I
V
G
S
A
I
N
H
G
G
R
T
N
G
Y
T
V
P
N
P
R
A
Q
A
------
A
L
I
R
D
A
L
D
R
A
G
V
S
A
A
G
I
G
Y
-----
I
------------
E
A
H
G
T
G
T
R
---------
L
G
D
------
P
V
E
I
D
G
L
T
Q
A
F
A
P
D
G
A
C
A
L
G
S
V
K
S
N
I
-
G
H
L
E
---
A
----------
A
A
G
I
A
G
L
T
K
A
-
V
L
Q
L
Q
H
G
E
F
A
P
T
L
H
A
E
Q
T
N
--
P
--------------------
D
I
D
F
A
A
T
P
F
T
L
Q
T
G
G
A
P
W
P
R
P
----
A
D
G
G
P
R
R
A
G
---
I
---
S
S
F
G
A
G
G
A
N
A
H
V
I
V
A
E
Y
R
S
-
A
T
P
A
P
A
T
P
A
P
S
A
R
P
V
L
L
P
L
S
A
R
T
T
E
D
L
H
A
R
A
G
-----
Q
L
S
D
L
L
R
-
N
G
A
P
V
D
L
P
------
A
V
A
A
T
L
Q
T
G
R
E
-
E
M
A
---
E
R
----
V
C
---
F
V
A
S
-
T
P
---
G
---
E
W
L
D
Q
---
L
G
A
F
L
A
-
D
E
V
--------------------------
P
W
S
R
G
R
V
R
--
A
T
R
E
T
L
A
A
L
-
A
----
E
K
--
D
E
L
R
------
A
L
V
T
R
W
I
N
R
G
D
W
H
D
---
L
A
A
-
F
W
A
K
G
-
M
P
L
D
W
T
R
L
H
--
T
-
P
A
R
V
---
H
--
L
P
A
Y
P
F
A
G
R
Q
F
W
F
G
P
---------------------------------------------------------------------------------------
11
HHSearch
31.09
18%
701
- C3 -
2GPV
-
NCOR2_HUMAN
G:
[5-15]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
A
I
I
R
--
K
-
A
L
M
G
------------------------------------------------------------------------------------------------------------
9
HHSearch
30.88
15%
208
- C4 -
2PNL
1
POLS_IPNVS
A:
[90-115]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
C
Y
T
A
L
P
L
-
K
E
I
K
--
R
-
N
G
N
I
V
V
E
K
I
F
A
--
G
--------------------
P
I
M
G
P
S
A
Q
L
G
L
S
L
L
V
N
D
I
E
D
G
----
V
P
R
M
V
F
T
G
E
---
I
---
A
D
D
E
E
T
I
I
P
I
C
G
V
D
I
A
A
I
A
-
A
H
E
Q
G
L
P
L
I
G
N
Q
P
G
V
D
E
E
V
R
N
T
S
L
A
A
H
L
I
Q
T
G
-----
T
L
P
V
Q
R
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
30.06
39%
402
- C13 -
2FVH
-
URE3_MYCTU
A:
[76-93]
----------------------------------------------------------------------------------------------------------------------------------------------
M
L
----
A
--
E
V
Q
V
E
A
T
F
P
D
G
T
K
L
V
T
V
H
Q
P
I
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
29.56
4%
229
- C11 -
1LYP
-
A:
[2-26]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
R
L
R
K
F
R
N
K
----
I
K
E
K
L
K
K
I
G
---
Q
---
K
I
Q
G
L
L
P
K
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
27.92
25%
682
- C1 -
2OVM
1
?
B:
[13-23]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
D
I
I
R
--
K
-
A
L
M
G
------------------------------------------------------------------------------------------------------------
8
HHSearch
24.84
15%
403
- C12 -
2XPN
-
?
B:
[3-21]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
F
-
F
E
I
F
G
-----------------
T
G
E
E
--
Y
R
Y
V
L
E
-
S
---------------------------------------------
6
HHSearch
19.08
36%
613
- C11 -
2JSH
-
A:
[7-20]
--------------------------------------------------
V
G
I
K
L
S
G
A
Q
Y
Q
Q
H
---
G
R
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------