@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0088: (2015-12-21 )
MNPRLLEYYNQELQHIRESAAEFAEEFPKIAGRLSLSGFECADPYVERLLEGFAYLTARVQLKLDAEYPTFTHNLLEIAYPHYLAPTPSMTVVQLRPDPNEGALSSGFSIERGASLRGQLGPDDQTACEYRTAHPVTLWPLEVAQADYFGNPAAVLGRLAASEPRAKAGLRIRLRSGAGIPFDSLSLDALPLYLHGADEQPYRLYEQLLGNACAVFVRAPDNAWVERLPTSSLRARGFDDEDALLPVVPRAFQGYRLLQEYFALPARFLFVEFSGLNRALRRCHGEELELVVLFGKHDQRLEGTVDAEQLVPFCTPAINLFPRRCDRIHLSDRVNEHHVIVDRTRPLDFEVHSLQQVSGHGSGPEQPFQPFYAVRDPARYGREQAYFRVRREPRVLSSKQRRKGPRSTYVGSETFVALVDANQAPYRHDLRQLGIAALCTNRDLPLFMPIGAHKSDFTLEDSAPVMQVRCLAGPSRPRASRAHDASAWRLISQLSLNYLSLAERGQGAAALRELLRLYGDSGDPALQLQIEGLREVSSKPCTRRLPMPGPIVFGRGLEITLDFDENAFRGTGVFLLGAVFERFLARYVSINSFTETVLRTGERGEVMRWQAKPGSRPNL
Atome Classification :
(20 SA)
--------------------------.........--10.......-------.20...----.....30-.......-------------.40..----......50........60......----------------.-.70........80------........90.......--.100......--.110.......120...-....130-.........140....-...150.......160.......170.....-..180.....-..190......----.200....-...--210-.......220........230..-----.....240-----........-.250.-----------------..-----....260..---------.--------..-..270.......--280...-----..-..290------.....--------....300-.......310.......320.......--------------330......------.340.......350.......360.-......370...--....380..----------.....390....------...-400.......410..-.......420.........430---------.......440...-....450.------......460-......-...470.......480.......490----------.---...--...500..---.--....510.....---------..520.....-..530--......------.540----------.......-----------------------.550...-...----------.560--.....-----..570........580..-..---...590.----....--..600----..-------------......610.......--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------MN
P
R
L
L
E
Y
Y
--
N
Q
E
L
Q
H
I
R
E
-------
S
A
A
E
F
A
----
E
E
F
P
K
I
A
-
G
RLSLSG-------------FECA
D
----
P
Y
V
E
R
L
L
E
G
F
A
Y
L
T
A
R
V
Q
L
K
LDAE----------------Y-P
T
F
T
H
N
L
L
E
I
AYP------HYLAPTP
S
M
T
V
V
Q
LRPD--PNEGALSSGF--SIERGASLRGQLGPDDQ-TA
C
E
Y---RTAH
P
V
T
L
W
P
L
EVAQA-DYFG
N
P
A
A
V
L
G
R
L
AASEPRAKA
G
L
R
I
R
LRSG-AGIPFDSLSL-D
A
L
P
L
Y
L
HGAD----E
Q
P
Y
R
L
Y
E
-
Q
L
L--GN
A
-
C
A
V
F
V
RAP-
D
N
A
W
V
E
RLPT
S
S
LR-----ARGFDD-------EDAL
L
P
VV-
P
R
A
F
Q
-----------------
G
Y
-----
R
L
L
Q
E
Y
FAL---------P--------
A
R
-
F
L
F
V
E
FS
G
L
N
R
A
--
L
R
R
CHG-----EE-
L
E
L
--------
V
V
L
FG--------KHDQRLE-GTV
D
A
E
Q
L
V
P
FC
T
P
A
I
N
L
F
P
RRC
D
R
I
H
--------------
L
S
DRVNE
H
H
------
V
I
V
DRTRPL
D
F
E
V
H
S
L
Q
Q
V
SGHGSG-PEQPFQ
P
F
YAVR--
D
P
A
R
YG
R
E
Q
----------
A
Y
F
R
VRRE
P
R
V
L
------
S
S
K
-
Q
RRKGPRSTYV--GS-
E
T
F
V
A
L
VD--ANQA
P
Y
R
H
D
L
R
Q---------L
G
I
A
ALCTNRDL
P
-
L
F
M
P
IGAH------KSDFTLE---DSA
P
V
M
-
Q
V
R
CLAGPSRPRASRAH
D
A
S
A
W
R
L
I
S
----------
Q
---
L
S
L
--
N
Y
L
S
L
A
E
R---G--Q
G
A
A
A
L
R
E
L
L
R
L
---------YGDSGD
P
A
L
Q
-
L
Q
I
E
G
--
L
R
E
V
SS------KPC-----------TRRLPMP-----------------------G
P
I
V
FGR-G
L
E
----------
I
T
L
D--FDENA-----FRG
T
-
G
V
F
L
L
G
A
V
F
E
R
F
L
-
A
R
---
Y
V
S
I
N
S
F
----
T
E
T
V
--
L
RTG-----ER-------------G
E
V
M
R
W
QAKPGSRPNL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
83.27
20%
-51
- C4 -
4MR0
7
PFBA_STRR6
A:
[114-571]
---------------------------
T
A
L
S
V
K
D
Y
--
G
A
V
G
D
G
I
H
D
-------
D
R
Q
A
I
Q
----
D
A
I
D
A
A
A
-
Q
G
L
G
G
G
N
-------------
V
Y
F
------
P
E
G
T
Y
L
V
K
E
I
V
F
L
K
S
H
T
H
L
E
L
N
-
E
----------------
K
-
A
T
I
L
N
G
I
N
I
K
N
H
P
------
S
I
V
F
M
T
G
L
F
T
D
D
G
A
Q
V
E
W
G
P
T
E
D
I
S
Y
S
G
G
--
T
I
D
----
M
N
G
A
L
N
E
E
G
T
-
K
A
-----------
K
N
L
P
L
I
N
S
S
G
A
-
F
A
I
G
N
-----------------
S
N
N
V
T
I
K
----
N
V
T
F
K
D
-
S
Y
-
Q
G
H
A
I
Q
I
A
G
S
------
K
N
V
L
V
D
N
S
R
F
L
--
G
Q
A
-
L
P
K
T
M
K
D
G
-
Q
I
I
S
K
E
S
I
Q
I
E
P
L
T
-----
R
K
G
F
P
Y
---------
A
L
N
D
D
G
-
K
K
S
-
E
-----------------
N
V
-----
T
I
Q
N
S
Y
F
G
K
---------
S
--------
D
K
-------
S
G
---------------------
E
L
--------
V
T
A
I
G
--------
T
H
Y
Q
T
L
S
-
T
Q
N
---------
P
S
N
I
K
I
L
N
N
H
F
D
----------------------
N
M
M
Y
------
A
G
V
R
F
T
G
F
T
D
V
L
I
K
G
N
----------------------------------------------
R
F
D
K
K
V
K
G
E
------
S
V
H
-
Y
R
E
S
G
--------------
A
A
L
V
N
--
A
Y
S
Y
K
N
T
K
D
L
----------------------
L
D
-
L
N
K
Q
V
V
I
A
------
E
N
I
F
N
I
A
---
D
--
P
K
T
-
K
A
I
R
V
A
K
D
S
A
E
Y
L
G
K
V
S
D
----
I
T
V
T
----------
K
---
N
V
I
--
N
N
N
S
--------------------------------
K
E
T
E
Q
P
N
I
E
-
L
L
------------------
R
V
-----------
S
D
N
L
V
V
S
-----------------------
E
N
S
I
F
G
G
-
K
E
G
----------
I
V
I
E
--
D
S
K
G
K
-----------
I
T
V
L
N
N
Q
F
Y
N
L
S
-
G
K
---
Y
I
S
F
I
K
S
N
A
N
G
K
E
P
V
--
I
S
D
G
N
F
N
I
V
T
E
-------------
N
G
L
Y
K
I
V
T
N
N
L
S
D
K
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
69.12
16%
-31
- C6 -
3K9D
1
?
A:
[3-456]
-----------------------LED
K
D
L
R
S
I
Q
E
V
--
R
N
L
I
E
S
A
N
K
-------
A
Q
K
E
L
A
A
MS
Q
Q
Q
I
D
T
I
V
-
K
A
I
A
D
A
G
-------------
Y
G
A
R
E
----
K
L
A
K
M
A
H
E
E
T
G
F
G
I
W
Q
D
K
V
I
K
N
V
F
----------------
A
-
S
K
H
V
Y
N
Y
I
K
----------------
D
M
K
T
I
G
M
L
K
E
D
--
N
E
K
K
---------------
V
M
E
V
A
V
P
L
G
V
-
V
A
G
L
I
---
P
S
T
N
P
T
S
T
V
I
Y
K
T
L
I
S
-
I
K
A
G
N
S
I
V
F
S
P
H
P
N
A
L
K
A
I
L
E
T
V
R
I
I
S
E
A
A
E
K
A
G
C
P
K
G
A
I
S
C
----------
M
T
----
V
P
T
I
Q
G
T
D
-
Q
L
M
--
K
H
K
D
T
A
V
I
L
A
T
G
-
G
S
A
M
V
K
A
A
Y
S
S
G
T
P
-----
A
I
G
V
G
P
-------
G
N
G
-----------------------------------------------------------------
P
A
F
I
E
----------
R
S
A
N
I
-----
P
R
-
A
V
K
--------
H
I
L
D
S
--------
K
T
F
D
N
---
G
T
I
C
A
-----------------------------------------
S
E
Q
S
------
V
V
V
E
R
V
N
K
E
A
V
I
A
E
F
R
K
Q
------------------------------
G
----------
A
H
F
L
S
D
A
E
A
V
Q
L
------
G
K
F
I
L
R
P
N
G
S
M
N
P
A
I
--
V
G
-
K
S
V
Q
H
I
A
N
--
L
-------------------------------------------------
A
G
L
T
V
P
---
A
D
A
R
V
L
-
I
A
E
E
T
K
V
G
A
K
I
P
Y
S
R
E
K
L
A
P
---------------------
I
L
--
A
F
Y
T
A
E
T
W
---
Q
--
E
A
C
E
L
S
M
D
I
L
Y
H
---------
E
G
A
G
H
T
L
I
I
H
S
E
D
K
E
I
--
I
R
E
F
A
L
------
K
K
P
-----------
V
S
R
L
L
V
N
-----------------------
T
P
G
A
L
G
G
I
G
-------------------
A
T
T
N
-----
L
V
P
A
-
L
T
L
G
C
G
A
V
G
G
S
S
S
-
S
D
---
N
I
G
P
E
N
L
----
F
N
I
R
--
R
I
A
T
-----
G
V
-------------
L
E
L
E
D
I
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
68.03
16%
-38
- C5 -
3WAI
-
MALE_ECOLI
A:
[3-739]
-----------------------G
M
K
I
E
E
G
K
L
V
I
W
--
I
N
G
-
D
K
G
Y
N
-------
G
L
A
E
V
G
----
K
K
F
E
K
D
T
-
G
----------------------------------------------
I
K
V
T
V
E
----------------
H
-
P
----
D
K
L
E
E
K
F
P
------
Q
V
A
A
T
G
D
G
P
D
I
I
F
W
A
H
D
--
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
K
A
F
Q
D
K
L
Y
P
F
T
W
-
D
A
V
R
Y
NGK
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
P
N
P
P
K
T
W
E
E
I
P
A
L
D
K
E
L
K
A
K
G
K
S
A
L
M
F
N
-
L
Q
E
P
Y
F
T
W
P
L
-
I
A
A
D
---
G
G
Y
A
----
F
K
D
V
G
V
D
N
-
A
G
A
--
K
A
G
-
L
T
F
L
V
D
L
I
-
K
N
K
H
M
N
A
D
T
D
Y
S
I
A
-----
E
A
A
F
N
K
-------
G
E
T
A
M
T
I
N
G
P
W
A
W
S
-----------------
N
I
-----
D
T
S
K
V
N
Y
G
V
T
V
L
P
T
F
KG
Q
P
--------
S
K
P
F
V
G
V
L
S
A
G
I
N
A
A
SP
N
K
E
L
A
K
-----
E
F
-
L
E
N
--------
Y
L
L
T
-----------
D
E
G
L
E
-
A
V
N
K
D
K
P
L
G
A
V
A
L
K
S
Y
E
E
E
L
A
K
D
P
R
I
A
--------------
A
T
M
E
N
A
Q
K
G
------
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
-
G
R
Q
T
V
D
E
A
L
K
D
A
--
Q
T
N
K
Q
W
Y
D
A
----------
L
T
W
M
R
E
N
T
P
D
---------
G
E
-
K
Y
D
E
Y
P
F
E
T
Y
G
V
I
S
W
-
W
D
Y
G
H
W
I
E
A
V
A
H
R
M
P
I
A
N
P
F
Q
A
GIGNKYNNV
P
G
A
S
S
F
F
T
A
E
N
E
S
-
Y
A
E
F
V
A
E
K
L
NVK
Y
V
V
S
D
I
E
M
E
----
T
G
K
Y
Y
-
A
M
A
V
W
A
E
G
D
L
P
L
A
E
K
Y
Y
G
G
Y
F
Y
Y
S
P
T
G
T
F
G
Y
A
NSQW
D
---
I
P
L
--
N
S
I
I
I
P
L
R
I
P
S
E
--
L
Y
Y
S
T
M
E
A
K
L
H
L
---------
F
D
G
S
G
L
S
H
Y
R
-
M
I
Y
E
S
DY
P
A
E
W
K
S
------
Y
S
S
-----------
Q
V
N
L
N
N
E
-----------------------
S
Q
V
L
Q
T
A
-
L
Y
E
----------
A
V
M
R
A
R
Y
G
V
S
P
-----
T
M
G
T
-
Q
E
V
L
Y
K
Y
A
Y
T
Q
L
Y
-
E
K
---
K
M
G
I
P
V
K
----
I
A
P
S
GY
V
K
I
F
-----
E
R
-------------
V
K
G
A
V
V
T
G
K
V
S
A
N
V
T
E
V
S
V
N
A
T
I
K
T
NQN
R
T
F
E
Y
W
Q
T
V
E
V
K
NG
T
Y
T
V
V
L
PYSHNSDYPVKPIT
P
Y
H
I
K
AGN
V
V
K
E
I
T
I
Y
E
S
Q
V
Q
N
G
E
I
I
Q
L
D
L----------------------------------------------------------------------------------------------
29
Fugue
66.20
17%
-39
* C6 *
4PKF
4
?
A:
[8-864]
K
V
L
E
Y
KG
K
K
L
N
FTPEDPAEETIPADE
L
H
E
H
L
Q
K
P
S
--
T
A
R
T
K
R
L
K
E
R
CRWKHA
S
A
G
E
F
I
----
E
K
S
V
T
A
G
I
E
R
M
R
Y
L
T
-------------
E
A
H
K
A
S
EGK
P
E
A
I
R
R
A
L
G
L
A
N
V
L
N
K
S
T
L
V
L
Q
E
D
EFIVGYHAEDPN
M
F
P
L
Y
-
P
E
L
S
H
M
A
V
Q
D
Y
L
R
------
S
D
Y
S
P
Q
P
A
D
E
A
A
A
I
N
E
Y
--
W
K
P
H
S
L
Q
S
K
C
--
Q
P
Y
F
D
P
A
D
L
G
R
M
Y
Q
V
S
S
M
E
A
P
S
F
---
A
S
G
Y
N
S
I
V
P
P
Y
E
T
V
L
E
-
D
G
L
L
A
R
I
K
L
A
E
K
H
I
A
E
A
Q
A
D
M
S
T
F
P
W
N
G
T
K
G
-
L
D
N
I
A
K
I
D
N
W
-
K
A
M
V
I
A
C
K
A
V
I
----
S
W
A
R
R
Q
G
R
-
L
C
K
--
I
V
A
-
E
N
F
E
T
D
P
K
-
R
Q
A
E
L
L
E
I
A
D
I
C
Q
R
IPAEP
C
K
G
L
K
D
A
M
Q
A
K
F
F
T
F
L
I
C
H
A
I
-
E
R
Y
A
S
-----------------
G
Y
AQK
E
D
T
L
L
W
P
Y
Y
K
A
S
VVDKKFQP
M
--------
S
H
-
M
D
A
V
E
L
V
E
M
E
R
L
--
K
I
S
E
H
G
AGKS
R
A
Y
-
R
E
I
F
PGSN
D
L
F
I
L
T
V
G
GTNAKGED
A
C
N
D
M
T
D
-
A
I
L
E
A
A
K
R
I
R
T
A
E
P
S
I
V
F
R
Y
S
K
K
N
R
E
K
--------------
T
L
R
W
V
F
E
C
I
R
D
GLGY
P
S
I
K
H
D
E
I
G
T
E
Q
M
K
E
Y
A
K
F
S
L
N
G
N
G
A
T
D
E
E
A
H
N
W
V
N
V
L
C
M
S
P
G
I
H
G
R
R
K
TQKTRSE
G
G
G
S
I
F
P
A
K
L
L
E
I
S
L
N
D
GYDW
S
Y
A
-
D
M
Q
L
G
P
K
T
G
D
L
--
S
S
L
K
S
F
E
D
V
W
E
--
A
F
R
K
Q
Y
Q
Y
A
I
N
L
C
--------
I
S
T
K
D
V
S
R
Y
F
E
Q
R
F
L
Q
M
P
F
V
S
A
------
I
D
D
G
C
M
E
L
GM
D
A
C
A
L
S
E
Q
P
N
G
W
H
N
P
I
T
T
I
V
A
A
N
S
L
V
A
I
K
K
L
V
F
----------
E
EKK
Y
T
L
--
E
Q
L
S
Q
A
L
K
---
A
N
W
E
G
F
E
E
M
R
V
D
F
K
R
APKWGNDD
D
Y
A
D
G
I
I
T
R
F
Y
-
E
E
I
I
G
G
E
M
R
K
I
T
N
YSG
G
P
V
M
P
T
GQAVG
L
Y
M
E
V
G
S
R
T
G
P
T
P
DGRFGGEAADDGGISPYMGTDKK
G
P
T
A
V
L
R
-
S
V
S
K
VQKNQK
G
N
L
L
N
Q
R
--
L
S
V
P
I
-----
M
R
S
K
H
G
F
E
I
W
N
S
Y
I
K
T
W
H
-
D
L
NID
H
V
Q
F
N
V
V
----
S
T
D
E
--
M
R
A
A
-----
Q
R
EPEKHHD
L
I
V
R
V
S
G
Y
S
A
R
F
V
D
I
P
T
Y
G
Q
N
T
I
I
A
RQE
Q
D
F
S
A
S
D
L
E
F
L
NVEI-----------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
56.93
11%
-31
- C3 -
3THX
3
MSH2_HUMAN
A:
[12-930]
---------ES
A
A
E
V
G
F
V
R
F
F
Q
G
MPE
K
P
T
T
T
V
R
L
F
D
R
G
D
F
Y
T
A
H
G
E
-------
D
A
L
L
A
A
----
R
E
V
F
K
T
Q
-
G
V
I
K
Y
M
G
P
AGAKN
L
Q
S
V
V
L
S
K
M
N
F
E
----
S
F
V
K
D
L
L
L
V
R
Q
Y
---
R
V
E
V
Y
K
N
R
A
----------------
S
-
K
E
N
D
W
Y
L
A
Y
K
A
S
P
GNLSQF
E
D
I
L
F
I
G
V
V
G
V
K
M
S
A
V
D
--
G
Q
R
Q
V
G
V
G
Y
V
--
D
S
I
Q
R
K
L
G
L
C
E
F
P
D
N
D
Q
-
F
S
N
L
E
---
A
L
L
I
Q
I
G
P
K
E
C
V
L
P
G
G
-
E
T
A
G
D
M
G
K
L
R
Q
I
I
Q
R
G
G
I
L
I
T
E
R
K
K
A
D
F
S
T
K
-
D
I
Y
Q
D
L
N
R
L
L
-
K
G
K
K
G
E
Q
M
N
S
A
----
V
L
P
E
M
E
N
Q
-
V
A
V
--
S
S
L
-
S
A
V
I
K
F
L
E
-
L
L
S
D
D
S
N
F
G
Q
F
E
L
T
-----
T
F
D
F
S
Q
-------
Y
M
K
L
D
I
A
A
-
V
R
A
L
N
LFQQSLAALLNKCKT
P
Q
G
Q
-----
R
L
V
N
Q
W
I
K
Q
---------
P
LMD
K
N
R
I
E
E
R
-
L
N
L
V
E
A
F
V
E
D
A
E
--
L
R
Q
T
L
Q
-----
E
D
L
L
R
R
--------
F
P
D
L
N
--------
R
L
A
K
K
F
Q
R
Q
A
A
N
L
Q
D
C
Y
R
L
-
Y
Q
G
I
N
Q
L
P
N
V
I
Q
A
L
E
K
H
EGKHQKLLLAVF
V
T
P
L
T
D
L
R
S
------
D
F
S
K
F
Q
E
M
I
E
T
T
L
D
M
D
Q
V
E
N
H
E
F
L
V
-
K
P
S
F
D
P
N
L
S
E
L
R
--
E
I
M
N
D
L
E
K
K
----------
M
Q
S
T
L
I
S
A
A
R
D
L
------
G
L
D
-
P
G
K
Q
I
K
L
D
S
S
A
--
G
Y
-
Y
F
R
V
T
C
K
E
--
E
K
V
L
R
N
N
K
N
F
S
T
---------
V
D
I
------
Q
G
V
K
-
F
T
N
S
K
L
T
S
------
L
N
E
E
Y
T
K
---
N
K
T
E
Y
E
-
E
A
Q
D
A
I
V
K
E
I
V
N
I
S
S
G
Y
V
E
P
M
Q
T
L
N
D
----------
V
---
L
A
Q
L
D
A
V
V
S
F
A
H
V
---
S
--
N
G
A
P
V
P
Y
V
R
P
A
I
---------
L
E
K
G
Q
G
---
R
-
I
I
L
K
A
--
S
R
H
A
C
V
------
E
V
Q
-----------
I
A
F
I
P
N
D
-----------------------
V
Y
F
E
K
D
K
-
Q
M
F
----------
H
I
I
T
--
G
P
N
M
G
G
K
S
T
Y
I
R
Q
T
-
G
V
I
V
L
M
A
Q
I
G
C
F
V
P
C
E
---
S
A
E
V
S
I
V
----
D
C
I
L
--
A
R
V
G
S
T
F
M
A
E
M
-------------
L
E
T
A
S
I
L
R
S
A
T
K
D
S
L
I
I
I
D
ELGRGTS
T
Y
D
G
F
G
L
A
W
A
I
S
E
Y
I
A
TKIG
A
F
C
M
F
A
T
HFHELTA
L
A
N
Q
I
P
T
V
N
N
L
H
V
T
A
L
T
T
EE
T
L
T
M
LY
Q
V
K
K
G
VCDQSF
G
I
H
V
A
E
L
A
NFP
K
H
V
I
E
C
A
K
Q
K
A
L
E
L
EEFQYKC
Y
L
E
R
E
Q
G
E
K
I
I
Q
E
F
L
S
K
V
K
Q
MPFTEMS
E
E
N
I
T
I
K
L
K
Q
L
K
A
E
V
I
A
K
NN
S
F
V
N
E
I
I
S
R
I
10
PsiBlast_PDB
48.89
36%
-70
- C7 -
2YAP
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
L
V
L
T
E
--------
D
M
M
A
A
R
F
-
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
E
--------------
N
Q
G
D
M
D
H
P
F
------
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
V
-
V
N
L
K
A
G
E
V
A
L
L
V
--
P
L
R
E
K
G
R
T
V
----------
F
H
C
H
I
V
E
H
E
D
R
G
------
M
M
G
-
V
L
E
V
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
48.71
36%
-70
* C7 *
2YAR
5
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
V
L
T
E
D
--------
M
M
A
A
R
F
F
-
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
E
N
--------------
Q
G
D
M
D
H
P
F
H
------
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
V
V
-
N
L
K
A
G
E
V
A
L
L
V
P
--
L
R
E
K
G
R
T
V
F
----------
H
C
H
I
V
E
H
E
D
R
G
M
------
M
G
V
-
L
E
V
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.71
36%
-70
- C7 -
2YAM
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
V
L
T
E
D
--------
M
M
A
A
R
F
F
-
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
E
N
--------------
Q
G
D
M
D
H
P
F
H
------
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
V
V
-
N
L
K
A
G
E
V
A
L
L
V
P
--
L
R
E
K
G
R
T
V
F
----------
H
C
H
I
V
E
H
E
D
R
G
M
------
M
G
V
-
L
E
V
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
48.58
36%
-70
- C7 -
4AI7
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
-
V
V
N
L
K
A
G
E
V
A
L
L
--
V
P
L
R
E
K
G
R
T
----------
V
F
H
C
H
I
V
E
H
E
D
R
------
G
M
M
-
G
V
L
E
V
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
48.47
36%
-69
- C7 -
2YAQ
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
V
L
T
E
D
--------
M
M
A
A
R
F
F
-
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
E
N
--------------
Q
G
D
M
D
H
P
F
H
------
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
V
V
-
N
L
K
A
G
E
V
A
L
L
V
P
--
L
R
E
K
G
R
T
V
F
----------
H
C
H
I
V
E
H
E
D
R
G
M
------
M
G
V
-
L
E
V
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
48.32
36%
-68
- C7 -
2YAH
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
V
L
T
E
D
--------
M
M
A
A
R
F
F
-
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
E
N
--------------
Q
G
D
M
D
H
P
F
H
------
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
V
V
-
N
L
K
A
G
E
V
A
L
L
V
P
--
L
R
E
K
G
R
T
V
F
----------
H
C
H
I
V
E
H
E
D
R
G
M
------
M
G
V
-
L
E
V
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
48.24
36%
-70
- C7 -
2XVB
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
-
V
V
N
L
K
A
G
E
V
A
R
L
--
L
V
P
L
R
E
K
G
R
----------
T
V
F
H
C
H
I
V
E
H
E
D
------
R
G
M
-
M
G
V
L
E
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
48.05
36%
-72
- C7 -
2YAF
5
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
-
V
V
N
L
K
A
G
E
V
A
L
L
--
V
P
L
R
E
K
G
R
T
----------
V
F
H
C
H
I
V
E
H
E
D
R
------
G
M
M
-
G
V
L
E
V
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.00
36%
-68
- C7 -
2YAE
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
-
V
V
N
L
K
A
G
E
V
A
L
L
--
V
P
L
R
E
K
G
R
T
----------
V
F
H
C
H
I
V
E
H
E
D
R
------
G
M
M
-
G
V
L
E
V
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
47.98
36%
-68
- C7 -
2XU9
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
-
V
V
N
L
K
A
G
E
V
A
R
L
--
L
V
P
L
R
E
K
G
R
----------
T
V
F
H
C
H
I
V
E
H
E
D
------
R
G
M
-
M
G
V
L
E
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
47.96
36%
-70
- C7 -
2YAO
6
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
R
A
W
K
D
-
V
V
N
L
K
A
G
E
V
A
L
L
--
V
P
L
R
E
K
G
T
V
----------
F
H
C
H
I
V
E
H
E
D
R
G
------
M
M
G
-
V
L
E
V
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
47.71
36%
-67
- C7 -
2XUW
4
?
A:
[177-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
L
V
L
V
N
G
A
L
R
P
T
L
V
A
Q
K
A
T
L
R
L
R
L
L
N
A
-
S
N
A
R
Y
Y
R
L
A
L
-
Q
D
H
P
L
Y
L
I
A
A
D
GGFL
E
E
P
L
E
V
S
E
-
L
L
L
A
P
G
E
R
-
A
E
V
L
V
R
L
R
-
K
E
G
R
F
L
L
Q
A
L
P
Y
D
R
-----
G
A
M
G
M
M
-------
D
M
G
G
M
A
H
A
-
M
P
Q
G
P
-----------------
S
R
-----
P
E
T
L
L
Y
L
I
A
---------
P
--------
K
N
-
P
K
P
L
P
L
P
K
A
L
S
P
--
F
P
T
L
P
A
-----
P
V
-
V
T
R
--------
R
L
V
L
T
--------
E
D
M
M
A
A
R
-
F
F
I
N
G
Q
V
F
D
H
R
R
V
D
L
K
G
Q
A
Q
T
V
E
V
W
E
V
--------------
E
N
Q
G
D
M
D
H
P
------
F
H
L
H
V
H
P
F
Q
V
L
S
V
G
G
R
P
F
P
Y
A
W
K
D
V
-
V
N
L
K
A
G
E
V
A
R
L
L
--
V
P
L
R
E
K
G
R
T
----------
V
F
H
C
H
I
V
E
H
E
D
R
------
G
M
M
-
G
V
L
E
V
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
41.09
26%
-24
- C8 -
1SSQ
-
CYSE_HAEIN
A:
[7-72]
-----------------------------------------
Q
H
I
R
Q
-------
E
A
K
E
L
A
----
E
N
E
P
M
L
A
-
S
F
F
H
S
T
I
-------------
L
K
H
---------
Q
N
L
G
G
A
---
L
S
Y
L
L
A
N
K
L
A
N
P
-------------------
I
M
P
A
I
S
L
R
E
I
I
E
------
E
A
Y
Q
S
N
P
S
I
I
D
C
A
A
C
D
I
--
Q
A
V
R
H
R
D
P
A
V
--
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
-
S
Y
R
I
T
---
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
-
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
-
G
E
T
S
V
I
E
N
D
V
-
S
I
L
Q
G
V
T
L
G
G
T
----
G
K
E
S
G
D
R
H
-
P
K
V
--
R
E
G
-
V
M
I
G
A
G
A
K
-
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
-----
A
N
S
V
V
L
-------
N
P
V
P
E
Y
A
T
-
A
A
G
V
P
-----------------
A
R
-----
I
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
33.32
8%
30
- C8 -
1OR7
-
RSEA_ECOLI
C:
[3-63]
---------------------------
K
E
Q
L
S
A
L
M
--
D
G
E
T
L
D
S
E
-----------------------
L
L
-
N
E
L
A
-------------------
H
N
----
P
E
M
Q
K
T
W
E
S
Y
H
L
I
R
D
S
M
R
G
D
T
P
E
V
----------------
L
H
F
D
I
S
S
R
V
M
A
A
I
E
E
------
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
33.21
33%
12
- C7 -
3ZDS
1
HGD_PSEPK
A:
[13-75]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
-
F
G
N
E
F
A
S
E
A
L
P
G
A
L
P
V
G
Q
N
S
P
Q
----
K
A
P
Y
G
L
Y
A
-
E
L
L
--
S
G
T
-
A
F
T
M
A
R
S
E
L
R
R
T
W
L
Y
R
I
R
P
S
A
L
H
-----
P
R
F
E
R
L
-------
A
R
Q
P
L
G
G
P
-
L
G
G
I
N
-----------------
P
N
-----
R
L
R
W
S
P
Q
P
I
---------
P
--------
A
E
-
P
T
D
F
I
E
G
W
L
P
M
A
--
A
N
A
G
A
E
-----
K
P
-
A
G
V
--------
S
I
Y
I
Y
--------
R
A
N
R
S
M
E
-
R
V
F
F
N
A
D
G
E
L
L
L
V
P
E
Q
G
R
L
R
I
A
T
E
L
G
V
--------------
M
E
V
E
P
L
E
I
A
------
V
I
P
R
G
M
K
F
R
V
E
L
L
D
G
Q
A
R
G
Y
I
A
E
N
H
-
G
A
P
L
R
L
P
D
L
G
P
I
--
G
S
N
G
L
A
N
P
R
----------
D
F
L
T
P
V
A
H
Y
E
E
A
------
E
G
P
-
V
Q
L
V
Q
K
F
L
G
E
H
--
W
A
-
C
E
L
Q
H
S
P
L
--
D
V
V
A
W
H
G
S
N
V
P
Y
---------
K
Y
D
L
R
R
F
N
T
I
G
T
V
-
S
F
D
H
P
D
P
S
------
I
F
T
V
L
T
S
---
P
T
S
V
H
G
-
M
A
N
M
D
F
V
I
F
P
P
R
W
M
V
A
E
N
T
F
R
P
P
W
F
H
----------
R
---
N
L
M
--
N
E
F
M
G
L
I
N
---
G
--
A
Y
D
A
K
A
E
G
F
L
P
G
---------
G
A
S
L
H
G
V
M
S
A
-
H
G
P
D
A
--
E
T
C
E
K
A
------
I
A
A
-----------
D
L
A
P
H
K
I
-----------------------
D
N
T
M
A
F
M
-
F
E
T
----------
S
Q
V
L
--
R
P
S
L
Q
-----
A
L
E
C
-
P
Q
L
Q
A
D
Y
D
S
C
W
A
T
-
L
P
---
S
T
F
N
P
N
R
----
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------