@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0099: (2015-12-21 )
MANEVYANNMEISCKAANGKSIAAFPDVCFTPPQAPPTPLGVPIPYPNTGLSKDTTKGTRTIRITRKEVMLKNKSYYKTSYGDEPGRAPKKGIVTSKIKGKVYFTSWSMNVKFESKNVVRHLDLTTHNHASFPGNTPVWPYLDQATVDAGGGPCSNEVKKEKKDCADFKPHGSKDACAGLGAGKPSGKKTSNEADRLADKVAARKCLTARRCALQPYKPNSCCPQQTAHHLIEASALHDKGRGGKGSVPLKGISNYSENKAPCVCAEGVNQNVGTHGLMHTFQSAAAAKSRSGTLQLSNGSSISAKKTTYGTAKRQSMAAMGKVFPQSKCSKECLSAQLDNYHKQCGINARTPIKAVETGQTDVTAATQAIKTRNARLGATRSRVR
Atome Classification :
(17 SA)
---........---.10........20........30........40...-.....50........60-....----....---70........80.......-.90.......-.100......-.110---...-......120.-------.-.....130..----....-.140-........150...---..-----------..160.......170--.....--------....180......-------------------.190.......200....--...---------.210.......220.....--..230......------.240.......250.......260.....-----..270.......280.......290.......300.......310......-----.320.......330.......340.......350.......360........----.370.......380....--------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MAN
E
V
YAN---N
M
E
I
S
C
K
AANGKSIAAFPDVCFTPPQAPPTPLGVPI-PYPNTGLSKDTTKG
T
R
T
-
I
R
I
T
----
R
K
E
V
---MLKNK
S
Y
YKTSYGDEPGRA-PKKGIVTSKI-KG
K
V
Y
F
T
S
W
S
-
M
N
-----
V
K
F-ESKN
V
V
R
H
L
D-------L-TTHNHASFPG----NTPV-WPY--LDQATVDAGGGPC
S
---
N
E
-----------
V
K
K
E
K
K
DCADFKP----HGSK
D
--------
A
CAGLGAGKPSGK-------------------KTS
N
E
A
D
R
L
A
D
K
V
-
A
A
R
K
--
C
L
T
---------
A
R
R
CALQPYKPNSC
C
P
Q
Q
T
--
A
H
H
L
I
E
A
S
ALH------DKGRGGKGSVPLKGISNYSENKA
P
C
V
CAE-----GVNQNV
G
T
H
G
L
M
H
T
F
Q
S
A
A
AAKSRS
G
T
L
Q
LSNGSSISAKKTTYG
T
A
K
R
Q
S
M
-----
A
A
M
G
KVF
P
Q
S
K
C
S
K
E
C
L
S
A
Q
L
D
N
Y
H
K
QCGINARTP
I
K
A
VETG--Q
T
D
V
T
A
A
T
----
Q
A
I
K
TRNARLGATRSRVR--------------------------------------------------
14
Fugue
84.93
15%
22
- C8 -
4XGC
-
A:
[38-388]
------------------
P
C
R
E
R
E
F
E
N
I
Y
A
F
L
E
G
K
I
Q
D
Q
C
-----
M
Y
V
S
--
G
V
P
G
T
G
K
T
A
T
V
T
G
V
I
R
T
-----------------
L
Q
E
Y
L
E
I
N
G
M
R
L
T
E
P
R
Q
A
-
Y
V
Q
I
Y
K
Q
L
T
G
-
K
T
V
S
W
E
Q
A
H
A
-
L
L
-----
E
K
R
-
T
T
V
L
L
V
D
E
L
D
-------
I
-
L
C
N
R
R
Q
D
V
V
Y
----
N
L
L
D
-
W
P
T
--
K
L
V
V
V
T
I
A
N
T
M
D
L
P
---
E
R
-----------
L
G
L
T
R
L
T
F
---
Q
P
----
Y
S
H
K
Q
--------
L
Q
E
I
V
T
A
R
L
G
K
G
E
-------------------
A
V
Q
L
V
A
R
K
V
A
A
V
S
G
D
A
R
R
--
A
L
D
---------
I
C
R
R
A
T
E
I
A
D
T
A
A
V
-
K
C
V
T
--
M
L
H
V
Q
Q
A
L
A
E
M
------
I
A
S
---
A
K
V
Q
A
I
R
N
C
S
R
M
E
Q
I
F
L
Q
A
I
A
A
E
-----
V
T
R
T
G
V
E
E
T
T
F
M
G
V
Y
Q
Q
V
E
T
I
A
A
F
M
G
V
---------------------------------
T
F
P
P
P
G
R
A
L
R
L
C
S
K
L
G
A
E
R
-----------
L
I
I
S
E
H
S
R
--
N
D
L
F
Q
K
I
L
----
L
N
V
S
A
D
D
I
H
Y
A
L
R
V
------------------------------------------------------
20
Fugue
81.39
20%
30
- C3 -
4GA6
3
AMPPA_THEKO
A:
[1-493]
---
M
K
A
K
I
R
I
L
---
D
M
-
F
S
G
R
Y
T
V
L
I
N
E
E
D
A
K
E
A
K
L
H
P
D
D
L
V
K
I
E
A
G
K
K
A
-
V
Y
G
S
V
A
L
S
N
L
V
G
K
G
--
E
-
V
G
I
S
----
R
D
V
L
---
D
L
H
N
F
S
E
G
E
T
V
S
V
I
P
A
G
T
P
-
E
S
V
R
Y
I
K
K
K
M
-
H
G
E
K
L
-------------
R
K
V
-
E
I
E
A
I
V
R
D
I
V
-------
D
-
R
K
L
R
D
I
E
I
S
S
----
F
V
T
A
-
L
E
I
N
G
L
D
M
D
E
I
A
A
L
T
I
A
M
A
E
T
G
D
M
-----------
L
D
I
D
R
K
P
I
M
D
V
H
S
IGGV
P
G
N
K
T
N
I
L
V
V
P
I
V
A
A
A
G
L
T
I
P
K
T
S
S
R
A
ITSAAG
T
A
D
V
V
E
V
F
ADVS
F
S
L
D
E
I
K
R
I
V
E
K
V
-
G
A
----
C
L
V
WGGALNLA
P
A
D
D
I
T
I
K
A
E
R
A
L
S
I
D
P
T
G
L
M
L
A
S
I
M
S
K
K
Y
A
M
G
SQ
Y
V
L
I
D
I
P
T
G
K
G
V
K
V
E
T
V
E
E
A
R
S
L
A
R
D
F
I
E
L
G
K
R
L
G
Q
Y
V
E
V
A
I
T
Y
G
G
Q
P
I
G
H
T
V
G
P
A
L
E
A
R
E
A
L
S
A
L
M
T
G
K
G
P
G
S
L
I
E
K
A
T
G
L
A
G
I
L
L
E
M
G
GVAP
A
G
T
G
K
K
M
A
K
E
I
L
E
S
G
K
A
W
E
K
M
K
E
I
I
E
A
Q
G
G
D
P
N
I
K
P
E
E
I
P
I
G
D
K
T
Y
T
F
T
A
A
T
S
G
Y
V
T
A
I
D
N
R
A
I
T
A
I
A
R
A
A
G
A
P
EDKG
A
G
I
E
L
YVKVG
E
K
V
K
EGDPL
F
T
I
H
A
EH
E
A
R
L
D
Q
A
I
V
L
A
R
R
T
EPIRIE
16
Fugue
69.89
16%
27
- C5 -
2W0C
1
SPIKE_BPPM2
L:
[1-335]
---
M
I
V
K
K
K
L
A
---
A
G
E
F
A
E
T
F
K
N
G
N
N
I
T
I
I
K
A
V
----
G
E
L
V
L
R
A
Y
G
A
D
----
G
G
E
G
L
R
T
I
V
R
Q
G
V
S
I
-
K
G
M
N
----
Y
T
S
V
---
M
L
H
T
E
Y
A
Q
E
I
E
Y
W
V
G
D
L
D
Y
-
S
F
Q
----
E
Q
T
-
T
K
S
R
D
V
N
S
F
Q
-
I
P
-----
L
R
D
-
G
V
R
E
L
L
P
--
E
-------
D
-
A
S
R
N
R
A
S
I
K
S
----
P
V
D
I
-
W
I
G
--
G
E
N
M
T
--
A
L
N
G
I
V
D
---
G
G
-----------
R
K
F
E
A
G
Q
E
F
Q
I
N
T
----
F
G
S
V
N
--------
Y
W
V
-------------------------------
S
D
E
E
I
R
V
F
K
E
Y
-
S
A
R
A
KY
A
Q
N
---------
E
G
R
T
A
L
E
A
N
N
V
P
F
--
F
D
I
D
--
V
P
P
E
L
D
G
V
P
F
S
------
L
K
A
R
V
R
H
K
S
K
G
V
D
G
L
G
D
Y
T
S
I
S
V
K
P
A
F
Y
I
-----
T
E
G
D
E
--
T
T
D
T
L
I
K
Y
T
S
Y
G
S
T
G
S
H
S
G
Y
D
F
D
D
N
T
L
D
V
M
V
T
L
S
---------------
A
G
V
H
R
V
F
P
V
E
--
T
E
L
D
Y
D
A
V
Q
E
V
Q
H
D
W
Y
D
-
E
S
F
T
T
F
I
E
V
Y
S
D
--
D
P
L
L
T
V
K
G
----
Y
A
Q
I
L
M
E
R
T
-----------------------------------------------------------
13
Fugue
68.21
12%
1
- C8 -
4XR7
-
PAN3_YEAST
B:
[1-456]
MH
S
L
L
Q
Y
R
S
A
D
---
Q
L
F
I
P
N
N
I
R
E
D
L
T
K
K
N
L
S
I
L
Q
V
F
P
S
S
G
K
V
I
P
S
I
V
Q
----
D
Y
F
N
L
V
P
L
N
F
N
N
K
T
T
L
F
K
V
F
S
NYD
G
K
A
Y
---
V
L
K
R
L
P
N
I
D
K
S
M
N
P
N
K
I
S
K
-
I
Y
Q
I
W
S
K
I
N
C
-
T
N
L
I
K
F
R
D
I
F
-
Q
T
-----
T
K
F
-
G
D
L
S
I
C
L
V
F
D
Y
YPNSLS
L
-
Y
D
Y
H
F
V
N
F
P
K
FPIT
N
N
Y
L
-
W
I
Y
--
L
V
Q
L
T
N
V
I
N
S
I
H
S
Q
---
N
L
SIGNTLNWRKV
L
I
T
G
D
P
G
R
I
K
L
S
H
----
C
N
F
M
D
--------
L
L
F
N
--
D
D
T
D
T
V
V
-------------------
S
S
T
I
E
G
Q
Q
Q
L
D
Y
K
-
Y
L
G
E
--
L
L
F
---------
N
L
S
I
N
I
E
N
S
N
N
N
T
A
-
P
K
E
Y
--
R
L
E
E
I
T
P
Q
S
I
D
------
D
----------
M
R
Q
I
D
D
K
F
K
D
V
L
K
Y
L
I
S
D
-----
N
G
D
S
K
K
S
I
H
D
L
T
S
H
F
Y
D
K
M
F
M
V
L
E
S
S
Q
T
Y
T
E
Y
M
E
S
V
L
S
R
E
L
E
N
G
R
L
F
R
L
-
V
-----
N
K
L
N
C
I
F
G
R
I
E
S
R
I
D
-
I
N
W
S
E
S
G
T
K
F
P
I
I
L
F
Y
D
Y
V
F
H
Q
V
D
S
N
--
G
K
P
I
M
D
L
T
----
H
V
L
R
C
L
N
K
L
D
A
G
I
Q
E
K
L
M
L
V
TPDEL
N
C
I
I
I
S
Y
K
E
L
K
D
L
I
E
S
T
F
R
S
I
T
Q
H-------------------
18
Fugue
61.28
14%
48
- C8 -
4J72
3
MRAY_AQUAE
A:
[20-363]
---
F
A
F
N
V
L
K
Y
I
T
F
R
S
F
T
A
V
L
I
A
F
F
L
T
L
V
L
S
P
S
F
I
N
R
L
K
K
Y
T
P
T
M
G
G
I
V
I
----
L
I
V
V
T
L
S
T
L
L
L
M
R
W
-
D
I
K
Y
----
T
W
V
V
---
L
L
S
F
L
S
F
G
T
I
G
F
W
D
D
Y
V
K
L
K
N
K
K
G
I
---------------
S
-
I
K
-----
T
K
F
-
L
L
Q
V
L
S
A
S
L
I
-------
S
-
V
L
I
Y
Y
W
A
D
I
D
----
T
I
L
Y
-
F
P
F
--
F
K
E
L
Y
V
D
L
G
V
L
Y
L
P
---
F
A
-----------
V
F
V
I
V
G
S
A
N
A
V
N
L
----
T
D
G
L
D
-------------
G
L
A
I
G
P
A
M
-------------------
T
T
A
T
A
L
G
V
V
A
Y
A
V
-
G
H
S
K
--
I
A
Q
---------
Y
L
N
---
I
P
Y
V
P
Y
A
--------
G
E
L
T
V
F
C
F
A
L
V
------
G
A
G
L
G
F
L
W
F
N
S
F
P
A
Q
M
F
M
G
-------------------
D
V
G
S
L
S
I
G
A
S
L
A
T
V
A
L
L
T
K
S
E
F
I
F
A
V
A
A
G
V
F
V
F
E
T
I
S
V
I
L
Q
I
I
Y
F
R
W
-----
T
G
G
K
R
L
F
K
R
A
P
F
H
H
--------
H
L
E
L
N
G
L
P
E
P
K
I
V
V
R
M
W
I
I
S
--
I
L
L
A
I
I
A
I
----
S
M
L
K
----------------------------------------------------------------
17
Fugue
47.39
9%
29
- C6 -
4R03
4
?
A:
[1-109]
-----------------------------------------------------
G
K
D
Y
L
Y
D
T
K
E
E
N
G
K
I
-
I
S
K
V
----
V
F
L
Q
E
NG
L
L
N
K
Q
V
R
Y
E
F
Q
Y
-
N
E
N
G
K
V
-
S
E
K
K
A
F
R
W
D
R
-
T
N
D
E
W
V
P
F
Y
Q
-
I
T
-----
Y
Q
Y
D
D
Q
S
G
E
I
K
T
N
Y
-------
G
M
W
D
K
K
K
K
N
F
S
L
----
N
V
Q
N
M
I
I
P
--
S
T
N
Y
E
E
I
F
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
43.51
12%
59
- C9 -
1J0W
-
DOK5_HUMAN
A:
[9-107]
-----------------------------------------
Q
S
E
R
F
N
V
Y
L
M
P
S
P
N
L
-----
D
V
H
G
E
C
A
-
L
Q
I
T
----
Y
E
Y
I
---
C
L
W
D
V
Q
----
N
P
R
V
K
L
I
S
W
-
P
L
S
A
L
R
R
Y
G
R
D
T
T
W
F
T
F
E
A
G
R
M
C
E
T
G
E
G
L
F
I
F
-
Q
T
R
D
G
E
A
I
Y
Q
-------
K
-
V
H
S
A
A
L
A
I
A
E
----
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
39.63
27%
148
* C9 *
3EAB
-
CHM1B_HUMAN
G:
[148-196]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
D
M
L
L
----
Q
E
M
A
D
--------
E
-
A
G
L
D
T
G
S
V
G
T
S
-------------------
V
A
S
A
E
Q
D
E
L
S
Q
R
L
-
A
R
L
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
39.44
23%
166
* C8 *
1QG9
-
A:
[1-21]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
E
Y
T
F
T
G
I
Y
T
F
E
S
L
I
K
I
L
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
37.23
17%
30
- C4 -
2MUK
-
X:
[9-32]
------------------------------------------------------------------------------------------------------------------------------
V
K
-----
V
S
M
-
D
G
A
P
Y
L
R
K
I
D
-------
L
-
R
M
Y
K
S
Y
D
E
L
S
----
N
A
L
S
-
N
M
F
--
S
S
F
T
M
G
K
H
G
G
E
E
G
M
---
I
D
-----------
F
M
N
E
R
K
L
M
D
L
V
N
S
----
W
D
Y
V
P
--------
S
Y
E
N
K
D
G
N
W
M
L
V
G
-------------------
D
V
P
W
P
M
F
V
D
T
C
K
R
-
L
R
L
M
--
K
G
S
---------
D
A
I
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
35.34
22%
108
- C7 -
2DN5
-
A:
[29-51]
----------------------------------------------
P
V
L
V
-
P
Y
K
L
I
R
D
S
P
------
D
A
-
V
E
V
T
----
G
L
P
D
---
D
I
P
F
R
N
P
N
T
Y
D
I
H
R
L
E
K
I
L
-
K
A
R
E
H
V
R
M
V
I
-
I
N
Q
S
G
P
S
S
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
34.85
17%
104
- C7 -
2D99
-
A:
[29-51]
----------------------------------------------
V
V
P
L
-
P
Y
E
R
L
L
R
E
P
------
G
L
-
L
A
V
Q
----
G
L
P
E
---
G
L
A
F
R
R
P
A
E
Y
D
P
K
A
L
M
A
I
L
-
E
H
S
H
R
I
R
F
K
L
-
K
R
P
S
S
G
P
S
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
31.68
13%
126
* C7 *
2DZQ
-
A:
[29-51]
----------------------------------------------
P
V
K
V
-
P
Y
S
K
F
L
M
H
P
------
E
E
-
L
F
V
V
----
G
L
P
E
---
G
I
S
L
R
R
P
N
C
F
G
I
A
K
L
R
K
I
L
-
E
A
S
N
S
I
Q
F
V
I
-
K
R
P
E
L
L
T
E
G
V
-
K
E
-----
P
S
G
-
P
S
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
30.63
18%
120
- C7 -
2DZR
-
A:
[29-50]
----------------------------------------------
P
V
Q
V
-
P
Y
K
R
I
K
S
N
P
------
G
S
-
V
I
I
E
----
G
L
P
P
---
G
I
P
F
R
K
P
C
T
F
G
S
Q
N
L
E
R
I
L
-
A
V
A
D
K
I
K
F
T
V
-
T
R
P
F
Q
G
L
I
P
K
-
P
D
-----
E
S
G
-
P
S
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
21.10
50%
619
- C2 -
1KCN
1
?
A:
[14-21]
-----------------------------
L
C
P
D
V
C
Y
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
19.93
27%
89
- C7 -
2P14
1
?
A:
[72-97]
--------------------------------------------------------------------------------------------------------------------
I
E
C
S
L
T
I
G
E
-
K
Q
-----
L
D
Y
-
E
G
D
S
V
V
R
H
L
Q
-------
E
-
Y
K
K
K
G
I
E
A
Y
T
----
L
F
L
G
-
K
S
I
--
D
L
S
F
A
R
H
I
G
F
N
K
E
S
---
E
P
-----------
V
I
P
L
T
V
D
Q
F
K
K
L
V
----
T
Q
L
K
G
--------
D
G
E
H
F
N
P
N
K
L
K
E
I
-------------------
L
I
K
L
L
R
S
D
L
G
Y
D
Q
-
A
E
E
W
--
L
T
F
---------
I
E
Y
N
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
12.66
67%
960
- C1 -
1RPQ
-
?
W:
[15-20]
------------------------------
C
P
D
V
C
Y
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------