@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0168: (2015-12-24 )
MPSTLQGLAEYREEIRKSRFHTIAAPVADEDEAQAFIAAHRDASAGHNCWAWKCGAQYRFSDDGEPGGSAGRPILAAIEGQDMDCVAVLVSRWFGGIKLGTGGLARAYGGGAAKCLQQAPRSELVERCRVRFACAFADHALLKARSLALGASVAAEDYGADGVVLTLELPVARFEALQALLVDLSRGQVRPQRLDA
Atome Classification :
(20 SA)
--------------------------------------..---.......10........-------------20...--------.....30......----..--------40..--..-....50..--------...-----...60.---.......70........80........--90...----.....100----........110-----------.........120--..-......---130......----.140....---------------...150.......--160.-........170.-.-.-----...---.180.......190....-----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------M
P
---
S
T
L
Q
G
L
A
E
Y
R
E
E
I
R
KSR-------------F
H
T
IA--------APVA
D
E
D
E
A
Q
A
F
I
----
A
A--------HRDA--SA-GHN
C
W
A
W
K--------CGA-----
Q
Y
RFSD---DGEPGGSAGR
P
I
L
A
A
IEGQ
D
M
D
C
V
A
V
L
--
V
S
R
W
F----G
G
I
K
LGT-----GG
L
A
R
AYGG-------------
G
A
A
K
C
L
Q
QA
P
R
---
S
E
-
L
V
E
R
C
R
---
V
R
F
A
C
AFAD----
H
A
L
L
K
A
R
S
---------------LALGASVAAEDYG--A--D-
G
V
V
L
T
L
EL
P
V
A
R
-
F
-
E
-----
A
L
Q
---
A
L
L
V
D
LSRGQVRPQRLDA-----------------------------
8
HHSearch
97.82
52%
-101
- C7 -
2CVE
2
?
A:
[2-191]
---------------------------------------
S
---
L
T
L
A
D
K
V
V
Y
E
E
E
I
Q
K
S
R
-------------
F
I
A
K
A
--------
A
P
V
A
S
E
E
E
A
L
A
F
L
----
A
E
--------
N
R
E
P
--
E
A
-
T
H
N
G
H
A
Y
K
--------
I
G
L
-----
L
Y
R
F
S
D
---
D
G
E
P
S
G
T
A
G
R
P
I
L
H
A
I
E
A
Q
G
L
D
R
V
A
V
L
--
V
V
R
Y
F
----
G
G
V
K
L
G
A
-----
G
G
L
V
R
A
Y
G
G
-------------
V
A
A
E
A
L
R
R
A
P
K
---
V
P
-
L
V
E
R
V
G
---
L
A
F
L
V
P
F
A
E
----
V
G
R
V
Y
A
L
L
---------------
E
A
R
A
L
-
K
A
E
E
T
Y
T
--
P
--
E
-
G
V
R
F
A
L
L
L
P
K
P
E
-
R
-
E
-----
G
F
L
---
R
A
L
L
D
A
T
R
G
Q
V
A
L
E
---------------------------------
1
PsiBlast_PDB
96.94
53%
-109
- C7 -
2CVE
2
?
A:
[2-188]
---------------------------------------
S
---
L
T
L
A
D
K
V
V
Y
E
E
E
I
Q
K
S
R
-------------
F
I
A
K
A
--------
A
P
V
A
S
E
E
E
A
L
A
F
L
----
A
E
--------
N
R
E
P
--
E
A
-
T
H
N
G
H
A
Y
K
--------
I
G
L
-----
L
Y
R
F
S
D
---
D
G
E
P
S
G
T
A
G
R
P
I
L
H
A
I
E
A
Q
G
L
D
R
V
A
V
L
--
V
V
R
Y
F
----
G
G
V
K
L
G
A
-----
G
G
L
V
R
A
Y
G
G
-------------
V
A
A
E
A
L
R
R
A
P
K
---
V
P
-
L
V
E
R
V
G
---
L
A
F
L
V
P
F
A
E
V
G
R
V
Y
A
L
L
E
A
R
A
---------------
L
K
-----
A
E
E
T
Y
T
--
P
--
E
-
G
V
R
F
A
L
L
L
P
K
P
E
-
R
-
E
-----
G
F
L
---
R
A
L
L
D
A
T
R
G
Q
V
A
L
E
---------------------------------
2
PsiBlast_PDB
85.54
37%
-100
- C7 -
1VI7
-
YIGZ_ECOLI
A:
[18-201]
-----------------------------------------------------
E
E
I
K
K
S
R
-------------
F
I
T
M
L
--------
A
H
T
D
G
V
E
A
A
K
A
F
V
E
S
V
R
A
E
--------
H
P
D
A
--
R
---
H
H
C
V
A
W
V
--------
A
G
A
PDDSQ
Q
L
G
F
S
D
---
D
G
E
P
A
G
T
A
G
K
P
M
L
A
Q
L
M
G
S
G
V
G
E
I
T
A
V
--
V
V
R
Y
Y
----
G
G
I
L
L
G
T
-----
G
G
L
V
K
A
Y
G
G
-------------
G
V
N
Q
A
L
R
Q
L
T
T
---
Q
R
-
K
T
P
L
T
E
---
Y
T
L
Q
C
E
Y
H
Q
----
L
T
G
I
E
A
L
L
---------------
G
Q
C
D
G
K
I
I
N
S
D
Y
Q
--
A
----
F
V
L
L
R
V
A
L
P
A
A
K
-
V
-
A
-----
E
F
S
---
A
K
L
A
D
F
S
R
G
S
L
Q
L
L
A
I
E
E
-----------------------------
29
Fugue
85.16
34%
-90
- C7 -
1VI7
-
YIGZ_ECOLI
A:
[3-208]
--------------------------------------
L
M
E
S
W
L
I
P
A
A
P
V
T
V
V
E
E
I
K
K
S
R
-------------
F
I
T
M
L
--------
A
H
T
D
G
V
E
A
A
K
A
F
V
----
E
S
--------
V
R
A
E
H
P
D
A
-
R
H
H
C
V
A
W
V
--------
A
G
A
PDDSQ
Q
L
G
F
S
D
---
D
G
E
P
A
G
T
A
G
K
P
M
L
A
Q
L
M
G
S
G
V
G
E
I
T
A
V
--
V
V
R
Y
Y
----
G
G
I
L
L
G
T
-----
G
G
L
V
K
A
Y
G
G
-------------
G
V
N
Q
A
L
R
Q
L
T
T
---
Q
R
-
K
T
P
L
T
E
---
Y
T
L
Q
C
E
Y
H
Q
----
L
T
G
I
E
A
L
L
---------------
G
Q
C
D
G
K
I
I
N
S
D
Y
Q
-----
A
-
F
V
L
L
R
V
A
L
P
A
A
K
-
V
-
A
-----
E
F
S
---
A
K
L
A
D
F
S
R
G
S
L
Q
L
L
A
I
E
E
E----------------------------
20
HHSearch
60.87
14%
-115
- C7 -
2WBM
4
SDO1_METTH
A:
[119-251]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
R
L
K
I
I
N
K
--
I
A
R
E
A
INPQ
N
G
L
P
H
P
P
-----
K
R
I
E
K
A
M
E
E
A
R
V
H
V
D
PFKT
V
D
E
Q
V
N
I
V
L
K
A
I
R
T
K--
I
P
I
K
F
E
K
V
R
---
V
A
I
K
I
P
G
E
M
----
A
G
S
A
Y
G
V
I
---------------
S
N
F
G
-
K
I
T
N
E
E
W
Q
--
N
--
D
G
S
W
I
A
V
V
E
I
P
G
G
L
-
Q
-
D
-----
S
F
Y
---
Q
K
L
S
E
L
T
G
G
N
V
E
T
R
L
I
K
------------------------------
31
Fugue
53.92
14%
-58
* C6 *
2FOK
-
T2F1_PLAOK
A:
[387-579]
--------------------------------------
K
S
---
E
L
E
E
K
K
S
E
L
R
H
K
L
K
Y
V
P
-------------
H
E
Y
I
E
--------
L
I
E
I
A
R
N
S
T
Q
D
R
I
----
L
E
--------
M
K
V
M
--
E
F
-
F
M
K
V
Y
G
Y
R
-------------------------
G
K
H
L
G
G
S
R
K
P
D
G
A
I
Y
T
V
G
S
P
I
D
Y
G
V
I
V
--
D
T
K
A
Y
S
---
G
G
Y
N
L
-
P
-----
I
G
Q
A
D
E
M
Q
R
-------------
Y
V
E
E
N
Q
T
R
N
K
H
INP
N
E
-
W
W
K
V
Y
P
SSV
T
E
F
K
F
L
F
V
S
----
G
H
F
--
K
G
N
---------------
Y
K
A
Q
L
T
R
L
N
H
I
T
N
--
C
--
N
-
G
A
V
L
S
V
E
E
L
L
I
G
-
G
-
E
-----
M
I
K
---
A
G
--
T
L
T
L
E
E
V
R
R
K
F
N
N
G
EINF-------------------------
3
PsiBlast_PDB
53.70
23%
-99
- C5 -
1O75
3
TA47_TREPA
A:
[254-413]
-----------------------------------------------------------
N
-------------
F
N
T
V
R
--------
Y
D
Y
Y
G
D
D
A
S
Y
T
N
L
----
M
A
--------
S
Y
G
T
--
K
H
-
S
A
D
S
W
-
W
K
TGRVP
R
I
S
C
G
I
-----
N
Y
G
F
-----
D
R
F
K
G
S
G
P
G
Y
Y
R
L
T
L
I
A
N
G
Y
R
D
V
V
A
D
V
R
F
L
P
K
Y
E
----
G
N
I
D
I
G
L
-----
K
G
K
V
L
T
I
G
G
-------------
A
D
A
E
T
L
M
D
A
A
-------------------
V
D
V
F
A
D
GQ--
P
K
L
V
S
D
Q
A
---------------
V
S
L
G
Q
N
V
L
S
A
D
F
---
T
--
P
-
G
T
E
Y
T
V
E
V
R
F
K
E
-
F
-
G
-----
S
V
R
---
A
K
V
V
A
------------------------------------------
33
Fugue
53.03
16%
-44
- C6 -
1O57
6
PURR_BACSU
A:
[2-276]
KFR
R
S
G
R
L
V
D
L
T
N
Y
L
L
T
H
PH
E
L
I
P
L
T
F
F
S
E
R
Y
ESA
K
S
S
I
S
---
E
D
L
T
I
I
K
Q
T
F
E
Q
Q
G
I
G
T
-------------
L
L
T
V
P
G
AA
G
G
V
K
Y
I
P
K
M
K
Q
A
E
A
E
E
F
V
----
Q
T
--------
L
G
Q
S
--
L
A
-
N
P
E
R
--
I
L
--------
P
G
G
-----
Y
V
Y
L
T
D
I
L
G
K
P
S
V
L
S
K
V
G
K
L
F
A
S
V
F
A
E
R
E
I
D
V
V
M
T
V
--
A
T
K
-------
G
I
P
L
A
Y
-----
A
-
A
A
S
Y
L
N
V
-------------
P
V
V
I
V
R
K
D
G
S
T
---
V
S
-
I
N
Y
V
S
G
---
S
S
N
R
---
I
Q
----
T
M
S
L
A
K
R
S
---------------
M
K
T
G
S
N
V
L
I
I
D
D
F
MK
A
--
G
-
G
T
I
N
G
M
I
N
L
L
D
E
-
F
-
N
-----
A
N
V
A
G
I
G
V
L
V
E
A
E
G
V
D
E
R
L
V
D
E
Y
M
S
L
L
T
L
S
TINMKEK
S
I
E
I
Q
NGN
F
L
R
F
F
KDN
11
HHSearch
52.73
12%
-99
- C7 -
1DAR
-
EFG_THET8
A:
[587-670]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
-------------
A
I
K
E
A
V
Q
K
G
D
P
---
V
I
-
L
E
P
I
M
R
---
V
E
V
T
T
P
E
E
Y
----
M
G
D
V
I
G
D
L
---------------
N
A
R
R
G
Q
I
L
G
M
E
P
R
--
G
--
N
-
A
Q
V
I
R
A
F
V
P
L
A
E
-
M
-
F
-----
G
Y
A
---
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
-----------------------------
34
Fugue
51.40
16%
-61
- C6 -
4Q7O
8
?
A:
[4-136]
-------------------------------------M
K
N
---
N
I
F
L
N
L
N
K
K
S
I
N
N
N
H
F
V
-------------
I
S
I
F
F
--------
E
T
I
Y
Q
F
E
T
K
D
T
L
L
----
E
C
--------
F
K
N
I
--
T
T
T
G
H
F
G
V
I
-----------
G
A
-----
Q
Y
E
K
I
D
---
A
-----------------------------
T
R
W
I
----
G
D
Y
E
E
V
N
-----
G
-------------------------------------------------------
F
----
E
Y
I
D
K
A
P
S
---------------
I
Y
F
S
V
G
---
D
D
F
N
--
P
--
E
-
E
L
I
I
P
I
N
L
A
Y
H
Y
-
F
-
N
I
----
A
I
S
---
D
F
L
I
A
H
P
E
Y
Q
K
K
C
K
E
I
Q
K
T
Y---------------------------
19
HHSearch
51.27
17%
-94
- C7 -
3CB4
-
LEPA_ECOLI
D:
[398-469]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
-
R
E
P
I
A
E
---
C
H
M
L
L
P
Q
A
Y
----
L
G
N
V
I
T
L
C
---------------
V
E
K
R
G
V
Q
T
N
M
V
Y
H
--
G
--
N
-
Q
V
A
L
T
Y
E
I
P
M
A
E
V
V
-
L
-----
D
F
F
---
D
R
L
K
S
T
S
R
G
Y
A
S
L
D
Y
N
F
K
-----------------------------
13
HHSearch
50.57
15%
-99
- C7 -
1N0U
1
EF2_YEAST
A:
[702-795]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
G
Q
I
I
P
T
M
R
R
-------------
A
T
Y
A
G
F
L
L
A
D
P
---
K
I
-
Q
E
P
V
F
L
---
V
E
I
Q
C
P
E
Q
A
----
V
G
G
I
Y
S
V
L
---------------
N
K
K
R
G
Q
V
V
S
E
E
Q
----T-
P
-
L
F
T
V
K
A
Y
L
P
V
N
E
-
S
-
F
-----
G
F
T
---
G
E
L
R
Q
A
T
G
G
Q
A
F
P
Q
M
V
F
D
-----------------------------
21
HHSearch
50.40
13%
-105
- C7 -
2YWE
-
LEPA_AQUAE
A:
[404-474]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
P
F
V
L
---
V
T
I
I
T
P
K
E
Y
----
V
G
P
I
I
Q
L
C
---------------
Q
E
K
R
G
I
Q
K
N
M
T
Y
L
D-
P
--
N
-
T
V
Y
L
E
Y
E
M
P
L
S
E
-
I
I
V
-----
D
F
H
---
D
K
I
K
S
I
S
R
G
F
A
S
Y
D
Y
E
F
I
-----------------------------
15
HHSearch
48.51
14%
-84
- C7 -
2DY1
-
?
A:
[556-640]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
-------------
A
F
K
K
V
M
A
E
A
H
P
---
V
L
-
L
E
P
I
Y
R
---
L
K
V
L
A
P
Q
E
R
----
V
G
D
V
L
S
D
L
---------------
Q
A
R
R
G
R
I
L
G
M
E
Q
E
--
G
--
A
-
L
S
V
V
H
A
E
V
P
L
A
E
-
V
-
L
-----
E
Y
Y
---
K
A
L
P
G
L
T
G
G
A
G
A
Y
T
L
E
F
S
-----------------------------
10
HHSearch
47.40
11%
-91
- C7 -
3J25
-
TET1_ENTFL
A:
[515-603]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
M
L
A
P
I
-------------
V
L
E
Q
V
L
K
K
A
G
T
---
E
L
-
L
E
P
Y
L
S
---
F
K
I
Y
A
P
Q
E
Y
----
L
S
R
A
Y
N
D
A
---------------
P
K
Y
C
A
N
I
V
D
T
Q
L
K
--
N
--
N
-
E
V
I
L
S
G
E
I
P
A
R
C
-
I
-
Q
-----
E
Y
R
---
S
D
L
T
F
F
T
N
G
R
S
V
C
L
T
E
L
K
-----------------------------
30
Fugue
47.35
17%
-77
- C3 -
1D06
1
FIXL_RHIME
A:
[1-130]
-------------------------------------------
G
S
H
M
L
E
T
E
D
V
V
R
A
R
D
A
H
-------------
L
R
S
I
L
--------
D
T
V
P
D
----------------------------------------------------------------------------------------
A
T
V
--
V
S
A
T
D
----
G
T
I
V
S
F
N
-----
A
A
A
V
R
Q
F
G
Y
-------------
A
E
E
E
V
I
G
Q
N
L
R
----
I
-
L
M
P
E
P
Y
---
R
H
E
H
D
G
Y
L
Q
----
R
Y
M
A
T
G
E
K
---------------
R
I
I
G
I
D
R
V
V
S
G
Q
R
--
K
--
D
-
G
S
T
F
P
M
K
L
A
V
G
E
-
M
-
R
S
GG
E
R
F
F
T
---
G
F
I
R
D
L
T
----------------------------------------
14
HHSearch
46.72
8%
-85
- C7 -
2XEX
-
EFG_STAAU
A:
[585-669]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
-------------
A
L
K
E
A
A
K
K
C
D
P
---
V
I
-
L
E
P
M
M
K
---
V
T
I
E
M
P
E
E
Y
----
M
G
D
I
M
G
D
V
---------------
T
S
R
R
G
R
V
D
G
M
E
P
R
--
G
--
N
-
A
Q
V
V
N
A
Y
V
P
L
S
E
-
M
-
F
-----
G
Y
A
---
T
S
L
R
S
N
T
Q
G
R
G
T
Y
T
M
Y
F
D
-----------------------------
16
HHSearch
46.54
12%
-79
- C7 -
3JB9
-
?
B:
[817-912]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
G
-----
G
Q
I
I
P
T
A
R
R
-------------
V
C
Y
S
S
F
L
T
A
S
P
---
R
L
-
M
E
P
V
Y
M
---
V
E
V
H
A
P
A
D
S
----
L
P
I
I
Y
D
L
L
---------------
T
R
R
R
G
H
V
L
Q
D
I
P
R
--
P
GS
P
-
L
Y
L
V
R
A
L
I
P
V
I
D
-
S
-
C
-----
G
F
E
---
T
D
L
R
V
H
T
Q
G
Q
A
M
C
Q
M
V
F
D
-----------------------------
36
Fugue
43.57
10%
-75
- C2 -
3B8M
-
?
A:
[64-330]
------------------------------K
W
T
S
A
A
V
V
T
P
---
P
E
P
V
Q
W
Q
E
L
E
K
T
F
T
K
L
R
V
L
D
L
D
I
K
ID
R
T
E
A
F
N
L
F
I
--------
K
K
F
Q
S
V
S
L
L
E
E
Y
L
----
R
S
S
P
Y
V
M
D
QD
E
L
D
L
--
H
R
-
A
I
V
A
L
S
E
K
--------
M
K
A
-----
V
D
D
N
A
S
---
K
K
K
D
E
P
S
L
Y
T
S
W
T
L
S
F
T
A
P
T
S
E
E
A
Q
T
V
--
L
S
G
Y
I
----
D
Y
I
S
A
L
V
V
K
E
S
I
E
N
V
R
N
K
L
E
I
-------------
K
T
Q
F
E
K
E
K
L
A
Q
---
D
R
-
I
K
M
K
N
Q
---
L
D
A
N
I
Q
R
L
N
----
Y
S
L
D
I
A
N
A
A
GIKKPVYKDDPDFS
I
S
L
G
A
D
G
I
E
R
K
L
E
--
I
--
E
-
K
A
V
T
D
V
A
E
L
N
G
E
-
L
-
R
-----
N
R
Q
---
Y
L
V
E
Q
L
T
K
A
N
I
N
D
V
N
F
T
P
FKYQLSPSLP-------------------
17
HHSearch
41.97
13%
-40
- C7 -
1T95
-
SDO1_ARCFU
A:
[168-237]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
E
---
I
A
I
K
I
P
P
E
H
----
T
G
R
A
I
S
A
L
---------------
Y
N
F
-
G
G
V
T
R
E
E
W
Q
R-
D
--
G
-
S
W
I
C
V
M
R
I
P
S
G
M
-
Y
-
G
-----
D
L
M
---
D
L
L
G
K
V
A
K
G
E
A
L
T
K
V
L
R
R
-----------------------------