@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0172: (2015-12-24 )
MAANWGLRGKSVVALLLACALALVPAVLLGWRAMDDIRTHFGLAYAKNFTLLHRQKILAPVSRELALSRRFAESVVTRDWLLKEDDPARRALFFREAEGYRGDFRDHAYFIIASGSHHYYFNDGRQPYSERPRYTLEAGDPEDAWYFNTLRNSAAYNINVNVDSKLNLTKVWFNLVIRDQGRPIGLAGSGLDLSGFLDDFIIAREPGVTPMIVGDDGAIQAHPDRRLIAYSSAAGGASERHRVFDLLDQPEQRDALREAMRLARAKAGSVHCLWAGLDGRQQLFAVAYIPQLRWYVLTAVDLHAAQVLDNRWLWPLAGTFLLLLVALLLGFAYAVERLLLRPLRSLKRSAKAIAAGRYDTPLPLARQDEIGSLSKAFASMADQVRRHTAELEDKVQERTQALEEANREMAAAQKKIGDSLDYASLIQRAILPDRQLSATLGEHHFILWKPRDVVGGDFYVYREQADGYLIGVVDCAGHGVPGALMTMLARAAIDHAIEAVGSRDPAAILGETDQAMRSMLSQEQIPQALATNMDAGLVWVDRRRRQLAFAGAKISLYASDGEEVQELKGARRAIGDKRRGDYRNIEVPLAPGWTFYLSTDGFLDQAGGEHGFGFGSRRFADMLRDHARQPLPEQAEAFVATLAEYQGEHPQRDDITILSFRFD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......--180.......190.......200...-....----210.......220....-.-..230.......240.......250.....-..260....-.-..270-...---.....-----.280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430-........440.......450---.......460...-....-470......-.-480.......490........500----...---.----...----..510--.........520....-...530.......540-.......550..-.--....560.-......-----------------------570--------------------------.-----------------------------------.---------------------------..--------....--580.......-590.......600.......610.......620....-...630.......640........650.......660.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAANWGLR
G
K
S
V
V
A
L
L
L
A
C
A
L
A
L
V
P
A
V
L
L
G
W
R
A
M
D
D
I
R
T
H
F
G
L
A
Y
AK
N
F
T
L
L
H
R
Q
K
I
L
A
P
V
S
R
E
L
A
L
S
R
R
F
A
E
S
V
V
T
R
DWLLKEDDP
A
R
R
A
L
F
F
REAEGYRGDFRD
H
A
Y
F
I
I
ASGS
H
H
Y
Y
FNDGRQPYSERP
R
Y
T
L
EAGDPED
A
W
Y
F
N
TLRNS
A
A
Y
N
I
N
V
N
VDSKL
N
L
T
K
V
W
F
N
L
V
I
RD--QGRPIGLAGSGL
D
L
S
G
F
L
D
D
F
IIARE-PGV
T
----
P
M
I
VGDDG
A
I
QAHPD
R
R
-
L
-
I
A
Y
SSAAGGA
S
E
R
H
R
V
F
D
L
LDQP
E
Q
R
D
A
L
R
-
E
A
M
R
L
A
RAK-A-G
S
V
---
H
C
L
---WAGLD-----GR
Q
Q
L
F
A
V
A
Y
IPQ
L
R
W
Y
V
L
T
A
V
D
L
H
A
A
Q
V
LDNRWL
W
P
L
A
G
T
F
L
L
L
L
V
A
L
L
L
G
F
A
Y
A
V
E
R
L
L
L
R
P
L
R
S
L
K
R
S
A
K
A
I
AAGRYDTPLPLAR
Q
D
EI
G
S
L
S
K
A
F
A
S
M
A
D
Q
V
R
R
H
T
A
E
L
E
D
K
V
Q
E
R
T
Q
A
L
E
E
A
N
R
E
M
A
A
A
Q
K
KIGDSL
D
Y
A
S
L
I
Q
R
AI-L-P
D
R
Q
L
S
A
TLGEH
H
F
I
L
WKPRD---VVGG
D
F
Y
V
Y
R
EQA-D
G
Y
L
-
I
G
V
VDCAGH-G-V
P
G
A
L
M
T
M
L
A
R
A
-
A
I
D
H
A
I
E
A
V------GSR---
D
----
P
A
A
----ILG----
E
T
D
Q
A
M
R
S
M
L
S
Q
E
Q
I
P
-
Q
A
L
A
TNMDA
G
L
V
W
V
D
R
-R
R
R
Q
LAFAG
A
K
I
-
S
--
L
Y
ASD
G
E
E
-
V
Q
E
L
K
G
-----------------------
A
R
---------------------------
R
-----------------------------------A---------------------------IG--------DKRR--GDYRNI
E
V
PL-APG
W
T
F
Y
LSTDGFLDQAGGEHGFGF
G
S
R
R
F
A
D
M
L
R
D
H-ARQPL
P
E
Q
A
E
A
F
V
A
T
-
L
A
E
YQGEHPQRD
D
I
T
I
L
S
F
RFD
23
HHSearch
90.01
17%
-69
- C1 -
3KE6
2
Y1364_MYCTU
A:
[21-256]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
F
Q
G
A
M
-
V
-
S
V
P
V
-
V
--
P
G
A
D
I
A
A
E
Y
L
V
A
A
EDT
A
A
G
G
D
W
F
D
A
L
A
L
G
-
D
R
L
V
-
L
V
V
G
D
V
V
G
H
-
G
-
V
E
A
A
A
V
M
S
Q
L
R
T
-
A
L
R
M
Q
I
S
A
--------
G
Y
---
T
----
V
V
E
----
A
L
E
----
A
V
D
R
F
H
K
Q
V
-
P
G
--------
S
K
S
A
T
M
C
V
G
S
L
D
F
-
T
S
G
E
F
Q
Y
C
T
A
G
H
-
P
P
P
L
L
V
T
A
D
A
S
-
A
R
Y
V
E
P
T----------------------
G
A
---------------------------
G
-----------------------------------
P
---------------------------
L
G
--------
S
G
T
G
----
F
P
V
R
S
E
V
L
-
N
I
G
D
A
I
L
F
Y
T
D
G
L
I
E
R
P
-
G
R
P
L
E
-
A
S
T
A
E
F
A
D
L
A
A
S
I
-
A
S
---
A
R
P
I
D
R
L
C
S
D
T
L
E
L
L
L
R
S
T
G
Y
N
D
D
V
T
L
L
A
M
Q
R
R
29
HHSearch
83.11
18%
-78
- C1 -
2J82
3
?
A:
[13-240]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
---
K
S
N
Q
D
A
F
Y
I
D
E
K
--
H
Q
R
F
-
F
I
V
A
D
G
M
-----
A
G
G
E
E
A
S
R
L
A
V
D
-
H
I
R
Q
Y
L
E
T
H
LED---
L
Q
H
---
D
----
P
V
T
L
L
R
Q
A
F
-----
A
A
N
H
A
I
V
E
Q
Q
R
Q
N
S
A
---
R
A
D
M
G
T
T
A
V
V
I
L
L
D
E
-
K
G
D
R
A
W
C
A
H
V
G
D
-
S
R
-
I
Y
R
W
R
K
D
Q
-
L
Q
Q
I
T
S
-----------------------
D
H
TWIAQARHVLS----------------
Q
-----------------------------------
C
---------------------------
L
G
--------
R
E
D
L
--
S
Q
I
D
I
Q
P
I
D
L
-
E
P
G
D
R
L
L
L
C
S
D
G
L
T
E
E
L
T
D
--------
D
V
I
S
I
Y
L
S
E
----
P
N
V
Q
K
A
A
A
A
L
V
D
A
-
A
K
T
H
----
G
G
R
D
N
V
T
V
V
V
I
S
V
-
40
HHSearch
82.15
16%
-67
* C1 *
2IQ1
1
PPM1K_HUMAN
A:
[20-262]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
N
E
D
R
F
D
F
A
Q
L
T
D
E
V
L
Y
-
F
A
V
Y
D
G
H
G
G
-
P
-
A
A
A
D
F
C
H
T
H
M
E
K
-
C
I
M
D
L
L
P
K
--------
E
K
---
N
----
L
E
T
----
L
L
T
L
A
F
L
E
I
D
K
A
F
S
S
H
A
R
L
---
A
-
T
L
L
T
S
G
T
T
A
T
V
A
L
L
R
D
--
G
I
E
L
V
V
A
S
V
G
D
-
S
R
-
A
I
L
C
R
K
G
K
-
P
M
K
L
T
I
-----------------------
D
H
---------------------------
T
PER
K
D
E
K
E
R
I
K
K
C
G
G
F
V
A
W
N
SLG
Q
P
H
V
NGRLAMTR
S
---------------------------
I
G
DLDLKTSG
V
I
A
E
--
P
E
T
K
R
I
K
L
H
H
-
A
D
D
S
F
L
V
L
T
T
D
G
I
N
F
M
V
N
--------
S
Q
E
I
C
D
F
V
N
Q
C
-
H
--
D
P
N
E
A
A
H
A
V
T
E
Q
-
A
I
Q
----
Y
G
T
E
D
N
S
T
A
V
V
V
P
F
G
33
HHSearch
79.14
15%
-56
- C1 -
3E4O
2
DCTB_RHIME
A:
[52-301]
-------------------------------------------
G
Q
S
R
I
D
A
S
L
K
A
S
L
L
R
A
V
V
E
R
Q
R
A
L
P
L
V
L
A
D
D
A
A
I
R
G
A
L
L
S
P
D
R
P
S
-
L
D
R
I
N
R
K
L
E
A
L
A
T
S
A
E
A
A
V
I
Y
L
I
D
R
-
S
G
V
A
V
A
A
S
N
W
Q
E
P
----
T
S
F
V
G
N
D
Y
A
F
R
D
Y
F
R
L
A
V
R
D
G
M
A
--
E
H
F
A
M
G
T
V
S
K
R
P
G
L
Y
I
S
R
R
V
D
G
--
P
G
G
P
L
G
V
I
V
A
K
L
E
F
D
G
V
E
A
D
W
Q
A
----
S
G
K
P
----
A
Y
V
T
D
R
R
G
I
V
L
I
T
S
L
P
S
-
W
-
R
F
M
T
T
K
P
I
A
E
D
R
L
A
P
I
R
E
S
L
Q
--
F
G
D
A
P
L
L
-
P
L
P
F
R
K
I
E
A
R
P
-
D
G
S
---
S
T
L
D
A
L
L
P
G
D
S
-----
T
A
A
F
L
R
V
E
T
M
V
P
S
T
N
W
R
L
E
Q
L
S
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
75.48
19%
-51
- C1 -
3PU9
3
?
A:
[16-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
T
H
K
F
G
T
---
R
E
S
G
D
T
V
E
L
V
E
R
P
G
G
G
F
S
-
A
V
L
V
D
G
Q
G
S
-
G
-
A
G
A
K
R
L
S
L
L
V
A
G
-
A
A
V
R
L
L
N
E
--------
G
V
---
R
----
D
G
A
----
A
A
R
----
A
A
H
D
F
L
Y
A
M
R
D
G
--------
K
V
S
A
A
L
D
I
L
S
V
D
L
-
A
S
R
S
V
L
V
T
R
N
S
E
-
V
P
-
M
L
L
G
R
N
G
E
-
F
E
Q
I
S
E
-----------------------
S
G
---------------------------
G
-----------------------------------
R
---------------------------
I
G
--------
I
Y
R
H
--
T
R
P
R
V
L
E
F
P
A
-
E
P
G
L
T
V
I
L
V
S
D
G
I
I
G
A
G
G
-
R
R
G
Q
P
L
E
--
F
L
A
T
G
G
R
V
A
G
P
E
T
P
A
Q
A
I
A
D
E
L
L
E
A
-
A
L
V
A
D
-
D
G
R
A
G
D
D
M
T
V
V
V
L
R
L
R
27
HHSearch
75.28
18%
-69
- C1 -
3W42
1
RSBX_BACSU
A:
[16-199]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
N
K
E
G
K
---
S
I
C
G
D
S
F
F
M
K
A
D
D
-
K
E
L
I
-
C
A
V
A
D
G
L
G
S
-
G
-
S
L
A
N
E
S
S
A
A
I
K
D
-
L
V
E
N
Y
A
S
----------
E
---
D
----
V
E
S
----
I
I
E
----
R
C
N
Q
A
M
K
N
K
------------
R
G
A
T
A
S
I
L
K
I
N
F
-
E
Q
R
Q
F
T
Y
C
S
V
G
N
-
V
R
F
I
L
H
S
P
S
G
E
S
F
Y
P
L
P
I
-----------------------
S
G
---------------------------
Y
-----------------------------------
L
---------------------------
S
G
--------
K
--
P
--
Q
K
Y
K
T
H
T
A
T
Y
-
E
K
G
S
K
F
I
I
H
T
D
G
L
N
V
------------
P
D
I
R
S
H
L
K
K
G
---
Q
S
V
E
E
I
S
N
S
L
K
M
-----
Y
T
--
T
S
R
K
D
D
L
T
Y
I
L
G
Q
L
S
37
HHSearch
71.04
15%
-76
- C1 -
1TXO
3
PSTP_MYCTU
A:
[19-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
E
D
S
V
Y
A
-----
G
A
R
L
-
L
A
L
A
D
G
M
G
G
-
H
-
A
A
G
E
V
A
S
Q
L
V
I
A
-
A
L
A
H
L
D
D
D
E
------
P
G
G
---
D
L
L
A
K
L
D
A
----
A
V
R
----
A
G
N
S
A
I
A
A
Q
V
E
M
E
P
D
---
L
E
G
M
G
T
T
L
T
A
I
L
F
A
---
G
N
R
L
G
L
V
H
I
G
D
-
S
R
-
G
Y
L
L
R
D
G
E
-
L
T
Q
I
T
K
-----------------------
D
D
---------------------------
T
F
V
Q
T
L
V
D
E
GRIT
P
E
E
A
H
S
HPQRSLIMR--------
A
---------------------------
L
T
--------
G
H
E
---
V
E
P
T
L
T
M
R
E
A
-
R
A
G
D
R
Y
L
L
C
S
D
G
L
S
D
P
V
S
--------
D
E
T
I
L
E
A
L
Q
I
----
P
E
V
A
E
S
A
H
R
L
I
E
L
-
A
L
R
----
G
G
G
P
D
N
V
T
V
V
V
A
D
L
E
31
HHSearch
70.49
16%
-63
- C1 -
2JFR
6
?
A:
[28-234]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
I
L
-
Y
A
V
A
D
G
F
G
A
R
G
H
H
A
S
A
T
A
L
K
T
L
S
A
-
G
F
A
A
A
P
---------
D
R
D
---
G
----
L
L
E
----
A
V
Q
----
Q
A
N
L
R
V
F
E
L
L
G
D
E
P
-----
T
V
S
G
T
T
L
T
A
V
A
V
F
E
P
G
Q
G
G
P
L
V
V
N
I
G
D
-
S
P
-
L
Y
R
I
R
D
G
H
-
M
E
Q
L
T
D
-----------------------
D
H
---------------------------
S
-----------------------------------
V
A
G
E
L
V
R
M
GEIT
R
H
E
A
R
W
HPQRHLLTRA
L
G
--------
I
G
P
H
--
I
G
P
D
V
F
G
I
D
C
-
G
P
G
D
R
L
L
I
S
S
D
G
L
F
A
A
A
D
--------
E
A
L
I
V
D
A
A
T
S
P
----
D
P
Q
V
A
V
R
R
L
V
E
V
-
A
N
----
D
A
G
G
S
D
N
T
T
V
V
V
I
D
L
G
30
HHSearch
67.82
14%
-77
- C1 -
2PK0
2
?
A:
[20-246]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
Q
D
F
I
N
Q
F
E
N
K
A
G
V
P
L
-
I
I
L
A
D
G
M
G
G
-
H
-
R
A
G
N
I
A
S
E
M
T
V
T
-
D
L
G
S
D
W
A
E
T
------
D
F
S
E
L
S
E
I
R
D
W
M
L
V
----
S
I
E
----
T
E
N
R
K
I
Y
E
L
G
Q
S
D
D
Y
----
K
G
M
G
T
T
I
E
A
V
A
I
V
---
G
D
N
I
I
F
A
H
V
G
D
-
S
R
-
I
G
I
V
R
Q
G
E
-
Y
H
L
L
T
S
-----------------------
D
H
S
L
V
N
E
L
V
K
A
GQLT
E
E
E
A
A
S
HPQKNIIT
Q
-----------------------------------
S
---------------------------
I
G
--------
Q
A
N
P
--
V
E
P
D
L
G
V
H
L
L
-
E
E
G
D
Y
L
V
V
N
S
D
G
L
T
N
M
L
--------
S
N
A
D
I
A
T
V
L
T
Q
E
---
K
T
L
D
D
K
N
Q
D
L
I
T
L
-
A
N
H
----
R
G
G
L
D
N
I
T
V
A
L
V
Y
V
E
45
Fugue
64.56
15%
25
- C1 -
3ES2
-
?
A:
[145-392]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
A
S
L
N
L
L
Q
E
D
Q
N
A
G
R
Q
V
Q
---
M
N
M
L
P
V
T
P
W
S
I
E
G
L
E
F
S
H
R
I
I
P
S
L
---
Y
L
S
G
D
F
V
D
Y
F
R
V
D
-
E
R
R
V
A
F
Y
L
A
D
V
S
G
H
-
G
-
A
S
S
A
F
V
T
V
L
L
K
F
M
T
T
-
R
L
L
Y
E
S
------
R
R
F
---
K
----
P
S
E
----
V
L
A
----
H
I
N
R
G
L
I
N
T
K
L
G
K
H
V
T
M
L
G
G
V
I
D
L
E
K
N
S
L
T
Y
S
I
--------
G
G
H
L
P
-
L
--
P
V
L
F
V
E
G
Q
-
A
G
Y
L
E
G
-----------------------
R
--------------------------------------------------------------------------------------------
V
G
--------
L
F
D
D
--
A
T
Y
---
D
D
R
V
M
E
L
P
P
S
L
S
L
F
S
D
G
I
L
D
V
G
A
T
--------------------
L
K
E
K
E
A
S
L
P
E
Q
V
A
A
-
A
G
G
T
L
D
G
L
R
Q
V
D
D
I
A
L
L
V
L
S
R
N
38
HHSearch
61.58
9%
-60
- C1 -
3BY9
3
?
A:
[12-259]
---------------------------------------------
H
Q
S
Q
L
D
R
F
S
S
H
I
V
A
T
L
D
K
Y
A
H
I
P
H
L
I
S
K
D
K
E
L
V
D
A
L
L
S
A
Q
N
S
A
Q
I
D
I
T
N
R
Y
L
E
Q
V
N
E
V
I
Q
A
A
D
T
Y
L
I
D
R
-
F
G
N
T
I
A
S
S
N
W
N
L
D
----
R
S
F
I
G
R
N
F
A
W
R
P
Y
F
Y
L
S
I
A
G
Q
K
S
Q
Y
--
F
A
L
G
S
T
S
G
Q
R
G
Y
Y
Y
A
Y
P
V
I
Y
--
A
A
E
I
L
G
V
I
V
V
K
M
D
L
S
A
I
E
Q
G
W
Q
N
----
K
S
S
Y
----
F
V
A
T
D
D
H
Q
V
V
F
M
S
S
Q
P
A
-
W
-
L
F
H
S
V
A
D
L
S
-------
P
A
Q
L
N
D
I
R
Q
S
Q
Q
Y
L
D
S
P
I
P
S
L
G
W
Q
-
G
D
L
Q
A
---
E
Q
S
---
E
W
R
K
P
EKHWL
Q
D
D
Y
I
V
S
S
R
P
L
P
E
L
A
L
T
I
R
V
L
S
P
K
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
61.22
20%
-67
- C1 -
3RNR
8
?
A:
[9-211]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
A
Y
-
C
V
V
V
D
G
M
G
G
-
M
-
I
R
G
D
E
A
A
Q
R
A
L
S
-
A
S
V
G
V
L
D
A
--------
G
G
---
S
----
P
L
D
----
A
V
L
----
A
A
Q
A
A
V
H
R
W
A
S
Q
G
G
I
---
L
G
R
T
G
A
T
M
A
V
A
A
V
N
L
-
R
D
G
T
L
E
W
A
S
V
G
D
-
C
R
-
V
Y
L
F
K
G
G
R
-
L
S
R
L
S
L
DHN
V
S
S
E
M
V
L
L
GRGPVPGPAGEM
I
T
---------------------------
S
-----------------------------------
F
---------------------------
I
G
--------
I
E
N
L
T
E
I
S
T
S
E
A
P
L
P
L
-
E
A
G
E
G
V
L
V
V
S
D
-----
L
--------
H
E
D
R
I
A
M
A
L
S
R
G
-
S
--
D
A
R
G
I
L
Q
E
V
E
A
-------
Q
G
R
P
Y
Q
D
N
A
T
L
A
L
V
I
L
-
26
HHSearch
60.68
15%
-59
- C1 -
3T91
3
SP2E_BACSU
A:
[14-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
A
K
G
G
G
---
L
V
S
G
D
S
Y
S
M
M
E
L
G
A
R
K
Y
A
-
A
A
I
S
D
G
-------
R
A
H
F
E
S
N
E
T
I
K
-
L
L
E
K
I
L
E
S
--------
G
I
---
D
----
E
K
I
----
A
I
K
----
T
I
N
S
I
L
S
L
R
------------
I
Y
S
T
L
D
L
S
I
I
D
L
-
Q
D
A
S
C
K
F
L
K
V
G
S
-
T
P
-
S
F
I
K
R
G
D
Q
-
V
M
K
V
Q
A
-----------------------
S
------------------------------------------------------------------------------------------------------
I
I
N
E
--
F
D
V
E
V
V
S
E
Q
L
-
K
A
G
D
L
L
I
M
M
S
D
G
I
F
E
G
P
K
H
---
V
E
N
H
D
L
W
M
K
R
K
M
K
G
L
-
K
T
N
D
P
Q
E
I
A
D
L
L
M
E
E
-
V
I
R
T
R
S
-
G
Q
I
E
D
D
M
T
V
V
V
V
R
I
D
22
HHSearch
57.22
15%
24
- C1 -
3EQ2
-
?
A:
[150-390]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
L
Q
E
D
Q
N
A
G
R
Q
V
Q
M
N
M
-
L
-
P
V
T
P
W
S
-
I
E
G
L
E
F
S
H
R
I
I
--------
S
G
D
F
V
D
Y
F
R
V
D
E
R
R
V
A
-
F
Y
L
A
D
V
S
G
H
-
G
-
A
S
S
A
F
V
T
V
L
L
K
F
-
M
T
T
R
L
L
Y
E
S
RRNGTL
P
E
F
---
K
----
P
S
E
----
V
L
A
----
H
I
N
R
G
L
I
N
T
K
L
---------
G
K
H
V
T
M
L
G
G
V
I
D
L
-
E
K
N
S
L
T
Y
S
I
G
G
H
L
P
L
-
P
V
L
F
V
E
G
Q
-
A
G
Y
L
E
G
-----------------------
R
----------------------------------------------------------------
P
---------------------------
V
G
--------
L
F
D
D
--
A
--
D
D
R
V
M
E
L
-
P
P
S
F
S
L
S
L
F
S
D
G
I
L
D
------
T
L
K
E
K
E
A
S
L
P
E
Q
V
A
A
A
-
G
-------
L
D
G
L
R
Q
V
--
F
G
L
A
N
L
A
E
--
D
D
I
A
L
L
V
L
S
--
41
HHSearch
54.07
16%
-67
- C1 -
3C8C
2
?
A:
[90-229]
--------------------------------------------------------------------------------------------------------------------------------------------
R
V
R
P
W
Y
K
D
A
K
N
A
G
K
L
V
I
T
A
P
Y
A
D
S
A
S
G
E
I
L
V
S
V
A
T
P
V
K
D
SA
T
G
Q
F
L
G
S
I
F
Y
D
V
S
L
A
E
L
A
E
L
V
N
E
V
K
L
F
D
A
G
Y
----
V
F
I
V
S
E
D
G
T
T
I
A
H
P
K
K
E
-
F
-
N
G
K
P
M
-----------
S
E
F
L
G
------
E
---
S
K
I
-----
N
-
V
-
D
-
T
-----
H
---
Q
V
I
I
N
-----
G
K
P
Y
A
V
S
F
S
D
V
E
G
E
D
W
Y
V
G
V
V
I
D
E
E
I
A
Y
A
A
L
D
E
L
R
R
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
52.88
12%
-70
- C1 -
3LIB
1
?
A:
[123-270]
---------------------------------------------------------------------------------------------------------------------------------------------
S
S
D
Y
Y
Q
L
P
K
A
T
E
K
D
V
L
T
E
P
Y
F
Y
E
--
G
V
F
M
V
S
Y
V
S
P
I
M
K
--
E
G
E
F
A
G
I
G
G
V
D
V
S
L
E
Y
V
D
E
V
V
S
K
V
R
T
F
D
T
G
Y
----
A
F
M
V
S
N
S
G
V
I
L
S
H
P
T
H
K
D
W
-
I
G
K
K
D
L
----------
Y
D
F
G
G
-
E
-
E
L
E
K
A
S
-
R
D
I
---
K
N
G
-
I
-
G
G
H
---
L
E
T
---
A
D
P
T
T
-----
G
K
T
V
I
L
F
Y
E
P
V
E
T
G
D
F
A
F
V
L
V
V
P
K
E
E
M
L
A
G
V
A
D
L
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
52.62
15%
-75
- C1 -
3LI9
1
?
A:
[124-271]
---------------------------------------------------------------------------------------------------------------------------------------------
S
S
D
Y
Y
Q
L
P
K
T
T
G
K
D
T
L
T
E
P
Y
F
Y
E
--
G
I
F
M
V
S
Y
D
S
P
I
F
K
--
N
G
E
F
A
G
I
A
G
V
D
V
P
L
E
Y
V
D
D
V
A
S
S
I
R
T
F
D
T
G
Y
----
A
F
M
V
S
N
T
G
I
F
L
S
H
P
T
Q
K
-
N
W
I
G
E
K
S
-
L
---------
S
D
F
D
V
-----
E
E
I
K
-
N
A
A
S
D
I
R
E
G
-
I
-
G
G
H
---
V
E
I
---
K
D
P
I
T
-----
G
K
T
V
I
M
F
Y
E
P
V
K
T
G
D
F
S
F
V
L
V
V
P
K
E
E
M
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
52.29
30%
3
- C2 -
3NYF
2
DAUA_PSEAE
A:
[231-310]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
F
A
P
P
-
P
G
I
D
CHDW
P
M
L
V
S
L
D
E
S
F
Y
L
K
P
D
A
G
-
M
-
L
L
G
S
P
A
N
A
D
P
V
E
A
H
D
V
-----
Q
P
E
Q
L
D
I
A
T
-
G
M
Y
L
I
E
E
A
T
-
T
-
L
T
I
RRP
E
H
T
---
W
A
G
L
R
-----
S
F
V
A
D
G
D
L
V
A
G
Y
A
A
N
A
E
G
F
F
W
V
A
A
Q
G
G
Y
G
I
Q
T
S
A
A
M
G
E
A
S
A
A
L
I
R
H
Q
P
L
P
A
H
L
R
E
H
G
L
D
E
A
M
L
S
P
R
R
L
S
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
51.68
30%
12
- C2 -
4H1B
3
DAUA_PSEAE
A:
[230-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
F
A
P
P
-
P
G
I
D
CHDW
P
M
L
V
S
L
D
E
S
F
Y
L
K
P
D
A
G
-
M
-
L
L
G
S
P
A
N
A
D
P
V
E
A
H
D
V
-----
Q
P
E
Q
L
D
I
A
T
-
G
M
Y
L
I
E
E
A
T
-
T
-
L
T
I
RRP
E
H
T
---
W
A
G
L
R
-----
S
F
V
A
D
G
D
L
V
A
G
Y
A
A
N
A
E
G
F
F
W
V
A
A
Q
G
G
Y
G
I
Q
T
S
A
A
M
G
E
A
S
A
A
L
I
R
H
Q
P
L
P
A
H
L
R
E
H
G
L
D
E
A
M
L
S
P
R
R
L
S
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
51.58
30%
11
- C2 -
3NYC
1
DAUA_PSEAE
A:
[231-310]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
F
A
P
P
-
P
G
I
D
CHDW
P
M
L
V
S
L
D
E
S
F
Y
L
K
P
D
A
G
-
M
-
L
L
G
S
P
A
N
A
D
P
V
E
A
H
D
V
-----
Q
P
E
Q
L
D
I
A
T
-
G
M
Y
L
I
E
E
A
T
-
T
-
L
T
I
R
R
P
E
H
T
---
W
A
G
L
R
-----
S
F
V
A
D
G
D
L
V
A
G
Y
A
A
N
A
E
G
F
F
W
V
A
A
Q
G
G
Y
G
I
Q
T
S
A
A
M
G
E
A
S
A
A
L
I
R
H
Q
P
L
P
A
H
L
R
E
H
G
L
D
E
A
M
L
S
P
R
R
L
S
P
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