@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0182: (2015-12-25 )
MSVSSASLAGKVAFVQGGSRGIGAAIVRRLAAEGASVAFTYVSSADKSRALAAELEGAGASILALHADSADAAALVAAVDEAAARFGRIDILVNNAAVLALGSVEELPLADFERTLAINVRSVFVATQAAVKHMGDGGRVISIGSTNAERMPFAGGATYAMSKSALVGLTKGLARDLGPRGITVNNVQPGPVDTDMNPDDGDFAEALKGLMALPRYARSEEIASFVAYLAGPEAAYITGASLTIDGGFSA
Atome Classification :
(24 SA)
.........10........20........30.......---------.40..-......50....--....60.......---.70........80........90........100.......110.......120.......130--...---..--.---..140.......150........160.......170.......180.......190....---------------.--------..---200------....-----------...210-----..-.....220.......230-........240.......250
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSVSSASLA
G
K
V
A
F
V
QGGSR
G
I
G
A
A
I
V
R
R
L
A
AEGA
S
V
A
---------
F
T
Y
VS-SADKS
R
A
L
A
A
E
L--EGAG
A
S
I
L
A
L
HAD---SA
D
A
A
A
L
V
A
A
V
D
E
A
A
A
RFG
R
I
D
I
L
VNN
A
A
V
L
A
LGSVEELP
L
A
D
F
E
R
T
L
A
I
N
V
R
S
V
F
V
A
T
Q
A
A
V
---
K
HM---GD--G---
G
R
V
I
S
IGSTNAER-MPFAGGA
T
Y
AM
S
K
S
A
L
V
G
L
T
K
G
L
A
R
DLGPRG
I
T
VNNVQPGPVDTDM---------------N--------PD---DG
D
------
F
A
E
A
-----------
L
K
G
L
M
A-----LP-RYA
R
S
E
E
I
A
S
F
V
A
Y
LA-G-PE
A
A
Y
I
TG
A
S
L
T
IDGGFSA
1
PsiBlast_PDB
93.28
54%
-97
- C1 -
3V2G
2
?
A:
[25-271]
---
T
S
I
S
L
A
G
K
T
A
F
V
T
G
G
S
R
G
I
G
A
A
I
A
K
R
L
A
L
E
G
A
A
V
A
---------
L
T
Y
V
N
-
A
A
E
R
A
Q
A
V
V
S
E
I
--
E
Q
A
G
G
R
A
V
A
I
R
A
D
---
N
R
D
A
E
A
I
E
Q
A
I
R
E
T
V
E
A
L
G
G
L
D
I
L
V
N
S
A
G
I
W
H
S
A
P
L
E
E
T
T
V
A
D
F
D
E
V
M
A
V
N
F
R
A
P
F
V
A
I
R
S
A
S
---
R
H
L
---
G
D
--
G
---
G
R
I
I
T
I
G
S
N
L
A
E
L
-
V
P
W
P
G
I
S
L
Y
S
A
S
K
A
A
L
A
G
L
T
K
G
L
A
R
D
L
G
P
R
G
I
T
V
N
I
V
H
P
G
S
T
D
T
D
M
---------------
N
--------
P
A
---
D
G
D
------
H
A
E
A
-----------
Q
R
E
R
I
A
-----
T
G
-
S
Y
G
E
P
Q
D
I
A
G
L
V
A
W
L
A
-
G
-
P
Q
G
K
F
V
T
G
A
S
L
T
I
D
G
G
A
N
A
33
PsiBlast_CBE
81.74
41%
-99
- C1 -
4DMM
1
?
B:
[26-266]
-------
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
---------
V
N
Y
A
S
-
S
A
G
A
A
D
E
V
V
A
A
I
--
A
A
A
G
G
E
A
F
A
V
K
A
D
VSQ
E
S
E
V
E
A
L
F
A
A
V
I
E
---
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
---
K
I
M
LK-
Q
R
--
S
---
G
R
I
I
N
I
A
S
V
V
G
E
--
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
---------------
T
--------
S
----------------------------
L
L
E
V
I
P
-----
L
G
-
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
32
PsiBlast_CBE
81.74
41%
-100
- C1 -
4DMM
1
?
C:
[26-266]
-------
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
---------
V
N
Y
A
S
-
S
A
G
A
A
D
E
V
V
A
A
I
--
A
A
A
G
G
E
A
F
A
V
K
A
D
VSQ
E
S
E
V
E
A
L
F
A
A
V
I
E
---
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
---
K
I
M
LK-
Q
R
--
S
---
G
R
I
I
N
I
A
S
V
V
G
E
--
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
----------------------------------------
E
K
-----------
L
L
E
V
I
P
-----
L
G
-
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
11
PsiBlast_PDB
80.66
41%
-89
- C1 -
4DMM
1
?
A:
[26-266]
-------
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
---------
V
N
Y
A
S
-
S
A
G
A
A
D
E
V
V
A
A
I
--
A
A
A
G
G
E
A
F
A
V
K
A
D
VSQ
E
S
E
V
E
A
L
F
A
A
V
I
E
---
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
---
K
I
M
L
K
-
Q
R
--
S
---
G
R
I
I
N
I
A
S
V
V
G
E
--
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
---------------
T
--------
S
E
---
L
A
--------
A
E
K
-----------
L
L
E
V
I
P
-----
L
G
-
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
114
HHSearch
80.45
42%
-92
- C1 -
3WTB
-
?
A:
[3-245]
------
H
M
T
H
R
V
A
L
I
T
G
G
S
R
G
I
G
A
A
I
A
L
K
L
A
Q
D
G
F
D
I
A
---------
I
T
Y
A
R
-
N
E
K
A
A
Q
K
V
V
S
E
V
--
E
A
L
G
R
K
A
V
A
V
Q
A
D
---
G
G
S
T
D
G
N
I
A
A
I
T
K
T
H
E
A
F
G
R
L
D
A
L
V
C
N
A
G
I
Y
P
Y
G
P
I
A
Q
M
T
V
T
Q
I
E
E
V
L
N
L
N
L
R
A
A
M
V
E
T
V
E
A
L
---
K
Y
M
---
K
T
--
G
---
G
R
L
I
Y
I
G
S
A
F
G
E
R
-
A
P
F
P
G
I
S
L
Y
A
A
T
K
A
G
L
I
G
F
T
K
G
V
A
R
D
L
G
P
Q
G
I
T
A
N
V
V
E
P
G
P
I
A
T
D
L
---------------
N
--------
P
E
---
D
G
A
------
A
A
A
V
-----------
I
R
K
F
T
A
-----
T
E
-
S
Y
G
K
V
N
D
I
A
R
T
V
S
F
L
A
-
S
-
P
D
A
S
Y
I
T
G
A
S
I
L
V
D
G
G
L
V
A
3
PsiBlast_PDB
80.13
42%
-92
- C1 -
3WTB
-
?
A:
[3-246]
------
H
M
T
H
R
V
A
L
I
T
G
G
S
R
G
I
G
A
A
I
A
L
K
L
A
Q
D
G
F
D
I
A
---------
I
T
Y
A
R
-
N
E
K
A
A
Q
K
V
V
S
E
V
--
E
A
L
G
R
K
A
V
A
V
Q
A
D
---
G
G
S
T
D
G
N
I
A
A
I
T
K
T
H
E
A
F
G
R
L
D
A
L
V
C
N
A
G
I
Y
P
Y
G
P
I
A
Q
M
T
V
T
Q
I
E
E
V
L
N
L
N
L
R
A
A
M
V
E
T
V
E
A
L
---
K
Y
M
---
K
T
--
G
---
G
R
L
I
Y
I
G
S
A
F
G
E
R
-
A
P
F
P
G
I
S
L
Y
A
A
T
K
A
G
L
I
G
F
T
K
G
V
A
R
D
L
G
P
Q
G
I
T
A
N
V
V
E
P
G
P
I
A
T
D
L
---------------
N
--------
P
E
---
D
G
A
------
A
A
A
V
-----------
I
R
K
F
T
A
-----
T
E
-
S
Y
G
K
V
N
D
I
A
R
T
V
S
F
L
A
-
S
-
P
D
A
S
Y
I
T
G
A
S
I
L
V
D
G
G
L
V
A
4
PsiBlast_PDB
79.90
37%
-92
- C1 -
4JRO
-
?
A:
[25-269]
-----
M
T
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
---------
F
N
Y
N
G
-
S
P
E
A
A
E
E
T
A
K
L
V
--
A
E
H
G
V
E
V
E
A
M
K
A
N
---
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
---
R
T
M
---
M
K
Q
R
A
---
G
K
I
I
N
M
A
S
V
-
V
G
L
-
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
---------------
T
--------
D
K
L--
D
E
K
------
T
K
E
A
-----------
M
L
A
Q
I
P
-----
L
G
-
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
-
D
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
31
PsiBlast_CBE
79.40
41%
-101
- C1 -
4DMM
1
?
D:
[26-266]
-------
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
---------
V
N
Y
A
S
-
S
A
G
A
A
D
E
V
V
A
A
I
--
A
A
A
G
G
E
A
F
A
V
K
A
D
VSQ
E
S
E
V
E
A
L
F
A
A
V
I
E
---
R
W
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
---
K
I
M
LK-
Q
R
--
S
---
G
R
I
I
N
I
A
S
V
V
G
E
--
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
-------------------------------------------
K
-----------
L
L
E
V
I
P
-----
L
G
-
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
23
PsiBlast_CBE
79.40
37%
-92
- C1 -
4JRO
1
?
C:
[25-269]
-----
M
T
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
---------
F
N
Y
N
G
-
S
P
E
A
A
E
E
T
A
K
L
V
--
A
E
H
G
V
E
V
E
A
M
K
A
N
---
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
---
R
T
M
---
M
K
QR
A
---
G
K
I
I
N
M
A
S
V
-
V
G
L
-
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
---------------
T
--------
D
K
L--
D
E
K
------
T
K
E
A
-----------
M
L
A
Q
I
P
-----
L
G
-
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
-
D
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
22
PsiBlast_CBE
79.23
37%
-90
- C1 -
4JRO
1
?
D:
[25-269]
-----
M
T
L
Q
G
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
---------
F
N
Y
N
G
-
S
P
E
A
A
E
E
T
A
K
L
V
--
A
E
H
G
V
E
V
E
A
M
K
A
N
---
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
---
R
T
M
---
M
K
QR
A
---
G
K
I
I
N
M
A
S
V
-
V
G
L
-
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
---------------
T
-------------
D
E
K
------
T
K
E
A
-----------
M
L
A
Q
I
P
-----
L
G
-
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
-
D
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
86
PsiBlast_CBE
78.88
36%
-91
- C1 -
3OEC
1
?
D:
[44-312]
-------
L
Q
G
K
V
A
F
I
T
G
A
A
R
G
Q
G
R
T
H
A
V
R
L
A
Q
D
G
A
D
I
V
A
I
D
LCRQQN
L
D
Y
A
Q
G
S
P
E
E
L
K
E
T
V
R
L
V
--
E
E
Q
G
R
R
I
I
A
R
Q
A
D
---
V
R
D
L
A
S
L
Q
A
V
V
D
E
A
L
A
E
F
G
H
I
D
I
L
V
S
N
V
G
I
S
N
Q
G
E
V
V
S
L
T
D
Q
Q
W
S
D
I
L
Q
T
N
L
I
G
A
W
H
A
C
R
A
V
L
---
P
S
M
I
E
R
G
Q
--
G
---
G
S
V
I
F
V
S
S
T
V
G
L
R
G
A
P
--
G
Q
S
H
Y
A
A
S
K
H
G
V
Q
G
L
M
L
S
L
A
N
E
V
G
R
H
N
I
R
V
N
S
V
N
P
G
A
V
N
T
E
M
ALN
E
K
L
L
K
M
F
L
PHLE
N
--------
P
T
---
R
E
D
------
A
A
E
L
-----------
F
S
Q
L
T
L
-----
L
P
I
P
W
V
E
P
E
D
V
S
N
A
V
A
W
L
A
-
S
-
D
E
A
R
Y
I
H
G
A
A
I
P
V
D
G
G
Q
L
A
87
PsiBlast_CBE
78.40
36%
-92
- C1 -
3OEC
1
?
C:
[44-312]
-------
L
Q
G
K
V
A
F
I
T
G
A
A
R
G
Q
G
R
T
H
A
V
R
L
A
Q
D
G
A
D
I
V
A
I
D
LCRQN-
L
D
Y
A
Q
G
S
P
E
E
L
K
E
T
V
R
L
V
--
E
E
Q
G
R
R
I
I
A
R
Q
A
D
---
V
R
D
L
A
S
L
Q
A
V
V
D
E
A
L
A
E
F
G
H
I
D
I
L
V
S
N
V
G
I
S
N
Q
G
E
V
V
S
L
T
D
Q
Q
W
S
D
I
L
Q
T
N
L
I
G
A
W
H
A
C
R
A
V
L
---
P
S
M
I
E
R
G
Q
--
G
---
G
S
V
I
F
V
S
S
T
V
G
L
R
G
A
P
--
G
Q
S
H
Y
A
A
S
K
H
G
V
Q
G
L
M
L
S
L
A
N
E
V
G
R
H
N
I
R
V
N
S
V
N
P
G
A
V
N
T
E
M
ALN
E
K
L
L
K
M
F
L
PHLE
N
--------
P
T
---
R
E
D
------
A
A
E
L
-----------
F
S
Q
L
T
L
-----
L
P
I
P
W
V
E
P
E
D
V
S
N
A
V
A
W
L
A
-
S
-
D
E
A
R
Y
I
H
G
A
A
I
P
V
D
G
G
Q
L
A
15
PsiBlast_PDB
77.96
30%
-95
- C1 -
3QWI
6
?
A:
[16-268]
-------
L
D
G
K
V
A
L
V
T
G
S
G
R
G
I
G
A
A
V
A
V
H
L
G
R
L
G
A
K
V
V
---------
V
N
Y
A
N
-
S
T
K
D
A
E
K
V
V
S
E
I
--
K
A
L
G
S
D
A
I
A
I
K
A
D
---
I
R
Q
V
P
E
I
V
K
L
F
D
Q
A
V
A
H
F
G
H
L
D
I
A
V
S
N
S
G
V
V
S
F
G
H
L
K
D
V
T
E
E
E
F
D
R
V
F
S
L
N
T
R
G
Q
F
F
V
A
R
E
A
Y
---
R
H
L
---
T
E
--
G
---
G
R
I
V
L
T
S
S
N
T
S
K
D
-
F
S
V
P
K
H
S
L
Y
S
G
S
K
G
A
V
D
S
F
V
R
I
F
S
K
D
C
G
D
K
K
I
T
V
N
A
V
A
P
G
G
T
V
T
D
M
---------------
F
H
E
V
S
H
H
Y
I
P
N
---
G
T
S
------
Y
T
A
E
-----------
Q
R
Q
Q
M
A
A
H
ASP
L
H
-
R
N
G
W
P
Q
D
V
A
N
V
V
G
F
L
V
-
S
-
K
E
G
E
W
V
N
G
K
V
L
T
L
D
G
G
A
A
-
20
PsiBlast_PDB
77.56
30%
-92
- C1 -
4FJ2
2
?
A:
[16-268]
-------
L
D
G
K
V
A
L
V
T
G
S
G
R
G
I
G
A
A
V
A
V
H
L
G
R
L
G
A
K
V
V
---------
V
N
Y
A
N
-
S
T
K
D
A
E
K
V
V
S
E
I
--
K
A
L
G
S
D
A
I
A
I
K
A
D
---
I
R
Q
V
P
E
I
V
K
L
F
D
Q
A
V
A
H
F
G
H
L
D
I
A
V
S
N
S
G
V
V
S
F
G
H
L
K
D
V
T
E
E
E
F
D
R
V
F
S
L
N
T
R
G
Q
F
F
V
A
R
E
A
Y
---
R
H
L
---
T
E
--
G
---
G
R
I
V
L
T
S
S
N
T
S
K
D
-
F
S
V
P
K
H
S
L
Y
S
G
S
K
G
A
V
D
S
F
V
R
I
F
S
K
D
C
G
D
K
K
I
T
V
N
A
V
A
P
G
G
T
V
T
D
M
---------------
F
H
E
V
S
HHYI
P
N
---
G
T
S
------
Y
T
A
E
-----------
Q
R
Q
Q
M
A
A
H
ASP
L
H
-
R
N
G
W
P
Q
D
V
A
N
V
V
G
F
L
V
-
S
-
K
E
G
E
W
V
N
G
K
V
L
T
L
D
G
G
A
A
-
12
PsiBlast_PDB
77.50
37%
-101
- C1 -
4RZH
-
?
A:
[3-244]
------
A
L
T
A
Q
V
A
L
V
T
G
A
S
R
G
I
G
K
A
T
A
L
A
L
A
A
T
G
M
K
V
V
---------
V
N
Y
A
Q
-
S
S
T
A
A
D
A
V
V
A
E
I
--
I
A
N
G
G
E
A
I
A
V
Q
A
N
---
V
A
N
A
D
E
V
D
Q
L
I
K
T
T
L
D
K
F
S
R
I
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
L
E
D
W
Q
A
V
I
D
L
N
L
T
G
V
F
L
C
T
K
A
V
S
---
K
L
M
L
K
-
Q
K
--
S
---
G
R
I
I
N
I
T
S
V
-
A
G
M
-
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
F
T
K
T
V
A
K
E
L
A
S
R
G
V
T
V
N
A
V
A
P
G
F
I
A
--------------------------------------------
P
-----------
I
L
Q
F
I
P
-----
L
A
-
R
Y
G
Q
P
E
E
V
A
G
T
I
R
F
L
A
T
D
-
P
A
A
A
Y
I
T
G
Q
T
F
N
V
D
G
G
M
V
M
70
PsiBlast_CBE
77.16
37%
-85
- C1 -
1GEG
2
BUDC_KLEPN
C:
[3-253]
----------
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
---------
I
A
D
Y
N
-
D
A
-
T
A
K
A
V
A
S
E
I
--
N
Q
A
G
G
H
A
V
A
V
K
V
D
---
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
G
G
F
D
V
I
V
N
N
A
G
V
A
P
S
T
P
I
E
S
I
T
P
E
I
V
D
K
V
Y
N
I
N
V
K
G
V
I
W
G
I
Q
A
A
V
EAF
K
K
E
---
G
H
--
G
---
G
K
I
I
N
-
A
C
S
Q
A
G
H
-
V
G
N
P
E
L
A
V
Y
S
S
S
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
I
V
K
T
P
M
---------------
W
--------
A
E
I--
D
R
Q
------
V
S
E
A
AGKPLGYGTAE
F
A
K
R
I
T
-----
L
G
-
R
L
S
E
P
E
D
V
A
A
C
V
S
Y
L
A
-
S
-
P
D
S
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
V
F
82
PsiBlast_CBE
77.13
37%
-94
- C1 -
3WYE
1
?
B:
[3-252]
----------
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
---------
I
A
D
Y
N
-
D
A
-
T
A
K
A
V
A
S
E
I
--
N
Q
A
G
G
H
A
V
A
V
K
V
D
---
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
G
G
F
D
V
I
V
N
N
A
G
I
A
Q
I
K
P
L
L
E
V
T
E
E
D
L
K
Q
I
Y
S
V
N
V
F
S
V
F
F
G
I
Q
A
A
V
E
A
F
K
K
E
---
G
H
--
G
---
G
K
I
I
N
A
A
S
I
A
A
I
Q
--
G
F
P
I
L
S
A
Y
S
T
T
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
I
V
G
T
G
M
W
E
Q
I
D
A
E
L
S
K----------------------------------------------
S
I
A
-----
L
G
-
R
P
S
V
P
E
D
V
A
G
L
V
S
F
L
A
-
S
-
P
D
S
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
V
F
14
PsiBlast_PDB
76.51
30%
-92
- C1 -
3QWF
4
?
A:
[16-268]
-------
L
D
G
K
V
A
L
V
T
G
S
G
R
G
I
G
A
A
V
A
V
H
L
G
R
L
G
A
K
V
V
---------
V
N
Y
A
N
-
S
T
K
D
A
E
K
V
V
S
E
I
--
K
A
L
G
S
D
A
I
A
I
K
A
D
---
I
R
Q
V
P
E
I
V
K
L
F
D
Q
A
V
A
H
F
G
H
L
D
I
A
V
S
N
S
G
V
V
S
F
G
H
L
K
D
V
T
E
E
E
F
D
R
V
F
S
L
N
T
R
G
Q
F
F
V
A
R
E
A
Y
---
R
H
L
---
T
E
--
G
---
G
R
I
V
L
T
S
S
N
T
S
K
D
-
F
S
V
P
K
H
S
L
Y
S
G
S
K
G
A
V
D
S
F
V
R
I
F
S
K
D
C
G
D
K
K
I
T
V
N
A
V
A
P
G
G
T
V
T
D
M
---------------
F
H
E
V
SHHYI
P
N
---
G
T
S
------
Y
T
A
E
-----------
Q
R
Q
Q
M
A
AHASP
L
H
-
R
N
G
W
P
Q
D
V
A
N
V
V
G
F
L
V
-
S
-
K
E
G
E
W
V
N
G
K
V
L
T
L
D
G
G
A
A
-
37
PsiBlast_CBE
76.49
31%
-92
- C1 -
1RWB
1
DHG_BACME
A:
[5-251]
-------
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
---------
V
N
Y
R
S
-
K
E
D
E
A
N
S
V
L
E
E
I
--
K
K
V
G
G
E
A
I
A
V
K
G
D
---
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
---
K
Y
F
---
V
E
--
N
DIK
G
T
V
I
N
M
S
S
V
H
-
E
K
-
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
---------------
N
--------
A
E
K
F
A
D
P
E
------
Q
R
A
D
-----------
V
E
S
M
I
P
-----
M
G
-
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
-
S
-
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
36
PsiBlast_CBE
76.41
31%
-93
- C1 -
1RWB
1
DHG_BACME
B:
[5-251]
-------
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
---------
V
N
Y
R
S
-
K
E
D
E
A
N
S
V
L
E
E
I
--
K
K
V
G
G
E
A
I
A
V
K
G
D
---
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
---
K
Y
F
---
V
E
--
N
DIK
G
T
V
I
N
M
S
S
V
H
-
E
K
-
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
---------------
N
--------
A
E
KFA
D
P
E
------
Q
R
A
D
-----------
V
E
S
M
I
P
-----
M
G
-
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
-
S
-
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
21
PsiBlast_CBE
75.17
49%
-103
- C1 -
4PCV
3
?
B:
[5-233]
------
A
F
T
G
K
T
V
L
I
L
G
G
S
R
G
I
G
A
A
I
V
R
R
F
V
T
D
G
A
N
V
R
---------
F
T
Y
A
G
-
S
K
D
A
A
K
R
L
A
Q
E
-----
T
G
A
T
--
A
V
F
T
D
---
S
A
D
R
D
A
V
I
D
V
V
R
K
S
G
A
----
L
D
I
L
V
V
N
A
G
------
A
L
E
L
N
A
D
D
I
D
R
L
F
K
I
N
I
H
A
P
Y
H
A
S
V
E
A
A
---
R
Q
M
---
P
E
--
G
---
G
R
I
L
I
I
G
S
V
N
G
--------
M
A
A
Y
A
A
S
K
S
A
L
Q
G
M
A
R
G
L
A
R
D
F
G
P
R
G
I
T
I
N
V
V
Q
P
-------------------------------------------------------------------------------
E
E
V
A
G
M
V
A
W
L
A
-
G
-
P
E
A
S
F
V
T
G
A
M
H
T
I
------
2
PsiBlast_PDB
72.58
49%
-101
- C1 -
4PCV
4
?
A:
[5-233]
------
A
F
T
G
K
T
V
L
I
L
G
G
S
R
G
I
G
A
A
I
V
R
R
F
V
T
D
G
A
N
V
R
---------
F
T
Y
A
G
-
S
K
D
A
A
K
R
L
A
Q
E
-----
T
G
A
T
--
A
V
F
T
D
---
S
A
D
R
D
A
V
I
D
V
V
R
K
S
G
A
----
L
D
I
L
V
V
N
A
G
I
---------
N
A
D
D
I
D
R
L
F
K
I
N
I
H
A
P
Y
H
A
S
V
E
A
A
---
R
Q
M
---
P
E
--
G
---
G
R
I
L
I
I
G
S
V
----------
M
A
A
Y
A
A
S
K
S
A
L
Q
G
M
A
R
G
L
A
R
D
F
G
P
R
G
I
T
I
N
V
V
Q
P
G
P
--------------------------------------------------------------------------
G
Q
P
E
E
V
A
G
M
V
A
W
L
A
-
G
-
P
E
A
S
F
V
T
G
A
M
H
T
I
------
56
PsiBlast_CBE
66.65
38%
-87
- C1 -
3RRO
11
FABG_VIBCH
A:
[9-248]
------
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
---------
G
T
-
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
GD
N
G
K
G
M
A
L
N
V
T
N
P
E
---
S
I
E
A
V
-
L
K
A
I
T
D
E
----
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
---
R
G
M
M
K
-
K
R
--
Q
---
G
R
I
I
N
V
G
S
V
-
V
G
T
-
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
---------------
T
--------
K
A
---
L
N
D
E
Q
R
T
A
T
L
A
Q
V
-----------
P
A
G
R
L
G
-----
D
P
-
R
-----
E
I
A
S
A
V
A
F
L
A
-
S
-
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
55
PsiBlast_CBE
66.50
38%
-88
- C1 -
3RRO
13
FABG_VIBCH
B:
[9-248]
------
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
---------
G
T
-
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
GD
N
G
K
G
M
A
L
N
V
T
N
P
E
---
S
I
E
A
V
-
L
K
A
I
T
D
E
----
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
---
R
G
M
MK-
K
R
--
Q
---
G
R
I
I
N
V
G
S
V
-
V
G
T
-
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
---------------
T
--------
K
A
---
L
N
D
EQRTAT
L
A
Q
V
-----------
P
A
G
R
L
G
-----
D
P
-
R
-----
E
I
A
S
A
V
A
F
L
A
-
S
-
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M