@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0374: (2016-01-02 )
MIRFEQVGKRYPNGHVGLHEVSFRVHRGEILFVTGHSGAGKSTLLRLILAMERPTSGKLLLGGQDLGRITTAQIPFLRRQIGVVFQNHQLLTDRTVADNIALPLQILGMPKPEIAKRVASALERVNLKEKGEALPSDLSTGQQQRVGIARAIVHQPALLLADEPTGNLDPRLASEIMGVFEDINRLGTTVLIASHDLALIARMRHRMLTLQRGRIIADREDEA
Atome Classification :
(41 SA)
---....--.....10..---.---.---.-...20........30........40........50........60.....-------...70---------..---...-...-.80.....--...90........100.-.....-.-.110.......120.......130-..-......140.......150.......160.......170.......180.-.-.-....190.......200.......210.......220.---------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MI
R
F
--
E
Q
V
G
K
RYPN---G---H---V-G
L
H
E
V
S
F
R
V
HR
G
E
I
L
F
V
TGHSGA
G
K
S
T
L
L
R
L
I
L
A
MERPTSG
K
L
L
LGGQDL-------GR
I
T
----------
T
A
---
Q
I
P
-
F
L
R
-
R
Q
I
G
V
VFQ--NHQLLTDRTVADNI-
A
L
-
P
L
Q
IL-G-MP
K
P
E
I
A
K
R
V
A
S
A
L
E
RV
N
L
K
E
KG--EA-LPSDLST
G
Q
Q
Q
R
V
G
I
A
R
A
I
VHQP
A
L
L
L
ADEPTGNL
D
P
R
L
A
S
E
I
M
G
V
F
E
D
I
-
N
-R-LG
T
T
V
L
I
AS
H
D
L
A
L
I
A
R
M
R
H
R
M
L
T
L
QR
G
R
I
IADREDEA---------------------------------------------------------------------------------------------------------------------------
102
HHSearch
91.13
40%
-117
* C1 *
3TUI
1
METN_ECOLI
C:
[24-249]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
GTR
T
---
I
---
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
-
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
122
Fugue
90.98
40%
-120
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--H
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
TRT
I
---
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
-
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
VFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV-----------
2
PsiBlast_PDB
89.37
40%
-124
- C1 -
3TUI
1
METN_ECOLI
C:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
89.01
36%
-116
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[4-220]
---
I
L
R
A
--
E
N
I
-
K
K
V
I
R
---
G
---
Y
---
E
-
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
-------
D
Y
T
N
----------
E
K
---
E
L
S
-
L
L
R
N
R
K
L
G
F
V
F
Q
--
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
-
P
M
L
K
M
-
G
-
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
L
--
S
R
-
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
-
E
-
G
G
T
S
I
V
M
V
T
H
E
R
E
L
-
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
V
----------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
88.37
36%
-121
- C1 -
2PCJ
1
LOLD_AQUAE
B:
[4-220]
---
I
L
R
A
--
E
N
I
-
K
K
V
I
R
---
G
---
Y
---
E
-
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
-------
D
Y
T
N
----------
E
K
---
E
L
S
-
L
L
R
N
R
K
L
G
F
V
F
Q
--
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
-
P
M
L
K
M
-
G
-
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
L
--
S
R
-
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
-
E
-
G
G
T
S
I
V
M
V
T
H
E
R
E
L
-
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
V
----------------------------------------------------------------------------------------------------------------------------
125
Fugue
88.34
35%
-115
- C1 -
1Z47
1
?
A:
[11-355]
GSM
T
I
E
F
--
V
G
V
E
K
I
Y
P
G
---
G
---
A
---
R
-
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
-------
T
D
L
P
----------
P
Q
---
K
-------
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
-
G
L
R
E
K
-
R
-
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
A
--
N
R
-
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
-
E
-
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
EKPGT
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
6
PsiBlast_PDB
88.33
36%
-117
- C1 -
2PCL
12
LOLD_AQUAE
A:
[4-220]
---
I
L
R
A
--
E
N
I
-
K
K
V
I
R
---
G
---
Y
---
E
-
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
-------
D
Y
T
N
----------
E
K
---
E
L
S
-
L
L
R
N
R
K
L
G
F
V
F
Q
--
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
-
P
M
L
K
M
-
G
-
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
L
--
S
R
-
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
-
E
-
G
G
T
S
I
V
M
V
T
H
E
R
E
L
-
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
V
----------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
88.26
40%
-125
- C1 -
3TUI
1
METN_ECOLI
H:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
88.22
40%
-129
- C1 -
3TUZ
1
METN_ECOLI
C:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
118
HHSearch
87.28
36%
-114
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[4-223]
---
I
L
R
A
--
E
N
I
K
K
V
I
R
----
G
---
Y
---
E
-
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
-------
D
Y
T
N
----------
E
K
---
E
L
S
L
L
R
N
-
R
K
L
G
F
V
F
Q
--
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
-
P
M
L
K
M
-
G
-
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
L
--
S
R
-
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
-
E
-
G
G
T
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
V
----------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.20
41%
-120
- C1 -
3DHW
-
METN_ECOLI
C:
[1-220]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.72
40%
-121
- C1 -
3TUZ
1
METN_ECOLI
G:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
86.65
40%
-122
- C1 -
3TUI
1
METN_ECOLI
D:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
86.24
40%
-122
- C1 -
3TUZ
1
METN_ECOLI
D:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
86.03
40%
-122
- C1 -
3TUI
1
METN_ECOLI
G:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
85.85
40%
-125
- C1 -
3TUZ
1
METN_ECOLI
H:
[24-243]
---
M
I
K
L
--
S
N
I
T
K
V
F
H
Q
---
G
---
T
RTI
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
----------
E
S
---
E
L
T
-
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
D
-
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
---------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
84.16
36%
-126
- C1 -
1Z47
1
?
B:
[15-224]
----
I
E
F
--
V
G
V
E
K
I
Y
P
G
---
G
---
A
---
R
-
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
----------
R
V
T
---------------
D
L
P
-
P
Q
K
-
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
-
G
L
R
E
K
-
R
-
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
A
--
N
R
-
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
-
E
-
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
---------------------------------------------------------------------------------------------------------------------------
101
HHSearch
84.07
36%
-116
- C1 -
1Z47
1
?
A:
[15-231]
----
I
E
F
--
V
G
V
E
K
I
Y
P
G
---
G
---
A
---
R
-
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
-------
T
D
L
P
-------------------
P
Q
K
-
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
-
G
L
R
E
K
-
R
-
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
A
--
N
R
-
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
-
H
-
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
---------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
82.97
36%
-125
- C1 -
1Z47
1
?
A:
[15-224]
----
I
E
F
--
V
G
V
E
K
I
Y
P
G
---
G
---
A
---
R
-
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
----------
R
V
T
---------------
D
L
P
-
P
Q
K
-
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
-
G
L
R
E
K
-
R
-
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
A
--
N
R
-
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
-
E
-
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
---------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
82.72
36%
-116
- C1 -
1OXS
18
?
C:
[1-220]
---
M
V
R
I
IV
K
N
V
S
K
V
F
K
K
---
G
---
K
---
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
-------
A
S
N
G
----------
K
L
---
I
V
P
-
P
E
D
-
R
K
I
G
M
V
F
Q
--
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
-
P
L
T
N
M
-
K
-
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
V
L
--
N
H
-
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
-
R
-
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
81.84
33%
-121
- C1 -
4YMU
2
?
J:
[1-217]
---
M
I
F
V
--
N
D
V
Y
K
N
F
G
S
---
L
---
E
---
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
NN-----
G
K
V
N
----------
I
N
---
K
V
----
R
-
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
K
-
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
--
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
---------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
81.29
33%
-124
- C1 -
4YMU
2
?
A:
[1-217]
---
M
I
F
V
--
N
D
V
Y
K
N
F
G
S
---
L
---
E
---
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
NN-----
G
K
V
N
----------
I
N
---
K
V
----
R
-
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
K
-
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
--
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
---------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
79.62
33%
-121
- C1 -
4YMV
1
?
A:
[1-217]
---
M
I
F
V
--
N
D
V
Y
K
N
F
G
S
---
L
---
E
---
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
NN-----
G
K
V
N
----------
I
N
---
K
V
----
R
-
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
K
-
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
--
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
---------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
77.32
32%
-115
- C1 -
2OLK
1
?
D:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
120
HHSearch
76.21
33%
-118
- C1 -
1B0U
4
HISP_SALTY
A:
[7-238]
----
L
H
V
--
I
D
L
H
K
R
Y
G
----
G
---
H
---
E
-
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
-------
N
L
V
R
D
KDGQLKVAD
K
N
---
Q
L
R
-
L
L
R
-
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
-
M
E
-
A
P
I
Q
V
L
G
-
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q-
G
K
-
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
-
A
-
E
-
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
---------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
75.94
32%
-116
- C1 -
2OLJ
4
?
A:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
75.42
32%
-114
- C1 -
2OLK
1
?
C:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
75.37
32%
-112
- C1 -
2OLK
2
?
B:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
74.75
32%
-114
- C1 -
2OLK
1
?
A:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
74.53
32%
-113
- C1 -
3C41
3
?
K:
[3-223]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
74.52
32%
-112
- C1 -
2Q0H
4
?
A:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
74.19
32%
-116
- C1 -
3C4J
4
?
B:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
116
HHSearch
73.57
33%
-113
- C1 -
2OLJ
4
?
A:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
----
S
---
L
---
E
-
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-------
K
A
K
D
----------
T
----
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
-
A
P
M
K
V
-
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
73.27
32%
-112
- C1 -
3C4J
3
?
A:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
72.53
32%
-110
- C1 -
3C41
3
?
J:
[3-223]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
72.43
32%
-112
- C1 -
2OLJ
3
?
B:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
72.41
32%
-115
- C1 -
2Q0H
4
?
B:
[24-244]
---
M
I
D
V
--
H
Q
L
K
K
S
F
G
S
---
L
---
E
---
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
----------
D
T
---
N
L
N
-
K
V
R
-
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
R
-
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
--
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------
107
HHSearch
72.11
31%
-107
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[4-224]
---
A
L
H
I
--
G
H
L
S
K
S
F
Q
----
N
---
T
---
P
-
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
-------
F
S
K
N
----------
T
----
N
L
P
-
V
R
E
-
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
-
A
Y
-
G
L
G
N
G
-
K
-
G
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
A
--
G
R
-
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
-
L
R
A
-
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
---------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
71.85
34%
-119
- C1 -
1B0U
4
HISP_SALTY
A:
[14-231]
-------------
K
R
Y
-
G
---
G
---
H
---
E
-
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KD
G
Q
L
K
----------
V
A
D
K
N
Q
L
R
-
L
L
R
-
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
-
P
I
Q
V
L
-
G
-
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
--
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
-
A
-
E
-
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
---------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
71.25
33%
-118
- C1 -
4U00
3
?
A:
[4-219]
---
I
I
R
I
--
R
N
L
H
K
W
F
G
P
---
L
---
H
---
V
--
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
--
L
-------
S
V
K
D
----------
D
R
---
A
L
R
-
E
I
R
-
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
R
-
R
-
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
--
R
K
-
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
---------------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
66.07
33%
-122
- C1 -
4HLU
3
ECFA2_THEMA
B:
[24-221]
-------------------------------
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
E
----------
R
K
K
----------
G
Y
---
E
I
----
R
-
R
N
I
G
I
A
F
Q
YP
E
D
Q
F
F
A
E
R
-
V
F
D
E
V
-
A
F
-
A
V
K
N
F
---
Y
P
D
R
D
P
V
P
L
V
K
K
A
M
E
F
V
G
L
D
F
D
S
FK
D
R
-
V
P
F
F
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
E
K
W
-
K
-
T
-
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
R
M
E
---------------------------------------------------------------------------------------------------------------------------