@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0425: (2016-01-04 )
MQRTPAMRVLVPALLVAISALSGCGKSEAPPPAQTPEVGIVTLEAQTVTLNTELPGRTNAFRIAEVRPQVNGIILKRLFKEGSDVKAGQQLYQIDPATYEADYQSAQANLASTQEQAQRYKLLVADQAVSKQQYADANAAYLQSKAAVEQARINLRYTKVLSPISGRIGRSAVTEGALVTNGQANAMATVQQLDPIYVDVTQPSTALLRLRRELASGQLERAGDNAAKVSLKLEDGSQYPLEGRLEFSEVSVDEGTGSVTIRAVFPNPNNELLPGMFVHAQLQEGVKQKAILAPQQGVTRDLKGQATALVVNAQNKVELRVIKADRVIGDKWLVTEGLNAGDKIITEGLQFVQPGVEVKTVPAKNVASAQKADAAPAKTDSKG
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQRTP
A
M
R
V
L
V
P
A
L
L
V
A
I
S
A
L
SGCGKSEAPPPAQTP
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
NTELPGRTN
A
F
R
I
A
E
VRPQ
V
N
G
I
I
L
K
R
L
F
KEGSDVKAG
Q
Q
L
Y
Q
IDPATYEA
D
Y
Q
S
A
QANL
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
VADQAV
S
K
Q
QYAD
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
VLSPISGRIG
R
S
AVTE
G
A
L
VTNGQA
N
A
M
A
T
VQQLD
P
I
Y
V
D
VTQ
P
S
T
A
L
L
R
L
R
R
E
L
ASG
Q
L
E
RAGDN
A
A
K
V
S
L
K
LEDGSQYPLEG
R
L
E
F
S
E
V
S
VDEGTG
S
V
T
I
R
A
V
FPNPNNELL
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
KAILAPQQGVTRDLKGQ
A
T
A
L
V
V
NAQ
N
K
V
E
L
R
V
I
K
ADRVIGD
K
W
L
V
TEGLNA
G
D
K
I
I
T
E
G
L
Q
F
VQPGV
E
V
K
TVPAKNVASAQKADAAPAKTDSKG
33
PsiBlast_CBE
99.07
99%
-95
- C7 -
2V4D
3
MEXA_PSEAE
M:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
41
PsiBlast_CBE
98.01
99%
-92
- C7 -
2V4D
2
MEXA_PSEAE
E:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
37
PsiBlast_CBE
97.95
99%
-93
- C7 -
2V4D
2
MEXA_PSEAE
I:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
38
PsiBlast_CBE
97.81
99%
-94
- C7 -
2V4D
2
MEXA_PSEAE
H:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
34
PsiBlast_CBE
97.71
99%
-93
- C7 -
2V4D
3
MEXA_PSEAE
L:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
39
PsiBlast_CBE
97.60
99%
-95
- C7 -
2V4D
2
MEXA_PSEAE
G:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
43
PsiBlast_CBE
97.59
99%
-95
- C7 -
2V4D
3
MEXA_PSEAE
C:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
40
PsiBlast_CBE
97.55
99%
-95
- C7 -
2V4D
3
MEXA_PSEAE
F:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
36
PsiBlast_CBE
97.40
99%
-94
- C7 -
2V4D
1
MEXA_PSEAE
J:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
44
PsiBlast_CBE
97.10
99%
-93
- C7 -
2V4D
4
MEXA_PSEAE
B:
[13-339]
-----------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
Q
A
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
---------------------
23
PsiBlast_CBE
84.40
100%
-88
- C7 -
1T5E
2
MEXA_PSEAE
K:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
70
Fugue
84.31
100%
-88
- C7 -
1T5E
1
MEXA_PSEAE
A:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
84.27
100%
-88
- C7 -
1T5E
1
MEXA_PSEAE
E:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
84.25
100%
-87
- C7 -
1T5E
2
MEXA_PSEAE
J:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
84.21
100%
-88
- C7 -
1T5E
1
MEXA_PSEAE
A:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
84.18
100%
-89
- C7 -
1T5E
1
MEXA_PSEAE
M:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
83.81
100%
-86
- C7 -
1T5E
2
MEXA_PSEAE
C:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
83.81
100%
-86
- C7 -
1T5E
2
MEXA_PSEAE
I:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
83.64
100%
-88
- C7 -
1T5E
2
MEXA_PSEAE
H:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
83.58
100%
-88
- C7 -
1T5E
2
MEXA_PSEAE
G:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
N
A
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
L
E
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------