@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0771: (2016-01-18 )
MTDMHDDIPAGSRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGEVQAVYVDTPGLHKSGEKALNRYMNRTASAALKDVDVVIFVVDRTRWTEEDQMVLERVQYVSCPVLIAVNKTDRIEEKADLLPHLEWLTQQLPKAEVVPISAQHGTNLDVLEKLVAERLPESEHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQEGRILHIHALILVEREGQKKIIIGDKGERIKSIGQNARKDMEVLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
Atome Classification :
(24 SA)
--.........10....--....20........30........40........50-.......-.-60........70.---.....--.-.80...-.....90...---.....100.-...-...110.....-..120.--........130...---.--...140.......-150..-.....160.......170.....---..180.......190........200.......210.......220.....-..---230--....-....240.......250.......260.......270.......280.......290.......300...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MTDMHDDIPAGSRC
G
--
Y
V
A
I
VGRPNV
G
K
S
T
L
L
N
H
I
LGQ
K
L
AITSRKPQTTRH-
N
M
L
G
I
KT-E-G
E
V
Q
A
V
Y
VDTPGL---HK
S
G
E
--
K
-
A
L
N
R
Y
M
-
N
R
T
A
SAALKD---
V
D
V
V
I
F
V
V
D-RTR-WT
E
E
D
Q
M
V
L
E
R
-
V
Q
Y--V--SC
P
V
L
I
A
VNKT
D
R
I
---
E
--
E
K
A
D
L
L
P
H
L
E
W
L
T
-
Q
QLPK-A
E
V
V
P
I
SAQHGT
N
L
D
V
L
E
K
L
V
A
E
---RLPESEHFFPEDQI-T
D
R
S
S
R
F
L
A
A
E
L
V
R
E
K
I
M
R
Q
LGAEL
P
Y
Q
I
T
V
E
I
E
E
F
-
K
Q---EG---
R
I
L
H
-
I
H
A
L
I
L
V
EREG
Q
K
K
I
I
IGDK
G
E
R
I
K
S
I
G
Q
N
A
R
K
D
M
E
V
L
FDS
K
V
M
L
N
L
W
V
K
V
KGGWS
D
D
E
R
A
L
R
SLGYGDL
3
PsiBlast_PDB
93.33
61%
-118
- C2 -
3IEU
7
ERA_ECOLI
A:
[6-296]
-------------
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
----
22
PsiBlast_CBE
92.83
61%
-119
- C2 -
1EGA
2
ERA_ECOLI
B:
[6-296]
-------------
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
----
21
PsiBlast_CBE
92.68
61%
-118
- C2 -
3IEU
9
ERA_ECOLI
B:
[6-296]
-------------
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
----
1
PsiBlast_PDB
91.82
61%
-119
- C2 -
1EGA
3
ERA_ECOLI
A:
[6-295]
-------------
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-----
54
HHSearch
91.59
59%
-121
- C2 -
1EGA
3
ERA_ECOLI
A:
[4-295]
-----------
D
K
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
R
-
A
-
I
N
R
-
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
G
T
R
--
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
R--
G
G
Y
D
-
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-----
7
PsiBlast_PDB
90.59
42%
-112
- C2 -
3IEV
4
ERA_AQUAE
A:
[9-307]
--------------
K
V
G
--
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
-
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
---
Y
E
P
K
K
--
S
D
V
L
G
H
S
M
-
V
E
I
A
K
Q
S
L
E
E
---
A
D
V
I
L
F
M
I
D
-
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
---
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
-
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
---
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
-
K
P
GDA
N
P
---
N
M
L
V
-
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
-
5
PsiBlast_PDB
89.91
42%
-112
- C2 -
3R9W
8
ERA_AQUAE
A:
[8-306]
--------------
K
V
G
--
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
-
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
---
Y
E
P
K
K
--
S
D
V
L
G
H
S
M
-
V
E
I
A
K
Q
S
L
E
E
---
A
D
V
I
L
F
M
I
D
-
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
---
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
-
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
---
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
-
K
P
G
DA
N
P
---
N
M
L
V
-
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
-
6
PsiBlast_PDB
88.98
42%
-108
- C2 -
3R9X
4
ERA_AQUAE
A:
[8-306]
--------------
K
V
G
--
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
-
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
---
Y
E
P
K
K
--
S
D
V
L
G
H
S
M
-
V
E
I
A
K
Q
S
L
E
E
---
A
D
V
I
L
F
M
I
D
-
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
---
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
-
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
---
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
-
K
P
GDA
N
P
---
N
M
L
V
-
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
-
56
HHSearch
87.69
42%
-105
- C2 -
3IEV
4
ERA_AQUAE
A:
[7-307]
------------
H
M
K
V
G
--
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
-
R
V
L
G
V
K
N
-
I
P
N
E
A
Q
I
I
F
L
D
T
P
G
I
---
Y
E
P
K
K
SD
V
-
L
G
H
-
S
M
-
V
E
I
A
K
Q
S
L
E
E
---
A
D
V
I
L
F
M
I
D
A
T
E
G
-
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
---
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
K
K
H
P
E
L
-
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
---
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
-
K
P
---
G
D
ANP
N
M
L
V
-
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
-
8
PsiBlast_PDB
84.55
42%
-111
- C2 -
1WF3
4
ERA_THET8
A:
[5-296]
-------------
T
Y
S
G
--
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
-
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
L
---
H
K
P
M
D
----
A
L
G
E
F
M
-
D
Q
E
V
Y
E
A
L
A
D
---
V
N
A
V
V
W
V
V
D
L
R
H
P
-
P
T
P
E
D
E
L
V
A
R
A
-
L
K
P
--
L
VG
K
V
P
I
L
L
V
G
N
K
L
D
A
A
---
K
--
Y
P
E
E
A
M
K
A
Y
H
E
L
----
L
P
E
-
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
---
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
E
R
---
E
N
---
G
V
L
Y
-
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
-
55
HHSearch
84.27
41%
-102
- C2 -
1WF3
4
ERA_THET8
A:
[3-298]
-----------
E
K
T
Y
S
G
--
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
-
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
L
---
H
K
P
M
D
--
A
-
L
G
E
-
F
M
-
D
Q
E
V
Y
E
A
L
A
D
---
V
N
A
V
V
W
V
V
D
L
R
H
P
-
P
T
P
E
D
E
L
V
A
R
A
-
L
K
P
LV
G
--
K
V
P
I
L
L
V
G
N
K
L
D
A
A
---
K
--
Y
P
E
E
A
M
---
K
A
Y
H
-
E
L
L
P
E
-
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
---
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
-
A
E
---
R
E
N--
G
V
L
Y
-
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
-
44
Fugue
70.32
57%
-128
- C2 -
1EGA
3
ERA_ECOLI
A:
[4-182]
-----------
D
K
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
-
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
----
20
PsiBlast_PDB
60.70
27%
-110
- C2 -
3PQC
2
ENGB_THEMA
A:
[24-193]
----------------
G
--
E
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
R
K
I
A
F
V
S
K
T
P
G
K
T
R
S
I
N
F
Y
L
V
N
S
------
K
Y
Y
F
V
D
L
P
G
Y
---
G
Y
A
K
V
--
S
-
K
K
E
R
M
L
W
K
R
L
V
E
D
Y
F
K
N
RWS
L
Q
M
V
F
L
L
V
D
G
R
I
P
-
P
Q
D
S
D
L
M
M
V
E
W
-
M
K
S
--
L
--
N
I
P
F
T
I
V
L
T
K
M
D
K
V
---
K
MS
E
R
A
K
K
L
E
E
H
R
K
V
F
-
S
K
Y
G
E
-
Y
T
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
---
L
L
K
--------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
58.70
23%
-106
- C2 -
1PUI
4
ENGB_ECOLI
A:
[11-198]
F
V
M
S
A
P
D
I
R
H
L
P
S
D
T
G
I
--
E
V
A
F
A
G
R
S
N
A
G
K
S
S
A
L
N
T
L
T
N
Q
Q
-----------
L
I
-
N
L
F
E
V
A
D
-
G
-----
K
R
L
V
D
L
P
G
Y
GEM
K
R
K
W
Q
--
R
-
A
L
G
E
Y
L
-
E
K
R
Q
S
--------
L
Q
G
L
V
V
L
M
D
I
R
H
P
-
L
K
D
L
D
Q
Q
M
I
E
W
-
A
V
D
--
S
--
N
I
A
V
L
V
L
L
T
K
A
D
K
L
A
S
G
A
--
R
K
A
Q
L
N
M
V
R
E
A
V
L
-
A
F
N
G
D
-
V
Q
V
E
T
F
S
S
L
K
K
Q
G
V
D
K
L
R
Q
K
L
D
T
---
W
F
S
--------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
58.30
34%
-129
- C2 -
4DCS
1
DER_BACSU
A:
[23-191]
-----------------K
P
V
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
------------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----------
P
-
F
L
A
Q
-
I
-
R
Q
Q
A
E
I
A
M
D
E
---
A
D
V
I
I
F
M
V
N
G
R
E
G
-
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
---------
M
R
A
N
I
-----
Y
D
F
-
Y
S
L
G
F
-
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
K
N
I
P
E
T
K
Y
N
E
E
V
I
Q
F
-
C
L
I
G
R
P
N
V
G
K
S
S
L
V
N
A
M
L
G
E
E
R
V
I
V
S
N
D
A
V
D
T
S
F
T
Y
-
N
Q
---
Q
E
---
F
V
I
V
-
D
T
A
G
M
R
K
K
G
K
V
Y
E
T
T
E
K
Y
S
V
L
R
A
L
K
A
I
D
R
S
E
V
V
A
V
V
L
D
G
E
E
G
I
I
E
Q
D
K
R
I
A
G
Y
A
H
E
A
G
K
A
V
V
I
V
V
N
K
W
D
A
2
PsiBlast_PDB
58.24
61%
116
- C- -
1X1L
-
ERA_THET8
X:
[6-295]
-------------
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-----
4
PsiBlast_PDB
58.14
61%
119
- C- -
1X18
2
ERA_THET8
X:
[3-292]
-------------
S
Y
C
G
--
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
-
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
---
H
M
E
E
K
--
R
-
A
I
N
R
L
M
-
N
K
A
A
S
S
S
I
G
D
---
V
E
L
V
I
F
V
V
E
-
G
T
R
-
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
---
Q
--
E
K
A
D
L
L
P
H
L
Q
F
L
A
-
S
Q
M
N
F
-
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
---
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
-
V
S
---
N
E
---
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-----
10
PsiBlast_PDB
57.68
34%
-138
- C2 -
4DCU
1
DER_BACSU
A:
[23-191]
-----------------K
P
V
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
------------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----------
P
-
F
L
A
Q
-
I
-
R
Q
Q
A
E
I
A
M
D
E
---
A
D
V
I
I
F
M
V
N
G
R
E
G
-
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
-------------------
Y
D
F
-
Y
S
L
G
F
-
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
FK
N
I
P
E
T
K
Y
N
E
E
V
I
Q
F
-
C
L
I
G
R
P
N
V
G
K
S
S
L
V
N
A
M
L
G
E
E
R
V
I
V
S
N
D
A
V
D
T
S
F
T
Y
-
N
Q
---
Q
E
---
F
V
I
V
-
D
T
A
G
M
R
K
K
G
K
V
Y
E
T
T
E
K
Y
S
V
L
R
A
L
K
A
I
D
R
S
E
V
V
A
V
V
L
D
G
E
E
G
I
I
E
Q
D
K
R
I
A
G
Y
A
H
E
A
G
K
A
V
V
I
V
V
N
K
W
D
A
12
PsiBlast_PDB
57.53
34%
-96
- C2 -
4KYU
6
DER_BACSU
A:
[6-163]
--------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
----------
R
D
-
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
I
---
D
I
G
D
E
--
P
-
F
L
A
Q
-
I
-
R
Q
Q
A
E
I
A
M
D
E
---
A
D
V
I
I
F
M
V
N
G
R
E
G
-
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
N
T
---
E
--
M
R
A
N
I
-----
Y
D
F
-
Y
S
L
G
F
-
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
---
H
F
---------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
57.29
34%
-138
- C2 -
4DCV
-
DER_BACSU
A:
[23-191]
-----------------K
P
V
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
------------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----------
P
-
F
L
A
Q
-
I
-
R
Q
Q
A
E
I
A
M
D
E
---
A
D
V
I
I
F
M
V
N
G
R
E
G
-
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
-------------------
Y
D
F
-
Y
S
L
G
F
-
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
FK
N
I
P
E
T
K
Y
N
E
E
V
I
Q
F
-
C
L
I
G
R
P
N
V
G
K
S
S
L
V
N
A
M
L
G
E
E
R
V
I
V
S
N
D
A
V
D
T
S
F
T
Y
-
N
Q
---
Q
E
---
F
V
I
V
-
D
T
A
G
M
R
K
K
G
K
V
Y
E
T
T
E
K
Y
S
V
L
R
A
L
K
A
I
D
R
S
E
V
V
A
V
V
L
D
G
E
E
G
I
I
E
Q
D
K
R
I
A
G
Y
A
H
E
A
G
K
A
V
V
I
V
V
N
K
W
D
A
14
PsiBlast_PDB
56.75
33%
-89
- C2 -
2DYK
1
?
A:
[4-161]
--------------------
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
-
L
K
E
G
V
V
E
-
T
-
D
R
G
R
F
L
L
V
D
T
G
G
L
---
W
-
S
G
D
--
K
--
W
E
K
K
I
-
Q
E
K
V
D
R
A
L
E
D
---
A
E
V
V
L
F
A
V
D
G
R
A
E
-
L
T
Q
A
D
Y
E
V
A
E
Y
-
L
R
R
--
K
--
G
K
P
V
I
L
V
A
T
K
V
D
D
P
---
K
--
H
E
L
Y
L
G
P
-----
L
-
Y
G
L
G
F
-
G
D
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
---
R
L
P
--------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
56.39
33%
-93
- C2 -
2DYK
2
?
B:
[4-161]
--------------------
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
-
L
K
E
G
V
V
E
-
T
-
D
R
G
R
F
L
L
V
D
T
G
G
L
---
W
-
S
G
D
--
K
--
W
E
K
K
I
-
Q
E
K
V
D
R
A
L
E
D
---
A
E
V
V
L
F
A
V
D
G
R
A
E
-
L
T
Q
A
D
Y
E
V
A
E
Y
-
L
R
R
--
K
--
G
K
P
V
I
L
V
A
T
K
V
D
D
P
---
K
--
H
E
L
Y
L
G
P
-----
L
-
Y
G
L
G
F
-
G
D
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
---
R
L
P
--------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
56.08
34%
-112
- C2 -
4KYU
5
DER_BACSU
B:
[6-163]
--------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
------------------
I
Y
S
S
A
E
-
W
--
N
Y
D
F
N
L
I
D
T
G
G
I
---
D
I
G
D
E
--
P
-
F
L
A
Q
-
I
-
R
Q
Q
A
E
I
A
M
D
E
---
A
D
V
I
I
F
M
V
N
G
R
E
G
-
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
N
T
---
E
--
M
R
A
N
I
-----
Y
D
F
-
Y
S
L
G
F
-
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
---
H
F
---------------------------------------------------------------------------------------------------------------------------------------
68
HHSearch
54.71
32%
-91
* C2 *
2DYK
1
?
A:
[2-160]
----------------
H
--
K
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
-
L
K
E
G
V
V
E
-
T
-
D
R
G
R
F
L
L
V
D
T
G
G
L
---
W
S
G
D
K
--
W
--
E
K
-
K
I
-
Q
E
K
V
D
R
A
L
E
D
---
A
E
V
V
L
F
A
V
D
G
R
A
E
-
L
T
Q
A
D
Y
E
V
A
E
Y
-
L
R
R
--
K
--
G
K
P
V
I
L
V
A
T
K
V
D
D
P
---
K
--
H
E
L
Y
-
L
G
--
P
L
Y
G
---
L
G
F
-
G
D
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
---
R
L
P
--------------------------------------------------------------------------------------------------------------------------------------