@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0775: (2016-01-18 )
MSESDRLFAQPQQRVADFVFNEDVVRVFPDMIKRSVPGYPTIVENIGVLGAQFAQPNSVLYDLGCSLGAVTQSLRRHVRNDGCRVIGVDNSHAMIERCSEYLHAQDAMYQELLPVELIEADILALDLQPTSLVAMNFTLQFVAPDQRLGLLRRIRQALLPGGALILSEKLRFADAQEHALLTDLHIAFKRANGYSELEIAQKRSALENVMLPDTFEEHRERLLAAGFSRVSQWFQCLNFASMIALP
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30...---.....40........50........60........70........80....-....90........100........110..--.....120....--.--..--130-------......-..140--..--..-..-.150........160....------------...170.......180------.---.------...-..----190...----...----.-----200---..-------.......210.......220.......230....-...240....----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------MSES
D
R
L
F
A
Q
P
Q
Q
R
V
A
D
F
VFN
E
D
V
V
R
V
F
P
D
M
I
K
R
---SVPGY
P
T
I
V
E
N
I
G
VLGAQFAQPNS
V
L
Y
DLGC
S
L
G
A
V
T
Q
S
L
R
R
H
V
RNDG
C
R
V
-
I
GVDN
S
H
A
M
I
E
R
C
S
E
-
Y
L
H
A
Q
D
A
M
Y
Q
E
LL
P
--
V
E
L
IEA
D
I
L
A
L
D--L--QP--
T
S
--------
L
V
A
M
N
F
-
T
L
Q
F
V--A
P
--
D
Q
-
R
L
-
G
L
-
L
R
R
I
R
Q
A
LLPG
G
A
L
I
L
------------
S
E
KLRFAD
A
Q
E
H
A
L
L
T
------
D
---
L
------
H
I
A
-
F
K----RANGY
S
----
E
L
E
----
I
-----
A
-----
Q
K
-------
R
S
A
L
ENVMLPD
T
F
E
E
H
R
E
R
L
L
A
A
G
F
S
R
V
S
Q
W
F
Q
C
-
L
N
F
A
S
M
IALP----------------------------------
3
PsiBlast_PDB
96.26
49%
-129
- C2 -
1IM8
2
CMOA_HAEIN
A:
[20-243]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
F
D
E
N
V
A
E
V
F
P
D
M
I
Q
R
---
S
V
P
G
Y
S
N
I
I
T
A
I
G
M
L
A
E
R
F
V
T
A
D
S
N
V
Y
D
L
G
C
S
R
G
A
A
T
L
S
A
R
R
N
I
N
Q
P
N
V
K
I
-
I
G
I
D
N
S
Q
P
M
V
E
R
C
R
Q
-
H
I
----
A
A
Y
H
S
E
I
P
--
V
E
I
L
C
N
D
I
R
H
V
E
--
I
--
K
N
--
A
S
--------
M
V
I
L
N
F
-
T
L
Q
F
L
--
P
P
--
E
D
-
R
I
-
A
L
-
L
T
K
I
Y
E
G
L
N
P
N
G
V
L
V
L
------------
S
E
K
F
R
F
E
D
T
K
I
N
H
L
L
I
------
D
---
L
------
H
H
Q
-
F
K
----
R
A
N
G
Y
S
----
E
L
E
----
V
-----
S
-----
Q
K
-------
R
T
A
L
E
N
V
M
R
T
D
S
I
E
T
H
K
V
R
L
K
N
V
G
F
S
Q
V
E
L
W
F
Q
C
-
F
N
F
G
S
M
I
A
V
K
----------------------------------
1
PsiBlast_PDB
96.12
53%
-125
- C2 -
4GEK
3
CMOA_ECOUT
A:
[32-255]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
T
F
D
E
R
V
A
E
V
F
P
D
M
I
Q
R
---
S
V
P
G
Y
S
N
I
I
S
M
I
G
M
L
A
E
R
F
V
Q
P
G
T
Q
V
Y
D
L
G
C
S
L
G
A
A
T
L
S
V
R
R
N
I
H
H
D
N
C
K
I
-
I
A
I
D
N
S
P
A
M
I
E
R
C
R
R
-
H
I
D
A
----
Y
K
A
P
T
P
--
V
D
V
I
E
G
D
I
R
D
I
A
--
I
--
E
N
--
A
S
--------
M
V
V
L
N
F
-
T
L
Q
F
L
--
E
P
--
S
E
-
R
Q
-
A
L
-
L
D
K
I
Y
Q
G
L
N
P
G
G
A
L
V
L
------------
S
E
K
F
S
F
E
D
A
K
V
G
E
L
L
F
------
N
---
M
------
H
H
D
-
F
K
----
R
A
N
G
Y
S
----
E
L
E
----
I
-----
S
-----
Q
K
-------
R
S
M
L
E
N
V
M
L
T
D
S
V
E
T
H
K
A
R
L
H
K
A
G
F
E
H
S
E
L
W
F
Q
C
-
F
N
F
G
S
L
V
A
L
K
----------------------------------
2
PsiBlast_PDB
96.03
54%
-126
- C2 -
4IWN
3
CMOA_ECOLI
A:
[1-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
F
D
E
R
V
A
E
V
F
P
D
M
I
Q
R
---
S
V
P
G
Y
S
N
I
I
S
M
I
G
M
L
A
E
R
F
V
Q
P
G
T
Q
V
Y
D
L
G
C
S
L
G
A
A
T
L
S
V
R
R
N
I
H
H
D
N
C
K
I
-
I
A
I
D
N
S
P
A
M
I
E
R
C
R
H
-
H
I
D
A
----
Y
K
A
P
T
P
--
V
D
V
I
E
G
D
I
R
D
I
A
--
I
--
E
N
--
A
S
--------
M
V
V
L
N
F
-
T
L
Q
F
L
--
E
P
--
S
E
-
R
Q
-
A
L
-
L
D
K
I
Y
Q
G
L
N
P
G
G
A
L
V
L
------------
S
E
K
F
S
F
E
D
A
K
V
G
E
L
L
F
------
N
---
M
------
H
H
D
-
F
K
----
R
A
N
G
Y
S
----
E
L
E
----
I
-----
S
-----
Q
K
-------
R
S
M
L
E
N
V
M
L
T
D
S
V
E
T
H
K
A
R
L
H
N
A
G
F
E
H
S
E
L
W
F
Q
C
-
F
N
F
G
S
L
V
A
L
K
----------------------------------
20
PsiBlast_CBE
95.57
53%
-126
- C2 -
4GEK
3
CMOA_ECOUT
G:
[29-255]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
D
W
T
F
D
E
R
V
A
E
V
F
P
D
M
I
Q
R
---
S
V
P
G
Y
S
N
I
I
S
M
I
G
M
L
A
E
R
F
V
Q
P
G
T
Q
V
Y
D
L
G
C
S
L
G
A
A
T
L
S
V
R
R
N
I
H
H
D
N
C
K
I
-
I
A
I
D
N
S
P
A
M
I
E
R
C
R
R
-
H
I
D
A
----
Y
K
A
P
T
P
--
V
D
V
I
E
G
D
I
R
D
I
A
--
I
--
E
N
--
A
S
--------
M
V
V
L
N
F
-
T
L
Q
F
L
--
E
P
--
S
E
-
R
Q
-
A
L
-
L
D
K
I
Y
Q
G
L
N
P
G
G
A
L
V
L
------------
S
E
K
F
S
F
E
D
A
K
V
G
E
L
L
F
------
N
---
M
------
H
H
D
-
F
K
----
R
A
N
G
Y
S
----
E
L
E
----
I
-----
S
-----
Q
K
-------
R
S
M
L
E
N
V
M
L
T
D
S
V
E
T
H
K
A
R
L
H
K
A
G
F
E
H
S
E
L
W
F
Q
C
-
F
N
F
G
S
L
V
A
L
K
----------------------------------
21
PsiBlast_CBE
94.83
54%
-123
- C2 -
4IWN
3
CMOA_ECOLI
B:
[2-223]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
E
R
V
A
E
V
F
P
D
M
I
Q
R
---
S
V
P
G
Y
S
N
I
I
S
M
I
G
M
L
A
E
R
F
V
Q
P
G
T
Q
V
Y
D
L
G
C
S
L
G
A
A
T
L
S
V
R
R
N
I
H
H
D
N
C
K
I
-
I
A
I
D
N
S
P
A
M
I
E
R
C
R
H
-
H
I
D
A
----
Y
K
A
P
T
P
--
V
D
V
I
E
G
D
I
R
D
I
A
--
I
--
E
N
--
A
S
--------
M
V
V
L
N
F
-
T
L
Q
F
L
--
E
P
--
S
E
-
R
Q
-
A
L
-
L
D
K
I
Y
Q
G
L
N
P
G
G
A
L
V
L
------------
S
E
K
F
S
F
E
D
A
K
V
G
E
L
L
F
------
N
---
M
------
H
H
D
-
F
K
----
R
A
N
G
Y
S
----
E
L
E
----
I
-----
S
-----
Q
K
-------
R
S
M
L
E
N
V
M
L
T
D
S
V
E
T
H
K
A
R
L
H
N
A
G
F
E
H
S
E
L
W
F
Q
C
-
F
N
F
G
S
L
V
A
L
K
----------------------------------
22
HHSearch
66.48
19%
-108
- C2 -
3DTN
2
?
A:
[8-224]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
F
D
A
V
S
G
K
Y
D
E
Q
R
R
K
---
F
I
P
C
F
D
D
F
Y
G
V
S
V
S
I
A
S
V
-
D
T
E
N
P
D
I
L
D
L
G
A
G
T
G
L
L
S
A
F
L
M
E
K
Y
--
P
E
A
T
F
-
T
L
V
D
M
S
E
K
M
L
E
I
A
K
N
-
R
F
R
G
-------
N
L
K
--
V
K
Y
I
E
A
D
Y
S
K
Y
D
--
F
E-
E
K
--
Y
D
--------
M
V
V
S
A
L
-
S
I
H
H
L
--
E
D
--
E
D
-
K
K
-
E
L
-
Y
K
R
S
Y
S
I
L
K
E
S
G
I
F
I
N
------------
A
D
L
V
H
G
E
T
A
F
I
E
N
L
N
K
------
T
---
I
------
W
R
Q
-
Y
V
----
E
N
S
G
L
T
----
E
E
E
----
I
-----------
A
A
-------
G
Y
----
L
D
K
D
I
E
M
N
Q
Q
L
N
W
L
K
E
A
G
F
R
D
V
S
C
I
Y
K
Y
-
Y
Q
F
A
V
M
F
G
R
K
----------------------------------
50
Fugue
60.84
20%
-104
- C2 -
3G07
1
MEPCE_HUMAN
A:
[34-288]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
R
L
R
V
L
K
P
E
W
F
-------------------------------------------
R
G
R
D
V
L
D
L
G
C
N
V
G
H
L
T
L
S
I
A
C
K
W
---
G
P
S
R
M
V
G
L
D
I
D
S
R
L
I
H
S
A
R
Q
-
N
I
V
P
L
D
G
A
D
T
S
V
F
P
NN
V
V
F
V
T
G
N
Y
V
L
D
R
--
D
--
D
L
--
V
E
A
Q
T
P
E
Y
DV
V
L
C
L
S
L
-
T
K
W
V
H
--
L
N
W
G
D
E
-
G
L
-
K
R
M
F
R
R
I
Y
R
H
L
R
P
G
G
I
L
V
L
------------
E
P
Q
P
W
S
S
Y
G
K
R
K
T
L
T
E
------
T
---
I
------
Y
K
N
-
Y
Y
----
R
----------------
I
-----
Q
-----
L
K
-------
P
E
Q
F
S
S
Y
L
T
S
P
D
----------
V
G
F
S
S
Y
E
L
V
R
P
V
-
Y
L
F
H
K
A
R
-------------------------------------
23
HHSearch
58.76
16%
-104
- C2 -
3DLC
4
?
A:
[7-212]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
D
K
K
G
A
K
N
M
D
E
I
S
K
T
L--
F
A
P
I
Y
P
I
I
A
E
N
I
I
N
R
F
---
G
I
T
A
G
T
C
I
D
I
G
S
G
P
G
A
L
S
I
A
L
A
K
Q
---
S
D
F
S
I
-
R
A
L
D
F
S
K
H
M
N
E
I
A
L
K
-
N
I
A
D
A
N
L
----
N
D
R
--
I
Q
I
V
Q
G
D
V
H
N
I
P
--
I
ED
N
Y
--
A
D
--------
L
I
V
S
R
G
-
S
V
F
F
W
--
E
D
--
V
---
A
-
T
A
-
F
R
E
I
Y
R
I
L
K
S
G
G
K
T
Y
I
------------
G
G
G
F
G
N
K
E
L
--
R
D
S
I
S
------
A
---
E
------
M
I
R
-
K
N
----
P
--
D
W
---------------------------------
K
E
F
N
R
K
N
I
S
Q
E
N
V
E
R
F
Q
N
V
L
D
E
I
G
I
S
S
Y
E
I
I
L
G
D
-
E
G
F
W
I
I
I
S
K
T
----------------------------------
29
HHSearch
56.29
16%
-101
- C2 -
3BXO
2
DESVI_STRVZ
A:
[4-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
E
V
D
H
A
D
V
Y
D
L
F
Y
L
G
---
R
G
K
D
Y
A
A
E
A
S
D
I
A
D
L
V
R
S
R
T
P
E
A
S
S
L
L
D
V
A
C
G
T
G
T
H
L
E
H
F
T
K
E
F
----
G
D
T
-
A
G
L
E
L
S
E
D
M
L
T
H
A
R
K
-
R
L
----------
P
D
--
A
T
L
H
Q
G
D
M
R
D
F
R
--
L
G-
R
K
--
F
S
--------
A
V
V
S
M
F
S
S
V
G
Y
L
--
K
T
T
-
E
E
-
L
G
-
A
A
-
V
A
S
F
A
E
H
L
E
P
G
G
V
V
V
V
------------
E
P
W
W
F
P
E
T
F
A
D
G
W
V
S
A
------
D
---
V
V
R
R
DG
R
T
V
A
-
R
V
S
H
S
V
R
E
G
N
A
T
----
R
M
E
V
H
F
T
V
-----
A
D
PG
K
G
V
R
-------
H
F
S
D
V
H
L
I
T
L
F
H
Q
A
E
Y
E
A
A
F
T
A
A
G
L
R
V
E
Y
L
E
G
G
P
-
S
G
R
G
L
F
V
G
V
P
----------------------------------
47
Fugue
55.59
15%
-105
- C2 -
3PX3
3
TYLM1_STRFR
A:
[10-249]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Q
A
D
Y
S
G
E
I
A
E
L
Y
D
L
V
H
Q
G
---
K
G
K
D
Y
H
R
E
A
A
D
L
A
A
L
V
R
R
H
S
P
K
A
A
S
L
L
D
V
A
C
G
T
G
M
H
L
R
H
L
A
D
S
----
F
G
T
V
-
E
G
L
E
L
S
A
D
M
L
A
I
A
R
R
-
R
N
P
----------
D
--
A
V
L
H
H
G
D
M
R
D
F
S
--
L
--
G
R
RF
S
A
--------
V
T
C
M
F
S
-
S
I
G
A
L
--
A
G
--
Q
A
-
E
L
D
A
A
-
L
E
R
F
A
A
H
V
L
P
D
G
V
V
V
V
E
P
W
W
FPENFTPG
Y
V
A
A
G
T
V
E
A
G
G
T
T
V
T
R
------
V
---
S
------
H
S
S
-
R
E
----
G
E
A
T
R
I
----
E
V
H
----
Y
-----
L
-----
V
A
G
PDR
G
I
T
H
H
E
E
S
H
R
I
T
L
F
T
R
E
Q
Y
E
R
A
F
T
A
A
G
L
S
V
E
F
M
P
G
G
P
-
S
G
R
G
L
F
T
G
L
P
G---------------------------------
36
HHSearch
54.78
20%
-99
- C2 -
2YQZ
1
?
A:
[7-196]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
A
Y
A
Y
D
R
L
R
A
H
---
P
P
E
V
A
G
Q
I
A
T
A
M
A
S
A
V
H
P
-
K
G
E
E
P
V
F
L
E
L
G
V
G
T
G
R
I
A
L
P
L
I
A
R
----
G
Y
R
Y
-
I
A
L
D
A
D
A
A
M
L
E
V
F
R
Q
-
K
I
A
G
V
------
D
R
K
--
V
Q
V
V
Q
A
D
A
R
A
I
P
--
L
PD
E
S
--
V
H
--------
G
V
I
V
V
H
-
L
W
H
L
V
--
P
D
--
W
---
P
-
K
V
-
L
A
E
A
I
R
V
L
K
P
G
G
A
L
L
E
------------
G
W
D
Q
A
E
A
S
P
E
W
T
--
L
Q
------
E
---
R
------
W
R
A
-
F
A
----
A
E
E
G
-----------------------------------
F
P
V
E
R
G
L
H
A
K
R
L
K
E
V
E
E
A
L
R
R
L
G
L
K
P
R
T
R
E
V
A
R
-
W
R
E
E
R
T
P
R
E
A
----------------------------------
4
PsiBlast_PDB
54.75
23%
-120
- C2 -
1VE3
1
?
A:
[4-139]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
Y
Y
R
V
F
P
T
Y
T
D
I
---
N
S
Q
E
Y
R
S
R
I
E
T
L
E
P
L
L
M
K
Y
M
K
K
R
G
K
V
L
D
L
A
C
G
V
G
G
F
S
F
L
L
E
D
Y
----
G
F
E
V
-
V
G
V
D
I
S
E
D
M
I
R
K
A
R
E
-
Y
A
K
S
R
E
S
------
N
--
V
E
F
I
V
G
D
A
R
K
L
S
--
F
--
E
D
--
K
T
--------
F
D
Y
V
I
F
-
I
D
S
I
V
HF
E
P
--
L
E
-
L
N
-
Q
V
-
F
K
E
V
R
R
V
L
K
P
S
G
K
F
I
M
------------
Y
F
T
D
L
R
E
L
L
P
R
L
K
E
I
S
------
K
---
V
------
I
P
D
-
Q
E
----
E
R
T
V
V
I
----
E
F
S
----
F
-----
R
-----
V
R
-------
F
N
V
W
G
K
T
G
V
E
L
L
A
K
L
Y
F
T
K
E
A
E
E
K
V
G
N
Y
S
Y
L
T
V
Y
-
N
P
K
-----------------------------------------
27
HHSearch
54.32
20%
-96
- C2 -
3OCJ
3
?
A:
[117-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
G
C
V
V
A
S
V
P
C
G
W
M
S
E
L
L
A
L
D
Y
S
A
-
C
P
G
V
Q
L
-
V
G
I
D
Y
D
P
E
A
L
D
G
A
T
R
-
L
A
A
G
H
A
L
----
A
G
Q
--
I
T
L
H
R
Q
D
A
W
K
L
D
--
T
R
-
E
G
--
Y
D
--------
L
L
T
S
N
G
-
L
N
I
Y
E
--
P
D
--
D
A
R
V
T
-
E
L
-
Y
R
R
F
W
Q
A
L
K
P
G
G
A
L
V
T
------------
S
F
L
T
P
P
P
A
L
S
P
D
S
P
W
D
------
M
---
Q
------
A
---
I
D
----
P
-
H
D
L
Q
----
L
Q
Q
----
L
-----
V
-----
F
T
-------
R
L
I
Q
P
R
W
N
A
L
R
T
H
A
Q
T
R
A
Q
L
E
E
A
G
F
T
D
L
R
F
E
D
D
R
A
R
L
F
P
T
V
I
A
R
K
----------------------------------
34
HHSearch
54.18
14%
-102
* C2 *
3PFG
3
TYLM1_STRFR
A:
[10-238]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Q
A
D
Y
S
G
E
I
A
E
L
Y
D
L
V
H
Q
G
---
K
G
K
D
Y
H
R
E
A
A
D
L
A
A
L
V
R
R
H
S
P
K
A
A
S
L
L
D
V
A
C
G
T
G
M
H
L
R
H
L
A
D
S
F
----
G
T
V
-
E
G
L
E
L
S
A
D
M
L
A
I
A
R
R
-
R
N
----------
P
D
--
A
V
L
H
H
G
D
M
R
D
F
S
--
L
G-
R
R
--
F
S
--------
A
V
T
C
M
F
S
S
I
G
H
L
--
A
G
Q
-
A
E
-
L
D
-
A
A
-
L
E
R
F
A
A
H
V
L
P
D
G
V
V
V
V
------------
E
P
W
W
F
P
E
N
F
T
P
G
Y
V
A
A
G
T
V
E
A
G
G
T
T
V
T
------
R
V
S
H
S
S
----
R
E
G
E
A
T
R
I
E
V
H
Y
L
----
V
A
G
PDR
G
-----
I
T
-------
H
H
E
E
S
H
R
I
T
L
F
T
R
E
Q
Y
E
R
A
F
T
A
A
G
L
S
V
E
F
M
P
G
G
P
-
S
G
R
G
L
F
T
G
L
P
----------------------------------
43
Fugue
53.70
13%
-83
- C2 -
4KRI
2
?
C:
[1-433]
ASMP
A
V
E
R
Q
L
I
E
C
L
H
H
V
IKGAEPQ
Q
V
G
I
L
C
PQ
D
D
Q
R
K
A
L
T
E
Q
FGSK
T
A
T
S
F
C
KEVDSLKNLSNLD
A
L
I
V
N
QAL
D
E
E
I
N
D
S
E
K
L
D
K
F
I
T
A
A
L
R
S
LRTD
G
V
L
I
L
R
Q
D
LSKVKEMK
K
M
A
M
L
T
D
Y
F
D
V
F
R
L
E
E
GN
G
N
V
G
F
Q
F
Y
AVNEV
L
D
S
V
Y
VHQNWLD
F
I
W
T
L
M
K
K
P
F
P
V
S
F
R
D
F
L
D
R
T
Q
Y
T
D
T
G
I
F
A
Y
E
W
I
F
G
N
NFI
S
P
G
G
W
N
Q
N
L
A
I
L
K
R
F
G
P
--
M
K
T
G
Q
R
M
L
D
I
G
V
G
I
G
G
G
A
R
Q
A
A
S
E
F
---
G
L
Q
V
-
H
G
V
D
L
S
T
N
M
L
A
V
A
L
E
-
R
V
H
K
E
-----
K
D
A
R
--
V
T
Y
A
V
C
D
A
C
E
Y
E
--
F
--
E
P
--
N
S
--------
F
D
Y
V
F
S
-
R
D
C
I
Q
--
H
I
--
K
D
-
T
D
-
K
L
-
F
S
R
I
Y
R
A
L
K
P
G
G
K
V
L
I
------------
T
M
Y
G
V
G
H
G
T
L
-----
S
------
E
---
S
------
F
K
E
-
Y
V
----
S
Q
R
Q
Y
Y
----
L
K
N
----
L
-----
E
-----
Q
I
-------
E
E
I
A
K
K
T
G
F
I
D
I
E
V
E
N
M
T
P
R
F
K
E
I
L
L
E
E
R
E
R
I
E
Q
-
D
K
E
T
F
L
A
K
F
S
Q
N
A
Y
D
G
L
V
S
G
W
K
S
K
L
Q
Y
I
A
D
DN
H
N
W
N
F
F
A
A
V
K
P
Q
9
PsiBlast_PDB
53.19
27%
-117
- C2 -
3CCF
1
?
A:
[56-151]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
G
E
F
I
L
D
L
G
C
G
T
G
Q
L
T
E
K
I
A
Q
----
S
G
A
E
V
-
L
G
T
D
N
A
A
T
M
I
E
K
A
R
Q
N
Y
P
H
---------
L
H
--
F
D
V
A
D
A
R
N
F
R
V
D
-----
K
P
--
L
D
--------
A
V
F
S
N
A
-
M
L
H
W
V
--
K
E
--
P
E
----
A
A
-
I
A
S
I
H
Q
A
L
K
S
G
G
R
F
V
A
------------
E
F
G
G
K
G
N
I
K
Y
I
L
E
A
L
Y
------
N
---
A
------
L
E
T
-
L
G
----
I
H
N
P
Q
A
----
L
N
P
----
W
-----
Y
-----
F
P
-------
S
I
G
E
Y
V
N
I
L
E
K
Q
G
F
D
V
T
Y
A
A
L
F
N
R
P
T
T
L
A
E
G
E
F
G
-
M
A
N
W
I
Q
M
F
A
S
----------------------------------
39
HHSearch
53.03
19%
-102
- C2 -
1XTP
1
?
A:
[93-237]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
S
R
A
L
D
C
G
A
G
I
G
R
I
T
K
N
L
L
T
K
L
---
Y
A
T
T
-
D
L
L
E
P
V
K
H
M
L
E
E
A
K
R
-
E
L
A
G
-------
M
P
V
--
G
K
F
I
L
A
S
M
E
T
A
T
--
L
P
P
N
T
--
Y
D
--------
L
I
V
I
Q
W
-
T
A
I
Y
L
--
T
D
--
A
D
-
F
V
-
K
F
-
F
K
H
C
Q
Q
A
L
T
P
N
G
Y
I
F
F
------------
K
E
N
C
S
--
D
R
F
----
L
----------------------
V
D
----
K
-----------------------------------------
E
D
S
S
L
T
R
S
D
I
H
Y
K
R
L
F
N
E
S
G
V
R
V
V
K
E
A
F
Q
E
-
E
W
P
T
D
L
F
P
L
K
----------------------------------
30
HHSearch
52.79
18%
-89
- C2 -
3L8D
1
?
A:
[32-200]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
---
M
W
D
--
S
G
S
R
S
T
I
I
P
F
F
E
Q
Y
V
K
K
E
A
E
V
L
D
V
G
C
G
D
G
Y
G
T
Y
K
L
S
R
T
----
G
Y
K
A
-
V
G
V
D
I
S
E
V
M
I
Q
K
G
K
E
-
R
G
E
--------
G
P
D
--
L
S
F
I
K
G
D
L
S
S
L
P
FE
N
--
E
Q
--
F
E
--------
A
I
M
A
I
N
-
S
L
E
W
T
--
E
E
--
P
---
L
-
R
A
-
L
N
E
I
K
R
V
L
K
S
D
G
Y
A
C
I
------------
A
I
L
G
P
T
A
K
P
R
E
N
S
-
Y
P
------
R
--------------
L
-------
Y
-------------------------------------
G
K
D
V
V
C
N
T
M
M
P
W
E
F
E
Q
L
V
K
E
Q
G
F
K
V
V
D
G
I
G
V
Y
-
K
R
G
V
N
E
K
M
L
G
----------------------------------
25
HHSearch
52.05
18%
-89
- C2 -
3OU2
1
?
A:
[11-207]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
S
Y
Y
R
A
R
A
S
E
Y
D
A
T
F
V
P
------
Y
M
D
S
A
A
P
A
A
L
E
R
L
R
A
-
G
N
I
R
G
D
V
L
E
L
A
S
G
T
G
Y
W
T
R
H
L
S
G
L
----
A
D
R
V
-
T
A
L
D
G
S
A
E
M
I
A
E
A
G
R
-
H
G
---------
L
D
N
--
V
E
F
R
Q
Q
D
L
F
D
W
T
P-
D
--
R
Q
--
W
D
--------
A
V
F
F
A
H
-
W
L
A
H
V
--
P
D
--
D
R
-
F
E
-
A
F
-
W
E
S
V
R
S
A
V
A
P
G
G
V
V
E
F
------------
V
D
V
T
D
H
E
---------------------------
V
A
-
V
R
----
R
T
L
--------------------------
Q
D
-------
G
R
S
F
R
I
V
K
V
F
R
S
P
A
E
L
T
E
R
L
T
A
L
G
W
S
C
S
V
D
E
V
H
P
-
G
F
L
Y
A
T
C
R
P
G
----------------------------------
28
HHSearch
51.82
17%
-89
- C2 -
3UJC
1
?
A:
[54-206]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
N
S
K
V
L
D
I
G
S
G
L
G
G
G
C
M
Y
I
N
E
K
Y
---
G
A
H
T
-
H
G
I
D
I
C
S
N
I
V
N
M
A
N
E
-
R
V
S
G
-------
N
N
K
--
I
I
F
E
A
N
D
I
L
T
K
E
--
F
P
E
N
N
--
F
D
--------
L
I
Y
S
R
D
-
A
I
L
A
L
--
S
L
--
E
N
-
K
N
-
K
L
-
F
Q
K
C
Y
K
W
L
K
P
T
G
T
L
L
I
------------
T
D
Y
C
A
T
E
K
E
N
W
D
D
E
F
K
------
E
---
Y
-----------
V
---------------------------------------------
K
Q
R
K
Y
T
L
I
T
V
E
E
Y
A
D
I
L
T
A
C
N
F
K
N
V
V
S
K
D
L
S
-
D
Y
W
N
Q
L
L
E
V
E
----------------------------------