@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0847: (2016-01-22 )
MEPSPRTAAAVKSGACLLTSTLIARLLEGWVAPDDARLPEEYAAQVTQPRRCIEMSNFNSHDRVSLCSQPAARLMLSPITRPHRMPLRTRLLWLFLPLLAASLGGIWLLSESILLSRFDREDQQRLQEGATVLHNRLDFELKRHLDIVRTYAWWDASYDFIQRPNETFEQENLDHEMLDDLGFDFVLFLDDRGHLQLKQWSPPAPDQRVLFGAPSASDQALLEALQQRAIRLGALDFRGRTDHSLSELLLVDNLPTLLVSVPISNNQGSAPAKGAILAGYFLDRERLANLREQMQADLQPMPNIATDSTWKPLRSRSGSTHNQALLSPRRFIGEHVQQVSVQYLSSSGEPQLRFDITKKRLLYIQGEKAINFFLGASLLVALGAFLVGYLALELWVLRRVQRLNREVAEVGRNAHSIRLSDFGNDELGQLAGEMNQMLERLEHSEARDRAILQSMRDGYFEMDVDGVILTVNPALCQLLGQTRETLIGHPYYELLGEDDLARARQPFQRAMQSGAGKTFAIPLQRADGSLGYFEATVSLIHDLQGELRGYRGIVRDVSDQIAYQQQLLEMAYRDPLTGLGNRKAFDEQLGQALLRAGSGGSELALLYLDLDRFKEVNDRFGHDIGDALLRTVAERVRSTLRQPDKAYRLGGDEFAVLLEDSQENNPQRLAERLLAALVQPIALNGERIDFVTPSIGIALYPRHAGDAEGLVRAADSAMYEAKRQRNHYCLYQAPA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......-------570.......580.......590.......600.......610.......620.......630.......640..-......650.......660..-----.-.....670.-......-680--.-.--....---.690.--------.....-.700.....-..710.......720-..-.....730...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEPSPR
T
A
A
A
VKS
G
A
C
L
L
T
S
T
L
I
A
R
L
L
E
G
WVAPDDARL
P
E
E
Y
A
A
Q
VTQP
R
R
C
I
EMSNFNS
H
D
R
V
S
L
C
S
Q
P
A
A
R
L
M
LSPITRPHRM
P
L
R
T
R
L
L
W
L
F
L
P
L
L
A
A
SLG
G
I
W
L
L
S
E
S
I
L
L
S
RFD
R
E
D
Q
Q
R
L
Q
E
G
A
T
V
L
H
N
RL
D
F
E
L
K
R
H
L
D
I
V
R
T
Y
A
W
WDAS
Y
D
F
I
QRPNET
F
E
QENL
D
H
E
M
L
D
DLGF
D
F
V
L
F
LDDRG
H
L
Q
L
KQWSPPAPDQ
R
V
L
F
GAPSA
S
D
Q
A
L
L
E
A
L
Q
Q
R
A
I
RLG
A
L
DFRGRTDH
S
L
S
E
L
L
L
VDNL
P
T
L
L
V
S
V
PISNNQGSAPAK
G
A
I
L
A
G
Y
FL
D
R
E
R
L
A
N
L
R
E
Q
M
Q
A
D
LQPMPNIATDSTW
K
P
L
R
SRSGSTH
N
Q
A
LL
S
P
R
R
F
I
G
E
H
V
Q
Q
V
S
V
Q
Y
L
SSSGE
P
Q
L
R
F
DITK
K
R
L
L
Y
I
QGE
K
A
I
N
F
F
L
G
A
S
L
L
V
A
L
G
A
F
L
V
G
Y
L
A
L
E
L
W
V
L
R
R
V
Q
R
L
N
R
E
V
A
E
VGRNA
H
S
I
R
LSDFGN
D
E
L
G
Q
L
A
G
E
M
N
Q
M
L
E
R
L
E
H
S
E
A
R
D
R
A
I
L
Q
S
M
RDG
Y
F
E
MDVD
G
V
I
L
TV
N
P
A
L
C
Q
L
L
G
Q
T
R
E
T
LIG
H
P
Y
Y
E
L
LG
E
D
D
L
A
R
A
R
Q
P
F
Q
R
A
M
Q
SGAG
K
T
F
A
I
P
L
QRADGSL
G
Y
F
E
A
T
V
S
L
I
H
D
L
Q
G
E
L
R
G
Y
R
G
I
V
R
D
V
S
D
Q
I
A
Y
Q
Q
Q
L
L
E
-------
M
A
Y
RDPLTGLGN
R
K
A
F
D
E
Q
L
G
Q
A
L
L
RAGSGG
S
E
L
A
L
L
Y
L
D
L
D
R
F
K
E
V
N
D
RFG
H
D
I
G
D
A
L
L
R
T
V
A
E
R
V
R
S
T
L-RQ
P
-
D
K
A
Y
RLGG
D
E
F
A
V
L
LED-SQE-----N-
N
P
Q
R
L
A
E
R
L
-
L
A
A
L
V
Q
-
P
IA--L-N--G
E
R
I
---
D
F
VTP--------SI
G
I
A
-
L
YPRHAG
D
A
-
E
G
L
V
R
A
A
D
S
A
M
Y
E
A
K
-RQ-RN
H
Y
C
L
Y
QAPA
21
PsiBlast_CBE
82.44
38%
-79
- C1 -
4URS
7
?
B:
[27-184]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
H
D
P
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
D
R
V
-
R
R
S
-
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
-
M
K
E
-----
E
-
Y
L
K
S
L
L
E
R
I
-
L
S
T
F
R
E
-
P
V
R
--
V
-
E
--
N
K
H
L
---
S
-
V
T
P
--------
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
-
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
-
E
M
-
K
V
P
Y
F
S
L
S
---
1
PsiBlast_PDB
82.34
38%
-78
- C1 -
4URS
6
?
A:
[27-184]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
H
D
P
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
D
R
V
-
R
R
S
-
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
-
M
K
E
-----
E
-
Y
L
K
S
L
L
E
R
I
-
L
S
T
F
R
E
-
P
V
R
--
V
-
E
--
N
K
H
L
---
S
-
V
T
P
--------
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
-
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
-
E
M
-
K
V
P
Y
F
S
L
S
---
2
PsiBlast_PDB
81.56
41%
-93
- C1 -
4RNH
-
?
A:
[21-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
Y
D
A
L
T
H
L
P
N
R
T
L
F
Q
D
R
L
H
T
A
L
Q
Q
A
E
R
N
G
Q
W
V
V
L
M
F
L
D
L
D
R
F
------
L
G
H
A
A
G
D
R
M
L
Q
E
V
A
T
R
L
S
A
C
V
-
S
Q
D
-
D
T
V
A
R
M
G
G
D
E
F
T
L
L
L
P
S
-
Q
G
D
R
E
I
A
L
K
-
R
A
I
Q
V
A
E
L
I
-
L
G
R
L
A
R
-
P
F
T
--
L
-
E
--
G
R
E
F
----
F
V
T
A
--------
S
I
G
V
A
-
L
S
P
Q
D
G
A
E
L
-
S
L
L
M
K
N
A
D
T
A
M
Y
H
A
K
-
E
M
G
K
N
N
F
Q
F
Y
Q
A
E
M
36
HHSearch
81.21
41%
-87
- C1 -
3ICL
3
?
A:
[1-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
T
V
T
G
L
P
N
R
Q
L
F
C
D
R
L
L
Q
A
L
A
A
H
E
R
D
G
N
P
V
V
L
L
F
L
D
V
D
N
F
K
S
I
N
D
S
L
G
H
L
V
G
D
R
L
L
R
A
T
A
E
R
I
R
T
A
V
-
R
D
G
-
D
T
V
A
R
I
G
G
D
K
F
T
I
L
L
N
G
-
A
K
D
T----
L
-
N
G
A
L
V
A
Q
K
I
-
L
D
G
L
A
Q
-
P
F
V
--
F
-
G
--
A
Q
Q
I
----
V
I
S
V
--------
S
I
G
I
A
-
V
S
P
A
D
G
E
T
M
-
E
Q
L
L
R
N
A
D
T
A
M
Y
H
A
K
-
S
R
G
K
N
N
Y
Q
F
F
S
P
--
4
PsiBlast_PDB
80.84
41%
-85
- C1 -
3ICL
3
?
A:
[2-160]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
V
T
G
L
P
N
R
Q
L
F
C
D
R
L
L
Q
A
L
A
A
H
E
R
D
G
N
P
V
V
L
L
F
L
D
V
D
N
F
K
S
I
N
D
S
L
G
H
L
V
G
D
R
L
L
R
A
T
A
E
R
I
R
T
A
V
-
R
D
G
-
D
T
V
A
R
I
G
G
D
K
F
T
I
L
L
N
G
-
A
K
D
-----
T
L
N
G
A
L
V
A
Q
K
I
-
L
D
G
L
A
Q
-
P
F
V
--
F
-
G
--
A
Q
Q
I
----
V
I
S
V
--------
S
I
G
I
A
-
V
S
P
A
D
G
E
T
M
-
E
Q
L
L
R
N
A
D
T
A
M
Y
H
A
K
S
R
G
-
K
N
N
Y
Q
F
F
S
P
--
7
PsiBlast_PDB
80.77
38%
-78
- C1 -
4URQ
-
?
U:
[4-155]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
D
R
V
-
A
R
S
-
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
-
M
K
E
-----
E
-
Y
L
K
S
L
L
E
R
I
-
L
S
T
F
R
E
-
P
V
R
--
V
-
E
--
N
K
H
L
---
S
-
V
T
P
--------
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
-
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
-
E
M
-
K
V
P
Y
F
S
-----
6
PsiBlast_PDB
80.18
39%
-78
- C1 -
4URG
2
?
A:
[2-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
D
R
V
-
R
R
S
-
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
-
M
K
E
-----
E
-
Y
L
K
S
L
L
E
R
I
-
L
S
T
F
R
E
-
P
V
R
--
V
-
E
--
N
K
H
L
---
S
-
V
T
P
--------
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
-
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
-
E
-------------
5
PsiBlast_PDB
80.10
46%
-72
- C1 -
4IOB
2
?
A:
[1-150]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
S
L
P
N
R
A
F
F
E
G
R
L
S
R
A
L
R
D
A
N
E
H
R
E
Q
L
A
V
L
F
I
D
S
D
R
F
K
E
I
N
D
R
L
G
H
A
A
G
D
T
V
L
V
N
I
A
M
R
I
R
G
Q
L
-
R
E
S
-
D
L
V
A
R
L
G
G
D
E
F
A
V
L
L
A
P
L
A
S
G
-----
A
-
D
A
L
R
I
A
D
N
I
-
I
A
S
M
Q
A
-
P
I
R
--
L
-
S
--
D
G
S
T
---
V
S
T
S
L
--------
T
I
G
I
A
-
L
Y
P
E
H
A
D
T
P
-
A
A
L
L
H
D
A
D
M
A
M
Y
I
A
K
-
R
Q
-
A
R
G
S
R
R
L
A
E
L
N
28
PsiBlast_CBE
79.65
33%
-68
- C1 -
4H54
4
YDEH_ECOLI
B:
[132-286]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
L
T
G
L
P
G
R
R
V
L
D
E
S
F
D
H
Q
L
R
N
A
E
P
--
L
N
L
Y
L
M
L
L
D
I
D
R
F
K
L
V
N
D
T
Y
G
H
L
I
G
D
V
V
L
R
T
L
A
T
Y
L
A
S
W
T
-
R
D
Y
-
E
T
V
Y
R
Y
G
G
E
E
F
I
I
I
V
K
A
-
A
N
D
-----
E
-
E
A
C
R
A
G
V
R
I
-
C
Q
L
V
D
N
-
H
A
I
--
T
-
H
--
S
E
G
H
---
I
N
I
T
V
--------
T
A
G
V
S
R
A
F
P
E
E
P
L
D
V
---
V
I
G
R
A
D
R
A
M
Y
E
G
K
-
Q
T
-
G
R
N
R
C
M
F
I
D
E
Q
3
PsiBlast_PDB
79.23
41%
-86
- C1 -
4RNF
-
?
A:
[21-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
Y
D
A
L
T
H
L
P
N
R
T
L
F
Q
D
R
L
H
T
A
L
Q
Q
A
E
R
N
G
Q
W
V
V
L
M
F
L
D
L
D
-----
N
D
S
L
G
H
A
A
G
D
R
M
L
Q
E
V
A
T
R
L
S
A
C
V
-
S
Q
D
-
D
T
V
A
R
M
G
G
D
E
F
T
L
L
L
P
S
-
Q
G
D
R
E
I
A
L
K
-
R
A
I
Q
V
A
E
L
I
-
L
G
R
L
A
R
-
P
F
T
--
L
-
E
--
G
R
E
F
----
F
V
T
A
--------
S
I
G
V
A
-
L
S
P
Q
D
G
A
E
L
-
S
L
L
M
K
N
A
D
T
A
M
Y
H
A
K
-
E
M
G
K
N
N
F
Q
F
Y
Q
A
E
M
35
HHSearch
78.46
38%
-81
- C1 -
1W25
3
PLED_CAUCN
A:
[281-454]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
H
S
L
E
-------
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
-
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
-
T
A
L
-----
A
-
D
A
L
R
I
A
E
R
I
-
R
M
H
V
S
G
S
P
F
T
--
V
-
A
HG
R
E
M
L
----
N
V
T
I
--------
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
-
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
-
A
S
G
R
N
A
V
V
G
K
A
A
H
-
16
PsiBlast_PDB
77.93
33%
-69
- C1 -
4H54
5
YDEH_ECOLI
A:
[132-286]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
L
T
G
L
P
G
R
R
V
L
D
E
S
F
D
H
Q
L
R
N
A
E
P
--
L
N
L
Y
L
M
L
L
D
I
D
R
F
K
L
V
N
D
T
Y
G
H
L
I
G
D
V
V
L
R
T
L
A
T
Y
L
A
S
W
T
-
R
D
Y
-
E
T
V
Y
R
Y
G
G
E
E
F
I
I
I
V
K
A
-
A
N
D
-----
E
-
E
A
C
R
A
G
V
R
I
-
C
Q
L
V
D
N
-
H
A
I
--
T
-
H
--
S
E
G
H
---
I
N
I
T
V
--------
T
A
G
V
S
R
A
F
P
E
E
P
L
D
V
---
V
I
G
R
A
D
R
A
M
Y
E
G
K
-
Q
T
-
G
R
N
R
C
M
F
I
D
E
Q
9
PsiBlast_PDB
77.37
37%
-74
- C1 -
1W25
3
PLED_CAUCN
A:
[285-452]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
-------
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
-
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
-
T
A
L
-----
A
-
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
-
P
F
T
--
V
A
H
--
G
R
E
M
---
L
N
V
T
I
--------
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
-
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
-
A
S
-
G
R
N
A
V
V
G
K
A
A
H
14
PsiBlast_PDB
77.29
37%
-67
- C1 -
3BRE
2
?
A:
[157-338]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
Q
L
L
E
T
N
L
V
L
Q
R
L
M
N
S
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
M
E
W
R
R
S
L
R
E
Q
S
Q
L
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
-
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
-
T
S
P
-----
G
-
G
A
R
L
L
A
E
K
V
-
R
R
T
-
V
E
-
S
L
Q
--
I
-
S
--
H
D
Q
P
RP
G
S
H
L
T
V
--------
S
I
G
V
S
T
L
V
P
G
G
G
G
Q
T
F
R
V
L
I
E
M
A
D
Q
A
L
Y
Q
A
K
-
N
N
G
R
N
Q
V
G
L
M
E
Q
--
24
PsiBlast_CBE
76.71
37%
-70
- C1 -
1W25
2
PLED_CAUCN
B:
[285-452]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
-------
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
-
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
-
T
A
L
-----
A
-
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
-
P
F
T
--
V
A
H
--
G
R
E
M
---
L
N
V
T
I
--------
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
-
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
-
A
S
-
G
R
N
A
V
V
G
K
A
A
H
23
PsiBlast_CBE
76.64
37%
-71
- C1 -
2V0N
6
PLED_CAUCN
B:
[285-452]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
-------
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
-
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
-
T
A
L
-----
A
-
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
-
P
F
T
--
V
A
H
--
G
R
E
M
---
L
N
V
T
I
--------
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
-
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
-
A
S
-
G
R
N
A
V
V
G
K
A
A
H
12
PsiBlast_PDB
76.45
36%
-71
- C1 -
3I5A
2
?
A:
[155-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
Q
L
L
D
T
N
L
V
L
Q
R
L
M
N
S
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
L
E
W
R
R
A
T
R
D
Q
A
Q
L
S
L
L
M
I
D
V
D
Y
F
K
A
Y
N
D
N
F
G
H
L
E
G
D
E
A
L
R
Q
V
A
K
A
I
R
N
S
C
-
S
R
P
S
D
L
P
A
R
Y
G
G
E
E
F
A
M
V
L
P
N
-
T
S
P
-----
G
-
G
A
R
L
L
A
E
K
L
-
R
Q
S
V
A
------------
G
M
N
I
---
P
H
I
A
P
VPGS
S
L
T
V
S
I
G
V
A
T
V
T
P
Q
V
G
Q
H
S
-
R
Q
L
I
L
D
A
D
K
G
L
Y
L
A
K
-
N
N
-
G
R
N
Q
V
A
A
G
---
58
Fugue
76.41
19%
-37
- C1 -
1W25
4
PLED_CAUCN
A:
[1-454]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
D
P
T
T
R
H
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
G
L
E
S
--
G
A
S
D
F
L
T
-
K
P
I
D
D
V
M
L
F
A
R
V
R
S
L
T
R
F
K
L
V
I
D
E
L
R
Q
R
E
A
S
G
R
R
M
G
V
I
A
G
A
A
A
R
L
D
G
L
G
G
R
V
L
I
V
D
D
N
E
R
Q
A
Q
R
V
A
A
E
L
G
V
E
H
R
P
V
I
E
S
D
P
E
K
A
K
I
S
A
G
G
P
V
D
L
V
I
V
N
A
A
A
K
N
F
D
G
L
R
F
T
A
A
L
R
S
E
---
E
R
T
R
Q
L
P
V
L
A
M
V
D
P
D
D
R
G
R
M
V
K
A
L
E
I
G
V
N
D
I
L
S
R
P
I
D
-
P
Q
E
L
S
A
R
V
K
T
Q
I
Q
R
K
R
Y
T
D
Y
L
R
N
N
L
D
H
S
L
E
-------
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
-
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
-
T
A
L
-----
A
-
D
A
L
R
I
A
E
R
I
-
R
M
H
V
S
G
-
S
P
F
T
V
A
-
H
--
G
R
E
M
---
L
N
V
T
I
--------
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
-
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
-
A
S
G
R
N
A
V
V
G
K
A
A
H
-
15
PsiBlast_PDB
76.34
38%
-61
- C1 -
3I5B
2
?
A:
[6-170]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
M
E
W
R
R
S
L
R
E
Q
S
Q
L
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
-
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
-
T
S
P
-----
G
-
G
A
R
L
L
A
E
K
V
-
R
R
T
-
V
E
-
S
L
Q
--
I
-
S
--
H
D
Q
P
RPG
S
H
L
T
V
--------
S
I
G
V
S
T
L
V
P
G
G
G
G
Q
T
F
R
V
L
I
E
M
A
D
Q
A
L
Y
Q
A
K
-
N
N
G
R
N
Q
V
G
L
M
E
---
25
PsiBlast_CBE
76.29
36%
-64
- C1 -
3I5C
4
GCN4_YEAST
B:
[25-198]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
K
K
-------
L
V
N
S
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
M
E
W
R
R
S
L
R
E
Q
S
Q
L
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
-
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
-
T
S
P
-----
G
-
G
A
R
L
L
A
E
K
V
-
R
R
T
-
V
E
-
S
L
Q
--
I
-
S
--
H
D
Q
P
RPG
S
H
L
T
V
--------
S
I
G
V
S
T
L
V
P
G
G
G
G
Q
T
F
R
V
L
I
E
M
A
D
Q
A
L
Y
Q
A
K
-
N
N
G
R
N
Q
V
G
L
M
E
Q
--