@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA1120: (2016-01-26 )
MNRRRRYTGSNPSLRRVLYRAHLGVALVAVFTAGLAVTLVGLLTLRAYADPNQQLIARSISYTVEAAVVFGDAQAAEESLALIASSEEVSSAIVYDRQGQTLASWHRESTGPLHLLEQQLAHWLLSAPTEQPILHDGQKIGSVEVKGSGGSLLRFLLTGFAGMVLCLLLTALGAFYLSRRLVRGIVGPLDQLAKVAHTVRRERDFEKRVPEAGIAELSQLGEDFNALLDELESWQARLQDENASLAHQAHHDSLTSLPNRAFFEGRLSRALRDANEHREQLAVLFIDSDRFKEINDRLGHAAGDTVLVNIAMRIRGQLRESDLVARLGGDEFAVLLAPLASGADALRIADNIIASMQAPIRLSDGSTVSTSLTIGIALYPEHADTPAALLHDADMAMYIAKRQARGSRRLAELNDPRILQEEKEIDSATPEAPPK
Atome Classification :
(20 SA)
-----------------------.........10........20........30....-....40......--------..50........60........70........80........90........100.......110.......120...---....130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240..------.-....250.......260.......270.......280.......290.......300.......310...-...-.320.......330.......340....------.-..350---....-.-.-.-360.-..-....370.....-..380.......390.......400.......410.......420.......430...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------MNRRRRYTGS
N
P
S
L
R
R
V
L
Y
R
A
H
L
G
V
A
L
V
A
V
F
TA
G
L
-
A
V
T
L
V
G
L
L
T
L
R
A--------YADP
N
Q
Q
L
I
A
R
S
I
S
Y
T
V
E
A
A
V
V
FGD
A
Q
A
A
E
E
S
L
A
L
I
AS
S
E
EV
S
S
A
I
V
YDRQG
Q
T
L
A
S
W
HRESTG
P
L
H
L
L
E
Q
Q
L
A
H
W
L
L---SAPTEQPILHDGQKI
G
S
V
E
V
KGS
G
G
S
L
L
R
F
L
L
T
G
F
A
G
M
V
L
C
L
L
L
T
A
L
G
A
F
Y
L
S
R
R
L
V
R
G
I
V
G
P
L
D
Q
L
A
K
V
A
H
T
V
R
R
E
R
D
F
E
K
RVPE
A
G
I
A
E
L
S
Q
L
G
E
D
F
N
A
L
L
D
E
L
E
S
W
Q
A
R
LQDENA
S
------
L
-
A
H
Q
AHH
D
S
L
T
SLP
N
R
A
F
F
E
G
R
L
S
R
A
L
R
D
A
N
E
H
R
E
Q
L
A
V
L
F
ID
S
D
R
F
K
E
I
N
D
R
LGHAAG
D
T
V
L
V
N
I
A
M
R
I
R
-GQL-R
E
S
D
L
V
A
R
LGGD
E
F
A
V
L
L
A
P
L
ASGA
D
A
L
------
R
-
I
A
D
N
I
---
I
A
S
M-Q-A-
P
-
I
R
LS-DG-
S
T
V
S
T
S
L
T
I
G
I
A
-
L
YPEHAD
T
P
A
A
L
L
HD
A
D
M
A
M
Y
I
A
K
R
QARGSRRLAELNDP
R
I
L
Q
E
E
K
EIDSATPEAPPK
1
PsiBlast_PDB
87.39
100%
-119
- C6 -
4IOB
2
?
A:
[1-161]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
S
L
P
N
R
A
F
F
E
G
R
L
S
R
A
L
R
D
A
N
E
H
R
E
Q
L
A
V
L
F
I
D
S
D
R
F
K
E
I
N
D
R
L
G
H
A
A
G
D
T
V
L
V
N
I
A
M
R
I
R
-
G
Q
L
-
R
E
S
D
L
V
A
R
L
G
G
D
E
F
A
V
L
L
A
P
L
A
S
G
A
D
A
L
------
R
-
I
A
D
N
I
---
I
A
S
M
-
Q
-
A
-
P
-
I
R
L
S
-
D
G
-
S
T
V
S
T
S
L
T
I
G
I
A
-
L
Y
P
E
H
A
D
T
P
A
A
L
L
H
D
A
D
M
A
M
Y
I
A
K
R
Q
A
R
G
S
R
R
L
A
E
L
N
---------------------
59
Fugue
79.66
21%
-77
* C8 *
1W25
4
PLED_CAUCN
A:
[1-454]
S
A
R
I
L
V
V
D
DI
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
D
P
TTRH
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
L
T
R
F
K
L
V
I
D
E
L
R
Q
R
E
A
S
G
R
R
M
G
V
I
A
G
A
A
A
R
L
D
G
L
G
G
R
V
L
I
V
D
D
N
E
R
Q
A
Q
R
V
A
A
E
L
G
V
E
H
R
P
V
I
E
S
D
P
E
K
A
K
I
S
A
G
G
P
V
D
L
V
I
V
N
A
A
A
K
N
F
D
G
L
R
F
T
A
A
L
R
S
E
--
E
R
T
R
Q
L
P
V
L
A
M
V
D
P
D
D
R
G
R
M
V
K
A
L
E
I
G
V
N
D
I
L
S
R
P
I
D
P
Q
E
L
S
A
R
V
K
T
Q
I
Q
R
K
R
Y
T
D
Y
L
R
N
NLDH
S
-
L
E
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
-
P
D
T
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
-
G
S
P
-
F
T
V
A
-
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
---------------------
5
PsiBlast_PDB
72.53
40%
-130
- C6 -
4URG
2
?
A:
[1-149]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
D
P
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
-
D
R
V
-
R
R
S
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
M
K
E
--
E
Y
L
------
K
S
L
L
E
R
I
---
L
S
T
F
-
R
-
E
-
P
-
V
R
V
--
E
N
-
K
H
L
S
V
T
P
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
E
---------------------------------
4
PsiBlast_PDB
72.19
39%
-133
- C6 -
4URS
6
?
A:
[27-178]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
H
D
P
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
-
D
R
V
-
R
R
S
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
M
K
E
--
E
Y
L
------
K
S
L
L
E
R
I
---
L
S
T
F
-
R
-
E
-
P
-
V
R
V
E
-
N
--
K
H
L
S
V
T
P
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
E
M
K
V
P
Y
F
S
L
S
------------------------
18
PsiBlast_PDB
71.80
30%
-103
- C6 -
4H54
5
YDEH_ECOLI
A:
[103-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
A
F
Q
E
G
L
L
S
F
T
A
A
L
T
D
Y
K
I
Y
------
L
L
T
I
R
S
N
M
D
V
L
T
G
L
P
G
R
R
V
L
D
E
S
F
D
H
Q
L
R
N
A
E
P
--
L
N
L
Y
L
M
L
L
D
I
D
R
F
K
L
V
N
D
T
Y
G
H
L
I
G
D
V
V
L
R
T
L
A
T
Y
L
A
-
S
W
T
-
R
D
Y
E
T
V
Y
R
Y
G
G
E
E
F
-
I
I
I
V
K
A
A
N
D
E
E
A
C
------
R
-
A
G
V
R
I
---
C
Q
L
V
D
N
-
H
-
A
-
I
T
H
S
-
E
G
-
H
-
I
N
I
T
V
T
A
G
V
S
R
A
F
P
E
--
E
P
L
D
V
V
I
G
R
A
D
R
A
M
Y
E
G
K
Q
T
G
R
N
R
C
M
F
I
D
E
Q
N
V
I
N
R
V
---------------
36
HHSearch
71.52
36%
-108
- C6 -
3ICL
3
?
A:
[1-162]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
T
V
T
G
L
P
N
R
Q
L
F
C
D
R
L
L
Q
A
L
A
A
H
E
R
D
G
N
P
V
V
L
L
F
L
D
V
D
N
F
K
S
I
N
D
S
L
G
H
L
V
G
D
R
L
L
R
A
T
A
E
R
I
R
-
T
A
V
-
R
D
G
D
T
V
A
R
I
G
G
D
K
F
T
I
L
L
N
G
A
K
D
T
L
N
G
A
------
L
-
V
A
Q
K
I
---
L
D
G
L
-
A
-
Q
-
P
-
F
V
F
--
G
A
-
Q
Q
I
V
I
S
V
S
I
G
I
A
-
V
S
P
A
D
G
E
T
M
E
Q
L
L
R
N
A
D
T
A
M
Y
H
A
K
S
R
G
K
N
N
Y
Q
F
F
S
P
----------------------
6
PsiBlast_PDB
70.82
37%
-110
- C6 -
3ICL
3
?
A:
[2-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
V
T
G
L
P
N
R
Q
L
F
C
D
R
L
L
Q
A
L
A
A
H
E
R
D
G
N
P
V
V
L
L
F
L
D
V
D
N
F
K
S
I
N
D
S
L
G
H
L
V
G
D
R
L
L
R
A
T
A
E
R
I
R
-
T
A
V
-
R
D
G
D
T
V
A
R
I
G
G
D
K
F
T
I
L
L
N
G
A
K
D
T
L
N
G
A
------
L
-
V
A
Q
K
I
---
L
D
G
L
-
A
-
Q
-
P
-
F
V
F
G
--
A
-
Q
Q
I
V
I
S
V
S
I
G
I
A
-
V
S
P
A
D
G
E
T
M
E
Q
L
L
R
N
A
D
T
A
M
Y
H
A
K
S
R
G
K
N
N
Y
Q
F
F
S
P
----------------------
21
PsiBlast_CBE
70.71
39%
-132
- C6 -
4URS
7
?
B:
[27-178]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
H
D
P
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
-
D
R
V
-
R
R
S
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
M
K
E
--
E
Y
L
------
K
S
L
L
E
R
I
---
L
S
T
F
-
R
-
E
-
P
-
V
R
V
E
-
N
--
K
H
L
S
V
T
P
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
E
M
K
V
P
Y
F
S
L
S
------------------------
7
PsiBlast_PDB
69.81
39%
-134
- C6 -
4URQ
-
?
U:
[4-149]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
G
L
P
N
R
R
Y
F
F
E
L
G
N
R
Y
L
D
L
A
K
R
E
G
K
K
V
F
V
L
F
V
D
L
A
G
F
K
A
I
N
D
T
Y
G
H
L
S
G
D
E
V
L
K
T
V
S
K
R
I
L
-
D
R
V
-
A
R
S
D
V
V
A
R
Y
G
G
D
E
F
T
I
L
L
Y
D
M
K
E
--
E
Y
L
------
K
S
L
L
E
R
I
---
L
S
T
F
-
R
-
E
-
P
-
V
R
V
--
E
N
-
K
H
L
S
V
T
P
N
I
G
V
A
-
R
F
P
E
D
G
E
N
L
E
E
L
L
K
V
A
D
M
R
M
Y
K
A
K
E
M
K
V
P
Y
F
S
--------------------------
37
HHSearch
69.29
34%
-105
- C6 -
1W25
3
PLED_CAUCN
A:
[280-454]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
D
H
------
S
-
L
E
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
-
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
-
G
S
P
-
F
T
V
A
H
G
R
-
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
---------------------
10
PsiBlast_PDB
69.25
37%
-103
- C6 -
2V0N
8
PLED_CAUCN
A:
[291-447]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
-
P
D
T
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
G
S
-
P
-
F
T
V
A
-
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
H
H
H
H
H
----------------
8
PsiBlast_PDB
68.96
37%
-104
- C6 -
2WB4
5
PLED_CAUCN
A:
[292-448]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
-
P
D
T
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
G
S
-
P
-
F
T
V
A
-
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
H
H
H
H
-----------------
9
PsiBlast_PDB
68.87
37%
-110
- C6 -
1W25
3
PLED_CAUCN
A:
[291-447]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
-
P
D
T
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
G
S
-
P
-
F
T
V
A
-
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
---------------------
26
PsiBlast_CBE
68.84
33%
-69
- C6 -
3BRE
2
?
B:
[143-338]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
Q
R
D
E
A
Y
R
A
L
R
E
S
----
Q
Q
Q
L
L
E
T
N
L
V
------
L
-
Q
R
L
M
N
S
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
M
E
W
R
R
S
L
R
E
Q
S
Q
L
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
-
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
-
T
V
E
S
L
---
Q
I
S
H
-
D
-
Q
-
P
----
R
-
P
G
-
S
H
L
T
V
S
I
G
V
S
T
L
-
V
P
G
G
G
G
Q
T
F
R
V
L
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
Q
P
---------------------
13
PsiBlast_PDB
68.20
38%
-95
- C6 -
3I5A
2
?
A:
[155-329]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
Q
L
L
D
T
N
L
V
------
L
-
Q
R
L
M
N
S
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
L
E
W
R
R
A
T
R
D
Q
A
Q
L
S
L
L
M
I
D
V
D
Y
F
K
A
Y
N
D
N
F
G
H
L
E
G
D
E
A
L
R
Q
V
A
K
A
I
R
-
N
S
C
S
R
P
S
D
L
P
A
R
Y
G
G
E
E
F
A
M
V
L
-
P
N
T
S
P
G
G
A
R
------
L
-
L
A
E
K
L
R
Q
S
V
A
G
M
-
N
-
I
-
P
H
I
A
P
V
-
P
G
-
S
S
L
T
V
S
--
I
G
V
A
T
V
T
P
Q
V
G
Q
H
S
R
Q
L
I
L
D
A
D
K
G
L
Y
L
A
K
N
N
G
R
N
Q
V
A
A
G
------------------------
22
PsiBlast_CBE
67.98
37%
-107
- C6 -
2WB4
7
PLED_CAUCN
B:
[292-448]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
-
P
D
T
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
G
S
-
P
-
F
T
V
A
-
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
----------------------
16
PsiBlast_PDB
67.90
29%
-87
- C6 -
3IGN
2
?
A:
[5-163]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
L
S
M
T
D
R
L
T
G
L
L
N
R
G
T
W
E
N
L
V
D
A
E
Y
E
R
F
R
R
Y
G
Q
A
T
S
L
V
M
F
D
I
D
H
F
K
P
V
N
D
T
Y
G
H
L
A
G
D
E
V
I
R
H
T
A
D
V
T
R
-
N
N
I
-
R
Q
S
D
S
A
G
R
Y
G
G
E
E
F
G
I
I
L
-
P
E
T
D
A
E
S
A
R
------
V
-
I
C
E
R
I
---
R
E
A
I
-
E
-
K
-
S
-
T
V
S
T
-
S
A
-
G
D
I
Q
Y
T
V
S
M
G
I
A
-
Q
L
T
E
T
P
E
N
Y
M
Q
W
M
Q
K
A
D
E
A
L
Y
K
A
K
E
S
G
R
N
K
V
V
V
S
L
-----------------------
24
PsiBlast_CBE
67.85
37%
-110
- C6 -
1W25
2
PLED_CAUCN
B:
[291-447]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
-
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
-
P
D
T
A
L
A
D
A
L
------
R
-
I
A
E
R
I
---
R
M
H
V
-
S
G
S
-
P
-
F
T
V
A
-
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
-
A
T
A
G
E
G
D
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
---------------------
35
HHSearch
67.74
27%
-87
- C6 -
3IGN
2
?
A:
[5-170]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
L
S
M
T
D
R
L
T
G
L
L
N
R
G
T
W
E
N
L
V
D
A
E
Y
E
R
F
R
R
Y
G
Q
A
T
S
L
V
M
F
D
I
D
H
F
K
P
V
N
D
T
Y
G
H
L
A
G
D
E
V
I
R
H
T
A
D
V
T
R
-
N
N
I
-
R
Q
S
D
S
A
G
R
Y
G
G
E
E
F
G
I
I
L
P
E
T
D
-
A
E
S
A
R
------
V
-
I
C
E
R
I
---
R
E
A
I
-
E
-
K
-
S
-
T
V
S
T
-
S
A
-
G
D
I
Q
Y
T
V
S
M
G
I
A
-
Q
L
T
E
T
P
E
N
Y
M
Q
W
M
Q
K
A
D
E
A
L
Y
K
A
K
E
S
G
R
N
K
V
V
V
S
L
-----------------------
14
PsiBlast_PDB
67.37
33%
-69
- C6 -
3BRE
2
?
A:
[143-338]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
Q
R
D
E
A
Y
R
A
L
R
E
S
----
Q
Q
Q
L
L
E
T
N
L
V
------
L
-
Q
R
L
M
N
S
D
G
L
T
G
L
S
N
R
R
H
F
D
E
Y
L
E
M
E
W
R
R
S
L
R
E
Q
S
Q
L
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
-
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
-
T
V
E
S
L
---
Q
I
S
H
-
D
-
Q
-
P
----
R
-
P
G
-
S
H
L
T
V
S
I
G
V
S
T
L
-
V
P
G
G
G
G
Q
T
F
R
V
L
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
Q
----------------------