@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA1796: (2016-02-01 )
MTAQLIDGKAIAANLRQQIAQRVTERRQQGLRVPGLAVILVGTDPASQVYVAHKRKDCEEVGFLSQAYDLPAETSQDDLLALIDRLNDDPAIDGILVQLPLPAHLDASLLLERIHPDKDVDGFHPYNIGRLAQRMPLLRPCTPKGIMTLLASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSRADLVVVAAGKPGLVKGEWIKEGAIVIDVGINRQADGRLVGDVEYEVAAQRASWITPVPGGVGPMTRACLLENTLHAAEHLHD
Atome Classification :
(30 SA)
.........10........20...--..-----..-.-30....----....40........50........60....--....70........80........90........100.--.--.....110.......120.......130-.--.--.-.--..-..140.......150.......160-.........170.......180.......190-...--.....200.......210.......220.......230------.-----.....------.-240.......250.......260.......270.......280..----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTAQLID
G
K
A
I
A
A
N
L
R
Q
Q
I
A
Q
R
V
T
--
E
R
-----
R
Q-Q-GLRVP
G
----
L
A
V
I
L
V
GTDPA
S
Q
V
Y
V
A
HKRK
D
C
E
E
VG
F
L
S
--
Q
AYDLPAETS
Q
D
D
L
L
A
L
I
D
RLNDDPAI
D
G
I
L
V
QLPLPA--H--L
D
A
S
L
L
L
E
RIHPDKDVDGFHPY
N
I
G
R
L
--
A
--
Q
--R-M--PL-LRPCT
P
K
G
I
M
T
L
L
A
STGADLYG
M
---
D
A
V
V
VGASNIVGR
P
M
A
L
E
L
L
LGG
C
T
V
T
V
T
H
R
--
F
T
R
--
D
L
A
D
HVSRA
D
L
V
V
V
AAGKPGLVK
G
E
W
IKE
G
A
I
V
I
DVGI------N-----RQADG------
R
-
L
V
G
D
V
E
Y
E
V
A
A
QRA
S
W
ITPVPGGV
G
P
M
T
R
A
C
L
L
E
N
T
L
H
A
A
E
HLHD----
1
PsiBlast_PDB
93.45
100%
-114
- C7 -
4A5O
2
FOLD_PSEAE
A:
[4-286]
-
T
A
Q
L
I
D
G
K
A
I
A
A
N
L
R
Q
Q
I
A
Q
R
V
T
--
E
R
-----
R
Q
-
Q
-
G
L
R
V
P
G
----
L
A
V
I
L
V
G
T
D
P
A
S
Q
V
Y
V
A
H
K
R
K
D
C
E
E
V
G
F
L
S
--
Q
A
Y
D
L
P
A
E
T
S
Q
D
D
L
L
A
L
I
D
R
L
N
D
D
P
A
I
D
G
I
L
V
Q
L
P
L
P
A
--
H
--
L
D
A
S
L
L
L
E
R
I
H
P
D
K
D
V
D
G
F
H
P
Y
N
I
G
R
L
--
A
--
Q
--
R
-
M
--
P
L
-
L
R
P
C
T
P
K
G
I
M
T
L
L
A
S
T
G
A
D
L
Y
G
M
---
D
A
V
V
V
G
A
S
N
I
V
G
R
P
M
A
L
E
L
L
L
G
G
C
T
V
T
V
T
H
R
--
F
T
R
--
D
L
A
D
H
V
S
R
A
D
L
V
V
V
A
A
G
K
P
G
L
V
K
G
E
W
I
K
E
G
A
I
V
I
D
V
G
I
------
N
-----
R
Q
A
D
G
------
R
-
L
V
G
D
V
E
Y
E
V
A
A
Q
R
A
S
W
I
T
P
V
P
G
G
V
G
P
M
T
R
A
C
L
L
E
N
T
L
H
A
A
E
H
L
H
D
----
67
HHSearch
87.38
67%
-118
- C7 -
1B0A
-
FOLD_ECOLI
A:
[2-283]
-
A
A
K
I
I
D
G
K
T
I
A
Q
Q
V
R
S
E
V
A
Q
K
V
Q
--
A
R
-----
I
A
-
A
-
G
L
R
A
P
G
----
L
A
V
V
L
V
G
S
N
P
A
S
Q
I
Y
V
A
S
K
R
K
A
C
E
E
V
G
F
V
S
--
R
S
Y
D
L
P
E
T
T
S
E
A
E
L
L
E
L
I
D
T
L
N
A
D
N
T
I
D
G
I
L
V
Q
L
P
L
P
A
--
G
--
I
D
N
V
K
V
L
E
R
I
H
P
D
K
D
V
D
G
F
H
P
Y
N
V
G
R
L
--
C
--
Q
--
R
-
A
--
P
R
-
L
R
P
C
T
P
R
G
I
V
T
L
L
E
R
Y
N
I
D
T
F
G
L
---
N
A
V
V
I
G
A
S
N
I
V
G
R
P
M
S
M
E
L
L
L
A
G
C
T
T
T
V
T
H
R
--
F
T
K
--
N
L
R
H
H
V
E
N
A
D
L
L
I
V
A
V
G
K
P
G
F
I
P
G
D
W
I
K
E
G
A
I
V
I
D
V
G
I
------
N
-----
R
L
E
N
G
------
K
-
V
V
G
D
V
V
F
E
D
A
A
K
R
A
S
Y
I
T
P
V
P
G
G
V
G
P
M
T
V
A
T
L
I
E
N
T
L
Q
A
C
V
E
Y
H
D
----
2
PsiBlast_PDB
86.65
67%
-116
- C7 -
1B0A
-
FOLD_ECOLI
A:
[2-284]
-
A
A
K
I
I
D
G
K
T
I
A
Q
Q
V
R
S
E
V
A
Q
K
V
Q
--
A
R
-----
I
A
-
A
-
G
L
R
A
P
G
----
L
A
V
V
L
V
G
S
N
P
A
S
Q
I
Y
V
A
S
K
R
K
A
C
E
E
V
G
F
V
S
--
R
S
Y
D
L
P
E
T
T
S
E
A
E
L
L
E
L
I
D
T
L
N
A
D
N
T
I
D
G
I
L
V
Q
L
P
L
P
A
--
G
--
I
D
N
V
K
V
L
E
R
I
H
P
D
K
D
V
D
G
F
H
P
Y
N
V
G
R
L
--
C
--
Q
--
R
-
A
--
P
R
-
L
R
P
C
T
P
R
G
I
V
T
L
L
E
R
Y
N
I
D
T
F
G
L
---
N
A
V
V
I
G
A
S
N
I
V
G
R
P
M
S
M
E
L
L
L
A
G
C
T
T
T
V
T
H
R
--
F
T
K
--
N
L
R
H
H
V
E
N
A
D
L
L
I
V
A
V
G
K
P
G
F
I
P
G
D
W
I
K
E
G
A
I
V
I
D
V
G
I
------
N
-----
R
L
E
N
G
------
K
-
V
V
G
D
V
V
F
E
D
A
A
K
R
A
S
Y
I
T
P
V
P
G
G
V
G
P
M
T
V
A
T
L
I
E
N
T
L
Q
A
C
V
E
Y
H
D
----
83
Fugue
86.33
66%
-116
- C7 -
1B0A
-
FOLD_ECOLI
A:
[2-288]
-
A
A
K
I
I
D
G
K
T
I
A
Q
Q
V
R
S
E
V
A
Q
K
V
Q
--
A
R
-----
I
A
-
A
-
G
L
R
A
P
G
----
L
A
V
V
L
V
G
S
N
P
A
S
Q
I
Y
V
A
S
K
R
K
A
C
E
E
V
G
F
V
S
--
R
S
Y
D
L
P
E
T
T
S
E
A
E
L
L
E
L
I
D
T
L
N
A
D
N
T
I
D
G
I
L
V
Q
L
P
L
P
A
---G-
I
D
N
V
K
V
L
E
R
I
H
P
D
K
D
V
D
G
F
H
P
Y
N
V
G
R
L
--
C
Q
R
A
--
P
-----
R
-
L
R
P
C
T
P
R
G
I
V
T
L
L
E
R
Y
N
I
D
T
F
G
L
---
N
A
V
V
I
G
A
S
N
I
V
G
R
P
M
S
M
E
L
L
L
A
G
C
T
T
T
V
T
H
R
--
F
T
K
--
N
L
R
H
H
V
E
N
A
D
L
L
I
V
A
V
G
K
P
G
F
I
P
G
D
W
I
K
E
G
A
I
V
I
D
V
G
I
------
N
-----
R
L
E
N
G
------
K
-
V
V
G
D
V
V
F
E
D
A
A
K
R
A
S
Y
I
T
P
V
P
G
G
V
G
P
M
T
V
A
T
L
I
E
N
T
L
Q
A
C
V
E
Y
H
D
PQDE
21
PsiBlast_CBE
81.35
50%
-119
- C7 -
3L07
4
FOLD_FRATT
B:
[6-284]
----
L
I
D
G
K
S
L
S
K
D
L
K
E
R
L
A
T
Q
V
Q
--
E
Y
-----
K
H
-
H
-
T
A
I
T
P
K
----
L
V
A
I
I
V
G
N
D
P
A
S
K
T
Y
V
A
S
K
E
K
A
C
A
Q
V
G
I
D
S
--
Q
V
I
T
L
P
E
H
T
T
E
S
E
L
L
E
L
I
D
Q
L
N
N
D
S
S
V
H
A
I
L
V
Q
L
P
L
P
A
--
H
--
I
N
K
N
N
V
I
Y
S
I
K
P
E
K
D
V
D
G
F
H
P
T
N
V
G
R
L
--
Q
--
L
--
R
D
K
--
K
C
-
L
E
S
C
T
P
K
G
I
M
T
M
L
R
E
Y
G
I
K
T
E
G
A
---
Y
A
V
V
V
G
A
S
N
V
V
G
K
P
V
S
Q
L
L
L
N
A
K
A
T
V
T
T
C
H
R
--
F
T
T
--
D
L
K
S
H
T
T
K
A
D
I
L
I
V
A
V
G
K
P
N
F
I
T
A
D
M
V
K
E
G
A
V
V
I
D
V
G
I
------
N
------
H
V
D
G
------
K
-
I
V
G
D
V
D
F
A
A
V
K
D
K
V
A
A
I
T
P
V
P
G
G
V
G
P
M
T
I
T
E
L
L
Y
N
T
F
Q
C
A
Q
E
L
N
R
----
66
HHSearch
81.15
50%
-117
- C7 -
3L07
4
FOLD_FRATT
A:
[3-284]
-
A
M
I
L
I
D
G
K
S
L
S
K
D
L
K
E
R
L
A
T
Q
V
Q
--
E
Y
-----
K
H
-
H
-
T
A
I
T
P
K
----
L
V
A
I
I
V
G
N
D
P
A
S
K
T
Y
V
A
S
K
E
K
A
C
A
Q
V
G
I
D
S
--
Q
V
I
T
L
P
E
H
T
T
E
S
E
L
L
E
L
I
D
Q
L
N
N
D
S
S
V
H
A
I
L
V
Q
L
P
L
P
A
--
H
--
I
N
K
N
N
V
I
Y
S
I
K
P
E
K
D
V
D
G
F
H
P
T
N
V
G
R
L
--
Q
--
L
--
R
-
D
K-
K
C
-
L
E
S
C
T
P
K
G
I
M
T
M
L
R
E
Y
G
I
K
T
E
G
A
---
Y
A
V
V
V
G
A
S
N
V
V
G
K
P
V
S
Q
L
L
L
N
A
K
A
T
V
T
T
C
H
R
--
F
T
T
--
D
L
K
S
H
T
T
K
A
D
I
L
I
V
A
V
G
K
P
N
F
I
T
A
D
M
V
K
E
G
A
V
V
I
D
V
G
I
------
N
-----
H
V
D
-
G
------
K
-
I
V
G
D
V
D
F
A
A
V
K
D
K
V
A
A
I
T
P
V
P
G
G
V
G
P
M
T
I
T
E
L
L
Y
N
T
F
Q
C
A
Q
E
L
N
-----
22
PsiBlast_CBE
81.13
50%
-121
- C7 -
4A26
1
?
B:
[6-292]
--
A
Q
I
I
D
G
K
A
I
A
A
A
I
R
S
E
L
K
D
K
V
A
--
A
L
-----
R
E
L
Y
-
G
G
R
V
P
G
----
L
A
S
I
I
V
G
Q
R
M
D
S
K
K
Y
V
Q
L
K
H
K
A
A
A
E
V
G
M
A
S
--
F
N
V
E
L
P
E
D
I
S
Q
E
V
L
E
V
N
V
E
K
L
N
N
D
P
N
C
H
G
I
I
V
Q
L
P
L
P
K
--
H
--
L
N
E
N
R
A
I
E
K
I
H
P
H
K
D
A
D
A
L
L
P
V
N
V
G
L
L
H
Y
K
--
G
--
R
-
E
--
P
P
-
F
T
P
C
T
A
K
G
V
I
V
L
L
K
R
C
G
I
E
M
A
G
K
---
R
A
V
V
L
G
R
S
N
I
V
G
A
P
V
A
A
L
L
M
K
E
N
A
T
V
T
I
V
H
S
GT
S
T
E
--
D
M
I
D
Y
L
R
T
A
D
I
V
I
A
A
M
G
Q
P
G
Y
V
K
G
E
W
I
K
E
G
A
A
V
V
D
V
G
T
T
P
V
PDP
S
--------
G
Y
------
R
-
L
V
G
D
V
C
F
E
E
A
A
A
R
A
A
W
I
S
P
V
P
G
G
V
G
P
M
T
I
A
M
L
L
E
N
T
L
E
A
F
K
A
A
L
G
----
4
PsiBlast_PDB
81.03
50%
-118
- C7 -
3P2O
2
FOLD_CAMJE
A:
[6-282]
----
L
L
D
G
K
A
L
S
A
K
I
K
E
E
L
K
E
K
N
Q
--
F
L
-----
K
S
-
K
-
G
I
E
-
S
C
----
L
A
V
I
L
V
G
D
N
P
A
S
Q
T
Y
V
K
S
K
A
K
A
C
E
E
C
G
I
K
S
--
L
V
Y
H
L
N
E
N
I
T
Q
N
E
L
L
A
L
I
N
T
L
N
H
D
D
S
V
H
G
I
L
V
Q
L
P
L
P
D
--
H
--
I
C
K
D
L
I
L
E
S
I
I
S
S
K
D
V
D
G
F
H
P
I
N
V
G
Y
L
--
N
--
L
--
G
-
L
--
E
S
G
F
L
P
C
T
P
L
G
V
M
K
L
L
K
A
Y
E
I
D
L
E
G
K
---
D
A
V
I
I
G
A
S
N
I
V
G
R
P
M
A
T
M
L
L
N
A
G
A
T
V
S
V
C
H
I
--
K
T
K
--
D
L
S
L
Y
T
R
Q
A
D
L
I
I
V
A
A
G
C
V
N
L
L
R
S
D
M
V
K
E
G
V
I
V
V
D
V
G
I
------
N
-----
R
L
E
S
G
------
K
-
I
V
G
D
V
D
F
E
E
V
S
K
K
S
S
Y
I
T
P
V
P
G
G
V
G
P
M
T
I
A
M
L
L
E
N
T
V
K
S
A
K
N
R
L
-----
64
HHSearch
80.98
50%
-116
* C7 *
3P2O
2
FOLD_CAMJE
A:
[2-284]
N
A
M
T
L
L
D
G
K
A
L
S
A
K
I
K
E
E
L
K
E
K
N
Q
--
F
L
-----
K
S
---
K
G
I
E
S
C
----
L
A
V
I
L
V
G
D
N
P
A
S
Q
T
Y
V
K
S
K
A
K
A
C
E
E
C
G
I
K
S
--
L
V
Y
H
L
N
E
N
I
T
Q
N
E
L
L
A
L
I
N
T
L
N
H
D
D
S
V
H
G
I
L
V
Q
L
P
L
P
D
--
H
--
I
C
K
D
L
I
L
E
S
I
I
S
S
K
D
V
D
G
F
H
P
I
N
V
G
Y
L
--
N
--
L
--
G
-
L
E-
S
G
-
F
L
P
C
T
P
L
G
V
M
K
L
L
K
A
Y
E
I
D
L
E
G
K
---
D
A
V
I
I
G
A
S
N
I
V
G
R
P
M
A
T
M
L
L
N
A
G
A
T
V
S
V
C
H
I
--
K
T
K
--
D
L
S
L
Y
T
R
Q
A
D
L
I
I
V
A
A
G
C
V
N
L
L
R
S
D
M
V
K
E
G
V
I
V
V
D
V
G
I
------
N
-----
R
L
E
S
G
------
K
-
I
V
G
D
V
D
F
E
E
V
S
K
K
S
S
Y
I
T
P
V
P
G
G
V
G
P
M
T
I
A
M
L
L
E
N
T
V
K
S
A
K
N
R
L
-----
3
PsiBlast_PDB
80.82
50%
-118
- C7 -
3L07
4
FOLD_FRATT
A:
[6-284]
----
L
I
D
G
K
S
L
S
K
D
L
K
E
R
L
A
T
Q
V
Q
--
E
Y
-----
K
H
-
H
-
T
A
I
T
P
K
----
L
V
A
I
I
V
G
N
D
P
A
S
K
T
Y
V
A
S
K
E
K
A
C
A
Q
V
G
I
D
S
--
Q
V
I
T
L
P
E
H
T
T
E
S
E
L
L
E
L
I
D
Q
L
N
N
D
S
S
V
H
A
I
L
V
Q
L
P
L
P
A
--
H
--
I
N
K
N
N
V
I
Y
S
I
K
P
E
K
D
V
D
G
F
H
P
T
N
V
G
R
L
--
Q
--
L
--
R
D
K
--
K
C
-
L
E
S
C
T
P
K
G
I
M
T
M
L
R
E
Y
G
I
K
T
E
G
A
---
Y
A
V
V
V
G
A
S
N
V
V
G
K
P
V
S
Q
L
L
L
N
A
K
A
T
V
T
T
C
H
R
--
F
T
T
--
D
L
K
S
H
T
T
K
A
D
I
L
I
V
A
V
G
K
P
N
F
I
T
A
D
M
V
K
E
G
A
V
V
I
D
V
G
I
------
N
------
H
V
D
G
------
K
-
I
V
G
D
V
D
F
A
A
V
K
D
K
V
A
A
I
T
P
V
P
G
G
V
G
P
M
T
I
T
E
L
L
Y
N
T
F
Q
C
A
Q
E
L
N
-----
5
PsiBlast_PDB
80.77
50%
-119
- C7 -
4A26
1
?
A:
[5-292]
-
S
A
Q
I
I
D
G
K
A
I
A
A
A
I
R
S
E
L
K
D
K
V
A
--
A
L
-----
R
E
L
Y
-
G
G
R
V
P
G
----
L
A
S
I
I
V
G
Q
R
M
D
S
K
K
Y
V
Q
L
K
H
K
A
A
A
E
V
G
M
A
S
--
F
N
V
E
L
P
E
D
I
S
Q
E
V
L
E
V
N
V
E
K
L
N
N
D
P
N
C
H
G
I
I
V
Q
L
P
L
P
K
--
H
--
L
N
E
N
R
A
I
E
K
I
H
P
H
K
D
A
D
A
L
L
P
V
N
V
G
L
L
H
Y
K
--
G
--
R
-
E
--
P
P
-
F
T
P
C
T
A
K
G
V
I
V
L
L
K
R
C
G
I
E
M
A
G
K
---
R
A
V
V
L
G
R
S
N
I
V
G
A
P
V
A
A
L
L
M
K
E
N
A
T
V
T
I
V
H
S
GT
S
T
E
--
D
M
I
D
Y
L
R
T
A
D
I
V
I
A
A
M
G
Q
P
G
Y
V
K
G
E
W
I
K
E
G
A
A
V
V
D
V
G
T
T
P
V
PDP
S
-----
R
K
D
G
Y
------
R
-
L
V
G
D
V
C
F
E
E
A
A
A
R
A
A
W
I
S
P
V
P
G
G
V
G
P
M
T
I
A
M
L
L
E
N
T
L
E
A
F
K
A
A
L
G
----
6
PsiBlast_PDB
79.42
46%
-118
- C7 -
4CJX
4
?
A:
[25-309]
--
A
V
V
I
D
G
R
A
V
A
K
A
I
Q
K
E
L
T
E
E
V
A
L
L
E
R
-----
R
Y
-
K
-
G
R
R
-
P
G
----
L
S
T
I
I
C
G
K
R
K
D
S
Q
T
Y
V
R
L
K
R
K
A
A
A
A
C
G
F
R
N
--
F
S
V
E
L
P
A
N
V
T
Q
E
A
L
E
R
E
V
I
R
L
N
E
E
E
A
C
H
S
I
V
V
Q
L
P
L
P
P
--
H
--
I
D
K
V
A
A
L
S
K
I
K
P
E
K
D
A
D
C
L
L
P
V
N
V
G
Q
L
HI
R
--
E
--
R
-
N
--
P
A
-
I
V
P
C
T
A
S
A
V
M
E
L
L
R
C
S
G
V
E
I
C
G
K
---
R
V
V
V
L
G
R
G
D
I
A
G
L
P
V
A
T
L
L
A
N
E
D
A
T
V
T
V
V
H
S
--
A
T
P
L
C
D
I
A
D
I
V
R
A
S
D
I
V
V
S
A
A
G
Q
P
G
L
V
R
G
E
W
I
K
L
G
A
A
V
I
D
V
G
T
------
T
-----
P
V
A
D
P
SKVPG
Y
R
-
L
V
G
D
V
C
F
D
V
A
R
K
R
A
A
Y
I
T
P
V
P
G
G
V
G
P
V
T
V
S
M
L
L
K
N
T
L
T
M
F
K
R
S
V
R
----
14
PsiBlast_PDB
79.26
42%
-118
- C7 -
4B4V
4
?
A:
[23-299]
--
A
L
V
L
D
G
R
A
L
A
K
Q
I
E
E
N
L
L
V
R
V
E
--
A
L
-----
K
A
-
K
-
T
G
R
T
P
I
----
L
A
T
I
L
V
G
D
D
G
A
S
A
T
Y
V
R
M
K
G
N
A
C
R
R
V
G
M
D
S
--
L
K
I
E
L
P
Q
E
T
T
T
E
Q
L
L
A
E
I
E
K
L
N
A
N
P
D
V
H
G
I
L
L
Q
H
P
V
P
A
--
Q
--
I
D
E
R
A
C
F
D
A
I
S
L
A
K
D
V
D
G
V
T
C
L
G
F
G
R
M
--
A
--
M
--
G
-
E
--
A
A
-
Y
G
S
A
T
P
A
G
I
M
T
I
L
K
E
N
N
I
E
I
A
G
K
---
H
A
V
V
V
G
R
S
A
I
L
G
K
P
M
A
M
M
L
L
Q
A
N
A
T
V
T
I
C
H
S
--
R
T
Q
--
N
L
P
E
L
V
K
Q
A
D
I
I
V
G
A
V
G
K
A
E
L
I
Q
K
D
W
I
K
Q
G
A
V
V
V
D
A
G
F
------
H
-----
P
R
-
D
G
------
G
-
G
V
G
D
I
Q
L
Q
G
I
E
E
I
A
S
A
Y
T
P
V
P
G
G
V
G
P
M
T
I
T
T
L
I
R
Q
T
V
E
A
A
E
K
A
L
G
----
23
PsiBlast_CBE
79.19
46%
-118
- C7 -
4CJX
2
?
B:
[25-309]
--
A
V
V
I
D
G
R
A
V
A
K
A
I
Q
K
E
L
T
E
E
V
A
LL
E
R
-----
R
Y
-
K
-
G
R
R
-
P
G
----
L
S
T
I
I
C
G
K
R
K
D
S
Q
T
Y
V
R
L
K
R
K
A
A
A
A
C
G
F
R
N
--
F
S
V
E
L
P
A
N
V
T
Q
E
A
L
E
R
E
V
I
R
L
N
E
E
E
A
C
H
S
I
V
V
Q
L
P
L
P
P
--
H
--
I
D
K
V
A
A
L
S
K
I
K
P
E
K
D
A
D
C
L
L
P
V
N
V
G
Q
L
HI
R
--
E
--
R
-
N
--
P
A
-
I
V
P
C
T
A
S
A
V
M
E
L
L
R
C
S
G
V
E
I
C
G
K
---
R
V
V
V
L
G
R
G
D
I
A
G
L
P
V
A
T
L
L
A
N
E
D
A
T
V
T
V
V
H
S
--
A
T
P
LC
D
I
A
D
I
V
R
A
S
D
I
V
V
S
A
A
G
Q
P
G
L
V
R
G
E
W
I
K
L
G
A
A
V
I
D
V
G
T
------
T
-----
P
V
A
D
P
SKVPGY
R
-
L
V
G
D
V
C
F
D
V
A
R
K
R
A
A
Y
I
T
P
V
P
G
G
V
G
P
V
T
V
S
M
L
L
K
N
T
L
T
M
F
K
R
S
V
R
----
30
PsiBlast_CBE
79.00
42%
-116
- C7 -
4B4U
7
?
B:
[23-299]
--
A
L
V
L
D
G
R
A
L
A
K
Q
I
E
E
N
L
L
V
R
V
E
--
A
L
-----
K
A
-
K
-
T
G
R
T
P
I
----
L
A
T
I
L
V
G
D
D
G
A
S
A
T
Y
V
R
M
K
G
N
A
C
R
R
V
G
M
D
S
--
L
K
I
E
L
P
Q
E
T
T
T
E
Q
L
L
A
E
I
E
K
L
N
A
N
P
D
V
H
G
I
L
L
Q
H
P
V
P
A
--
Q
--
I
D
E
R
A
C
F
D
A
I
S
L
A
K
D
V
D
G
V
T
C
L
G
F
G
R
M
--
A
--
M
--
G
-
E
--
A
A
-
Y
G
S
A
T
P
A
G
I
M
T
I
L
K
E
N
N
I
E
I
A
G
K
---
H
A
V
V
V
G
R
S
A
I
L
G
K
P
M
A
M
M
L
L
Q
A
N
A
T
V
T
I
C
H
S
--
R
T
Q
--
N
L
P
E
L
V
K
Q
A
D
I
I
V
G
A
V
G
K
A
E
L
I
Q
K
D
W
I
K
Q
G
A
V
V
V
D
A
G
F
------
H
-----
P
R
-
D
G
------
G
-
G
V
G
D
I
Q
L
Q
G
I
E
E
I
A
S
A
Y
T
P
V
P
G
G
V
G
P
M
T
I
T
T
L
I
R
Q
T
V
E
A
A
E
K
A
L
G
----
13
PsiBlast_PDB
78.61
42%
-115
- C7 -
4B4U
9
?
A:
[23-299]
--
A
L
V
L
D
G
R
A
L
A
K
Q
I
E
E
N
L
L
V
R
V
E
--
A
L
-----
K
A
-
K
-
T
G
R
T
P
I
----
L
A
T
I
L
V
G
D
D
G
A
S
A
T
Y
V
R
M
K
G
N
A
C
R
R
V
G
M
D
S
--
L
K
I
E
L
P
Q
E
T
T
T
E
Q
L
L
A
E
I
E
K
L
N
A
N
P
D
V
H
G
I
L
L
Q
H
P
V
P
A
--
Q
--
I
D
E
R
A
C
F
D
A
I
S
L
A
K
D
V
D
G
V
T
C
L
G
F
G
R
M
--
A
--
M
--
G
-
E
--
A
A
-
Y
G
S
A
T
P
A
G
I
M
T
I
L
K
E
N
N
I
E
I
A
G
K
---
H
A
V
V
V
G
R
S
A
I
L
G
K
P
M
A
M
M
L
L
Q
A
N
A
T
V
T
I
C
H
S
--
R
T
Q
--
N
L
P
E
L
V
K
Q
A
D
I
I
V
G
A
V
G
K
A
E
L
I
Q
K
D
W
I
K
Q
G
A
V
V
V
D
A
G
F
------
H
-----
P
R
-
D
G
------
G
-
G
V
G
D
I
Q
L
Q
G
I
E
E
I
A
S
A
Y
T
P
V
P
G
G
V
G
P
M
T
I
T
T
L
I
R
Q
T
V
E
A
A
E
K
A
L
G
----
29
PsiBlast_CBE
78.48
42%
-115
- C7 -
4B4V
3
?
B:
[23-299]
--
A
L
V
L
D
G
R
A
L
A
K
Q
I
E
E
N
L
L
V
R
V
E
--
A
L
-----
K
A
-
K
-
T
G
R
T
P
I
----
L
A
T
I
L
V
G
D
D
G
A
S
A
T
Y
V
R
M
K
G
N
A
C
R
R
V
G
M
D
S
--
L
K
I
E
L
P
Q
E
T
T
T
E
Q
L
L
A
E
I
E
K
L
N
A
N
P
D
V
H
G
I
L
L
Q
H
P
V
P
A
--
Q
--
I
D
E
R
A
C
F
D
A
I
S
L
A
K
D
V
D
G
V
T
C
L
G
F
G
R
M
--
A
--
M
--
G
-
E
--
A
A
-
Y
G
S
A
T
P
A
G
I
M
T
I
L
K
E
N
N
I
E
I
A
G
K
---
H
A
V
V
V
G
R
S
A
I
L
G
K
P
M
A
M
M
L
L
Q
A
N
A
T
V
T
I
C
H
S
--
R
T
Q
--
N
L
P
E
L
V
K
Q
A
D
I
I
V
G
A
V
G
K
A
E
L
I
Q
K
D
W
I
K
Q
G
A
V
V
V
D
A
G
F
------
H
-----
P
R
-
D
G
------
G
-
G
V
G
D
I
Q
L
Q
G
I
E
E
I
A
S
A
Y
T
P
V
P
G
G
V
G
P
M
T
I
T
T
L
I
R
Q
T
V
E
A
A
E
K
A
L
G
----
15
PsiBlast_PDB
77.86
42%
-113
- C7 -
4B4W
4
?
A:
[23-299]
--
A
L
V
L
D
G
R
A
L
A
K
Q
I
E
E
N
L
L
V
R
V
E
--
A
L
-----
K
A
-
K
-
T
G
R
T
P
I
----
L
A
T
I
L
V
G
D
D
G
A
S
A
T
Y
V
R
M
K
G
N
A
C
R
R
V
G
M
D
S
--
L
K
I
E
L
P
Q
E
T
T
T
E
Q
L
L
A
E
I
E
K
L
N
A
N
P
D
V
H
G
I
L
L
Q
H
P
V
P
A
--
Q
--
I
D
E
R
A
C
F
D
A
I
S
L
A
K
D
V
D
G
V
T
C
L
G
F
G
R
M
--
A
--
M
--
G
-
E
--
A
A
-
Y
G
S
A
T
P
A
G
I
M
T
I
L
K
E
N
N
I
E
I
A
G
K
---
H
A
V
V
V
G
R
S
A
I
L
G
K
P
M
A
M
M
L
L
Q
A
N
A
T
V
T
I
C
H
S
--
R
T
Q
--
N
L
P
E
L
V
K
Q
A
D
I
I
V
G
A
V
G
K
A
E
L
I
Q
K
D
W
I
K
Q
G
A
V
V
V
D
A
G
F
------
H
-----
P
R
-
D
G
------
G
-
G
V
G
D
I
Q
L
Q
G
I
E
E
I
A
S
A
Y
T
P
V
P
G
G
V
G
P
M
T
I
T
T
L
I
R
Q
T
V
E
A
A
E
K
A
L
G
----
10
PsiBlast_PDB
77.54
43%
-118
- C7 -
1A4I
1
C1TC_HUMAN
A:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
F
T
P
R
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
Y----------------K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
28
PsiBlast_CBE
77.49
42%
-114
- C7 -
4B4W
3
?
B:
[23-299]
--
A
L
V
L
D
G
R
A
L
A
K
Q
I
E
E
N
L
L
V
R
V
E
--
A
L
-----
K
A
-
K
-
T
G
R
T
P
I
----
L
A
T
I
L
V
G
D
D
G
A
S
A
T
Y
V
R
M
K
G
N
A
C
R
R
V
G
M
D
S
--
L
K
I
E
L
P
Q
E
T
T
T
E
Q
L
L
A
E
I
E
K
L
N
A
N
P
D
V
H
G
I
L
L
Q
H
P
V
P
A
--
Q
--
I
D
E
R
A
C
F
D
A
I
S
L
A
K
D
V
D
G
V
T
C
L
G
F
G
R
M
--
A
--
M
--
G
-
E
--
A
A
-
Y
G
S
A
T
P
A
G
I
M
T
I
L
K
E
N
N
I
E
I
A
G
K
---
H
A
V
V
V
G
R
S
A
I
L
G
K
P
M
A
M
M
L
L
Q
A
N
A
T
V
T
I
C
H
S
--
R
T
Q
--
N
L
P
E
L
V
K
Q
A
D
I
I
V
G
A
V
G
K
A
E
L
I
Q
K
D
W
I
K
Q
G
A
V
V
V
D
A
G
F
------
H
-----
P
R
-
D
G
------
G
-
G
V
G
D
I
Q
L
Q
G
I
E
E
I
A
S
A
Y
T
P
V
P
G
G
V
G
P
M
T
I
T
T
L
I
R
Q
T
V
E
A
A
E
K
A
L
G
----
25
PsiBlast_CBE
77.30
43%
-122
- C7 -
1DIB
1
C1TC_HUMAN
B:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
FTPR
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
YVPDD
K
K
P
N
G
------
R
K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
65
HHSearch
77.24
44%
-112
- C7 -
1A4I
1
C1TC_HUMAN
A:
[2-295]
A
P
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
V
P
G
F
T
P
R
----
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
EN
S
--
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
--
G
-
D
LN
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
-----
Y
----------
K
-
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
7
PsiBlast_PDB
77.12
43%
-121
- C7 -
1DIA
2
C1TC_HUMAN
A:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
F
T
P
R
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
Y----------------K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
27
PsiBlast_CBE
76.61
43%
-117
- C7 -
1A4I
1
C1TC_HUMAN
B:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
FTPR
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
YVPDD
K
K
P
N
G
------
R
K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
9
PsiBlast_PDB
76.39
43%
-121
- C7 -
1DIG
2
C1TC_HUMAN
A:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
F
T
P
R
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
Y----------------K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
26
PsiBlast_CBE
76.03
43%
-118
- C7 -
1DIA
1
C1TC_HUMAN
B:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
FTPR
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
YVPDD
K
K
P
N
G
------
R
K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
8
PsiBlast_PDB
75.90
43%
-117
- C7 -
1DIB
2
C1TC_HUMAN
A:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
F
T
P
R
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
Y----------------K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
24
PsiBlast_CBE
75.65
43%
-120
- C7 -
1DIG
2
C1TC_HUMAN
B:
[4-294]
--
A
E
I
L
N
G
K
E
I
S
A
Q
I
R
A
R
L
K
N
Q
V
T
--
Q
L
-----
K
E
-
Q
----
V
P
G
FTPR
L
A
I
L
Q
V
G
N
R
D
D
S
N
L
Y
I
N
V
K
L
K
A
A
E
E
I
G
I
K
A
--
T
H
I
K
L
P
R
T
T
T
E
S
E
V
M
K
Y
I
T
S
L
N
E
D
S
T
V
H
G
F
L
V
Q
L
P
L
D
S
--
E
NS
I
N
T
E
E
V
I
N
A
I
A
P
E
K
D
V
D
G
L
T
S
I
N
A
G
R
L
--
A
--
R
GD
L
-
N
--
D
C
-
F
I
P
C
T
P
K
G
C
L
E
L
I
K
E
T
G
V
P
I
A
G
R
---
H
A
V
V
V
G
R
S
K
I
V
G
A
P
M
H
D
L
L
L
W
N
N
A
T
V
T
T
C
H
S
--
K
T
A
--
H
L
D
E
E
V
N
K
G
D
I
L
V
V
A
T
G
Q
P
E
M
V
K
G
E
W
I
K
P
G
A
I
V
I
D
C
G
I
------
N
YVPDD
K
K
P
N
G
------
R
K
V
V
G
D
V
A
Y
D
E
A
K
E
R
A
S
F
I
T
P
V
P
G
G
V
G
P
M
T
V
A
M
L
M
Q
S
T
V
E
S
A
K
R
F
L
E
----
16
PsiBlast_PDB
70.47
36%
-118
- C7 -
3NGL
1
FOLD_THEAC
A:
[7-271]
----------------
E
E
I
A
E
K
K
A
--
E
N
L
H
G
I
I
E
R
-
S
-
G
L
E
-
P
S
----
L
K
L
I
Q
I
G
D
N
E
A
A
S
I
Y
A
R
A
K
I
R
R
G
K
K
I
G
I
A
V
D
L
E
K
Y
D
---
D
I
S
M
K
D
L
L
K
R
I
D
D
L
A
K
D
P
Q
I
N
G
I
M
I
E
N
P
L
P
K
--
G
--
F
D
Y
Y
E
I
V
R
N
I
P
Y
Y
K
D
V
D
A
L
S
P
Y
N
Q
G
L
I
--
A
--
L
--
N
-
R
--
E
F
-
L
V
P
A
T
P
R
A
V
I
D
I
M
-----
D
Y
Y
G
Y
HE
N
T
V
T
I
V
N
R
S
P
V
V
G
R
P
L
S
M
M
L
L
N
R
N
Y
T
V
S
V
C
H
S
--
K
T
K
--
D
I
G
S
M
T
R
S
S
K
I
V
V
V
A
V
G
R
P
G
F
L
N
R
E
M
V
T
P
G
S
V
V
I
D
V
G
I
------
N
-----
Y
V
N
D
-------
K
-
V
V
G
D
A
N
F
E
D
L
S
E
Y
V
E
A
I
T
P
V
P
G
G
V
G
P
I
T
A
T
N
I
L
E
N
V
V
K
A
A
E
F
Q
K
N
----
31
PsiBlast_CBE
69.28
36%
-117
- C7 -
3NGL
1
FOLD_THEAC
C:
[7-271]
----------------
E
E
I
A
E
K
K
A
--
E
N
LHGII
E
R
-
S
-
G
L
E
-
P
S
----
L
K
L
I
Q
I
G
D
N
E
A
A
S
I
Y
A
R
A
K
I
R
R
G
K
K
I
G
I
A
V
DL
E
K
Y
D
---
D
I
S
M
K
D
L
L
K
R
I
D
D
L
A
K
D
P
Q
I
N
G
I
M
I
E
N
P
L
P
K
--
G
--
F
D
Y
Y
E
I
V
R
N
I
P
Y
Y
K
D
V
D
A
L
S
P
Y
N
Q
G
L
I
--
A
--
L
--
N
-
R
--
E
F
-
L
V
P
A
T
P
R
A
V
I
D
I
M
-----
D
Y
Y
G
Y
HEN
T
V
T
I
V
N
R
S
P
V
V
G
R
P
L
S
M
M
L
L
N
R
N
Y
T
V
S
V
C
H
S
--
K
T
K
--
D
I
G
S
M
T
R
S
S
K
I
V
V
V
A
V
G
R
P
G
F
L
N
R
E
M
V
T
P
G
S
V
V
I
D
V
G
I
------
N
-----
Y
V
N
D
-------
K
-
V
V
G
D
A
N
F
E
D
L
S
E
Y
V
E
A
I
T
P
V
P
G
G
V
G
P
I
T
A
T
N
I
L
E
N
V
V
K
A
A
E
F
Q
K
N
----