@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA2294: (2016-02-06 )
MTTAGNSLGRIQIRDLSIRLGQGSEAFEAVRDLNLEARPGEFVCLLGPSGCGKSTLLGALAGHLRPSAGSVRVDGRSVEGPSPQRGMVFQQHTLFPWRRVRDNVAFGLKMQGLARAERNRRAMEMLGLVGLADFAGRWPGQLSGGMQQRVEIARVLVNRPRLLLMDEPFGALDAQTRLKMQTLLLDVWARVRTTVLFVTHDIDEALYLADRVLVMSPRPGRIIADLALDFPRPRDTRLVTSADFVRLKRHCLELLDHDDGRQLPRLTPLGLPPGITPDRLRIAI
Atome Classification :
(37 SA)
.........10........20...-.-...---.30........40........50........60........70....-------...-.80--..-------...---------....90-.-........100.....-.--.110-...--....120..-.....130-.-......140.......150.......160.......170.......180.......190.---......200...------....210.......220.......--230.......240-.........250.......260.......270.........280..--------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTTAGNS
L
G
R
I
Q
I
R
D
L
S
I
RLGQG
S
-
E
-
A
F
E
---
A
V
R
DLNLEARPG
E
F
V
C
L
LGPSGC
G
K
S
T
L
L
G
A
L
A
G
HLRPSA
G
S
V
R
VDG-------RSV-EG---PS-------PQR---------
G
M
V
F
Q--Q-HTL
F
P
W
R
R
V
RDNVAF
G
-
L
--
K
M
Q
G
-
L
A
R
--
A
E
R
N
R
R
A
M
E
-
M
L
G
L
V
G
L
A
-
D
-
F
A
GRWPGQLSG
G
M
Q
Q
R
V
E
I
A
R
V
L
VNRP
R
L
L
L
MDEPFGAL
D
A
Q
T
R
L
K
M
Q
T
L
L
L
D
V
W
A
R
V
R
T
---
T
V
L
F
V
THDI
D
E
A
------
L
Y
L
A
D
R
V
L
V
MSPRP
G
R
I
I
A
D
L
ALD--FPRPRD
T
R
L
V
T
---
S
A
D
F
V
R
L
K
R
H
C
L
E
L
LDHDDGRQLPRLTPLG--LPPGI
T
P
D
R
L
R
IAI--------------------------------------------------------------
63
PsiBlast_CBE
88.63
36%
-126
- C1 -
4U02
1
?
C:
[5-233]
----------
I
R
I
R
N
L
H
K
W
F
G
------
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------
L
S
V
-
K
D
---
D
R
-------
A
L
R
EIRREV---
G
M
V
F
Q
--
Q
-
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
--
R
V
R
R
-
W
P
R
--
E
K
A
E
K
K
A
L
E
-
L
L
E
R
V
G
I
L
-
D
-
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
A
D
R
V
V
F
M
D
--
G
G
Q
I
V
E
E
G
R
P
E
EI
F
T
R
P
K
E
E
R
------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
86.51
36%
-121
- C1 -
4U02
1
?
A:
[5-233]
----------
I
R
I
R
N
L
H
K
W
F
G
------
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------
L
S
V
-
K
D
---
D
R
-------
A
L
R
E
I
R
R
E
V
---
G
M
V
F
Q
--
Q
-
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
--
R
V
R
R
-
W
P
R
--
E
K
A
E
K
K
A
L
E
-
L
L
E
R
V
G
I
L
-
D
-
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
A
D
R
V
V
F
M
D
--
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
86.17
36%
-125
- C1 -
4U00
3
?
A:
[5-233]
----------
I
R
I
R
N
L
H
K
W
F
G
------
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------
L
S
V
-
K
D
---
D
R
-------
A
L
R
E
I
R
R
E
V
---
G
M
V
F
Q
--
Q
-
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
--
R
V
R
R
-
W
P
R
--
E
K
A
E
K
K
A
L
E
-
L
L
E
R
V
G
I
L
-
D
-
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
A
D
R
V
V
F
M
D
--
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
85.61
36%
-120
- C1 -
4U02
1
?
D:
[5-233]
----------
I
R
I
R
N
L
H
K
W
F
G
------
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------
L
S
V
-
K
D
---
D
R
-------
A
L
R
EIRREV---
G
M
V
F
Q
--
Q
-
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
--
R
V
R
R
-
W
P
R
--
E
K
A
E
K
K
A
L
E
-
L
L
E
R
V
G
I
L
-
D
-
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
A
D
R
V
V
F
M
D
--
G
G
Q
I
V
E
E
G
R
P
E
EI
F
T
R
P
K
E
E
R
------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
84.48
40%
-133
- C1 -
2IT1
1
?
B:
[3-213]
---------
E
I
K
L
E
N
I
V
K
K
F
G
N
------
F
T
---
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
-------
K
D
V
T
E
L
---
P
P
-------
K
D
R
N
V
-------
G
L
V
F
Q
--
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
--
E
L
R
K
-
A
P
R
--
E
E
I
D
K
K
V
R
E
-
V
A
K
M
L
H
I
D
-
K
-
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
---
T
T
V
Y
V
T
H
D
Q
A
E
A
------
L
A
M
A
D
R
I
A
V
I
--
R
E
G
E
I
L
----------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.68
40%
-129
- C1 -
2IT1
-
?
A:
[3-213]
---------
E
I
K
L
E
N
I
V
K
K
F
G
N
------
F
T
---
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
-------
K
D
V
T
E
L
---
P
P
-------
K
D
R
N
V
-------
G
L
V
F
Q
--
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
--
E
L
R
K
-
A
P
R
--
E
E
I
D
K
K
V
R
E
-
V
A
K
M
L
H
I
D
-
K
-
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
---
T
T
V
Y
V
T
H
D
Q
A
E
A
------
L
A
M
A
D
R
I
A
V
I
--
R
E
G
E
I
L
----------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
83.27
36%
-123
- C1 -
4U02
1
?
B:
[5-233]
----------
I
R
I
R
N
L
H
K
W
F
G
------
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------
L
S
V
-
K
D
---
D
R
-------
A
L
R
EIRREV---
G
M
V
F
Q
--
Q
-
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
--
R
V
R
R
-
W
P
R
--
E
K
A
E
K
K
A
L
E
-
L
L
E
R
V
G
I
L
-
D
-
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
A
D
R
V
V
F
M
D
--
G
G
Q
I
V
E
E
G
R
P
E
EI
F
T
R
P
K
E
E
R
------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
80.04
32%
-108
- C1 -
4HLU
3
ECFA2_THEMA
B:
[3-238]
--------
G
R
I
E
V
V
N
V
S
H
I
F
H
R
G
T
-
P
L
E
K
K
---
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
-------
E
R
K
-
K
G
---
Y
E
-------
I
R
R
NI-------
G
I
A
F
Q
--
Y
P
E
D
Q
F
F
A
E
R
V
F
D
E
V
A
F
A
-
V
--
K
N
F
Y
-
P
D
R
DP
V
P
L
V
K
K
A
M
E
-
F
V
G
L
-
D
F
D
-
S
-
F
K
D
R
V
P
F
F
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
-
I
V
E
K
W
K
T
L
G
K
---
T
V
I
L
I
S
H
D
I
E
T
V
------
I
N
H
V
D
R
V
V
V
L
E
-
K
G
K
K
V
F
D
G
T
R
M
E
--
F
L
E
K
Y
D
P
R
F
F
T
---
S
-----------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
80.04
38%
-142
- C1 -
1V43
-
?
A:
[12-223]
---------
E
V
K
L
E
N
L
T
K
R
F
G
N
------
F
T
---
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
-------
R
D
V
-
T
Y
---
L
P
-------
P
K
D
RN
I
------
S
M
V
F
Q
---------
H
M
T
V
Y
E
N
I
A
F
P
-
L
----
K
K
-
F
P
K
--
D
E
I
D
K
R
V
R
W
-
A
A
E
L
L
Q
I
E
-
E
-
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
------
M
T
M
G
D
R
I
A
V
M
N
-----------------------------------------------------------------------------------------------------------------------------------------
113
HHSearch
79.74
39%
-121
- C1 -
2IT1
-
?
A:
[2-219]
--------
V
E
I
K
L
E
N
I
V
K
K
F
G
------
N
F
T
---
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
-------
K
D
V
-
T
E
LPP
K
D
-------
R
N
V
---------
G
L
V
F
Q
--
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
--
E
L
R
K
-
A
P
R
--
E
E
I
D
K
K
V
R
E
-
V
A
K
M
L
H
I
D
-
K
-
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
---
T
T
V
Y
V
T
H
D
Q
A
E
A
------
L
A
M
A
D
R
I
A
V
I
R
--
E
G
E
I
L
Q
V
G
T
P
D
----------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
79.68
37%
-118
- C1 -
1L2T
4
Y796_METJA
B:
[2-220]
----------
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
-
E
-
I
I
Y
---
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-------
I
K
T
-
N
D
---
L
D
-------
D
D
E
LTKIRRDKI
G
F
V
F
Q
--
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
-
L
IF
K
Y
R
G
A
M
S
G
--
E
E
R
R
K
R
A
L
E
-
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
---
T
V
V
V
V
T
H
D
I
N
V
A
RFGERI
I
Y
L
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------
107
Fugue
79.07
33%
-105
- C1 -
1Z47
1
?
A:
[11-355]
------
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
-
R
-
S
------
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
-------
K
R
V
-
T
D
---
L
P
-------
P
Q
K
RN
V
------
G
L
V
F
Q
--
N
-
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
-
L
--
R
E
K
R
-
V
P
K
--
D
E
M
D
A
R
V
R
E
-
L
L
R
F
M
R
L
E
-
S
-
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
---
T
S
V
F
V
T
H
D
Q
E
E
A
------
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
--
Y
E
K
P
G
T
L
F
V
A
S
F
IG
E
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
D
P
A
V
S
E
G
S
E
V
A
V
V
V
R
P
K
D
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
98
PsiBlast_CBE
78.20
32%
-108
- C1 -
4HLU
2
ECFA2_THEMA
A:
[3-238]
--------
G
R
I
E
V
V
N
V
S
H
I
F
H
R
G
T
-
P
L
E
K
K
---
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
-------
E
R
K
-
K
G
---
Y
E
-------
I
R
R
N
I
-------
G
I
A
F
Q
--
Y
P
E
D
Q
F
F
A
E
R
V
F
D
E
V
A
F
A
-
V
--
K
N
F
Y
-
P
D
R
DP
V
P
L
V
K
K
A
M
E
-
F
V
G
L
-
D
F
D
-
S
-
F
K
D
R
V
P
F
F
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
-
I
V
E
K
W
K
T
L
G
K
---
T
V
I
L
I
S
H
D
I
E
T
V
------
I
N
H
V
D
R
V
V
V
L
E
-
K
G
K
K
V
F
D
G
T
R
M
E
--
F
L
E
K
Y
D
P
R
F
F
T
---
S
-----------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.01
38%
-141
- C1 -
1VCI
1
?
A:
[12-223]
---------
E
V
K
L
E
N
L
T
K
R
F
G
N
------
F
T
---
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
-------
R
D
V
-
T
Y
---
L
P
-------
P
K
D
RN
I
------
S
M
V
F
Q
---------
H
M
T
V
Y
E
N
I
A
F
P
-
L
----
K
K
-
F
P
K
--
D
E
I
D
K
R
V
R
W
-
A
A
E
L
L
Q
I
E
-
E
-
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
------
M
T
M
G
D
R
I
A
V
M
N
-----------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
77.79
36%
-121
- C1 -
3TIF
7
Y796_METJA
B:
[2-220]
----------
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
-
E
-
I
I
Y
---
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-------
I
K
T
-
N
D
---
L
D
-------
D
D
E
LTKIRRDKI
G
F
V
F
Q
--
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
-
L
IF
K
Y
R
G
A
M
S
G
--
E
E
R
R
K
R
A
L
E
-
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
---
T
V
V
V
V
T
H
D
I
N
V
A
RFGERI
I
Y
L
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
77.39
35%
-119
- C1 -
2OUK
1
?
A:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TN
L
N
K
V
R
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
115
HHSearch
77.33
37%
-127
- C1 -
1V43
-
?
A:
[8-234]
-----
I
K
M
V
E
V
K
L
E
N
L
T
K
R
F
G
------
N
F
T
---
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
-------
R
D
V
-
T
Y
LPP
K
D
-------
R
N
I
---------
S
M
V
F
Q
---------
H
M
T
V
Y
E
N
I
A
F
P
-
L
----
K
K
-
F
P
K
--
D
E
I
D
K
R
V
R
W
-
A
A
E
L
L
Q
I
E
-
E
-
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
---
T
T
I
Y
V
T
H
D
Q
V
E
A
------
M
T
M
G
D
R
I
A
V
M
N
--
R
G
Q
L
L
Q
I
G
S
P
T
----------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
76.89
38%
-120
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[4-223]
----------------
A
L
H
I
G
H
L
S
-
K
-
S
F
Q
NTP
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-------
K
T
I
-
F
S
---
K
N
T
N
L
----
P
V
R
ERR
L
-----
G
Y
L
V
Q
--
E
-
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
-
L
--
G
-
N
G
-
K
G
R
--
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
-
E
-
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
---
S
A
V
F
V
S
H
D
R
E
E
A
------
L
Q
Y
A
D
R
I
A
V
M
--
K
Q
G
R
I
L
----------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
76.59
38%
-122
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[4-218]
----------------
A
L
H
I
G
H
L
S
-
K
-
S
F
Q
NTP
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-------
K
T
I
-
F
S
---
K
N
TNL----
P
V
R
ERRL-----
G
Y
L
V
Q
--
E
-
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
-
L
--
G
-
N
G
-
K
G
R
--
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
-
E
-
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
---
S
A
V
F
V
S
H
D
R
E
E
A
------
L
Q
Y
A
D
R
I
A
V
M
--
K
Q
G
R
I
L
----------------------------------------------------------------------------------------------------------------------------------
117
HHSearch
76.57
38%
-127
- C1 -
2YYZ
3
?
A:
[2-219]
--------
P
S
I
R
V
V
N
L
K
K
Y
F
G
------
K
V
K
---
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
-------
V
L
V
-
N
D
IPP
K
Y
-------
R
E
V
---------
G
M
V
F
Q
--
N
-
Y
A
L
Y
P
H
M
T
V
F
E
N
I
A
F
P
-
L
--
R
A
R
R
-
I
S
K
--
D
E
V
E
K
R
V
V
E
-
I
A
R
K
L
L
I
D
-
N
-
L
L
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
---
T
S
V
Y
V
T
H
D
Q
A
E
A
------
M
T
M
A
S
R
I
A
V
F
N
--
Q
G
K
L
V
Q
Y
G
T
P
D
----------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
76.55
35%
-119
- C1 -
3C4J
4
?
B:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
85
PsiBlast_CBE
74.66
35%
-114
- C1 -
2OLK
1
?
C:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
86
PsiBlast_CBE
74.38
35%
-111
- C1 -
2OLK
2
?
B:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
73.59
35%
-114
- C1 -
2Q0H
4
?
A:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TN
L
N
K
V
R
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
73.53
35%
-114
- C1 -
2OLK
1
?
A:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
T
N
L
N
K
V
R
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
73.45
35%
-113
- C1 -
2OLK
1
?
D:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
73.15
35%
-113
- C1 -
3C41
3
?
J:
[15-233]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
71.79
31%
-109
- C1 -
4MKI
4
ECFA2_CALS4
B:
[7-222]
----------
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
-
A
T
V
---
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
IDITDKK
V
S
L
-
K
D
---
I
R
-------
K
Q
V
---------
G
L
V
F
Q
YP
E
-
Y
Q
L
F
E
E
T
V
F
K
D
-
I
A
F
G
-
P
--
S
N
L
G
-
L
S
E
--
E
E
V
K
E
R
V
Y
E
-
A
M
E
I
V
G
I
S
K
E
-
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
Y
K
M
---
I
T
I
L
V
S
H
N
M
E
D
I
------
A
R
I
A
D
K
I
I
V
M
N
-----------------------------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
71.64
35%
-119
- C1 -
2OLJ
4
?
A:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TN
L
N
K
V
R
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
71.10
35%
-113
- C1 -
3C41
3
?
K:
[15-233]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
70.74
35%
-115
- C1 -
3C4J
3
?
A:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TN
L
N
K
V
R
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
69.91
35%
-113
- C1 -
2OLJ
3
?
B:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNLNKVR
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
DL
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
68.64
35%
-114
- C1 -
2Q0H
4
?
B:
[36-254]
---------------------------
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------
I
N
L
-
K
A
---
K
D
TNL
N
K
V
R
E
E
V
---------
G
M
V
F
Q
--
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
--
K
V
R
K
-
W
P
R
--
E
K
A
E
A
K
A
M
E
-
L
L
D
K
V
G
L
K
-
D
-
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
---
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
L
F
M
D
--
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
------------------------------------------------------------------------------------------------------------------
93
PsiBlast_CBE
54.79
33%
-117
- C1 -
4YMV
1
?
A:
[13-209]
---------------------------
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------
V
K
I
-
N
N
---
G
K
VN
I
N
K
V
R
Q
K
V
---------
G
M
V
F
Q
--
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
--
K
V
K
K
-
M
N
K
--
K
E
A
E
E
L
A
V
D
-
L
L
A
K
V
G
L
L
-
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
I
F
M
------------------------------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
53.72
33%
-121
- C1 -
4YMU
2
?
A:
[13-209]
---------------------------
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------
V
K
I
-
N
N
---
G
K
VN
I
N
K
V
R
Q
K
V
---------
G
M
V
F
Q
--
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
--
K
V
K
K
-
M
N
K
--
K
E
A
E
E
L
A
V
D
-
L
L
A
K
V
G
L
L
-
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
GM
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
I
F
M
------------------------------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
52.89
33%
-118
- C1 -
4YMV
1
?
J:
[13-209]
---------------------------
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------
V
K
I
-
N
N
---
G
K
VNINKVR
Q
K
V
---------
G
M
V
F
Q
--
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
--
K
V
K
K
-
M
N
K
--
K
E
A
E
E
L
A
V
D
-
L
L
A
K
V
G
L
L
-
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
I
F
M
------------------------------------------------------------------------------------------------------------------------------------------
94
PsiBlast_CBE
52.21
33%
-121
- C1 -
4YMU
2
?
J:
[13-209]
---------------------------
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------
V
K
I
-
N
N
---
G
K
VNINKVR
Q
K
V
---------
G
M
V
F
Q
--
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
--
K
V
K
K
-
M
N
K
--
K
E
A
E
E
L
A
V
D
-
L
L
A
K
V
G
L
L
-
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
----
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
EGM
T
M
V
V
V
T
H
E
M
G
F
A
------
R
E
V
G
D
R
V
I
F
M
------------------------------------------------------------------------------------------------------------------------------------------