@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA2530: (2016-02-08 )
MHQRQHFEALAEDLRRHLAEGEDFTLWYSAEDSEFIRFNRARVRQAGRVRQASALLRLIRDERQASLDLTLSGAPEEDRQRLAEGLRQLRQSLAWIPADPYLLLDTSAWQRENQDLGAAPDSGALLASLERRARDLDLVGIYAAGPLFRGFANSWGAFGWHAGSSFNFDWSLFHGNGQAVKADYAGQRWDDEAFARRFEQAREQLGHLGKPLRQLRPGDYRAYLAPAALEEVMQMLCWGGFSARALATGESPLQRLQNGDALLSPLLNLAERPATSPSPAFSAEGSPRAEVELVGNGRLSGRLVSSRSAREYGLVANGAGANEAPTALDMAGGSLEQARILEALDTGLYIGNLWYLNYSDMPAARLTGMTRFATFWVENGQIRAPVSTMRFDDSLYSFLGAHLEDLSHERELRLSSNTYGERQTDSMHLPGALTGRFTLTL
Atome Classification :
(20 SA)
--.........10.....--...20.........30.......-.40........50........60.-----.......70.-------.......-----80........90.....----...100.....---.-.-110.-----.--...--.---.--------------..120..-.....130..----..-.-----.-.140..-.....150.......160.......170-.....-..180.------------...---...--190-.......200...----....210.......----220....----...230......------.240---------------------------.........250..-..--...260.......270.--------...---...280.......--------------290.......-------------.300.......310.-----.--.....320.--..-----....330.....------..340.......350.......360......-.370.-----.-.....380.....-..390----.......400.......410.......420.......430.......440----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MH
Q
R
Q
H
F
E
A
L
A
E
D
L
R
R
--
H
LAE-GE
D
F
T
L
W
Y
SAEDS
E
F
I
R
F
-
N
R
A
R
V
R
Q
AG
R
V
R
Q
A
S
A
L
L
R
L
I
R
D
E
-----RQA
S
L
D
L
T
LS-------GA
P
E
E
D
R
-----
Q
R
L
A
E
G
L
R
Q
L
R
Q
SLAWI----PAD
P
Y
L
L
LDTS---A-W-Q--R-----E--NQD--L---G--------------AAPDS
G
A
-
L
L
A
S
L
E
R
R
AR----DL-
D
-----
L
-
V
G
I
YAA-
G
P
L
F
R
G
F
A
NSWGAFGWHAGSSF
N
F
D
W
S
L
-FHGNG-
Q
A
V
KAD------------YAG---QRW--
D
D
E
-
A
F
A
R
R
F
E
Q
A
R
E
Q
L
----
G
H
L
G
K
P
L
R
QLRPGD----Y
R
A
YL
A
P
----
A
A
L
E
E
V
M
Q
M
LCW------GG-----------------------------FS
A
R
ALAT
G
E
S
P
L
Q
-
R
L
--QNG
D
A
L
L
S
P
L
L
N
L
A
ERP--------ATS---PSPAFSAEGSP
R
A
--------------
E
-
V
E
L
V
GNGR-------------LS
G
R
L
VSSRSAREY
G
-----
L
--VANGAGANE--AP-----T
A
L
DMAGG
S
L
E
Q
------
A
R
I
L
E
A
L
DTG
L
Y
I
G
N
L
W
Y
LNYSDM
P
A
A
R
L
TG-M
T
R
F
A
-----
T
-
F
W
V
EN
G
Q
I
RAP
V
S
-TMRF
D
----
D
S
L
Y
S
F
L
G
A
H
L
E
D
L
S
H
E
R
E
L
RLSSNTYGERQTDSMHLPGALT
G
R
F
T
L
TL-----
23
HHSearch
98.01
18%
-41
- C7 -
3TV9
5
?
A:
[23-457]
---
N
A
R
K
I
L
E
E
A
V
S
T
A
L
E
L
-
A
S
G
K
-
S
D
G
A
E
V
A
V
S
K
T
T
G
I
S
V
S
T
-
R
Y
G
E
V
E
N
V
E
F
N
S
D
G
A
L
G
I
T
V
Y
H
Q
N
-----
R
K
G
S
A
S
S
T
------------
D
L
S
P
-----
Q
A
I
A
R
T
V
Q
A
A
L
D
I
A
R
Y
T
----
S
P
D
P
C
A
G
V
A
D
K
---
E
-
L
L
A
F
D
A
-----
P
N
L
D
L
F
--
H
P
A
E
V
--------------
S
P
D
E
A
I
E
-
L
A
A
R
A
E
Q
A
A
L
Q
ADK
R
I
T
N
-----
T
E
G
G
S
F
N
S
-
H
Y
G
V
K
V
F
G
N
S
H
G
M
L
Q
G
Y
C
S
T
R
H
S
L
F
S
C
V
-
I
A
E
E
---
D
M
E
R
D
------------
Y
A
Y
T
I
G
R
A
M
--
S
D
L
Q
T
P
E
W
V
G
A
D
C
A
R
R
T
----
L
S
-
R
L
S
P
R
K
L
S
T
M
K
----
A
P
V
I
F
A
N
----
E
V
A
T
G
L
F
G
H
L
V
-------
G
A
-----------------------------
I
A
G
G
S
V
Y
R
K
S
T
F
L
L
-
D
---
S
L
G
K
Q
I
L
P
D
W
L
T
I
E
E
H
P
--------
H
L
L
KGL
A
S
T
P
F
D
S
E
G
V
R
T
E
--------------
R
-
R
D
I
I
K
D
G
I
-------------
L
T
Q
W
L
L
T
S
Y
S
A
R
K
L
G
-----
L
--
K
S
T
G
H
A
--
G
--
G
I
-----
H
N
W
R
I
A
G
Q
G
L
S
F
------
E
Q
M
L
K
E
M
G
T
G
L
V
V
T
E
L
M
G
Q
G
-
V
S
A
----
I
T
G
-
D
Y
S
R
G
A
A
---
G
-
F
W
V
E
N
G
E
I
Q
Y
P
V
S
-
E
I
T
I
A
----
G
N
L
K
D
M
W
R
-
N
I
V
T
V
G
N
D
I
E
T
R
S
-
N
I
Q
C
-----
G
S
V
L
L
P
E
M
K
I
------------
24
HHSearch
94.68
16%
-56
- C7 -
1VPB
2
?
A:
[15-448]
-----
T
D
E
N
K
K
L
A
Q
W
A
M
D
Y
A
L
K
N
G
-
C
Q
A
A
K
V
L
L
Y
S
S
S
N
T
S
F
E
L
-
R
D
--
M
D
R
L
Q
Q
A
S
E
G
G
L
S
L
S
L
Y
V
D
G
-----
R
Y
G
S
I
S
T
N
------------
R
L
N
R
-----
K
E
L
E
T
F
I
K
N
G
I
D
S
T
R
Y
L
----
A
K
D
E
A
R
V
L
A
D
P
---
S
R
Y
-
Y
--
K
GGKPD
L
--
K
L
Y
--
D
---
A
KFASL---------
N
P
D
D
K
I
E
-
M
A
K
A
V
A
E
E
A
L
GKDE
R
I
-
I
S
----
V
-
G
S
S
Y
G
D
-
G
E
D
F
A
Y
R
L
I
S
N
G
F
E
G
E
T
K
S
T
W
Y
S
L
S
A
D
I
-
T
I
R
G
E
G
E
A
R
P
S
A
------------
Y
W
Y
E
S
S
L
Y
M
--
N
D
L
-
I
K
K
G
I
G
Q
K
A
L
E
R
V
----
L
R
-
K
L
G
Q
K
K
V
Q
S
G
K
----
Y
T
M
V
V
D
P
----
M
N
S
S
R
L
L
S
P
M
I
-------
S
A
-----------------------------
L
N
G
S
A
L
Q
Q
K
N
S
F
L
L
--
N
--
K
L
N
E
K
I
A
S
D
R
L
T
L
T
D
E
P
--------
H
L
V
KAS
G
A
R
Y
F
D
N
E
G
I
A
T
E
--------------
R
-
R
S
I
F
D
K
G
V
-------------
L
N
T
Y
F
I
D
T
Y
N
A
K
K
M
G
-----
V
--
D
P
T
I
S
G
------
S
-----
S
I
L
V
M
E
T
G
D
K
N
L
------
D
G
L
I
A
G
V
E
K
G
I
L
V
T
G
F
N
G
G
N
-
N
N
S
----
S
T
G
-
D
F
S
Y
G
I
E
---
G
-
F
L
I
E
N
G
K
L
T
Q
P
V
S
-
E
M
N
V
T
----
G
N
L
I
T
L
W
N
-
S
L
V
A
T
G
N
D
P
R
L
------
N
-----
S
S
W
R
I
P
S
L
V
F
E
G
V
D
F
-------
22
HHSearch
92.82
17%
-45
- C7 -
3QTD
2
?
A:
[11-448]
---
S
V
L
P
D
L
R
E
Q
V
E
Q
I
I
A
E
A
R
R
Q
G
-
A
S
A
C
E
V
A
V
S
L
E
Q
G
L
S
T
S
V
-
R
Q
G
E
V
E
T
V
E
F
N
R
D
Q
G
F
G
I
T
L
Y
A
G
Q
-----
R
K
G
S
A
S
T
S
------------
A
T
G
E
-----
A
A
I
R
E
T
V
A
A
A
L
A
I
A
R
H
T
----
S
E
D
E
C
A
G
L
A
D
A
---
A
L
M
-
A
RE
L
PE---
L
--
D
L
Y
--
H
---
P
W
SL-----------
S
P
E
Q
A
V
E
-
R
A
L
A
C
E
A
A
A
F
A
A
DK
R
V
-
T
K----
A
D
G
T
T
L
N
T
-
H
Q
G
C
R
V
Y
G
N
S
H
G
F
I
G
G
Y
A
S
T
R
H
S
L
S
C
V
M
-
I
A
E
G
E
-
G
Q
M
Q
R
D
------------
Y
W
Y
D
V
N
R
R
G
--
E
A
L
A
S
A
E
S
I
G
R
R
A
A
E
R
A
----
A
S
-
R
L
G
A
R
P
V
Q
T
A
E
----
V
P
V
L
F
A
P
----
E
I
A
V
G
L
F
G
H
F
-
L
------
G
A
-----------------------------
I
S
G
G
S
L
Y
R
K
S
S
F
L
E
-
G
---
A
L
G
Q
R
L
F
P
E
W
L
S
I
D
E
R
P
--------
H
L
V
GAL
G
S
A
S
F
D
S
D
G
L
A
T
Y
--------------
A
-
K
P
F
V
E
N
G
E
-------------
L
V
S
Y
V
L
G
T
Y
S
G
R
K
L
G
-----
L
--
P
S
T
A
N
A
--
G
--
G
V
-----
H
N
L
F
V
S
H
G
D
E
D
Q
------
A
A
L
I
R
R
M
E
R
G
L
L
V
T
E
L
M
G
Q
-
G
V
N
L
----
V
T
G
-
D
Y
S
R
G
A
A
---
G
-
Y
W
V
E
N
G
E
I
Q
F
P
V
Q
-
E
V
T
I
A
----
A
N
L
R
D
L
F
R
-
R
I
V
A
V
G
K
D
I
E
R
------
R
G
N
L
H
T
G
S
V
L
V
E
S
M
M
V
A
G
----------
32
Fugue
92.61
14%
-49
* C7 *
1VL4
-
?
A:
[2-433]
-------
T
F
E
E
F
K
D
R
L
F
A
--
L
A
K
K
N
G
V
E
V
Q
I
S
F
L
E
T
R
E
F
S
L
R
L
-
A
N
G
D
L
D
Q
Y
T
D
A
G
K
F
N
V
E
I
K
V
L
K
D
G
-----
K
T
G
T
F
R
T
Q
-----------
V
L
E
N
P
-----
E
K
C
F
E
E
A
L
S
N
L
Q
V
K
K
E
Y
----
F
F
E
G
G
K
E
Y
R
E
M
---
E
-
T
-
Y
--
V
-----
G
--
R
F
E
--
K
---
L
--------------
S
V
K
E
K
M
D
-
M
A
K
K
A
H
E
S
A
A
----
K
D
-
E
RVVMV
P
-
T
V
M
Y
K
D
-
M
V
I
K
K
I
I
T
N
T
L
G
L
D
V
E
S
Q
M
D
G
G
F
L
F
A
M
A
-
I
A
R
D
A
N
P
R
S
G
S
W
------------
Y
E
L
---
A
R
T
--
P
E
D
-
L
N
P
E
E
I
G
K
R
A
A
E
E
----
A
I
S
L
I
G
S
K
T
I
P
S
G
K
----
Y
P
V
L
M
R
N
----
T
A
L
L
D
L
M
E
M
F
-
I
------
P
M
-----------------------------
I
S
A
E
N
V
Q
K
N
L
S
P
L
K
-
G
---
K
L
G
E
Q
V
G
N
P
A
V
S
I
K
D
L
P
--------
Y
H
P
KGL
S
S
T
P
F
D
D
E
G
V
P
T
T
--------------
E
-
K
F
V
L
E
N
G
V
-------------
L
K
T
F
L
H
N
L
K
T
A
R
K
E
G
-----
V
--
E
P
T
G
N
G
F
V
G
GI
R
P
-----
V
N
L
M
L
M
P
G
E
K
S
F
------
E
E
L
L
K
E
M
D
R
G
V
V
I
T
E
V
E
G
-
M
H
A
G
A
N
S
I
S
G
E
F
-
S
L
F
A
K
-----
G
-
Y
W
V
E
N
G
E
I
A
H
G
V
E
-
D
I
T
I
S
----
G
N
F
L
D
L
L
R
-
K
I
V
L
V
G
N
D
V
K
V
S
-----------
Q
H
T
I
A
P
S
V
L
V
E
V
L
D
V
A
------
1
PsiBlast_PDB
72.85
27%
-55
- C7 -
1VL4
-
?
A:
[206-387]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
E
A
I
----
S
L
I
G
S
--
K
T
I
P
S
G
K
----
Y
P
V
L
M
R
N
----
T
A
L
L
D
L
M
E
M
F
I
P
------
M
------------------------------
I
S
A
E
N
V
Q
K
N
L
S
P
L
K
G
K
L
GE
Q
V
G
N
P
A
V
S
-
I
K
D
L
P
Y
H
P
--------
K
G
L
---
S
S
T
P
F
D
D
E
G
V
P
T
T
--------------
E
-
K
F
V
L
E
N
G
V
-------------
L
K
T
F
L
H
N
L
K
T
A
R
K
E
G
-----
V
EP
T
G
N
G
F
V
G
G
I
--
R
P
-----
V
N
L
M
L
M
P
G
E
K
S
F
------
E
E
L
L
K
E
M
D
R
G
V
V
I
T
E
V
E
G
M
H
A
G
---
A
N
S
I
S
G
E
F
S
L
F
A
-----
K
G
Y
W
V
E
N
G
E
I
---------------------------------------------------------------------
34
Fugue
71.79
22%
-30
- C4 -
4QNU
3
CMOB_ECOK1
A:
[1-323]
--
M
I
D
F
G
N
F
Y
S
L
I
A
--
K
N
--
H
L
-------
S
H
W
L
E
T
L
P
A
Q
I
A
N
W
-
Q
R
E
Q
--
Q
H
G
L
F
K
Q
W
S
N
A
V
E
F
L
P
E
I
-----
K
P
Y
R
L
D
L
L
H
S
V
T
A
E
S
EE
P
L
S
A
G
Q
I
-----
K
R
I
E
T
L
M
R
N
L
M
P
---
W
-----
R
K
G
P
F
S
L
Y
G
V
N
IDT
E
-
W
-
R
---------------------------------------
S
D
W
-
K
W
D
R
V
L
P
H
L
S
----
D
L
-
T
-----
G
-
R
T
I
L
D
V
-
G
----------------
C
G
S
G
Y
H
M
W
R
M
I
-
G
A
G
A
H
-
L
A
V
G
I
D
-----------------------
P
T
Q
-
L
F
L
C
Q
F
E
A
V
R
K
L
L
----
G
-----------
N
D
----
Q
R
A
H
L
L
P
----
L
G
I
E
Q
--------------------------------------------------------
L
P
-
A
L
--
K
A
F
D
T
V
F
S
M
--------------------------------------------------------------------------
G
V
L
Y
H
R
R
S
P
L
E
H
L
-----
W
--
Q
L
K
D
Q
L
V
N
E
--
G
E
-----
L
V
L
E
T
L
V
I
D
G
D
E
------
N
T
V
L
V
P
G
D
R
Y
A
Q
M
R
N
V
Y
F
I
P
-
S
A
L
A
L
K
N
W
L
K
-
K
C
G
F
V
-----
D
-
I
R
I
A
D
V
S
V
T
T
T
E
E
-
Q
R
R
T
E
WMVT
E
S
L
A
D
F
L
D
P
H
D
P
G
K
T
V
E
G
--------------
Y
P
A
P
K
R
A
V
L
I
A
R
K
P
--------
37
Fugue
66.53
13%
-45
* C4 *
2BVL
8
TOXB_PEPDI
A:
[1-543]
MS
L
V
N
R
K
Q
L
E
K
M
A
N
--
V
R
--
F
R
T
Q
-
E
D
E
Y
V
A
I
L
D
A
L
E
E
Y
H
N
M
S
-
E
N
T
V
V
E
K
Y
L
K
L
K
D
I
N
S
L
T
D
I
C
I
D
T
Y
KKSG
R
N
K
A
L
K
K
F
K
E
-------
Y
L
V
T
E
V
L
-----
E
L
K
N
N
N
L
T
P
V
E
K
N
L
H
F
V
W
I
GG
Q
I
N
D
T
A
I
N
Y
I
N
---
Q
-
W
-
K
--
D
-----
V
--
N
S
D
Y
N
V
---
N
--------------
V
F
Y
D
S
N
A
F
L
I
N
T
L
K
K
T
V
V
----
E
S
-
A
-----
I
-
N
D
T
L
E
S
F
R
E
N
L
N
D
P
R
F
D
Y
N
K
F
F
R
K
R
M
E
I
I
Y
D
K
Q
K
N
-
F
I
N
Y
Y
-
K
A
Q
R
E
E
NPELI
I
D
D
I
V
K
T
Y
L
S
---
N
E
Y
SK
E
I
D
-
E
L
N
T
Y
I
E
E
S
L
N
K
I
T
Q
N
S
G
N
D
V
R
N
F
G
E
F
K
N
G
E
S
F
N
L
Y
E
Q
E
L
V
E
RWN
L
A
A
A
S
D
I
L
R
I
S
A
L
------
K
E
IG
G
M
Y
L
D
VDMLPGIQPDLFESIEKPSSVT
V
D
F
W
E
M
T
K
L
E
A
I
M
K
-
Y
K
--
E
Y
I
P
E
Y
T
S
E
H
F
D
M
L
D
E
E
--------
V
Q
S
---
S
F
E
S
V
L
A
S
K
S
D
K
S
EIFSSL
G
D
M
E
A
S
PL
E
-
V
K
I
A
F
N
S
K
GIINQ
G
L
I
S
V
K
DS
Y
C
S
N
L
I
V
K
Q
I
E
N
R
Y
K
-----
I
--
L
N
N
S
L
N
P
A
I
--
S
E
DND
F
N
T
T
T
N
T
F
I
D
S
I
M
A
E
ANADN
G
R
F
M
M
E
L
G
K
Y
L
R
V
G
--
F
F
P
D
V
K
--
T
T
I
N
L
S
G
-
P
E
A
Y
A
-----
A
-
A
Y
Q
D
L
L
M
F
K
E
G
S
M
-
N
I
H
L
I
----
E
A
D
L
R
N
F
E
I
S
K
T
N
I
S
Q
S
T
E
Q
E
M
A
S
L
W
S
F
D
D
A
R
A
K
A
Q
F
E
E
Y
K
R
N
Y
F
E
G
A
L
-----
40
Fugue
64.82
15%
-13
- C4 -
3FHC
-
NU214_HUMAN
A:
[9-405]
--
I
P
E
R
E
M
K
D
F
Q
F
R
A
L
K
K
--
V
R
I
F
-
D
S
P
E
E
L
--
P
K
E
R
S
S
L
L
A
V
S
N
K
Y
G
L
V
F
A
G
----
G
A
S
G
L
Q
I
F
P
----------
T
K
N
L
L
I
Q
-------
N
K
P
G
D
D
P
-----
N
K
I
V
D
K
V
Q
G
L
L
V
P
M
K
F
--------
P
I
H
H
L
A
L
S
---
C
-
D
-
N
--
L
-----
T
--
L
S
A
--
C
---
M
--------------
M
S
S
E
Y
G
S
-
I
I
A
F
F
D
-----------------------------
V
R
T
F
S
N
E
--------
A
Q
K
R
P
F
A
Y
H
K
-
L
L
K
D
A
-
G
G
M
V
I
D
------------
M
K
W
---
N
P
T
--
V
P
S
-
M
V
A
V
C
L
A
D
G
S
I
A
V
----
L
Q
V
T
E
T
V
K
V
C
A
T
L
-----------
P
----
S
T
V
A
--
V
T
S
V
C
W
------
S
P
------------------------------
K
G
K
Q
L
A
V
G
K
---------
Q
N
G
T
V
V
Q
Y
-
L
P
T
L
Q
E
K
K
--------
V
I
P
---
C
P
P
F
Y
E
S
D
H
P
V
R
V
--------------
L
D
V
L
W
I
G
T
Y
V
-------------
F
A
I
V
Y
A
A
A
D
G
T
L
E
T
S
P
D
V
V
M
A
--
L
L
P
K
K
E
E
K
H
--
P
E
-----
I
F
V
N
F
M
E
P
C
Y
G
S
------
C
T
E
R
Q
H
H
Y
Y
L
S
Y
I
E
E
W
D
L
V
L
A
A
S
A
A
S
T
E
V
S
I
-
L
A
R
Q
S
DQI
N
W
E
-
S
W
L
L
E
D
S
S
R
A
E
L
P
-
V
--
T
D
----
K
S
D
D
S
L
P
M
G
V
V
V
D
Y
T
N
A
P
V
L
M
L
L
S
-------
T
D
G
V
L
C
P
F
Y
M
I
N
-----------
2
PsiBlast_PDB
59.62
30%
-18
- C7 -
3TV9
2
?
A:
[291-425]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
Q
I
L
P
D
W
L
T
I
E
E
H
P
HLLKGL--
A
S
T
---
P
---
F
D
S
E
G
V
R
T
E
--------------
R
-
R
D
I
I
K
D
G
I
-------------
L
T
Q
W
L
L
T
S
Y
S
A
R
K
L
G
-----
L
--
K
S
T
G
H
A
G
G
I
--
H
N
-----
W
R
I
A
G
Q
G
L
S
F
E
Q
------
M
--
L
K
E
M
G
T
G
L
V
V
T
E
L
M
G
Q
G
V
S
A
I
T
G
D
Y
S
R
G
-
A
---
A
-----
G
-
F
W
V
E
N
G
E
I
Q
Y
P
V
S
-
E
I
T
I
A
----
G
N
L
---------------------------------------------------
36
Fugue
58.13
9%
-19
- C6 -
3R6N
2
DESP_HUMAN
A:
[1-450]
--
S
G
W
D
E
F
T
K
H
V
T
S
E
C
L
G
--
W
M
R
Q
-
Q
R
A
E
-
M
D
M
V
A
W
G
V
D
L
A
S
V
-
E
Q
H
I
N
S
H
R
G
I
H
N
S
I
G
D
Y
R
W
Q
L
D
K
I
-----
K
A
D
L
R
E
K
S
A
I
-------
Y
Q
L
E
E
E
Y
-----
E
N
L
L
K
A
S
F
E
R
M
D
H
L
R
Q
L
----
Q
N
I
I
Q
A
T
S
R
E
I
---
M
-
W
-
I
--
N
-----
D
--
C
E
E
--
E
---
E
L
L
YDWSDKNTN
I
A
Q
K
Q
E
A
F
S
I
-
R
M
S
Q
L
E
V
K
E
K
----
E
L
-
N
-----
K
-
L
K
Q
E
S
D
-
Q
L
V
L
N
Q
--
H
P
A
S
D
K
I
E
A
Y
M
D
T
L
Q
T
Q
W
S
W
-
I
L
-
Q
I
-
T
K
C
I
D
V
------------
H
L
K
---
E
N
A
--
A
Y
F
-
Q
F
F
E
E
A
Q
S
T
E
A
Y
L
----
K
G
L
Q
D
S
I
R
K
K
Y
P
C
D
---------
K
N
----
M
P
L
Q
H
L
L
E
Q
I
K
E
------
L
E
-----------------------------
K
E
R
E
K
I
L
E
Y
K
R
Q
V
Q
-
N
L
--
V
N
K
S
K
K
I
V
Q
L
K
P
R
N
P
D
Y
--------
R
S
N
---
K
P
I
I
L
R
A
L
C
D
Y
K
Q
--------------
D
-
Q
K
I
V
H
K
G
D
--------------
E
C
I
L
K
D
N
N
E
R
S
K
W
Y
-----
V
--
T
G
P
G
G
V
D
M
L
--
V
P
-----
S
V
G
L
I
I
P
P
P
N
P
L
------
A
V
D
L
S
C
K
I
E
Q
Y
Y
E
A
I
L
A
L
W
N
Q
L
Y
I
N
M
K
S
L
V
S
-
W
H
Y
C
M
-----
I
-
D
I
E
K
I
R
A
M
T
I
A
K
L
-
K
T
M
R
Q
----
E
D
Y
M
K
T
I
A
D
L
E
L
H
Y
Q
E
F
I
R
N
S
Q
G
S
E
M
F
G
D
D
D
K
R
K
I
Q
S
Q
F
T
D
A
Q
K
H
Y
Q
T
L
V
I
Q
LP
41
Fugue
57.55
11%
-30
- C2 -
3LZC
-
DPH2_PYRHO
A:
[1-342]
------------------------------
M
L
H
E
I
P
---------------------
K
S
E
I
L
K
E
L
K
R
I
-----
G
A
K
R
V
L
I
Q
S
P
-------
E
G
L
R
R
E
A
-----
E
E
L
A
G
F
L
E
E
N
N
I
E
V
F
L
H
----
G
E
I
N
Y
-----------------------------------------------------
G
A
C
-
D
P
A
D
R
E
A
K
L
V
----
G
C
-
D
-----
A
-
L
I
H
L
G
H
-
S
Y
M
K
L
--
P
L
E
V
P
T
I
F
V
P
A
F
A
R
V
S
V
V
E
A
L
-
K
E
N
I
G
-
E
I
K
K
L
G
------------
R
K
I
---
I
V
T
--
T
T
A
-
Q
H
I
H
Q
L
K
E
A
K
E
F
L
----
E
S
E
G
F
E
V
S
I
G
R
G
D
S
---------
R
I
----
S
W
P
G
Q
V
L
------------
G
-----------------------------
C
N
Y
S
V
A
K
V
R
G
E
G
I
L
-
F
I
--
G
S
G
I
F
H
P
L
G
L
A
V
A
T
R
K
K
--------
V
L
A
---
I
D
P
Y
T
K
A
F
S
W
I
D
P
--------------
E
-
R
F
I
R
K
R
W
A
-------------
Q
I
A
K
---
A
M
D
A
K
K
F
G
-----
V
--
I
V
S
I
K
K
G
Q
L
--
R
L
-----
A
E
A
K
R
I
V
K
L
L
K
K
------
H
G
R
-----------
E
A
R
L
I
V
M
N
D
V
N
Y
H
K
L
E
G
-
F
P
F
-------
E
-
A
Y
V
V
V
A
C
P
R
V
P
L
D
D
Y
G
A
W
R
----
K
P
V
L
T
P
K
E
V
E
I
L
-
L
G
L
R
E
E
Y
E
F
D
E
I
L
G
G
P
R
E
S
D
E
P
F
G
I
S
I
H
S
T
R
----------
3
PsiBlast_PDB
54.01
26%
-34
- C7 -
3QTD
-
?
A:
[280-414]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
R
L
F
P
E
W
L
S
I
D
E
R
P
HLV-----
G
A
L
---
G
S
A
S
F
D
S
D
G
L
A
T
Y
--------------
A
-
K
P
F
V
E
N
G
E
-------------
L
V
S
Y
V
L
G
T
Y
S
G
R
K
L
G
-----
L
P
S
T
A
N
A
G
G
V
H
N
-----------
L
F
V
S
H
G
D
E
D
Q
------
A
A
L
I
R
R
M
E
R
G
L
L
V
T
E
L
M
G
Q
G
V
N
L
V
T
G
D
Y
S
R
G
-
A
---
A
-----
G
-
Y
W
V
E
N
G
E
I
Q
F
P
V
Q
-
E
V
T
I
A
----
A
N
L
---------------------------------------------------
14
PsiBlast_PDB
47.68
28%
7
- C5 -
1M41
-
SSUD_ECOLI
A:
[1-138]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
N
M
F
W
F
L
P
T
H
G
D
G
-
H
Y
L
G
T
E
-------------
E
G
---
S
R
P
--
V
D
H
-
G
Y
L
Q
Q
I
A
Q
A
A
D
R
L
----
G
Y
T
G
V
L
I
P
T
G
R
S
C
E
-----
D
A
W
L
V
A
----
A
S
M
I
P
V
T
Q
R
L
K
F
L
V
A
L
R
P
S
V
-----------------------------
T
S
P
T
V
A
A
R
Q
A
A
T
L
D
-
R
L
--
S
N
G
R
A
L
F
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
47.17
28%
15
- C5 -
1NQK
-
SSUD_ECOLI
A:
[2-123]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
N
M
F
W
F
L
P
T
H
G
D
G
-
H
Y
L
G
T
E
-------------
E
G
---
S
R
P
--
V
D
H
-
G
Y
L
Q
Q
I
A
Q
A
A
D
R
L
----
G
Y
T
G
V
L
I
P
T
G
R
S
C
E
-----
D
A
W
L
V
A
----
A
S
M
I
P
V
T
Q
R
L
K
F
L
V
A
L
R
P
S
V
-----------------------------
T
S
P
T
V
A
A
R
Q
A
A
T
L
D
-
R
L
--
S
N
G
R
A
L
F
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
46.98
29%
37
- C5 -
3H2Z
2
MTLD_SHIFL
A:
[294-377]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
Q
P
L
R
-
K
L
--
S
A
G
D
R
L
I
K
P
L
L
G
T
L
E
Y
S
LPH
K
N
L
I
Q
G
I
A
---
G
A
M
H
F
R
S
E
D
D
P
Q
A
--------------
Q
--
E
L
A
--
A
L
-------------
I
A
D
K
G
P
Q
A
A
L
A
Q
I
S
G
-----
L
--
D
A
N
S
E
V
V
S
E
--
A
V
-----
T
A
-----------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
46.70
26%
-6
- C5 -
3IEH
4
?
A:
[24-112]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
-
N
F
Y
L
L
L
E
Q
E
M
T
R
L
----
G
M
V
E
K
N
L
G
E
V
G
K
Y
K
----
V
S
L
Y
Q
S
P
----
A
A
K
S
G
L
P
S
L
L
I
S
------
A
G
-----------------------------
F
H
G
E
E
S
A
G
P
W
G
L
L
H
-
F
L
--
S
E
A
S
A
D
L
F
E
R
V
N
L
S
L
L
P
--------
L
V
N
---
P
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
44.29
37%
74
- C5 -
1VA0
3
?
B:
[164-217]
-----------------------------------------------------
R
V
W
I
A
K
E
L
L
R
L
G
R
D
P
-----
R
E
P
T
L
F
V
E
R
A
-------
S
T
P
K
E
R
R
V
H
A
R
L
E
E
V
A
E
G
K
V
E
V
R
P
P
A
L
W
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
43.33
37%
79
- C5 -
1V9A
2
?
B:
[164-217]
-----------------------------------------------------
R
V
W
I
A
K
E
L
L
R
L
G
R
D
P
-----
R
E
P
T
L
F
V
E
R
A
-------
S
T
P
K
E
R
R
V
H
A
R
L
E
E
V
A
E
G
K
V
E
V
R
P
P
A
L
W
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
42.54
37%
64
- C5 -
1V9A
2
?
A:
[164-217]
-----------------------------------------------------
R
V
W
I
A
K
E
L
L
R
L
G
R
D
P
-----
R
E
P
T
L
F
V
E
R
A
-------
S
T
P
K
E
R
R
V
H
A
R
L
E
E
V
A
E
G
K
V
E
V
R
P
P
A
L
W
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
42.12
38%
98
- C6 -
1Z56
-
LIF1_YEAST
A:
[183-232]
--------------------------------------------
N
R
N
R
V
E
Q
L
A
R
E
R
E
L
L
D
K
L
L
E
T
R
D
E
-----
R
T
R
A
M
M
V
T
L
L
-------
N
E
K
K
K
K
I
-----
R
E
L
H
E
I
L
R
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------