@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA2572: (2016-02-09 )
MNDSAPPSNETEIRFSVLLVDDEPLILSSLRRLLRNQPYDLLLAESGEQALQLLESRPVDLVVSDARMPNMDGAALLAEIHRRSPETIRILLTGHADLPTIAKAINEGRIHHYLSKPWNDDELLLTLRQSLEYLHSERERRRLERLTQEQNDRLQQLNATLEKRVQARTAELQQTADMLDLAYEELKRSYVVGTEVFSLLVNQRLPKDKQTNQQIIELVRACCASGLVDESDGRDLAMAAALYNIGKLSWNDTLLSSPSDLLYHHDRDRFRGYPELSESLLMSLEPMQDAARLIRHHQEHWDGSGYPDHLKGEAIPLGSRLLKLAVDFVELQRGLILERRMNRDEALMYIRKYAGRLYDPELIEPFIQVCATTLADVTLADPQVRAHGTRDLVPGMVLARNLTANNGMLLLNAGKVLNLALIEKLIAFEAIEGARYTLFVRLPESTT
Atome Classification :
(20 SA)
.........10........20........30........40..-----......50......--..60........70........80........--90........100....-...110.......120.......130.......140.--......150.......160.......170.......180.......190...-....200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......-360.......370..-.....380.......390.......400.......410.......420.......430.......440.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNDSAPPSNE
T
E
I
R
F
S
V
L
L
VDDE
P
L
I
L
S
S
L
R
R
L
L
RNQP
Y
D
L
L
L
-----AES
G
E
Q
A
L
Q
L
L
E
SR--P
V
D
L
V
VSDARMPNM
D
G
A
A
L
L
A
E
I
HRRSP
E
T
I
R
--
I
L
L
TGHAD
L
P
T
I
A
K
A
I
N-EG
R
I
H
H
Y
L
SKPWN
D
D
E
L
L
L
T
L
R
Q
S
L
E
Y
L
H
S
E
R
E
R
R
R
L
--
E
R
L
T
Q
E
Q
N
D
R
L
Q
Q
L
N
A
T
L
E
K
R
V
Q
A
R
T
A
E
L
Q
Q
T
A
D
M
L
D
L
A
Y
E
E
L
K
R
S
Y
V
V
G
T
E
-
V
F
S
L
L
V
N
QRLPKDKQT
N
Q
Q
I
I
E
L
V
R
A
C
C
ASGLVDESDG
R
D
L
A
M
A
A
A
L
Y
N
IGKLSWNDTLLSS
P
S
D
L
L
YHH
D
R
D
R
FRGY
P
E
L
S
E
S
L
L
M
S
LE
P
M
Q
D
A
A
R
L
I
R
H
H
Q
E
HWDGSGYPDHLKGEAI
P
L
G
S
R
L
L
K
L
A
V
D
F
V
E
L
Q
R
G
L
I
L
E
R
RM
N
R
D
E
A
L
M
Y
I
R
K
Y
AGRLY
D
-
P
E
L
I
E
P
F
I
Q
V
C
A
T
T
L
-A
D
V
TLAD
P
Q
VRAHGTRDLV
P
G
M
V
L
A
RNLTANN
G
M
L
L
LNAGK
V
L
N
L
A
L
I
E
K
L
I
A
F
E
AIEGA
R
Y
T
L
F
V
RLPESTT
1
PsiBlast_PDB
84.26
61%
-100
- C6 -
3HV2
1
?
A:
[14-141]
-------------
R
P
E
I
L
L
V
D
S
Q
E
V
I
L
Q
R
L
Q
Q
L
L
S
P
L
P
Y
T
L
H
F
-----
A
R
D
A
T
Q
A
L
Q
L
L
A
S
R
--
E
V
D
L
V
I
S
A
A
H
L
P
Q
M
D
G
P
T
L
L
A
R
I
H
Q
Q
Y
P
S
T
T
R
--
I
L
L
T
G
D
P
D
L
K
L
I
A
K
A
I
N
-
E
G
E
I
Y
R
Y
L
S
K
P
W
D
D
Q
E
L
L
L
A
L
R
Q
A
L
E
H
Q
H
S
E
R
E
R
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
82.39
61%
-102
- C6 -
3HV2
2
?
B:
[14-137]
-------------
R
P
E
I
L
L
V
D
S
Q
E
V
I
L
Q
R
L
Q
Q
L
L
S
P
L
P
Y
T
L
H
F
-----
A
R
D
A
T
Q
A
L
Q
L
L
A
S
R
--
E
V
D
L
V
I
S
A
A
H
L
P
Q
M
D
G
P
T
L
L
A
R
I
H
Q
Q
Y
P
S
T
T
R
--
I
L
L
T
G
D
P
D
L
K
L
I
A
K
A
I
N
-
E
G
E
I
Y
R
Y
L
S
K
P
W
D
D
Q
E
L
L
L
A
L
R
Q
A
L
E
H
Q
H
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120
HHSearch
81.85
58%
-99
- C6 -
3HV2
1
?
A:
[9-133]
--------
A
T
V
T
R
R
P
E
I
L
L
V
D
S
Q
E
V
I
L
Q
R
L
Q
Q
L
L
S
P
L
P
Y
T
L
H
F
-----
A
R
D
A
T
Q
A
L
Q
L
L
A
S
R
--
E
V
D
L
V
I
S
A
A
H
L
P
Q
M
D
G
P
T
L
L
A
R
I
H
Q
Q
Y
P
S
T
T
R
--
I
L
L
T
G
D
P
D
L
K
L
I
A
K
A
I
N
-
E
G
E
I
Y
R
Y
L
S
K
P
W
D
D
Q
E
L
L
L
A
L
R
Q
A
L
E
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
127
Fugue
78.68
18%
-62
* C5 *
1NY5
8
?
A:
[1-384]
--------------
M
N
V
L
V
I
E
D
D
K
V
F
R
G
L
L
E
E
Y
L
S
M
K
G
I
K
V
E
S
-----
A
E
R
G
K
E
A
Y
K
L
L
S
E
K
--
H
F
N
V
V
L
L
D
L
L
L
P
D
V
N
G
L
E
I
L
K
W
I
K
E
R
S
P
E
T
E
V
--
I
V
I
T
G
H
G
T
I
K
T
A
V
E
A
M
K
-
M
G
-
A
Y
D
F
L
T
K
P
C
M
L
E
E
I
E
L
T
I
N
K
A
I
E
H
R
K
L
R
K
E
N
E
L
L
--
R
R
E
K
D
L
K
E
E
E
Y
V
-----------
F
E
S
P
K
M
K
E
I
L
E
K
I
K
K
I
S
C
A
E
C
P
V
L
I
T
G
E
S
G
V
G
K
E
V
V
A
R
L
I
H
K
L
S
D
R
S
K
E
P
F
V
A
L
N
V
---------
A
S
I
P
R
D
I
F
E
A
E
L
F
G
Y
E
K
G
A
F
T
G
A
V
S
S
K
E
G
F
F
E
L
A
D
G
-----
G
T
L
F
L
D
E
I
G
E
L
S
L
E
A
Q
A
K
L
L
R
V
I
E
S
G
K
F
Y
R
L
G
G
R
K
E
I
E
V
N
V
R
I
L
A
A
T
N
R
N
I
K
E
L
V
K
E
G
K
F
R
E
D
L
Y
Y
R
L
----
G
V
I
E
I
E
I
P
P
L
R
E
R
K
E
D
I
I
P
L
A
N
H
F
L
K
K
F
S
R
K
Y
A
K
E
V
E
G
F
T
K
S
A
Q
E
L
L
L
S
Y
P
W
Y
G
----------------------
N
V
R
E
L
K
N
V
I
E
R
A
V
L
F
S
E
G
K
F
I
D
R
G
E
L
S
C
L
V
2
PsiBlast_PDB
73.15
38%
-103
- C6 -
2JK1
1
HUPR_RHOCA
A:
[3-129]
---------------
A
I
L
L
V
D
D
E
P
H
S
L
A
A
M
K
L
A
L
E
D
D
-
F
D
V
L
T
-----
A
Q
G
A
E
A
A
I
A
I
L
E
E
E
--
W
V
Q
V
I
I
C
D
Q
R
M
P
G
R
T
G
V
D
F
L
T
E
V
R
E
R
W
P
E
T
V
R
--
I
I
I
T
G
Y
T
D
S
A
S
M
M
A
A
I
N
-
D
A
G
I
H
Q
F
L
T
K
P
W
H
P
E
Q
L
L
S
S
A
R
N
A
A
R
M
F
T
L
A
R
E
N
E
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
119
HHSearch
71.71
34%
-111
* C6 *
2RJN
-
?
A:
[4-125]
----------
N
Y
K
N
Y
T
V
M
L
V
D
D
E
Q
P
I
L
N
S
L
K
R
L
I
K
R
L
G
C
N
I
I
T
-----
F
T
S
P
L
D
A
L
E
A
L
K
G
T
--
S
V
Q
L
V
I
S
D
M
R
M
P
E
M
G
G
E
V
F
L
E
Q
V
A
K
S
Y
P
D
I
E
R
--
V
V
I
S
G
Y
A
D
A
Q
A
T
I
D
A
V
N
-
R
G
K
I
S
R
F
L
L
K
P
W
E
D
E
D
V
F
K
V
V
E
K
G
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
71.60
37%
-101
- C6 -
2VUH
-
HUPR_RHOCA
B:
[7-133]
---------------
A
I
L
L
V
D
D
E
P
H
S
L
A
A
M
K
L
A
L
E
D
D
-
F
D
V
L
T
-----
A
Q
G
A
E
A
A
I
A
I
L
E
E
E
--
W
V
Q
V
I
I
C
E
Q
R
M
P
G
R
T
G
V
D
F
L
T
E
V
R
E
R
W
P
E
T
V
R
--
I
I
I
T
G
Y
T
D
S
A
S
M
M
A
A
I
N
-
D
A
G
I
H
Q
F
L
T
K
P
W
H
P
E
Q
L
L
S
S
A
R
N
A
A
R
M
F
T
L
A
R
E
N
E
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.52
33%
-109
- C6 -
2RJN
-
?
A:
[8-138]
--------------
Y
T
V
M
L
V
D
D
E
Q
P
I
L
N
S
L
K
R
L
I
K
R
L
G
C
N
I
I
T
-----
F
T
S
P
L
D
A
L
E
A
L
K
G
T
--
S
V
Q
L
V
I
S
D
M
R
M
P
E
M
G
G
E
V
F
L
E
Q
V
A
K
S
Y
P
D
I
E
R
--
V
V
I
S
G
Y
A
D
A
Q
A
T
I
D
A
V
N
-
R
G
K
I
S
R
F
L
L
K
P
W
E
D
E
D
V
F
K
V
V
E
K
G
L
Q
L
A
F
L
R
E
E
N
L
R
L
--
Q
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.08
38%
-98
- C6 -
2VUI
3
HUPR_RHOCA
B:
[3-129]
---------------
A
I
L
L
V
D
D
E
P
H
S
L
A
A
M
K
L
A
L
E
D
D
-
F
D
V
L
T
-----
A
Q
G
A
E
A
A
I
A
I
L
E
E
E
--
W
V
Q
V
I
I
C
D
Q
R
M
P
G
R
T
G
V
D
F
L
T
E
V
R
E
R
W
P
E
T
V
R
--
I
I
I
T
G
Y
T
D
S
A
S
M
M
A
A
I
N
-
D
A
G
I
H
Q
F
L
T
K
P
W
H
P
E
Q
L
L
S
S
A
R
N
A
A
R
M
F
T
L
A
R
E
N
E
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
65.20
31%
-94
- C6 -
3JTE
-
?
A:
[6-128]
----------------
I
L
V
I
D
D
E
S
T
I
L
Q
N
I
K
F
L
L
E
I
D
G
N
E
V
L
T
-----
A
S
S
S
T
E
G
L
R
I
F
T
E
N
CN
S
I
D
V
V
I
T
D
M
K
M
P
K
L
S
G
M
D
I
L
R
E
I
K
K
I
T
P
H
M
A
V
--
I
I
L
T
G
H
G
D
L
D
N
A
I
L
A
M
K
-
E
G
A
F
-
E
Y
L
R
K
P
V
T
A
Q
D
L
S
I
A
I
N
N
A
I
-------
N
R
K
K
L
L
M-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
63.88
31%
-87
- C6 -
1L5Z
5
DCTD_RHIME
A:
[5-146]
---------------
S
V
F
L
I
D
D
D
R
D
L
R
K
A
M
Q
Q
T
L
E
L
A
G
F
T
V
S
S
-----
F
A
S
A
T
E
A
L
A
G
L
S
A
D
--
F
A
G
I
V
I
S
D
I
R
M
P
G
M
D
G
L
A
L
F
R
K
I
L
A
L
D
P
D
L
P
M
--
I
L
V
T
G
H
G
D
I
P
M
A
V
Q
A
I
Q
-
D
G
-
A
Y
D
F
I
A
K
P
F
A
A
D
R
L
V
Q
S
A
R
R
A
E
K
K
R
R
L
V
M
E
N
R
S
L
--
R
R
A
A
E
A
A
S
E
G
L
-
K
L
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
62.98
35%
-98
- C6 -
1KRW
-
NTRC_SALTY
A:
[3-121]
-------------
R
G
I
V
W
V
V
D
D
D
S
S
I
R
W
V
L
E
R
A
L
A
G
A
G
L
T
C
T
T
-----
F
E
N
G
N
E
V
L
A
A
L
A
S
K
--
T
P
D
V
L
L
S
D
I
R
M
P
G
M
D
G
L
A
L
L
K
Q
I
K
Q
R
H
P
M
L
P
V
--
I
I
M
T
A
H
S
D
L
D
A
A
V
S
A
Y
Q
-
Q
G
A
F
-
D
Y
L
P
K
P
F
D
I
D
E
A
V
A
L
V
E
R
A
I
S
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
62.77
31%
-102
- C6 -
2ZWM
3
YYCF_BACSU
A:
[4-117]
---------------
K
I
L
V
V
D
D
E
K
P
I
A
D
I
L
E
F
N
L
R
K
E
G
Y
E
V
H
C
-----
A
H
D
G
N
E
A
V
E
M
V
E
E
L
--
Q
P
D
L
I
L
L
D
I
M
L
P
N
K
D
G
V
E
V
C
R
E
V
R
K
K
Y
D
M
P
I
---
I
M
L
T
A
K
D
--
S
E
I
D
K
V
I
G
L
E
I
G
A
D
D
Y
V
T
K
P
F
S
T
R
E
L
L
A
R
V
K
A
N
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
62.43
31%
-99
- C6 -
2ZWM
3
YYCF_BACSU
B:
[4-117]
---------------
K
I
L
V
V
D
D
E
K
P
I
A
D
I
L
E
F
N
L
R
K
E
G
Y
E
V
H
C
-----
A
H
D
G
N
E
A
V
E
M
V
E
E
L
--
Q
P
D
L
I
L
L
D
I
M
L
P
N
K
D
G
V
E
V
C
R
E
V
R
K
K
Y
D
M
P
I
---
I
M
L
T
A
K
D
--
S
E
I
D
K
V
I
G
L
E
I
G
A
D
D
Y
V
T
K
P
F
S
T
R
E
L
L
A
R
V
K
A
N
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
62.37
32%
-94
- C6 -
3DZD
-
?
A:
[3-117]
----------------
V
L
V
V
D
D
E
E
S
I
T
S
S
L
S
A
I
L
E
E
E
G
Y
H
P
D
T
-----
A
K
T
L
R
E
A
E
K
K
I
K
E
L
--
F
F
P
V
I
V
L
D
V
W
M
P
D
G
D
G
V
N
F
I
D
F
I
K
E
N
S
P
D
S
V
V
--
I
V
I
T
G
H
G
S
V
D
T
A
V
K
A
I
K
-
K
G
-
A
Y
E
F
L
E
K
P
F
S
V
E
R
F
L
L
T
I
K
H
A
F
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
62.29
31%
-86
- C6 -
1L5Y
13
DCTD_RHIME
A:
[5-146]
---------------
S
V
F
L
I
D
D
D
R
D
L
R
K
A
M
Q
Q
T
L
E
L
A
G
F
T
V
S
S
-----
F
A
S
A
T
E
A
L
A
G
L
S
A
D
--
F
A
G
I
V
I
S
D
I
R
M
P
G
M
D
G
L
A
L
F
R
K
I
L
A
L
D
P
D
L
P
M
--
I
L
V
T
G
H
G
D
I
P
M
A
V
Q
A
I
Q
-
D
G
-
A
Y
D
F
I
A
K
P
F
A
A
D
R
L
V
Q
S
A
R
R
A
E
K
K
R
R
L
V
M
E
N
R
S
L
--
R
R
A
A
E
A
A
S
E
G
L
-
K
L
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
62.13
32%
-95
- C6 -
1SD5
7
PDTAR_MYCTU
A:
[16-122]
----------------
V
L
I
A
E
D
E
A
L
I
R
M
D
L
A
E
M
L
R
E
E
G
Y
E
I
V
G
E----
A
G
D
G
Q
E
A
V
E
L
A
E
L
H
--
K
P
D
L
V
I
M
D
V
K
M
P
R
R
D
G
I
D
A
A
S
E
I
A
S
K
R
I
A
P
I
---
V
V
L
T
A
F
S
Q
R
D
L
V
E
R
A
R
D
-
A
G
A
M
-
A
Y
L
V
K
P
F
S
I
S
D
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
61.44
33%
-92
- C6 -
2JRL
-
?
A:
[4-118]
----------------
V
L
V
V
D
D
E
E
S
I
T
S
S
L
S
A
I
L
E
E
E
G
Y
H
P
D
T
-----
A
K
T
L
R
E
A
E
K
K
I
K
E
L
--
F
F
P
V
I
V
L
D
V
W
M
P
D
G
D
G
V
N
F
I
D
F
I
K
E
N
S
P
D
S
V
V
--
I
V
I
T
G
H
G
S
V
D
T
A
V
K
A
I
K
-
K
G
-
A
Y
E
F
L
E
K
P
F
S
V
E
R
F
L
L
T
I
K
H
A
F
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
61.12
31%
-76
- C6 -
1L5Y
9
DCTD_RHIME
B:
[5-149]
---------------
S
V
F
L
I
D
D
D
R
D
L
R
K
A
M
Q
Q
T
L
E
L
A
G
F
T
V
S
S
-----
F
A
S
A
T
E
A
L
A
G
L
S
A
D
--
F
A
G
I
V
I
S
D
I
R
M
P
G
M
D
G
L
A
L
F
R
K
I
L
A
L
D
P
D
L
P
M
--
I
L
V
T
G
H
G
D
I
P
M
A
V
Q
A
I
Q
-
D
G
-
A
Y
D
F
I
A
K
P
F
A
A
D
R
L
V
Q
S
A
R
R
A
E
K
K
R
R
L
V
M
E
N
R
S
L
--
R
R
A
A
E
A
A
S
E
G
L
-
K
L
A
A
A
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
58.97
34%
-76
- C6 -
3FFX
8
CHEY_ECOLI
A:
[2-126]
---------
D
K
E
L
K
F
--
L
V
V
D
D
E
----
S
T
M
R
R
I
V
R
N
L
L
K
E
L
G
F
NN
V
E
E
A
E
D
G
V
D
A
L
N
K
L
Q
A
G
--
G
Y
G
F
V
I
S
D
W
R
M
P
N
M
D
G
L
E
L
L
K
T
I
R
A
D
G
A
M
S
A
L
P
V
L
M
V
T
A
H
A
K
K
E
N
I
I
A
A
A
Q
-
A
G
-
A
S
G
Y
V
V
K
P
F
T
A
A
T
L
E
E
K
L
N
K
I
F
E
K
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------