@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA2962: (2016-02-12 )
MTGLFVTLEGPEGAGKSTNRDYLAERLRERGIEVQLTREPGGTPLAERIRELLLAPSDEPMAADTELLLMFAARAQHLAGVIRPALARGAVVLCDRFTDATYAYQGGGRGLPEARIAALESFVQGDLRPDLTLVFDLPVEIGLARAAARGRLDRFEQEDRRFFEAVRQTYLQRAAQAPERYQVLDAGLPLAEVQAGLDRLLPNLLERLNG
Atome Classification :
(54 SA)
.........10........20........-30---..-.-..-....40........50...---...-.-.60........70........80........90........100....---...110.......120.......130.......140.......150.......160.......170.......180....-...190.......200.......210
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
G
L
F
V
T
L
EGPEGAGKST
N
R
D
Y
L
A
E
R
L
R
E-R----G
I
-
E
-
V
Q
-
L
TREPGGT
P
L
A
E
R
I
R
E
L
LL---APS-D-EPMAA
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
LAR
G
A
V
V
L
C
DRFTD
A
T
Y
A
YQG---GGRGL
P
E
A
R
I
A
A
L
E
S
F
V
Q
GDLRP
D
L
T
L
V
F
DLPVEI
G
L
A
R
A
A
ARG
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
AQAPE
R
Y
Q
V
L
DA-GL
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
LNG
2
PsiBlast_PDB
97.54
100%
-100
- C2 -
4EDH
5
KTHY_PSEAE
A:
[5-212]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
25
PsiBlast_CBE
97.39
100%
-100
- C2 -
4EDH
4
KTHY_PSEAE
B:
[4-213]
M
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
----
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
G
4
PsiBlast_PDB
97.39
100%
-99
- C2 -
4GMD
3
KTHY_PSEAE
A:
[5-212]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
-----
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
7
PsiBlast_PDB
97.29
99%
-104
- C2 -
4E5U
2
KTHY_PSEAE
A:
[5-213]
-
T
G
L
F
V
T
L
E
G
P
E
----
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
-
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
G
30
PsiBlast_CBE
96.60
99%
-104
- C2 -
4E5U
3
KTHY_PSEAE
B:
[5-212]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
--
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
3
PsiBlast_PDB
96.52
100%
-101
- C2 -
4ESH
1
KTHY_PSEAE
A:
[4-212]
M
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
----
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
29
PsiBlast_CBE
96.01
100%
-96
- C2 -
3UXM
1
KTHY_PSEAE
B:
[1-206]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
--
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
---
22
PsiBlast_CBE
95.54
100%
-102
- C2 -
4GMD
4
KTHY_PSEAE
D:
[5-212]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
------------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
23
PsiBlast_CBE
95.30
100%
-101
- C2 -
4GMD
3
KTHY_PSEAE
C:
[5-212]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
-----------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
6
PsiBlast_PDB
95.23
100%
-106
- C2 -
3UXM
3
KTHY_PSEAE
A:
[2-207]
--
G
L
F
V
T
L
E
G
P
E
G
----
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
-----
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
--
27
PsiBlast_CBE
95.10
100%
-98
- C2 -
3UXM
1
KTHY_PSEAE
D:
[2-204]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
-----
28
PsiBlast_CBE
94.86
100%
-106
- C2 -
3UXM
3
KTHY_PSEAE
C:
[1-207]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
---
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
----
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
--
24
PsiBlast_CBE
94.34
100%
-102
- C2 -
4GMD
4
KTHY_PSEAE
B:
[5-211]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
------------
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
--
21
PsiBlast_CBE
94.27
100%
-103
- C2 -
3UWK
1
KTHY_PSEAE
B:
[23-228]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
----------
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
--
5
PsiBlast_PDB
94.22
100%
-104
- C2 -
3UWO
1
KTHY_PSEAE
A:
[11-215]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
-----------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
---
1
PsiBlast_PDB
93.68
100%
-95
- C2 -
3UWK
2
KTHY_PSEAE
A:
[23-227]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
---
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
---
26
PsiBlast_CBE
92.89
100%
-105
- C2 -
3UWO
1
KTHY_PSEAE
B:
[11-213]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
-
R
----
G
I
-
E
-
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
---
A
P
S
-
D
-
E
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
---
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
------------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
-----
31
PsiBlast_CBE
78.53
50%
-102
- C2 -
3V9P
4
KTHY_BURTA
B:
[25-227]
--
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
W
F
C
D
R
L
Q
E
-
R
L
G
PA
G
R
-
H
-
V
V
-
V
T
R
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
-------
N
-
Q
P
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
---
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
V
R
M
P
D
K
F
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
D
S
-
S
E
P
I
A
Q
I
R
K
Q
L
E
G
V
L
A
A
L
------
90
Fugue
77.68
45%
-96
- C2 -
4TMK
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
V
V
V
E
T
L
E
Q
-
L
----
G
I
-
R
D
M
V
-
F
T
R
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
DIK
S
V
G
-
D
-
E
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
GGR
G
---
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
D
-
K
S
I
H
T
I
D
A
T-
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
9
PsiBlast_PDB
77.27
44%
-88
- C2 -
4TMK
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
V
V
V
E
T
L
E
Q
-
L
----
G
I
R
D
-
M
V
-
F
T
R
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
DIK
S
V
G
-
D
-
E
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
---
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
-
D
K
S
I
H
T
I
D
A
-
T
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
70
HHSearch
76.80
52%
-95
- C2 -
3V9P
5
KTHY_BURTA
A:
[23-226]
A
R
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
W
F
C
D
R
L
Q
E
-
R
L
G
P
A
G
R
-
H
-
V
V
-
V
T
R
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
---
N
Q
-----
P
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
---
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
V
R
M
P
---
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
D
S
-
S
E
P
I
A
Q
I
R
K
Q
L
E
G
V
L
A
A
-------
32
PsiBlast_CBE
76.71
42%
-90
- C2 -
3N2I
2
KTHY_VIBCH
B:
[26-234]
-
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
-
N
----
G
I
-
D
H
I
T
-
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
---
E
E
H
P
G
-
E
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
---
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
A
R
G
R
G
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
-
L
A
N
S
D
D
S
V
V
M
I
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
V
N
-
8
PsiBlast_PDB
76.63
50%
-97
- C2 -
3V9P
5
KTHY_BURTA
A:
[25-227]
--
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
W
F
C
D
R
L
Q
E
-
R
L
G
P
A
G
R
-
H
-
V
V
-
V
T
R
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
-------
N
-
Q
P
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
---
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
V
R
M
P
---
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
D
S
-
S
E
P
I
A
Q
I
R
K
Q
L
E
G
V
L
A
A
L
------
10
PsiBlast_PDB
75.94
44%
-90
- C2 -
5TMP
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
V
V
V
E
T
L
E
Q
-
L
----
G
I
R
D
-
M
V
-
F
T
R
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
DIK
S
V
G
-
D
-
E
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
---
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
-
D
K
S
I
H
T
I
D
A
-
T
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
42
PsiBlast_CBE
75.11
37%
-89
- C2 -
4QGH
2
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
-----
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
12
PsiBlast_PDB
74.04
42%
-91
- C2 -
3N2I
2
KTHY_VIBCH
A:
[25-232]
M
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
-
N
----
G
I
-
D
H
I
T
-
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
---
E
E
H
P
G
-
E
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
---
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
A
R
G
--
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
-
L
A
N
S
D
D
S
V
V
M
I
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
---
11
PsiBlast_PDB
73.70
42%
-88
- C2 -
3LV8
8
KTHY_VIBCH
A:
[26-234]
-
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
-
N
----
G
I
-
D
H
I
T
-
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
---
E
E
H
P
G
-
E
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
---
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
-----
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
-
L
A
N
S
D
D
S
V
V
M
I
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
V
N
-
71
HHSearch
73.19
43%
-86
- C2 -
3LV8
8
KTHY_VIBCH
A:
[26-234]
-
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
-
N
----
G
I
-
D
-
H
I
T
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
---
E
E
H
-
P
G
E
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
---
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
-----
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
D
-
D
S
V
V
M
I
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
V
N
-
20
PsiBlast_PDB
73.05
37%
-91
- C2 -
4HEJ
1
KTHY_STAAN
A:
[4-203]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
---
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
----
55
PsiBlast_CBE
73.00
37%
-89
- C2 -
4HDC
1
KTHY_STAAN
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
S
-----
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
49
PsiBlast_CBE
72.88
37%
-88
- C2 -
4QG7
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
S
-----
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
47
PsiBlast_CBE
72.67
37%
-88
- C2 -
4QGA
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
S
-----
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
51
PsiBlast_CBE
72.56
37%
-88
- C2 -
4HLD
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
S
-----
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
53
PsiBlast_CBE
72.46
37%
-87
- C2 -
4HLC
1
KTHY_STAAR
B:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
S
-----
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
44
PsiBlast_CBE
72.03
37%
-91
- C2 -
4QGG
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
41
PsiBlast_CBE
71.95
37%
-85
- C2 -
4XWA
1
KTHY_STAA1
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
S
R
---
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
14
PsiBlast_PDB
71.86
37%
-83
- C2 -
4EAQ
1
KTHY_STAAM
A:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
-------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
----
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
48
PsiBlast_CBE
71.79
37%
-84
- C2 -
4QGA
1
KTHY_STAAR
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
33
PsiBlast_CBE
71.77
37%
-91
- C2 -
4EAQ
1
KTHY_STAAM
B:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-----
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
50
PsiBlast_CBE
71.75
37%
-84
- C2 -
4QG7
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
40
PsiBlast_CBE
71.36
37%
-91
- C2 -
4XWA
2
KTHY_STAA1
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-----
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
46
PsiBlast_CBE
71.23
37%
-85
- C2 -
4QGF
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
-------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
52
PsiBlast_CBE
71.21
37%
-86
- C2 -
4HLD
1
KTHY_STAAR
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
43
PsiBlast_CBE
70.71
37%
-84
- C2 -
4QGH
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
--
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
54
PsiBlast_CBE
70.68
37%
-85
- C2 -
4HLC
1
KTHY_STAAR
A:
[4-203]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
----
74
HHSearch
70.51
40%
-88
* C2 *
3HJN
3
KTHY_THEMA
A:
[1-192]
---
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
L
L
A
Q
Y
L
E
K
-
R
----
G
K
-
K
-
V
I
-
L
K
R
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
---
E
E
E
-----
V
T
P
K
A
E
L
F
L
F
L
A
S
R
N
L
-
L
V
T
E
I
K
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
---
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
K
---
N
R
F
E
-----
K
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
D
G
-
K
R
S
I
E
E
I
H
R
D
V
V
R
E
V
K
R
R
------
45
PsiBlast_CBE
70.40
37%
-83
- C2 -
4QGG
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
17
PsiBlast_PDB
70.09
37%
-86
- C2 -
4GFD
1
KTHY_STAAM
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
19
PsiBlast_PDB
69.88
37%
-85
- C2 -
4HDC
1
KTHY_STAAN
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
18
PsiBlast_PDB
68.92
37%
-86
- C2 -
4GSY
1
KTHY_STAAR
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
--
K
----
D
Y
-
D
-
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
---
E
G
N
-
D
---
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
---
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
59
PsiBlast_CBE
66.65
43%
-74
- C2 -
3HJN
3
KTHY_THEMA
A:
[1-182]
---
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
L
L
A
Q
Y
L
E
K
-
R
----
G
K
-
K
-
V
I
-
L
K
R
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
---
E
E
E
-
V
-
T
P
K
A
---
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
---
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
---
K
---
N
R
F
E
K
--
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
D
G
-
K
R
S
I
E
E
I
H
----------------
58
PsiBlast_CBE
66.32
43%
-73
- C2 -
3HJN
2
KTHY_THEMA
B:
[1-182]
---
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
L
L
A
Q
Y
L
E
K
-
R
----
G
K
-
K
-
V
I
-
L
K
R
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
---
E
E
E
-
V
-
T
P
K
A
---
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
---
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
-------
N
R
F
E
K
--
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
D
G
-
K
R
S
I
E
E
I
H
----------------
62
PsiBlast_CBE
65.14
38%
-87
- C2 -
3LD9
2
KTHY_EHRCR
B:
[21-206]
--
S
M
F
I
T
F
E
G
I
D
G
S
G
K
T
T
Q
S
H
L
L
A
E
Y
L
S
E
I
Y
----
G
V
-
N
N
V
V
-
L
T
R
E
P
G
G
T
L
L
N
E
S
V
R
N
L
L
F
---
K
A
----
Q
G
L
D
S
L
S
E
L
L
F
F
I
A
M
R
R
E
H
F
V
K
I
I
K
P
S
L
M
Q
K
K
I
V
I
C
D
R
F
I
D
S
T
I
A
Y
Q
G
---
Y
G
Q
G
I
D
C
S
L
I
D
Q
L
N
D
L
V
I
-
D
V
Y
P
D
I
T
F
I
I
D
V
---------------------
D
M
E
F
Y
Y
R
V
R
D
G
F
Y
D
I
A
K
K
N
P
H
R
C
H
V
I
---------------------------
60
PsiBlast_CBE
63.23
38%
-81
- C2 -
3LD9
2
KTHY_EHRCR
D:
[21-201]
--
S
M
F
I
T
F
E
G
I
D
G
S
G
K
T
T
Q
S
H
L
L
A
E
Y
L
S
E
I
Y
----
G
V
-
N
N
V
V
-
L
T
R
E
P
G
G
T
L
L
N
E
S
V
R
N
L
L
F
---
K
A
----
Q
G
L
D
S
L
S
E
L
L
F
F
I
A
M
R
R
E
H
F
V
K
I
I
K
P
S
L
M
Q
K
K
I
V
I
C
D
R
F
I
D
S
T
I
A
Y
Q
G
---
Y
G
Q
G
I
D
C
S
L
I
D
Q
L
N
D
L
V
I
-
D
V
Y
P
D
I
T
F
I
I
D
V
D
--------------------
D
M
E
F
Y
Y
R
V
R
D
G
F
Y
D
I
A
K
K
N
P
H
R
C
H
V
I
---------------------------